Since the discovery of interleukin 8 (IL-8), about 50 chemokines have been characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines have been identified that are expressed constitutively and function in the physiological traffic and homing of leukocytes.
Martin Herrmann and colleagues briefly discuss how autoimmunity might be initiated and maintained in the systemic autoimmune disease systemic lupus erythematosus.
A recent conference* brought together scientists from 18 countries to discuss advances in our understanding of development, target-cell recognition, signal transduction, and effector mechanisms of natural killer (NK) cells.
Andrzej Mackiewicz, President of the 14th European Immunology Meeting, traces the history behind EFIS 2000, and describes the program of this most recent gathering of immunologists.
Recent data on the role of cytokines, chemokines and/or chemokine receptors associated with T helper 1 (Th1) and Th2 cells have highlighted their role in T lymphopoiesis, proliferative glomerulonephritis, angiogenesis, infection, pregnancy and unexplained recurrent abortions, and atopy.
Characteristics such as versatility, stability and high-level expression make adenovirus vectors invaluable tools for the expression of transgenes in mammalian cells for the development of recombinant viral vaccines and for delivery of therapeutic genes.
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：