Pub Date : 2025-12-01Epub Date: 2025-07-09DOI: 10.1007/s00347-025-02289-5
Colya N Englisch, Boris V Stanzel, Clemens N Rudolph, Karl T Boden, Peter Szurman, Philip Wakili
{"title":"[Foveal focal choroidal excavation].","authors":"Colya N Englisch, Boris V Stanzel, Clemens N Rudolph, Karl T Boden, Peter Szurman, Philip Wakili","doi":"10.1007/s00347-025-02289-5","DOIUrl":"10.1007/s00347-025-02289-5","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"945"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-04DOI: 10.1007/s00347-025-02341-4
Alexander K Schuster, Caroline Brandl, Robert P Finger
{"title":"[Nutrition and dietary supplements in eye diseases-Part 2: glaucoma and dry eye].","authors":"Alexander K Schuster, Caroline Brandl, Robert P Finger","doi":"10.1007/s00347-025-02341-4","DOIUrl":"https://doi.org/10.1007/s00347-025-02341-4","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":"122 12","pages":"948-949"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-07-10DOI: 10.1007/s00347-025-02271-1
Lena Spickermann, Philip Maier, Arnd Heiligenhaus, Thabo Lapp
{"title":"[Copper-affine antibodies in Descemet's membrane as a rare clinical manifestation of multiple myeloma-Case report and literature review].","authors":"Lena Spickermann, Philip Maier, Arnd Heiligenhaus, Thabo Lapp","doi":"10.1007/s00347-025-02271-1","DOIUrl":"10.1007/s00347-025-02271-1","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"985-989"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1007/s00347-025-02357-w
Sundaram Natarajan, Mauricio Bayram-Suverza, Itzel Aguilar-Valdez, Mary Lady González-Suriel
Endophthalmitis secondary to microbial keratitis (MK) is a rare but devastating ophthalmic emergency characterized by diagnostic and therapeutic challenges due to poor corneal clarity. Although it accounts for less than 10% of cases of exogenous endophthalmitis, it often results in poor visual outcomes or enucleation. The most common causative organisms include Staphylococcus spp., Pseudomonas spp., and Fusarium spp., with rising concerns about antimicrobial resistance. Several risk factors have been identified, including the use of topical corticosteroids, systemic immunosuppression, and fungal infections, particularly those caused by Fusarium. Early and aggressive management is essential, combining intravitreal antimicrobials with surgery to reduce the microbiological load. When corneal opacity limits visualization, a combined approach involving temporary keratoprosthesis, penetrating keratoplasty, and pars plana vitrectomy may offer a chance to salvage the eye. This narrative review synthesizes the current understanding of MK-associated endophthalmitis and presents updated management strategies to optimize visual and anatomical outcomes in these severe cases.
{"title":"Endophthalmitis with keratitis-how to manage severe cases? : A narrative review.","authors":"Sundaram Natarajan, Mauricio Bayram-Suverza, Itzel Aguilar-Valdez, Mary Lady González-Suriel","doi":"10.1007/s00347-025-02357-w","DOIUrl":"https://doi.org/10.1007/s00347-025-02357-w","url":null,"abstract":"<p><p>Endophthalmitis secondary to microbial keratitis (MK) is a rare but devastating ophthalmic emergency characterized by diagnostic and therapeutic challenges due to poor corneal clarity. Although it accounts for less than 10% of cases of exogenous endophthalmitis, it often results in poor visual outcomes or enucleation. The most common causative organisms include Staphylococcus spp., Pseudomonas spp., and Fusarium spp., with rising concerns about antimicrobial resistance. Several risk factors have been identified, including the use of topical corticosteroids, systemic immunosuppression, and fungal infections, particularly those caused by Fusarium. Early and aggressive management is essential, combining intravitreal antimicrobials with surgery to reduce the microbiological load. When corneal opacity limits visualization, a combined approach involving temporary keratoprosthesis, penetrating keratoplasty, and pars plana vitrectomy may offer a chance to salvage the eye. This narrative review synthesizes the current understanding of MK-associated endophthalmitis and presents updated management strategies to optimize visual and anatomical outcomes in these severe cases.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-11-20DOI: 10.1007/s00347-025-02354-z
Anna M Welzel, Pascal Plein, Stephanie D Grabitz, Julia V Stingl, Esther M Hoffmann, Alexander K Schuster
Glaucoma is one of the main causes of visual impairment and blindness in Germany and globally. The potential impact of nutrition and diatery supplements on the progression and management of this disease is a question that arises frequently in clinical practice. This article aims to offer a comprehensive overview of the current literature.
{"title":"[Nutrition and dietary supplementation and glaucoma].","authors":"Anna M Welzel, Pascal Plein, Stephanie D Grabitz, Julia V Stingl, Esther M Hoffmann, Alexander K Schuster","doi":"10.1007/s00347-025-02354-z","DOIUrl":"10.1007/s00347-025-02354-z","url":null,"abstract":"<p><p>Glaucoma is one of the main causes of visual impairment and blindness in Germany and globally. The potential impact of nutrition and diatery supplements on the progression and management of this disease is a question that arises frequently in clinical practice. This article aims to offer a comprehensive overview of the current literature.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":"950-958"},"PeriodicalIF":0.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1007/s00347-025-02350-3
Juliane Klon, Mitja Alexander Heinrich, Laszlo Kiraly
We report on two cases of transient maculopathy following uneventful cataract surgery with intracameral administration of cefuroxime. Both patients achieved a visual acuity of no more than 20/200 on day 1 after surgery. Optical coherence tomography revealed a neurosensory detachment of the retina with schisis-like alterations in the outer nuclear layer. These findings completely resolved within 6 days of treatment with prednisolone acetate and nepafenac eye drops, resulting in full visual recovery.Intracameral administration of antibiotics, in Europe as cefuroxime 1 mg/0.1 ml, is recommended for endophthalmitis prophylaxis at the end of cataract surgery. At the same time, an association appears to exist between the rare occurrence of specific maculopathies and the application of cefuroxime, particularly in cases of overdose, but also sporadically. Patients who have undergone pars plana or anterior vitrectomy apparently have an inherently higher risk of developing maculopathy. Transient cefuroxime maculopathy usually has a benign, self-limiting course. Cataract surgeons should be aware of this condition and avoid overdosing that otherwise safe and effective drug.
{"title":"[Transient maculopathy after intracameral injection of cefuroxime].","authors":"Juliane Klon, Mitja Alexander Heinrich, Laszlo Kiraly","doi":"10.1007/s00347-025-02350-3","DOIUrl":"https://doi.org/10.1007/s00347-025-02350-3","url":null,"abstract":"<p><p>We report on two cases of transient maculopathy following uneventful cataract surgery with intracameral administration of cefuroxime. Both patients achieved a visual acuity of no more than 20/200 on day 1 after surgery. Optical coherence tomography revealed a neurosensory detachment of the retina with schisis-like alterations in the outer nuclear layer. These findings completely resolved within 6 days of treatment with prednisolone acetate and nepafenac eye drops, resulting in full visual recovery.Intracameral administration of antibiotics, in Europe as cefuroxime 1 mg/0.1 ml, is recommended for endophthalmitis prophylaxis at the end of cataract surgery. At the same time, an association appears to exist between the rare occurrence of specific maculopathies and the application of cefuroxime, particularly in cases of overdose, but also sporadically. Patients who have undergone pars plana or anterior vitrectomy apparently have an inherently higher risk of developing maculopathy. Transient cefuroxime maculopathy usually has a benign, self-limiting course. Cataract surgeons should be aware of this condition and avoid overdosing that otherwise safe and effective drug.</p>","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-11DOI: 10.1007/s00347-025-02338-z
Clemens N Rudolph, Colya N Englisch, Peter Szurman, Philip Wakili
{"title":"[Traumatic iridodialysis].","authors":"Clemens N Rudolph, Colya N Englisch, Peter Szurman, Philip Wakili","doi":"10.1007/s00347-025-02338-z","DOIUrl":"https://doi.org/10.1007/s00347-025-02338-z","url":null,"abstract":"","PeriodicalId":72808,"journal":{"name":"Die Ophthalmologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145497633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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