首页 > 最新文献

Dietetics (Basel, Switzerland)最新文献

英文 中文
A Mechanistic Overview on Impact of Dietary Fibres on Gut Microbiota and Its Association with Colon Cancer 膳食纤维对肠道微生物群影响及其与结肠癌关系的机理综述
Pub Date : 2022-11-02 DOI: 10.3390/dietetics1030017
Vasudev Biswas, Asma Praveen, Arya Lakshmi Marisetti, Ajay Sharma, Vijender Kumar, S. Sahu, Devesh Tewari
Colorectal cancer (CRC) is an abnormal growth that occurs in the rectum or rectal portion. In 2020, an anticipated 104,610 new cases of colon illness and 43,340 new cases of rectal abnormal growth were expected in the United States. Red and processed meat, body bloatedness, belly fatness, and binge drinking expands the occurrence of colorectal disease. Dietary fibres contribute to faecal bulking, but they are break down by gut bacteria and produce metabolites such as short-chain fatty acids (SCFAs). SCFAs are chemical compounds that are mostly made up of acetate, propionate, and butyrate. Acetate and butyrate help to control mucus production and discharge, and thus, protect the gut mucosa. Reduced mucus secretion/increased bacterial catabolism, and fermentation of amino acids resulted in an increase of potentially detrimental metabolites such as branched-chain fatty acids, ammonia, amines, and N-nitroso complex components. Vital roles of fibres include reduction in the time that carcinogens encounter the intestinal lumen and promotion of healthy gut microbiota as well as modification of the host metabolism. The present review focuses on a brief introduction to various dietary fibres and specialised metabolites that can possess beneficial effect on CRC, as well as presenting our current, detailed understanding of various dietary fibres along with their potential effects on gut microbiota and its association with the colon cancer. A comprehensive discussion is also included, advocating the dietary fibre-enriched diet.
癌症(CRC)是一种发生在直肠或直肠部分的异常生长。2020年,预计美国将新增104610例结肠疾病病例和43340例直肠异常生长病例。红肉和加工肉、身体腹胀、腹部肥胖和酗酒会增加结直肠疾病的发生。膳食纤维有助于粪便膨胀,但它们会被肠道细菌分解,并产生短链脂肪酸(SCFA)等代谢产物。SCFA是主要由乙酸盐、丙酸盐和丁酸盐组成的化合物。醋酸盐和丁酸盐有助于控制粘液的产生和排出,从而保护肠道黏膜。粘液分泌减少/细菌分解代谢增加,氨基酸发酵导致潜在有害代谢产物增加,如支链脂肪酸、氨、胺和N-亚硝基复合物成分。纤维的重要作用包括减少致癌物质进入肠腔的时间、促进健康的肠道微生物群以及改变宿主代谢。本综述重点简要介绍了可对CRC产生有益影响的各种膳食纤维和特殊代谢产物,并介绍了我们目前对各种膳食纤维及其对肠道微生物群的潜在影响及其与癌症的关系的详细了解。还包括一个全面的讨论,倡导富含膳食纤维的饮食。
{"title":"A Mechanistic Overview on Impact of Dietary Fibres on Gut Microbiota and Its Association with Colon Cancer","authors":"Vasudev Biswas, Asma Praveen, Arya Lakshmi Marisetti, Ajay Sharma, Vijender Kumar, S. Sahu, Devesh Tewari","doi":"10.3390/dietetics1030017","DOIUrl":"https://doi.org/10.3390/dietetics1030017","url":null,"abstract":"Colorectal cancer (CRC) is an abnormal growth that occurs in the rectum or rectal portion. In 2020, an anticipated 104,610 new cases of colon illness and 43,340 new cases of rectal abnormal growth were expected in the United States. Red and processed meat, body bloatedness, belly fatness, and binge drinking expands the occurrence of colorectal disease. Dietary fibres contribute to faecal bulking, but they are break down by gut bacteria and produce metabolites such as short-chain fatty acids (SCFAs). SCFAs are chemical compounds that are mostly made up of acetate, propionate, and butyrate. Acetate and butyrate help to control mucus production and discharge, and thus, protect the gut mucosa. Reduced mucus secretion/increased bacterial catabolism, and fermentation of amino acids resulted in an increase of potentially detrimental metabolites such as branched-chain fatty acids, ammonia, amines, and N-nitroso complex components. Vital roles of fibres include reduction in the time that carcinogens encounter the intestinal lumen and promotion of healthy gut microbiota as well as modification of the host metabolism. The present review focuses on a brief introduction to various dietary fibres and specialised metabolites that can possess beneficial effect on CRC, as well as presenting our current, detailed understanding of various dietary fibres along with their potential effects on gut microbiota and its association with the colon cancer. A comprehensive discussion is also included, advocating the dietary fibre-enriched diet.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45071436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Pre-Conceptual Guidelines for Men: A Review of Male Infertility Experience, including Nutrition and Lifestyle Factors 男性孕前指南:男性不育经验综述,包括营养和生活方式因素
Pub Date : 2022-10-21 DOI: 10.3390/dietetics1030016
J. Bold, David Swinburne
Male fertility is declining and affects approximately one in seven couples. Reasons for this are multi-factorial and the subject of on-going research, though environmental contaminants (such xenoestrogens) are believed to be contributory factors. Semen parameters can be improved through a healthy diet and nutritional supplementation has also been shown to improve semen parameters, clinical pregnancy and live birth rates significantly. Despite this, in medical care dietary modification beyond alcohol reduction is rarely recommended. The aim of this review was to consider the psychosocial impacts of infertility in males whilst assessing other nutritional and lifestyle interventions that can be used in personalized nutrition care. More tailored nutrition care needs to consider this and the taboo surrounding the male infertility experience. A systematic approach was used. Three electronic databases (CINAHL, Medline and Academic Search Complete) were searched using predetermined Boolean search terms and identified 125 papers for review. Hand searches were undertaken to ensure recent evidence was included. Duplicates were removed and predefined inclusion and exclusion criteria were applied. Narrative synthesis was used for review and to develop preconceptual guidelines. Review data indicates dietary modification or supplementation with antioxidants such as vitamin C, vitamin E, coenzyme Q10, selenium, carnitine and zinc have been shown to improve markers of male fertility and reduce markers of seminal oxidative damage. Also, a Mediterranean style diet is also associated with higher quality sperm counts. Weight loss is beneficial in terms of normalizing endocrine profiles but at present it is not possible to determine if this is the effect of weight loss alone, or the combined effect of weight loss alongside other dietary improvement. Further research is therefore needed to understand the role of the many potential confounding factors. Despite this, infertility is emotionally challenging for men and nutrition, and personalised nutrition and lifestyle therapies have potential to support men trying to conceive. Pre-conceptual nutrition and lifestyle guidelines for men have been developed from this review and the use should be considered as the basis for more tailored nutrition care in practice.
男性生育率正在下降,大约每七对夫妇中就有一对受到影响。造成这种情况的原因是多因素的,也是正在进行的研究的主题,尽管环境污染物(如外源性雌激素)被认为是促成因素。通过健康饮食可以改善精液参数,营养补充也被证明可以显著改善精液参数、临床妊娠率和活产率。尽管如此,在医疗保健中,除了减少饮酒之外,很少建议进行饮食调整。本综述的目的是考虑男性不孕不育的心理社会影响,同时评估可用于个性化营养护理的其他营养和生活方式干预措施。更有针对性的营养护理需要考虑到这一点以及围绕男性不孕经历的禁忌。采用了系统的方法。使用预先确定的布尔搜索词搜索三个电子数据库(CINAHL、Medline和Academic Search Complete),并确定125篇论文供审查。进行了手部搜查,以确保包括最近的证据。删除了重复项,并应用了预定义的纳入和排除标准。叙述综合被用于审查和制定先入为主的指导方针。综述数据表明,改变饮食或补充抗氧化剂,如维生素C、维生素E、辅酶Q10、硒、肉碱和锌,已被证明可以改善男性生育能力的标志物,减少精液氧化损伤的标志物。此外,地中海式饮食也与更高质量的精子计数有关。减肥对内分泌状况的正常化是有益的,但目前还无法确定这是单独减肥的影响,还是减肥与其他饮食改善的综合影响。因此,需要进一步的研究来了解许多潜在混杂因素的作用。尽管如此,不孕不育对男性和营养来说是一个情感挑战,个性化的营养和生活方式疗法有可能支持试图怀孕的男性。这篇综述为男性制定了概念前营养和生活方式指南,应将其使用视为实践中更具针对性的营养护理的基础。
{"title":"Pre-Conceptual Guidelines for Men: A Review of Male Infertility Experience, including Nutrition and Lifestyle Factors","authors":"J. Bold, David Swinburne","doi":"10.3390/dietetics1030016","DOIUrl":"https://doi.org/10.3390/dietetics1030016","url":null,"abstract":"Male fertility is declining and affects approximately one in seven couples. Reasons for this are multi-factorial and the subject of on-going research, though environmental contaminants (such xenoestrogens) are believed to be contributory factors. Semen parameters can be improved through a healthy diet and nutritional supplementation has also been shown to improve semen parameters, clinical pregnancy and live birth rates significantly. Despite this, in medical care dietary modification beyond alcohol reduction is rarely recommended. The aim of this review was to consider the psychosocial impacts of infertility in males whilst assessing other nutritional and lifestyle interventions that can be used in personalized nutrition care. More tailored nutrition care needs to consider this and the taboo surrounding the male infertility experience. A systematic approach was used. Three electronic databases (CINAHL, Medline and Academic Search Complete) were searched using predetermined Boolean search terms and identified 125 papers for review. Hand searches were undertaken to ensure recent evidence was included. Duplicates were removed and predefined inclusion and exclusion criteria were applied. Narrative synthesis was used for review and to develop preconceptual guidelines. Review data indicates dietary modification or supplementation with antioxidants such as vitamin C, vitamin E, coenzyme Q10, selenium, carnitine and zinc have been shown to improve markers of male fertility and reduce markers of seminal oxidative damage. Also, a Mediterranean style diet is also associated with higher quality sperm counts. Weight loss is beneficial in terms of normalizing endocrine profiles but at present it is not possible to determine if this is the effect of weight loss alone, or the combined effect of weight loss alongside other dietary improvement. Further research is therefore needed to understand the role of the many potential confounding factors. Despite this, infertility is emotionally challenging for men and nutrition, and personalised nutrition and lifestyle therapies have potential to support men trying to conceive. Pre-conceptual nutrition and lifestyle guidelines for men have been developed from this review and the use should be considered as the basis for more tailored nutrition care in practice.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47742219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Identifying Consumer Mindsets Related to Sugars Consumption in Canadian Adults 识别与加拿大成年人糖消费相关的消费者心态
Pub Date : 2022-10-03 DOI: 10.3390/dietetics1030014
K. Viana, S. Davidov, Olivia Morello, Diana Mariela Puga Arguello, H. Moskowitz, N. Bellissimo
Little is known about the attitudes and perceptions towards dietary sugars in Canadian adults. The objective of this study was to use rule-developing experimentation (RDE) to identify consumer mindsets related to dietary sugars in 18–50-year-old Canadians. Following an isomorphic permuted experimental design, participants (n = 269) each rated a unique set of 24 scenarios, each consisting of a distinct mixture of two to four messages about dietary sugars on a 5-point scale. A regression model was created for each respondent, identifying the value that each respondent attributed to each of the 16 messages. K-means clustering revealed three distinct mindset groups as follows: “Sugars Beliefs” (MS1), “Trend Analysts” (MS2), and “Health Seekers” (MS3). In conclusion, this study found that RDE is a useful methodological approach for evaluating how consumers think about dietary sugars and revealed mindset-specific messages that matter most to people who differ in their attitudes toward sugars.
对加拿大成年人对膳食糖的态度和看法知之甚少。本研究的目的是使用规则发展实验(RDE)来确定18-50岁加拿大人与饮食糖相关的消费者心态。根据同构排列的实验设计,参与者(n=269)每个人都对一组独特的24个场景进行了评分,每个场景由两到四个关于饮食糖的不同信息组成,分为5分制。为每个受访者创建了一个回归模型,确定了每个受访者对16条信息中每条信息的价值。K-means聚类揭示了三个不同的心态群体:“糖的信仰”(MS1)、“趋势分析师”(MS2)和“健康寻求者”(MS3)。总之,这项研究发现,RDE是一种有用的方法论方法,可以评估消费者对膳食糖的看法,并揭示对糖态度不同的人来说最重要的特定心态信息。
{"title":"Identifying Consumer Mindsets Related to Sugars Consumption in Canadian Adults","authors":"K. Viana, S. Davidov, Olivia Morello, Diana Mariela Puga Arguello, H. Moskowitz, N. Bellissimo","doi":"10.3390/dietetics1030014","DOIUrl":"https://doi.org/10.3390/dietetics1030014","url":null,"abstract":"Little is known about the attitudes and perceptions towards dietary sugars in Canadian adults. The objective of this study was to use rule-developing experimentation (RDE) to identify consumer mindsets related to dietary sugars in 18–50-year-old Canadians. Following an isomorphic permuted experimental design, participants (n = 269) each rated a unique set of 24 scenarios, each consisting of a distinct mixture of two to four messages about dietary sugars on a 5-point scale. A regression model was created for each respondent, identifying the value that each respondent attributed to each of the 16 messages. K-means clustering revealed three distinct mindset groups as follows: “Sugars Beliefs” (MS1), “Trend Analysts” (MS2), and “Health Seekers” (MS3). In conclusion, this study found that RDE is a useful methodological approach for evaluating how consumers think about dietary sugars and revealed mindset-specific messages that matter most to people who differ in their attitudes toward sugars.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41820294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Content, Quality and Accuracy of Online Nutrition Resources for the Prevention and Treatment of Dementia: A Review of Online Content 预防和治疗痴呆症的在线营养资源的内容、质量和准确性:在线内容综述
Pub Date : 2022-10-03 DOI: 10.3390/dietetics1030015
Justine Lee, Julie Nguyen, F. O’Leary
(1) Background: The internet is a popular information source; however, research evaluating online nutrition-related dementia information is limited. This review characterised content, quality, and accuracy of online dementia-specific nutrition resources for dementia prevention and treatment. (2) Methods: JBI methodology for scoping reviews guided the study. Searches used Google search engine with terms related to dementia and nutrition. Webpages from government, organisational and commercial sources were included; blogs, social media and media sources were excluded. DISCERN tool evaluated content quality; accuracy was assessed against ESPEN and WHO guidelines. Differences in mean DISCERN scores were calculated using ANOVA. (3) Results: 105 webpages from eight countries were included. Webpages were mainly from organisational sources (n = 65) and covered nutrition-related prevention (n = 52) including diet–disease relationships (n = 81). Fewer webpages provided information on dementia related eating issues. The total mean DISCERN score (SD) was 50 ± 8, indicating overall good quality. All government webpages provided accurate information. Commercial webpages had some inaccuracy (ESPEN: 3% mixed, 3% inaccurate; WHO: 3% mixed, 3% inaccurate). (4) Conclusions: Information was of reasonable quality and mostly accurate. Further information on dementia-related eating issues is needed. Future research could address readability, understandability and actionability and examine other sources, such as social media, blogs or forums.
(1)背景:互联网是一种流行的信息来源;然而,评估在线营养相关痴呆症信息的研究是有限的。这篇综述描述了用于痴呆症预防和治疗的在线痴呆症特异性营养资源的内容、质量和准确性。(2)方法:采用JBI方法进行范围评价。使用谷歌搜索引擎搜索与痴呆和营养相关的词条。包括政府、机构和商业来源的网页;博客、社交媒体和媒体来源被排除在外。DISCERN工具评估内容质量;根据ESPEN和世卫组织指南评估准确性。使用方差分析计算平均DISCERN评分的差异。(3)结果:共纳入了来自8个国家的105个网页。网页主要来自组织来源(n = 65),涵盖营养相关预防(n = 52),包括饮食与疾病的关系(n = 81)。提供痴呆症相关饮食问题信息的网页较少。总平均DISCERN评分(SD)为50±8分,总体质量良好。所有政府网页均提供准确的资讯。商业网页有一些不准确(ESPEN: 3%混合,3%不准确;世卫组织:3%混合,3%不准确)。(4)结论:信息质量合理,基本准确。需要有关痴呆症相关饮食问题的进一步信息。未来的研究可以解决可读性,可理解性和可操作性,并检查其他来源,如社交媒体,博客或论坛。
{"title":"Content, Quality and Accuracy of Online Nutrition Resources for the Prevention and Treatment of Dementia: A Review of Online Content","authors":"Justine Lee, Julie Nguyen, F. O’Leary","doi":"10.3390/dietetics1030015","DOIUrl":"https://doi.org/10.3390/dietetics1030015","url":null,"abstract":"(1) Background: The internet is a popular information source; however, research evaluating online nutrition-related dementia information is limited. This review characterised content, quality, and accuracy of online dementia-specific nutrition resources for dementia prevention and treatment. (2) Methods: JBI methodology for scoping reviews guided the study. Searches used Google search engine with terms related to dementia and nutrition. Webpages from government, organisational and commercial sources were included; blogs, social media and media sources were excluded. DISCERN tool evaluated content quality; accuracy was assessed against ESPEN and WHO guidelines. Differences in mean DISCERN scores were calculated using ANOVA. (3) Results: 105 webpages from eight countries were included. Webpages were mainly from organisational sources (n = 65) and covered nutrition-related prevention (n = 52) including diet–disease relationships (n = 81). Fewer webpages provided information on dementia related eating issues. The total mean DISCERN score (SD) was 50 ± 8, indicating overall good quality. All government webpages provided accurate information. Commercial webpages had some inaccuracy (ESPEN: 3% mixed, 3% inaccurate; WHO: 3% mixed, 3% inaccurate). (4) Conclusions: Information was of reasonable quality and mostly accurate. Further information on dementia-related eating issues is needed. Future research could address readability, understandability and actionability and examine other sources, such as social media, blogs or forums.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47717073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Nutritional Knowledge of the Mediterranean Diet Is Associated with Positive Attitudes and Adherence in a Non-Mediterranean Multi-Ethnic Society 在非地中海多民族社会中,地中海饮食的营养知识与积极态度和坚持有关
Pub Date : 2022-09-13 DOI: 10.3390/dietetics1020013
Yasmin Aridi, Jacqueline L. Walker, E. Roura, O. Wright
The aim of this cross-sectional study was to understand how the public in a non-Mediterranean multi-ethnic society perceived the Mediterranean dietary pattern (MDP) and its general health benefits. A total of 373 participants took part in this study. Most of the sample were young adults, females and had been living in Australia for over 10 years. Knowledge of the MDP score, attitudes towards the MDP score and an adherence to the MPD score were measured. Normality of variables was tested. Simple linear regression and Chi-squared tests were conducted to examine associations. ANOVA tests were used to report participants’ demographics across various attitudes scores. Less than half of participants were aware of the MDP guidelines, food choices and health benefits. As for adherence to the MDP, 20% of the sample were found to have high adherence to the MDP. Results also showed that participants with high knowledge about the MDP were twice more likely to have higher MDP adherence rates, OR 95% CI = 2.3 (1.3, 4.0), p-value = 0.002. This paper provided new insights about the association between nutritional knowledge and adherence to the MDP in a multi-ethnic non-Mediterranean setting.
这项横断面研究的目的是了解非地中海多民族社会的公众如何看待地中海饮食模式及其对健康的总体益处。共有373名参与者参与了这项研究。大多数样本是年轻人,女性,已经在澳大利亚生活了10多年。测量对MDP评分的了解、对MDP得分的态度以及对MPD评分的坚持程度。检验了变量的正态性。采用简单线性回归和卡方检验来检验相关性。方差分析测试用于报告参与者在不同态度得分下的人口统计数据。不到一半的参与者了解MDP指南、食物选择和健康益处。关于对MDP的粘附性,发现20%的样本对MDP具有高粘附性。结果还显示,对MDP了解程度高的参与者的MDP依从率是其他参与者的两倍,OR 95%CI=2.3(1.3,4.0),p值=0.002。这篇论文为多民族非地中海环境中营养知识与坚持MDP之间的关系提供了新的见解。
{"title":"Nutritional Knowledge of the Mediterranean Diet Is Associated with Positive Attitudes and Adherence in a Non-Mediterranean Multi-Ethnic Society","authors":"Yasmin Aridi, Jacqueline L. Walker, E. Roura, O. Wright","doi":"10.3390/dietetics1020013","DOIUrl":"https://doi.org/10.3390/dietetics1020013","url":null,"abstract":"The aim of this cross-sectional study was to understand how the public in a non-Mediterranean multi-ethnic society perceived the Mediterranean dietary pattern (MDP) and its general health benefits. A total of 373 participants took part in this study. Most of the sample were young adults, females and had been living in Australia for over 10 years. Knowledge of the MDP score, attitudes towards the MDP score and an adherence to the MPD score were measured. Normality of variables was tested. Simple linear regression and Chi-squared tests were conducted to examine associations. ANOVA tests were used to report participants’ demographics across various attitudes scores. Less than half of participants were aware of the MDP guidelines, food choices and health benefits. As for adherence to the MDP, 20% of the sample were found to have high adherence to the MDP. Results also showed that participants with high knowledge about the MDP were twice more likely to have higher MDP adherence rates, OR 95% CI = 2.3 (1.3, 4.0), p-value = 0.002. This paper provided new insights about the association between nutritional knowledge and adherence to the MDP in a multi-ethnic non-Mediterranean setting.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44811114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical Trials of Vitamin Supplements: Are They Meeting the European Medicines Agency Prompt Dissemination Regulation? 维生素补充剂的临床试验:它们符合欧洲药品管理局的即时传播条例吗?
Pub Date : 2022-09-01 DOI: 10.3390/dietetics1020012
M. Lampropoulou, M. Grammatikopoulou, X. Theodoridis, Savvas Katsaridis, Despoina Bobora, A. Patsatsi, A. Haidich, D. Goulis
Vitamin supplements are over-the-counter medications consumed by the majority of adults. Given that many supplements may be ineffective and/or associated with adverse events, compliance of the registered trials to the European Medicines Agency (EMA) rule for prompt reporting of the results is of crucial importance for consumers’ health. The present retrospective study was designed to evaluate compliance with the European Union (EU) requirement to post the trial results to the EU Clinical Trials Database (EudraCT) and assess the trial characteristics associated with this compliance. Three independent researchers searched the EudraCT for completed trials on vitamin supplements performed on humans. A total of 144 completed trials involving 40,464 participants fulfilled the inclusion criteria. For 45.7% of these, results were due. Trials funded by the industry had approximately quadruple chances of being published, adjusting for their design, masking, comparator, and participant age group. Moreover, trials testing vitamin supplement safety are more likely to report their findings as compared to vitamin efficacy. Many vitamin supplementation trials registered in the EudraCT failed to report their results and adhere to the EMA regulations. Stricter regulations should be imposed concerning trial results reporting to increase transparency and public trust.
维生素补充剂是大多数成年人服用的非处方药。鉴于许多补充剂可能无效和/或与不良事件有关,注册试验遵守欧洲药品管理局(EMA)的规则,及时报告结果对消费者的健康至关重要。本回顾性研究旨在评估是否符合欧盟(EU)的要求,将试验结果发布到欧盟临床试验数据库(EudraCT),并评估与该符合性相关的试验特征。三名独立研究人员在EudraCT上搜索了已完成的人体维生素补充剂试验。共有144项已完成的试验,涉及40464名参与者,符合入选标准。对于其中45.7%的人来说,结果是应该的。由该行业资助的试验发表的几率约为其设计、掩蔽、比较和参与者年龄组的四倍。此外,与维生素功效相比,测试维生素补充剂安全性的试验更有可能报告他们的发现。在欧洲药品监督管理局注册的许多维生素补充剂试验都没有报告结果,也没有遵守欧洲药品管理局的规定。应在审判结果报告方面实施更严格的规定,以提高透明度和公众信任。
{"title":"Clinical Trials of Vitamin Supplements: Are They Meeting the European Medicines Agency Prompt Dissemination Regulation?","authors":"M. Lampropoulou, M. Grammatikopoulou, X. Theodoridis, Savvas Katsaridis, Despoina Bobora, A. Patsatsi, A. Haidich, D. Goulis","doi":"10.3390/dietetics1020012","DOIUrl":"https://doi.org/10.3390/dietetics1020012","url":null,"abstract":"Vitamin supplements are over-the-counter medications consumed by the majority of adults. Given that many supplements may be ineffective and/or associated with adverse events, compliance of the registered trials to the European Medicines Agency (EMA) rule for prompt reporting of the results is of crucial importance for consumers’ health. The present retrospective study was designed to evaluate compliance with the European Union (EU) requirement to post the trial results to the EU Clinical Trials Database (EudraCT) and assess the trial characteristics associated with this compliance. Three independent researchers searched the EudraCT for completed trials on vitamin supplements performed on humans. A total of 144 completed trials involving 40,464 participants fulfilled the inclusion criteria. For 45.7% of these, results were due. Trials funded by the industry had approximately quadruple chances of being published, adjusting for their design, masking, comparator, and participant age group. Moreover, trials testing vitamin supplement safety are more likely to report their findings as compared to vitamin efficacy. Many vitamin supplementation trials registered in the EudraCT failed to report their results and adhere to the EMA regulations. Stricter regulations should be imposed concerning trial results reporting to increase transparency and public trust.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42949836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
High Consumption of Discretionary Beverages in Young Australian Adults Aged 18–30 Years: A Cross-Sectional Study 18-30岁的澳大利亚年轻人随意饮料的高消费:一项横断面研究
Pub Date : 2022-08-18 DOI: 10.3390/dietetics1020011
A. Duncan, A. Rangan, Pui Ying Ho, Virginia Chan, Alyse Davies, Lyndal Wellard-Cole, M. Allman-Farinelli
Despite health advice and campaigns, discretionary beverages remain a source of added sweeteners (sugar and intense sweeteners) and fat in the dietary intakes of many young adults. This study aimed to determine discretionary beverage consumption amongst 18 to 30-year-olds residing in New South Wales, Australia. Data were collected in 2017/2018 during the MYMeals study in which 1044 participants recorded their food and beverage consumption over a three-day period, using the purpose-designed Eat and Track (EaT) app. Discretionary beverages included all water-based and milk-based drinks with added sugar, intense sweeteners or fats and excluded alcoholic beverages. Descriptive statistics were used to analyse the proportion of consumers for different types of beverages, and contribution to overall energy and nutrient intakes. ANCOVA analyses compared the energy and nutrient intakes of consumers and non-consumers, adjusted for gender and age group. Sixty-two percent of participants with complete data (n = 1001) were classified as consumers of discretionary beverages. The most consumed beverages were soft drinks (39.0%) and flavoured tea/coffee (23.1%). The greatest proportion of nutrients contributed by discretionary beverages was total sugars (27.2% of total per consumers). In comparison to non-consumers, consumers of discretionary beverages had higher mean daily intakes of energy (kJ) (8736 versus 7294), and higher percentage energy (%E) from total sugars (16.5 versus 13.3) (p < 0.001) and saturated fat (12.5 versus 12.0) (p < 0.05) but lower protein (18.5 versus 20.5) (p < 0.001). The consumption of non-alcoholic discretionary beverages continues to be a source of significant energy and total sugars among young adults.
尽管有健康建议和运动,但在许多年轻人的饮食摄入中,非必需饮料仍然是添加甜味剂(糖和强效甜味剂)和脂肪的来源。本研究旨在确定居住在澳大利亚新南威尔士州的18至30岁人群的可自由支配饮料消费量。数据收集于2017/2018年MYMeals研究期间,1044名参与者使用专门设计的Eat and Track(Eat)应用程序记录了他们在三天内的食品和饮料消费情况。非必需饮料包括所有添加糖、强效甜味剂或脂肪的水性和乳基饮料,不包括酒精饮料。描述性统计用于分析不同类型饮料的消费者比例,以及对整体能量和营养摄入的贡献。ANCOVA分析比较了消费者和非消费者的能量和营养摄入,并根据性别和年龄组进行了调整。62%拥有完整数据的参与者(n=1001)被归类为非必需饮料的消费者。消费最多的饮料是软饮料(39.0%)和调味茶/咖啡(23.1%)。非必需饮料提供的营养成分比例最大的是总糖(占每位消费者总糖的27.2%)。与非消费者相比,非必需饮料的消费者具有更高的平均每日能量摄入量(kJ)(8736对7294),总糖(16.5比13.3)(p<0.001)和饱和脂肪(12.5比12.0)(p>0.05)的能量百分比(%E)较高,但蛋白质(18.5比20.5)较低(p<001)。非酒精非必需饮料的消费仍然是年轻人能量和总糖的重要来源。
{"title":"High Consumption of Discretionary Beverages in Young Australian Adults Aged 18–30 Years: A Cross-Sectional Study","authors":"A. Duncan, A. Rangan, Pui Ying Ho, Virginia Chan, Alyse Davies, Lyndal Wellard-Cole, M. Allman-Farinelli","doi":"10.3390/dietetics1020011","DOIUrl":"https://doi.org/10.3390/dietetics1020011","url":null,"abstract":"Despite health advice and campaigns, discretionary beverages remain a source of added sweeteners (sugar and intense sweeteners) and fat in the dietary intakes of many young adults. This study aimed to determine discretionary beverage consumption amongst 18 to 30-year-olds residing in New South Wales, Australia. Data were collected in 2017/2018 during the MYMeals study in which 1044 participants recorded their food and beverage consumption over a three-day period, using the purpose-designed Eat and Track (EaT) app. Discretionary beverages included all water-based and milk-based drinks with added sugar, intense sweeteners or fats and excluded alcoholic beverages. Descriptive statistics were used to analyse the proportion of consumers for different types of beverages, and contribution to overall energy and nutrient intakes. ANCOVA analyses compared the energy and nutrient intakes of consumers and non-consumers, adjusted for gender and age group. Sixty-two percent of participants with complete data (n = 1001) were classified as consumers of discretionary beverages. The most consumed beverages were soft drinks (39.0%) and flavoured tea/coffee (23.1%). The greatest proportion of nutrients contributed by discretionary beverages was total sugars (27.2% of total per consumers). In comparison to non-consumers, consumers of discretionary beverages had higher mean daily intakes of energy (kJ) (8736 versus 7294), and higher percentage energy (%E) from total sugars (16.5 versus 13.3) (p < 0.001) and saturated fat (12.5 versus 12.0) (p < 0.05) but lower protein (18.5 versus 20.5) (p < 0.001). The consumption of non-alcoholic discretionary beverages continues to be a source of significant energy and total sugars among young adults.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47361192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dietary Patterns and Blood Biochemical and Metabolic Parameters in an Italian Population: A Cross-Sectional Study 意大利人群的饮食模式和血液生化代谢参数:一项横断面研究
Pub Date : 2022-08-05 DOI: 10.3390/dietetics1020010
Marta Cecchini, Teresa Urbano, D. Lasagni, Tiziana De Luca, M. Malavolti, C. Baraldi, S. Grioni, C. Agnoli, S. Sieri, A. Santachiara, T. Pertinhez, S. Fustinoni, R. Baricchi, M. Vinceti, T. Filippini
Diet has long been identified as a major determinant of cardiovascular and other chronic diseases. In this study, we assess the relation between adherence to different dietary patterns and biochemical and metabolic parameters as well as the 10-year risk of major cardiovascular diseases (CVDs) in a community of blood donors in Northern Italy. We assess their adherence to four dietary patterns, namely, the Dietary Approach to Stop Hypertension (DASH) diet, the Mediterranean diet through the Greek and Italian Mediterranean Indices (GMI and IMI) and the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, using a validated semi-quantitative food frequency questionnaire (FFQ). We then assess their association with blood parameters and the 10-year risk of major CVD using a spline regression model. We found an inverse association between the DASH and MIND diets and total and LDL cholesterol, and triglyceride and HDL cholesterol values for the Mediterranean diets (IMI and GMI). Additionally, according to our sex-stratified analyses, men who have greater adherence to dietary patterns have a decreased risk of major CVD for all patterns. The results suggest that greater adherence to dietary patterns positively influences blood biochemical and metabolic parameters, thus reducing the risk of developing cardiovascular disease and delaying the use of drug treatments.
长期以来,饮食一直被认为是心血管和其他慢性疾病的主要决定因素。在这项研究中,我们评估了意大利北部献血者社区对不同饮食模式、生化和代谢参数的坚持与10年来患主要心血管疾病(CVD)风险之间的关系。我们使用经验证的半定量食物频率问卷(FFQ)评估了他们对四种饮食模式的依从性,即停止高血压的饮食方法(DASH)饮食、通过希腊和意大利地中海指数(GMI和IMI)的地中海饮食以及神经退行性延迟的地中海DASH干预(MIND)饮食。然后,我们使用样条回归模型评估它们与血液参数和10年重大心血管疾病风险的关系。我们发现,DASH和MIND饮食与地中海饮食(IMI和GMI)的总胆固醇和低密度脂蛋白胆固醇、甘油三酯和高密度脂蛋白含量呈负相关。此外,根据我们的性别分层分析,更坚持饮食模式的男性在所有模式下患严重心血管疾病的风险都会降低。研究结果表明,更严格地遵守饮食模式会对血液生化和代谢参数产生积极影响,从而降低患心血管疾病的风险,并推迟药物治疗的使用。
{"title":"Dietary Patterns and Blood Biochemical and Metabolic Parameters in an Italian Population: A Cross-Sectional Study","authors":"Marta Cecchini, Teresa Urbano, D. Lasagni, Tiziana De Luca, M. Malavolti, C. Baraldi, S. Grioni, C. Agnoli, S. Sieri, A. Santachiara, T. Pertinhez, S. Fustinoni, R. Baricchi, M. Vinceti, T. Filippini","doi":"10.3390/dietetics1020010","DOIUrl":"https://doi.org/10.3390/dietetics1020010","url":null,"abstract":"Diet has long been identified as a major determinant of cardiovascular and other chronic diseases. In this study, we assess the relation between adherence to different dietary patterns and biochemical and metabolic parameters as well as the 10-year risk of major cardiovascular diseases (CVDs) in a community of blood donors in Northern Italy. We assess their adherence to four dietary patterns, namely, the Dietary Approach to Stop Hypertension (DASH) diet, the Mediterranean diet through the Greek and Italian Mediterranean Indices (GMI and IMI) and the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, using a validated semi-quantitative food frequency questionnaire (FFQ). We then assess their association with blood parameters and the 10-year risk of major CVD using a spline regression model. We found an inverse association between the DASH and MIND diets and total and LDL cholesterol, and triglyceride and HDL cholesterol values for the Mediterranean diets (IMI and GMI). Additionally, according to our sex-stratified analyses, men who have greater adherence to dietary patterns have a decreased risk of major CVD for all patterns. The results suggest that greater adherence to dietary patterns positively influences blood biochemical and metabolic parameters, thus reducing the risk of developing cardiovascular disease and delaying the use of drug treatments.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41382518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Regular and Long-Term Effects of a Commercial Diet on Bone Mineral Density 商业饮食对骨密度的常规和长期影响
Pub Date : 2022-07-18 DOI: 10.3390/dietetics1020009
Ü. Parm, A. Tamm, Triin Aasmäe, Kaido Liiv, Aivar Orav, Ester Jaansoo, Kaisa Lohu, Irina Tamme
(1) Background: Although the effects of diets used worldwide, such as the Mediterranean diet, have been repeatedly studied, the effects of diet plans developed by national nutritionists are unknown. Our cross-sectional study aimed to assess the effects of the commercial Fitlap diet plan, widely used among Estonians, on bone mineral density (BMD), while considering other influential factors (physical activity, body composition, and macro- and micro-nutrients). (2) Methods: A total of 68 women participated (followers of Fitlap diet—FDF, n = 34; age-matched controls, n = 34). Body composition, bone mineral density (BMD), including the whole body (WB) and areal BMD from the femoral neck (FN) and lumbar spine (LS), and blood micro-nutrient levels were measured. The menu analysis was based on dietary recalls. (3) Results: The Fitlap diet contains significantly more calcium (p < 0.001) and magnesium (p = 0.007). FDF consume more fiber (coef. 6.49; p < 0.001) and protein (coef. 20.12; p < 0.001), which influences fat-free mass (coef. 3674.8; p = 0.008) and vitamin B12 blood values (coef. 184.98; p < 0.001). The only influencing factor of WB BMD, LS, and FN aBMD was fat-free mass (coef. in all locations 0.000009; and p = 0.015; p = 0.015; p = 0.01, respectively). (4) Conclusions: Fitlap is an example of a commercial diet plan that has no negative effects on bones.
(1) 背景:尽管世界各地使用的饮食(如地中海饮食)的影响已被反复研究,但国家营养学家制定的饮食计划的影响尚不清楚。我们的横断面研究旨在评估在爱沙尼亚人中广泛使用的商业Fitlap饮食计划对骨密度(BMD)的影响,同时考虑其他影响因素(体育活动、身体成分以及宏观和微观营养素)。(2) 方法:共有68名女性参与(Fitlap饮食-FDF的追随者,n=34;年龄匹配的对照组,n=34)。测量了身体成分、骨密度(BMD),包括全身(WB)和股骨颈(FN)和腰椎(LS)的面积BMD,以及血液微量营养水平。菜单分析基于饮食回忆。(3) 结果:Fitlap饮食含有显著更多的钙(p<0.001)和镁(p=0.007)。FDF消耗更多的纤维(系数6.49;p<0.001,FN aBDD是无脂肪质量(所有位置的系数分别为0.000009;和p=0.015;p=0.015;p=0.01)。(4) 结论:Fitlap是一个对骨骼没有负面影响的商业饮食计划的例子。
{"title":"Regular and Long-Term Effects of a Commercial Diet on Bone Mineral Density","authors":"Ü. Parm, A. Tamm, Triin Aasmäe, Kaido Liiv, Aivar Orav, Ester Jaansoo, Kaisa Lohu, Irina Tamme","doi":"10.3390/dietetics1020009","DOIUrl":"https://doi.org/10.3390/dietetics1020009","url":null,"abstract":"(1) Background: Although the effects of diets used worldwide, such as the Mediterranean diet, have been repeatedly studied, the effects of diet plans developed by national nutritionists are unknown. Our cross-sectional study aimed to assess the effects of the commercial Fitlap diet plan, widely used among Estonians, on bone mineral density (BMD), while considering other influential factors (physical activity, body composition, and macro- and micro-nutrients). (2) Methods: A total of 68 women participated (followers of Fitlap diet—FDF, n = 34; age-matched controls, n = 34). Body composition, bone mineral density (BMD), including the whole body (WB) and areal BMD from the femoral neck (FN) and lumbar spine (LS), and blood micro-nutrient levels were measured. The menu analysis was based on dietary recalls. (3) Results: The Fitlap diet contains significantly more calcium (p < 0.001) and magnesium (p = 0.007). FDF consume more fiber (coef. 6.49; p < 0.001) and protein (coef. 20.12; p < 0.001), which influences fat-free mass (coef. 3674.8; p = 0.008) and vitamin B12 blood values (coef. 184.98; p < 0.001). The only influencing factor of WB BMD, LS, and FN aBMD was fat-free mass (coef. in all locations 0.000009; and p = 0.015; p = 0.015; p = 0.01, respectively). (4) Conclusions: Fitlap is an example of a commercial diet plan that has no negative effects on bones.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49446058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Resveratrol on Metabolic, Biochemical, and Endocrine Manifestations in Polycystic Ovary Syndrome 白藜芦醇对多囊卵巢综合征代谢、生化和内分泌表现的影响
Pub Date : 2022-07-04 DOI: 10.3390/dietetics1020008
Pallavi Dubey, Ted Shi, Mallorie Coltharp, Sireesha Reddy
Polycystic Ovary Syndrome (PCOS) is a reproductive, hormonal, and metabolic disorder frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. Resveratrol is a naturally occurring polyphenolic stilbene found in trace amounts in some food items. It has been extensively used as a treatment option for metabolic disorders but its use in PCOS treatment has been limited. This review emphasizes the effect of resveratrol on the clinical features of PCOS, ovarian morphology, androgen profile, markers of oxidative stress, inflammatory markers, and metabolic markers associated with PCOS.
多囊卵巢综合征(PCOS)是一种生殖、激素和代谢紊乱,经常与胰岛素抵抗、高雄激素血症、慢性炎症和氧化应激有关。白藜芦醇是一种天然存在的多酚类二苯乙烯,在一些食品中存在微量。它已被广泛用作代谢紊乱的治疗选择,但在多囊卵巢综合征治疗中的应用有限。这篇综述强调了白藜芦醇对多囊卵巢综合征的临床特征、卵巢形态、雄激素水平、氧化应激标志物、炎症标志物和与多囊卵巢综合症相关的代谢标志物的影响。
{"title":"Effects of Resveratrol on Metabolic, Biochemical, and Endocrine Manifestations in Polycystic Ovary Syndrome","authors":"Pallavi Dubey, Ted Shi, Mallorie Coltharp, Sireesha Reddy","doi":"10.3390/dietetics1020008","DOIUrl":"https://doi.org/10.3390/dietetics1020008","url":null,"abstract":"Polycystic Ovary Syndrome (PCOS) is a reproductive, hormonal, and metabolic disorder frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. Resveratrol is a naturally occurring polyphenolic stilbene found in trace amounts in some food items. It has been extensively used as a treatment option for metabolic disorders but its use in PCOS treatment has been limited. This review emphasizes the effect of resveratrol on the clinical features of PCOS, ovarian morphology, androgen profile, markers of oxidative stress, inflammatory markers, and metabolic markers associated with PCOS.","PeriodicalId":72810,"journal":{"name":"Dietetics (Basel, Switzerland)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49632249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Dietetics (Basel, Switzerland)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1