JAACAP open最新文献

{"title":"Prophylactic Effect of N-Acetylcysteine in an Adolescent With Trichotillomania After Acetaminophen Overdose","authors":"Michael Ferguson MD, Caroline M. Mebane MS, Abhishek Reddy MD","doi":"10.1016/j.jaacop.2023.03.002","DOIUrl":"10.1016/j.jaacop.2023.03.002","url":null,"abstract":"","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 1","pages":"Pages 74-75"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47382758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis Use Is Associated With Depression Severity and Suicidality in the National Comorbidity Survey−Adolescent Supplement","authors":"Jesse D. Hinckley MD, PhD ,&nbsp;Susan K. Mikulich-Gilbertson PhD ,&nbsp;Jian-Ping He MS ,&nbsp;Devika Bhatia MD ,&nbsp;Jarrod M. Ellingson PhD ,&nbsp;Brian Nguyenkhoa Vu MD ,&nbsp;Kathleen Ries Merikangas PhD ,&nbsp;Joseph T. Sakai MD","doi":"10.1016/j.jaacop.2023.02.002","DOIUrl":"10.1016/j.jaacop.2023.02.002","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the association of cannabis use with major depression and suicidal behavior in adolescence.</p></div><div><h3>Method</h3><p>Data are from the National Comorbidity Survey−Adolescent Supplement (N = 10,123), a nationally representative survey of adolescents aged 13 to 18 years. Weighted logistic regression and ordinal regression analyses of major depression and suicidal behavior outcomes were conducted on cannabis variables, incorporating sociodemographic characteristics.</p></div><div><h3>Results</h3><p>Adolescents with lifetime cannabis use have 2.07 times higher odds of mild/moderate (adjusted odds ratio [aOR]; 95% CI = 1.69, 2.53) and 3.32 times higher odds of severe major depressive disorder (MDD; aOR; 95% CI = 2.31, 4.75). Cannabis use (aOR 6.90, 95% CI = 4.67, 10.19), mild/moderate MDD (aOR 4.10, 95% CI = 2.82, 5.98), and severe MDD (aOR 13.97, 95% CI = 7.59, 25.70) were associated with higher odds of suicide attempt. Past 12-month cannabis use (aOR 3.70, 95% CI = 2.16, 6.32), mild/moderate major depressive episodes (MDE) (aOR 7.85, 95% CI = 3.59, 17.17), and severe MDE (aOR 36.36, 95% CI = 13.68, 96.64) were associated with higher odds of suicide attempt. The frequency of past 12-month cannabis use was associated with higher odds of suicide attempt and with MDE severity, with higher odds among individuals who use cannabis 3 or more days than among individuals who use cannabis less frequently, suggesting a dose effect. Among cannabis users, older age of onset of cannabis use was associated with lower odds of suicidal behaviors.</p></div><div><h3>Conclusion</h3><p>Cannabis use is associated with higher odds of depression and depression severity in adolescence. Furthermore, depression and cannabis use are independently associated with higher odds of suicide attempt.</p></div><div><h3>Diversity &amp; Inclusion Statement</h3><p>We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. We actively worked to promote sex and gender balance in our author group. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group.</p></div>","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 1","pages":"Pages 24-35"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10318743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Children With Attention-Deficit/Hyperactivity Disorder Symptoms Become Socially Isolated? Longitudinal Within-Person Associations in a Nationally Representative Cohort","authors":"Katherine N. Thompson MSc ,&nbsp;Jessica C. Agnew-Blais PhD ,&nbsp;Andrea G. Allegrini PhD ,&nbsp;Bridget T. Bryan MSc ,&nbsp;Andrea Danese MD, PhD ,&nbsp;Candice L. Odgers PhD ,&nbsp;Timothy Matthews PhD ,&nbsp;Louise Arseneault PhD","doi":"10.1016/j.jaacop.2023.02.001","DOIUrl":"10.1016/j.jaacop.2023.02.001","url":null,"abstract":"<div><h3>Objective</h3><p>This study examined longitudinal associations between attention-deficit/hyperactivity disorder (ADHD) symptoms and social isolation across childhood. The study tested the direction of this association across time, while accounting for preexisting characteristics, and assessed whether this association varied by ADHD presentation, informant, sex, and socioeconomic status.</p></div><div><h3>Method</h3><p>Participants included 2,232 children from the Environmental Risk (E-Risk) Longitudinal Twin Study. ADHD symptoms and social isolation were measured at ages 5, 7, 10, and 12. Random-intercept cross-lagged panel models were used to assess the directionality of the association across childhood.</p></div><div><h3>Results</h3><p>Children with increased ADHD symptoms were consistently at increased risk of becoming socially isolated later in childhood, over and above stable characteristics (β = .05-.08). These longitudinal associations were not bidirectional; isolated children were not at risk of worsening ADHD symptoms later on. Children with hyperactive ADHD presentation were more likely to become isolated, compared with inattentive presentation. This was evident in the school setting, as observed by teachers, but not by mothers at home.</p></div><div><h3>Conclusion</h3><p>The study findings highlight the importance of enhancing peer social support and inclusion for children with ADHD, particularly in school settings. This study adds explanatory value beyond traditional longitudinal methods, as the results represent how individual children change over time, relative to their own preexisting characteristics.</p></div><div><h3>Diversity &amp; Inclusion Statement</h3><p>We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. We actively worked to promote sex and gender balance in our author group. The author list of this paper includes contributors from the location and/or community where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work.</p></div>","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 1","pages":"Pages 12-23"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10377013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}