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Prevalence of Anemia Among Pregnant Women in Rural Village of Sindhupalchowk District of Nepal - A Cross-Sectional Study 尼泊尔Sindhupalchowk地区农村孕妇贫血患病率的横断面研究
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1777
Biyas Thapa, Smriti Bohara, Sistu Kc, M. Sapkota, Bibek Dhakal, Binod Gaire
Background: Anemia is a global public health problem all around the world, principally the developing countries like Nepal. Anemia results in maternal mortality alongside low birth weight which contributes to an increased infant mortality rate. The prevalence of anemia ranges from 27% to 42% among pregnant women depending on geographical regions. Iron and folic acid tablets are supplied free of charge to pregnant women as part of the Nepal government's National Anemia Control Strategy and Iron Intensification Program. Methods:  A cross-sectional study was carried out among pregnant women attending Manekharka health center for an antenatal checkup. Hemoglobin levels of pregnant women from April 2018-2020 were obtained and analyzed. Hemoglobin level was determined using the indirect cyanmethemoglobin method.Results:  We used the World Health Organization (WHO) standard classification of hemoglobin levels below 11 gm/dl to determine the prevalence of anemia in pregnant women. The result suggested that a total of 30.7%, (n=63) of the pregnant women were anemic. Among which 4.76% had moderate anemia (hemoglobin 7-9.9gm/dl) and 96.58% had mild anemia (hemoglobin ≥9.9mg/dl to <11gm/dl).Conclusion:  The study and its results suggest that the women in the age group 16-19 had a higher prevalence of anemia whereas the age group 25-29 had the lowest prevalence of anemia. Moreover, the study revealed that the prevalence of anemia in hills is substantial.
背景:贫血是一个全球性的公共卫生问题,在世界各地,主要是发展中国家,如尼泊尔。贫血导致产妇死亡,同时出生体重过低,导致婴儿死亡率上升。根据地理区域的不同,孕妇贫血的患病率从27%到42%不等。作为尼泊尔政府国家贫血控制战略和铁强化方案的一部分,向孕妇免费提供铁和叶酸片。方法:采用横断面研究方法,对在马内克哈尔卡保健中心进行产前检查的孕妇进行调查。获取2018-2020年4月孕妇血红蛋白水平并进行分析。采用间接氰高铁血红蛋白法测定血红蛋白水平。结果:我们使用世界卫生组织(WHO)血红蛋白水平低于11 gm/dl的标准分类来确定孕妇贫血的患病率。结果显示,30.7% (n=63)孕妇贫血。其中4.76%为中度贫血(血红蛋白7 ~ 9.9gm/dl), 96.58%为轻度贫血(血红蛋白≥9.9mg/dl ~ <11gm/dl)。结论:该研究及其结果表明,16-19岁年龄组的妇女贫血患病率较高,而25-29岁年龄组的妇女贫血患病率最低。此外,研究显示,贫血的患病率在丘陵是实质性的。
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引用次数: 0
Knowledge, Attitude, and Perception of Tobacco Harm Reduction Strategies Among Medical Students in Southwest, Nigeria 尼日利亚西南部医学生对减少烟草危害策略的知识、态度和认知
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1766
I. Dike, Uzochukwu Eustace Imo, Jeremiah Adepoju Moyondafoluwa
Background: The rate of tobacco use is on a steady increase worldwide and is associated with over 7 million deaths per year, three-quarters of which occur in low-and middle-income countries. Inadequate cessation programs/interventions, difficulties quitting tobacco, and a lack of information about tobacco health risks and tobacco harm reduction methods, have all contributed to the rapid rise of tobacco use in Nigeria, with the country's smoking rate increasing at a rate of approximately 4% each year. Tobacco harm reduction (THR) methods are alternatives to cigarette smoking that have been shown to assist in smoking cessation and reduce the mortality and morbidity associated with tobacco and nicotine use, however, these methods are still controversial and have drawn some criticism in recent times. Due to the prevalence of THR methods among young people and the growing health debate around them, medical students are likely to have a direct or indirect encounter with THR methods. A greater grasp of their viewpoint is beneficial while training them. Therefore, this study aims to determine the knowledge, attitude, and perception of THR strategies among medical students in southwest, Nigeria.Methods: A cross-sectional study was carried out among clinical medical students in 6 medical schools in southwest, Nigeria, and data was collected via an online semi-structured based questionnaire. Descriptive analysis was done and a chi-square test was used to test the association between the level of knowledge of tobacco health risks and the socio-demographic variables.Results: 199 participants’ data were fully collected, 105(53%) were male while 94(47%) were female. Most (79%) of the respondents were of the age group 21-25. The majority (99.5%) of them never smoked. The majority of the participants 190(95%) have good knowledge about the health risks of tobacco and a Chi-square test showed only age as a significant socio-demographic variable, with participants between the 16-20 age group having a higher frequency of poor knowledge. Only 83(42%) understood what THR means. Also, 185(93%) do not know about THR methods regulation in Nigeria. 179(90%) have an interest in knowing about THR and 147(74%) said they will recommend it to smokers as a future doctor. 60.3% of participants perceived THR products to be less harmful than conventional cigarettes and 23% perceived THR products to be harmful to people in the vicinity of the users. 50.8% of participants see THR products to be a “gateway” to conventional cigarette use in the future.Conclusion: From this result, most medical students have good knowledge about tobacco harm risks, therefore, they will be able to confidently discuss this topic with patients and the public. However, there is poor knowledge of THR methods among medical students. This highlights the critical need to further educate medical students as well as give evidence-based recommendations at all levels to assist in advising patients who enquire or
背景:烟草使用率在世界范围内稳步上升,每年与700多万人死亡有关,其中四分之三发生在低收入和中等收入国家。戒烟规划/干预措施不足、戒烟困难以及缺乏有关烟草健康风险和减少烟草危害方法的信息,都是导致尼日利亚烟草使用迅速增加的原因,该国的吸烟率每年以约4%的速度增长。减少烟草危害(THR)方法是吸烟的替代方法,已被证明有助于戒烟并降低与烟草和尼古丁使用相关的死亡率和发病率,然而,这些方法仍然存在争议,并在最近引起了一些批评。由于THR方法在年轻人中的流行以及围绕这些方法的健康辩论日益增多,医学生很可能直接或间接地接触到THR方法。在训练他们的时候,更好地掌握他们的观点是有益的。因此,本研究旨在了解奈及利亚西南部医学生对THR策略的认知、态度和认知。方法:对尼日利亚西南部6所医学院临床医学生进行横断面研究,采用半结构化在线问卷收集数据。进行描述性分析,并使用卡方检验来检验烟草健康风险知识水平与社会人口变量之间的关联。结果:199名受试者的资料被完整收集,其中男性105人(53%),女性94人(47%)。大多数(79%)的受访者年龄在21-25岁之间。他们中的大多数(99.5%)从不吸烟。大多数参与者190(95%)对烟草的健康风险有很好的了解,卡方检验显示,只有年龄是一个重要的社会人口变量,16-20岁年龄组的参与者知识贫乏的频率更高。只有83人(42%)理解THR的含义。此外,185人(93%)不知道尼日利亚对THR方法的规定,179人(90%)有兴趣了解THR, 147人(74%)表示他们会将其推荐给吸烟者作为未来的医生。60.3%的参与者认为THR产品比传统卷烟危害小,23%的参与者认为THR产品对使用者附近的人有害。50.8%的参与者认为THR产品是未来使用传统卷烟的“入口”。结论:从这个结果来看,大多数医学生对烟草危害风险有很好的认识,因此他们能够自信地与患者和公众讨论这个话题。然而,医学生对THR方法的了解程度较低。我们的研究发现,大多数医学生都有兴趣了解THR方法,因此我们需要进一步教育医学生,并在各个层面提供基于证据的建议,以协助向询问或对THR产品感兴趣的患者提供建议,并规范其在一般社区中的使用。
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引用次数: 0
A Case of Haemorrhagic Herpes Zoster 出血性带状疱疹1例
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1804
P. Kuwar Chhetri, A. Montasir, Renu Gupta, Shamsul Alam, Shafwanur Rahman, Fahim Rahman
Background: Varicella-zoster virus (HHV3) is one of the virus in herpes family. Herpes zoster results from the reactivation of varicella-zoster virus in the dorsal root ganglion. This reactivation occurs in immunocompromised conditions such as people with cancer, organ transplant recipients or those receiving chemotherapy, and people with HIV. Old age is also an important risk for the development of herpes zoster. Immunocompromised patients are at increased risk of VZV reactivation because of reduced T cell-mediated immunity. Emotional stress has also been mentioned as an associated factor in people with herpes zoster. The Classic clinical presentation consists of clear vesicular eruptions in dermatomal distribution which are painful. An immunocompromised individual may have frequent attacks of herpes zoster, cutaneous dissemination, organ involvement, and hemorrhagic herpes zoster. Haemorrhagic herpes zoster is an atypical form of herpes zoster develops in patients who are immunosuppressed and people of advanced age who are taking antiplatelets, and anticoagulants, and also in patients with thrombocytopenia due to any cause.  The most common Association of herpes zoster is observed with lymphocytic leukemia and less frequently with myeloid leukemia. Management icludes antiviral therapy along with management of haemorrhagic conditions.Case Report: A nondiabetic male of 60 years attended the medicine outpatients department with complaints of epistaxis for two days. No history of bleeding from other sites was evident. There was no history of trauma or taking of anticoagulants or antiplatelets. No history of fever. The patient was anaemic and an erythematous rash was evident along the right T6 dermatome. He was admitted to the general medicine ward. On the second day of his admission, our patient developed painful haemorrhagic bullous lesions over the right T6 dermatome resembling a bunch of grapes and erythematous popular lesions all over his body (Figure 1). The bullous lesions became larger in size in the subsequent two days of admission. On query, he mentioned that he had suffered from Varicella Zoster in his early childhood. Patients haemoglobin was 10.70 gm/dl, total count of white blood cell (WBC) was 13.20 K/ mm3 (normal value 4.00 – 11.00 K/ mm3), neutrophil and lymphocyte counts were 2.38 K/ mm3 (normal value 2.16 – 6.04 K/ mm3) and 10.38 K/ mm3 (normal value 0.6 – 3.06 K/ mm3) respectively. His platelet count was 5.00 K/ mm3 (normal value 150.00 – 400.00 K/ mm3). The patient denied skin biopsy. A diagnosis of haemorrhagic herpes zoster was made after a dermatology consultation and oral valacyclovir was started along with oral and topical antibiotics and regular dressings. After six units of platelet transfusion patients, the platelet count was raised to 30 K/ mm3. Peripheral blood film was suggestive of acute leukaemia. A bone marrow examination was suggestive of acute myeloid leukaemia. The patient was transferred to the haemato-oncolog
背景:水痘带状疱疹病毒(HHV3)是疱疹科的一种病毒。带状疱疹是由水痘带状疱疹病毒在背根神经节重新激活引起的。这种再激活发生在免疫功能低下的情况下,如癌症患者、器官移植接受者或接受化疗的人,以及艾滋病毒感染者。老年也是带状疱疹发病的一个重要风险因素。免疫功能低下的患者由于T细胞介导的免疫力降低,VZV再激活的风险增加。情绪压力也被认为是带状疱疹患者的一个相关因素。典型的临床表现包括皮肤分布的清晰水疱性皮疹,令人疼痛。免疫功能低下的个体可能有频繁的带状疱疹发作、皮肤播散、器官受累和出血性带状疱疹。出血性带状疱疹是带状疱疹的一种非典型形式,发生于免疫抑制患者和服用抗血小板和抗凝剂的高龄患者,也发生于任何原因导致的血小板减少患者。带状疱疹与淋巴细胞白血病最常见,与髓性白血病的联系较少。治疗包括抗病毒治疗和出血情况的处理。病例报告:男性,60岁,非糖尿病患者,以鼻出血主诉就诊内科门诊2天。其他部位无明显出血史。没有外伤史,也没有服用过抗凝血剂或抗血小板药物。无发热史。患者贫血,右侧T6皮肤区有明显的红斑。他住进了普通内科病房。入院第二天,患者右侧T6皮区出现疼痛的出血性大疱性病变,形似一串葡萄,全身出现红斑性流行病变(图1)。在随后的入院两天内,大疱性病变体积变大。在被问及时,他提到他在幼年时患过水痘。患者血红蛋白10.70 gm/dl,白细胞总数13.20 K/ mm3(正常值4.00 ~ 11.00 K/ mm3),中性粒细胞和淋巴细胞计数分别为2.38 K/ mm3(正常值2.16 ~ 6.04 K/ mm3)和10.38 K/ mm3(正常值0.6 ~ 3.06 K/ mm3)。血小板计数5.00 K/ mm3(正常值150.00 ~ 400.00 K/ mm3)。病人否认皮肤活检。在皮肤科会诊后,诊断为出血性带状疱疹,并开始口服伐昔洛韦,同时使用口服和局部抗生素和常规敷料。患者输血小板6个单位后,血小板计数升高至30 K/ mm3。外周血膜提示急性白血病。骨髓检查提示急性髓性白血病。患者被转移到血液肿瘤病房进行进一步的规划和管理。结论:出血性带状疱疹可在不同的临床条件下发生,急性髓性白血病虽然罕见,但也是其中一种。在这种情况下,临床情况以及骨髓和血液图像有助于达到诊断。
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引用次数: 0
Myasthenia Gravis Exacerbation Following COVID-19 Vaccine: A Case Report COVID-19疫苗后重症肌无力加重1例报告
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1741
Thoybah Yousif Ibrahim Gabralla, H. Bashir, O. Mohamed
Background: As of December 2021, the World Health Organization (WHO) reports that Coronavirus disease 2019 (COVID-19) led to about 5,403,662 deaths. While COVID-19 has resulted in millions of deaths worldwide to date, vaccination remains the mainstay of infection control. AZD1222 (AstraZeneca vaccine) was distributed in Sudan by the COVID-19 Vaccines Global Access facility in March 2021. It was added to the emergency use list by WHO in the middle of February 2021. However, vaccine safety among patients with autoimmune diseases, such as myasthenia gravis (MG), is yet to be established. MG is a relatively rare illness that could result in life-threatening complications. Myasthenic crisis is considered the most serious complication of MG that can lead to death due to aspiration and respiratory failure. Plasma exchange (PLEX), Immunoadsorption (IA), and intravenous Immunoglobulin (IVIG) are the first-line treatment for myasthenic crisis. It is proven that cortisone has a positive effect when used as add-on therapy with PLEX/IA and IVIG.   The case: We report the case of a 37-year-old Sudanese female who presented to the emergency room with an exacerbation of her previously well-controlled MG following her second dose of AZD1222 vaccination. The exacerbation symptoms at time of presentation were severe generalized body weakness that increasing overtime and shortness of breath. Computerized tomography of the chest was performed, and it revealed no evidence of COVID-19. Management at the ER started with rehydration and IV methylprednisolone 1g, followed by IV hydrocortisone 200mg. She continued to deteriorate and was admitted to the intensive care unit where she was intubated and placed on a mechanical ventilator. IVIG was requested but couldn't be obtained due to the low-income setting, and fourteen days after admission patient died due to circulatory collapse. Our study aims to present an MG case with features of MG exacerbation following the administration of the second dose of AZD1222.   Conclusion: Little is known about the effect of different COVID-19 vaccines on subgroups of patients with autoimmune diseases like MG. Although the safety profile of AZD1222 is generally reassuring, people with severe underlying diseases were excluded from trials. Therefore, more efforts and experimental studies may be needed, with closer vigilance in MG patients. It has not been elucidated how the COVID-19 vaccine might provoke autoimmunity, but several theories have been proposed. Molecular mimicry theory can explain how the genetic material of a virus could provoke autoimmunity, it describes the cross-reactivity of antibodies produced against proteins that are encoded by viral genetic material with the proteins located at the post-synaptic membrane. There is a debate about whether vaccine benefit outweighs the risk in MG patients or not. However, we believed that MG patients should be informed about the benefit and risks of COVID-19 vaccination.  
背景:截至2021年12月,世界卫生组织(世卫组织)报告称,2019年冠状病毒病(COVID-19)导致约5,403,662人死亡。虽然COVID-19迄今已在全球造成数百万人死亡,但疫苗接种仍然是感染控制的主要手段。AZD1222(阿斯利康疫苗)由COVID-19疫苗全球可及基金于2021年3月在苏丹分发。世卫组织于2021年2月中旬将其列入紧急使用清单。然而,疫苗在自身免疫性疾病(如重症肌无力)患者中的安全性尚未确定。MG是一种相对罕见的疾病,可能导致危及生命的并发症。肌无力危象被认为是MG最严重的并发症,可因误吸和呼吸衰竭而导致死亡。血浆置换(PLEX)、免疫吸附(IA)和静脉注射免疫球蛋白(IVIG)是肌无力危象的一线治疗方法。已证明可的松作为PLEX/IA和IVIG的附加治疗具有积极作用。病例:我们报告了一名37岁苏丹女性的病例,她在第二次接种AZD1222疫苗后,因先前控制良好的MG加重而出现在急诊室。发病时的加重症状为严重的全身无力,持续时间延长,呼吸急促。对胸部进行了计算机断层扫描,没有发现COVID-19的证据。急诊室的治疗开始于补液和静脉注射甲基强的松1g,随后静脉注射氢化可的松200mg。她的病情继续恶化,被送进重症监护室,在那里插管并戴上了机械呼吸机。入院后14天,患者因循环衰竭死亡。我们的研究旨在介绍一个MG病例,在服用第二剂AZD1222后出现MG加重的特征。结论:不同COVID-19疫苗对MG等自身免疫性疾病患者亚群的影响尚不清楚。虽然AZD1222的安全性总体上令人放心,但患有严重基础疾病的患者被排除在试验之外。因此,可能需要更多的努力和实验研究,对MG患者更密切的警惕。目前尚不清楚COVID-19疫苗如何引发自身免疫,但已经提出了几种理论。分子模仿理论可以解释病毒的遗传物质如何引起自身免疫,它描述了针对病毒遗传物质编码的蛋白质产生的抗体与位于突触后膜的蛋白质的交叉反应性。关于疫苗对MG患者的益处是否大于风险,存在争议。然而,我们认为MG患者应该被告知COVID-19疫苗接种的益处和风险。
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引用次数: 1
Awareness, Knowledge, Attitude, and Skills Regarding Telemedicine Among Syrian Healthcare Providers During the COVID-19 Pandemic: A Cross-Sectional Study 在2019冠状病毒病大流行期间,叙利亚医疗保健提供者关于远程医疗的意识、知识、态度和技能:一项横断面研究
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1774
Hidar Alibrahim, S. Swed, H. Bohsas, S. Shoib, S. Alsakka, Nagham Jawish, Zain Alabdeen Othman, B. Sawaf
Background: After the widespread of COVID-19 around the globe, it was imperative to establish preventative measures to restrict the virus's transmission and enable clinicians to remotely monitor patients' status and avoid direct contact with them. The purpose of this research was to present an overview of the awareness, knowledge, attitude, and abilities of Syrian physicians about telemedicine technology.Methods: An online cross-sectional study was conducted from 1 April to 15 May, 2022 to assess Syrian doctors' awareness, knowledge, attitude, and skills towards telemedicine. The questionnaire was taken from published study, and the inclusion criteria consist the Syrian doctors who worked in hospitals during the COVID19 pandemic, mainly those who had direct contact with patients. Data were analyzed using descriptive and multivariate logistic regression analysis in IBM, SPSS V. 28.0.Results: Among 385 responses, 52.72% of them were females, 83.9% of them were aged less than 30 years old, and 66% were working in the governmental sector. 66% of participants have moderate knowledge about using computers and the internet, 80% have heard about telemedicine. Despite that, 95.1% of participants have not attended any training workshop on telemedicine, and most of them have reported no availability of a telemedicine unit in their department. Only 31.7% participants have shown high awareness of telemedicine. Furthermore, no significant correlation was identified between the academic level with the age and telemedicine awareness, knowledge, attitude, or computer skills. Despite that, there was an obvious correlation between age and computer skills (P Value<0.05). There was a significant correlation between the medical specialty and awareness, and computer abilities, especially the anesthesiology (88.5±5.2), (84±8.7) respectively.Conclusion: The study results demonstrate that most of the participating clinical doctors have a neutral view of telemedicine, even though they don't know much about it and don't have considerable experience with it. It is practical to educate and train academic staff, practicing physicians, residents and medical students within the clinical stages about telemedicine.
背景:在COVID-19在全球广泛传播后,必须制定预防措施以限制病毒的传播,并使临床医生能够远程监测患者的状态并避免与患者直接接触。本研究的目的是概述叙利亚医生对远程医疗技术的认识、知识、态度和能力。方法:于2022年4月1日至5月15日进行了一项在线横断面研究,以评估叙利亚医生对远程医疗的意识、知识、态度和技能。问卷取自已发表的研究成果,纳入标准为在2019冠状病毒病大流行期间在医院工作的叙利亚医生,主要是与患者直接接触的医生。采用IBM、SPSS V. 28.0软件进行描述性和多变量logistic回归分析。结果:385名受访者中,女性占52.72%,年龄在30岁以下的占83.9%,在政府部门工作的占66%。66%的参与者对使用计算机和互联网有一定的了解,80%的人听说过远程医疗。尽管如此,95.1%的参与者没有参加过任何远程医疗培训讲习班,其中大多数人报告说,他们所在部门没有远程医疗单位。只有31.7%的受访者对远程医疗有较高的认识。此外,学术水平与年龄与远程医疗意识、知识、态度或计算机技能之间没有显著的相关性。尽管如此,年龄与计算机技能之间存在明显的相关性(P值<0.05)。医学专业与意识、计算机能力有显著相关性,以麻醉学(88.5±5.2)、(84±8.7)显著。结论:研究结果表明,大多数参与的临床医生对远程医疗的看法是中立的,尽管他们对远程医疗的了解并不多,也没有足够的经验。在临床阶段对学术人员、执业医师、住院医师和医学生进行远程医疗教育和培训是可行的。
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引用次数: 0
The Effect of Music Intervention on Anxiety and Pain During Cesarean Delivery: A Meta-Analysis of 1513 Patients 音乐干预对剖宫产患者焦虑和疼痛的影响:1513例患者的荟萃分析
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1812
A. Khaity, Mohammed Tarek, Y. Alabdallat, K. Albakri, M. Gabra, Hazem. S Ghaith
Background:  A cesarean section (CS) is one of the most common operations globally, with an estimated 18.5 million surgical procedures each year. Accordingly, music therapy has become a trendy possible solution in many clinical conditions and surgical procedures. However, most previous studies have shown conflicting findings regarding the efficacy of music in reducing pain and anxiety in women with cesarean delivery. Therefore, in this meta-analysis, we aimed to investigate whether music intervention has a beneficial effect on preoperative, intraoperative, and postoperative anxiety, pain, and vital signs in women with cesarean section.Method: We conducted a comprehensive search of Scopus, Web of Science, PubMed, and Cochrane Central was conducted for relevant randomized controlled trials (RCTs) from inception until August 2022. Data were extracted from eligible studies and pooled as standardized mean difference (SMD) or mean difference (MD) values in a random-effect model meta-analysis, using RevMan software. All the steps of this study were performed according to the PRISMA statement guidelines.Results: Thirteen RCTs were included in this meta-analysis with a total of 1513 patients. Our study showed that music was superior to control in terms of overall anxiety score (SMD = - 0.26, 95% CI [- 0.39, - 0.14], p <0.0001), postoperative pain (SMD = - 0.50, 95% CI [- 0.74, - 0.26], p < 0.0001), and the overall effect of diastolic blood pressure (DBP) (MD = -1.58, 95% CI [- 3.11, - 0.04], p = 0.04). The overall effect did not favor either of the two groups in terms of systolic blood pressure (SBP) and heart rate ((MD = - 1.87, 95% CI [-4.04, 0.30], p = 0.09), (MD = - 2.10, 95% CI [- 4.78, 0.58], p = 0.12); respectively).Conclusion: Ultimately, the current evidence supports using music to alleviate the anxiety and pain of women during and after cesarean sections. In addition, our analysis revealed that music has a beneficial effect on DBP and intraoperative heart rate over control in patients with CS. However, the music did not differ significantly from the placebo in preoperative anxiety, postoperative heart rate, as well as SBP. Future RCTs are recommended to confirm the efficacy of music in the preoperative period and vital signs among women undergoing cesarean section.
背景:剖宫产(CS)是全球最常见的手术之一,每年估计有1850万例手术。因此,音乐疗法在许多临床条件和外科手术中已经成为一种可能的解决方案。然而,关于音乐在减轻剖宫产妇女疼痛和焦虑方面的功效,大多数先前的研究都显示了相互矛盾的结果。因此,在本荟萃分析中,我们旨在探讨音乐干预是否对剖宫产妇女术前、术中和术后的焦虑、疼痛和生命体征有有益的影响。方法:全面检索Scopus、Web of Science、PubMed和Cochrane Central,检索自成立至2022年8月的相关随机对照试验(RCTs)。数据从符合条件的研究中提取,并使用RevMan软件在随机效应模型荟萃分析中汇总为标准化平均差(SMD)或平均差(MD)值。本研究的所有步骤均按照PRISMA声明指南进行。结果:本荟萃分析纳入13项随机对照试验,共1513例患者。我们的研究表明,音乐在总体焦虑评分(SMD = - 0.26, 95% CI [- 0.39, - 0.14], p <0.0001)、术后疼痛(SMD = - 0.50, 95% CI [- 0.74, - 0.26], p <0.0001)和舒张压(DBP)的总体影响(MD = -1.58, 95% CI [- 3.11, - 0.04], p = 0.04)方面优于对照组。在收缩压(SBP)和心率方面,总体效果对两组均不利(MD = - 1.87, 95% CI [-4.04, 0.30], p = 0.09), (MD = - 2.10, 95% CI [- 4.78, 0.58], p = 0.12);分别)。结论:最终,目前的证据支持使用音乐来减轻妇女在剖宫产期间和之后的焦虑和痛苦。此外,我们的分析显示,音乐对CS患者的舒张压和术中心率的控制有有益的影响。然而,在术前焦虑、术后心率和收缩压方面,音乐与安慰剂没有显著差异。建议未来的随机对照试验,以确认音乐在剖宫产妇女术前和生命体征的疗效。
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引用次数: 0
Simulation Based Peer-Assisted Learning: Peripheral Venous Catheterization and Blood Sampling 基于模拟的同伴辅助学习:外周静脉置管和血液采样
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1796
Didina Cătălina Barbălată, C. Toma
Background Peripheral venous catheterization (PVC) and blood sampling (BS) represent some of the first basic techniques that a medical student learns when starting clinical practice. As they are invasive maneuvers, there is a level of self-doubt that can be overcome through practice in a simulated setting. Peer-assisted medical simulation learning is an innovative educational technique that allows students to gain confidence in conducting clinical maneuvers in a safe environment. Simulation based learning focuses on trial and error, participants being able to approach the technique multiple times, without the risk of hurting a real patient. Additionally, the fact that the workshop is conducted by fellow students, creates a more comfortable learning setting.   Aim of study Our aim is to determine the effectiveness of medical simulation in learning to perform PVC and BS and in increasing the level of confidence of the participants.   Materials and methods Our study was conducted at the Department of Medical Simulation of the Center for Innovation and e-Health (CIeH), part of the University of Medicine and Pharmacy “Carol Davila” Bucharest, Romania, between March and December 2021. During this period, 2186 first year students took part in a peer-conducted simulation workshop, conducted by undergraduate medical students in all years of studies, who had previously undergone extensive training and evaluation. The aim of the workshop was to learn the basics in PVC and BS in a controlled environment. Through a questionnaire, we collected data regarding knowledge acquisition and auto-evaluation of the students’  skill and knowledge prior and after the training on a five-point scale. At the beginning of the questionnaire we obtained informed consent from the study participants.   Results The response rate to the questionnaire was 66,10%. The participants obtained an average score of 60%. There were few participants that did not acquire enough information in order to answer correctly to the questionnaire. 80% of the respondents answered accurately on 2 out of 3 questions. We observed a 48,35% increase in the confidence level of participants regarding clinical knowledge and skill acquisition after the workshop. Prior to the workshop, only 10% of participants self-evaluated with a score of 4 or 5, compared to 85% of respondents after the workshop.   Conclusions The medical simulation training led to a significant rise in students’ confidence and a high impact on the development of skill and knowledge. Through our basic workshops we want to familiarize the participants with the clinical environment, additional knowledge and skills being acquired once throughout their studies. The workshop's objective of increasing participants’ comfort regarding basic clinical techniques, such as blood sampling and peripheral venous catheterization, was accomplished. The outcome of the study enables us to adapt the curriculum and testing procedures to better me
外周静脉导管(PVC)和血液取样(BS)是医科学生在开始临床实践时首先学习的一些基本技术。因为它们是侵入性的操作,有一定程度的自我怀疑可以通过在模拟环境中的练习来克服。同伴辅助医学模拟学习是一种创新的教育技术,可以让学生在安全的环境中获得进行临床演习的信心。基于模拟的学习侧重于试错,参与者能够多次接近该技术,而不会有伤害真正病人的风险。此外,工作坊由同学主持,创造了一个更舒适的学习环境。研究目的我们的目的是确定医学模拟在学习执行PVC和BS以及增加参与者信心水平方面的有效性。材料和方法我们的研究于2021年3月至12月在罗马尼亚布加勒斯特医学和药学“Carol Davila”大学创新和电子卫生中心(CIeH)医学模拟部进行。在此期间,有2186名一年级学生参加了由同侪主持的模拟讲习班,讲习班由所有年级的医科本科生主持,这些学生以前接受过广泛的培训和评价。研讨会的目的是在受控环境中学习PVC和BS的基础知识。通过问卷调查,我们收集了学生在培训前后的知识获取和技能知识自动评估的数据。在问卷调查的开始,我们获得了研究参与者的知情同意。结果问卷回复率为66.10%。参与者的平均得分为60%。很少有参与者没有获得足够的信息来正确回答问卷。80%的受访者准确回答了3个问题中的2个。我们观察到,在研讨会后,参与者对临床知识和技能习得的信心水平提高了48.35%。在研讨会之前,只有10%的参与者自我评估得分为4或5,而在研讨会之后,85%的受访者自我评估得分为4或5。结论医学模拟训练使学生的自信心明显增强,对技能和知识的发展有较大影响。通过我们的基础研讨会,我们希望让参与者熟悉临床环境,在整个学习过程中获得额外的知识和技能。研讨会的目的是提高参与者对基本临床技术的舒适度,如采血和外周静脉导管,已经完成。研究的结果使我们能够调整课程和测试程序,以更好地满足参与者的需求。
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引用次数: 0
Comparison of Multinational Medical School Students Experiences in the Face of the COVID-19 Pandemic: A Qualitative Analysis 跨国医学院学生面对新冠肺炎疫情的经历比较:定性分析
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1792
Alexandra C. Skoczek, Patrick W. Ruane, Cassidy Onley, Torhiana Haydel, Maria Valeria Ortega, H. Dean Sutphin, Alexis M. Stoner
Background: In the midst of the COVID-19 pandemic, countries, and governments around the world have implemented different measures and guidelines for the containment and mitigation of the COVID-19 virus. In addition to implemented policies and initiatives, social media and personal beliefs have affected medical students’ social, emotional, financial, and academic stability and success both domestically and internationally. The objective of this study was to assess medical student's perspectives, attitudes, and insight in the face of the COVID-19 pandemic and determine if differences exist between countries. Methods: This qualitative study, recruited students enrolled in the Global Seminar for Health and Environment elective course in their respective medical schools to complete a weekly, non-graded journaling assignment for 6 weeks. To measure outcomes, open-ended questions within the assignment asked students across four different countries questions regarding the COVID-19 pandemic including personal beliefs and knowledge, policies and initiatives within their country, global policies and initiatives, and social media presentations. Thematic analysis was then completed using the QCoder package in R Studio. Results: Both internationally and in the US, COVID-19 has had a large impact on medical students; however, their perspectives are distinct in personal beliefs, policies, and social media. International medical students believed that their country's COVID-19 response contained more restrictions than the global response, with the theme being expressed in 11 of 67 responses (16.4%) compared to 1 of 75 responses (1.3%) of US responses. This was enforced by the US medical students' views that the US had fewer COVID-19 restrictions. US medical students had a higher number of responses with the theme “more restrictions internationally” which was present in 21 of 75 responses (28%). US medical students were more likely to express a decrease in the number of academic opportunities and academic performance. The theme “decrease in academic opportunities and performance” was present in 15 of 75 US responses (20%) compared to 9 of 67 international responses (13.4%). A US response containing this theme was as follows: “I have had to adjust to a new way of doing school, mainly online, as well as coming to terms with the fact that I am not getting to experience many of the social aspects of medical school that I was looking forward to.” The US responses showed less of a mental health impact and expressed stronger negative views on how COVID-19 was handled with 40 of 75 US responses (53.3%) reporting the theme “need better initiatives and policies. Conclusion: The COVID-19 pandemic continues to affect medical students globally. The current study was limited by responses and student participation each week. Future studies aimed at analyzing specific COVID-19 policies around the world and the extent of the pandemic’s impact on mental health may provide greater i
背景:在2019冠状病毒病大流行期间,世界各国和政府实施了不同的措施和指导方针来遏制和缓解COVID-19病毒。除了实施的政策和举措外,社交媒体和个人信仰还影响了医学生在国内和国际上的社会、情感、经济和学术稳定和成功。本研究的目的是评估医学生面对COVID-19大流行的观点、态度和洞察力,并确定国家之间是否存在差异。方法:这项定性研究招募了在各自医学院参加全球健康与环境研讨会选修课程的学生,让他们每周完成一项为期6周的非评分日志作业。为了衡量结果,作业中的开放式问题向来自四个不同国家的学生提问有关COVID-19大流行的问题,包括个人信仰和知识、本国的政策和举措、全球政策和举措以及社交媒体演示。然后使用R Studio中的QCoder包完成主题分析。结果:无论是在国际上还是在美国,COVID-19都对医学生产生了很大的影响;然而,他们在个人信仰、政策和社交媒体上的观点却截然不同。国际医学生认为,他们国家的COVID-19应对措施比全球应对措施包含更多限制,67份答复中有11份(16.4%)表达了这一主题,而美国的75份答复中有1份(1.3%)表达了这一主题。这是因为美国医学生认为美国对新冠病毒的限制更少。美国医科学生以“国际上更多的限制”为主题的答复较多,在75份答复中有21份(28%)。美国医学生更有可能表达学术机会和学业成绩的减少。75个美国受访者中有15个(20%)提出了“学习机会和成绩下降”的主题,而67个国际受访者中有9个(13.4%)提出了这一主题。一个美国人的回答包含了这样一个主题:“我不得不适应一种新的学习方式,主要是在线学习,同时也不得不接受这样一个事实,即我无法体验到我所期待的医学院的许多社交方面。”美国的回答对心理健康的影响较小,对如何应对COVID-19表达了更强烈的负面看法,75个美国回答中有40个(53.3%)报告了“需要更好的举措和政策”的主题。结论:新冠肺炎疫情持续影响全球医学生。目前的研究受到每周反馈和学生参与的限制。未来的研究旨在分析世界各地的具体COVID-19政策以及大流行对心理健康的影响程度,这可能会让我们更深入地了解医学生在过去一年中受到挑战的信仰、态度和福祉。无论如何,必须承认,医学院的经历已经改变了国际和美国医学生,不仅在学业上,而且在精神上、社会上和经济上影响了他们。
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引用次数: 2
The Effect of Oral Magnesium Supplement on Pre-eclampsia and Perinatal Outcomes in Pregnancy: A Meta-Analysis of Randomized Controlled Trials 口服镁补充剂对妊娠子痫前期和围产期结局的影响:一项随机对照试验的荟萃分析
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1808
A. Khaity, K. Albakri, Y. Alabdallat, Othman Saleh, Hazem. S Ghaith
Background: Magnesium is one of the most important nutritional factors that have a beneficial effect on pregnant women. Many studies evaluated the role of oral magnesium supplements as a non-pharmacological intervention for mother and neonatal protection in terms of these outcomes. There is a conflict between several clinical trials about the efficacy of oral magnesium supplements during pregnancy. Therefore, in this review, we represent class 1 evidence and address an unmet clinical need on the efficacy of different types of oral magnesium in pre-eclampsia, and prenatal outcomes in pregnant women. Method: During the preparation of this meta-analysis, we followed the PRISMA statement guidelines. A literature search of the Web of Sciences, Cochrane Central Register of Controlled Trials, and PubMed were conducted from inception until September 2022. We included randomized controlled trials (RCTs) comparing oral magnesium whether citrate, oxide, or aspartate hydrochloride with a placebo. The records of quality studies were screened and extracted. Additionally, the pre-eclampsia, preterm birth, and neonatal intensive care unit (NICU) admissions data were pooled as odds ratio (OR) in a fixed-effect model using Review Manager (v.3). Subgroup analysis was performed to investigate the efficacy of each type of oral magnesium on the outcomes. Results: Five RCTs were included in this meta-analysis with a total of 2370 patients. The overall effect did not favor either of the two groups in terms of pre-eclampsia (OR= 0.99, 95% CI, [0.72, 1.37], p = 0.9), preterm birth (OR= 0.87, 95% CI, [0.62, 1.22], p = 0.4), and NICU admissions (OR= 1.37, 95% CI, [0.84, 2.22], p = 0.2). Based on the subgroup analysis findings, the use of oral magnesium supplements whether citrate, oxide, or aspartate hydrochloride in this population did not significantly increase or decrease the incidence of pre-eclampsia, preterm birth, and NICU admissions when compared with the control group. Conclusion: Ultimately, oral magnesium supplementation whether citrate, oxide, or aspartate hydrochloride may not have a beneficial effect on maternal and fetal outcomes during pregnancy. Therefore, the current evidence is insufficient to confirm the efficacy of oral magnesium for care practice among pregnant women. Despite that, these results need to be affirmed by major RCTs using magnesium supplements which have related to neonatal and maternal outcomes.
背景:镁是对孕妇有益的最重要的营养因子之一。根据这些结果,许多研究评估了口服镁补充剂作为一种非药物干预对母亲和新生儿保护的作用。关于怀孕期间口服镁补充剂的功效,几个临床试验之间存在冲突。因此,在这篇综述中,我们代表了一级证据,并解决了不同类型口服镁对先兆子痫的疗效和孕妇产前结局的临床需求。方法:在本荟萃分析的准备过程中,我们遵循PRISMA声明指南。文献检索的Web of Sciences, Cochrane Central Register of Controlled Trials和PubMed从成立到2022年9月进行。我们纳入了比较口服镁(无论是柠檬酸盐、氧化物还是天冬氨酸盐酸盐)与安慰剂的随机对照试验。筛选和提取质量研究的记录。此外,使用Review Manager (v.3)将先兆子痫、早产和新生儿重症监护病房(NICU)入院数据汇总为固定效应模型中的优势比(OR)。采用亚组分析的方法,探讨不同类型口服镁对预后的影响。结果:本荟萃分析纳入5项随机对照试验,共2370例患者。在先兆子痫(OR= 0.99, 95% CI, [0.72, 1.37], p = 0.9)、早产(OR= 0.87, 95% CI, [0.62, 1.22], p = 0.4)和新生儿重症监护病房入院(OR= 1.37, 95% CI, [0.84, 2.22], p = 0.2)方面,总体效果对两组均不利。根据亚组分析结果,与对照组相比,在该人群中使用口服镁补充剂,无论是柠檬酸盐、氧化物还是天冬氨酸盐酸盐,都没有显著增加或减少先兆子痫、早产和新生儿重症监护室入院的发生率。结论:最终,无论是柠檬酸盐、氧化物还是天冬氨酸盐酸盐,口服镁补充剂都不会对妊娠期间的母婴结局产生有益影响。因此,目前的证据不足以证实口服镁对孕妇护理实践的有效性。尽管如此,这些结果需要通过使用镁补充剂的主要随机对照试验来证实,镁补充剂与新生儿和产妇的结局有关。
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引用次数: 0
Assessment Syrian Population Knowledge, Attitudes and Perceptions Towards Stroke: A Cross-Sectional Study from Syria 评估叙利亚人口对中风的知识、态度和看法:来自叙利亚的横断面研究
Pub Date : 2023-02-21 DOI: 10.5195/ijms.2022.1827
Yazan Khair Eldien Jabban, S. Swed, H. Bohsas, Hidar Alibrahim, Nagham Jawish, B. Sawaf, W. Hafez
Background: Based on the stroke mortality rate, Syria was ranked 98th worldwide in 2020. Approximately 80% of strokes are avoidable by managing well-known modifiable risk factors, such as diabetes, hypertension, and cardiovascular disease. Due to the high prevalence of several modifiable risk factors for stroke in Syria, it is necessary to increase Syrians' understanding of strokes and encourage people to engage in healthy practices to eradicate these risk factors. This research aimed to evaluate the knowledge, attitudes, and health-related perceptions of adult Syrians about stroke.   Methods: This cross-sectional research was conducted between 2 September and 10 October 2022 among Syrians using an online survey to measure their knowledge, attitudes, and practices regarding stroke. This questionnaire was derived from a previously published article, and the inclusion criteria for this research were all Syrian residents aged 18 or older. The questionnaire utilized for this study consisted of three major sections: socio-demographic data, knowledge of stroke, and attitudes and perceptions about stroke.   RESULTS: 53.3 % of the 1,143 research participants were female. Most respondents (94.3%) recognized the brain as the organ impacted by stroke. Hypertension was the stroke's most identifiable cause and risk factor (72.8% and 73.6%, respectively). 72.8 % of participants recognized hypertension and atherosclerosis as causes of stroke. 94.3 % of survey participants accurately identified the oranges impacted by the stroke; however, only 50.1% properly identified the warning symptoms. 61.4 % of participants utilize the Internet as a source of stroke-related information. 22.3% of individuals aged 21 to 30 had identified at least one stroke warning sign. 12.58% of individuals with a high socioeconomic position have shown a solid understanding of stroke risk factors. Females were projected to be 1.55 times more knowledgeable about stroke warning signs than men (P value<0.05). It was expected that participants who believed that stroke is avoidable would be 2.2 times more knowledgeable about stroke warning signals than those who disagreed (P value<0.05). Participants who identified more than four causes of stroke were expected to have 14.77 times more knowledge of stroke risk factors than those who did not (P value<0.05).   Conclusion: Our research shows that although knowledge of stroke risk factors and symptoms is moderate to good, there is still a lack of perceptions toward this disease. Hopefully, this will encourage hospitals and other medical groups to continue their awareness-raising campaigns about the dangers of this illness. Stroke prevention and community response may be greatly enhanced by raising public consciousness of the condition and fostering individual agency in coping with it.
背景:根据中风死亡率,叙利亚在2020年全球排名第98位。通过控制众所周知的可改变的危险因素,如糖尿病、高血压和心血管疾病,大约80%的中风是可以避免的。由于叙利亚中风的几种可改变的危险因素非常普遍,因此有必要提高叙利亚人对中风的了解,并鼓励人们采取健康的做法,以消除这些危险因素。本研究旨在评估叙利亚成年人对中风的知识、态度和健康相关认知。方法:这项横断面研究于2022年9月2日至10月10日在叙利亚人中进行,通过在线调查来衡量他们对中风的知识、态度和做法。该问卷来源于先前发表的一篇文章,本研究的纳入标准是所有18岁或以上的叙利亚居民。本研究使用的问卷包括三个主要部分:社会人口统计数据、中风知识和对中风的态度和看法。结果:1143名研究参与者中53.3%为女性。大多数受访者(94.3%)认为大脑是受中风影响的器官。高血压是中风最明显的原因和危险因素(分别为72.8%和73.6%)。72.8%的参与者认为高血压和动脉粥样硬化是中风的原因。94.3%的调查参与者准确地识别出受中风影响的橙子;然而,只有50.1%的人正确识别了警告症状。61.4%的参与者利用互联网作为中风相关信息的来源。22.3%的21至30岁的人至少发现了一个中风警告信号。12.58%的社会经济地位较高的个体对卒中危险因素有扎实的了解。女性对中风警告信号的了解程度是男性的1.55倍(P值<0.05)。认为卒中是可以避免的受试者对卒中预警信号的了解程度是不认为卒中可避免的受试者的2.2倍(P值<0.05)。发现四种以上中风原因的参与者对中风危险因素的了解是没有发现的参与者的14.77倍(P值<0.05)。结论:我们的研究表明,虽然对中风危险因素和症状的认识是中等到良好的,但对这种疾病仍然缺乏认识。希望这将鼓励医院和其他医疗团体继续开展提高人们对这种疾病危险的认识的运动。通过提高公众对中风的认识和培养个人应对中风的能力,中风的预防和社区反应可能会得到极大的加强。
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International journal of medical students
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