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Feasibility of Using the Brazilian Version of the GloboDiet Software to Collect Dietary Intake Data 使用巴西版GloboDiet软件收集膳食摄入量数据的可行性
Pub Date : 2023-01-05 DOI: 10.3390/dietetics2010004
Gustavo Andrade, L. T. Cacau, E. De Carli, P. Lotufo, I. Benseñor, D. Marchioni
Technological advances, such as the GloboDiet software, have enabled the development of instruments to standardize dietary data collection through the 24-h dietary recall (24HR). Thus, the aim of this study was to evaluate the feasibility of using the Brazilian version of the GloboDiet software. The 24HR method guided by the GloboDiet software was applied by face-to-face (n = 2093) interviews and a second measurement by telephone (n = 1084) interviews with participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The adherence rate was calculated using data from control worksheets filled out by interviewers, whereas the Chi-square test was used to assess differences between sociodemographic groups and the participants’ final adherence status. For the interview’s duration, the data were presented as the median and the interquartile range—IQR (Q1–Q3 (25–75%)). Non-parametric tests were used to assess differences among individuals in terms of the total duration and stages of the interview. Adherence rates were 82.8% face-to-face and 68.4% telephone interviews. The total duration of the face-to-face and telephone interviews was 30.7 (IQR, 23.3–40.7) and 35.3 (IQR, 25.3–49.7) minutes (p < 0.001). These results evidence that the GloboDiet software is viable for the routine of an epidemiological study.
技术进步,如GloboDiet软件,使得通过24小时饮食召回(24HR)来标准化饮食数据收集的工具得以开发。因此,本研究的目的是评估使用巴西版GloboDiet软件的可行性。采用GloboDiet软件指导的24HR方法,对来自巴西成人健康纵向研究(ELSA-Brasil)的参与者进行面对面访谈(n = 2093)和第二次电话访谈(n = 1084)。依从率是使用由采访者填写的对照工作表中的数据来计算的,而卡方检验则用于评估社会人口统计学群体和参与者最终依从状态之间的差异。在访谈期间,数据被表示为中位数和四分位数范围- iqr (Q1-Q3(25-75%))。使用非参数测试来评估个人在访谈的总持续时间和阶段方面的差异。依从率为82.8%的面对面访谈和68.4%的电话访谈。面对面访谈和电话访谈的总时长分别为30.7 (IQR, 23.3 ~ 40.7)和35.3 (IQR, 25.3 ~ 49.7) min (p < 0.001)。这些结果证明GloboDiet软件在流行病学研究中是可行的。
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引用次数: 0
Factors Associated with Risk of Diabulimia in Greek Adult Population with Type 1 Diabetes Mellitus 希腊成年1型糖尿病患者患糖尿病的相关因素
Pub Date : 2023-01-04 DOI: 10.3390/dietetics2010003
Kiriaki Apergi, M. Romanidou, H. Abdelkhalek, F. Gonidakis
Background: Diabulimia is associated with “resistance to treatment”, impaired glycemic control, and increased risk of diabetic complications. The aim of this study was to explore the possible lifestyle and diet factors associated with diabulimia using the “Diabetes Eating Problem Survey-Revised” (DEPS-R), a questionnaire assessing the risk of diabulimia in patients with T1DM. Methods: 100 outpatients with a diagnosis of T1DM for over a year, from two hospitals in Athens, Greece were asked to complete a questionnaire about their medical history and lifestyle behaviors along with the Eating Attitudes Test (EAT-26), the Beck Depression Scale (BDI-II) and the DEPS-R. Results: Multivariate linear regression analysis showed statistically significant associations between DEPS-R score and HbA1c% levels (b = 4.447, 95% CI 3.220–5.675), sex (male) (b = −4.413, 95% CI −8.778–−0.047, weight perception higher than normal (b = 9.896, 95% CI 5.266–14.526), time spent walking minutes per week (b= −0.019, 95% CI −0.031–−0.006), having received diabetes nutritional education (b = −5.128, 95%CI −10.141–−0.115), eating breakfast (b = −6.441, 95% CI −11.047–−1.835) and having a first relative diagnosed with an eating disorder (b = 6.164, 95%CI 0.030–12.298). The presence of these factors could help highlight the profile of potential individuals at risk of diabulimia and enhance preventive interventions.
背景:糖尿病与“治疗耐药性”、血糖控制受损和糖尿病并发症风险增加有关。本研究的目的是使用“糖尿病饮食问题调查修订版”(DEPS-R)来探索与糖尿病相关的可能的生活方式和饮食因素,这是一份评估T1DM患者患糖尿病风险的问卷。方法:要求来自希腊雅典两家医院的100名诊断为T1DM的门诊患者填写一份关于他们的病史和生活方式行为的问卷,以及饮食态度测试(EAT-26)、贝克抑郁量表(BDI-II)和DEPS-R。结果:多变量线性回归分析显示,DEPS-R评分与HbA1c%水平(b=4.447,95%CI 3.220–5.675)、性别(男性)(b=-4.413,95%CI−8.778–−0.047)、体重感知高于正常水平(b=9.896,95%CI 5.266–14.526)、每周步行时间(b=-0.019,95%CI−0.031–−0.006)之间存在统计学显著相关性,接受过糖尿病营养教育(b=−5.128,95%CI−10.141–−0.115),吃过早餐(b=–6.441,95%CI–11.047–−1.835),有一位第一亲属被诊断患有饮食障碍(b=6.164,95%CI 0.030–12.298)。这些因素的存在有助于突出潜在糖尿病风险个体的特征,并加强预防干预。
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引用次数: 0
Taking Stock of Fruit and Vegetable Consumption in Canada: Trends and Challenges 盘点加拿大的水果和蔬菜消费:趋势和挑战
Pub Date : 2023-01-03 DOI: 10.3390/dietetics2010002
Sylvain Charlebois, J. Music, H. Rupasinghe
Purpose: A diet rich in fruits and vegetables is vital for prolonged health and wellness. Yet, the consumption of fruits and vegetables remains low in some regions. Methodology: This exploratory quantitative study utilized a web-based survey instrument to probe the likelihood of consumption by Canadian consumers. Canadians who have lived in the country for 12 months or more and were 18 years of age or older were surveyed. Care was given to get a representative sample from all Canadian regions. Findings: Barriers to produce consumption include cost (39.5%), lack of knowledge and preparation skills (38.5%), and confusion surrounding health benefits (6.3%). There is further confusion surrounding the nutrition of frozen vs. fresh vegetables. Finally, respondents were concerned about pesticide residue on imported produce (63.4%). Originality: Although evidence that fruits and vegetables can mitigate disease and that promotion of fruit and vegetable consumption has been a key policy area for the Canadian government, consumers still fail to integrate sufficient fruits and vegetables into their diets. To our knowledge, this is the only study probing consumers on their fresh produce intake in the Canadian context. Public awareness and education about the regular consumption of fruits and vegetables and their nutritional value and health-promoting benefits can increase consumption in many Canadian regions and demographics.
目的:富含水果和蔬菜的饮食对长期健康至关重要。然而,一些地区的水果和蔬菜消费量仍然很低。方法:这项探索性定量研究使用了一种基于网络的调查工具来调查加拿大消费者消费的可能性。对在该国居住12个月或以上、18岁或以上的加拿大人进行了调查。我们注意从加拿大所有地区获取具有代表性的样本。调查结果:农产品消费的障碍包括成本(39.5%)、缺乏知识和准备技能(38.5%)以及对健康益处的困惑(6.3%)。冷冻蔬菜与新鲜蔬菜的营养问题还存在进一步的困惑。最后,受访者对进口农产品的农药残留表示担忧(63.4%)。原创:尽管有证据表明水果和蔬菜可以减轻疾病,促进水果和蔬菜消费一直是加拿大政府的一个关键政策领域,但消费者仍然未能将充足的水果和蔬菜融入他们的饮食中。据我们所知,这是唯一一项在加拿大背景下调查消费者新鲜农产品摄入量的研究。公众对水果和蔬菜的定期消费及其营养价值和促进健康的益处的认识和教育可以增加加拿大许多地区和人口的消费。
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引用次数: 0
Diet Quality, Nutritional Adequacy and Anthropometric Status among Indigenous Women of Reproductive Age Group (15-49 Years) in India: A Narrative Review. 印度育龄期(15-49 岁)土著妇女的饮食质量、营养充足性和人体测量状况:叙述性综述》。
Pub Date : 2022-12-22 DOI: 10.3390/dietetics2010001
Ridhima Kapoor, Manisha Sabharwal, Suparna Ghosh-Jerath

In India, indigenous communities are nutritionally vulnerable, with indigenous women suffering the greater burden. Studies and surveys have reported poor nutritional outcomes among indigenous women in India, yet systematic documentation of community-specific nutrition data is lacking. We conducted a narrative review of 42 studies to summarise the nutritional profile of indigenous women of India, with details on their food and nutrient intakes, dietary diversity, traditional food consumption and anthropometric status. Percentage deficits were observed in intake of pulses, green leafy vegetables, fruits, vegetables, flesh foods and dairy products when compared with recommended dietary intakes for moderately active Indian women. Indices of diet quality in indigenous women were documented in limited studies, which revealed poor dietary diversity as well as low consumption of diverse traditional foods. A high risk of nutritional inadequacy was reported in all communities, especially for iron, calcium, and vitamin A. Prevalence of chronic energy deficiency was high in most communities, with dual burden of malnutrition in indigenous women of north-eastern region. Findings from this review can thus help guide future research and provide valuable insights for policymakers and program implementers on potential interventions for addressing specific nutritional issues among indigenous women of India.

在印度,土著社区在营养方面非常脆弱,土著妇女承受着更大的负担。有研究和调查报告称,印度原住民妇女的营养状况很差,但却缺乏对特定社区营养数据的系统记录。我们对 42 项研究进行了叙述性回顾,总结了印度原住民妇女的营养状况,详细介绍了她们的食物和营养素摄入量、膳食多样性、传统食物消费和人体测量状况。与适度活跃的印度妇女的推荐膳食摄入量相比,豆类、绿叶蔬菜、水果、蔬菜、肉类食品和乳制品的摄入量存在一定比例的不足。有限的研究记录了土著妇女的膳食质量指标,这些研究显示,土著妇女的膳食多样性较差,对各种传统食物的摄入量较低。据报告,在所有社区,营养不足的风险都很高,尤其是铁、钙和维生素 A。在大多数社区,慢性能量缺乏症的发病率都很高,东北部地区的土著妇女承受着营养不良的双重负担。因此,本综述的研究结果有助于指导今后的研究,并为决策者和计划实施者提供宝贵的见解,帮助他们了解解决印度土著妇女特定营养问题的潜在干预措施。
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引用次数: 0
Characteristics of Dietary Intake in Relation to the Consumption of Home-Produced Foods among Farm Women in Two Rural Areas of Kenya: A Preliminary Study 肯尼亚两个农村地区农村妇女的膳食摄入特征与家庭生产食品消费的关系:一项初步研究
Pub Date : 2022-12-07 DOI: 10.3390/dietetics1030021
Madoka Kishino, Miru Hirose, A. Hida, Yuki Tada, K. Ishikawa-Takata, Kenta Hara, Kenji Irie, P. Maundu, Y. Morimoto
The present study aimed to clarify the differences in nutritional intake in relation to the consumption of local food products and dietary patterns between two rural Kenyan regions, Kitui and Vihiga, where different ethnic groups live in different agro-ecological zones. A participant observation study with weighted dietary records was conducted in August 2019. Enumerators stayed in each targeted household for approximately one week and measured the ingredients and dishes. We compared the dietary intake of farm women in charge of meal preparation (n = 21) between the two regions and examined the contribution of each dish to the intake and the degree of home production for each food item. The results showed no difference in energy intake, but vitamin B2, B12, and C intakes were significantly higher in Vihiga, influenced by their consuming small fish and a variety of homegrown leafy vegetables. The people in Kitui consumed large quantities of homegrown pigeon peas, largely contributing to their nutritional intake. Dietary patterns were similar; common staple foods and tea with sugar accounted for about 40% of energy and protein intakes and fruit consumption was low. There was no difference in foods purchased frequently. These results suggested that promoting locally available fruits and vegetables would contribute to a sustainable supply of adequate micronutrients. Further studies are required to develop strategies to promote healthy dietary habits and improve health status.
本研究旨在阐明肯尼亚基图伊和维希加两个农村地区的营养摄入量与当地食品消费和饮食模式之间的差异,这两个地区的不同民族生活在不同的农业生态区。2019年8月进行了一项具有加权饮食记录的参与者观察研究。统计员在每个目标家庭待了大约一周,并测量了食材和菜肴。我们比较了两个地区负责膳食准备的农场妇女(n=21)的饮食摄入量,并检查了每道菜对摄入量的贡献以及每种食物的家庭生产程度。结果显示,能量摄入没有差异,但维希人的维生素B2、B12和C摄入量明显较高,这是受他们食用小型鱼类和各种自制叶菜的影响。基图伊的人们食用了大量自产的鸽子豌豆,这在很大程度上促进了他们的营养摄入。饮食模式相似;常见主食和含糖茶约占能量和蛋白质摄入量的40%,水果消费量较低。经常购买的食物没有差异。这些结果表明,推广当地可获得的水果和蔬菜将有助于可持续供应充足的微量营养素。需要进一步的研究来制定促进健康饮食习惯和改善健康状况的策略。
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引用次数: 0
Supplementation with Crocus sativus L. (Saffron) against Placebo in Multiple Sclerosis: A Systematic Review and Synthesis without Meta-Analysis of Randomized Controlled Trials 藏红花对多发性硬化症安慰剂的补充治疗:一项无荟萃分析的随机对照试验的系统综述和综合
Pub Date : 2022-12-01 DOI: 10.3390/dietetics1030020
M. Grammatikopoulou, S. Tsiogkas, K. Gkiouras, A. Gioxari, E. Daskalou, M. Maraki, E. Dardiotis, D. Bogdanos
Due to its anti-inflammatory and antioxidant capacity and, by inference, its involvement in the myelin stealth attainment, oral nutrient supplementation (ONS) with saffron has recently been investigated as a complementary treatment in multiple sclerosis (MS). The purpose of the present study was to systematically review the literature for randomized controlled trials (RCTs) comparing saffron supplementation to placebo, or other interventions, in patients with an MS diagnosis. PubMed, CENTRAL, and clinicaltrials.gov were searched for relevant completed or ongoing RCTs. The Cochrane’s RoB tool 2.0 was used, and a qualitative synthesis without meta-analysis (SWiM) was performed. In total, five parallel, double-, or triple-blind RCTs were identified, fulfilling the study’s criteria, and were included in the SWiM. Intervention duration ranged from four weeks to a year. The summary RoB revealed some concerns, or even high risk for overall bias. The included RCTs failed to report particularities of their interventions (exact composition, active compound, safety assays, etc.) and adverse events. The SWiM revealed that according to the results of single trials, inflammation markers (TNF-a and IL-17) were reduced, and MS-specific biomarkers (MMP-9 and TIMP-1) and cognition were improved after saffron ONS, although definite conclusions regarding saffron efficacy with regard to these outcomes cannot be drawn. Two RCTs reported improvement in the redox status of patients receiving saffron, whereas, with regard to depression, the findings were conflicting. Overall, ONS with saffron compounds may prove beneficial in improving antioxidant defense and oxidative stress in patients with MS; however, the evidence appears scattered, heterogenous, and inadequate in terms of making any suggestions regarding the direction of effect of other outcomes. Trials of better design and MS-specific outcomes are required.
由于其抗炎和抗氧化能力,以及推测其参与髓鞘隐形实现,藏红花口服营养补充剂(ONS)最近被研究为多发性硬化症(MS)的补充治疗方法。本研究的目的是系统地回顾随机对照试验(RCT)的文献,将藏红花补充剂与安慰剂或其他干预措施在MS诊断患者中进行比较。PubMed、CENTRAL和clinicaltrials.gov搜索相关的已完成或正在进行的随机对照试验。使用Cochrane的RoB工具2.0,并进行无荟萃分析的定性综合(SWiM)。总共确定了五项平行、双盲或三盲随机对照试验,符合研究标准,并纳入SWiM。干预时间从四周到一年不等。RoB的总结揭示了一些担忧,甚至是总体偏倚的高风险。纳入的随机对照试验未能报告其干预措施的特殊性(确切成分、活性化合物、安全性测定等)和不良事件。SWiM显示,根据单一试验的结果,藏红花ONS后,炎症标志物(TNF-a和IL-17)减少,MS特异性生物标志物(MMP-9和TIMP-1)和认知能力得到改善,尽管无法得出关于藏红花对这些结果的疗效的确切结论。两项随机对照试验报告了接受藏红花治疗的患者氧化还原状态的改善,而在抑郁症方面,研究结果相互矛盾。总的来说,含有藏红花化合物的ONS可能对改善MS患者的抗氧化防御和氧化应激有益;然而,在对其他结果的影响方向提出任何建议方面,证据似乎是分散的、异质的和不充分的。需要更好的设计和MS特异性结果的试验。
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引用次数: 0
Short-Term Combined Intake of Vitamin B2 and Vitamin E Decreases Plasma Homocysteine Concentrations in Female Track Athletes 短期联合摄入维生素B2和维生素E可降低女田径运动员血浆同型半胱氨酸浓度
Pub Date : 2022-11-22 DOI: 10.3390/dietetics1030019
Akiho Shinagawa, Naho Serizawa, Tomoki Yamazaki, A. Minematsu, Y. Miyakoshi, T. Yano, M. Ota
Female athletes who endure physical strain on the same bone area are prone to stress fractures. Preventing these improves their quality of life. Blood vitamin B2 (V.B2) and E (V.E) levels influence blood homocysteine (Hcy) levels, which, when elevated, increase the risk of stress fractures. We aimed to determine the effects of V.B2 and V.E supplementation on plasma Hcy concentrations in these athletes carrying the C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR). This study is a before–after study in 16 female athletes. It was divided into three intervention periods of V.B2 (28 mg/day), V.E (60 mg/day), and V.B2 + V.E intake, and each period was 14 days. Blood samples were collected before and after each period, and plasma Hcy concentration and each blood vitamin concentration were measured. Plasma Hcy concentration significantly decreased in all periods, but the maximum lowering effect was obtained when V.B2 and V.E were used in combination. The administration of V.B2 might have lowered the plasma Hcy level by maximizing the catalytic activity of MTHFR; V.E might have suppressed cell oxidation, increasing the efficiency of folate in lowering the plasma Hcy level. We propose the combined intake of V.B2 and V.E as effective nutrients to reduce plasma Hcy concentrations in female athletes with MTHFR polymorphisms.
在同一骨骼区域承受身体压力的女运动员容易发生应力性骨折。预防这些疾病可以提高他们的生活质量。血液中的维生素B2(V.B2)和E(V.E)水平会影响血液中的同型半胱氨酸(Hcy)水平,当其升高时,会增加应力性骨折的风险。我们旨在确定V.B2和V.E对这些携带亚甲基四氢叶酸还原酶(MTHFR)C677T多态性的运动员血浆Hcy浓度的影响。这项研究是对16名女运动员进行的前后研究。将其分为三个干预期,即V.B2(28 mg/天)、V.E(60 mg/日)和V.B2+V.E摄入,每个干预期为14天。在每个周期前后采集血样,测量血浆Hcy浓度和每种血液维生素浓度。血浆Hcy浓度在所有时期都显著降低,但当V.B2和V.E联合使用时,降低效果最大。V.B2的给药可能通过使MTHFR的催化活性最大化而降低了血浆Hcy水平;V.E可能抑制了细胞氧化,提高了叶酸降低血浆Hcy水平的效率。我们建议联合摄入V.B2和V.E作为有效营养素,以降低MTHFR多态性女性运动员的血浆Hcy浓度。
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引用次数: 0
Defining the Practice of Dietitians in Malaysia Using the Nutrition Care Process in Patients with Type 2 Diabetes Mellitus 定义马来西亚营养师在2型糖尿病患者营养护理过程中的实践
Pub Date : 2022-11-10 DOI: 10.3390/dietetics1030018
Jamilah Abd Jamil, E. Myers, W. C. S. Swee
(1) Background: The quality of dietetic care is crucial to improve patient outcomes. The aim of this study was to measure the current practices regarding the provision of nutrition care in type 2 diabetes mellitus (T2DM) among dietitians in Malaysia. (2) Methods: A 49-item online survey was distributed via Malaysian Dietitians’ Association and Ministry of Health Malaysia social media platforms. Self-reported dietetic practices in the management of T2DM were evaluated against practice guidelines. (3) Results: A total of 173 dietitians completed the survey, with a response rate of 62%. Three-quarters of dietitians in the public sector consulted patients within two to three weeks or more than four weeks versus less than two weeks (86.3%) among private dietitians (p-value < 0.001). More than 95% of private dietitians spent 31–60 min or more than 60 min on new cases versus 71% among public dietitians (p-value < 0.001). Group counseling was only practiced among public dietitians (36.0%). Different practice settings led to the current findings. A limited use of behavioral counseling theories and strategies was observed among dietitians from both sectors. Limited adherence to nutrition-related recommendations (62.8%) and lack of readiness for diet/lifestyle changes (45.5%) were the key challenges faced by dietitians when managing T2DM. (4) Conclusions: The survey indicates that there is a need for the development of comprehensive training to increase the utilization of behavioral counselling. Practice setting is an element to consider when designing training.
(1)背景:饮食护理质量对改善患者预后至关重要。本研究的目的是衡量目前马来西亚营养师对2型糖尿病(T2DM)提供营养护理的做法。(2)方法:通过马来西亚营养师协会和马来西亚卫生部社交媒体平台进行49项在线调查。根据实践指南对T2DM管理中自我报告的饮食习惯进行评估。(3)结果:共有173名营养师完成调查,回复率为62%。公立部门四分之三的营养师在两到三周或四周以上的时间内咨询患者,而私立营养师不到两周(86.3%)(p值< 0.001)。超过95%的私人营养师在新病例上花费31-60分钟或超过60分钟,而公共营养师为71% (p值< 0.001)。团体咨询只在公共营养师中进行(36.0%)。不同的实践环境导致了目前的发现。在这两个部门的营养师中观察到行为咨询理论和策略的有限使用。对营养相关建议的遵守有限(62.8%)和缺乏改变饮食/生活方式的准备(45.5%)是营养师在管理T2DM时面临的主要挑战。(4)结论:调查表明,有必要开展综合培训,以提高行为咨询的使用率。练习环境是设计训练时要考虑的一个因素。
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引用次数: 0
A Mechanistic Overview on Impact of Dietary Fibres on Gut Microbiota and Its Association with Colon Cancer 膳食纤维对肠道微生物群影响及其与结肠癌关系的机理综述
Pub Date : 2022-11-02 DOI: 10.3390/dietetics1030017
Vasudev Biswas, Asma Praveen, Arya Lakshmi Marisetti, Ajay Sharma, Vijender Kumar, S. Sahu, Devesh Tewari
Colorectal cancer (CRC) is an abnormal growth that occurs in the rectum or rectal portion. In 2020, an anticipated 104,610 new cases of colon illness and 43,340 new cases of rectal abnormal growth were expected in the United States. Red and processed meat, body bloatedness, belly fatness, and binge drinking expands the occurrence of colorectal disease. Dietary fibres contribute to faecal bulking, but they are break down by gut bacteria and produce metabolites such as short-chain fatty acids (SCFAs). SCFAs are chemical compounds that are mostly made up of acetate, propionate, and butyrate. Acetate and butyrate help to control mucus production and discharge, and thus, protect the gut mucosa. Reduced mucus secretion/increased bacterial catabolism, and fermentation of amino acids resulted in an increase of potentially detrimental metabolites such as branched-chain fatty acids, ammonia, amines, and N-nitroso complex components. Vital roles of fibres include reduction in the time that carcinogens encounter the intestinal lumen and promotion of healthy gut microbiota as well as modification of the host metabolism. The present review focuses on a brief introduction to various dietary fibres and specialised metabolites that can possess beneficial effect on CRC, as well as presenting our current, detailed understanding of various dietary fibres along with their potential effects on gut microbiota and its association with the colon cancer. A comprehensive discussion is also included, advocating the dietary fibre-enriched diet.
癌症(CRC)是一种发生在直肠或直肠部分的异常生长。2020年,预计美国将新增104610例结肠疾病病例和43340例直肠异常生长病例。红肉和加工肉、身体腹胀、腹部肥胖和酗酒会增加结直肠疾病的发生。膳食纤维有助于粪便膨胀,但它们会被肠道细菌分解,并产生短链脂肪酸(SCFA)等代谢产物。SCFA是主要由乙酸盐、丙酸盐和丁酸盐组成的化合物。醋酸盐和丁酸盐有助于控制粘液的产生和排出,从而保护肠道黏膜。粘液分泌减少/细菌分解代谢增加,氨基酸发酵导致潜在有害代谢产物增加,如支链脂肪酸、氨、胺和N-亚硝基复合物成分。纤维的重要作用包括减少致癌物质进入肠腔的时间、促进健康的肠道微生物群以及改变宿主代谢。本综述重点简要介绍了可对CRC产生有益影响的各种膳食纤维和特殊代谢产物,并介绍了我们目前对各种膳食纤维及其对肠道微生物群的潜在影响及其与癌症的关系的详细了解。还包括一个全面的讨论,倡导富含膳食纤维的饮食。
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引用次数: 5
Pre-Conceptual Guidelines for Men: A Review of Male Infertility Experience, including Nutrition and Lifestyle Factors 男性孕前指南:男性不育经验综述,包括营养和生活方式因素
Pub Date : 2022-10-21 DOI: 10.3390/dietetics1030016
J. Bold, David Swinburne
Male fertility is declining and affects approximately one in seven couples. Reasons for this are multi-factorial and the subject of on-going research, though environmental contaminants (such xenoestrogens) are believed to be contributory factors. Semen parameters can be improved through a healthy diet and nutritional supplementation has also been shown to improve semen parameters, clinical pregnancy and live birth rates significantly. Despite this, in medical care dietary modification beyond alcohol reduction is rarely recommended. The aim of this review was to consider the psychosocial impacts of infertility in males whilst assessing other nutritional and lifestyle interventions that can be used in personalized nutrition care. More tailored nutrition care needs to consider this and the taboo surrounding the male infertility experience. A systematic approach was used. Three electronic databases (CINAHL, Medline and Academic Search Complete) were searched using predetermined Boolean search terms and identified 125 papers for review. Hand searches were undertaken to ensure recent evidence was included. Duplicates were removed and predefined inclusion and exclusion criteria were applied. Narrative synthesis was used for review and to develop preconceptual guidelines. Review data indicates dietary modification or supplementation with antioxidants such as vitamin C, vitamin E, coenzyme Q10, selenium, carnitine and zinc have been shown to improve markers of male fertility and reduce markers of seminal oxidative damage. Also, a Mediterranean style diet is also associated with higher quality sperm counts. Weight loss is beneficial in terms of normalizing endocrine profiles but at present it is not possible to determine if this is the effect of weight loss alone, or the combined effect of weight loss alongside other dietary improvement. Further research is therefore needed to understand the role of the many potential confounding factors. Despite this, infertility is emotionally challenging for men and nutrition, and personalised nutrition and lifestyle therapies have potential to support men trying to conceive. Pre-conceptual nutrition and lifestyle guidelines for men have been developed from this review and the use should be considered as the basis for more tailored nutrition care in practice.
男性生育率正在下降,大约每七对夫妇中就有一对受到影响。造成这种情况的原因是多因素的,也是正在进行的研究的主题,尽管环境污染物(如外源性雌激素)被认为是促成因素。通过健康饮食可以改善精液参数,营养补充也被证明可以显著改善精液参数、临床妊娠率和活产率。尽管如此,在医疗保健中,除了减少饮酒之外,很少建议进行饮食调整。本综述的目的是考虑男性不孕不育的心理社会影响,同时评估可用于个性化营养护理的其他营养和生活方式干预措施。更有针对性的营养护理需要考虑到这一点以及围绕男性不孕经历的禁忌。采用了系统的方法。使用预先确定的布尔搜索词搜索三个电子数据库(CINAHL、Medline和Academic Search Complete),并确定125篇论文供审查。进行了手部搜查,以确保包括最近的证据。删除了重复项,并应用了预定义的纳入和排除标准。叙述综合被用于审查和制定先入为主的指导方针。综述数据表明,改变饮食或补充抗氧化剂,如维生素C、维生素E、辅酶Q10、硒、肉碱和锌,已被证明可以改善男性生育能力的标志物,减少精液氧化损伤的标志物。此外,地中海式饮食也与更高质量的精子计数有关。减肥对内分泌状况的正常化是有益的,但目前还无法确定这是单独减肥的影响,还是减肥与其他饮食改善的综合影响。因此,需要进一步的研究来了解许多潜在混杂因素的作用。尽管如此,不孕不育对男性和营养来说是一个情感挑战,个性化的营养和生活方式疗法有可能支持试图怀孕的男性。这篇综述为男性制定了概念前营养和生活方式指南,应将其使用视为实践中更具针对性的营养护理的基础。
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引用次数: 7
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Dietetics (Basel, Switzerland)
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