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Adherence to behavioural intervention in RCT study by the women experiencing domestic violence and attending ANC in a public hospital in India-an analysis 在印度一家公立医院接受非国大治疗的遭受家庭暴力妇女的随机对照试验研究中对行为干预的依从性分析
Pub Date : 2023-03-20 DOI: 10.1016/j.dialog.2023.100126
Meerambika Mahapatro, Sudeshna Roy, Poonam Nayar, Suruchi Panchkaran, Ashwini Jadhav

Background

The paper aims to identify the factors for effective implementation and adherence to the behavioural intervention package by women experiencing domestic violence (DV) and attending ANC in a public hospital.

Methods

A qualitative study was undertaken with 211 pregnant women experiencing DV and attending antenatal care (ANC) at the LN Hospital, New Delhi. The intervention was given to women recruited under the RCT study. The narratives were analysed under two broad themes, impeding and facilitating factors, with nine sub-themes.

Findings

Impeding factors are external factors generated by the structural interaction of the participants, whereas facilitating factors are supplied internally in the trial to eliminate the influence of impeding factors and singulate the factors under study. Our results show that despite the plethora of impeding factors (nine), the overall sum impact of impeding factors falls short of the positive impact of facilitating factors (nine), which were minor adjustments but reinforce participation in the trial and adherence with 97% follow-up rates.

Interpretation

Our study findings are expected to reset the treatment protocol, which entails converting impeding factors into facilitating factors for appropriate adherence and compliance and adequate access and utilization of public services. The sensitization of healthcare providers to the impact of the quality of human interaction on the patient and its impact on the uptake of healthcare services and adherence is needed, particularly in the public hospitals of India.

Funding

Funds received for the research are from the Indian Council of Medical Research (ICMR), New Delhi, Government of India.

背景:本文旨在确定在公立医院接受家庭暴力治疗的妇女有效实施和遵守行为干预一揽子计划的因素。方法对211名在新德里LN医院接受产前护理的家暴孕妇进行定性研究。干预措施是在随机对照试验研究中招募的妇女。在阻碍因素和促进因素这两大主题下,对这些叙述进行了分析,并提出了九个次级主题。阻碍因素是参与者结构性互动产生的外部因素,而促进因素是试验内部提供的,消除阻碍因素的影响,使所研究的因素单一。我们的研究结果显示,尽管有过多的阻碍因素(9个),但阻碍因素的总体影响总和低于促进因素(9个)的积极影响,促进因素是微小的调整,但以97%的随访率加强了试验的参与和依从性。我们的研究结果有望重新制定治疗方案,这需要将阻碍因素转化为促进因素,以实现适当的依从性和依从性,并充分获得和利用公共服务。需要使医疗保健提供者认识到人际交往质量对患者的影响及其对医疗保健服务的接受和依从性的影响,特别是在印度的公立医院。该研究收到的资金来自印度政府新德里的印度医学研究委员会。
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引用次数: 0
Long-term quality of life and work ability among severe COVID-19 survivors: A multicenter study 重症COVID-19幸存者的长期生活质量和工作能力:一项多中心研究
Pub Date : 2023-03-14 DOI: 10.1016/j.dialog.2023.100124
Anshul Jain , Prashant Gupta , Apurva Abhinandan Mittal , Narendra Singh Sengar , Rachna Chaurasia , Neeraj Banoria , Arvind Kankane , Arpita Saxena , Brijendra , Mrinal Sharma

Background

Coronavirus disease 2019 (COVID-19), is known for its variable severity and high infectivity. Though fewer than 15% of infected cases develop severe disease, a major proportion had prolonged stay in the intensive care unit (ICU). Prolonged ICU stay is known to have a long-term impact on behavior and quality of life.8 Therefore, it is likely that patients discharged after severe COVID-19 have issues that persist for long term. The current study aimed to assess the long-term impact of severe COVID-19 on the Quality of life (QOL), sleep pattern, behavior, and workability.

Methods

The current multicenter study adopted a cross-sectional design to analyze data from two tertiary care COVID-19 dedicated hospitals. All experimental procedures were approved by the ethics committee of the M.L.B Medical College. Participants were 20–60 age group who had been admitted to the ICU because of severe COVID-19 and had elapsed at least one and a half year since their discharge. After informed written consent the participants were assessed for: EUROHIS-QOL 8-item index; Workability Score; Quality of sleep; The major depression inventory (MDI) questionnaire; Generalized anxiety disorder 7 item scale (GAD-7); Current global health status score: an innovative subjective scale (1 –10) to determine the current global health status when 5 is the status before COVID-19.

Findings

491 participants were assessed, the median follow-up time after discharge from the hospital was 561·0 days (range, 548–580 days). The mean duration of ICU stay was 8.72 ± 2.85 days. There was significant reduction in the prevalence of obesity, diabetes, and hypertension as compared with discharge time. The mean of EUROHIS-QOL score, workability score, current global health status score was 3.28 ± 0.98, 6.87 ± 0.85, 4.53 ± 1.36 respectively. The mean MDI and anxiety scores were 4.12 ± 1.45 and 18.63 ± 3.28, respectively.

Interpretation

Severe COVID-19 survivors have new-onset psychological disorders and sleep disturbances. Long term quality of life and work ability remains poor after prolong ICU admission secondary to severe COVID-19.

背景2019冠状病毒病(新冠肺炎)以其不同的严重程度和高传染性而闻名。尽管只有不到15%的感染病例发展为严重疾病,但很大一部分人在重症监护室(ICU)呆了很长时间。众所周知,长期入住重症监护室会对行为和生活质量产生长期影响。8因此,严重新冠肺炎后出院的患者可能会出现长期存在的问题。目前的研究旨在评估严重新冠肺炎对生活质量(QOL)、睡眠模式、行为和工作能力的长期影响。方法目前的多中心研究采用横断面设计,分析两所三级护理新冠肺炎专科医院的数据。所有实验程序都得到了M.L.B医学院伦理委员会的批准。参与者为20-60岁年龄组,因严重的新冠肺炎入住重症监护室,出院后至少一年半。知情书面同意后,对参与者进行评估:EUROIS-GOL 8项指数;工作能力得分;睡眠质量;重度抑郁症调查表;广泛性焦虑症7项量表(GAD-7);当前全球健康状况评分:一种创新的主观量表(1-10),用于确定当前全球健康状态,其中5为COVID-19之前的状态。在491名参与者中,出院后的中位随访时间为561.0天(范围为548–580天)。ICU的平均住院时间为8.72±2.85天。与出院时间相比,肥胖、糖尿病和高血压的患病率显著降低。EUROIS-GOL评分、可操作性评分和当前全球健康状况评分的平均值分别为3.28±0.98、6.87±0.85、4.53±1.36。平均MDI和焦虑评分分别为4.12±1.45和18.63±3.28。解释严重的新冠肺炎幸存者有新的心理障碍和睡眠障碍。在严重新冠肺炎导致重症监护室住院时间延长后,长期生活质量和工作能力仍然较差。
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引用次数: 0
Inequities in routine preventive care utilization among persons with overweight/obesity in the United States: An analysis of nativity, racial and ethnic identity, and socioeconomic status 美国超重/肥胖人群常规预防保健利用的不公平:出生、种族和民族认同和社会经济地位的分析
Pub Date : 2023-03-13 DOI: 10.1016/j.dialog.2023.100125
Biplab Kumar Datta , Steven S. Coughlin , Ban Majeed

Extant literature documented various health disparities among immigrants and racial and ethnically marginalized individuals in the United States. However, health disparities in the intersection of nativity and race are generally less visited. This cross-sectional study assessed utilization of routine preventive care among adults with overweight/obesity at the junction of their nativity, racial/ethnic identity, and socioeconomic status (i.e., income and education). Pooling data on 120,184 adults with overweight/obesity from the 2013–2018 waves of the National Health Interview Survey (NHIS), we estimated modified Poisson regressions with robust standard errors to obtain adjusted prevalence rates of preventive care visit, receiving flu shot, and having blood pressure, cholesterol and blood glucose screened. We found that immigrant adults with overweight/obesity had lower rates of utilization of all five preventive care services. However, these patterns varied by racial and ethnic sub-populations. While White immigrants had comparable rates of cholesterol and blood glucose screening, they had 2.7%, 2.9%, and 14.5% lower rates of preventive care visit, blood pressure screening, and getting a flu shot respectively, compared to native-born Whites. These patterns were similar for Asian immigrants as well. Black immigrants, on the other hand, had comparable rates of getting a flu shot and blood glucose screening, and had 5.2%, 4.9%, and 4.9% lower rates of preventive care visit, blood pressure screening, and cholesterol screening respectively. Lastly, the rates of utilization among Hispanic immigrants were significantly lower (ranging from 9.2% to 20%) than those of their native-born counterparts for all five preventive care services. These rates further varied by education, income, and length of stay in the US, within the racial and ethnic sub-groups. Our findings thus suggest a complex relationship between nativity and racial/ethnic identity in relation to preventive care utilization among adults with overweight/obesity.

现存文献记录了美国移民以及种族和族裔边缘化个体之间的各种健康差异。然而,出生地和种族交叉处的健康差异通常很少出现。这项横断面研究评估了超重/肥胖成年人在出生、种族/民族认同和社会经济地位(即收入和教育)方面对常规预防性护理的利用情况。我们汇集了2013-2018年全国健康访谈调查(NHIS)中120184名超重/肥胖成年人的数据,估计了具有稳健标准误差的修正泊松回归,以获得预防性护理就诊、接种流感疫苗以及筛查血压、胆固醇和血糖的调整后患病率。我们发现,超重/肥胖的移民成年人使用所有五种预防性护理服务的比率较低。然而,这些模式因种族和族裔亚群体而异。虽然白人移民的胆固醇和血糖筛查率相当,但与本地出生的白人相比,他们的预防性护理就诊率、血压筛查率和流感疫苗接种率分别低2.7%、2.9%和14.5%。亚洲移民的这种模式也很相似。另一方面,黑人移民接种流感疫苗和血糖筛查的比率相当,预防性护理就诊、血压筛查和胆固醇筛查的比率分别降低5.2%、4.9%和4.9%。最后,西班牙裔移民在所有五项预防性护理服务中的使用率(从9.2%到20%不等)明显低于本地出生的移民。这些比率还因教育、收入和在美国停留的时间长短而有所不同,在种族和族裔亚群体中也有所不同。因此,我们的研究结果表明,在超重/肥胖成年人中,出生和种族/民族认同与预防性护理利用之间存在复杂的关系。
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引用次数: 0
Dietary diversity, nutritional status, and agricultural commercialization: evidence from adult men of rural farm households 饮食多样性、营养状况与农业商业化:来自农村农户成年男性的证据
Pub Date : 2023-03-11 DOI: 10.1016/j.dialog.2023.100121
Olutosin Ademola Otekunrin , Idris Akanbi Ayinde , Rahman Akintayo Sanusi , Oluseye Olusegun Onabanjo

Access to healthy and affordable diet hinged on the realization of Sustainable Development Goal 2, higher productivity and, economic prosperity while it is difficult for a poorly nourished people to achieve optimum production of goods and services. This study assessed whether dietary diversity (DD) and nutritional status of adult men are associated with crop commercialization index (CCI) levels of agricultural households in two states of Southwestern Nigeria. This research utilized 352 farm households, comprising 277 adult male members. The individual version of dietary diversity score (DDS) of 9 food groups was used to calculate adult men’s DDS over a 24-h recall. Anthropometric data was obtained using body mass index (BMI) while CCI levels was estimated for each agricultural household. Logistic regression and ordered logit models were used to examine the determinants of adult men’s dietary diversity and nutritional status respectively. Hundred percent of adult men consumed starchy staples, with 11.2% consuming egg, 5.8% milk and milk products and 0.4% consuming organ meat over 24-h recall. Adult men of CCI 2 and CCI 4 agricultural households recorded overweight prevalence of >20% in Ogun state while the association between DDS and CCI was statistically insignificant suggesting that being a member of any of the CCI households may not guarantee the consumption of healthy diets among adult men. From Logit regression analysis, it is more likely for adult men with higher farm size to attain the minimum DDS of 4 food groups than those with smaller size of farmland (OR = 4.78; 95% CI: 1.94, 11.76; p = 0.001). The age, farm experience, and cassava marketing experience were positively related to the likelihood of obtaining the minimum DDS. For adult men to achieve a healthy diet, their diet pattern must incorporate a more diversified intake of food from different food groups capable of improving their nutritional status. This study emphasized the need for relevant stakeholders to provide adequate nutrition knowledge intervention programmes capable of improving the diets and nutrition of adult men and other members of farm households.

获得健康和负担得起的饮食取决于实现可持续发展目标2,即提高生产力和经济繁荣,而营养不良的人民很难实现商品和服务的最佳生产。本研究评估了尼日利亚西南部两个州成年男性的饮食多样性(DD)和营养状况是否与农业家庭的作物商业化指数(CCI)水平有关。这项研究利用了352个农户,其中包括277名成年男性成员。使用9种食物组的饮食多样性评分(DDS)的个体版本来计算成年男性在24小时内的DDS。使用体重指数(BMI)获得人体测量数据,同时估计每个农业家庭的CCI水平。采用Logistic回归和有序logit模型分别检验了成年男性饮食多样性和营养状况的决定因素。100%的成年男性在24小时内食用淀粉类主食,11.2%的人食用鸡蛋,5.8%的人饮用牛奶和乳制品,0.4%的人食用器官肉。CCI 2和CCI 4农业家庭的成年男性记录了>;奥贡州为20%,而DDS和CCI之间的关联在统计上并不显著,这表明作为任何CCI家庭的成员可能无法保证成年男性食用健康饮食。根据Logit回归分析,农场规模较大的成年男性比农场规模较小的成年男性更有可能获得4种食物组的最低DDS(OR=4.78;95%CI:1.94,11.76;p=0.001)。年龄、农场经验和木薯营销经验与获得最低DDS的可能性呈正相关。成年男性要实现健康饮食,他们的饮食模式必须包括从不同食物组中更多样化地摄入能够改善其营养状况的食物。这项研究强调,相关利益攸关方需要提供足够的营养知识干预方案,以改善成年男子和其他农户成员的饮食和营养。
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引用次数: 1
Dietary diversity, nutritional status, and agricultural commercialization: evidence from adult men of rural farm households. 膳食多样性、营养状况和农业商业化:来自农村农户成年男性的证据。
Pub Date : 2023-03-11 eCollection Date: 2023-12-01 DOI: 10.1016/j.dialog.2023.100121
Olutosin Ademola Otekunrin, Idris Akanbi Ayinde, Rahman Akintayo Sanusi, Oluseye Olusegun Onabanjo

Access to healthy and affordable diet hinged on the realization of Sustainable Development Goal 2, higher productivity and, economic prosperity while it is difficult for a poorly nourished people to achieve optimum production of goods and services. This study assessed whether dietary diversity (DD) and nutritional status of adult men are associated with crop commercialization index (CCI) levels of agricultural households in two states of Southwestern Nigeria. This research utilized 352 farm households, comprising 277 adult male members. The individual version of dietary diversity score (DDS) of 9 food groups was used to calculate adult men's DDS over a 24-h recall. Anthropometric data was obtained using body mass index (BMI) while CCI levels was estimated for each agricultural household. Logistic regression and ordered logit models were used to examine the determinants of adult men's dietary diversity and nutritional status respectively. Hundred percent of adult men consumed starchy staples, with 11.2% consuming egg, 5.8% milk and milk products and 0.4% consuming organ meat over 24-h recall. Adult men of CCI 2 and CCI 4 agricultural households recorded overweight prevalence of >20% in Ogun state while the association between DDS and CCI was statistically insignificant suggesting that being a member of any of the CCI households may not guarantee the consumption of healthy diets among adult men. From Logit regression analysis, it is more likely for adult men with higher farm size to attain the minimum DDS of 4 food groups than those with smaller size of farmland (OR = 4.78; 95% CI: 1.94, 11.76; p = 0.001). The age, farm experience, and cassava marketing experience were positively related to the likelihood of obtaining the minimum DDS. For adult men to achieve a healthy diet, their diet pattern must incorporate a more diversified intake of food from different food groups capable of improving their nutritional status. This study emphasized the need for relevant stakeholders to provide adequate nutrition knowledge intervention programmes capable of improving the diets and nutrition of adult men and other members of farm households.

获得健康和负担得起的饮食关系到可持续发展目标 2 的实现、更高的生产力和经济繁荣,而营养不良的人很难实现商品和服务的最佳生产。本研究评估了尼日利亚西南部两个州农户的膳食多样性(DD)和成年男性的营养状况是否与农作物商业化指数(CCI)水平相关。这项研究利用了 352 个农户,其中包括 277 名成年男性成员。研究人员使用 9 个食物组的个人版膳食多样性评分 (DDS) 计算成年男性在 24 小时内的膳食多样性评分。使用体重指数(BMI)获得人体测量数据,同时估算每个农户的 CCI 水平。逻辑回归和有序对数模型分别用于研究成年男性膳食多样性和营养状况的决定因素。在 24 小时的回忆中,100% 的成年男性食用淀粉类主食,11.2% 食用鸡蛋,5.8% 食用牛奶和奶制品,0.4% 食用内脏肉类。在奥贡州,CCI 2 和 CCI 4 农业家庭的成年男性超重率超过 20%,而 DDS 与 CCI 之间的关系在统计上并不显著,这表明作为任何一个 CCI 家庭的成员并不能保证成年男性食用健康饮食。从 Logit 回归分析来看,与耕地面积较小的成年男性相比,耕地面积较大的成年男性更有可能达到 4 种食物的最低 DDS(OR = 4.78;95% CI:1.94,11.76;P = 0.001)。年龄、农场经验和木薯销售经验与获得最低 DDS 的可能性呈正相关。成年男性要实现健康饮食,其饮食模式必须包括更多样化的不同食物类别的摄入,以改善其营养状况。这项研究强调,相关利益方需要提供足够的营养知识干预计划,以改善成年男性和其他农户成员的饮食和营养状况。
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引用次数: 0
Effect of an educational intervention on diet and physical activity among school-aged adolescents in Delhi -The i-PROMISe (PROMoting health literacy in Schools) Plus Study 教育干预对德里学龄青少年饮食和体育活动的影响——i-PROMISe(促进学校健康素养)加研究
Pub Date : 2023-03-08 DOI: 10.1016/j.dialog.2023.100123
Tina Rawal , Jean W.M. Muris , Vijay Kumar Mishra , Monika Arora , Nikhil Tandon , Onno C.P. van Schayck

Purpose

Emerging lifestyle changes due to rapid urbanization have led to an epidemiological transition and the rising prevalence of obesity is responsible for major non-communicable diseases (NCDs) which have further aggravated due to the COVID-19 pandemic. This study aims to assess the effectiveness of a comprehensive school-based intervention on diet and physical activity-related behavior of adolescents.

Methods

In 2019, a cluster-randomized controlled trial was conducted in randomly selected (n = 8) private schools. A 2-year intervention program was implemented over consecutive academic years (2019–2020 and 2020–2021) with students who were in the 6th and 7th grades when the study began. Four schools were randomly assigned to the intervention (n = 794) and four schools to the control group (n = 774).

Results

The difference in changes in diet and physical-activity-related behaviors of the students between the intervention and control schools were not significant in the intention to treat analysis probably due to the large drop-out due to COVID-19 measures: 304 students were available for follow-up in the intervention group and 122 in the control group (391 cases were excluded to make data comparable with baseline survey). The intake of vegetables (once a day) [β = 0.35, OR = 1.42, 95% CI (1.03, 1.95)] in the per-protocol analysis has increased among adolescents in the intervention group as compared to the control group.

Conclusion

The findings of this study indicated a positive effect of the intervention on diet and physical-activity-related changes in the expected direction and highlights the importance of addressing such behavior to prevent obesity among adolescents and thus NCDs in the later stage of life.

目的快速城市化导致的生活方式的新变化导致了流行病学的转变,肥胖患病率的上升是主要非传染性疾病(NCDs)的原因,这些疾病因新冠肺炎大流行而进一步恶化。本研究旨在评估学校综合干预对青少年饮食和体育活动相关行为的有效性。方法2019年,在随机选择(n=8)所私立学校进行了一项整群随机对照试验。研究开始时,对6年级和7年级的学生实施了为期2年的连续学年(2019-2020年和2020-2021年)的干预计划。将4所学校随机分为干预组(n=794)和4所学校分为对照组(n=774)干预组可用于随访,对照组可用于122例随访(391例被排除在外,以使数据与基线调查具有可比性)。根据方案分析,与对照组相比,干预组青少年的蔬菜摄入量(每天一次)[β=0.35,OR=1.42,95%CI(1.03,1.95)]有所增加。结论这项研究的结果表明,干预措施对饮食和体育活动相关的变化产生了积极的影响,并强调了解决这种行为对预防青少年肥胖以及非传染性疾病的重要性。
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引用次数: 0
A global comparative study of wealth-pain gradients: Investigating individual- and country-level associations 财富-痛苦梯度的全球比较研究:调查个人和国家层面的关联
Pub Date : 2023-03-08 DOI: 10.1016/j.dialog.2023.100122
Zachary Zimmer , Anna Zajacova , Kathryn Fraser , Daniel Powers , Hanna Grol-Prokopczyk

Pain is a significant yet underappreciated dimension of population health. Its associations with individual- and country-level wealth are not well characterized using global data. We estimate both individual- and country-level wealth inequalities in pain in 51 countries by combining data from the World Health Organization's World Health Survey with country-level contextual data. Our research concentrates on three questions: 1) Are inequalities in pain by individual-level wealth observed in countries worldwide? 2) Does country-level wealth also relate to pain prevalence? 3) Can variations in pain reporting also be explained by country-level contextual factors, such as income inequality? Analytical steps include logistic regressions conducted for separate countries, and multilevel models with random wealth slopes and resultant predicted probabilities using a dataset that pools information across countries. Findings show individual-level wealth negatively predicts pain almost universally, but the association strength differs across countries. Country-level contextual factors do not explain away these associations. Pain is generally less prevalent in wealthier countries, but the exact nature of the association between country-level wealth and pain depends on the moderating influence of country-level income inequality, measured by the Gini index. The lower the income inequality, the more likely it is that poor countries experience the highest and rich countries the lowest prevalence of pain. In contrast, the higher the income inequality, the more nonlinear the association between country-level wealth and pain reporting such that the highest prevalence is seen in highly nonegalitarian middle-income countries. Our findings help to characterize the global distribution of pain and pain inequalities, and to identify national-level factors that shape pain inequalities.

疼痛是人口健康的一个重要但未得到充分重视的方面。它与个人和国家层面财富的关系不能很好地用全球数据来描述。我们将世界卫生组织世界卫生调查的数据与国家层面的背景数据相结合,估计了51个国家的个人和国家层面的财富不平等。我们的研究集中在三个问题上:1)在世界各国是否观察到个人财富水平上的痛苦不平等?2)国家层面的财富是否也与疼痛患病率有关?3)疼痛报告的差异是否也可以用国家层面的背景因素(如收入不平等)来解释?分析步骤包括针对不同国家进行的逻辑回归,以及使用汇集各国信息的数据集建立的具有随机财富斜率和由此产生的预测概率的多层模型。研究结果显示,个人财富水平几乎普遍与疼痛呈负相关,但这种关联的强度因国家而异。国家层面的背景因素并不能解释这些关联。疼痛在较富裕的国家通常不那么普遍,但国家财富与疼痛之间的确切联系取决于国家收入不平等的缓和影响,这是由基尼指数衡量的。收入不平等程度越低,就越有可能出现贫穷国家疼痛发生率最高,而富裕国家疼痛发生率最低的情况。相反,收入不平等程度越高,国家财富与疼痛报告之间的关系就越非线性,因此,在高度不平等的中等收入国家,疼痛报告的患病率最高。我们的研究结果有助于描述疼痛和疼痛不平等的全球分布,并确定形成疼痛不平等的国家层面因素。
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引用次数: 1
The effect of the Universal Test and Treat policy uptake on CD4 count testing and incidence of opportunistic infections among people living with HIV infection in Cameroon: a retrospective analysis of routine data 普及检测和治疗政策对喀麦隆HIV感染者CD4计数检测和机会性感染发生率的影响:常规数据的回顾性分析
Pub Date : 2023-02-26 DOI: 10.1016/j.dialog.2023.100120
C.E. Bekolo , S.A. Ndeso , C.P. Gougue , L.L. Moifo , N. Mangala , P. Tchendjou , E. Mboh , J. Ateudjieu , N. Tendongfor , D.S. Nsagha , G.E. Halle-Ekane , S.P. Choukem

Background

Cameroon adopted and started implementing in 2016, the ‘universal test and treat’ (UTT) guidelines to fast-track progress towards the 95-95-95 ambitious targets to end the HIV epidemic. UTT has shown inconsistent results elsewhere and has not yet been assessed in Cameroon. We aimed to evaluate the effectiveness of this novel approach on the quality of care and health outcomes of people living with HIV (PLHIV).

Methods

A retrospective cohort design was conducted at The Nkongsamba Regional Hospital, using routine clinical service delivery data to measure uptake levels of UTT and CD4 testing, and to compare the incidence of opportunistic infections (OI) between PLHIV initiated on ART based on the “Universal Test and Treat” strategy and those initiated on ART based on the standard deferred approach between 2002 and 2020. Kaplan Meier plots and log-rank tests were used to compare OI events between the pre-UTT and post-UTT eras. The Cox regression model was used to screen for factors independently associated with the risk of acquisition of OI.

Results

The uptake of UTT ranged from 39.1% to 92.8% while baseline CD4 count testing reduced drastically from 89.4% to 0.4% between 2016 to 2020 respectively. The median delay in ART initiation declined significantly from 21 days (IQR: 9 – 113) in the pre-UTT era to the same day of diagnosis (IQR: 0 – 2) in the UTT era (p < 0.001). The incidence of all OI events reported was over five times higher during the UTT era than in the pre-UTT era [aHR = 5.55 (95% CI: 3.18 – 9.69), p < 0.001].

Conclusion

The UTT policy has been effectively rolled out and has contributed to improved access to rapid and immediate ART initiation, but a higher incidence of OIs was observed with a rollback of baseline CD4 testing. We advocate for a return to routine baseline CD4 measurement to identify PLHIV who should benefit from interventions to prevent OIs for optimal outcomes under the UTT approach.

喀麦隆于2016年通过并开始实施“普遍检测和治疗”(UTT)指南,以快速实现终结艾滋病毒流行的95-95-95宏伟目标。UTT在其他地方显示出不一致的结果,尚未在喀麦隆进行评估。我们旨在评估这种新方法对艾滋病毒感染者(PLHIV)的护理质量和健康结果的有效性。方法在Nkongsamba地区医院进行回顾性队列设计,使用常规临床服务提供数据测量UTT和CD4检测的吸收水平,并比较2002年至2020年期间基于“普遍检测和治疗”策略开始抗逆转录病毒治疗的hiv感染者和基于标准延迟方法开始抗逆转录病毒治疗的hiv感染者的机会性感染(OI)发生率。Kaplan Meier图和log-rank检验用于比较utt前后的OI事件。Cox回归模型用于筛选与成骨不全风险独立相关的因素。结果2016年至2020年期间,UTT使用率为39.1%至92.8%,基线CD4计数检测从89.4%大幅下降至0.4%。ART启动的中位延迟从UTT前的21天(IQR: 9 - 113)显著下降到UTT时代诊断当天(IQR: 0 - 2) (p <0.001)。UTT时代报告的所有成骨不全事件的发生率比UTT前时代高出5倍以上[aHR = 5.55 (95% CI: 3.18 - 9.69), p <0.001]。UTT政策已得到有效推广,并有助于改善快速和立即开始抗逆转录病毒治疗的可及性,但随着基线CD4检测的回落,观察到oi的发生率较高。我们提倡恢复常规的基线CD4测量,以确定哪些PLHIV患者应该从干预措施中受益,以防止在UTT方法下获得最佳结果。
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引用次数: 1
Multiple socioeconomic risks and cognitive impairment among older men and women in India 印度老年男女的多重社会经济风险和认知障碍
Pub Date : 2023-02-26 DOI: 10.1016/j.dialog.2023.100119
T. Muhammad , Manacy Pai , Manish Kumar , T.V. Sekher

Introduction

Socioeconomic status (SES) is negatively associated with innumerable health outcomes, including cognitive functioning. Yet much remains undiscovered about SES patterns in later-life cognition in low-and middle-income countries (LMICs). The purpose of this study was to examine the association between separate and combined socioconomic risks and cognitive impairment among older adults in India. Further, given gender disparities in later life cognitive functioning and SES, the study examines the associations between socioeconomic risks and cognitive impairment separately, for older men and women.

Methods

Data come from the 2017–18, first wave of the Longitudinal Aging Study in India (LASI), with 31,464 older adults aged 60 years and above. Cognitive impairment was assessed using multiple broad measures of memory, orientation, arithmetic function, and visuo-spatial construction skills. We present descriptive statistics along with cross-tabulation of the outcome variable. Additionally, binary logistic regression analysis was used to test the association between outcome and explanatory variables. SES is measured using education, paid work status, and household wealth measured using monthly per-capita consumption expenditure (MPCE).

Results

A proportion of 7.14% of the older men and 20.03% of older women reported cognitive impairment. The odds of cognitive impairment were higher among uneducated older men and women, and older men and women in lowest wealth quintile. Surprisingly, older women without current or prior work history report lower odds of cognitive impairment compared to their peers in labor force. While odds of cognitive impairment are higher among non-working older men, this association is not statistically significant. In older men, the odds of cognitive impairment were 5.34, 7.14, and 13.05 times higher with one, two, and three risk factors, respectively, compared with those with no risk exposure. A similar trend was observed for women but with comparatively lower odds.

Conclusions

Our findings underscore the need to distinguish between varying elements of SES to construct “upstream” health policies and programs that redistribute resources. In particular, the findings support the use of multiple SES indicators in identifying older adults most susceptible to cognitive deficits, and planning gender-based interventions to improve cognitive health in late life.

社会经济地位(SES)与包括认知功能在内的许多健康结果呈负相关。然而,在低收入和中等收入国家(LMICs),社会经济地位模式对晚年认知的影响仍有许多未被发现。本研究的目的是研究印度老年人单独和综合社会经济风险与认知障碍之间的关系。此外,考虑到晚年认知功能和社会经济地位的性别差异,该研究分别考察了老年男性和女性的社会经济风险与认知障碍之间的关系。方法数据来自2017-18年印度纵向老龄化研究(LASI)的第一波,共有31,464名60岁及以上的老年人。认知障碍评估使用多种广泛的测量记忆,定向,算术功能和视觉空间构建技能。我们提出了描述性统计以及结果变量的交叉表。此外,采用二元逻辑回归分析来检验结果与解释变量之间的相关性。社会经济地位是用教育、有偿工作状况和家庭财富来衡量的,用每月人均消费支出(MPCE)来衡量。结果老年男性和老年女性分别有7.14%和20.03%存在认知功能障碍。未受教育的老年男性和女性,以及处于最低财富五分之一的老年男性和女性,出现认知障碍的几率更高。令人惊讶的是,与劳动力中的同龄人相比,没有当前或以前工作历史的老年女性报告的认知障碍几率较低。虽然不工作的老年男性患认知障碍的几率更高,但这种关联在统计上并不显著。在老年男性中,有一种、两种和三种危险因素的人患认知障碍的几率分别是没有危险因素的人的5.34倍、7.14倍和13.05倍。女性也有类似的趋势,但几率相对较低。结论:研究结果强调需要区分社会经济状况的不同要素,以构建资源再分配的“上游”卫生政策和规划。特别是,研究结果支持使用多种SES指标来识别最容易出现认知缺陷的老年人,并规划基于性别的干预措施,以改善晚年的认知健康。
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引用次数: 2
The bibliometric landscape of infectious disease research in Panama (1990–2019) 巴拿马传染病研究文献计量学概况(1990-2019年)
Pub Date : 2023-02-24 DOI: 10.1016/j.dialog.2023.100117
Jose R. Loaiza , Rolando A. Gittens , Robinson Zapata , Blas Armien , José González-Santamaría , Gabriel Z. Laporta , Leticia Franco

Background

This work aims to analyze the landscape of scientific publications on subjects related to One Health and infectious diseases in Panama. The research questions are: How does the One Health research landscape look like in Panama? Are historical research efforts aligned with the One Health concept? What infectious diseases have received more attention from the local scientific community since 1990?

Methods

Boolean searches on the Web of Science, SCOPUS and PubMed were undertaken to evaluate the main trends of publications related to One Health and infectious disease research in the country of Panama, between 1990 and 2019.

Results

4546 publications were identified since 1990, including 3564 peer-reviewed articles interconnected with One Health related descriptors, and 211 articles focused particularly on infectious diseases. A pattern of exponential growth in the number of publications with various contributions from Panamanian institutions was observed. The rate of multidisciplinary research was moderate, whereas those of interinstitutional and intersectoral research ranged from low to very low. Research efforts have centered largely on protozoan, neglected and arthropod-borne diseases with a strong emphasis on malaria, Chagas and leishmaniasis.

Conclusion

Panama has scientific capabilities on One Health to tackle future infectious disease threats, but the official collaboration schemes and strategic investment to develop further competencies need to be conciliated with modern times, aka the pandemics era. The main proposition here, addressed to the government of Panama, is to launch a One Health regional center to promote multidisciplinary, interinstitutional and intersectoral research activities in Panama and beyond.

背景这项工作旨在分析巴拿马与“一个健康”和传染病相关主题的科学出版物的现状。研究问题是:“一个健康”研究在巴拿马的情况如何?历史研究工作是否与“一个健康”概念一致?自1990年以来,哪些传染病更受当地科学界的关注?方法在Web of Science、SCOPUS和PubMed上进行布尔搜索,以评估1990年至2019年间巴拿马国家与One Health和传染病研究相关的出版物的主要趋势。结果自1990年以来,共发现546篇出版物,包括3564篇与One Health相关描述符相互关联的同行评审文章,211篇文章特别关注传染病。据观察,巴拿马各机构作出各种贡献的出版物数量呈指数级增长。多学科研究的比率适中,而机构间和跨部门研究的比率从低到极低不等。研究工作主要集中在原生动物、被忽视的和节肢动物传播的疾病上,重点是疟疾、查加斯病和利什曼病。结论巴拿马在“一个健康”方面具有应对未来传染病威胁的科学能力,但发展进一步能力的官方合作计划和战略投资需要与现代,即流行病时代相协调。这里向巴拿马政府提出的主要建议是建立一个“一个健康”区域中心,以促进巴拿马及其他地区的多学科、机构间和跨部门研究活动。
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引用次数: 0
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Dialogues in health
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