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Cardioprotective Effects of Resveratrol in the Mediterranean Diet: A Short Narrative Review 地中海饮食中白藜芦醇的心脏保护作用:一个简短的回顾
Pub Date : 2023-05-26 DOI: 10.3390/dietetics2020014
C. Capurso, F. Bellanti, A. Lo Buglio, G. Vendemiale
The beneficial effects of a Mediterranean diet are due to the numerous active compounds in the food and, particularly, the high concentration of compounds with synergistically acting antioxidant properties. Resveratrol, a stilbenoid nonflavonoid phenol, is an antioxidant that is naturally produced by numerous plants as a defensive agent in response to attacks from pathogens, such as bacteria and fungi. Resveratrol has several effects on human health, including on the lipid profile, where it primarily downregulates the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase, reducing the synthesis of cholesterol. Resveratrol also increases the expression of LDL receptors in the liver, contributing to the reduction in the LDL-cholesterol levels. This short narrative review, based on relevant articles written in English from a PubMed search, using the keywords “resveratrol”, “atherosclerosis”, “cardiovascular disease”, and “Mediterranean Diet“, focuses on the possible effects of this molecule on cardiovascular disease, lipid metabolism, and atherosclerosis.
地中海饮食的有益效果是由于食物中含有大量的活性化合物,特别是具有协同抗氧化特性的高浓度化合物。白藜芦醇是一种苯乙烯类非类黄酮酚,是一种抗氧化剂,由许多植物自然产生,作为抵抗病原体(如细菌和真菌)攻击的防御剂。白藜芦醇对人体健康有若干影响,包括对血脂的影响,其中它主要下调3-羟基-3-甲基戊二酰辅酶A还原酶,减少胆固醇的合成。白藜芦醇还能增加肝脏中低密度脂蛋白受体的表达,有助于降低低密度脂蛋白胆固醇水平。本文以PubMed检索的相关英文文章为基础,使用关键词“白藜芦醇”、“动脉粥样硬化”、“心血管疾病”和“地中海饮食”,重点研究白藜芦醇分子对心血管疾病、脂质代谢和动脉粥样硬化的可能影响。
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引用次数: 1
A Prospective Study Measuring the Effect of an Interactive Educational Program on Overweight and Obesity among School-Aged Children 一项测量互动教育计划对学龄儿童超重和肥胖影响的前瞻性研究
Pub Date : 2023-05-06 DOI: 10.3390/dietetics2020013
Israel Ríos-Castillo, Lisbeth Escala, Ledys Urriola, M. McKinnon, Stephen R. Kodish, Carlos Rojas-Roque
Being overweight or obese is a public health problem. This work evaluated a food and nutrition education (FNE) intervention to reduce overweight status among schoolchildren in four schools in the West Panama Province. This was a quasi-experimental before-and-after study that implemented a 34-week FNE intervention through workshops with didactic material to 403 children between 8 and 13 years old. A knowledge and attitude survey was used as an evaluation tool before and after the FNE intervention. The prevalence of excess weight (40%) did not reduce after the intervention. The zBMI at the beginning was 0.57 (1.29) for girls and 0.70 (1.36) for boys, and at the final evaluation was 0.57 (1.28) for girls and 0.67 (1.33) for boys. No significant differences were observed between the point of evaluation and sex. No differences were reported in the median level of attitude, although higher levels of knowledge were reported in students of both sexes. The FNE in schoolchildren can be effective in acquiring knowledge and maintaining a positive attitude towards food, but more research is needed to address nutritional status. Although the intervention had no impact on nutritional status, the FNE facilitated the adoption of skills and competencies in schoolchildren. The success of the implementation of the study highlighted the feasibility of replicating the FNE interventions on a larger scale to contribute positively to the multi-level and sectoral public policy Study Without Hunger in Panama.
超重或肥胖是一个公共健康问题。本研究评估了在西巴拿马省四所学校开展的食品和营养教育(FNE)干预,以减少在校学生的超重状况。这是一项准实验前后对比研究,对403名8至13岁的儿童进行了为期34周的FNE干预,通过讲习班提供教学材料。在FNE干预前后使用知识和态度调查作为评估工具。超重的患病率(40%)在干预后没有减少。开始时,女孩的zBMI为0.57(1.29),男孩为0.70(1.36),最终评估时,女孩为0.57(1.28),男孩为0.67(1.33)。在评价点和性别之间没有观察到显著差异。虽然两性学生的知识水平较高,但在态度的中位数水平上没有差异。小学生的FNE可以有效地获取知识和保持对食物的积极态度,但需要更多的研究来解决营养状况。虽然干预措施对营养状况没有影响,但FNE促进了学龄儿童采用技能和能力。这项研究的成功实施突出表明,在更大范围内复制国家计划署的干预措施,对巴拿马多层次和部门性的“无饥饿研究”公共政策作出积极贡献是可行的。
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引用次数: 0
A Narrative Review on Eating Disorders and Disordered Eating in Inflammatory Bowel Diseases: Need for Increased Awareness 关于炎症性肠病中饮食失调和饮食失调的综述:需要提高认识
Pub Date : 2023-04-24 DOI: 10.3390/dietetics2020012
F. D. Di Giorgio, P. Melatti, S. Ciminnisi, M. Cappello
Recent evidence suggests a link between Inflammatory Bowel Disease (IBD) and eating disorders, an emerging complex bidirectional association. Indeed, the overlap of symptoms and signs can lead to delayed diagnosis and misdiagnosis of both conditions, but also the fear of food-induced symptoms, commonly observed in patients with IBD, determines dietary restrictions which in predisposed individuals may induce an overt eating disorder. ARFID (Avoidant Restrictive Food Intake Disorder) and anorexia nervosa are the eating disorders more frequently reported, while disordered eating and orthorexia nervosa are emerging conditions. Disease worsening due to refusal of therapies in patients with anorexia is also a matter of concern and an increased awareness of the possible association of these conditions by gastroenterologists and dietitians is strongly warranted in order for patients to receive the appropriate counseling.
最近的证据表明炎症性肠病(IBD)和饮食失调之间存在联系,这是一种新兴的复杂双向关联。的确,症状和体征的重叠可能导致这两种疾病的延误诊断和误诊,而且对食物引起的症状的恐惧,通常在IBD患者中观察到,决定了饮食限制,这在易感个体中可能导致明显的饮食失调。回避性限制性食物摄入障碍(ARFID)和神经性厌食症是较常报道的饮食失调,而饮食失调和神经性厌食症是新出现的疾病。厌食症患者因拒绝治疗而导致的疾病恶化也是一个值得关注的问题,胃肠病学家和营养师强烈要求提高对这些疾病可能关联的认识,以便患者接受适当的咨询。
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引用次数: 0
Association between Time from Dinner to Bedtime and Sleep Quality Indices in the Young Japanese Population: A Cross-Sectional Study 日本年轻人从晚饭到睡觉时间与睡眠质量指数的相关性:一项横断面研究
Pub Date : 2023-04-12 DOI: 10.3390/dietetics2020011
J. Yasuda, Nanami Kishi, S. Fujita
Sleep quality (duration, efficiency, and latency) is directly associated with human health. An interventional study reported that the time of dinner influenced sleep latency, suggesting that it may also be associated with other sleep quality indices under free-living conditions. Therefore, we cross-sectionally examined the association between the time from dinner to bedtime (TDB) and sleep quality indices under free-living conditions in the young Japanese population. Based on the TDB, 264 participants were separated into three quantiles (T1, ≤3.79 h; T2, 3.80–4.94 h; T3, ≥4.95 h from dinner to bedtime). The T1 (mean ± standard error; 26.4 ± 2.2 min, p = 0.081) and T2 groups (30.8 ± 2.2 min, p = 0.001) showed longer sleep latency compared to the T3 group (19.6 ± 2.2 min), after adjusting for confounding factors. Sleep efficiency in the T1 group (77.5 ± 1.6%) tended to be greater than in the T3 group (72.1 ± 1.6%, p = 0.061), whereas sleep efficiency in the T2 group was not significantly different (77.0 ± 1.6%) from that in the T1 group. Therefore, shortened TDB was associated with prolonged sleep latency in free-living conditions. Meal timing, especially dinner, should be considered along with other sleep hygiene measures to improve human health.
睡眠质量(持续时间、效率和潜伏期)与人体健康直接相关。一项介入性研究报告说,晚餐的时间影响睡眠潜伏期,这表明它也可能与自由生活条件下的其他睡眠质量指标有关。因此,我们横断面研究了日本年轻人在自由生活条件下从晚餐到就寝时间(TDB)与睡眠质量指数之间的关系。根据TDB将264名参与者分为三个分位数(T1,≤3.79 h;T2, 3.80-4.94 h;T3,从晚餐到就寝时间≥4.95 h)。T1(平均值±标准误差;校正混杂因素后,T2组(30.8±2.2 min, p = 0.001)和T2组(26.4±2.2 min, p = 0.081)的睡眠潜伏期明显长于T3组(19.6±2.2 min)。T1组睡眠效率(77.5±1.6%)高于T3组(72.1±1.6%,p = 0.061),而T2组睡眠效率与T1组无显著差异(77.0±1.6%)。因此,在自由生活条件下,TDB缩短与睡眠潜伏期延长有关。用餐时间,尤其是晚餐,应该与其他睡眠卫生措施一起考虑,以改善人类健康。
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引用次数: 1
Perceived Barriers and Facilitators to a Healthy Diet among Cancer Survivors: A Qualitative Exploration Using the TDF and COM-B 癌症幸存者健康饮食的感知障碍和促进因素:使用TDF和COM-B的定性探索
Pub Date : 2023-03-15 DOI: 10.3390/dietetics2010010
L. Keaver, P. Douglas, N. O’Callaghan
Cancer survivors consider nutrition to be highly important and are motivated to seek information about lifestyle changes, including nutrition, to improve their long-term health. Despite this, suboptimal dietary intake is still reported. Understanding cancer-specific barriers and facilitators to healthy eating among this population could help develop targeted interventions for this group. This study explored the barriers and facilitators to following a healthy diet among cancer survivors using the Theoretical Domains Framework (TDF) and COM-B model. Semi-structured focus groups with 20 cancer survivors were conducted between February and August 2021, which were transcribed verbatim. Seven key TDF domains accounted for 87% of all coded responses. These were (a) environmental context and resources; (b) knowledge; (c) behavioural regulation; (d) social/professional role and identity; (e) belief about consequences; (f) social influences; and (g) skills. Key barriers were lack of knowledge, non-specific or irrelevant information, environmental aspects, and family. Facilitators were awareness of the importance of nutrition, the health benefits of a plant-based diet, confidence in cooking skills, organisation, balance, family, time, and viewing themselves as someone who eats healthily and access to fresh produce. Enablement was the most prominently linked intervention function. This work can inform future interventions in this area and ensure they are end-user-centred.
癌症幸存者认为营养非常重要,并积极寻求有关生活方式改变的信息,包括营养,以改善他们的长期健康。尽管如此,仍有报道称饮食摄入不理想。了解这一人群中癌症特异性障碍和促进健康饮食的因素有助于为这一群体制定有针对性的干预措施。本研究利用理论域框架(TDF)和COM-B模型探讨了癌症幸存者遵循健康饮食的障碍和促进因素。2021年2月至8月,对20名癌症幸存者进行了半结构焦点小组,并逐字转录。7个关键TDF域占所有编码响应的87%。这些是(a)环境背景和资源;(b) 知识;(c) 行为调节;(d) 社会/职业角色和身份;(e) 对后果的信念;(f) 社会影响;以及(g)技能。主要障碍是缺乏知识、不具体或不相关的信息、环境因素和家庭。促进者意识到营养的重要性,植物性饮食对健康的益处,对烹饪技能、组织、平衡、家庭、时间的信心,并将自己视为一个吃得健康、能获得新鲜农产品的人。促成是最突出的干预职能。这项工作可以为该领域的未来干预措施提供信息,并确保这些干预措施以最终用户为中心。
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引用次数: 0
The Effect of Plant-Based and Mycoprotein-Based Meat Substitute Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis of Controlled Intervention Trials 以植物和真菌蛋白为基础的肉类替代品消费对心脏代谢危险因素的影响:对照干预试验的系统评价和荟萃分析
Pub Date : 2023-03-08 DOI: 10.3390/dietetics2010009
Joshua Gibbs, Gah-Kai Leung
Background: Climate change is a serious threat to human wellbeing and development. Global reduction of meat intake is key to addressing climate change and other modern sustainability challenges. Plant-based and mycoprotein-based meat substitutes are predicted to play a key role in the reduction of meat intake; however, their impact on human health is unclear. The main objective of this meta-analysis was to assess the short-term effects of meat substitutes on important cardiometabolic biomarkers (total cholesterol, TC; LDL-cholesterol, LDL-C; HDL-cholesterol, HDL-C; triglycerides, TG; systolic blood pressure, SBP; diastolic blood pressure, DBP; fasting blood glucose, FBG; weight) in controlled clinical trials. Methods: Embase and MEDLINE were searched to identify controlled clinical trials with meat substitute interventions and cardiometabolic biomarker outcomes. Standardised mean differences in TC, LDL-C, HDL-C, TG, FBG, SBP, DBP, and weight and 95% confidence intervals were pooled using a random effects model. Risk of bias, heterogeneity, sensitivity, and publication bias were assessed. Of the 934 records identified, 12 studies met the inclusion criteria. In the pooled analyses, the consumption of meat substitutes was associated with significantly lower TC (−0.50 mmol/L [95% CIs −0.70, −0.29]), LDL-C (−0.39 mmol/L [−0.57, −0.21]), and TG (−0.15 mmol/L [−0.29, −0.01]), non-significantly lower FBG (−0.08 [−0.23, 0.08]), SBP (−0.32 [−1.79, 1.41]), and weight (−0.12 [−1.52, 1.27]), and non-significantly higher HDL-C (0.01 [−0.02, 0.05]) and DBP (0.49 [−0.30, 1.28]). There was evidence of publication bias, and some heterogeneity was detected. The certainty of evidence was moderate for the TC and HDL-C results, low for the LDL-C, TG, SBP, DBP, and weight results, and very low for the FBG results. Conclusions: Replacement of some or all meat with plant-based or mycoprotein-based substitutes may lower TC, LDL-C, and TG.
背景:气候变化对人类福祉和发展构成严重威胁。全球减少肉类摄入是应对气候变化和其他现代可持续性挑战的关键。基于植物和真菌蛋白的肉类替代品预计将在减少肉类摄入方面发挥关键作用;然而,它们对人类健康的影响尚不清楚。这项荟萃分析的主要目的是评估肉类替代品对对照临床试验中重要心脏代谢生物标志物(总胆固醇,TC;低密度脂蛋白胆固醇,LDL-C;高密度脂蛋白-胆固醇,HDL-C;甘油三酯,TG;收缩压,SBP;舒张压,DBP;空腹血糖,FBG;体重)的短期影响。方法:检索Embase和MEDLINE,以确定肉类替代干预和心脏代谢生物标志物结果的对照临床试验。使用随机效应模型汇总TC、LDL-C、HDL-C、TG、FBG、SBP、DBP和体重的标准化平均差异和95%置信区间。评估了偏倚、异质性、敏感性和发表偏倚的风险。在确定的934份记录中,有12项研究符合纳入标准。在汇总分析中,肉类替代品的消费与TC(−0.50 mmol/L[95%CI−0.70,−0.29])、LDL-C(−0.39 mmol/L[-0.57,−0.21])和TG(−0.15 mmol/L[-0.29,−0.01])显著降低有关,FBG(−0.08[−0.23,0.08])、SBP(−0.32[−1.79,1.41])和体重(−0.12[−1.52,1.27])不显著降低有关,HDL-C(0.01[-0.02,0.05])和DBP(0.49[-0.30,1.28])无显著升高。有证据表明存在发表偏倚,并检测到一些异质性。TC和HDL-C结果的证据确定性中等,LDL-C、TG、SBP、DBP和体重结果的证据可靠性较低,FBG结果的证据可信度非常低。结论:用植物性或真菌蛋白替代品替代部分或全部肉类可以降低TC、LDL-C和TG。
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引用次数: 3
Trace Minerals and Anxiety: A Review of Zinc, Copper, Iron, and Selenium 微量元素与焦虑:锌、铜、铁和硒的研究综述
Pub Date : 2023-02-20 DOI: 10.3390/dietetics2010008
Melissa S. Totten, Tyler S. Davenport, Laken F. Edwards, Jenna M. Howell
Anxiety disorder is characterized by excessive fear or avoidance of perceived threats that can be persistent and debilitating. Diet is a modifiable risk factor that may contribute to the pathogenesis or treatment of anxiety, depending on diet quality. Although the biological mechanisms by which food, specific nutrients, and nutraceuticals impact mental health are not completely understood, implicated pathways include inflammation, oxidative stress, brain plasticity effects, mitochondrial dysfunction, and neurotransmitter metabolism. Essential dietary trace minerals such as zinc, copper, iron, and selenium are critical components for numerous biological proteins and may have a role in these proposed mechanisms related to brain health and anxiety. This narrative review examines the influence of essential trace elements zinc, copper, iron, and selenium on anxiety symptoms based on the latest peer-reviewed scientific evidence. Current research indicates that deficiencies in zinc, iron, and selenium are associated with anxiety, while copper overload may impact anxiety to a greater degree than copper deficiency. Further investigation is needed to understand the specific neurobiological mechanisms involved. Overall, the collective findings demonstrate the importance of optimizing trace mineral homeostasis for the mitigation of anxiety disorders and preservation of mental health.
焦虑障碍的特征是过度恐惧或回避感知到的威胁,这些威胁可能持续并使人虚弱。饮食是一种可改变的风险因素,可能对焦虑的发病机制或治疗有影响,这取决于饮食质量。虽然食物、特定营养物质和营养保健品影响心理健康的生物学机制尚不完全清楚,但涉及的途径包括炎症、氧化应激、大脑可塑性效应、线粒体功能障碍和神经递质代谢。必需的饮食微量矿物质,如锌、铜、铁和硒是许多生物蛋白质的关键成分,可能在这些与大脑健康和焦虑相关的机制中发挥作用。本文以最新的同行评议的科学证据为基础,探讨了必需微量元素锌、铜、铁和硒对焦虑症状的影响。目前的研究表明,锌、铁和硒的缺乏与焦虑有关,而铜超载可能比铜缺乏对焦虑的影响更大。需要进一步的研究来了解具体的神经生物学机制。总的来说,这些集体发现证明了优化微量矿物质稳态对于减轻焦虑症和保持心理健康的重要性。
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引用次数: 2
Factors Influencing Dietetic Interns’ Dietary Habits during Supervised Practice 影响实习营养师饮食习惯的因素
Pub Date : 2023-02-08 DOI: 10.3390/dietetics2010007
Courtney Weese, Katie M. Thompson, Adalyn White, Brianne Oronoz, Karli Breinholt, Dawson V. Croxall, Kelzie Devitt, Marin Easton, Madison L. Gunter, Breann McFarlane, Kaitlyn Reich, Jenna Sacks, Lacie Peterson, Rebecca Charlton, Holly Hopkins, Katie N. Kraus
Supervised practice is a prerequisite to becoming a registered dietitian. Research suggests that environmental and social factors may affect dietary choices. This focus group research aimed to gather opinions from dietetic interns to understand what factors related to supervised practice, if any, affected their dietary habits. Qualitative data were collected via seven recorded virtual focus groups in which trained moderators facilitated a discussion using a series of controlled questions. Participants, dietetic interns (n = 42) who were currently completing or had completed their supervised practice within the previous six months, attended one of seven virtual focus groups. Each focus group had five to eight participants. Transcripts were separately coded by two trained researchers using a grounded theory approach to identify themes and subthemes. Researchers discussed any disagreements in coding and established a consensus. Elements related to the dietetic internship were observed to influence participants’ dietary choices. Main themes included time, finances, food access and availability, physical and mental effects, non-supervised practice factors, and social factors. Dietetic programs and preceptors should explore ways to raise interns’ awareness and minimize the potential negative impacts of these factors on interns’ dietary habits to improve their overall internship experience.
有监督的实践是成为注册营养师的先决条件。研究表明,环境和社会因素可能会影响饮食选择。这项焦点小组研究旨在收集饮食实习生的意见,以了解与监督实践相关的因素,如果有的话,影响他们的饮食习惯。定性数据通过七个记录的虚拟焦点小组收集,其中训练有素的主持人通过一系列控制问题促进讨论。参与者,饮食实习生(n = 42),目前正在完成或在过去六个月内完成了他们的监督实践,参加了七个虚拟焦点小组中的一个。每个焦点小组有五到八名参与者。转录分别编码由两个训练有素的研究人员使用接地理论的方法来确定主题和次主题。研究人员讨论了编码中的任何分歧,并达成了共识。与营养学实习相关的因素被观察到影响参与者的饮食选择。主要主题包括时间、财务、食物获取和可用性、身体和精神影响、无监督的实践因素和社会因素。饮食项目和辅导员应想方设法提高实习生的意识,尽量减少这些因素对实习生饮食习惯的潜在负面影响,以改善实习生的整体实习体验。
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引用次数: 0
Survey of Australian Dietitians Contemporary Practice and Dietetic Interventions in Overweight and Obesity: An Update of Current Practice 澳大利亚营养师对超重和肥胖的当代实践和饮食干预的调查:当前实践的更新
Pub Date : 2023-02-01 DOI: 10.3390/dietetics2010006
E. Clarke, Rebecca L. Haslam, J. Baldwin, T. Burrows, L. Ashton, C. Collins
The aim of this survey was to identify, (1) use of Dietitians Australia best practice guidelines, (2) contemporary practices/knowledge, and (3) professional development needs of Australian dietitians in relation to management of clients with overweight or obesity. A cross-sectional online survey consisting of 67 multiple choice and Likert scale questions on the three survey aims was administered. Data were collected between 2020–2021 and reported descriptively as frequency (%). Of 178 survey attempts, 80 respondents completed all questions (45%). Most respondents spent >50% of their time working with individuals with overweight/obesity, usually in private practice (47%). Two thirds of respondents had accessed best practice guidelines, but only 12% had completely read best practice guidelines. General healthy eating was the most frequent dietary approach used (77%). Seventy-five percent (n = 56) of dietitians reported that dietary interventions were selected based on client preference. Almost half of dietitians rated their knowledge and level of skill in management of obesity as good. Approximately 60% (n = 41) dietitians reported their skill gap was related to providing behavioural therapy/counselling. Results of the current survey indicate that use of best practice guidelines is low. However, dietitians surveyed reported that they had a good understanding of obesity management and choose a client centred approach to management, which is in line with current recommendations. Professional development activities, particularly regarding behavioural counselling are of particular interest to dietitians working with individuals with obesity.
本次调查的目的是确定(1)澳大利亚营养师最佳实践指南的使用,(2)当代实践/知识,以及(3)澳大利亚营养师在超重或肥胖客户管理方面的专业发展需求。横断面在线调查由67个选择题和李克特量表问题组成,涉及三个调查目标。数据收集于2020-2021年,描述性报告频率(%)。在178次调查中,80名受访者完成了所有问题(45%)。大多数受访者将50%的时间用于治疗超重/肥胖患者,通常是在私人诊所(47%)。三分之二的受访者访问了最佳实践指南,但只有12%的受访者完全阅读了最佳实践指南。一般健康饮食是最常用的饮食方式(77%)。75% (n = 56)的营养师报告说,饮食干预是根据客户偏好选择的。几乎一半的营养师认为他们在肥胖管理方面的知识和技能水平是好的。大约60% (n = 41)的营养师报告他们的技能差距与提供行为治疗/咨询有关。目前的调查结果表明,最佳实践指南的使用率很低。然而,接受调查的营养师报告说,他们对肥胖管理有很好的理解,并选择以客户为中心的管理方法,这与目前的建议是一致的。专业发展活动,特别是关于行为咨询的活动,是与肥胖患者一起工作的营养师特别感兴趣的。
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引用次数: 0
Acknowledgment to the Reviewers of Dietetics in 2022 对2022年《营养学》评论家的致谢
Pub Date : 2023-01-20 DOI: 10.3390/dietetics2010005
High-quality academic publishing is built on rigorous peer review [...]
高质量的学术出版建立在严格的同行评审基础上〔…〕
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引用次数: 0
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Dietetics (Basel, Switzerland)
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