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Access to and predictors of substance use treatment and support among people experiencing incarceration in the United States: Analysis of a national cross-sectional study 在美国经历监禁的人中获得药物使用治疗和支持的途径和预测因素:一项全国性横断面研究的分析
Pub Date : 2025-06-01 Epub Date: 2025-05-08 DOI: 10.1016/j.dadr.2025.100343
Samuel J. Chen , Harold A. Pollack , Elizabeth M. Salisbury-Afshar , Mai T. Pho
Substance use-related overdose continues to be one of the leading causes of preventable death in the U.S. People returning from prisons and jails are at heightened risk. Certain substance use treatment methods in carceral facilities – especially medication for opioid use disorder (MOUD) – have shown promise in reducing overdose rates. Treatment availability has been under-studied, with past research often measuring whether facilities offer treatment, but not whether individuals actually receive it. This study used individual-level data to characterize who qualifies for prison-based treatment, who receives it, and what factors affect one’s likelihood of being treated, drawing from the most recent nationally-representative U.S. Survey of Prison Inmates. Descriptive statistics indicate that people with substance use disorder (SUD) who entered American prisons from 2014 to 2016 had lower levels of educational attainment, employment and housing, and higher levels of physical and mental illness. Just 13 % of individuals with SUD received any form of substance use treatment in prison; pharmacotherapies like methadone were almost nonexistent (<1 %). In controlled analysis, individuals who self-identified as Non-Hispanic Black or Hispanic had lower odds of receiving any treatment or support compared to Non-Hispanic White individuals. People convicted of a violent offense had lower odds of treatment than those convicted of other classes of crimes. These novel findings indicate that, in 2016, America’s prison-based substance use treatment had both poor accessibility and inequitable distribution. This raises concerns that, even as facility-level availability of modalities like MOUD continues to expand, certain groups may be left out without attention to individual-level availability.
在美国,与药物使用有关的过量使用仍然是导致可预防死亡的主要原因之一。从监狱和拘留所返回的人面临着更高的风险。在监狱设施中,某些物质使用治疗方法——特别是针对阿片类药物使用障碍(mod)的药物治疗——在降低过量吸毒率方面显示出了希望。治疗的可用性一直没有得到充分的研究,过去的研究通常衡量的是设施是否提供治疗,而不是个人是否真正接受治疗。这项研究使用了个人层面的数据来描述谁有资格接受监狱治疗,谁接受了治疗,以及哪些因素影响了一个人接受治疗的可能性,这些数据来自最近具有全国代表性的美国监狱囚犯调查。描述性统计数据显示,2014年至2016年进入美国监狱的物质使用障碍(SUD)患者的受教育程度、就业和住房水平较低,身体和精神疾病水平较高。只有13%的SUD患者在监狱中接受过任何形式的药物使用治疗;美沙酮等药物治疗几乎不存在(1%)。在对照分析中,与非西班牙裔白人相比,自我认定为非西班牙裔黑人或西班牙裔的人接受任何治疗或支持的几率更低。被判暴力犯罪的人比被判其他类型犯罪的人得到治疗的几率更低。这些新发现表明,2016年美国基于监狱的药物使用治疗可及性差,分配不公平。这引起了人们的关注,即使像mod这样的设施级别的可用性继续扩大,某些群体可能会在没有关注个人级别可用性的情况下被排除在外。
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引用次数: 0
Assessment of the associative determinants of tolerance to the effects of cannabis extract on exploratory behavior in rats 对大麻提取物对大鼠探索性行为影响的耐受相关决定因素的评估
Pub Date : 2025-06-01 Epub Date: 2025-05-07 DOI: 10.1016/j.dadr.2025.100344
Felipe I. Varas , Gonzalo Miguez , Vanetza E. Quezada-Scholz , Esperanza Ibáñez-Jiménez , Camila Aguilar , Simón Ramírez , Jonathan Badilla , Felipe Alfaro , Francisca Bertin , Javier Bustamante , Rocío Angulo , José A. Fuentealba , Alvaro Vergés , Mario A. Laborda
Experimental evaluation of cannabis tolerance has lacked an associative learning approach, focusing primarily on physiological variables. The present study assessed acute effects, chronic tolerance, and contextual specificity, exploring a potential associative component underlying cannabis tolerance. Sixteen adult Sprague-Dawley rats of both sexes were assigned to two groups, one receiving vaporized administrations of cannabis and the other receiving the vehicle substance, in two different counterbalanced contexts. An initial measurement was performed to assess acute effects, followed by four measurements to evaluate the development of chronic tolerance, and a final measurement to test the context specificity of tolerance, comparing the responses to the usual administration context and a novel context. Ten behaviors were analyzed in an open field. Acute effects were observed in seven indicators, corresponding to greater exploration activity in the group that received the drug compared to the control group. In five of these, the data also showed the development of chronic tolerance to the effects of cannabis on exploration, which was indicated by a progressive decrease in exploratory activity in the drug group. However, no evidence of context specificity was found in any variables in which chronic tolerance was observed. We discuss factors that may be related to the lack of contextual specificity of cannabis tolerance. Together, our findings show that a single administration of cannabis induces acute effects, and repeated exposure leads to chronic tolerance, ultimately reducing exploratory behavior.
大麻耐受性的实验评估缺乏一种联想学习方法,主要关注生理变量。本研究评估了急性效应、慢性耐受性和上下文特异性,探索大麻耐受性的潜在关联成分。16只成年雄性大鼠被分为两组,一组接受蒸发的大麻,另一组接受载体物质,在两种不同的平衡环境中。初步测量用于评估急性效应,随后进行四次测量以评估慢性耐受性的发展,最后测量用于测试耐受性的环境特异性,比较常规给药环境和新环境的反应。在一个开阔的场地上分析十种行为。在七个指标中观察到急性效应,与对照组相比,接受药物治疗的组有更大的探索活动。在其中的五个实验中,数据还显示了对大麻对探索的影响的慢性耐受性的发展,这表明了药物组的探索活动逐渐减少。然而,在观察到慢性耐受性的任何变量中,没有发现上下文特异性的证据。我们讨论了可能与大麻耐受性缺乏上下文特异性相关的因素。总之,我们的研究结果表明,单次服用大麻会产生急性效应,反复接触会导致慢性耐受性,最终减少探索行为。
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引用次数: 0
A phase I pilot study of a mobile education tool for supporting pregnant women with opioid use disorder 支持阿片类药物使用障碍孕妇的流动教育工具的第一阶段试点研究
Pub Date : 2025-06-01 Epub Date: 2025-03-26 DOI: 10.1016/j.dadr.2025.100327
Ekaterina Burduli , Jessica Fitts Willoughby , Kaylee Paulsgrove , Anna Winquist , Sterling M. McPherson , Ron Kim Johnson , Hendrée E. Jones

Background

Perinatal opioid use disorder (OUD) and neonatal abstinence syndrome (NAS) require targeted interventions to address gaps in maternal education and support. Maternal involvement in non-pharmacological NAS care is essential for improving neonatal outcomes, yet many mothers lack accessible resources to manage NAS symptoms and to navigate social and healthcare challenges. Mobile health applications offer a promising solution, but few cater specifically to the needs of perinatal women with OUD.

Objective

We assessed the usability, acceptability, and feasibility of a new mobile educational tool for pregnant women with OUD, focusing on the perinatal period and NAS care.

Results

Six perinatal women with OUD (n = 1 pregnant, n = 5 postpartum; mean age 31) found the tool highly acceptable (modified CSQ-8 mean=28.8 out of 32) and usable (modified SUS mean=45.0 out of 50). Most were likely to use the tool during pregnancy and postpartum, citing improved preparedness for advocating for themselves, managing NAS, and navigating CPS. Feedback suggested expanding content on infant withdrawal medications.

Conclusions

This mobile tool shows promise in empowering perinatal women with OUD. Further research is needed to evaluate its impact on clinical and neonatal outcomes.
围产期阿片类药物使用障碍(OUD)和新生儿戒断综合征(NAS)需要有针对性的干预措施来解决孕产妇教育和支持方面的差距。产妇参与非药物NAS护理对改善新生儿结局至关重要,但许多母亲缺乏可获得的资源来管理NAS症状并应对社会和医疗挑战。移动保健应用程序提供了一个很有前途的解决方案,但很少有专门针对患有OUD的围产期妇女的需求。目的评估一种新型OUD孕妇移动教育工具的可用性、可接受性和可行性,重点关注围产期和NAS护理。结果围产期OUD患者6例(孕期1例,产后5例;平均年龄31岁)发现该工具高度可接受(修改后的CSQ-8平均=28.8 / 32)和可用(修改后的SUS平均=45.0 / 50)。大多数人可能在怀孕和产后使用该工具,理由是为自己宣传、管理NAS和导航CPS做好了更好的准备。反馈建议扩大婴儿戒断药物的内容。结论:该移动工具有望增强患有OUD的围产期妇女的权能。需要进一步的研究来评估其对临床和新生儿结局的影响。
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引用次数: 0
Protocol for a new family history of addiction density score to aid in the treatment of alcohol and substance use disorders 一个新的成瘾密度评分家族史的方案,以帮助治疗酒精和物质使用障碍
Pub Date : 2025-06-01 Epub Date: 2025-02-20 DOI: 10.1016/j.dadr.2025.100321
Jessica L. Bourdon , Jordan Wright , Sabrina Verdecanna , Mer W. Francis , Vivia V. McCutcheon

Background

While molecular and non-molecular genetic testing are the gold standard for assessing a person’s familial liability for substance use disorders, such testing is often inaccessible. Family history information collected at intake is an alternative, but tools to effectively utilize this information are excessively complex. The aims of the study are threefold: 1) Describe a protocol for the collection of family history in a thorough and straightforward manner. 2) Provide an algorithm to convert family history information to numerical scores. 3) Present the aggregated results from the pilot testing of the protocol.

Methods

All patients (N = 871) underwent a comprehensive assessment that included the family history protocol. Descriptive statistics, t-tests and Pearson Correlation were used to analyze the scores and determine key differences by demographic categories (sex/race/ethnicity/substance/age).

Results

The protocol asked patients four key questions about 1st and 2nd degree relatives while completing a family pedigree. Answers were transferred into an algorithm to output a score for each patient. This score took affectedness and relatedness of each family member into account. The average number of affected relatives was 5.24 (SD=3.17), and there were significant sex, race, and primary substance score differences.

Conclusions

This study provides the addiction field with a novel, freely available, and easily implementable family history protocol that has several potential clinical applications. While more research is needed, pilot results provide a valuable research tool, insight into a typical family history for those at an inpatient addiction treatment center, and steps toward closing the research-to-practice gap in this field.
虽然分子和非分子基因检测是评估一个人对物质使用障碍的家族责任的金标准,但这种检测通常是无法获得的。在入院时收集的家族史信息是另一种选择,但有效利用这些信息的工具过于复杂。本研究的目的有三个:1)以彻底和直接的方式描述一种收集家族史的方案。2)提供一种将家族史信息转换为数值分数的算法。3)提出方案试点测试的汇总结果。方法所有患者(N = 871)接受了包括家族史方案在内的综合评估。使用描述性统计、t检验和Pearson相关性分析得分,并根据人口统计类别(性别/种族/民族/物质/年龄)确定关键差异。结果该方案在完成家庭系谱的同时,询问了患者关于一级和二级亲属的四个关键问题。答案被转移到一个算法中,为每个病人输出一个分数。这个分数考虑了每个家庭成员的情感和亲缘关系。患病亲属的平均人数为5.24人(SD=3.17),性别、种族和主要物质评分存在显著差异。结论:本研究为成瘾领域提供了一种新颖、免费、易于实施的家族史方案,具有多种潜在的临床应用价值。虽然需要更多的研究,但试点结果提供了一个有价值的研究工具,为住院成瘾治疗中心的患者提供了一个典型的家族史,并为缩小这一领域的研究与实践差距迈出了一步。
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引用次数: 0
Receipt of medications for opioid use disorder among rural and urban veterans health administration patients 农村和城市退伍军人卫生管理患者阿片类药物使用障碍的药物接收情况。
Pub Date : 2025-03-01 Epub Date: 2024-12-14 DOI: 10.1016/j.dadr.2024.100311
Olivia C. Reynolds , Kathleen F. Carlson , Adam J. Gordon , Robert L. Handley , Benjamin J. Morasco , Todd P. Korthuis , Travis I. Lovejoy , Jessica J. Wyse

Aim

We examined differences in medications for opioid use disorder (MOUD) receipt between rural and urban veteran patients following initiatives within the US Department of Veterans Affairs (VA) to expand access to MOUD.

Methods

Data for this retrospective cohort study were obtained from the VA Corporate Data Warehouse, which contains national electronic health record data for all VA patients. The analytic sample included all patients diagnosed with OUD from 10/1/2018–9/30/20. Rurality was identified by the Rural Urban Commuting Area (RUCA) code of patients’ home address. Associations between rurality and MOUD receipt, as well as type of MOUD received, were examined using logistic regression.

Results

Among 66,842 patients with OUD, 27.4 % were rural residents. Compared to urban patients, rural patients were slightly younger (50.1 vs. 52.5 years), more often white (87.7 % vs. 70.3 %) and less often received MOUD (42.6 % vs 45.5 %). Multivariable models confirmed that rural patients had a lower likelihood of accessing any form of MOUD (aOR= 0.84, 95 % CI: 0.81–0.87) relative to urban VA patients. Medication-specific analyses identified a lower likelihood of receiving methadone (aOR= 0.36, 95 % CI: 0.33–0.39) and naltrexone (aOR= 0.89, 95 % CI: 0.80–0.99) among rural patients, but higher likelihood of receiving buprenorphine (aOR= 1.05, 95 % CI: 1.01–1.09).

Conclusion

Rural VA patients have a lower likelihood of receiving methadone and naltrexone for OUD treatment relative to urban patients, but greater likelihood of receiving buprenorphine. Continued work is needed to ensure that rural Veterans have equitable access to the most appropriate medication for their health care needs.
目的:在美国退伍军人事务部(VA)扩大获得阿片类药物使用障碍(mod)的倡议之后,我们研究了农村和城市退伍军人患者在阿片类药物使用障碍(mod)收据方面的差异。方法:这项回顾性队列研究的数据来自VA公司数据仓库,该仓库包含所有VA患者的国家电子健康记录数据。分析样本包括2018年1月10日至20年9月30日期间诊断为OUD的所有患者。农村以患者家庭住址的农村城市通勤区(RUCA)编码进行识别。使用逻辑回归检验了乡村性与mod接收以及mod接收类型之间的关联。结果:66,842例OUD患者中,27.4%为农村居民。与城市患者相比,农村患者略年轻(50.1岁对52.5岁),白人患者较多(87.7%对70.3%),接受mod治疗的患者较少(42.6%对45.5%)。多变量模型证实,与城市VA患者相比,农村患者获得任何形式mod的可能性较低(aOR= 0.84, 95% CI: 0.81-0.87)。药物特异性分析发现,农村患者接受美沙酮(aOR= 0.36, 95% CI: 0.33-0.39)和纳曲酮(aOR= 0.89, 95% CI: 0.80-0.99)的可能性较低,但接受丁丙诺啡的可能性较高(aOR= 1.05, 95% CI: 1.01-1.09)。结论:与城市患者相比,农村VA患者接受美沙酮和纳曲酮治疗OUD的可能性较低,但接受丁丙诺啡的可能性较高。需要继续开展工作,确保农村退伍军人能够公平地获得最适合其保健需求的药物。
{"title":"Receipt of medications for opioid use disorder among rural and urban veterans health administration patients","authors":"Olivia C. Reynolds ,&nbsp;Kathleen F. Carlson ,&nbsp;Adam J. Gordon ,&nbsp;Robert L. Handley ,&nbsp;Benjamin J. Morasco ,&nbsp;Todd P. Korthuis ,&nbsp;Travis I. Lovejoy ,&nbsp;Jessica J. Wyse","doi":"10.1016/j.dadr.2024.100311","DOIUrl":"10.1016/j.dadr.2024.100311","url":null,"abstract":"<div><h3>Aim</h3><div>We examined differences in medications for opioid use disorder (MOUD) receipt between rural and urban veteran patients following initiatives within the US Department of Veterans Affairs (VA) to expand access to MOUD.</div></div><div><h3>Methods</h3><div>Data for this retrospective cohort study were obtained from the VA Corporate Data Warehouse, which contains national electronic health record data for all VA patients. The analytic sample included all patients diagnosed with OUD from 10/1/2018–9/30/20. Rurality was identified by the Rural Urban Commuting Area (RUCA) code of patients’ home address. Associations between rurality and MOUD receipt, as well as type of MOUD received, were examined using logistic regression.</div></div><div><h3>Results</h3><div>Among 66,842 patients with OUD, 27.4 % were rural residents. Compared to urban patients, rural patients were slightly younger (50.1 vs. 52.5 years), more often white (87.7 % vs. 70.3 %) and less often received MOUD (42.6 % vs 45.5 %). Multivariable models confirmed that rural patients had a lower likelihood of accessing any form of MOUD (aOR= 0.84, 95 % CI: 0.81–0.87) relative to urban VA patients. Medication-specific analyses identified a lower likelihood of receiving methadone (aOR= 0.36, 95 % CI: 0.33–0.39) and naltrexone (aOR= 0.89, 95 % CI: 0.80–0.99) among rural patients, but higher likelihood of receiving buprenorphine (aOR= 1.05, 95 % CI: 1.01–1.09).</div></div><div><h3>Conclusion</h3><div>Rural VA patients have a lower likelihood of receiving methadone and naltrexone for OUD treatment relative to urban patients, but greater likelihood of receiving buprenorphine. Continued work is needed to ensure that rural Veterans have equitable access to the most appropriate medication for their health care needs.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100311"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cannabis use and alcohol-related outcomes among sober living house residents with alcohol use disorders 有酒精使用障碍的清醒生活屋居民的大麻使用和酒精相关结果
Pub Date : 2025-03-01 Epub Date: 2024-12-12 DOI: 10.1016/j.dadr.2024.100312
Meenakshi S. Subbaraman , Elizabeth Mahoney , Amy Mericle , Douglas Polcin

Background

Evidence supporting cannabis substitution along with liberalized cannabis laws have left recovery homes such as sober living houses (SLHs) in a difficult position regarding policies relating to cannabis use among SLH residents. Moreover, there are few studies of cannabis use among SLH residents that can be used to inform cannabis use policies. Here we assess whether cannabis is related to alcohol use among SLH residents.

Methods

Data came from N = 205 SLH residents entering 28 SLHs in Los Angeles from 2021 to 2023. Interviews were at baseline and one-, two-, three-, and six-month follow-ups. All participants reported lifetime alcohol use disorder (AUD). The primary predictor was any past 30-day cannabis use. Past 30-day outcomes were any drinking, number of drinking days, and any alcohol problems. Longitudinal generalized estimating equation models tested associations between any past-30-day cannabis use and outcomes, adjusting for demographics, treatment, 12-step attendance, social network use, baseline drug use, and AUD severity.

Results

After adjustment for demographics and covariates, any past-30-day cannabis use was related to 7.02 times higher odds of any past 30-day drinking (OR=7.02, 95 % CI: 3.06, 16.12), 2.03 times more drinking days (IRR=2.03, 95 % CI: 1.01, 4.08), and 3.21 times higher odds of any past-30-day alcohol problems (OR=3.21, 95 % CI: 1.68, 6.14) vs. no past-30-day cannabis use.

Conclusions

Cannabis use is positively correlated with alcohol use and related problems in a sample of sober living house residents in Los Angeles.
背景:支持大麻替代的证据以及大麻法律的自由化使康复之家,如清醒生活之家(SLHs)在SLH居民中使用大麻的政策方面处于困难地位。此外,很少有关于SLH居民大麻使用的研究可以用来为大麻使用政策提供信息。在这里,我们评估大麻是否与SLH居民的酒精使用有关。方法:数据来自2021 - 2023年洛杉矶28家SLH的205名SLH居民。访谈是在基线和1个月、2个月、3个月和6个月的随访。所有参与者都报告了终生酒精使用障碍(AUD)。主要的预测因素是任何超过30天的大麻使用。过去30天的结果包括任何饮酒、饮酒天数和任何酒精问题。纵向广义估计方程模型测试了任何过去30天的大麻使用与结果之间的关联,调整了人口统计学、治疗、12步出勤、社交网络使用、基线药物使用和AUD严重程度。结果:在对人口统计学和协变量进行调整后,过去30天使用大麻与过去30天饮酒的几率(OR=7.02, 95% CI: 3.06, 16.12)、饮酒天数(IRR=2.03, 95% CI: 1.01, 4.08)和过去30天饮酒问题的几率(OR=3.21, 95% CI: 1.68, 6.14)相关,前者比后者高7.02倍。结论:大麻使用与酒精使用及相关问题在洛杉矶清醒生活屋居民样本中呈正相关。
{"title":"Cannabis use and alcohol-related outcomes among sober living house residents with alcohol use disorders","authors":"Meenakshi S. Subbaraman ,&nbsp;Elizabeth Mahoney ,&nbsp;Amy Mericle ,&nbsp;Douglas Polcin","doi":"10.1016/j.dadr.2024.100312","DOIUrl":"10.1016/j.dadr.2024.100312","url":null,"abstract":"<div><h3>Background</h3><div>Evidence supporting cannabis substitution along with liberalized cannabis laws have left recovery homes such as sober living houses (SLHs) in a difficult position regarding policies relating to cannabis use among SLH residents. Moreover, there are few studies of cannabis use among SLH residents that can be used to inform cannabis use policies. Here we assess whether cannabis is related to alcohol use among SLH residents.</div></div><div><h3>Methods</h3><div>Data came from N = 205 SLH residents entering 28 SLHs in Los Angeles from 2021 to 2023. Interviews were at baseline and one-, two-, three-, and six-month follow-ups. All participants reported lifetime alcohol use disorder (AUD). The primary predictor was any past 30-day cannabis use. Past 30-day outcomes were any drinking, number of drinking days, and any alcohol problems. Longitudinal generalized estimating equation models tested associations between any past-30-day cannabis use and outcomes, adjusting for demographics, treatment, 12-step attendance, social network use, baseline drug use, and AUD severity.</div></div><div><h3>Results</h3><div>After adjustment for demographics and covariates, any past-30-day cannabis use was related to 7.02 times higher odds of any past 30-day drinking (OR=7.02, 95 % CI: 3.06, 16.12), 2.03 times more drinking days (IRR=2.03, 95 % CI: 1.01, 4.08), and 3.21 times higher odds of any past-30-day alcohol problems (OR=3.21, 95 % CI: 1.68, 6.14) vs. no past-30-day cannabis use.</div></div><div><h3>Conclusions</h3><div>Cannabis use is positively correlated with alcohol use and related problems in a sample of sober living house residents in Los Angeles.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100312"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of safer smoking supply distribution with participant encounters and naloxone distribution from syringe services programs: Findings from the National Survey of Syringe Services Programs in the United States 更安全的吸烟供应分配与参与者接触和注射器服务计划的纳洛酮分配的关联:来自美国注射器服务计划全国调查的结果。
Pub Date : 2025-03-01 Epub Date: 2024-12-31 DOI: 10.1016/j.dadr.2024.100317
Esther O. Chung , Sheila V. Patel , Lynn D. Wenger , Jamie L. Humphrey , Amang Sukasih , Ricky N. Bluthenthal , Hansel E. Tookes , Don C. Des Jarlais , Sara N. Glick , Paul A. LaKosky , Stephanie Prohaska , Laura Guzman , Alex H. Kral , Barrot H. Lambdin

Background

In response to the recent and growing shift from injecting heroin to smoking fentanyl, an increasing number of syringe services programs (SSPs) in the United States are distributing safer smoking supplies. There is a lack of research on whether safer smoking supply distribution is associated with increased SSP engagement and naloxone distribution from SSPs. Therefore, we aimed to assess predictors of safer smoking supply distribution by SSPs and estimate associations between safer smoking supply distribution and scale of harm reduction services.

Methods

We used cross-sectional data from the National Survey of Syringe Services Programs, which surveyed SSPs from March and August 2023 about services delivered in 2022. We examined factors associated with safer smoking supply distribution and estimated associations between smoking supply distribution and the number of participant encounters and naloxone doses distributed.

Results

Of the 429 SSPs included, 187 (44.1 %) distributed safer smoking supplies to participants. SSP organizational type, service delivery method, urbanicity, and regional Census divisions were associated with safer smoking supply distribution. Compared to SSPs that did not distribute safer smoking supplies, those that did reported more participant encounters (aRR=1.62, 95 % CI: 1.19–2.20) and naloxone doses distributed (aRR=1.26, 95 % CI: 0.91–1.74).

Conclusions

SSPs distributing safer smoking supplies had greater participant engagement and naloxone distribution. To maximize their full individual and population-level health benefits, SSPs should be supported technically, legally, and financially to implement safer smoking supply distribution for their participants.
背景:为了应对最近越来越多的从注射海洛因到吸食芬太尼的转变,美国越来越多的注射器服务项目(ssp)正在分发更安全的吸烟用品。缺乏关于更安全的吸烟供应分布是否与SSP参与和SSP纳洛酮分布增加有关的研究。因此,我们旨在通过ssp评估更安全的吸烟供应分布的预测因素,并估计更安全的吸烟供应分布与减少危害服务规模之间的关联。方法:我们使用了来自全国注射器服务项目调查的横断面数据,该调查从2023年3月到8月调查了ssp在2022年提供的服务。我们检查了与更安全的吸烟供应分布相关的因素,并估计了吸烟供应分布与参与者接触次数和纳洛酮剂量分布之间的关联。结果:在纳入的429家ssp中,187家(44.1%)向参与者分发了更安全的吸烟用品。SSP的组织类型、服务提供方式、城市化程度和区域普查区划与更安全的吸烟供应分布有关。与没有分发更安全的吸烟用品的ssp相比,那些有分发的ssp报告了更多的参与者接触(aRR=1.62, 95% CI: 1.19-2.20)和纳洛酮剂量分布(aRR=1.26, 95% CI: 0.91-1.74)。结论:ssp分发更安全的吸烟用品有更大的参与者参与和纳洛酮分发。为了最大限度地发挥其个人和人群水平的健康效益,ssp应在技术上、法律上和财政上得到支持,为其参与者实施更安全的吸烟供应分配。
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引用次数: 0
Adverse childhood experiences, resilience, and syringe services program attendance among persons who inject drugs in Northeast Georgia, USA: A mediation analysis 在美国乔治亚州东北部注射毒品的人中,不良的童年经历、恢复力和注射器服务项目的出勤率:一项中介分析。
Pub Date : 2025-03-01 Epub Date: 2024-12-10 DOI: 10.1016/j.dadr.2024.100309
Mohammad Rifat Haider , Samantha Clinton , Monique J. Brown , Nathan B. Hansen

Background

Syringe services programs (SSP) are evidence-based venues offering harm reduction services to persons who inject drugs (PWID), such as sterile syringes, STI/HIV testing, and linkage to care to decrease drug use-related morbidities and mortalities. Adverse childhood experiences (ACEs) have been linked with reduced resilience, while increased resilience can help PWID attend SSPs. This study examined the potential mediating role of resilience between ACEs and SSP attendance among PWID.

Methods

Data were collected from adult HIV-negative PWID in northeast Georgia, between February-December 2023 (N = 173). Data were collected on SSP attendance (Yes vs. No), resilience, and ACEs. Covariates included age, gender, sexual orientation, race/ethnicity, education, homelessness, HIV risk behavior, syringe sharing, syringe use frequency, and primary drug. Path analysis was performed using Stata 18.0.

Results

The majority of PWID were cisgender men (68.8 %), heterosexual (92.5 %), homeless (93.6 %), had HIV risk behavior (65.9 %), had high resilience (54.3 %), and had never attended SSP (64.2 %). The mean number of ACEs was 4.1 (SD=3.2). After adjusting for covariates, high resilience was positively associated with SSP attendance (β= 0.204; p = 0.005). ACEs were negatively associated with high resilience (β= −0.035 p = 0.005) and SSP attendance (β= −0.026; p = 0.034). ACEs had a significant indirect effect on SSP attendance through high resilience (β= −0.007; p = 0.044).

Conclusions

Results indicate that resilience may mediate the relationship between ACEs and SSP attendance among PWID. It is important to develop and implement trauma-informed and resilience-based interventions to address the mental and sexual health challenges of PWID with a history of ACEs.
背景:注射器服务规划(SSP)是为注射吸毒者(PWID)提供减少伤害服务的循证场所,如无菌注射器、性传播感染/艾滋病毒检测以及与护理联系,以降低与药物使用相关的发病率和死亡率。不良的童年经历(ace)与韧性降低有关,而增强的韧性可以帮助PWID参加ssp。本研究探讨了心理弹性在PWID中ace与SSP出勤率之间的潜在中介作用。方法:收集佐治亚州东北部地区2023年2月至12月期间hiv阴性PWID成年患者的数据(N = 173)。数据收集了SSP的出勤率(是vs.否)、恢复力和ace。协变量包括年龄、性别、性取向、种族/民族、教育程度、无家可归、艾滋病毒风险行为、共用注射器、注射器使用频率和主要药物。采用Stata 18.0进行通径分析。结果:PWID以男异性恋者居多(68.8%),异性恋者居多(92.5%),无家可归者居多(93.6%),有HIV危险行为者居多(65.9%),有高适应能力者居多(54.3%),未参加过SSP者居多(64.2%)。平均ace次数为4.1次(SD=3.2)。调整协变量后,高弹性与SSP出席率呈正相关(β= 0.204;p = 0.005)。ace与高弹性(β= -0.035 p = 0.005)和SSP出勤率(β= -0.026;p = 0.034)。ace通过高弹性对SSP出勤率有显著的间接影响(β= -0.007;p = 0.044)。结论:心理弹性可能在PWID患者的ace和SSP出席率之间起中介作用。重要的是制定和实施创伤知情和基于复原力的干预措施,以解决有ace历史的PWID的精神和性健康挑战。
{"title":"Adverse childhood experiences, resilience, and syringe services program attendance among persons who inject drugs in Northeast Georgia, USA: A mediation analysis","authors":"Mohammad Rifat Haider ,&nbsp;Samantha Clinton ,&nbsp;Monique J. Brown ,&nbsp;Nathan B. Hansen","doi":"10.1016/j.dadr.2024.100309","DOIUrl":"10.1016/j.dadr.2024.100309","url":null,"abstract":"<div><h3>Background</h3><div>Syringe services programs (SSP) are evidence-based venues offering harm reduction services to persons who inject drugs (PWID), such as sterile syringes, STI/HIV testing, and linkage to care to decrease drug use-related morbidities and mortalities. Adverse childhood experiences (ACEs) have been linked with reduced resilience, while increased resilience can help PWID attend SSPs. This study examined the potential mediating role of resilience between ACEs and SSP attendance among PWID.</div></div><div><h3>Methods</h3><div>Data were collected from adult HIV-negative PWID in northeast Georgia, between February-December 2023 (N = 173). Data were collected on SSP attendance (Yes vs. No), resilience, and ACEs. Covariates included age, gender, sexual orientation, race/ethnicity, education, homelessness, HIV risk behavior, syringe sharing, syringe use frequency, and primary drug. Path analysis was performed using Stata 18.0.</div></div><div><h3>Results</h3><div>The majority of PWID were cisgender men (68.8 %), heterosexual (92.5 %), homeless (93.6 %), had HIV risk behavior (65.9 %), had high resilience (54.3 %), and had never attended SSP (64.2 %). The mean number of ACEs was 4.1 (SD=3.2). After adjusting for covariates, high resilience was positively associated with SSP attendance (β= 0.204; p = 0.005). ACEs were negatively associated with high resilience (β= −0.035 p = 0.005) and SSP attendance (β= −0.026; p = 0.034). ACEs had a significant indirect effect on SSP attendance through high resilience (β= −0.007; p = 0.044).</div></div><div><h3>Conclusions</h3><div>Results indicate that resilience may mediate the relationship between ACEs and SSP attendance among PWID. It is important to develop and implement trauma-informed and resilience-based interventions to address the mental and sexual health challenges of PWID with a history of ACEs.</div></div>","PeriodicalId":72841,"journal":{"name":"Drug and alcohol dependence reports","volume":"14 ","pages":"Article 100309"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of age on brief motivational intervention for unhealthy alcohol use 年龄对不健康饮酒的短暂动机干预的影响。
Pub Date : 2025-03-01 Epub Date: 2024-12-15 DOI: 10.1016/j.dadr.2024.100313
Belina Rodrigues , Nicolas Bertholet , Jean-Bernard Daeppen , Jacques Gaume

Introduction

The influence of age on brief motivational interventions (BMI) effects remains unknown. In the present study, we explored whether change in alcohol consumption after BMI differs across age groups and whether these differences are reflected in motivational interviewing (MI) counsellor skills.

Method

Secondary analysis of a randomized controlled trial among emergency room (ER) patients screened for unhealthy alcohol consumption. Participants (N = 97, 80 % men, 18–21 y: 19.6 %, 22–29 y: 22.7 %, 30–49 y: 34.0 % and ≥50 y: 23.7 %) received a single BMI in the ER, which was coded using the MI Skills Code 2.0. Alcohol outcomes were measured at 12-month. First, we tested whether BMI effect varied by age group using negative binomial regression for weekly drinking consumption, and logistic regression for change to low-risk drinking. Second, MI counsellor skills (global ratings of empathy, MI spirit and acceptance, and percentages of open questions, complex reflections (CR) and MI-consistent behaviors) were examined through one-way ANOVA or Welch test.

Results

The 22–29 y group i) reported lower consumption at follow-up compared to the 30–49 y group (IRR=1.60, p = .04) and the ≥ 50 y group (IRR=1.67, p = .03), and ii) was more likely to change to low-risk drinking than the 18–21 y group (OR=11.25, p = .04). When comparing MI counsellor skills across age groups, higher empathy ratings (F(3,93)= 2.70, p = .05) and a higher percentage of CR (F(3,93)= 4.10, p = .009) were recorded for the 22–29 y group.

Conclusion

This exploratory study shows that BMI was associated with significantly better 12-month alcohol outcomes among patients aged 22–29 years, which corresponded with higher counsellor empathy ratings and percentage of CR.
年龄对短暂动机干预(BMI)效应的影响尚不清楚。在本研究中,我们探讨了不同年龄组BMI后饮酒的变化是否不同,以及这些差异是否反映在动机访谈(MI)咨询师技能中。方法:对筛查出不健康饮酒的急诊室(ER)患者的随机对照试验进行二次分析。参与者(N = 97, 80%男性,18-21岁:19.6%,22-29岁:22.7%,30-49岁:34.0%和≥50岁:23.7%)在急诊室接受单一BMI,使用MI技能编码2.0进行编码。在12个月时测量酒精的结果。首先,我们通过对每周饮酒量的负二项回归和对低风险饮酒变化的逻辑回归,检验了BMI效应是否因年龄组而异。其次,通过单因素方差分析或韦尔奇检验,检验心理咨询师的技能(共情、心理咨询精神和接受度的总体评分,以及开放性问题、复杂反思(CR)和心理咨询一致行为的百分比)。结果:与30-49岁组(IRR=1.60, p = 0.04)和≥50岁组(IRR=1.67, p = 0.03)相比,22-29岁组(i)在随访时报告的饮酒量较低(IRR=1.60, p = 0.04), ii)比18-21岁组更容易转变为低风险饮酒(OR=11.25, p = 0.04)。当比较不同年龄组的心理咨询师技能时,22-29岁年龄组的共情评分较高(F(3,93)= 2.70, p = 0.05), CR百分比较高(F(3,93)= 4.10, p = 0.009)。结论:本探索性研究表明,在22-29岁的患者中,BMI与12个月的酒精预后显著相关,这与更高的咨询师共情评分和CR百分比相对应。
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引用次数: 0
The feasibility of utilizing the open dynamic interaction network (ODIN) app to assess rEMA data across 30 days among those recovering from alcohol use disorders 利用开放动态交互网络(ODIN)应用程序评估酒精使用障碍恢复者30天内rEMA数据的可行性。
Pub Date : 2025-03-01 Epub Date: 2024-12-04 DOI: 10.1016/j.dadr.2024.100305
Dennis E. McChargue , Bilal Khan , Jessica Phelps , Patrick Duryea , Kimberly A. Tyler , Arthur Andrews , Ellie Reznicek , Lucy Napper , Mohamed Saad , Hsuan-Wei Lee
Preliminary data from a prospective micro-longitudinal study (30 days) that examined the co-evolution of return to use risk among people diagnosed with an alcohol use disorder (AUD) in residential substance treatment is presented. Data assessed the feasibility of using the open dynamic interaction network (ODIN) responsive ecological momentary assessment (rEMA). rEMA collected daily estimates on affect, urges, sober-support engagement, and use. The ODIN app administered twelve daily questions at established EMA times. GPS-identified sober support engagement and alcohol access exposure prompted additional questions. Of the eight hundred questions, most people answered 500 questions. Five-day estimates showed that 80 % of the participants answered between 80 and 100 questions (10–30 questions/day). The ODIN app acquired 95 % of GPS readings across 30 days (~288 GPS readings/day). Most were satisfied with the stability (84 %), look/feel (82 %), and ease of use (92 %) of the ODIN app. Participants also reported interest in longer assessments that prompted them to call a sponsor (85 %) or to use prevention skills (72 %). Preliminary findings show that the ODIN platform accurately and efficiently collects data amongst this population.
本文介绍了一项前瞻性微纵向研究(30天)的初步数据,该研究检查了在住院药物治疗中被诊断为酒精使用障碍(AUD)的人重返使用风险的共同演变。数据评估了开放式动态交互网络(ODIN)响应性生态瞬时评价(rEMA)的可行性。rEMA收集每天对影响、督促、清醒支持参与和使用的估计。ODIN应用程序在规定的EMA时间管理12个每日问题。gps识别的清醒支持参与和酒精接触引发了其他问题。在800个问题中,大多数人回答了500个问题。五天的估计显示,80%的参与者回答了80到100个问题(10-30个问题/天)。ODIN应用程序在30天内获得95%的GPS读数(~288个GPS读数/天)。大多数人对ODIN应用程序的稳定性(84%),外观/感觉(82%)和易用性(92%)感到满意。参与者还报告了对更长的评估的兴趣,这促使他们打电话给赞助商(85%)或使用预防技能(72%)。初步调查结果表明,ODIN平台准确有效地收集了这一人群的数据。
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引用次数: 0
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Drug and alcohol dependence reports
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