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Valorization of Sacha inchi (Plukenetia volubilis L.) press cake in functional beverage development: Comparative evaluation of high-pressure and thermal pasteurization 茶饼在功能饮料开发中的价值评价:高压和热巴氏灭菌的比较评价
Pub Date : 2025-12-01 Epub Date: 2025-09-20 DOI: 10.1016/j.focha.2025.101121
Sunantha Ketnawa , Vannita Vong , Jinhu Tian , Yukiharu Ogawa , Wirongrong Tongdeesoontorn , Natthawuddhi Donlao
This study investigates the valorization of Sacha inchi press cake meal (SPM), a nutrient-rich by-product, as a sustainable ingredient for functional plant-based beverages. The effects of conventional pasteurization (CP) at 85 °C for 5 minutes and high-pressure processing (HP) at 400, 500, and 600 MPa for 5 minutes on the nutritional, physicochemical, and microbial properties of SPM-based beverages were compared. The HP600-treated beverage retained higher carbohydrate (4.04 %, w.b.) and lipid content (0.67 %) compared to the CP-treated sample. Protein (4.28 %) and fiber (0.40%) were slightly reduced, but the HP600-treated beverage exhibited significantly higher dietary fiber content (2.65 %). After 7 days of storage at 5 ± 1 °C, HP600 also improved antioxidant activity, bioactive compound retention, and physical properties such as better color consistency and reduced sedimentation. Effective microbial reduction was observed in all HP-treated beverages, which remained microbiologically safe. FTIR analysis confirmed the retention of key functional groups. Sensory evaluation showed that the HP-treated beverage had a taste and texture comparable to commercial almond milk. These findings highlight the potential of non-thermal technologies to create clean-label, sustainable, and health-promoting beverages, aligning with sustainable food production goals.
本研究探讨了印度茶压榨饼粕(SPM)作为功能性植物性饮料的可持续成分的价值,SPM是一种营养丰富的副产品。比较了85°C常规巴氏灭菌(CP) 5分钟和400、500和600 MPa高压灭菌(HP) 5分钟对spm饮料营养、理化和微生物特性的影响。与cp处理的样品相比,hp600处理的饮料保留了更高的碳水化合物(4.04%,w.b.h)和脂质含量(0.67%)。蛋白质(4.28%)和纤维(0.40%)含量略有降低,但经hp600处理的饮料的膳食纤维含量显著提高(2.65%)。在5±1°C下保存7天后,HP600还提高了抗氧化活性,生物活性化合物的保留率,以及更好的颜色一致性和减少沉淀等物理性能。在所有hp处理的饮料中观察到有效的微生物减少,保持微生物安全。FTIR分析证实了关键官能团的保留。感官评价表明,经过hp处理的饮料的口感和质地与商业杏仁奶相当。这些发现突出了非热技术在创造清洁标签、可持续和促进健康的饮料方面的潜力,与可持续食品生产目标保持一致。
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引用次数: 0
Advancements in foodomics: Transformative applications in enhancing food processing, ensuring quality, safety, traceability, and verifying authenticity 食品组学的进展:在加强食品加工、确保质量、安全、可追溯性和真实性验证方面的变革性应用
Pub Date : 2025-12-01 Epub Date: 2025-10-18 DOI: 10.1016/j.focha.2025.101138
Eyasu Yohannis , Tilahun A. Teka , Markos Makiso Urugo
Foodomics is an emerging multidisciplinary field that applies omics technologies such as genomics, proteomics, metabolomics, transcriptomics, and nutrigenomics to improve the understanding of food composition, quality, safety, and traceability. This review highlights recent advances in analytical methods for assessing nutrient profiles, identifying contaminants, and verifying food authenticity. Case studies demonstrate the practical impact of Foodomics, including metabolomics for authenticating horse milk adulteration, proteomic profiling for tracing seafood species and dairy product origins, and transcriptomic approaches for monitoring flavonoid biosynthesis in seeds and nitrogen stress responses in apple plants. In cereal and fruit-based products, Foodomics has also been employed to assess processing impacts through volatile fingerprinting and enzyme activity profiling. Despite these successes, widespread adoption is limited by high costs, data complexity, and the need for advanced bioinformatics and technical expertise. The variability of food matrices and dynamic processing environments presents further analytical challenges. A more balanced view of the field is necessary, including critical evaluation of methodological limitations and reproducibility concerns. Future directions involve integrating omics data with technologies such as machine learning and blockchain to enhance predictive modeling and supply chain transparency. Advancements in portable and affordable platforms along with standardization of protocols will be essential for broader implementation, particularly in developing countries. Collaboration among researchers, industry, and regulators will be vital to establish clear regulatory frameworks and realize the full potential of Foodomics in improving food safety and public health outcomes.
食品组学是一个新兴的多学科领域,它应用基因组学、蛋白质组学、代谢组学、转录组学和营养基因组学等组学技术来提高对食品成分、质量、安全性和可追溯性的理解。本综述重点介绍了评估营养成分、识别污染物和验证食品真实性的分析方法的最新进展。案例研究展示了食品组学的实际影响,包括用于验证马奶掺假的代谢组学,用于追踪海鲜物种和乳制品来源的蛋白质组学分析,以及用于监测种子中类黄酮生物合成和苹果植物氮胁迫反应的转录组学方法。在谷物和水果产品中,食品组学也被用于通过挥发性指纹和酶活性分析来评估加工影响。尽管取得了这些成功,但由于成本高、数据复杂以及对先进生物信息学和技术专长的需求,广泛采用受到限制。食物基质的可变性和动态加工环境提出了进一步的分析挑战。有必要对该领域有一个更平衡的看法,包括对方法局限性和可重复性问题的批判性评价。未来的发展方向包括将组学数据与机器学习和区块链等技术相结合,以增强预测建模和供应链透明度。便携式和负担得起的平台的进步以及协议的标准化对于更广泛的实施至关重要,特别是在发展中国家。研究人员、行业和监管机构之间的合作对于建立明确的监管框架和实现食品组学在改善食品安全和公共卫生结果方面的全部潜力至关重要。
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引用次数: 0
Valorization of Sacha Inchi press cake: Technological advances, market, and regulatory considerations for sustainable food applications 印度压饼的价值增值:可持续食品应用的技术进步、市场和监管考虑
Pub Date : 2025-12-01 Epub Date: 2025-10-26 DOI: 10.1016/j.focha.2025.101151
Janet Wamuni Njoroge , Piyawan Phonphimai , Pantaree Khatmorn , Sunantha Ketnawa , Phetnumnuang Tonkla , Vannita Vong , Jaspreet Singh , Lovedeep Kaur , Natthawuddhi Donlao
Sacha Inchi (Plukenetia volubilis L.) press cake (SP), the nutrient-dense by-product of oil extraction, is rich in high quality proteins, essential fatty acids, and bioactive compounds. However, its use remains constrained by processing, regulatory and market acceptance barriers. This review summarizes recent advances in processing strategies to improve SP’s nutritional, functional, and sensory qualities. Physical treatments (dry/wet fractionation, steaming, autoclaving, roasting and extrusion) increase protein digestibility and solubility while reducing heat-stable antinutrients. Emerging methods, including high-pressure processing, high-pressure homogenization, ultrasonication, microwave treatment, electroconductivity (Ohmic/PEF), and cold plasma technologies enhance extractability and bioactivity while preserving sensitive compounds. Chemical and chemo-enzymatic approaches (e.g., alkaline soaking, cyclodextrin complexation) suppress flavor precursors, whereas enzymatic hydrolysis and fermentation improve bioactive peptide release, digestibility, and functionality. Functional additives (sweeteners, salts, polysaccharides, flavor enhancers) help mask bitterness, while paired with consumer-preferred flavors increase acceptance. Beyond processing, safety approvals (e.g., Thai FDA, EU novel food approval) and consumer perception on sensory, nutritional, and sustainability factors shape its market potential. Currently, SP shows potential across a wide range of food applications and its valorization supports sustainable protein supply chains. Future opportunities depend on integrating processing, safety, and regulatory strategies with consumer-driven innovation.
核桃榨汁饼(SP)是榨油过程中营养丰富的副产品,含有丰富的优质蛋白质、必需脂肪酸和生物活性化合物。然而,它的使用仍然受到加工、监管和市场接受障碍的限制。本文综述了近年来提高SP营养、功能和感官品质的加工策略的研究进展。物理处理(干湿分馏、蒸煮、高压灭菌、烘烤和挤压)提高蛋白质的消化率和溶解度,同时减少热稳定性抗营养物质。新兴的方法,包括高压处理、高压均质、超声、微波处理、电导率(欧姆/PEF)和冷等离子体技术,在保留敏感化合物的同时提高了可提取性和生物活性。化学和化学酶方法(如碱性浸泡、环糊精络合)抑制风味前体,而酶水解和发酵改善生物活性肽的释放、消化率和功能。功能性添加剂(甜味剂、盐、多糖、增味剂)有助于掩盖苦味,而与消费者喜欢的口味搭配,则会增加消费者的接受度。除了加工,安全批准(如泰国FDA、欧盟新食品批准)和消费者对感官、营养和可持续性因素的看法塑造了其市场潜力。目前,SP在广泛的食品应用中显示出潜力,其价值增值支持可持续的蛋白质供应链。未来的机遇取决于将加工、安全和监管战略与消费者驱动的创新相结合。
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引用次数: 0
Integration of ultrasound-assisted extraction and deep eutectic solvent for enhanced recovery of bioactive compounds: Innovative green approach 超声辅助萃取和深度共熔溶剂的结合,提高生物活性化合物的回收率:创新的绿色方法
Pub Date : 2025-12-01 Epub Date: 2025-11-17 DOI: 10.1016/j.focha.2025.101153
Monika Roy , Piyush Kashyap , Kshirod Kumar Dash , Rafeeya Shams , G.V.S. BhagyaRaj , Shaikh Ayaz Mukarram , Béla Kovács
The use of Deep Eutectic Solvents (DESs) in conjunction with advanced extraction techniques, such as ultrasound-assisted extraction (UAE), can significantly enhance the effectiveness, specificity, and environmental friendliness of extraction procedures. Ultrasound can induce cavitation and microstreaming in the DES, which facilitates the solvent's penetration of the matrix and the liberation of target compound from solid substrates. This augmented mass transfer can result in increased extraction yields and shorter extraction times compared to traditional approaches. DESs are environmentally friendly and sustainable alternatives to traditional solvents due to their ability to degrade naturally, low toxicity levels, and renewable constituents. This review analyzes the process of extracting bioactive compounds from agro-industrial food waste using eco-friendly solvents and the integration of UAE and DESs for their enhanced recovery. Additionally, it encompassed the utilization of UAE and DESs to enhance the beneficial properties of bioactive compounds, such as antioxidants, antimicrobials, and antibacterial agents, as well as the potential viability of using these emerging solvents with UAE for the extraction process. Therefore, by leveraging the distinctive characteristics of DESs and the mechanical impact of ultrasound, this combined method can transform the extraction process, enabling the creation of environmentally friendly and effective extraction methods for food processing.
深层共晶溶剂(DESs)与超声辅助提取(UAE)等先进提取技术相结合,可以显著提高提取过程的有效性、特异性和环境友好性。超声波可以在DES中诱导空化和微流,这有利于溶剂穿透基体,使目标化合物从固体基质中解放出来。与传统方法相比,这种增强的传质可以提高提取收率,缩短提取时间。由于其自然降解能力、低毒性水平和可再生成分,DESs是传统溶剂的环保和可持续替代品。本文综述了利用环保型溶剂从农业工业食品垃圾中提取生物活性化合物的工艺,以及阿联酋和DESs的结合提高其回收率的方法。此外,它还包括利用UAE和DESs来增强生物活性化合物的有益特性,如抗氧化剂、抗菌剂和抗菌剂,以及将这些新兴溶剂与UAE一起用于提取过程的潜在可行性。因此,通过利用DESs的独特特性和超声波的机械影响,这种组合方法可以改变提取过程,从而为食品加工创造环保有效的提取方法。
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引用次数: 0
Dietary energy, antioxidant molecules, nutritional and lifestyle determinants pointers of brain cancer 饮食能量,抗氧化分子,营养和生活方式决定因素脑癌的指标
Pub Date : 2025-12-01 Epub Date: 2025-10-03 DOI: 10.1016/j.focha.2025.101130
Joel Okpoghono , Clive Isioma Okonta , Godson Oseahumen Omoike , Patience Onakurhefe
Brain cancers have been identified to be the leading cause of premature death in developed countries. The aim of the review was to appraise the dietary energy, nutritional factors, antioxidants rich bioactive molecules and lifestyle in the prevention of brain tumor. The scientific articles used in this review were obtained from the SciELO, PubMed, Science Direct, and Google Scholar databases. The review utilized only articles that were published between 2011 and 2025. The outcome of the review indicated that proper nutritional habits and lifestyle factors can prevent 30–50 % of cancer types. A diet rich in vegetables and antioxidants (e.g., vitamins C and resveratrol) may protect against glioma. Maintaining a healthy body weight and engaging in daily physical activity appear to be important. To enhance and apprehend the relationship between selected factors and the prevalence of gliomas, larger clinical studies across global regions and cultural practices are required.
脑癌已被确定为发达国家过早死亡的主要原因。本综述的目的是评价膳食能量、营养因子、富含生物活性分子的抗氧化剂和生活方式对脑肿瘤的预防作用。本综述中使用的科学文章来自SciELO、PubMed、Science Direct和b谷歌Scholar数据库。该综述仅使用了2011年至2025年间发表的文章。审查的结果表明,适当的营养习惯和生活方式因素可以预防30 - 50%的癌症类型。富含蔬菜和抗氧化剂(如维生素C和白藜芦醇)的饮食可以预防神经胶质瘤。保持健康的体重和参与日常体育活动似乎很重要。为了加强和理解选定因素与胶质瘤患病率之间的关系,需要在全球地区和文化实践中进行更大规模的临床研究。
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引用次数: 0
Moringa-enriched sunflower oil: A novel approach to enhancing nutritional quality and oxidative stability 富含辣木的葵花籽油:一种提高营养品质和氧化稳定性的新方法
Pub Date : 2025-12-01 Epub Date: 2025-09-06 DOI: 10.1016/j.focha.2025.101109
Eugenia Kibasa, Victor Vicent, Leonard Rweyemamu
Sunflower oil extraction typically involves mechanical pressing and refining, which degrades essential nutrients such as tocopherols and carotenoids. This study explores the use of dried Moringa oleifera Lam leaves as a pressing aid to enhance yield, nutritional value, and oxidative stability. Dehulled sunflower seeds were blended with Moringa oleifera Lam leaves at varying ratios (97:03, 95:05, 92:08, 86:14, 78:22, and 70:30 (w/w) before mechanical pressing to obtain oil samples (MSO1−MSO6). Results showed that dehulling improved oil quality and reduced pressing efficiency due to lower fibre content. Nutritional analysis revealed a significant increase (p < 0.05) in β-carotene content, raising from 28.69 ± 0.01 mg/kg in MSO1 to 30.47 ± 0.16 mg/kg in MSO6, whereas α-tocopherol concentration decreased with increasing Moringa oleifera Lam proportions. Fatty acid profiling indicated an increase in monounsaturated fatty acids (MUFAs) accompanied by a corresponding decrease in polyunsaturated fatty acids (PUFAs) across all samples. Physicochemical properties, including peroxide, iodine, and acid values, remained within acceptable limits, with oxidative stability improving across the formulations. These findings indicate that incorporating Moringa oleifera Lam leaves during pressing enhances both the nutritional value and functional properties of sunflower oil. The study highlights the potential of Moringa oleifera Lam-enriched sunflower oil as a functional food ingredient, offering improved stability and nutrient retention.
葵花籽油的提取通常涉及机械压榨和精炼,这会降低生育酚和类胡萝卜素等必需营养素。本研究探讨了使用辣木干叶作为压榨剂来提高产量、营养价值和氧化稳定性。将去壳的葵花籽与辣木叶按不同比例(97:03、95:05、92:08、86:14、78:22和70:30 (w/w)混合,然后进行机械压榨,得到油样(MSO1−MSO6)。结果表明,脱壳改善了油品质量,但由于纤维含量降低而降低了压榨效率。营养分析显示,随着辣木添加量的增加,β-胡萝卜素含量显著增加(p < 0.05),从MSO1的28.69±0.01 mg/kg增加到MSO6的30.47±0.16 mg/kg,而α-生育酚含量则下降。脂肪酸分析表明,在所有样品中,单不饱和脂肪酸(MUFAs)的增加伴随着多不饱和脂肪酸(PUFAs)的相应减少。物理化学性质,包括过氧化物、碘和酸值,保持在可接受的范围内,整个配方的氧化稳定性得到改善。上述结果表明,在压榨过程中加入辣木叶可以提高葵花籽油的营养价值和功能特性。该研究强调了辣木油籽油作为一种功能性食品成分的潜力,提供了更好的稳定性和营养保留。
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引用次数: 0
Microcapsules carriers of phenolic extracts of Maclura tinctoria (L) D. Don ex steud with/without fish oil: potential additive in commercial aquafeeds 加/不加鱼油的黄颡鱼酚类提取物微胶囊载体:潜在的商业水产饲料添加剂
Pub Date : 2025-12-01 Epub Date: 2025-09-12 DOI: 10.1016/j.focha.2025.101101
H.A. González-Ocampo , J.S. Díaz , B.E. Lopez-Corona , N. Almaraz-Abarca , A. Luna-González , M. García-Ulloa
The carrier potential of microencapsules of Maclura tinctoria phenolic extracts (BE) (Pat. # MX386653B) mixed with fish oil (FO) was determined. The spray dry process produced three different FO concentrations microcapsules: T1 = BEMIC; T2 = BEFO25 (BS+FO 25 mL l-1), and T3 = BEFO5 (BS + FO 50 mL l-1). The significantly highest Total phenol content (TPC), total flavonoids (TFC), condensed tannins (TTC), AA., and FRAP resulted in BEFO05 (253.35 mgEGA g-1, 98.63 EQ g-1, and 99.49 mgECA g-1, 47.55 ± 1.04 mgEGA mL-1, and 7.1 ± 0.1 mgEAA, respectively). The three powders showed adequate physical properties for juvenile shrimp aquafeeds with small size and circular morphology, low water activity and moisture content, high hygroscopicity, bulk, packing, Carr index, and Hausner ratio. The high dissolution and wetting times (56 and 66 min, respectively) allow the microcapsules to resist being submerged in water for a sufficient amount of time before being ingested, preserving the chemical properties of both the phenolic compounds and the fish oil.
黄花楸酚类提取物(BE)微胶囊的载体电位。# MX386653B)与鱼油(FO)混合。喷雾干燥制得三种不同浓度的FO微胶囊:T1 = BEMIC;T2 = BEFO25 (BS+FO 25 mL -1), T3 = BEFO5 (BS+FO 50 mL -1)。其中总酚(TPC)、总黄酮(TFC)、缩合单宁(TTC)、AA含量最高。, FRAP结果为BEFO05(分别为253.35 mgEGA g-1、98.63 EQ g-1、99.49 mgEGA g-1、47.55±1.04 mgEGA mL-1、7.1±0.1 mgEAA)。这三种粉末具有体积小、形状圆、水活度低、含水率低、吸湿性、体积、包装、卡尔指数和豪斯纳比高的特点。高溶解和湿润时间(分别为56分钟和66分钟)使微胶囊在被摄入之前能够抵抗在水中浸泡足够长的时间,从而保留了酚类化合物和鱼油的化学性质。
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引用次数: 0
Valorisation of Citrus sinensis peel biomass into functional slice jam: Optimisation using central composite design and quality characterisation 柑橘果皮生物量转化为功能性切片果酱:利用中心复合设计和质量表征进行优化
Pub Date : 2025-12-01 Epub Date: 2025-09-14 DOI: 10.1016/j.focha.2025.101116
Wan Fatimah Wan Mohd Nowalid , Izzah Hayati Yahya , Hazrulrizawati Abd Hamid
The valorisation of agro-industrial waste aligns with sustainability efforts and supports innovation in functional food development. This study explores the conversion of Citrus sinensis peel waste into a nutrient-enriched, sliceable jam using Central Composite Design (CCD). A systematic analysis was conducted to determine the different concentrations of pectin and C. sinensis peel puree affecting the important quality parameters such as pH, hardness, moisture content, vitamin C, and total phenolic content (TPC). Thirteen experimental runs were conducted, and the responses were modelled using second-order polynomial equations. Post hoc comparisons using Tukey’s HSD confirmed significant differences (p < 0.05) among treatments, allowing the identification of the best-performing formulation. The optimised formulation, comprising 91.398 g of C. sinensis peel puree and 6.038 g of pectin, yielded a product with a nutrient-enriched of total phenolic content (24.378 mg GAE/g), vitamin C (1677.17 mg/100 g), an improved texture (96.37 mJ), moisture content (55.25%) and desirable acidity of pH 2.89. The findings highlighted the ability of C. sinensis peel waste to improve the nutritional quality and functionality of gel-based food products. This study presents an innovative strategy for creating sustainable and ready-to-eat jams supporting food waste reduction and the advancement of a more resilient food system.
农业工业废物的增值与可持续性努力相一致,并支持功能性食品开发的创新。本研究探讨了利用中心复合设计(CCD)将柑橘果皮废弃物转化为营养丰富、可切片的果酱。系统分析了不同浓度的果胶和果皮对果皮pH、硬度、水分、维生素C和总酚含量等重要品质参数的影响。进行了13次试验,并采用二阶多项式方程对响应进行了建模。使用Tukey的HSD进行事后比较,证实了治疗之间的显著差异(p < 0.05),从而确定了表现最佳的配方。优化后的果胶用量为91.398 g,果胶用量为6.038 g,产品的总酚含量为24.378 mg GAE/g,维生素C含量为1677.17 mg/100 g,质地改善(96.37 mJ),水分含量为55.25%,酸度为pH 2.89。研究结果表明,柑橘果皮废弃物具有改善凝胶食品营养质量和功能性的作用。本研究提出了一项创新战略,以创造可持续的即食果酱,支持减少食物浪费和推进更具弹性的粮食系统。
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引用次数: 0
An integrated investigation on taro vegetable (Colocasia gigantea Hook.f.) to ascertain its ethnomedicinal importance: insights into prospective phytochemicals regulating analgesic, antidiabetic, and cytotoxic actions 对芋头蔬菜(Colocasia gigantea Hook.f.)的综合研究,以确定其民族医学意义:对未来植物化学物质调节镇痛、抗糖尿病和细胞毒性作用的见解
Pub Date : 2025-12-01 Epub Date: 2025-09-19 DOI: 10.1016/j.focha.2025.101099
Safaet Alam , Fahmida Tasnim Richi , Bakul Akter , Md. Hemayet Hossain , Satyajit Roy Rony , Abdullah Hridoy , Mahathir Mohammad , Sayema Khanum , Md. Sadman Hasib , Ferdoushi Jahan
Colocasia gigantea Hook.f., locally known as ‘Kochu’ in Bangladesh, is an edible vegetable with multi-diversified health benefits. This study aimed to validate the traditional use of Colocasia gigantea as an analgesic, antidiabetic, and cytotoxic agent. In vitro brine shrimp lethality bioassay showed an LC50 of 2.49 µg/mL, expressing its cytotoxic candidacy. Besides, in vivo glucose-induced hypoglycemic test showed a 52.23% decrease in blood glucose level after 3 hours of extract administration at 200 mg/kg-b.w. dose. Again, in vivo analgesic activity test deciphered 40.70% and 53.48% inhibition of writhing at 200 and 400 mg/kg-b.w. doses respectively. Besides, phytochemical screening followed by GC-MS analysis revealed thirty-eight (38) notable phytochemical groups and different bioactive phytochemicals. During thermodynamic analysis, C1 and C37 demonstrated a deficient free energy of -1489.288 and -1237.529 Hartree, respectively. In orbital analysis, C14 demonstrated the most favorable HOMO energy level at -7.672 eV. In contrast, C16 exhibited the lowest LUMO energy value at -2.054 eV. The HOMO-LUMO energy gap varied across the compounds, with C14 displaying the smallest gap of 5.275 eV. Besides, molecular docking analysis showed high binding affinity for corresponding receptors ranging from -8.4 to -4.1 kcal/mol for identified compounds. ADME/T predictions also resulted in auspicious outcomes, indicating their safety and drug-likeliness profile.
Colocasia gigantea Hook.f。在孟加拉国当地被称为“Kochu”,是一种具有多种健康益处的可食用蔬菜。本研究旨在验证巨巨茶作为镇痛、抗糖尿病和细胞毒性药物的传统用途。体外盐水对虾致死性生物测定显示LC50为2.49µg/mL,表明其具有细胞毒性。体内糖致低血糖试验显示,以200 mg/kg-b.w给药3 h后,血糖水平下降52.23%。剂量。同样,体内镇痛活性试验表明,200和400 mg/kg-b.w对扭体的抑制率分别为40.70%和53.48%。剂量分别。此外,植物化学筛选和GC-MS分析发现了38个显著的植物化学基团和不同的生物活性植物化学物质。在热力学分析中,C1和C37分别表现出-1489.288和-1237.529 Hartree的自由能缺陷。在轨道分析中,C14在-7.672 eV表现出最有利的HOMO能级。C16的LUMO能值最低,为-2.054 eV。化合物的HOMO-LUMO能隙各不相同,C14的能隙最小,为5.275 eV。此外,分子对接分析表明,鉴定的化合物与相应受体的结合亲和力在-8.4 ~ -4.1 kcal/mol之间。ADME/T预测也带来了吉祥的结果,表明它们的安全性和药物可能性。
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引用次数: 0
Bioactive profiling of valorized yoghurt incorporated with dragon fruit peel powder using LC-MS metabolomics 用LC-MS代谢组学分析添加火龙果皮粉的酸奶的生物活性
Pub Date : 2025-12-01 Epub Date: 2025-10-26 DOI: 10.1016/j.focha.2025.101156
Nyato Riba , Manish Kumar Singh , Dinesh Chandra Rai , Shankar Lal
Foodomics have emerged as an intriguing tool for the identification of the functional components in different fermented foods. Meanwhile, utilization of fruit processing waste for the development of composite dairy products has also become popular in the food industry. The present study delineates with the optimization of valorized yoghurt with incorporated dragon fruit peel powder (DPP) to enhance the functionality of the food. The formulation having 3% DPP was found best acceptable on the scale of sensory, textural and colour value analysis. The optimized yoghurt was showing total phenolic content of 405±2.66 mg GAE/100 g, total flavonoid content of 242±0.06 mg CE/100 g and antioxidant activity of 52.16% DPPH inhibition. Furthermore, an untargeted LC-MS omics have highlighted the presence of 34 major bioactive compounds with multifaceted functional properties. Linoleoyl glycerol, flaviolin, kaempferol coumarate, phenylacetylglycine, fatty acids, amino acids and many derivatives were covered in the metabolome in the RT range from 0.9 to 28 min. Numerous metabolites are known for their anti-inflammatory, anti-cancer, anti-CVD, anti-oxidant activities. This study has shown the enhanced bioactivity of the yoghurt post valorization which could confers a broad range of health benefits to the consumers. Additionally, functional composite foods can be developed utilizing processing waste and by-products to bring sustainability.
食品组学已经成为鉴定不同发酵食品中功能成分的一种有趣的工具。同时,利用水果加工废弃物开发复合乳制品也成为食品工业的热门。本研究对添加火龙果皮粉(DPP)的酸奶进行了优化,以提高食品的功能性。在感官、质地和颜色值分析上,发现含有3% DPP的配方是最可接受的。优化后的酸奶总酚含量为405±2.66 mg GAE/100 g,总黄酮含量为242±0.06 mg CE/100 g,抗氧化活性为52.16%,抑制DPPH。此外,非靶向LC-MS组学显示了34种具有多方面功能特性的主要生物活性化合物的存在。在0.9到28分钟的时间内,代谢组中包括了亚油酰甘油、黄拉酮、山奈酚香豆酸酯、苯乙酰甘氨酸、脂肪酸、氨基酸和许多衍生物。许多代谢物以其抗炎、抗癌、抗心血管疾病、抗氧化活性而闻名。这项研究表明,酸奶在发酵后的生物活性增强,可以给消费者带来广泛的健康益处。此外,可以利用加工废物和副产品开发功能性复合食品,以实现可持续性。
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Food chemistry advances
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