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Early bone health: exploring relationship between oxidative stress and skeletal development in newborn infants 早期骨骼健康:探索新生儿氧化应激与骨骼发育的关系
Pub Date : 2025-09-04 DOI: 10.1016/j.gpeds.2025.100292
Serafina Perrone , Laura Cannavò , Virginia Beretta , Elena Scarpa , Serena Benedetti , Chiara Petrolini , Vincenzo Raitano , Domenico Corica , Tommaso Aversa , Maria Cristina Albertini , Andrea Dall’Asta , Maria Elisabeth Street , Tullio Ghi , Silvia Carloni , Malgorzata Wasniewska
Bone health during childhood is critical for proper skeletal development and long-term quality of life. The process of bone formation relies on a balance of mineralization and cellular activity, which is regulated by oxidative stress (OS). While physiological levels of reactive oxygen species (ROS) are important for normal bone cell function and homeostasis, excessive OS can contribute to the development of bone diseases, such as osteoarthritis and osteoporosis. Enzymes like xanthine oxidoreductase are involved in amplifying ROS production, which can lead to cartilage degradation and disrupted bone remodeling. Despite increasing recognition of OS as a risk factor in adult skeletal health, its impact on fetal and neonatal bone development remains underexplored. In vitro and animal model studies, including those using free radicals exposure, have been performed to understand how OS impairs osteogenesis.
This review examines the role of OS in perinatal bone development analyzing key environmental risk factors and the potential long-term consequences of early-life redox imbalance on skeletal health.
The sensitivity of the fetal bone to OS suggests that oxidative damage during this critical period can result in impaired bone growth, low birth weight, and long-term skeletal disorders. Oxidative stress interferes with osteoblast differentiation, enhances adipocyte formation from mesenchymal stem cells, and stimulates osteoclast activity, leading to bone resorption. Clinical studies on the impact of OS on neonatal bone metabolism remain limited. Identifying key risk factors for early-life redox imbalance could be crucial in developing potential antioxidant therapies to support skeletal health during childhood
儿童时期的骨骼健康对骨骼发育和长期生活质量至关重要。骨形成过程依赖于矿化和细胞活动的平衡,这是由氧化应激(OS)调节的。虽然生理水平的活性氧(ROS)对正常骨细胞功能和体内平衡很重要,但过多的活性氧会导致骨疾病的发生,如骨关节炎和骨质疏松症。黄嘌呤氧化还原酶等酶参与放大ROS的产生,从而导致软骨降解和骨重塑中断。尽管越来越多的人认识到骨肉瘤是成人骨骼健康的危险因素,但其对胎儿和新生儿骨骼发育的影响仍未得到充分探讨。体外和动物模型研究,包括使用自由基暴露的研究,已经进行了了解OS如何损害成骨。本文综述了OS在围产期骨骼发育中的作用,分析了关键的环境危险因素以及早期氧化还原失衡对骨骼健康的潜在长期影响。胎儿骨骼对OS的敏感性表明,这一关键时期的氧化损伤可导致骨骼生长受损、低出生体重和长期骨骼疾病。氧化应激干扰成骨细胞分化,增强间充质干细胞形成脂肪细胞,刺激破骨细胞活性,导致骨吸收。关于OS对新生儿骨代谢影响的临床研究仍然有限。确定早期氧化还原失衡的关键风险因素对于开发潜在的抗氧化疗法以支持儿童时期的骨骼健康至关重要
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引用次数: 0
Coping strategies, anxiety and self-efficacy among participants in neonatal resuscitation courses for instructors 新生儿复苏指导课程参与者的应对策略、焦虑和自我效能感
Pub Date : 2025-09-03 DOI: 10.1016/j.gpeds.2025.100291
Francesca Saretta , Laura Polloni , Francesco Cavallin , Giuseppe De Bernardo , Paolo Ernesto Villani , Rossana Schiavo , Daniele Trevisanuto

Aim

To investigate coping strategies, anxiety and self-efficacy among participants in Neonatal Resuscitation Courses for instructors.

Methods

Cross-sectional study. Sixty-four participants in two Neonatal Resuscitation Courses for Instructors were assessed by using validated questionnaires.

Results

Overall, self-efficacy and functional coping strategies were moderate/high, while levels of anxiety were quite low. Self- efficacy was positively correlated with positive attitude (r = 0.29; p = 0.02) and problem solving (r = 0.44; p < 0.01) and inversely correlated with avoidance strategies (r=-0.30; p = 0.01) and anxiety (trait r=-0.47; p < 0.01; state r=-0.35; p = 0.01). Emotional maturity was positively correlated with positive attitude (r = 0.42; p < 0.01) and problem solving (r = 0.45; p < 0.01) and inversely correlated with anxiety (trait -0.51; p < 0.01; state r=-0.34; p = 0.01). Finalization of action was positively correlated with problem solving (r = 0.40; p < 0.01) and inversely correlated with avoidance strategies (r=-0.34; p = 0.01) and trait anxiety (r=-0.32; p = 0.01). Relational fluidity was positively correlated with turning to religion (r = 0.28; p = 0.03) and inversely correlated with avoidance strategies (r=-0.31; p = 0.01), and trait anxiety (r=-0.42; p < 0.01). Context analysis was positively correlated with problem solving (r = 0.34; p = 0.01) and inversely correlated with state anxiety (r=-0.36; p < 0.01). Problem solving was significantly higher in doctors compared to nurses (p = 0.01).

Conclusions

Neonatal resuscitation instructor candidates displayed high self-efficacy and functional coping strategies, with low anxiety levels. This may help professionals to better deal with stressful and demanding situations and reinforce adaptive work management.
目的探讨新生儿复苏指导课程参与者的应对策略、焦虑和自我效能感。MethodsCross-sectional研究。采用有效问卷对两门新生儿复苏课程的64名参与者进行评估。结果总体而言,自我效能感和功能性应对策略处于中高水平,焦虑水平较低。自我效能感与积极态度(r= 0.29; p = 0.02)和问题解决能力(r= 0.44; p < 0.01)呈正相关,与回避策略(r=-0.30; p = 0.01)和焦虑(特质r=-0.47; p < 0.01;状态r=-0.35; p = 0.01)呈负相关。情绪成熟度与积极态度(r = 0.42; p < 0.01)、问题解决能力(r = 0.45; p < 0.01)呈正相关,与焦虑(特质r= -0.51; p < 0.01;状态r=-0.34; p = 0.01)呈负相关。最终行动与问题解决呈正相关(r= 0.40; p < 0.01),与回避策略(r=-0.34; p = 0.01)和特质焦虑(r=-0.32; p = 0.01)呈负相关。关系流动性与宗教信仰正相关(r= 0.28; p = 0.03),与回避策略负相关(r=-0.31; p = 0.01),与特质焦虑负相关(r=-0.42; p < 0.01)。情境分析与问题解决能力呈正相关(r= 0.34; p = 0.01),与状态焦虑呈负相关(r=-0.36; p < 0.01)。医生解决问题的能力显著高于护士(p = 0.01)。结论新生儿复苏指导员候选人表现出较高的自我效能感和功能性应对策略,焦虑水平低。这可以帮助专业人士更好地处理压力和要求高的情况,并加强适应性工作管理。
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引用次数: 0
The unseen burden: Challenges by children and adolescents in witness protection programs in western countries 看不见的负担:西方国家儿童和青少年在证人保护项目中面临的挑战
Pub Date : 2025-08-27 DOI: 10.1016/j.gpeds.2025.100288
Pietro Ferrara , Margherita Zona , Ignazio Cammisa , Ida Giardino , Maria Pastore , Mehmet Vural , Massimo Pettoello-Mantovani , Francesca Scaltrito , Clara Pettoello-Mantovani
Witness Protection Programs are indispensable tools in the fight against organized crime, designed to safeguard individuals whose testimonies are crucial for justice. While these programs have demonstrated remarkable success in ensuring the physical safety of adult witnesses, the profound and often unaddressed challenges faced by accompanying children and adolescents represent a critical oversight. This article examines the multifaceted psychosocial, familial, educational, and societal hurdles encountered by children and adolescents relocated within western witness protection programs, focusing in particular on Europe and the US. Drawing upon existing literature, this report elucidates the cumulative trauma, identity disruption, social isolation, and educational instability inherent in their experiences. The analysis reveals a historical underestimation of children's unique vulnerabilities and rights within these programs. Recommendations emphasize the urgent need for a paradigm shift towards child-centric and family-focused western witness protection programs, advocating for holistic assessment, integrated mental health services, prioritized educational continuity, proactive social integration strategies, community engagement, enhanced professional training, and robust long-term research to ensure the comprehensive well-being of this exceptionally vulnerable population.
证人保护方案是打击有组织犯罪不可或缺的工具,旨在保护其证词对司法至关重要的个人。虽然这些项目在确保成年证人的人身安全方面取得了显著的成功,但陪伴在身边的儿童和青少年所面临的深刻且往往未得到解决的挑战是一个严重的疏忽。本文考察了在西方证人保护计划中安置的儿童和青少年所遇到的多方面的心理社会、家庭、教育和社会障碍,特别是在欧洲和美国。根据现有文献,本报告阐明了他们经历中固有的累积创伤、身份破坏、社会孤立和教育不稳定。该分析揭示了对这些项目中儿童独特的脆弱性和权利的历史低估。建议强调迫切需要将范式转变为以儿童为中心和以家庭为中心的西方证人保护计划,倡导全面评估,综合心理健康服务,优先考虑教育连续性,积极的社会融合战略,社区参与,加强专业培训,以及强有力的长期研究,以确保这一特别脆弱人群的全面福祉。
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引用次数: 0
The silent wounds of war: Psycho-physical impacts and international legal implications for children in conflict zones 战争无声的创伤:对冲突地区儿童的身心影响和国际法律影响
Pub Date : 2025-08-25 DOI: 10.1016/j.gpeds.2025.100287
Pietro Ferrara , Margherita Zona , Ida Giardino , Francesca Scaltrito , Clara Pettoello-Mantovani , Ignazio Cammisa
Children exposed to war confront a distinct array of adversities that extend far beyond the immediate threats of violence and displacement. While the direct consequences—such as physical harm, the loss of loved ones, and the destruction of homes—are profoundly distressing, the more insidious and enduring damage often stems from the disruption of critical developmental processes. Armed conflict undermines the foundational elements required for healthy childhood development, including emotional security, consistent caregiving, education, accessible healthcare, stable social networks, and physical safety. The psychological impact of living in, or fleeing from, conflict zones infiltrates all aspects of a child's life. The breakdown of community infrastructure, forced displacement, and prolonged uncertainty severely limit opportunities for peer interaction, structured play, and social learning—experiences that are vital for shaping self-concept, empathy, and emotional regulation. In environments where fear, mistrust, and violence become normalized, children may struggle to form secure attachments or to envision a hopeful future. It is widely recognized that environmental and contextual factors exert a profound influence on children's developmental trajectories, encompassing cognitive, emotional, and physical domains. Research consistently highlights the role of neighborhood safety, access to healthcare and education, and socioeconomic stability in shaping developmental outcomes. At the neurobiological level, chronic exposure to stress activates regulatory systems such as the hypothalamic–pituitary–adrenal (HPA) axis, which, when persistently engaged, can interfere with brain maturation. This dysregulation is often associated with impairments in memory, attention, language acquisition, and executive functioning, and with increased susceptibility to internalizing disorders such as post-traumatic stress disorder (PTSD), anxiety, depression, and attachment-related difficulties.
Physiologically, prolonged stress can weaken immune function, disturb sleep patterns, hinder somatic growth, and elevate the risk of both acute health problems and chronic diseases. The pervasive and multi-dimensional impact of war on children calls not only for academic inquiry but also for immediate ethical and policy responses. This article emphasizes that a nuanced understanding of trauma's effects across developmental systems is critical to inform targeted, trauma-responsive interventions.
The aim is to raise attention on the importance of establishing effective strategies, which must prioritize not only the treatment of individual symptoms but also broader efforts aimed at prevention and systemic recovery, thereby fostering resilience and contributing to the long-term rehabilitation of communities affected by conflict.
身处战争中的儿童面临着一系列独特的逆境,远远超出了暴力和流离失所的直接威胁。虽然直接后果——如身体伤害、失去亲人和家园被毁——令人深感痛苦,但更为隐蔽和持久的损害往往源于关键发育过程的中断。武装冲突破坏了儿童健康发展所需的基本要素,包括情感安全、持续照料、教育、可获得的医疗保健、稳定的社会网络和人身安全。生活在冲突地区或逃离冲突地区的心理影响渗透到儿童生活的各个方面。社区基础设施的崩溃、被迫流离失所和长期的不确定性严重限制了同伴互动、有组织的游戏和社会学习经验的机会,而这些对塑造自我概念、同理心和情绪调节至关重要。在恐惧、不信任和暴力变得常态化的环境中,儿童可能难以形成安全的依恋关系或设想一个充满希望的未来。人们普遍认为,环境和背景因素对儿童的发展轨迹产生深远的影响,包括认知、情感和身体领域。研究一贯强调社区安全、获得保健和教育的机会以及社会经济稳定在形成发展成果方面的作用。在神经生物学水平上,长期暴露于压力会激活调节系统,如下丘脑-垂体-肾上腺(HPA)轴,如果持续参与,会干扰大脑的成熟。这种失调通常与记忆、注意力、语言习得和执行功能的损伤有关,并与内化障碍(如创伤后应激障碍(PTSD)、焦虑、抑郁和依恋相关困难)的易感性增加有关。从生理上讲,长期的压力会削弱免疫功能,扰乱睡眠模式,阻碍身体发育,增加急性健康问题和慢性疾病的风险。战争对儿童的普遍和多方面影响不仅要求进行学术调查,而且要求立即作出道德和政策反应。这篇文章强调,对创伤在整个发育系统中的影响进行细致入微的理解,对于告知有针对性的、创伤反应性的干预措施至关重要。其目的是提高人们对制定有效战略的重要性的重视,这些战略不仅必须优先考虑治疗个别症状,而且必须优先考虑旨在预防和系统恢复的更广泛努力,从而增强复原力并促进受冲突影响社区的长期恢复。
{"title":"The silent wounds of war: Psycho-physical impacts and international legal implications for children in conflict zones","authors":"Pietro Ferrara ,&nbsp;Margherita Zona ,&nbsp;Ida Giardino ,&nbsp;Francesca Scaltrito ,&nbsp;Clara Pettoello-Mantovani ,&nbsp;Ignazio Cammisa","doi":"10.1016/j.gpeds.2025.100287","DOIUrl":"10.1016/j.gpeds.2025.100287","url":null,"abstract":"<div><div>Children exposed to war confront a distinct array of adversities that extend far beyond the immediate threats of violence and displacement. While the direct consequences—such as physical harm, the loss of loved ones, and the destruction of homes—are profoundly distressing, the more insidious and enduring damage often stems from the disruption of critical developmental processes. Armed conflict undermines the foundational elements required for healthy childhood development, including emotional security, consistent caregiving, education, accessible healthcare, stable social networks, and physical safety. The psychological impact of living in, or fleeing from, conflict zones infiltrates all aspects of a child's life. The breakdown of community infrastructure, forced displacement, and prolonged uncertainty severely limit opportunities for peer interaction, structured play, and social learning—experiences that are vital for shaping self-concept, empathy, and emotional regulation. In environments where fear, mistrust, and violence become normalized, children may struggle to form secure attachments or to envision a hopeful future. It is widely recognized that environmental and contextual factors exert a profound influence on children's developmental trajectories, encompassing cognitive, emotional, and physical domains. Research consistently highlights the role of neighborhood safety, access to healthcare and education, and socioeconomic stability in shaping developmental outcomes. At the neurobiological level, chronic exposure to stress activates regulatory systems such as the hypothalamic–pituitary–adrenal (HPA) axis, which, when persistently engaged, can interfere with brain maturation. This dysregulation is often associated with impairments in memory, attention, language acquisition, and executive functioning, and with increased susceptibility to internalizing disorders such as post-traumatic stress disorder (PTSD), anxiety, depression, and attachment-related difficulties.</div><div>Physiologically, prolonged stress can weaken immune function, disturb sleep patterns, hinder somatic growth, and elevate the risk of both acute health problems and chronic diseases. The pervasive and multi-dimensional impact of war on children calls not only for academic inquiry but also for immediate ethical and policy responses. This article emphasizes that a nuanced understanding of trauma's effects across developmental systems is critical to inform targeted, trauma-responsive interventions.</div><div>The aim is to raise attention on the importance of establishing effective strategies, which must prioritize not only the treatment of individual symptoms but also broader efforts aimed at prevention and systemic recovery, thereby fostering resilience and contributing to the long-term rehabilitation of communities affected by conflict.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100287"},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Montenegro Charter for the protection and recovery of children in disasters 保护和恢复灾难中儿童的黑山宪章
Pub Date : 2025-08-20 DOI: 10.1016/j.gpeds.2025.100286
Neboija Kavaric , Joseph Haddad , Massimo Pettoello-Mantovani
The Charter was jointly developed by EPA-UNEPSA and the International Pediatric Association (IPA) through the contributions of ideas and recommendations from presidents and delegates of European National Pediatric Societies who participated in the 2nd EPA-UNEPSA Hot Topics International Meeting held in Budva, Montenegro, on June 12, 2025 in collaboration with the Association for Preventive Pediatrics of Montenegro,: Giuseppe Buonocore, former President, Italian Academy of Pediatrics; Robert Cohen, President, Conseil National Professionnel de Pédiatrie, Association Française de Pédiatrie Ambulatoire; Pietro Ferrara vice-President, Italian Society of Pediatrics; Hilary Hoey, former President, Faculty of Paediatrics, Royal College Physicians Ireland; Esin Koc, President, Turkish Neonatal Society & the Union of European Neonatal and Perinatal Societies (UENPS); Georgios Konstantinidis, President, Serbian Pediatric Association; Georgina Kuli Lito, President, Albanian Society of Pediatrics; Hajrija Maksić, President, BIH Pediatric Association; Aida Mujkić, President, Pediatric Society of Croatia; Leyla Namazova, President UPR; Tudor Pop, President, Romanian Society of Preventive Pediatrics; Beiqi Ramus, President, Kosovo Pediatric Association; Aspazija Sofijanova, President, N.Macedonia Pediatric Association; Eli Somekh, former President, Israeli Pediatric Association; Tarana Taghi-zada, President, Azerbaijan Pediatric Association & Vice president, Eurasian Federation Children's Doctors; Stephen Turner, President, Royal College of Paediatrics and Child Health, UK; Mehmet Vural, former President, Turkish Pediatric Association. The International Pediatric Association (IPA) and EPA-UNEPSA gratefully acknowledge their invaluable contributions.
该宪章由EPA-UNEPSA和国际儿科协会(IPA)共同制定,通过参加2025年6月12日在黑山布德瓦举行的第二届EPA-UNEPSA热门话题国际会议的欧洲国家儿科学会主席和代表的想法和建议,与黑山预防儿科协会合作,其中包括:Giuseppe Buonocore,意大利儿科学会前主席;法国逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期逍遥期Pietro Ferrara意大利儿科学会副主席;Hilary Hoey,爱尔兰皇家医学院儿科学院前院长;Esin Koc,土耳其新生儿协会和欧洲新生儿和围产期协会联盟(unenps)主席;塞尔维亚儿科协会主席Georgios Konstantinidis;阿尔巴尼亚儿科学会主席Georgina Kuli Lito;波黑儿科协会主席Hajrija maksiki;克罗地亚儿科学会主席Aida mujkiki;普遍定期审议主席莱拉·纳马索娃;Tudor Pop,罗马尼亚预防儿科学会主席;科索沃儿科协会主席Beiqi Ramus;马其顿儿科协会主席Aspazija Sofijanova;Eli Somekh,以色列儿科协会前主席;Tarana Taghi-zada,阿塞拜疆儿科协会主席,欧亚儿童医生联合会副主席;Stephen Turner,英国皇家儿科和儿童健康学院院长;Mehmet Vural,土耳其儿科协会前主席。国际儿科协会(IPA)和环境保护署-联合国环境保护署感谢他们的宝贵贡献。
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引用次数: 0
International legal implications for children in conflict zones 对冲突地区儿童的国际法律影响
Pub Date : 2025-08-15 DOI: 10.1016/j.gpeds.2025.100285
Clara Pettoello-Mantovani , Margherita Zona , Francesca Scaltrito , Ignazio Cammisa , Ida Giardino , Pietro Ferrara
This article examines the unique vulnerability of children in armed conflict, emphasizing the interplay between their developmental stage, inherent dependency, and evolving legal status. It explores the international legal framework for child protection, which integrates International Humanitarian Law, International Human Rights Law, and International Criminal Law to mitigate the impacts of conflict and ensure accountability for violations. Despite the existence of robust legal instruments, a persistent gap remains between legal norms and their effective implementation, resulting in ongoing harm to children. The article highlights how international law not only prohibits acts such as killing, maiming, and attacks on schools and hospitals but also mandates obligations for recovery, reintegration, and access to health and education—implicitly addressing the psycho-physical harm children endure. Arguing that legal understanding must extend beyond legal professionals to include healthcare providers, the article calls for interdisciplinary collaboration to protect children more effectively. It concludes by advocating for the integration of Mental Health and Psychosocial Support (MHPSS) as an explicit and adequately resourced component of the right to health in humanitarian responses, to address the full spectrum of children's needs in conflict settings.
本文探讨了儿童在武装冲突中的独特脆弱性,强调了他们的发展阶段、内在依赖性和不断演变的法律地位之间的相互作用。它探讨了儿童保护的国际法律框架,该框架整合了国际人道主义法、国际人权法和国际刑法,以减轻冲突的影响并确保对侵权行为的问责。尽管存在强有力的法律文书,但法律规范与其有效执行之间仍然存在差距,导致对儿童的持续伤害。这篇文章强调,国际法不仅禁止杀害、致残和袭击学校和医院等行为,而且规定了康复、重返社会和获得保健和教育的义务——这隐含地解决了儿童遭受的身心伤害。这篇文章认为,法律理解必须从法律专业人员扩展到包括医疗保健提供者,它呼吁开展跨学科合作,以更有效地保护儿童。最后,它倡导将精神健康和社会心理支持作为人道主义应对中健康权的一个明确和资源充足的组成部分纳入其中,以解决冲突环境中儿童的各种需求。
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引用次数: 0
Analysis of the motor proficiency and physical capacity of asthmatic children and adolescents: A cross-sectional study 哮喘儿童和青少年运动熟练度和体能分析:一项横断面研究
Pub Date : 2025-08-14 DOI: 10.1016/j.gpeds.2025.100284
Josiane G Luiz , Évelim Leal de Freitas Dantas Gomes , Manoella Cavalcante de Andrade , Dirceu Costa

Background

Exercise restrictions due to asthma are associated with a sedentary lifestyle and reduced physical activity. Based on the limited data available in the literature, improvements in motor proficiency among individuals with respiratory diseases may be related to increased physical activity and better performance in activities of daily living. Therefore, the aim of this study was to evaluate motor proficiency and its association with aerobic capacity in children and adolescents with asthma.

Methods

A cross-sectional study was conducted. Motor proficiency was evaluated using the Movement Assessment Battery for Children – 2nd edition (MABC-2). Aerobic capacity was assessed using the Modified Shuttle Walk Test (MSWT). Asthma control was determined using the Asthma Control Questionnaire (ACQ6).

Results

Fifty participants not engaged in regular physical activity (25 with asthma and 25 controls) were evaluated. The mean age was 7.7 ± 2.65 years in the asthma group (AG) and 10.9 ± 3.89 years in the control group (CG). Both groups performed below predicted values in the MSWT (58.7 ± 21.3 % AG and 66.8 ± 29.2 % CG). The AG performed significantly worse than the CG on the aiming and catching subscale of the MABC-2 (15.4 ± 5.23 and 20.1 ± 7.06, p = 0.01, respectively). Moreover, a moderate negative correlation was found between manual dexterity and asthma control (r = -0.51, p = 0.02). Each 9.79-point increase in the MABC-2 manual dexterity subscale was associated with a 1.72-point reduction in the ACQ6.

Conclusions

Low aerobic capacity appears to negatively impact balance, and poor asthma control appears to negatively affect manual dexterity in the AG. Moreover, the AG had worse performance in aiming and catching compared to the CG.
背景:哮喘引起的运动限制与久坐不动的生活方式和体力活动减少有关。基于文献中有限的数据,呼吸系统疾病患者运动能力的提高可能与体力活动的增加和日常生活活动的改善有关。因此,本研究的目的是评估儿童和青少年哮喘患者的运动熟练程度及其与有氧能力的关系。方法采用横断面研究。运动能力评估使用儿童运动评估电池-第二版(MABC-2)。使用改良穿梭行走测试(MSWT)评估有氧能力。采用哮喘控制问卷(Asthma control Questionnaire, ACQ6)确定哮喘控制情况。结果对50名不从事常规体育活动的参与者(哮喘患者25名,对照组25名)进行了评估。哮喘组(AG)平均年龄7.7±2.65岁,对照组(CG)平均年龄10.9±3.89岁。两组的MSWT均低于预测值(58.7±21.3% AG和66.8±29.2% CG)。在MABC-2的瞄准和捕获分量表上,AG组的得分分别为15.4±5.23和20.1±7.06,p = 0.01,显著低于CG组。此外,手灵巧度与哮喘控制之间存在中度负相关(r = -0.51, p = 0.02)。MABC-2手灵巧子量表每增加9.79分,ACQ6就会减少1.72分。结论有氧能力缓慢会对平衡产生负面影响,哮喘控制不佳会对手灵巧性产生负面影响。此外,AG在瞄准和捕捉方面的表现也比CG差。
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引用次数: 0
The use of photography for qualitative data collection with adolescent mothers: a scoping review 使用摄影对青少年母亲的定性数据收集:范围审查
Pub Date : 2025-08-09 DOI: 10.1016/j.gpeds.2025.100283
Daniela de Castro Barbosa Leonello , Giovanna Ushirobira Souza , Rhyquelle Rhibna Neris , Giovanna Cristina Machado Kayzuka , Marina Prado de Souza , Adriana Moraes Leite

Introduction

Photography has been increasingly explored in data collection processes, as it enriches the process and allows the interviewee to take on the role of protagonist [1]. Among the methods that use images, Photovoice and Photo-Elicitation stand out in qualitative research [2]. The objective of this research was to map the development of Photo-Elicitation and Photovoice methods with adolescent mothers as data collection techniques.

Methods

A scoping review was conducted from August to October 2024. The guiding question formulated was: "How have Photo-Elicitation and Photovoice been developed with adolescent mothers as a data collection method?". The search strategy included LILACS, PubMed, CINAHL, and Web of Science.

Results

A total of 46 articles were found, mostly published in English. Ten were selected after full-text reading.

Conclusion

The literature converges in considering Photo-Elicitation and Photovoice as visual and interactive resources that facilitate the communication of adolescent mothers' experiences.
在数据收集过程中越来越多地探索摄影,因为它丰富了过程,让受访者扮演主角[1]的角色。在使用图像的方法中,Photovoice和Photo-Elicitation在定性研究中脱颖而出。本研究的目的是绘制以青少年母亲为数据收集技术的photoelicitation和Photovoice方法的发展图。方法于2024年8月至10月进行范围综述。提出的指导性问题是:“photoelicitation和Photovoice是如何与青少年母亲一起发展成为一种数据收集方法的?”搜索策略包括LILACS、PubMed、CINAHL和Web of Science。结果共收录文献46篇,以英文发表为主。全文阅读后选出10个。结论文献一致认为photoelicitation和Photovoice是促进青春期母亲经验交流的视觉和互动资源。
{"title":"The use of photography for qualitative data collection with adolescent mothers: a scoping review","authors":"Daniela de Castro Barbosa Leonello ,&nbsp;Giovanna Ushirobira Souza ,&nbsp;Rhyquelle Rhibna Neris ,&nbsp;Giovanna Cristina Machado Kayzuka ,&nbsp;Marina Prado de Souza ,&nbsp;Adriana Moraes Leite","doi":"10.1016/j.gpeds.2025.100283","DOIUrl":"10.1016/j.gpeds.2025.100283","url":null,"abstract":"<div><h3>Introduction</h3><div>Photography has been increasingly explored in data collection processes, as it enriches the process and allows the interviewee to take on the role of protagonist [1]. Among the methods that use images, <em>Photovoice</em> and Photo-Elicitation stand out in qualitative research [2]. The objective of this research was to map the development of Photo-Elicitation and <em>Photovoice</em> methods with adolescent mothers as data collection techniques.</div></div><div><h3>Methods</h3><div>A scoping review was conducted from August to October 2024. The guiding question formulated was: \"How have Photo-Elicitation and <em>Photovoice</em> been developed with adolescent mothers as a data collection method?\". The search strategy included LILACS, PubMed, CINAHL, and <em>Web of Science</em>.</div></div><div><h3>Results</h3><div>A total of 46 articles were found, mostly published in English. Ten were selected after full-text reading.</div></div><div><h3>Conclusion</h3><div>The literature converges in considering Photo-Elicitation and <em>Photovoice</em> as visual and interactive resources that facilitate the communication of adolescent mothers' experiences.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100283"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food and housing insecurity, adverse childhood experiences, and pediatric emergency department use 食物和住房不安全,不良的童年经历,和儿科急诊科使用
Pub Date : 2025-08-06 DOI: 10.1016/j.gpeds.2025.100282
Raymen R. Assaf , Theodore Heyming , Tricia Morphew , Kellie Bacon , Shelby Shelton , Jason A. Douglas

Objective

To describe the relationship between neighborhood-level repression-adverse childhood experiences (ACEs) (family member incarceration, community violence, discrimination), food and housing insecurity, and pediatric emergency department (ED) utilization.

Methods

The measured exposures were food/housing insecurity, repression-ACEs, and childhood opportunity index (COI 3.0) based on caregiver/patient surveys and home address. The primary outcome was ED visits 12 months before and after the ED index visit. Multivariable regression models examined associations between the exposures and annual ED visit rates per 100 patients, adjusting for potential confounders.

Results

From March 2021 - May 2023 6228 patients (range 0–22 years) had an index ED visit. 64.9 % were Hispanic, 7.0 % Asian, 1.9 % Black, 7.0 % Other/multiple races, and 19.1 % White. Of the participants, 11.6 % had a repression-ACE; 22.3 % food or housing insecurity, and average COI was moderate (53.3, SD = 23.8). Food and housing insecurity were higher among Black (29.0 %) and Hispanic (26.3 %) participants (p < 0.001). Very low to moderate COI was highest in Black (51.3 %) and Hispanic (77.4 %) participants (p < 0.001). Black participants reported the highest repression-ACEs (25.6 %, p < 0.001). In univariate analyses, food insecurity (RR = 1.12, p = 0.07) and housing insecurity (RR = 1.13, p = 0.04) increased the ED visit rate. Experiencing discrimination increased this rate by 27 %, (RR = 1.27, p = 0.02). The effect of violence exposure (p = 0.03) and family member incarceration (p = 0.07) on ED visit rate varied across racial groups.

Conclusions

Repression-ACEs interact with race and ethnicity and social inequities (food/housing insecurity, COI) in shaping ED utilization. Impacts of ACEs on children’s health continue to shape inequities in pediatrics while defining areas for action.
目的探讨社区压抑不良童年经历(ace)(家庭成员监禁、社区暴力、歧视)、食物和住房不安全感与儿科急诊科(ED)使用率之间的关系。方法根据照顾者/患者调查和家庭住址,测量食物/住房不安全感、压抑- ace和童年机会指数(COI 3.0)。主要结局是ED指数访视前后12个月的ED访视。多变量回归模型检验了暴露与每100名患者每年ED就诊率之间的关系,并对潜在的混杂因素进行了调整。结果从2021年3月至2023年5月,6228例患者(年龄0-22岁)进行了指数ED就诊。64.9%为西班牙裔,7.0%为亚洲人,1.9%为黑人,7.0%为其他/多种族,19.1%为白人。在参与者中,11.6%患有抑制性ace;22.3%为食物或住房不安全,平均COI为中等(53.3,SD = 23.8)。黑人(29.0%)和西班牙裔(26.3%)参与者的食物和住房不安全感更高(p <;0.001)。极低至中度COI在黑人(51.3%)和西班牙裔(77.4%)参与者中最高(p <;0.001)。黑人参与者报告了最高的压抑- ace (25.6%, p <;0.001)。在单变量分析中,食品不安全(RR = 1.12, p = 0.07)和住房不安全(RR = 1.13, p = 0.04)增加了急诊科就诊率。遭受歧视使这一比率增加了27% (RR = 1.27, p = 0.02)。暴力暴露(p = 0.03)和家庭成员监禁(p = 0.07)对急诊科就诊率的影响在不同种族之间存在差异。结论压抑性ace与种族、民族和社会不平等(食物/住房不安全,COI)相互作用,影响ED的利用。ace对儿童健康的影响在确定行动领域的同时,继续形成儿科的不平等现象。
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引用次数: 0
Neonatal umbilical hernia: A simple noninvasive technique 新生儿脐疝:一种简单的无创技术
Pub Date : 2025-08-06 DOI: 10.1016/j.gpeds.2025.100280
Jayalaxmi Shripati Aihole

Background

A congenital umbilical hernia is a common anomaly seen at birth or during infancy, as a small or large umbilical bulge or swelling due to herniation of the bowel or omentum, mostly requiring medical attention. If umbilical fascial ring fails to close and obliterate after the separation of umbilical cord soon after birth, will be clinically presenting as umbilical hernia. Though spontaneous resolution of umbilical hernia is established fact, but however, duration of it, is still a matter of speculation and what should be done during this waiting period: twiddling the thumbs? and how to avoid surgical interventions or morbidities.

Aim and methods

Hence author proposes here a conservative, non-invasive management technique by mother herself to help to heal her baby from this anomaly during this watchful expectancy period to avoid fatalities.
背景先天性脐疝是出生或婴儿期常见的异常,表现为肠或网膜疝引起的或大或小的脐隆起或肿胀,大多需要就医。如果出生后不久脐带分离后,脐带筋膜环未能闭合闭塞,则临床表现为脐疝。虽然脐疝的自然消退是既定事实,但是,它的持续时间,仍然是一个猜测的问题,在这段等待期间应该做些什么:玩弄拇指?以及如何避免手术干预或并发症。目的和方法作者在此提出了一种保守的、非侵入性的管理技术,以帮助母亲在这一观察预期期间治愈婴儿的异常,以避免死亡。
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引用次数: 0
期刊
Global pediatrics
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