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Comparing Self-Reported Dietary Intake to Provided Diet during a Randomized Controlled Feeding Intervention: A Pilot Study. 在随机控制喂养干预期间,比较自我报告的膳食摄入量和提供的膳食:试点研究。
Pub Date : 2023-12-01 Epub Date: 2023-11-17 DOI: 10.3390/dietetics2040024
James L Casey, Jennifer L Meijer, Heidi B IglayReger, Sarah C Ball, Theresa L Han-Markey, Thomas M Braun, Charles F Burant, Karen E Peterson

Systematic and random errors based on self-reported diet may bias estimates of dietary intake. The objective of this pilot study was to describe errors in self-reported dietary intake by comparing 24 h dietary recalls to provided menu items in a controlled feeding study. This feeding study was a parallel randomized block design consisting of a standard diet (STD; 15% protein, 50% carbohydrate, 35% fat) followed by either a high-fat (HF; 15% protein, 25% carbohydrate, 60% fat) or a high-carbohydrate (HC; 15% protein, 75% carbohydrate, 10% fat) diet. During the intervention, participants reported dietary intake in 24 h recalls. Participants included 12 males (seven HC, five HF) and 12 females (six HC, six HF). The Nutrition Data System for Research was utilized to quantify energy, macronutrients, and serving size of food groups. Statistical analyses assessed differences in 24 h dietary recalls vs. provided menu items, considering intervention type (STD vs. HF vs. HC) (Student's t-test). Caloric intake was consistent between self-reported intake and provided meals. Participants in the HF diet underreported energy-adjusted dietary fat and participants in the HC diet underreported energy-adjusted dietary carbohydrates. Energy-adjusted protein intake was overreported in each dietary intervention, specifically overreporting beef and poultry. Classifying misreported dietary components can lead to strategies to mitigate self-report errors for accurate dietary assessment.

基于自我报告饮食的系统误差和随机误差可能会对膳食摄入量的估计产生偏差。本试验研究的目的是通过比较 24 小时膳食回忆和对照喂养研究中提供的菜单项目来描述自我报告膳食摄入量的误差。该喂养研究采用平行随机区组设计,包括标准饮食(STD;15% 蛋白质、50% 碳水化合物、35% 脂肪)和高脂肪饮食(HF;15% 蛋白质、25% 碳水化合物、60% 脂肪)或高碳水化合物饮食(HC;15% 蛋白质、75% 碳水化合物、10% 脂肪)。在干预期间,参与者通过 24 小时回忆报告饮食摄入量。参与者包括 12 名男性(7 名 HC,5 名 HF)和 12 名女性(6 名 HC,6 名 HF)。研究营养数据系统用于量化能量、宏量营养素和各组食物的食用量。考虑到干预类型(STD vs. HF vs. HC),统计分析评估了 24 小时饮食回忆与提供的菜单项目之间的差异(学生 t 检验)。自我报告的摄入量与提供的膳食摄入量一致。高脂饮食的参与者少报了能量调整后的膳食脂肪,而高脂饮食的参与者少报了能量调整后的膳食碳水化合物。每种膳食干预都多报了能量调整后的蛋白质摄入量,特别是多报了牛肉和家禽。对误报的膳食成分进行分类,可为准确的膳食评估提供减少自我报告误差的策略。
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引用次数: 0
Historical Perspective and Current State Review: Advancing Lifelong Learning and Continuing Professional Education in Nutrition and Dietetics to Expand Opportunities, Equity, Access, and Future Transformations 历史视角与现状回顾:推进营养与营养学的终身学习和继续专业教育,以扩大机会、公平、获取和未来转型
Pub Date : 2023-11-08 DOI: 10.3390/dietetics2040023
Andie Lee Gonzalez, Patricia A. Lynch, Becky Dorner, Mary Beth Arensberg
Lifelong learning has been integral to advancement of the nutrition and dietetics profession and its practitioners. Both the United States (US) Commission on Dietetic Registration (CDR) and the Academy of Nutrition and Dietetics (Academy) advocate for continuous skill development and professional growth. Responding to evolving environmental trends and diverse practice perspectives, the CDR joined the Joint Accreditation for Interprofessional Continuing Education organization in 2020, and the CDR is transforming its own continuing professional education (CPE) requirements and prior-approval program. This paper presents a historical perspective and a current state narrative review, chronicling past and recent developments in nutrition and dietetics CPE in the US, including opportunities for reflective learning and interprofessional continuing education (IPCE). Also explored are the establishment and expansion of the Joint Accreditation organization and its standards, as well as applicable case examples. Additionally, this paper outlines the CDR and the Academy’s strategies for advancing inclusion, diversity, equity, and access (IDEA) within the profession and identifies how CPE advancements may facilitate accessible and equitable CPE for an increasingly diverse membership of practitioners. Nutrition and dietetics professionals stand to benefit from a more comprehensive understanding of changes in CPE and the opportunities they may bring to the future of the profession.
终身学习已经成为营养和饮食专业及其从业人员进步的组成部分。美国饮食注册委员会(CDR)和营养与饮食学会(Academy)都提倡持续的技能发展和专业成长。为了应对不断变化的环境趋势和多样化的实践观点,CDR于2020年加入了跨专业继续教育联合认证组织,CDR正在改变自己的继续职业教育(CPE)要求和预先批准程序。本文从历史的角度和现状的叙述回顾,记录了美国营养和营养学CPE的过去和最近的发展,包括反思性学习和跨专业继续教育(IPCE)的机会。探讨了联合认证机构的建立和扩展及其标准,以及适用的案例。此外,本文概述了CDR和学院在行业内促进包容性、多样性、公平性和可及性(IDEA)的战略,并确定了CPE的进步如何为日益多样化的从业者成员提供可及性和公平的CPE。营养和营养学专业人士将从更全面地了解CPE的变化以及它们可能为该专业的未来带来的机会中受益。
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引用次数: 0
A Narrative Review of the Tale of the Dysbiotic Microbiome in the Preterm Neonate 早产儿中益生菌群的叙述性回顾
Pub Date : 2023-10-24 DOI: 10.3390/dietetics2040022
Marwyn Sowden, Evette van Niekerk, Andre Nyandwe Hamama Bulabula, Mirjam Maria van Weissenbruch
Background: Researchers have established that the preterm neonate is born with an immature gastrointestinal tract. The preterm neonate is thus susceptible to various complications often seen in the neonatal intensive care unit, e.g., feeding intolerances, necrotizing enterocolitis, and hospital-acquired bloodstream infections. These complications can be life-threatening, and if survived, can have an unfavorable effect on the neonate’s growth and development. Aim: The aims of this narrative review article were to provide an in-depth understanding of the various factors contributing to the development of the preterm neonatal microbiome. Further, we reviewed gastrointestinal microbiome dysbiosis and its potential role in the development of feeding intolerances, necrotizing enterocolitis, and hospital-acquired bloodstream infections. Lastly, we described the potential role of probiotics in this vulnerable population. Methods: A PubMed database search was conducted identifying articles that describe the development and function of the neonatal microbiome, the role of gastrointestinal dysbiosis, and the development of neonatal complications as well as the role of probiotics in gastrointestinal dysbiosis. Results: Various maternal, neonatal, and environmental factors play a role in the development of gastrointestinal dysbiosis in the preterm neonate. This can lead to feeding intolerances, necrotizing enterocolitis, and hospital-acquired bloodstream infections. Discussion: The pathogenesis of the development of short-term complications in the preterm neonate can be linked to the immaturity of the host immune system as well as alterations seen in the intestinal microbiome. There is a growing body of evidence that probiotics can play a role in preventing dysbiosis and thus complications observed in the preterm neonate. However, the optimal combination of probiotic strains and dosage still needs to be identified.
背景:研究人员已经确定,早产新生儿出生时胃肠道不成熟。因此,早产新生儿易患新生儿重症监护病房常见的各种并发症,如喂养不耐受、坏死性小肠结肠炎和医院获得性血液感染。这些并发症可能危及生命,如果存活下来,可能对新生儿的生长发育产生不利影响。目的:这篇叙述性综述文章的目的是提供对早产儿微生物群发育的各种因素的深入了解。此外,我们回顾了胃肠道微生物群失调及其在喂养不耐受、坏死性小肠结肠炎和医院获得性血液感染发展中的潜在作用。最后,我们描述了益生菌在这一脆弱人群中的潜在作用。方法:检索PubMed数据库,识别描述新生儿微生物群的发育和功能、胃肠道生态失调的作用、新生儿并发症的发展以及益生菌在胃肠道生态失调中的作用的文章。结果:各种母体、新生儿和环境因素在早产儿胃肠生态失调的发展中起作用。这可导致进食不耐受、坏死性小肠结肠炎和医院获得性血流感染。讨论:早产新生儿短期并发症的发病机制可能与宿主免疫系统的不成熟以及肠道微生物群的改变有关。越来越多的证据表明,益生菌可以在预防生态失调和早产新生儿并发症方面发挥作用。然而,益生菌菌株和剂量的最佳组合仍有待确定。
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引用次数: 0
Exercise-Induced Gastrointestinal Symptoms in Endurance Sports: A Review of Pathophysiology, Symptoms, and Nutritional Management 耐力运动中运动引起的胃肠道症状:病理生理学、症状和营养管理的综述
Pub Date : 2023-09-19 DOI: 10.3390/dietetics2030021
Emanuela Ribichini, Giulia Scalese, Alessandra Cesarini, Chiara Mocci, Nadia Pallotta, Carola Severi, Enrico Stefano Corazziari
Strenuous exercise can be associated with “Exercise Induced Gastrointestinal Syndrome” (Ex-GIS), a clinical condition characterized by a series of gastrointestinal (GI) disturbances that may impact the physical and psychological performance of athletes. The pathophysiology comprises multi-factorial interactions between the GI tract and the circulatory, immune, enteric, and central nervous systems. There is considerable evidence for increases in the indices of intestinal damage, permeability, and endotoxemia associated with impaired gastric emptying, slowing of small intestinal transit, and malabsorption of nutrients. Heat stress and racing mode seem to exacerbate these GI disturbances. GI symptomatology that derives from strenuous exercise is similar to that of IBS and other GI functional disorders defined in the Rome IV Criteria. To manage Ex-GIS, the exercise modality, state of dehydration, environmental temperature, concomitant therapies, and self-managed diet should be evaluated, and if risk elements are present, an attempt should be made to modify them. Multiple strategies can be successively adopted to manage Ex-GIS. Nutritional and behavioral interventions appear to be the principal ones to avoid symptoms during the exercise. The aim of this review will be to explore the pathophysiology, clinical aspect, and current literature on behavioral and nutritional strategies to manage Ex-GIS, regarding a gluten-free diet and low-fermentable oligo-, di-, and mono-saccharides and polyols (FODMAP) diet.
剧烈运动可能与“运动诱发胃肠道综合征”(Ex-GIS)有关,这是一种以一系列胃肠道(GI)紊乱为特征的临床疾病,可能会影响运动员的生理和心理表现。病理生理包括胃肠道与循环系统、免疫系统、肠系统和中枢神经系统之间的多因素相互作用。大量证据表明,肠道损伤、渗透性和内毒素血症指数的增加与胃排空受损、小肠运输减慢和营养物质吸收不良有关。热应激和赛车模式似乎加剧了这些胃肠道紊乱。剧烈运动引起的胃肠道症状与IBS和Rome IV标准中定义的其他胃肠道功能障碍相似。要管理Ex-GIS,应评估运动方式、脱水状态、环境温度、伴随疗法和自我管理饮食,如果存在风险因素,应尝试修改它们。对Ex-GIS的管理可以先后采用多种策略。营养和行为干预似乎是避免运动中出现症状的主要方法。本综述的目的是探讨无麸质饮食和低发酵寡糖、二糖、单糖和多元醇(FODMAP)饮食中管理Ex-GIS的行为和营养策略的病理生理学、临床方面和当前文献。
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引用次数: 0
The Lower the Better? Discussion on Non-Alcoholic Wine and Its Marketing 越低越好?论无酒精葡萄酒及其营销
Pub Date : 2023-08-30 DOI: 10.3390/dietetics2030020
Frederik Nikolai Schulz, H. Farid, J. Hanf
In the German beverage market, a shift in consumption has become apparent in recent decades: away from alcoholic beverages and towards non-alcoholic alternatives. This indicates a tradeoff between two important and nutritionally relevant substances: alcohol and sugar. This review, therefore, addresses the question of the significance of these developments to the German wine industry, where non-alcoholic wines and sparkling wines are becoming increasingly important. The production of these products is accompanied by a reduction in alcohol content with a simultaneous increase in sugar. Furthermore, these products could also become the focus of health policy efforts when it comes to accusations of possible “alibi marketing”. Here, parallels with the handling of tobacco products become clear, while the tradeoff between alcohol and sugar recedes into the background.
在德国饮料市场,近几十年来消费的转变已经变得很明显:从酒精饮料转向非酒精饮料。这表明两种重要且与营养有关的物质:酒精和糖之间的权衡。因此,本审查将探讨这些发展对德国葡萄酒工业的意义,在德国,不含酒精的葡萄酒和起泡葡萄酒正变得越来越重要。这些产品的生产伴随着酒精含量的降低,同时糖的含量增加。此外,当涉及到可能的“不在场营销”指控时,这些产品也可能成为卫生政策努力的焦点。在这里,处理烟草产品的相似之处变得清晰起来,而酒精和糖之间的权衡则退居幕后。
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引用次数: 0
Lessons Learnt from Rapid Implementation of Telehealth in a Paediatric Dietetics’ Outpatient Service: Is There a Silver Lining beyond the Coronavirus Pandemic to Support Patient-Centred Care? 在儿科营养师门诊服务中快速实施远程医疗的经验教训:在冠状病毒大流行之外,支持以患者为中心的护理是否还有一线希望?
Pub Date : 2023-08-04 DOI: 10.3390/dietetics2030019
Araceli Llanos Jeri, K. Lambert, M. Mak, M. Diamantes
The aim of this paper is to report on the differences in clinical and service engagement outcomes of patients attending the paediatric dietetic outpatient service at a major metropolitan hospital before the outbreak of the coronavirus (using face-to-face care) and during the pandemic (using telehealth). This paper also reports on learning lessons from the rapid implementation of telehealth in this service. This study collected pre- and post-coronavirus pandemic data from 44 paediatric patients. Data on outcomes pre- and post-implementation were analysed. There were no statistically significant differences between pre- and post-coronavirus data for growth (p = 0.92), adherence to dietetic recommendations (p = 0.08) or attendance rate (p = 1.00). This study also found a low uptake of virtual telehealth, technical issues and suboptimal anthropometric data collection associated with this modality of care. Telehealth was not associated with a change in clinical and service engagement outcomes. Thus, telehealth service delivery is not inferior to usual face–face dietetic care and has the potential to be a useful adjunct to usual nutrition care for paediatric health service users after the coronavirus pandemic.
本文的目的是报告在冠状病毒爆发前(使用面对面护理)和大流行期间(使用远程医疗)在大型大都市医院参加儿科饮食门诊服务的患者的临床和服务参与结果的差异。本文还报告了在该服务中快速实施远程医疗的经验教训。本研究收集了44名儿科患者冠状病毒大流行前后的数据。对实施前后的结果数据进行了分析。在生长(p = 0.92)、遵守饮食建议(p = 0.08)或出勤率(p = 1.00)方面,冠状病毒感染前和感染后的数据没有统计学上的显著差异。该研究还发现,虚拟远程医疗的使用率较低,技术问题和与这种护理方式相关的人体测量数据收集不理想。远程保健与临床和服务参与结果的变化无关。因此,远程保健服务的提供并不逊于通常的面对面饮食保健,并且有可能成为冠状病毒大流行后儿科卫生服务用户常规营养保健的有用补充。
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引用次数: 0
The Relationship of Fruits and Fruit-Products Consumption with Glucose Homeostasis and Diabetes: A Comprehensive Update on the Current Clinical Literature 水果和水果制品消费与葡萄糖稳态和糖尿病的关系:对当前临床文献的全面更新
Pub Date : 2023-07-20 DOI: 10.3390/dietetics2030018
I. Ellouze, Neda S. Akhavan, Saiful Singar, Kallie Dawkins, R. Nagpal, B. Arjmandi
Type 2 diabetes mellitus is a major contributor to morbidity and mortality worldwide. This disease often leads to poor health outcomes, such as neuropathy and diabetic foot ulcers, and increased risk for comorbidities such as cardiovascular complications and renal disease. Lifestyle modifications including diet and physical activity interventions are often explored as prevention and management strategies for T2DM. It is well established that fruits are a rich source of fiber and a variety of phytochemicals, vitamins, minerals, and bioactive compounds that can help optimize human health. Unfortunately, many experts associate the consumption of fruit with a moderate to high glycemic index (GI), which leads to a spike in blood glucose and eventually elevated hemoglobin A1c (HbA1c). The purpose of this comprehensive review is to outline the current clinical literature on the relationship between fruit consumption and various indices of glucose metabolism. A variety of fruits have been clinically studied to determine this relationship, namely in the fresh form (e.g., berries, apples, watermelon, cherries, mangoes), dried fruits (raisins and dates), and juices (derived from cranberry, orange, grape, cherry, and pomegranate). Overall, intake of fruits and fruit-derived products is beneficial for healthy subjects and subjects with T2DM regarding their impact on glucose metabolism and other cardiometabolic markers (e.g., inflammatory responses, lipid profiles). Nonetheless, it is more advisable for diabetic patients to consume fresh or dried fruits rather than fruit-derived products. A special consideration needs to be attributed to both the amount of fruit intake with regards to their respective GI and glycemic load (GL), and when these fruits are consumed. Trials with more a comprehensive design and specific outcomes are required to reveal the mechanisms underlying the beneficial effects of fruit consumption on the T2DM population particularly.
2型糖尿病是世界范围内发病率和死亡率的主要原因。这种疾病通常会导致不良的健康结果,如神经病变和糖尿病足溃疡,并增加心血管并发症和肾脏疾病等合并症的风险。生活方式的改变,包括饮食和身体活动干预,经常被探索作为预防和管理2型糖尿病的策略。众所周知,水果是纤维和各种植物化学物质、维生素、矿物质和生物活性化合物的丰富来源,有助于优化人类健康。不幸的是,许多专家将食用水果与中高血糖指数(GI)联系在一起,这会导致血糖飙升,最终导致血红蛋白糖化血红蛋白(HbA1c)升高。这篇综述的目的是概述目前关于水果摄入与葡萄糖代谢各项指标之间关系的临床文献。临床研究了各种水果以确定这种关系,即新鲜形式(如浆果、苹果、西瓜、樱桃、芒果)、干果(葡萄干和枣)和果汁(来自蔓越莓、橙子、葡萄、樱桃和石榴)。总的来说,摄入水果和水果衍生产品对健康受试者和2型糖尿病受试者有益,因为它们对葡萄糖代谢和其他心脏代谢标志物(如炎症反应、脂质谱)有影响。尽管如此,对于糖尿病患者来说,食用新鲜或干果比食用水果衍生产品更可取。需要特别考虑的是水果的摄入量与它们各自的GI和血糖负荷(GL)有关,以及这些水果的食用时间。需要更全面的设计和具体结果的试验来揭示水果消费对2型糖尿病人群有益作用的机制。
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引用次数: 0
Effect of Cocoa Beverage and Dark Chocolate Intake on Lipid Profile in People Living with Normal and Elevated LDL Cholesterol: A Systematic Review and Meta-Analysis 可可饮料和黑巧克力摄入对低密度脂蛋白胆固醇正常和升高人群脂质状况的影响:系统综述和荟萃分析
Pub Date : 2023-07-07 DOI: 10.3390/dietetics2030017
I. Amoah, Jia Jiet Lim, Emmanuel Ofori Osei, M. Arthur, Jesse Charles Cobbinah, Phyllis Tawiah
Cocoa beverage and dark chocolate are important dietary sources of polyphenol and have been hypothesised to improve the lipid profile. This systematic review and meta-analysis aimed to investigate the effect of cocoa beverage and dark chocolate intake on lipid profile in individuals living with normal and elevated LDL cholesterol. The question on whether cocoa beverage and chocolate differentially modify the lipid profile was also explored. A systematic literature search was conducted on PubMed and Cochrane Library on 26 February 2022 following the PRISMA guideline. Cocoa beverage and chocolate consumption had no significant effect on circulating concentrations of total cholesterol, LDL cholesterol, and triglycerides (p > 0.05, all), but favourably and significantly increased circulating concentration of HDL cholesterol by 0.05 (95% CI [0.02, 0.09]) mmol/L (p = 0.002). Changes in lipid profile were similar when comparing populations with normal vs. elevated LDL cholesterol (p > 0.05, all). When considering the food matrix, cocoa beverage intake significantly increased HDL cholesterol by 0.11 (95% CI [0.06, 0.17]) mmol/L (p < 0.001), but the improvement in HDL cholesterol was not significant when chocolate (p = 0.10) or a combination of cocoa beverage and chocolate (p = 0.19) (subgroup differences, p = 0.03) was administered. Cocoa consumption could be recommended as part of a healthy diet in the general population with normal and elevated LDL cholesterol.
可可饮料和黑巧克力是多酚的重要膳食来源,据推测可以改善血脂。本系统综述和荟萃分析旨在探讨可可饮料和黑巧克力摄入量对低密度脂蛋白胆固醇正常和升高个体的脂质特征的影响。探讨了可可饮料和巧克力是否对脂质谱有不同的改变。根据PRISMA指南,于2022年2月26日对PubMed和Cochrane Library进行了系统的文献检索。可可饮料和巧克力摄入对总胆固醇、低密度脂蛋白胆固醇和甘油三酯循环浓度无显著影响(p < 0.05),但显著提高了高密度脂蛋白胆固醇循环浓度0.05 (95% CI [0.02, 0.09]) mmol/L (p = 0.002)。当比较LDL胆固醇正常与升高的人群时,脂质谱的变化相似(p < 0.05,均)。当考虑食物基质时,摄入可可饮料可显著提高高密度脂蛋白胆固醇0.11 (95% CI [0.06, 0.17]) mmol/L (p < 0.001),但当摄入巧克力(p = 0.10)或可可饮料和巧克力的组合(p = 0.19)(亚组差异,p = 0.03)时,HDL胆固醇的改善不显著。对于低密度脂蛋白胆固醇水平正常或升高的普通人群,可以推荐食用可可作为健康饮食的一部分。
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引用次数: 1
Nutritional Adequacy and Patient Perceptions of the Hospital Inpatient Haemodialysis Menu: A Mixed Methods Case Series 医院住院患者血液透析菜单的营养充足性和患者认知:混合方法病例系列
Pub Date : 2023-06-21 DOI: 10.3390/dietetics2030016
Kate Neal, Fatima Al Nakeeb, K. Lambert
Aim: To evaluate the nutritional adequacy of the hospital haemodialysis menu, quantify the dietary intake of hospitalised haemodialysis patients and explore patient perceptions of the menu. Methods: The menu analysis compared the default menu to reference standards using a one sample t-test via SPSS. Eight hospitalised haemodialysis patients were purposively interviewed using semi-structured interviews. Thematic analysis was used to identify the dominant themes. The participant’s actual dietary intake was calculated and compared to individual nutrients using evidence-based guidelines. Results: Compared to the reference standards, the default inpatient haemodialysis menu did not provide adequate energy (p < 0.001, mean = 8767 kJ/day ± 362), sodium (p < 0.001, mean = 72 mmol/day ± 9), potassium (p < 0.001, mean = 64 mmol/day ± 4), vitamin C (p ≤ 0.001, mean = 33 mg/day ± 10) and fibre (p < 0.001, mean = 26 g/day ± 3). Inadequate intake of energy and protein occurred in half of the participants. Passive acceptance of the menu, environmental and cultural considerations contributed to missed food opportunities impacting the patient experience and limited intake. Conclusions: The profile of the current default inpatient haemodialysis menu impacts the dietary intake and the experience of haemodialysis inpatients. It is recommended that the default menu is optimised in line with evidence-based guidelines for inpatients.
目的:评估医院血液透析菜单的营养充足性,量化住院血液透析患者的饮食摄入量,并探讨患者对菜单的看法。方法:菜单分析通过SPSS进行单样本t检验,将默认菜单与参考标准进行比较。八名住院的血液透析患者采用半结构化访谈进行了有针对性的访谈。专题分析用于确定主要专题。使用循证指南计算参与者的实际饮食摄入量,并将其与个体营养素进行比较。结果:与参考标准相比,默认的住院血液透析菜单没有提供足够的能量(p<0.001,平均值=8767千焦/天±362)、钠(p<001,平均值=72毫摩尔/天±9)、钾(p<0.01,平均值=64毫摩尔/日±4)、维生素C(p≤0.001,平均数=33毫克/天±10)和纤维(p<.001,平均值=26克/天±3)。一半的参与者能量和蛋白质摄入不足。对菜单的被动接受、环境和文化因素导致错过了影响患者体验和摄入有限的食物机会。结论:目前默认的住院患者血液透析菜单影响血液透析住院患者的饮食摄入和体验。建议根据住院患者循证指南对默认菜单进行优化。
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引用次数: 0
Perilla Oil, An Omega-3 Unsaturated Fatty Acid-Rich Oil, Enhances Diversity of Gut Microbiota and May Relieve Constipation in Sedentary Healthy Female: A Nonrandomized Placebo-Controlled Pilot Study 紫苏油是一种富含Omega-3不饱和脂肪酸的油,可增强肠道微生物群的多样性,并可缓解久坐健康女性的便秘:一项非随机安慰剂对照的初步研究
Pub Date : 2023-06-19 DOI: 10.3390/dietetics2020015
A. Kawamura, M. Sugita
This study shows the effect of omega-3 unsaturated fatty acids via perilla oil intake on gut microbiota and constipation. Eight sedentary females participated in a nonrandomized placebo-controlled pilot study consisting of eight-week perilla oil (OIL) and placebo (PLA) intervention phases. There was a 10-month washout period between phases. All participants received 9 g of perilla oil-containing jelly in the OIL phase, and a placebo jelly in the PLA phase. Gut microbiota, α-diversity, and constipation scores were measured pre- and post-intervention in both phases. The α-diversity, an important indicator of gut microbiota diversity, was significantly increased post-intervention (4.5 ± 0.1) compared to pre-intervention (3.8 ± 0.3) in the OIL only (p = 0.021). Notably, the level of α-diversity was maintained even after the washout period of 10 months. Butyrate-producing bacteria, Lachnospiraceae (%), did not change in the OIL but were significantly reduced post-intervention (15.1 ± 4.8) compared to pre-intervention (20.1 ± 7.0) in the PLA (p = 0.040). In addition, the constipation scores were significantly or tended to be reduced during the OIL phase only (p < 0.05, p < 0.1). In conclusion, an eight-week perilla oil supplementation may enhance and establish the diversity of gut microbiota, which may relieve constipation.
这项研究表明,通过紫苏油摄入omega-3不饱和脂肪酸对肠道微生物群和便秘的影响。八名久坐不动的女性参加了一项非随机安慰剂对照先导研究,包括为期八周的紫苏油(oil)和安慰剂(PLA)干预阶段。两个阶段之间有10个月的洗脱期。所有参与者在OIL期服用9g紫苏油果冻,在PLA期服用安慰剂果冻。在干预前和干预后分别测量肠道菌群、α-多样性和便秘评分。α-多样性是衡量肠道菌群多样性的重要指标,干预后OIL组α-多样性(4.5±0.1)显著高于干预前(3.8±0.3)(p = 0.021)。值得注意的是,即使在10个月的洗脱期后,α-多样性水平仍保持不变。产丁酸菌Lachnospiraceae(%)在OIL中没有变化,但与干预前(20.1±7.0)相比,干预后显著减少(15.1±4.8)(p = 0.040)。此外,便秘评分仅在OIL期显著或倾向于降低(p < 0.05, p < 0.1)。综上所述,为期8周的紫苏油补充可以增强和建立肠道微生物群的多样性,从而缓解便秘。
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引用次数: 0
期刊
Dietetics (Basel, Switzerland)
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