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Glucose and insulin levels’ linkages with breast cancer factors 葡萄糖和胰岛素水平与乳腺癌因素的关系
Pub Date : 2022-03-29 DOI: 10.17352/2455-8583.000057
Das Mahashweta, Saha Ishita, Sinha Prasenjit, Medda Sunit Kumar, Das Rabindra Nath
Serum lipid and glucose metabolisms are considered as the intermediary mechanisms for connecting obesity and Breast Cancer (BC). The article aims to identify the linkages between diabetes biochemical factors such as glucose & insulin and BC biochemical factors such as Monocyte Chemoattractant Protein-1 (MCP-1), adiponectin, Homeostasis Model Assessment score Insulin Resistance (HOMA-IR), resistin, leptin. These objectives can be focused on the two separate statistical models of glucose & insulin based on the remaining factors. From the mean model of glucose, it is observed that mean glucose level is directly linked with BC women (P= 0.023), leptin (P<0.001), HOMA-IR (P<0.001), while it is inversely linked with the interaction effects between HOMA-IR & leptin (i.e., HOMA-IR*leptin (P<0.001)) and adiponectin & leptin (i.e., adiponectin* leptin (P= 0.088)). Similarly, from the mean model of insulin, it is observed that mean insulin level is directly linked with HOMA-IR (P<0.001), leptin (P<0.001), and the interaction effects Age*MCP-1 (P= 0.091), glucose*adiponectin (P= 0.043), glucose*resistin (P<0.001), MCP-1*HOMA-IR (P<0.001), while it is reciprocally linked with MCP-1 (P= 0.026), resistin (P<0.001), adiponectin (P= 0.078), HOMA-IR*body mass index (BMI) (P<0.001), glucose*HOMA-IR (P<0.001), leptin*adiponectin (P= 0.071). There are more linkages of the variances of insulin and glucose with the BC biochemical factors. Based on the summarized results it is interpreted that diabetes biochemical factors such as insulin and glucose are highly linked with BC biomarkers such as MCP-1, HOMA-IR, leptin, resistin, and adiponectin.
血脂和葡萄糖代谢被认为是肥胖与乳腺癌(BC)之间的中介机制。本文旨在探讨糖尿病生化因子如葡萄糖、胰岛素与BC生化因子如单核细胞趋化蛋白-1 (MCP-1)、脂联素、稳态模型评估评分胰岛素抵抗(HOMA-IR)、抵抗素、瘦素之间的关系。这些目标可以集中在基于剩余因素的两个独立的葡萄糖和胰岛素统计模型上。从葡萄糖的平均模型可以看出,平均葡萄糖水平与BC女性(P= 0.023)、瘦素(P<0.001)、HOMA-IR (P<0.001)呈正相关,而与HOMA-IR与瘦素(即HOMA-IR*瘦素(P<0.001))、脂联素与瘦素(即脂联素*瘦素(P= 0.088))的相互作用呈负相关。同样,从胰岛素的平均模型可以看出,平均胰岛素水平与HOMA-IR (P<0.001)、瘦素(P<0.001)以及Age*MCP-1 (P= 0.091)、葡萄糖*脂联素(P= 0.043)、葡萄糖*抵抗素(P<0.001)、MCP-1*HOMA-IR (P<0.001)的交互作用直接相关,与MCP-1 (P= 0.026)、抵抗素(P<0.001)、脂联素(P= 0.078)、HOMA-IR*体重指数(BMI) (P<0.001)、葡萄糖*HOMA-IR (P<0.001)、瘦素*脂联素(P= 0.071)呈负相关。胰岛素和葡萄糖的差异与BC生化因子有更多的联系。综上所述,糖尿病生化因子如胰岛素和葡萄糖与BC生物标志物如MCP-1、HOMA-IR、瘦素、抵抗素和脂联素高度相关。
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引用次数: 0
Relationship between death anxiety and health-related quality of life among diabetic patients: The predictive roles of experiential avoidance 糖尿病患者死亡焦虑与健康相关生活质量的关系:体验回避的预测作用
Pub Date : 2022-01-27 DOI: 10.17352/2455-8583.000056
Ezaka Emmanuel Sochukwuma, Nassif Reyam Nehad, Chibuike Okoli Paul, Okeke Suhanya, Chukwubuzo Okpara Titus, Ekpunobi Chime Peter, Obumneme Ozougwu Augustine, Chinwike Okoli Alexander
This study investigated the predictive roles of experiential avoidance on the relationship between death anxiety and health-related quality of life among diabetic patients. A total of one hundred and five (105) participants (62; 58.5% females) participated in the study. The participant ages ranged from 21-75 years with a mean age of 53.45 and a standard deviation of 14.44. Participants were drawn using the convenience sampling technique and were administered the questionnaires before their consultations. Three instruments were used in data collation namely; the Death Anxiety Inventory-Revised (DAI-R), the Acceptance and Action Questionnaire (AAQ), and the Diabetes Quality of Life Questionnaire (DQOLQ). Four hypotheses were tested and the results showed that there was no significant correlation between death anxiety and HRQoL (r=-.036), also, experiential avoidance didn’t significantly predict HRQoL (.411, p<.05), experiential avoidance didn’t significantly predict death anxiety (.534, p<.05), while experiential avoidance didn’t predict the relationship between death anxiety and HRQoL (.757, p<.05). The researchers suggest that medical professionals in charge of diabetic patients should look beyond HRQoL and death anxiety in investigating whether there will be an occurrence of experiential avoidance.
本研究探讨经验回避对糖尿病患者死亡焦虑与健康相关生活质量关系的预测作用。共有105名参与者(62名;58.5%的女性)参与了这项研究。参与者年龄21 ~ 75岁,平均年龄53.45岁,标准差14.44岁。参与者采用方便抽样技术,并在咨询前进行问卷调查。数据整理使用了三种仪器,分别是;死亡焦虑量表修订(DAI-R)、接受与行动问卷(AAQ)和糖尿病生活质量问卷(DQOLQ)。对4个假设进行检验,结果显示死亡焦虑与HRQoL之间无显著相关(r=- 0.036),体验回避对HRQoL也无显著预测作用(r=- 0.036)。411, p< 0.05),经验回避对死亡焦虑无显著影响(p< 0.05)。534, p< 0.05),而经验回避不能预测死亡焦虑与HRQoL的关系(p< 0.05)。757年,p < . 05)。研究人员建议,负责糖尿病患者的医疗专业人员在调查是否会发生经验回避时,应超越HRQoL和死亡焦虑。
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引用次数: 1
COVID-19 and diabetes mellitus patients COVID-19与糖尿病患者
Pub Date : 2022-01-22 DOI: 10.17352/2455-8583.000055
Harsini Pooyan Afzali, Jeihooni Ali Khani, Imani Gholamreza, Hamzehie Saeed, Moghadam Hadis Safaei, Rozveh Fatemeh Alimohammadi, Alizadegan Sahar
Coronavirus (COVID-19) is an encapsulated virus with a self-positive-sense RNA genome that is proven to cause respiratory disease in humans. Coronaviruses (COVID-19) are a type of virus that infects the respiratory tract [1]. In most immunocompetent individuals, infection with human COVID-19 results in a moderate upper respiratory infection in the majority of cases.
冠状病毒(COVID-19)是一种具有自阳性RNA基因组的封装病毒,已被证明可引起人类呼吸道疾病。冠状病毒(COVID-19)是一种感染呼吸道的病毒[1]。在大多数免疫功能正常的个体中,大多数感染人COVID-19的病例会导致中度上呼吸道感染。
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引用次数: 0
Non adherence to physical activity recommendations and associated factors among Type 2 Diabetic patients in Illubabor zone, South West Ethiopia 埃塞俄比亚西南部Illubabor地区2型糖尿病患者不遵守体育锻炼建议及其相关因素
Pub Date : 2022-01-06 DOI: 10.17352/2455-8583.000054
Debalke Rukiya, Zinab Beakal, Belachew Tefera
Introduction: Diabetic patients’ poor adherence to lifestyle recommendations leads to poor glycemic control and associated micro and macro-vascular complications; however most patients have difficulty in adhering to the lifestyle modifications including physical activity recommendations. This study assessed the magnitude of non-adherence to physical activity recommendation and associated factors among type 2 diabetic patients attending follow up at government hospitals in Ilu Abba Bora Zone, southwestern Ethiopia. Methods: Institution based cross-sectional study was conducted from March 19 to May 19, 2018, among 422 diabetic patients attending regular follow up at government hospitals in Illuababor Zone, Southwest Ethiopia, participants were selected using systematic sampling method. Physical activity adherence was assessed using Global Physical Activity Questionnaire [GPAQ]. Multivariable logistic regression was used to identify factors associated with diabetic patients’ non-adherence to physical activity recommendations. Results: The study found that 38% of diabetic patients were non-adherent to physical activity recommendations. The odds non-adherence to physical activity recommendations was independently associated with patients’ sex (AOR=2 (95%CI:1.2, 3.4)), perceived severity of the illness (AOR=1.7 (95%CI:1.1, 2.8)) and self-efficacy (AOR=2.6 (95%CI:1.6,4.4)). Conclusion and recommendations: High proportions of diabetic patients were non-adherent to physical activity recommendations. Evidence based and Patient centered management plan should be practiced. The results imply that integrating lifestyle modification education focussing on physical activity recommendations should be integrated into diabetic care.
导论:糖尿病患者对生活方式建议的依从性较差,导致血糖控制不良和相关的微血管和大血管并发症;然而,大多数患者很难坚持生活方式的改变,包括体力活动的建议。本研究评估了在埃塞俄比亚西南部Ilu Abba Bora地区政府医院接受随访的2型糖尿病患者不遵守体育锻炼建议的程度及其相关因素。方法:对2018年3月19日至5月19日在埃塞俄比亚西南部Illuababor区政府医院定期随访的422例糖尿病患者进行基于机构的横断面研究,采用系统抽样方法选取参与者。使用全球身体活动问卷(GPAQ)评估身体活动依从性。采用多变量logistic回归来确定与糖尿病患者不遵守体育锻炼建议相关的因素。结果:研究发现,38%的糖尿病患者没有遵守体育锻炼建议。不遵守体育锻炼建议的几率与患者的性别(AOR=2 (95%CI:1.2, 3.4))、感知到的疾病严重程度(AOR=1.7 (95%CI:1.1, 2.8))和自我效能(AOR=2.6 (95%CI:1.6,4.4))独立相关。结论和建议:高比例的糖尿病患者不遵守体育锻炼建议。应实行循证、以患者为中心的管理方案。结果表明,以体育活动建议为重点的生活方式改变教育应纳入糖尿病护理。
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引用次数: 2
Lipid profile, abnormality of serum glucose levels and their associated factors in multidrug-resistant tuberculosis patients 耐多药结核病患者血脂、血糖异常及其相关因素分析
Pub Date : 2021-10-19 DOI: 10.17352/2455-8583.000053
Biranu Endalkchew, W. Mistire, Negesso Abebe Edao, Sisay Million Molla, Tola Habteyse Hailu
Background: The rise of multidrug-resistant tuberculosis (MDR-TB) has become a major public health concern around the world. Most patients with pulmonary tuberculosis have low body nutrients, hypocholesterolemia, and lower values were strongly associated with mortality in these patients. Representative data on lipid profile, fasting blood glucose abnormalities and their associated factors among MDR TB patients are lacking. Objective: To determine lipid profile, fasting blood glucose abnormalities and their associated factors among multi-drug resistant TB patients during therapy with anti-MDR-TB regimen in St.peter’s Specialized Hospital Addis Ababa, Ethiopia from January to November 2020. Methods and materials: A cross-sectional study was conducted among multi-drug resistant TB patients during MDR therapy regimen in St. Peter’s Specialized Hospital in Addis Ababa, Ethiopia from January to November 2020.Using the Consecutive sampling method a total of 162 blood samples was collected in SST tubes and analyzed by using the Cobas chemistry analyzer. Data were analyzed using SPSS software version 23 packages. Simple descriptive statistics were used to present the socio-demographic and clinical characteristics of the study participants. Other associations were performed with Pearson’s correlation coefficient. A p-value of <0.05 at the 95 % confidence level were considered as statistically significant in all the analyses. Results: Mean age of the study participant was 35.9 ± 13.6 years. The prevalence of diabetes was 16%. Out of those who had diabetes (9.8%) was newly diagnosed and 6.2% already knew their diabetes status.The most common serum lipid profile abnormalities were 92.6 % HDL-C and 35.8% had TG levels above the borderline. Among MDR-TB patients, 25.9% had a fasting blood glucose level that was higher than normal (hyperglycemic). Conclusion: Lipid profile abnormalities and an increased risk of diabetes have been observed in patients with multidrug-resistant tuberculosis. Factors associated with abnormal blood glucose needed attention to avoid further complications and also the finding of this research calls for the implementation of active case finding of DM in patients diagnosed for MDR-TB.
背景:耐多药结核病(MDR-TB)的上升已成为世界范围内一个主要的公共卫生问题。大多数肺结核患者都有低体内营养、低胆固醇血症,这些患者的低胆固醇值与死亡率密切相关。缺乏耐多药结核病患者的血脂、空腹血糖异常及其相关因素的代表性数据。目的:了解2020年1月至11月埃塞俄比亚亚的斯亚贝巴圣彼得专科医院耐多药结核病患者抗耐多药结核病方案治疗期间的血脂、空腹血糖异常及其相关因素。方法和材料:本研究于2020年1月至11月在埃塞俄比亚亚的斯亚贝巴圣彼得专科医院对耐多药治疗方案中的耐多药结核病患者进行了横断面研究。采用连续采血法,在SST管中采集162份血样,采用Cobas化学分析仪进行分析。数据分析采用SPSS软件23版软件包。使用简单的描述性统计来呈现研究参与者的社会人口学和临床特征。其他关联用Pearson相关系数进行。在95%置信水平下,p值<0.05被认为在所有分析中具有统计学意义。结果:研究参与者平均年龄为35.9±13.6岁。糖尿病患病率为16%。在糖尿病患者中(9.8%)是新诊断的,6.2%已经知道自己的糖尿病状况。最常见的血脂异常是92.6%的HDL-C和35.8%的TG水平高于临界值。在耐多药结核病患者中,25.9%的患者空腹血糖水平高于正常水平(高血糖)。结论:在耐多药结核病患者中观察到脂质异常和糖尿病风险增加。需要注意与血糖异常相关的因素,以避免进一步的并发症,并且本研究的发现要求在诊断为耐多药结核病的患者中实施积极的糖尿病病例发现。
{"title":"Lipid profile, abnormality of serum glucose levels and their associated factors in multidrug-resistant tuberculosis patients","authors":"Biranu Endalkchew, W. Mistire, Negesso Abebe Edao, Sisay Million Molla, Tola Habteyse Hailu","doi":"10.17352/2455-8583.000053","DOIUrl":"https://doi.org/10.17352/2455-8583.000053","url":null,"abstract":"Background: The rise of multidrug-resistant tuberculosis (MDR-TB) has become a major public health concern around the world. Most patients with pulmonary tuberculosis have low body nutrients, hypocholesterolemia, and lower values were strongly associated with mortality in these patients. Representative data on lipid profile, fasting blood glucose abnormalities and their associated factors among MDR TB patients are lacking. Objective: To determine lipid profile, fasting blood glucose abnormalities and their associated factors among multi-drug resistant TB patients during therapy with anti-MDR-TB regimen in St.peter’s Specialized Hospital Addis Ababa, Ethiopia from January to November 2020. Methods and materials: A cross-sectional study was conducted among multi-drug resistant TB patients during MDR therapy regimen in St. Peter’s Specialized Hospital in Addis Ababa, Ethiopia from January to November 2020.Using the Consecutive sampling method a total of 162 blood samples was collected in SST tubes and analyzed by using the Cobas chemistry analyzer. Data were analyzed using SPSS software version 23 packages. Simple descriptive statistics were used to present the socio-demographic and clinical characteristics of the study participants. Other associations were performed with Pearson’s correlation coefficient. A p-value of <0.05 at the 95 % confidence level were considered as statistically significant in all the analyses. Results: Mean age of the study participant was 35.9 ± 13.6 years. The prevalence of diabetes was 16%. Out of those who had diabetes (9.8%) was newly diagnosed and 6.2% already knew their diabetes status.The most common serum lipid profile abnormalities were 92.6 % HDL-C and 35.8% had TG levels above the borderline. Among MDR-TB patients, 25.9% had a fasting blood glucose level that was higher than normal (hyperglycemic). Conclusion: Lipid profile abnormalities and an increased risk of diabetes have been observed in patients with multidrug-resistant tuberculosis. Factors associated with abnormal blood glucose needed attention to avoid further complications and also the finding of this research calls for the implementation of active case finding of DM in patients diagnosed for MDR-TB.","PeriodicalId":73168,"journal":{"name":"Global journal of obesity, diabetes and metabolic syndrome","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87103755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Diabetes Mellitus: A stitch in time saves Nine Early Diagnosis and Management minimizes complications- A Case Study 糖尿病:及时一针可节省9个病例,早期诊断和治疗可减少并发症
Pub Date : 2021-08-10 DOI: 10.17352/2455-8583.000052
K. Akshay, K. Suresh
Diabetes mellitus is a group of metabolic diseases in which the person has high blood glucose level, either due to inadequate insulin secretion or because the body’s cells do not respond properly to the insulin or both.
糖尿病是一组代谢性疾病,患者的血糖水平较高,要么是由于胰岛素分泌不足,要么是由于身体细胞对胰岛素的反应不正常,或者两者兼而有之。
{"title":"Diabetes Mellitus: A stitch in time saves Nine Early Diagnosis and Management minimizes complications- A Case Study","authors":"K. Akshay, K. Suresh","doi":"10.17352/2455-8583.000052","DOIUrl":"https://doi.org/10.17352/2455-8583.000052","url":null,"abstract":"Diabetes mellitus is a group of metabolic diseases in which the person has high blood glucose level, either due to inadequate insulin secretion or because the body’s cells do not respond properly to the insulin or both.","PeriodicalId":73168,"journal":{"name":"Global journal of obesity, diabetes and metabolic syndrome","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89590046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The use of fenugreek supplementation in diabetes 胡芦巴补充剂在糖尿病中的应用
Pub Date : 2021-08-10 DOI: 10.17352/2455-8583.000051
Aamir Jalal Al-Mosawi
Sharma and colleagues (1990) reported that the use of defatted fenugreek seed powder in the treatment of in type I diabetes, in a dose of 100 g divided in two doses for ten days, was associated with a considerable lowering of fasting blood sugar and resulted in an improvement in the glucose tolerance test. They also found a 54% lowering of 24-hour urinary glucose excretion. Treatment also had an important lowering effect on serum total cholesterol, LDL and VLDL cholesterol and triglycerides were also signifi cantly reduced [6].
Sharma及其同事(1990)报道,使用脱脂胡芦巴籽粉治疗I型糖尿病,剂量为100 g,分两次服用,持续10天,可显著降低空腹血糖,并改善葡萄糖耐量试验。他们还发现24小时尿糖排泄量降低了54%。治疗对血清总胆固醇也有重要的降低作用,LDL和VLDL胆固醇及甘油三酯也显著降低[6]。
{"title":"The use of fenugreek supplementation in diabetes","authors":"Aamir Jalal Al-Mosawi","doi":"10.17352/2455-8583.000051","DOIUrl":"https://doi.org/10.17352/2455-8583.000051","url":null,"abstract":"Sharma and colleagues (1990) reported that the use of defatted fenugreek seed powder in the treatment of in type I diabetes, in a dose of 100 g divided in two doses for ten days, was associated with a considerable lowering of fasting blood sugar and resulted in an improvement in the glucose tolerance test. They also found a 54% lowering of 24-hour urinary glucose excretion. Treatment also had an important lowering effect on serum total cholesterol, LDL and VLDL cholesterol and triglycerides were also signifi cantly reduced [6].","PeriodicalId":73168,"journal":{"name":"Global journal of obesity, diabetes and metabolic syndrome","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89777578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Relationship between obesity and frailty in an old age population of Sindh, Pakistan 巴基斯坦信德省老年人口肥胖与虚弱的关系
Pub Date : 2021-07-24 DOI: 10.17352/2455-8583.000050
Kainat Faizan, Aadil Ali
Objective: To identify the Relationship between Obesity and Frailty in an old age Population of Sindh, Pakistan. Methodology: A cross sectional survey was conducted in many different hospitals of Karachi, Pakistan in December 2017. A self-constructed questionnaire was used which includes which includes the demographics, health status of patients, the Body Mass Index (BMI) and to analyze the data acquired, we used SPSS version 23. Results: 89.1% (n=339) of the participants belong to age group of 60-65 years and 57.3% (n=216) were male. Moreover, the Majority (n=183, 78.8%) of the participants reported with poor health status. After checking the level of Frailty among the participants, (n=218, 58%) of the participants were found to be frail. Conclusion: This Study concluded that there is significant impact of obesity on Frailty, because as the people ages the level of calcium and vitamin D in the bones decreases, bone become fragile and cannot support the increased weight of an individual which leads to weakness and susceptibility to disease.
目的:了解巴基斯坦信德省老年人群肥胖与虚弱的关系。方法:于2017年12月在巴基斯坦卡拉奇的多家不同医院进行了横断面调查。使用自编问卷,其中包括人口统计,患者的健康状况,身体质量指数(BMI),并分析获得的数据,我们使用SPSS版本23。结果:60 ~ 65岁年龄组占89.1% (n=339),男性占57.3% (n=216)。此外,大多数(n=183, 78.8%)的参与者报告健康状况不佳。在检查了参与者的虚弱程度后,(n=218, 58%)的参与者被发现虚弱。结论:本研究得出肥胖对虚弱有显著影响的结论,因为随着年龄的增长,骨骼中的钙和维生素D水平下降,骨骼变得脆弱,无法支撑个体增加的体重,从而导致虚弱和易患疾病。
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引用次数: 1
Clinical Features, Risk Factors and Hospital Mortality of Acute Stroke Patients 急性脑卒中患者的临床特征、危险因素及住院死亡率
Pub Date : 2020-09-21 DOI: 10.33805/2638-812x.121
M. Anwar, Sajeda Afrin, A. Mondol, Mohammad Nurul Islam Khan, Narayan Chandra Sarkar, Kamruzzaman Sarkar, Shahed Jahan, M. Rani, R. Mondal
Background: Stroke is a leading cause of mortality and disability worldwide. To prevent complications and permanent defects, early diagnosis, distinguishing the type and risk factor of stroke is crucial. Methodology: It was a hospital based cross sectional study, purposive sampling method was used, and a total of 469 stroke patients admitted into Department of Medicine, Rangpur medical college hospital, Bangladesh were included in this study. Results: In this study we have studied of 469 acute stroke patients. Among them 81% (380) were ischemic stroke patients and 19% (89) were hemorrhagic stroke. Overall male were more than female 308 (65.7%) vs 161(34.4%). The mean age for the ischemic stroke group was 64.1 ± 10.9 years, which was significantly higher than that of the hemorrhagic group (59.8 ± 9.60years) (P<0.05). Acute hemorrhagic stroke patients presented with acute onset of focal neurological deficit 61.8%, headache 64%, vomiting 59.6%, alteration of consciousness 48.3% and convulsion 27%. On the other hand, acute ischemic stroke patient presented with alteration of consciousness 65.5%, acute onset of focal neurological deficit 39.5%, paralysis 41%, deficit after awakening 32.4% and aphasia 34.7%. Among the risk factors of stroke in acute ischemic stroke patients hypertension was 59.2%, diabetes mellitus 20%, history of previous stroke 16.1%, ischemic heart disease 14.5% and atrial fibrillation 10.3% were present, on the other hand in acute hemorrhagic stroke patients hypertension 76.4%, smoking 70.8% and diabetes mellitus 6.7% were present. 26.97% of the acute hemorrhagic stroke and 13.9% of the acute ischemic stroke patients died in hospital. Conclusion: Common presentation of stroke was acute onset of focal neurological deficit; headache and vomiting were more in hemorrhagic stroke patient; alteration of consciousness, paralysis was predominant in ischemic stroke patient.
背景:中风是世界范围内导致死亡和残疾的主要原因。为了预防并发症和永久性缺陷,早期诊断、区分脑卒中的类型和危险因素至关重要。方法:采用医院为基础的横断面研究,采用有目的抽样方法,共纳入孟加拉国Rangpur医学院附属医院内科收治的469例脑卒中患者。结果:对469例急性脑卒中患者进行了研究。其中81%(380例)为缺血性脑卒中,19%(89例)为出血性脑卒中。总体上男性多于女性308人(65.7%)vs 161人(34.4%)。缺血性脑卒中组患者平均年龄为64.1±10.9岁,明显高于出血性脑卒中组(59.8±9.60岁)(P<0.05)。急性出血性卒中患者急性起病表现为局灶性神经功能缺损61.8%,头痛64%,呕吐59.6%,意识改变48.3%,惊厥27%。另一方面,急性缺血性脑卒中患者表现为意识改变65.5%,急性发作局灶性神经功能缺损39.5%,麻痹41%,醒后功能缺损32.4%,失语34.7%。急性缺血性脑卒中危险因素中高血压占59.2%,糖尿病占20%,既往卒中史占16.1%,缺血性心脏病占14.5%,心房颤动占10.3%,急性出血性脑卒中危险因素中高血压占76.4%,吸烟占70.8%,糖尿病占6.7%。26.97%的急性出血性卒中患者和13.9%的急性缺血性卒中患者在医院死亡。结论:卒中的常见表现为急性发作局灶性神经功能缺损;出血性卒中患者头痛、呕吐较多;缺血性脑卒中患者以意识改变、麻痹为主。
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引用次数: 0
Obesity, Diabetes, and Metabolic Syndrome 肥胖、糖尿病和代谢综合征
Pub Date : 2020-06-30 DOI: 10.17352/2455-8583.000045
Ghada Welwel
In the contemporary society, there are various health factors that affect people, both the elderly and the young population based on their environment and the interconnected risk factors. Based on that, it is necessary to understand and comprehend that metabolic syndrome also known as (Mets) involves a combination of risk factors for glucose intolerance, insulin resistance, obesity, dyslipidemia, as well as hypertension [1].
在当代社会,有各种各样的健康因素影响着人们,无论是老年人还是年轻人,这取决于他们所处的环境和相互关联的风险因素。基于此,有必要了解和理解代谢综合征(Mets)是葡萄糖耐受不良、胰岛素抵抗、肥胖、血脂异常、高血压等危险因素的综合[1]。
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引用次数: 0
期刊
Global journal of obesity, diabetes and metabolic syndrome
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