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A case of primary vasoproliferative tumor with full-thickness macular hole 原发性血管增生性肿瘤伴全层黄斑孔1例
Pub Date : 2022-02-08 DOI: 10.3205/oc000189
P. Rishi, Janani Sreenivasan
A 53-year-old female presented with defective vision in the left eye of one week duration with a best-corrected visual acuity (BCVA) of 6/9. Fundus examination showed a primary retinal vasoproliferative tumor (RVPT) at the inferotemporal quadrant and a small full-thickness macular hole (MH). The patient underwent cryotherapy for RVPT, followed later by vitrectomy with internal limiting membrane peeling and gas tamponade. The tumor regressed and the MH was closed with BCVA of 6/9. RVPT can present with remote macular complications like epiretinal membrane, cystoid macular edema, macular exudates, and rarely full-thickness MH. Management should be directed towards the tumor as well as the complication.
患者为53岁女性,左眼视力缺损1周,最佳矫正视力(BCVA) 6/9。眼底检查显示颞下象限原发性视网膜血管增殖性肿瘤(RVPT)和一个小的全层黄斑孔(MH)。患者接受RVPT冷冻治疗,随后进行玻璃体切除术,内限制膜剥离和气体填塞。肿瘤消退,闭合MH, BCVA为6/9。RVPT可出现远端黄斑并发症,如视网膜前膜、囊样黄斑水肿、黄斑渗出,很少出现全层MH。治疗应针对肿瘤及并发症。
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引用次数: 0
Melkersson-Rosenthal syndrome: a rare variant of the monosymptomatic form Melkersson Rosenthal综合征:一种罕见的单症状形式的变体
Pub Date : 2022-02-08 DOI: 10.3205/oc000191
C. Estacia, A. G. Gameiro Filho, Izadora Bouzeid Estacia da Silveira, Rodrigo Rosa Gameiro, Anna Laura Salabert Della Barba
Melkersson-Rosenthal syndrome (MRS) is a rare condition without any known etiology. It is characterized by the triad facial paralysis, facial swelling, and the development of folds and furrows at the tongue (fissured tongue). This study aims to report a case of a 59-year-old patient complaining about asymmetric eyelid swelling that had started two years before, associated with pain and redness on her right eye, without repercussions on her visual acuity. The patient underwent a skin biopsy of the right eye’s lower eyelid, which was compatible with the monosymptomatic form of MRS. Consequently, five injections of triamcinolone were performed for the period of one year, with gradual and satisfactory improvement. One year after the end of the treatment, the patient returned with recurrence of the swelling, and therapy with triamcinolone associated with oral steroids was started. However, due to the lack of improvement, Tacrolimus ointment 0.03% was initiated. The patient evolved with an important and significant reduction of the eyelid edema, still being followed at the Hospital Federal dos Servidores do Estado do Rio de Janeiro.
梅尔克松-罗森塔尔综合征(MRS)是一种罕见的疾病,没有任何已知的病因。其特征是三合性面瘫、面部肿胀以及舌部褶皱和犁沟的发育(裂舌)。这项研究旨在报告一例59岁的患者,她抱怨两年前开始的不对称眼睑肿胀,并伴有右眼疼痛和发红,但对视力没有影响。患者接受了右眼下眼睑的皮肤活检,这与MRS的单症状形式一致。因此,在一年的时间里,进行了五次曲安奈德注射,病情逐渐好转,令人满意。治疗结束一年后,患者再次出现肿胀,开始使用曲安奈德联合口服类固醇进行治疗。然而,由于缺乏改善,开始使用0.03%的他克莫司软膏。患者的眼睑水肿得到了重要而显著的减轻,仍在里约热内卢联邦医院接受随访。
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引用次数: 1
Lose the Nintendo and thou shall be healed! Restoring vision in malingering 丢掉任天堂,你就会痊愈!在装病中恢复视力
Pub Date : 2022-02-08 DOI: 10.3205/oc000192
Michel van Lint, Dave Kloeck, E. V. van Aken
Non-organic visual loss can be hard to prove or explain to the parents of affected children at times. Here, we describe a simple yet effective approach that may help solve both issues by ensuring that the patient refrains from visual stimuli.
非器质性视力丧失有时很难证明或向受影响儿童的父母解释。在这里,我们描述了一个简单而有效的方法,可以帮助解决这两个问题,确保患者避免视觉刺激。
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引用次数: 0
A case of anterior scleritis in association with posterior scleritis – a diagnostic riddle 前巩膜炎合并后巩膜炎1例-一个诊断难题
Pub Date : 2022-02-08 DOI: 10.3205/oc000188
Aditi G Dastidar, Sugandha Goel, D. Kundu, J. Biswas, E. Nigam, Preeti Sharma
We herein report a case of a young female presenting with multiple nodular scleral abscesses mimicking infective scleritis with exudative retinal detachment. Repeated diagnostic scraping for microbiological and histopathological analysis was inconclusive. The patient’s systemic and collagen disease work-up was non-contributory. She was treated with multiple surgical debridement and de-roofing of the abscesses along with antibiotic irrigation. Topical and oral steroid was stopped on worsening of the condition, and the patient was maintained on topical and oral antibiotics. Complete resolution of scleritis and exudative detachment was noted at 1 month follow-up and no recurrence was noted until 6 months.
我们在此报告一个年轻女性的情况下,表现为多发性结节性巩膜脓肿模拟感染性巩膜炎和渗出性视网膜脱离。反复刮痧进行微生物学和组织病理学分析尚无定论。患者的全身和胶原蛋白疾病检查无贡献。她接受了多次手术清创和去顶脓肿以及抗生素冲洗。病情恶化时停用局部和口服类固醇,患者继续使用局部和口服抗生素。随访1个月,巩膜炎和渗出性脱离完全消失,6个月无复发。
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引用次数: 0
Intravitreal melphalan for persistent retinoblastoma vitreous seeds 玻璃体内melphalan治疗持续性视网膜母细胞瘤
Pub Date : 2022-02-08 DOI: 10.3205/oc000190
Marie Jeazelle H. Redondo-Villanueva, G. V. Mercado
A 7-month-old male presented with bilateral retinoblastoma, initially group E OD and group C OS (International Intraocular Retinoblastoma Classification). The patient underwent enucleation with adjuvant chemotherapy and radiotherapy on the right eye for extraocular retinoblastoma. The main tumors on the left eye regressed with combined neoadjuvant chemotherapy with focal therapy, but had persistent sphere vitreous seeds overlying the tumor at the superotemporal mid-periphery and at the inferior periphery. Intravitreal injection of melphalan was performed. Vitreous seeds were clinically undetectable after 2 cycles of injection. Six months from the 2nd intravitreal injection of melphalan, there was no evidence of new tumors nor vitreous seeds in the left eye. No documented complications of intravitreal melphalan injection were experienced. This is the first documented successful treatment of vitreous seeds with intravitreal melphalan at the Ocular Oncology/Retinoblastoma Unit of the University of the Philippines, Philippine General Hospital.
一例7个月大的男性双侧视网膜母细胞瘤,最初为E组OD和C组OS(国际眼内视网膜母细胞瘤分类)。患者因眼外视网膜母细胞瘤行右眼去核及辅助化疗和放疗。经新辅助化疗联合局灶治疗,左眼主要肿瘤消退,但颞上中外周和下外周有持续的球状玻璃体种子覆盖肿瘤。玻璃体内注射美法兰。注射2个周期后,临床未检出玻璃体种子。第2次玻璃体内注射melphalan 6个月后,左眼未见新的肿瘤和玻璃体种子。未见玻璃体腔内注射美法兰的并发症。这是菲律宾综合医院菲律宾大学眼科肿瘤学/视网膜母细胞瘤科首次记录成功的玻璃体种子玻璃体内melphalan治疗。
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引用次数: 1
Visual complaints in pregnancy: (pre)eclampsia as a chameleon. 孕期视觉主诉:(先兆)子痫像变色龙。
Pub Date : 2022-01-01 DOI: 10.3205/oc000208
Johanna Wiedemann, Lebriz Altay, Antje Neugebauer, Tim Krohne, Claus Cursiefen
Objective: The visual system often is affected in patients with preeclampsia and even more in cases of eclampsia, a life-threatening pregnancy complication. Symptoms include blurred vision and deterioration of visual acuity. Pregnancy can also affect pre-existing conditions, such as diabetic retinopathy. In this case series, we describe three patients with the same underlying condition, i.e. (pre)eclampsia who experienced acute visual disturbance whereas the final diagnosis was different: disseminated intravascular coagulopathy (DIC), posterior reversible encephalopathy syndrome (PRES), and diabetic retinopathy. Methods and results: All patients underwent a thorough slit lamp examination and ocular coherence tomography (OCT). All patients presented with acute impaired vision and subretinal fluid and-/or fibrin. Conclusions: These cases highlight the importance of early involvement of ophthalmologists when pregnant women complain about visual disorders.
目的:子痫前期患者的视觉系统经常受到影响,子痫是一种危及生命的妊娠并发症。症状包括视力模糊和视力下降。怀孕也会影响已有的疾病,比如糖尿病视网膜病变。在本病例系列中,我们描述了三例具有相同基础疾病的患者,即(前期)子痫,经历急性视觉障碍,但最终诊断不同:弥散性血管内凝血病(DIC),后可逆脑病综合征(PRES)和糖尿病视网膜病变。方法和结果:所有患者均行裂隙灯检查和眼相干断层扫描(OCT)。所有患者均表现为急性视力受损、视网膜下积液和-/或纤维蛋白。结论:这些病例强调了当孕妇抱怨视力障碍时,眼科医生早期介入的重要性。
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引用次数: 0
Hemi-central retinal artery occlusion following methanol toxicity. 甲醇中毒后半中央视网膜动脉闭塞。
Pub Date : 2022-01-01 DOI: 10.3205/oc000207
Mohammad Zarei, Sima Sheikhghomi, Masoud Aghsaei Fard

Objective: To describe a patient with hemi-retinal artery occlusion following methanol toxicity.

Methods: Observational case report.

Results: We report a case presented with an acute altitudinal visual field loss in the right eye following consumption of illicit alcoholic drink. In fundus photography, a well demarcated superior hemi-retinal whitening with foveal sparing was noted. Careful inspection of the optic nerve head in the right eye revealed that there was no main trunk of the central retinal artery anterior to the lamina cribrosa. Two separately emerging superior and inferior arterial trunks were noted. In fundus fluorescein angiography, earlier dye filling in the territory of the superior arterial trunk compared to the inferior arterial trunk was evident.

Conclusion: Hemi-central retinal occlusion may happen as an ocular consequence of methanol toxicity in patients with a proximal bifurcation of the central retinal artery.

目的:报告一例甲醇中毒致半视网膜动脉闭塞的病例。方法:观察性病例报告。结果:我们报告一个病例提出了一个急性高度视野丧失在右眼后,非法饮酒。眼底摄影显示,上半视网膜明显白化,中央凹保留。仔细检查右眼视神经头,发现视网膜中央动脉在筛板前没有主干。注意到两个单独出现的上、下动脉干。眼底荧光素血管造影显示,上动脉主干的染色明显早于下动脉主干。结论:在视网膜中央动脉近端分叉的患者中,甲醇中毒可能导致半中枢性视网膜闭塞。
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引用次数: 0
Active removal of anterior segment-migrated dexamethasone implant (Ozurdex®) 主动移除前段移位地塞米松植入物(Ozurdex®)
Pub Date : 2021-12-28 DOI: 10.3205/oc000195
Jozef Adelson M. Depla, M. Veckeneer, I. Bleyen
Background: Ozurdex® (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills.
背景:Ozurdex®(Allergan plc,都柏林,爱尔兰)是一种玻璃体内缓释地塞米松(DEX)植入物。据报道,植入物会迁移到前房,可能导致角膜失代偿。建议在玻璃体腔内及时取出或重新定位,但由于其脆弱性,这很麻烦。有几种技术存在,但所需的精心设置和专业手术技能可能会导致治疗延迟。我们报告了一种避免这些缺点的新颖技术。病例介绍:一名59岁的女性因前房移位的DEX植入物和角膜水肿导致视力下降,被送往急诊科。使用眼科粘性外科器械(OVD)和弯曲的19号针头,在局部麻醉下,在一分钟的手术中迅速取出植入物。结论:使用19号弯针抽吸前房移位DEX植入物是一种成本效益高、时间有效且安全的技术,不需要专业的手术技能。
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引用次数: 1
Unilateral simultaneous optic nerve and choroidal infiltration - unusual presentation of metastatic disease in breast carcinoma. 单侧视神经和脉络膜同时浸润——乳腺癌转移性疾病的不寻常表现。
Pub Date : 2021-09-21 eCollection Date: 2021-01-01 DOI: 10.3205/oc000187
Poninder Kumar, Ashok Kumar, Srujana Dubakka, Jaya Kaushik, Mohini Agrawal

Breast carcinoma metastasis can involve any ocular structures, but involvement of the optic nerve is extremely rare. Choroidal metastasis is usually multifocal as well as bilateral and occurs late. We report an unusual initial presentation of metastasis from breast cancer; unilateral infiltrative optic neuropathy with concurrent choroid metastatic deposits in an adequately treated middle-aged female. Our present case, wherein for the first time in the literature, we illustrated unilateral infiltrative optic neuropathy and choroidal metastatic deposits secondary to breast carcinoma, will increase our knowledge about the various potential ocular presentations of this relatively common malignant disease.

乳腺癌转移可累及任何眼部结构,但累及视神经极为罕见。脉络膜转移通常是多灶性和双侧的,发生较晚。我们报告一个不寻常的最初表现转移从乳腺癌;单侧浸润性视神经病变并发脉络膜转移沉积一例治疗充分的中年女性。本病例是文献中首次报道单侧浸润性视神经病变和继发于乳腺癌的脉络膜转移沉积,这将增加我们对这种相对常见的恶性疾病的各种潜在眼部表现的认识。
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引用次数: 1
Ocular trauma or Oedipism: completing the evisceration. 眼外伤或恋母癖:完成内脏取出。
Pub Date : 2021-08-04 eCollection Date: 2021-01-01 DOI: 10.3205/oc000186
Ujjwala Narang, Laura Maubon, Vishal Shah, Vijay Wagh

Self-enucleation, also known as Oedipism, is a rare form of ocular trauma. The objective of this clinical case report is to highlight the importance of diagnosing this unusual injury and thus ensuring its appropriate management. We herein describe a case of a 58-year-old man who presented to hospital with a bleeding left eye. Initially, limited history was provided, however, on further enquiry it was revealed that he had paranoid schizophrenia. The patient eventually had to be sectioned with assistance from the Police and Psychiatry team, upon discovery of self-inflicted mechanism of injury. Subsequently, the patient had evisceration of the left eye and afterwards, demonstrated insight into the pre-operative problems. Literature review emphasizes the importance of close cooperation required between medical specialities to ensure that the underlying cause, usually schizophrenia, is managed in conjunction to the eye injury in order to provide optimum care for the patient.

自我摘除,也被称为俄狄浦斯症,是一种罕见的眼部创伤。本临床病例报告的目的是强调诊断这种不寻常的损伤的重要性,从而确保其适当的管理。我们在此描述一个58岁的男子谁提出了医院左眼出血的情况。最初,提供了有限的病史,然而,进一步调查显示,他患有偏执型精神分裂症。最终,在警方及精神科小组的协助下,该名病人在发现其自残机制后,必须被分隔。随后,患者进行了左眼内脏切除,之后,对术前问题有了深入的了解。文献综述强调了医学专业之间密切合作的重要性,以确保潜在原因(通常是精神分裂症)与眼部损伤相结合,以便为患者提供最佳护理。
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引用次数: 0
期刊
GMS ophthalmology cases
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