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Assessment of patients with psoriasis undergoing treatment with narrowband UVB phototherapy in the State University of Pará, Brazil 巴西帕尔<e:1>州立大学窄带UVB光疗治疗银屑病患者的评估
Pub Date : 2018-03-29 DOI: 10.3823/2566
Michelle Fonseca Goiabeira, Débora Bacellar Cruz Nunes, Adriana Kamilly Leitão Pitman Machado, Samira Oliveira Silveira, Érica Baptista Pinto, Yandra Sherring Einecke, Juliana Bacellar Cruz Nunes, M. Nunes, Miguel Saraty de Oliveira, W. Loureiro, G. Amin, Maria Amélia Lopes dos Santos, A. Mendes, F. Carneiro
Introduction: Moderate and severe forms of psoriasis require phototherapy and/or systemic medications. The UVB band, with wavelength between 311 and 312nm, is called narrowband UVB (NB-UVB) and it has proven to be more beneficial for the psoriasis treatment. Goals: to characterize the group of patients with psoriasis treated with NB-UVB phototherapy, according to the clinical form, sex, phototype, and clinical evolution. Methods: All patients with psoriasis who underwent NB-UVB phototherapy between August 2016 and April 2017 were included in this study. Data on the patients were collected retrospectively. Results: During the study, 19 patients were treated with NB-UVB phototherapy, being 09 women (47%) and 10 men (53%), ages ranging from 22 to 81years. The most prevalent phototypes were III (42%) and IV (37%). Only 04 patients (21%) had guttate psoriasis and 15 (79%) had psoriasis vulgaris with variable severity. The total number of phototherapy sections, during the period evaluated, varied from 7 to 51, with an average of 25 sessions. It was observed that, 09 patients (47%) had a response beginning with up to two months of treatment. The minimum number of sections to start improvement varied from 8 to 28, with an average of 16 sessions. Conclusions: The use of NB-UVB phototherapy proved to be a safe and effective treatment, and should be considered a good therapeutic option for psoriasis.
中度和重度牛皮癣需要光疗和/或全身药物治疗。波长在311 - 312nm之间的UVB波段被称为窄带UVB (NB-UVB),它已被证明对牛皮癣的治疗更有益。目的:根据临床表现、性别、光型及临床演变,对NB-UVB光疗治疗的银屑病患者群体进行特征分析。方法:纳入2016年8月至2017年4月期间接受NB-UVB光疗的银屑病患者。回顾性收集患者资料。结果:19例患者接受了NB-UVB光疗,其中女性09例(47%),男性10例(53%),年龄22 ~ 81岁。最常见的照片类型是III型(42%)和IV型(37%)。只有04例(21%)有点滴型牛皮癣,15例(79%)有不同严重程度的寻常型牛皮癣。在评估期间,光疗的总次数从7次到51次不等,平均为25次。观察到,09名患者(47%)在长达两个月的治疗开始时出现反应。开始改进的最小节数从8到28不等,平均为16节。结论:NB-UVB光疗是一种安全有效的治疗银屑病的方法,是治疗银屑病的良好选择。
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引用次数: 1
Comparison of Dosage Requirement of Erythropoietin Stimulating Agent (ESA) in Maintenance of Hemoglobin Concentration in patients undergoing twice weekly versus thrice weekly Hemodialysis in Pakistani Population 在巴基斯坦人群中,每周2次与每周3次血液透析患者维持血红蛋白浓度时,促红细胞生成素刺激剂(ESA)用量需求的比较
Pub Date : 2018-03-25 DOI: 10.3823/2565
Osama Kunwer Naveed, M. Zafar, S. Mahmood, K. Mukhtar
Anemia is one of the major complications of patients with chronic kidney disease (CKD) undergoing hemodialysis (HD) and is associated with left ventricular hypertrophy and also increases morbidity and mortality. Anemia in patients with CKD can be due to two major reasons; iron deficiency or erythropoietin insufficiency. Erythropoietin Stimulating Agent (ESAs) administration is the mainstay in treating anemia if the patient is iron sufficient. However, higher doses of ESAs have been associated with increased cerebrovascular and cardiovascular events. We conducted this study to see how much erythropoietin is required in our setting in iron sufficient patients to maintain hemoglobin(Hb)  level and the effect of dialysis frequency on ESA doses.  Methods and Findings: A cross-sectional study was conducted at the Department of Nephrology at Ziauddin University Hospital. Patients’ charts were reviewed for Hb levels and doses of ESA to maintain Hb between 10-12 mg/dl. Patients were excluded if they had iron deficiency, malignancy, were on immunosuppressive agents, had renal transplant, and with Hb >12 mg/dl or <10 mg/dl and their ferritin levels, transferrin saturation, hemoglobin concentration, frequency of hemodialysis and ESA dosage were monitored. We also compared these variables between patients undergoing hemodialysis thrice weekly with those undergoing hemodialysis twice a week. A total of 105 patients were analyzed. 24 were excluded as they did not match the inclusion criteria. 81 patients were included in the study. 36 (44.4%) were males and 45 (55.6%) were females. Mean age of the patient was 56.47 ± 11.72 years. The average dose of ESA was 106.91 ± 61.47 for patients undergoing hemodialysis thrice weekly and 183.94 ± 116.71 for patients undergoing hemodialysis twice a week. Significant difference was found to exist between dosage of patients undergoing thrice weekly dialysis versus twice weekly dialysis(p=<0.001).  Our study has limitations. First our study only looked at Hb levels, iron stores and dosages of ESA, while other factors like Parathyroid Hormone(PTH) levels and Vitamin B12 were not considered that may have a role in anemia of chronic renal disease. In addition, it was a study limited to one center only and a multicenter trial should be taken to validate the results. We have reported one aspect of dialysis vintage i.e.  high ESA dosage requirement Conclusion: We found that patients undergoing hemodialysis three times a week require recommended dosage of ESA; however those undergoing hemodialysis less than three times a week require higher dosage of ESA to maintain Hb level. Here we report significant effect of hemodialysis on ESA dosage to maintain same level of Hb.
贫血是接受血液透析(HD)的慢性肾脏病(CKD)患者的主要并发症之一,与左心室肥大有关,还会增加发病率和死亡率。CKD患者的贫血可能由两个主要原因引起;铁缺乏或红细胞生成素缺乏。如果患者铁充足,则使用促红细胞生成素刺激剂(ESA)是治疗贫血的主要药物。然而,较高剂量的ESA与脑血管和心血管事件的增加有关。我们进行了这项研究,以了解在铁充足的患者中需要多少红细胞生成素来维持血红蛋白(Hb)水平,以及透析频率对ESA剂量的影响。方法和发现:在齐奥丁大学医院肾内科进行了一项横断面研究。对患者的图表进行了Hb水平和ESA剂量的审查,以将Hb维持在10-12mg/dl之间。如果患者患有缺铁、恶性肿瘤、服用免疫抑制剂、肾移植、Hb>12mg/dl或<10mg/dl,则将其排除在外,并监测其铁蛋白水平、转铁蛋白饱和度、血红蛋白浓度、血液透析频率和ESA剂量。我们还比较了每周三次血液透析患者和每周两次血液透析的患者之间的这些变量。共对105名患者进行了分析。24人因不符合入选标准而被排除在外。81名患者被纳入研究。男性36例(44.4%),女性45例(55.6%)。患者的平均年龄为56.47±11.72岁。每周三次血液透析患者的ESA平均剂量为106.91±61.47,每周两次血液透析的患者的ESA的平均剂量为183.94±116.71。每周透析三次的患者与每周透析两次的患者的剂量存在显著差异(p=0.001)。我们的研究有局限性。首先,我们的研究只关注Hb水平、铁储存量和ESA剂量,而其他因素,如甲状旁腺激素(PTH)水平和维生素B12,没有被考虑可能与慢性肾脏疾病贫血有关。此外,这是一项仅限于一个中心的研究,应进行多中心试验来验证结果。我们报道了透析年份的一个方面,即高ESA剂量需求。结论:我们发现每周进行三次血液透析的患者需要推荐剂量的ESA;然而,那些每周接受血液透析少于三次的患者需要更高剂量的ESA来维持Hb水平。在这里,我们报告了血液透析对ESA剂量的显著影响,以保持相同的Hb水平。
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引用次数: 0
Haemorrhage of gross domestic product from disability-adjusted-life-years among 15-59 year olds in Kenya 肯尼亚15-59岁人群残疾调整生命年造成的国内生产总值损失
Pub Date : 2018-03-24 DOI: 10.3823/2561
J. Kirigia, G. Mwabu
Background: This article estimates non-health gross domestic product (GDP) losses associated with Disability-Adjusted Life Years (DALY) lost among 15-59 year olds (most productive age bracket) in Kenya in 2015. Methods: This study employs the lost output or human capital approach (HCA) to convert the DALYs lost from all causes into their monetary equivalents. The magnitude economic haemorrhage from each disease was obtained by multiplying the per capita non-health GDP in International Dollars by the total number of DALYs lost in a specific age group (15-29 years, 30-49 years, 50-59 years). Per capita non-health GDP equals per capita GDP minus total health expenditure in 2015. Data on DALYs and per capita total health expenditure were obtained from the World Health Organization and per capita GDP data was from IMF databases. Results: Kenya lost 9,405,184 DALYs among 15-59 years olds in 2015. That DALY loss caused a haemorrhage in GDP of Int$ 29,788,392,419. Approximately 48.6% of the GDP haemorrhage resulted from communicable diseases and nutritional conditions, 37.4% from non-communicable diseases, and 14.0% from injuries. Conclusion: There is need to augment domestic and external investments into national health systems and other systems that meet basic needs (education, food, water, sanitation, shelter) to reduce disease burden. Key words: Non-health GDP, economic haemorrhage, disability-adjusted life year (DALY)
背景:本文估计了2015年肯尼亚15-59岁(生产能力最强的年龄段)人群中与残疾调整生命年(DALY)损失相关的非健康国内生产总值(GDP)损失。方法:本研究采用产出损失或人力资本法(HCA)将各种原因造成的DALY损失转化为其货币等价物。每种疾病的严重经济出血是通过将以国际美元计算的人均非健康GDP乘以特定年龄组(15-29岁、30-49岁、50-59岁)的DALY损失总数得出的。2015年,人均非卫生GDP等于人均GDP减去卫生总支出。DALYs和人均卫生总支出数据来自世界卫生组织,人均国内生产总值数据来自国际货币基金组织数据库。结果:2015年,肯尼亚15-59岁人群中减少了9405184个DALY。DALY的损失导致了29788392419 Int的GDP大出血。约48.6%的国内生产总值出血是由传染病和营养状况引起的,37.4%是由非传染病引起的,14.0%是由伤害引起的。结论:需要增加对国家卫生系统和满足基本需求(教育、食品、水、卫生、住所)的其他系统的国内外投资,以减轻疾病负担。关键词:非健康GDP、经济大出血、残疾调整生命年(DALY)
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引用次数: 5
Body and health perception for obesity in young adults 青少年肥胖的身体和健康认知
Pub Date : 2018-03-24 DOI: 10.3823/2556
R. Florêncio, Ana Caroline Andrade Oliveira, Jênifa Cavalcante dos Santos Santiago, Danilo Cunha Ribeiro, Ítalo Lennon Sales de Almeida, V. Pessoa, T. Moreira
Background: To identify the body and health perception and its relationship with obesity in a group of young adults. Methods: This is an analytical study performed on 1,073 young adults from Fortaleza, Ceara, Brazil, through a questionnaire whose data were analyzed by descriptive statistics and logistic regression. The Ethics Committee approved the study under opinion no 263.271/ 2013. Results: Results showed that women with obesity tended to perceive their condition more and evidenced greater body dissatisfaction than men. In addition, they were associated with obesity, self-perception of overweight and body satisfaction. Conclusion: Young people with obesity perceive their condition and are dissatisfied with it.
背景:了解一组年轻人的身体和健康感知及其与肥胖的关系。方法:对来自巴西塞阿拉州福塔莱萨的1073名年轻人进行问卷调查,采用描述性统计和逻辑回归分析。伦理委员会根据第263.271/ 2013号意见批准了该研究。结果:结果显示,肥胖女性比男性更容易察觉到自己的状况,并表现出更大的身体不满。此外,它们还与肥胖、自我感觉超重和身体满意度有关。结论:青少年肥胖患者认识到自己的状况,并对现状不满。
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引用次数: 1
Primary health care in leprosy, assessed by users and professionals 由使用者和专业人员评估的麻风病初级卫生保健
Pub Date : 2018-03-24 DOI: 10.3823/2563
N. A. Barboza, Viriato Campleo, A. A. Lustosa, B. Sampaio, G. Araújo
Objective: Evaluate the performance of primary health care in control of leprosy in Teresina, Brazil from the perspective of users and professionals. Methods: This cross-sectional, descriptive study involved 25 healthcare users with leprosy and 34 professionals (physicians and nurses) working in 13 municipal health units within the urban area of Teresina. The data were collected from January to June, 2017, using the Instrument for Assessing the Performance of Primary Care in Leprosy Control Actions, a document based on the Primary Care Assessment Tool/PCATool Brasil which measures the presence and extension of essential and derived attributes from primary health care. Results: The mean scores obtained for the essential, derived and global attributes, through the perception of the users, were lower than 6.6, indicating that the primary health services in Teresina are not sufficiently oriented to carry out leprosy control actions, mainly in terms of access, integrality of services provided, family orientation and community orientation. The professionals showed a contrasting view, with averages exceeding 6.6 for all attributes and scores. The difference in perception between the groups was significant for all attributes except for coordination (Mann-Whitney U test, p = 0.479).The overall evaluation of quality was not influenced by the user’s clinical or socioeconomic variables, but  rather by the organization/provision of services. Conclusions: The municipal health units within the urban area of Teresina must be strongly guided by primary health care attributes in order to reach higher levels of user satisfaction.
目的:从使用者和专业人员的角度评估巴西Teresina初级卫生保健在控制麻风病方面的表现。方法:这项横断面描述性研究涉及25名麻风病患者和34名专业人员(医生和护士),他们在Teresina市区的13个市级卫生单位工作。数据收集于2017年1月至6月,使用《评估麻风病控制行动中初级保健表现的工具》,这是一份基于初级保健评估工具/PCATool Brasil的文件,用于衡量初级保健的基本属性和衍生属性的存在和扩展。结果:通过用户的感知,基本属性、派生属性和全局属性的平均得分均低于6.6,表明Teresina的初级卫生服务在开展麻风病控制行动方面没有足够的导向性,主要是在获得服务、提供服务的完整性、家庭导向和社区导向方面。专业人士表现出了截然不同的观点,所有属性和分数的平均值都超过了6.6。除协调外,各组之间的感知差异在所有属性上都很显著(Mann-Whitney U检验,p=0.479)。质量的总体评估不受用户的临床或社会经济变量的影响,而是受服务的组织/提供的影响。结论:Teresina市区内的市级卫生单位必须以初级卫生保健属性为导向,才能达到更高水平的用户满意度。
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引用次数: 0
Perception Towards the Use of Smartphone Application (Apps) to Enhance Medication Adherence Among Saudi Pediatrics 沙特儿科对使用智能手机应用程序提高药物依从性的看法
Pub Date : 2018-03-23 DOI: 10.3823/2560
Renad Alsalamah, R. Alsuhaibani, Nadia M Maysarah
Objectives: The aim of this study was to measure the importance of smartphone applications (Apps) in medication adherence in children to help parents and caregivers in giving medication to children to maintain a good health and quality of life, and to improve current clinical practices in adherence to medications among Saudi pediatrics. Methodology: Cross sectional survey to Saudi Arabia population was conducted from March to April 2017(n=405). Data were collected, tabulated and analyzed using Survey Monkey. We present design requirements for building medication reminders that support the routine aspect of medication-taking by linking children’s concerns, (such as games) on taking medications at time. Results: Of the 405 survey participants, the majority of participants 72.5% were not aware by applications of smart device that make easier to take medicines regularly. Eighty percent of participants preferred a mobile app to help their children take the medicine easily and regularly, and 39.8% of them thought that the child will interact with this game, the majority of them 88.6% don’t have any obstacle hinders the use of these updated applications. Fifty percent of them will encourage young patients, to use such applications (App) to help them in their medication adherence. Conclusion: Nonadherence to medication is still represents a fundamental health care challenge. The presence of an application makes it easier for parents to give medication to their sick children. Most children love playing games, there is a high probability of their attachment to this application (App) and it will promote children’s medication adherence. Key words: Patient adherence, Pediatric, Smartphone, Applications, Apps.
目的:本研究的目的是衡量智能手机应用程序(Apps)在儿童药物依从性中的重要性,以帮助父母和护理人员为儿童提供药物,以保持良好的健康和生活质量,并改善沙特儿科目前在药物依从性方面的临床实践。方法:2017年3月至4月对沙特阿拉伯人口进行了横断面调查(n=405)。使用Survey Monkey对数据进行收集、制表和分析。我们提出了构建药物提醒的设计要求,通过将儿童对按时服药的担忧(如游戏)联系起来,支持日常服药。结果:在405名调查参与者中,72.5%的大多数参与者不知道智能设备的应用程序,因为它更容易定期服药。80%的参与者更喜欢手机应用程序来帮助他们的孩子轻松、定期地服药,39.8%的参与者认为孩子会与这款游戏互动,其中大多数人88.6%的人没有任何障碍阻碍使用这些更新的应用程序。其中50%的人会鼓励年轻患者使用此类应用程序(App)来帮助他们坚持服药。结论:不坚持用药仍然是一个基本的医疗保健挑战。应用程序的存在使父母更容易给生病的孩子用药。大多数孩子喜欢玩游戏,他们很可能会喜欢这个应用程序,它会促进儿童的药物依从性。关键词:患者依从性,儿科,智能手机,应用程序,应用程序。
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引用次数: 0
Community Intervention In Elderly Population: A Fall Prevention Project 老年人社区干预:预防跌倒项目
Pub Date : 2018-03-14 DOI: 10.3823/2562
Vera Lúcia Moreira Massa Coimbra, Ermelinda Marques, Cristina Alexandra Lopes Requeijo, Renata Jabour Saraiva
Objective: This article seeks to present a pilot project of community intervention that aims to prevent the occurrence of falls in the elderly in a community setting. Method: It is a prospective study in the temporal relationship, based on Health Planning, it was developed for 9 weeks in a Community Care Unit in the Northern Region of Portugal. Data collection and interventions were performed in the home of 6 of the 12 elderly being followed up at home by the nursing team. Elderly institutionalized and totally dependent were excluded. For the collection of data, an evaluation protocol was filled out using the Morse scale, validated for the Portuguese population, to assess the risk of falls.   Results: Of the elderly who underwent nursing interventions, 50% presented a high risk of falls. Epidemiological indicators show that the incidence rate of falls was 0% and the prevalence rate of falls, in the last year was, 37.5%.  Conclusion: The data collected was used for the production of epidemiological indicators, structure, process, and results. It is suggested to continue the project for one year, covering a larger sample and subsequent evaluation, and the creation of indicators for informal care providers.
目的:本文旨在介绍一个社区干预试点项目,旨在防止社区环境中老年人跌倒的发生。方法:这是一项基于健康规划的时间关系前瞻性研究,在葡萄牙北部地区的一个社区护理室开发了9周。护理团队在家中对12名老年人中的6名进行了数据收集和干预。被收容和完全依赖的老年人被排除在外。为了收集数据,使用莫尔斯量表填写了一份评估方案,并对葡萄牙人口进行了验证,以评估跌倒的风险。结果:在接受护理干预的老年人中,50%的人有跌倒的高风险。流行病学指标显示,去年跌倒发生率为0%,跌倒患病率为37.5%。结论:收集的数据可用于制定流行病学指标、结构、过程和结果。建议将该项目持续一年,涵盖更大的样本和随后的评估,并为非正规护理提供者制定指标。
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引用次数: 3
Maternal hemodynamic responses to two different types of moderate physical exercise during pregnancy: a randomized clinical trial 妊娠期间两种不同类型适度体育锻炼对产妇血流动力学的影响:一项随机临床试验
Pub Date : 2018-03-14 DOI: 10.3823/2559
J. S. Tavares, A. Melo, B. Maciel, A. Vasconcelos, J. Alves, M. Amorim
Background/Aim:  Maternal hemodynamic responses (heart rate, systolic and diastolic blood pressure) were compared during two types of moderate-intensity physical exercise. Methods:  A randomized clinical trial compared 120 pregnant women performing physical exercise on a treadmill (n=64) or stationary bicycle (n=56).  In 44 of these women (n=23 treadmill; n=21 bicycle), blood pressure was monitored for 24 hours following exercise.  Repeated-measures analysis compared maternal heart rate, systolic and diastolic blood pressure before, during and in the 24 hours following exercise in both groups.  Results:  Maternal heart rate increased significantly (p<0.001) with both types of exercise (from 84 at rest to 112 bpm on the treadmill and from 87 at rest to 107 bpm on the bicycle), without exceeding the limit of 140 bpm.  Systolic pressure increased from 110 at rest to 118 mmHg on the bicycle (p=0.06) and from 112 at rest to 120 mmHg on the treadmill (p=0.02).  Systolic pressure dropped steadily following exercise, reaching its lowest level (104 mmHg) after 14 hours, increasing thereafter and returning to pre-exercise levels by the 19th hour.  Diastolic pressure increased during exercise irrespective of the type of exercise (p=0.27), from 70 at rest to 75 mmHg on the bicycle (p=0.39) and from 70 at rest to 76 mmHg on the treadmill (p=0.18), with the lowest level (59 mmHg) being at the 13th hour. Conclusions:  A slight increase in blood pressure levels was found during exercise; however, this was not clinically significant and was followed by a substantial hypotensive effect that lasted around 19 hours. Register: Clinical Trials NCT01383889.
背景/目的:比较母亲在两种中等强度体育锻炼中的血液动力学反应(心率、收缩压和舒张压)。方法:一项随机临床试验比较了120名在跑步机(n=64)或固定自行车(n=56)上进行体育锻炼的孕妇。其中44名女性(n=23跑步机;n=21自行车)在运动后24小时内监测血压。重复测量分析比较了两组孕妇在运动前、运动中和运动后24小时内的心率、收缩压和舒张压。结果:母亲的心率在两种类型的运动中都显著增加(p<0.001)(在跑步机上从休息时的84次/分增加到112次/分,在自行车上从休息的87次/分提高到107次/分),但没有超过140次/分的限值。自行车上的收缩压从休息时的110毫米汞柱增加到118毫米汞柱(p=0.06),跑步机上的收缩压力从静止时的112毫米汞柱上升到120毫米汞柱。运动后收缩压稳步下降,14小时后达到最低水平(104毫米汞柱),此后增加,到第19小时恢复到运动前的水平。无论运动类型如何,舒张压在运动过程中都会增加(p=0.27),在自行车上从静止时的70毫米汞柱增加到75毫米汞柱(p=0.39),在跑步机上从休息时的70 mmHg增加到76毫米汞柱,p=0.18),最低水平(59毫米汞柱)出现在第13小时。结论:运动时血压水平略有升高;然而,这在临床上并不显著,随后出现了持续约19小时的显著降压效果。注册号:临床试验NCT01383889。
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引用次数: 1
Maternal-fetal acute responses to two moderate-intensity exercise types: a randomized clinical trial 两种中等强度运动类型的母婴急性反应:一项随机临床试验
Pub Date : 2018-03-14 DOI: 10.3823/2558
J. S. Tavares, A. Melo, S. Leite, A. Silva, J. Alves, V. O. Barros, A. Ramos, M. Amorim
Objective:  This study aims to compare maternal and fetal responses during two physical exercise types. Design:  A randomized clinical trial compared 120 pregnant women, gestational age of 35-37 weeks, 56 exercising on a stationary bicycle (Group A) and 64 on a treadmill (Group B). Methods: Participants were monitored for three 20-minute phases: resting, exercise and recovery.  Fetal heart rate (FHR) and maternal heart rate (MHR) were monitored.  Glucose and lactate levels were evaluated at rest and during exercise. Results:  After the beginning of exercise, maximum lactate (L) levels were reached at 20 minutes and never exceeded 4 mmol/l.  FHR decreased by 22 bpm during exercise in relation to resting values, irrespective of the exercise type (p 0.05), increasing at 20’ to 32% and 40.6%, respectively, (p>0.05).  The FHR decrease during exercise was accompanied by a simultaneous increase in its variability (p<0.001), nevertheless a rapid return to resting values was observed shortly after exercise end.  Glucose decreased in both groups irrespective of the exercise type (85 mg/dl at rest; 79 mg/dl during exercise and 81 mg/dl during recovery; p<0.001). There were no hypoglycemia cases. Conclusions: FHR variability increase and the rapid return to resting values after exercise suggests that the FHR fall and the presence of bradycardia during exercise is the fetal physiologic response to blood flow redistribution, with maintenance of fetal well-being. Key-words: Exercise; fetal heart rate; glucose; maternal heart rate; pregnancy Clinical Trial Registration: ClinicalTrials.gov, www.clinicaltrials.gov, NCT01383889.
目的:比较两种体育锻炼方式对母体和胎儿的影响。设计:一项随机临床试验比较了120名孕妇,孕龄为35-37周,56名在固定自行车上锻炼(A组),64名在跑步机上锻炼(B组)。方法:对参与者进行了三个20分钟的监测阶段:休息,运动和恢复。监测胎儿心率(FHR)和产妇心率(MHR)。在休息和运动时评估葡萄糖和乳酸水平。结果:运动开始后,乳酸(L)在20分钟达到最大值,从未超过4 mmol/ L。与静息值相比,无论运动类型如何,运动期间FHR下降了22 bpm (p < 0.05),分别增加了32%和40.6% (p < 0.05)。运动期间的FHR下降伴随着其变异性的同时增加(p<0.001),然而在运动结束后不久观察到快速恢复到静息值。无论运动类型如何,两组血糖均下降(休息时85 mg/dl;运动时79 mg/dl,恢复时81 mg/dl;p < 0.001)。无低血糖病例。结论:运动后FHR变异性增加并迅速恢复到静息值,提示运动时FHR下降和心动过缓是胎儿对血流再分配的生理反应,维持胎儿健康。关键词:却锻炼;胎儿心率;葡萄糖;产妇心率;妊娠临床试验注册:ClinicalTrials.gov, www.clinicaltrials.gov, NCT01383889。
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引用次数: 1
The Effect of Deep Oscillation Therapy in Fibrocystic Breast Disease. A Randomized Controlled Clinical Trial 深层振荡治疗乳腺纤维囊性疾病的疗效。随机对照临床试验
Pub Date : 2018-02-27 DOI: 10.3823/2555
S. Hernández, M. Fernandez, Y. Iturralde, A. S. Fernández
Introduction: Fibrocystic breast disease is the most widespread disorder in women during their phase of sexual maturity. Deep oscillation (DO) therapy has been used on patients who have undergone an operation for breast cancer as a special form of manual lymphatic drainage. Method: Experimental, prospective case-control studies were conducted in 401 women diagnosed with fibrocystic breast disease. The sample was selected at random and was divided into three groups, a study group and two control groups. Results: Pain was reduced in the three therapies applied. This was statistically significant in the study group. The sonography study presented a predominance of its fibrous form. Upon completion of the treatment a resolution of the fibrosis was observed in the study group. The women were using their bra in an incorrect manner. Conclusions: Pain was reduced in the three therapies applied. In the study group this reduction was statistically significant. It is possible to verify the magnitude of the resonant vibration in the connective tissue from surface to deep layers by viewing the effect of the deep oscillations through the use of diagnostic ultrasound. The most frequent sonographic finding was fibrosis. Deep oscillation therapy produces a tissue-relaxing, moderate vasoconstriction effect, favours local oedema reabsorption and fibrosis reduction. A factor that may affect breast pain is incorrect bra use. The majority of women studied were using their bra incorrectly.
简介:纤维囊性乳腺疾病是女性在性成熟阶段最普遍的疾病。深振荡(DO)疗法已被用于乳腺癌手术患者作为一种特殊形式的手工淋巴引流。方法:对401例诊断为纤维囊性乳腺疾病的女性进行了实验性、前瞻性病例对照研究。随机选取样本,分为三组,研究组和对照组。结果:三种治疗方法均能减轻疼痛。这在研究组中具有统计学意义。超声检查显示其纤维形态占优。治疗结束后,观察到研究组的纤维化消退。这些女性使用胸罩的方式不正确。结论:三种治疗方法均能减轻疼痛。在研究组中,这种减少在统计学上是显著的。通过使用诊断超声观察深层振荡的影响,可以验证结缔组织中从表层到深层的共振振动的大小。最常见的超声检查结果是纤维化。深度振荡治疗产生组织松弛,适度的血管收缩作用,有利于局部水肿重吸收和纤维化减少。一个可能影响乳房疼痛的因素是不正确使用胸罩。大多数被调查的女性都没有正确使用胸罩。
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引用次数: 4
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International archives of medicine
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