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Systematic Review: Child Psychiatry Access Program Outcomes 系统评价:儿童精神病学准入项目结果
Pub Date : 2023-11-01 DOI: 10.1016/j.jaacop.2023.07.003
Chuan-Mei Lee MD, MA , Juliet Yonek PhD, MPH , Brendon Lin BA , Matthew Bechelli MD , Petra Steinbuchel MD , Lisa Fortuna MD, MPH, MDiv , Christina Mangurian MD, MAS

Objective

There has been an increase in Child Psychiatry Access Programs (CPAP) across the United States to address the national child and adolescent psychiatry workforce shortage by supporting pediatric primary care providers (PCPs) in providing mental health services. The objective of this systematic review is to synthesize the expanding literature on CPAPs.

Method

A systematic literature search was conducted in PubMed, PsycInfo, Embase, and Web of Science databases to identify articles published from database inception to April 6, 2022, to identify CPAPs, defined as programs with mental health specialists providing rapid remote mental health consultation services to pediatric PCPs. Study outcomes included program adoption, provider experience, patient and caregiver experience, program cost, and patient mental health.

Results

None of the 33 included studies were randomized controlled trials. Most of the studies (n = 30) focused on program adoption and provider experience (n = 18). Few studies examined patient and caregiver experience (n = 2), program cost (n = 4), or patient mental health (n = 4) outcomes. CPAPs showed year-over-year growth in adoption and were generally well-received by providers and caregivers. Health care provision costs were quite varied. No articles reported on changes in patient mental health according to validated measures. Heterogeneity in the methodological quality, study design, and outcomes used to evaluate CPAPs hindered comparison among programs.

Conclusion

Rigorous research on the impact of CPAPs is lacking. Findings show high provider satisfaction with CPAPs, yet few studies examine patient-level mental health outcomes. CPAPs and funding agencies should consider prioritizing and investing in research to build the evidence base for CPAPs.

Diversity & Inclusion Statement

One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science.

Clinical trial registration information

Child Psychiatry Access Programs: A Systematic Review; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020146410; CRD42020146410

目的通过支持儿科初级保健提供者(pcp)提供心理健康服务,美国各地的儿童精神病学准入计划(CPAP)有所增加,以解决全国儿童和青少年精神病学劳动力短缺的问题。本系统综述的目的是综合有关cpap的不断扩大的文献。方法在PubMed、PsycInfo、Embase和Web of Science数据库中进行系统的文献检索,以确定从数据库建立到2022年4月6日发表的文章,以确定cpap,定义为由心理健康专家为儿科pcp提供快速远程心理健康咨询服务的项目。研究结果包括项目采用率、提供者经验、患者和护理人员经验、项目成本和患者心理健康。结果纳入的33项研究均为随机对照试验。大多数研究(n = 30)关注于项目采用和提供者经验(n = 18)。很少有研究考察患者和护理人员的经历(n = 2)、项目成本(n = 4)或患者心理健康(n = 4)结果。cpap的采用呈逐年增长趋势,并且普遍受到医疗服务提供者和护理人员的欢迎。提供保健的费用差别很大。根据有效的措施,没有文章报道患者心理健康的变化。用于评估cpap的方法学质量、研究设计和结果的异质性阻碍了项目间的比较。结论缺乏对cpap影响的严谨研究。研究结果显示,提供者对cpap的满意度很高,但很少有研究检查患者层面的心理健康结果。cpap和资助机构应该考虑优先考虑和投资研究,以建立cpap的证据基础。多样性,包含声明本文的一位或多位作者自认为是科学中一个或多个历史上未被充分代表的种族和/或族裔群体的成员。我们积极努力促进在我们的作者群体中纳入历史上代表性不足的种族和/或民族群体。本文的一位或多位作者自认为是科学界一个或多个历史上未被充分代表的性和/或性别群体的成员。儿童精神病学准入项目:系统评价https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020146410;CRD42020146410
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引用次数: 0
Neurodevelopmental Profiles of 4-Year-Olds in the Navajo Birth Cohort Study 纳瓦霍出生队列研究中4岁儿童的神经发育特征
Pub Date : 2023-11-01 DOI: 10.1016/j.jaacop.2023.06.003
Brandon J. Rennie PhD , Somer Bishop PhD , Bennett L. Leventhal MD , Shuting Zheng PhD , Ellen F. Geib PhD , Young Shin Kim MD, MS, MPH, PhD , Courtney Burnette PhD , Emma Salzman PsyD , Sara S. Nozadi PhD , Hosanna Kim MD , Whitney Ence PhD, BCBA-D , Mina Park PhD , Sheila Ghods MPH , Maria L. Welch BA , Debra MacKenzie PhD , Johnnye Lewis PhD, MA

Objective

Native American children disproportionally face many risk factors for poor developmental outcomes, including poverty, environmental toxicant exposure, and limited medical and intervention services. To understand these risks, comprehensive documentation of developmental and behavioral phenotypes is needed. In this descriptive study, the neurodevelopment of young Diné (Navajo) children was assessed using standardized assessment instruments in combination with expert clinician judgment.

Method

As part of an ongoing, population-based, prospective birth cohort study, comprehensive neurodevelopmental assessments were conducted of 138 Diné children 3 to 5 years old residing on or near the Navajo Nation. Standardized parent reports, psychiatric examinations, and direct assessments of children’s language, cognitive, adaptive, and social-emotional development, as well as best estimate clinical diagnoses were obtained.

Results

DSM-5 criteria for a neurodevelopmental disorder diagnosis were met by 49% of the sample. Language and speech sound disorders were most common, although autism spectrum disorder was also increased compared with the general population. Though language performance was low among all groups of children with and without neurodevelopmental disorders, children meeting criteria for certain neurodevelopmental disorders showed significantly lower performance on all language measures compared with children not meeting these criteria. Social-emotional, behavioral, and nonverbal cognitive ability were in the average range overall.

Conclusion

Diné children in this study were found to have a high percentage of clinically significant developmental delays. Overall, children presented with a pervasive pattern of depressed language performance across measures, irrespective of diagnosis (or no diagnosis), while other domains of functioning were similar to normative samples. Findings support the need to identify appropriate intervention and educational efforts for affected youth, while also exploring the causes of the specific developmental delays. However, longitudinal studies are necessary to establish best practices for identifying delays and delineating resilience factors to optimize development of Diné children.

目的美国儿童不成比例地面临许多不良发育结果的风险因素,包括贫困、环境有毒物质暴露以及有限的医疗和干预服务。为了了解这些风险,需要对发育和行为表型进行全面的记录。在这项描述性研究中,使用标准化的评估工具结合专家临床医生的判断来评估年轻din(纳瓦霍)儿童的神经发育。方法作为一项正在进行的、以人群为基础的前瞻性出生队列研究的一部分,对居住在纳瓦霍族或其附近的138名3至5岁的din儿童进行了全面的神经发育评估。标准化的家长报告、精神病学检查、儿童语言、认知、适应性和社会情感发展的直接评估,以及最佳估计临床诊断。结果49%的样本符合dsm -5神经发育障碍诊断标准。语言和语音障碍是最常见的,尽管自闭症谱系障碍与普通人群相比也有所增加。虽然在所有有或没有神经发育障碍的儿童中,语言表现都很低,但与不符合这些标准的儿童相比,符合某些神经发育障碍标准的儿童在所有语言测试中的表现都明显较低。社交情绪、行为和非语言认知能力总体上处于平均水平。结论本研究中所有儿童均有较高比例的临床显著发育迟缓。总体而言,无论诊断(或未诊断)如何,儿童在所有测量中都表现出普遍的抑郁语言表现模式,而其他功能领域与规范样本相似。研究结果表明,需要为受影响的青少年确定适当的干预措施和教育努力,同时也要探索具体发育迟缓的原因。然而,纵向研究是必要的,以建立最佳做法,以确定延迟和描述弹性因素,以优化dinnous儿童的发展。
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引用次数: 1
Structure of Psychopathology in Romanian Preschool-Aged Children in an Epidemiological and a High-Risk Sample 罗马尼亚学龄前儿童的流行病学和高危样本的心理病理学结构
Pub Date : 2023-11-01 DOI: 10.1016/j.jaacop.2023.06.004
Katherine L. Guyon-Harris PhD , André Plamondon PhD , Kathryn L. Humphreys PhD, EdM , Mark Wade PhD , Mary Margaret Gleason MD , Florin Tibu PhD , Charles A. Nelson PhD , Nathan A. Fox PhD , Charles H. Zeanah MD

Objective

Research on bifactor models of psychopathology in early childhood is limited to community samples with little longitudinal follow-up. We examined general and specific forms of psychopathology within 2 independent samples of preschool-aged Romanian children. Within a sample with children exposed to psychosocial deprivation, we also examined antecedents and longitudinal outcomes of the general factor.

Method

One sample consisted of 350 Romanian children (mean age = 39.7 months, SD = 10.9) from an epidemiological study; the second sample consisted of 170 Romanian children (mean age = 55.6 months, SD = 1.9) exposed to severe early-life deprivation, as well as community comparison children, with longitudinal follow-up at 8 and 12 years. Psychopathology symptoms were assessed through caregiver-reported structured clinical interviews.

Results

An SI-1 bifactor model of psychopathology was supported in both samples and included specific factors for externalizing, internalizing, and disturbed relatedness symptoms. In the second sample, longer duration of psychosocial deprivation and lower-quality caregiving were associated with higher scores on the general and all specific factors. Higher scores on the general factor were associated with later cognitive function, competence, and psychopathology symptoms. Considering all factors together, only the general factor explained variance in later childhood outcomes and was slightly stronger compared to a total symptom count for some, but not all, outcomes.

Conclusion

General psychopathology in early childhood explains meaningful variance in child outcomes across multiple domains of functioning in later childhood. However, important questions remain regarding its clinical utility and usefulness, given complex measurement and limited explanatory power beyond the more accessible approach of a total symptom count.

Clinical trial registration information

The Bucharest Early Intervention Project; https://clinicaltrials.gov/; NCT00747396.

目的对儿童早期精神病理双因素模型的研究仅限于社区样本,且缺乏纵向随访。我们在罗马尼亚学龄前儿童的2个独立样本中检查了一般和特定形式的精神病理学。在一个暴露于心理社会剥夺的儿童样本中,我们还检查了一般因素的前因和纵向结果。方法样本为来自流行病学研究的350名罗马尼亚儿童(平均年龄= 39.7个月,SD = 10.9);第二个样本包括170名早期生活严重剥夺的罗马尼亚儿童(平均年龄= 55.6个月,SD = 1.9),以及社区比较儿童,在8岁和12岁时进行纵向随访。通过护理人员报告的结构化临床访谈评估精神病理症状。结果两组样本均支持SI-1精神病理学双因素模型,该模型包含外化、内化和干扰相关症状的特定因素。在第二个样本中,较长的社会心理剥夺持续时间和较低质量的护理与一般和所有特定因素的较高得分相关。一般因素得分越高,其认知功能、能力和精神病理症状越晚。综合考虑所有因素,只有一般因素解释了儿童后期结果的差异,并且与某些(但不是全部)结果的总症状数相比略强。结论儿童早期的一般精神病理学解释了儿童后期在多个功能领域的结果有意义的差异。然而,由于复杂的测量和有限的解释力超出了更容易获得的总症状计数方法,关于其临床效用和有用性的重要问题仍然存在。临床试验注册信息布加勒斯特早期干预项目;https://clinicaltrials.gov/;NCT00747396。
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引用次数: 0
Peer Review in JAACAP Open: Promoting Integrity While Advancing Open Science JAACAP开放的同行评议:在推进开放科学的同时促进诚信
Pub Date : 2023-11-01 DOI: 10.1016/j.jaacop.2023.09.003
Robert R. Althoff MD, PhD (Associate Editor), Manpreet K. Singh MD, MS (Editor), Kara S. Bagot MD, Daniel P. Dickstein MD, FAAP, Stacy S. Drury MD, PhD, FAPA, Robert L. Findling MD, MBA (Deputy Editors), Mary K. Billingsley ELS (Managing Editor)
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引用次数: 0
Scope 范围
Pub Date : 2023-11-01 DOI: 10.1016/S2949-7329(23)00038-8
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引用次数: 0
Treatment and Outcomes Among North Carolina Medicaid-Insured Youth With Depression 北卡罗来纳州医疗保险青年抑郁症患者的治疗和结果
Pub Date : 2023-11-01 DOI: 10.1016/j.jaacop.2023.06.002
Naomi O. Davis PhD , Kelley A. Jones PhD , Alexis French PhD , Melissa A. Greiner MS , Chris Ricard Lea MD , Courtney L. McMickens MD, MPH, MHS , Nicole Heilbron PhD , Gary R. Maslow MD, MPH

Objective

Youth depression is increasing and is associated with adverse concurrent and long-term outcomes. Understanding receipt of depression treatment and outcomes is critical for population-level efforts to address youth depression. This study aimed to understand treatment patterns and their association with depression-related outcomes.

Method

North Carolina Medicaid claims were used to conduct a retrospective cohort study of treatment and depression-related outcomes in pediatric Medicaid beneficiaries. The sample included 34,623 youth ages 5 to 21 years with an incident depression diagnosis. Psychotherapy and antidepressant medication were assessed for 6 months following diagnosis. Depression-related outcomes including suicidal or self-harming behaviors, emergency department use, and psychiatric hospitalization were analyzed using Cox proportional hazards models to calculate hazard ratios.

Results

Among youth with depression, 86% received treatment (39% psychotherapy, 16% medication, 31% combined), but few youth received guideline-recommended treatment duration. At 6 and 18 months, youth who received combined treatment had higher risk of adverse outcomes compared with the other groups. The untreated group had lower risk of outcomes other than all-cause emergency department visits. Single-session psychotherapy and inconsistent medication fills were also associated with poor outcomes; however, more psychotherapy sessions were associated with lower risk of all-cause emergency department visits.

Conclusion

These data show that the majority of youth who received depression treatment had suboptimal adherence to recommended guidelines. Youth who received combined treatment (both medication and therapy) had more adverse depression outcomes. As claims records do not include clinical data, the effect of treatment type, dose, depression severity, or a combination of these factors cannot be readily disentangled; therefore, these findings do not support a conclusion that combined treatment leads to poor outcomes. Rather, it is possible that youth with a more severe clinical profile are more likely to be prescribed combined treatment or to have poor adherence and thus worse outcomes. Understanding how to improve adherence in real-world settings is needed. Results suggest that many youth continue to struggle despite receipt of mental health care, indicating a call for enhancing existing treatment strategies. Research should aim to better understand population-level care for depression and to promote receipt of and adherence to recommended treatment duration across modalities.

Diversity & Inclusion Statement

One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or mor

目的:青少年抑郁症呈上升趋势,并伴有不良的并发和长期预后。了解抑郁症治疗的接受情况和结果对解决青少年抑郁症的全民努力至关重要。本研究旨在了解治疗模式及其与抑郁症相关结果的关系。方法采用北卡罗莱纳州医疗补助申请对儿童医疗补助受益人的治疗和抑郁相关结果进行回顾性队列研究。样本包括34,623名年龄在5至21岁之间的青少年,他们被诊断为偶发性抑郁症。诊断后6个月评估心理治疗和抗抑郁药物。使用Cox比例风险模型计算风险比,分析抑郁相关结果,包括自杀或自残行为、急诊科使用情况和精神科住院情况。结果86%的青少年抑郁症患者接受了治疗(心理治疗39%,药物治疗16%,综合治疗31%),但很少有青少年接受了指南推荐的治疗时间。在6个月和18个月时,与其他组相比,接受联合治疗的青少年出现不良后果的风险更高。与全因急诊就诊相比,未治疗组的预后风险较低。单次心理治疗和不一致的药物填充也与不良结果有关;然而,更多的心理治疗与较低的全因急诊就诊风险相关。结论:这些数据表明,大多数接受抑郁症治疗的青少年对推荐指南的依从性不佳。接受联合治疗(药物和治疗)的青少年有更多的不良抑郁结果。由于索赔记录不包括临床数据,治疗类型、剂量、抑郁严重程度或这些因素的组合的影响不能轻易解开;因此,这些发现并不支持联合治疗导致不良结果的结论。更确切地说,有更严重的临床表现的年轻人更有可能被处方联合治疗,或者依从性差,从而导致更差的结果。了解如何在现实环境中提高依从性是必要的。结果表明,尽管接受了精神卫生保健,许多年轻人仍然在挣扎,这表明需要加强现有的治疗策略。研究应旨在更好地了解人群水平的抑郁症护理,并促进接受和坚持推荐的治疗时间。多样性,包含声明本文的一位或多位作者自认为是科学中一个或多个历史上未被充分代表的种族和/或族裔群体的成员。本文的一位或多位作者自认为是科学界一个或多个历史上未被充分代表的性和/或性别群体的成员。
{"title":"Treatment and Outcomes Among North Carolina Medicaid-Insured Youth With Depression","authors":"Naomi O. Davis PhD ,&nbsp;Kelley A. Jones PhD ,&nbsp;Alexis French PhD ,&nbsp;Melissa A. Greiner MS ,&nbsp;Chris Ricard Lea MD ,&nbsp;Courtney L. McMickens MD, MPH, MHS ,&nbsp;Nicole Heilbron PhD ,&nbsp;Gary R. Maslow MD, MPH","doi":"10.1016/j.jaacop.2023.06.002","DOIUrl":"10.1016/j.jaacop.2023.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>Youth depression is increasing and is associated with adverse concurrent and long-term outcomes. Understanding receipt of depression treatment and outcomes is critical for population-level efforts to address youth depression. This study aimed to understand treatment patterns and their association with depression-related outcomes.</p></div><div><h3>Method</h3><p>North Carolina Medicaid claims were used to conduct a retrospective cohort study of treatment and depression-related outcomes in pediatric Medicaid beneficiaries. The sample included 34,623 youth ages 5 to 21 years with an incident depression diagnosis. Psychotherapy and antidepressant medication were assessed for 6 months following diagnosis. Depression-related outcomes including suicidal or self-harming behaviors, emergency department use, and psychiatric hospitalization were analyzed using Cox proportional hazards models to calculate hazard ratios.</p></div><div><h3>Results</h3><p>Among youth with depression, 86% received treatment (39% psychotherapy, 16% medication, 31% combined), but few youth received guideline-recommended treatment duration. At 6 and 18 months, youth who received combined treatment had higher risk of adverse outcomes compared with the other groups. The untreated group had lower risk of outcomes other than all-cause emergency department visits. Single-session psychotherapy and inconsistent medication fills were also associated with poor outcomes; however, more psychotherapy sessions were associated with lower risk of all-cause emergency department visits.</p></div><div><h3>Conclusion</h3><p>These data show that the majority of youth who received depression treatment had suboptimal adherence to recommended guidelines. Youth who received combined treatment (both medication and therapy) had more adverse depression outcomes. As claims records do not include clinical data, the effect of treatment type, dose, depression severity, or a combination of these factors cannot be readily disentangled; therefore, these findings do not support a conclusion that combined treatment leads to poor outcomes. Rather, it is possible that youth with a more severe clinical profile are more likely to be prescribed combined treatment or to have poor adherence and thus worse outcomes. Understanding how to improve adherence in real-world settings is needed. Results suggest that many youth continue to struggle despite receipt of mental health care, indicating a call for enhancing existing treatment strategies. Research should aim to better understand population-level care for depression and to promote receipt of and adherence to recommended treatment duration across modalities.</p></div><div><h3>Diversity &amp; Inclusion Statement</h3><p>One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or mor","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 3","pages":"Pages 196-205"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48913920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our Hopes for JAACAP Open JAACAP公开赛的希望
Pub Date : 2023-09-01 DOI: 10.1016/j.jaacop.2023.07.001
Manpreet K. Singh MD, MS (Editor), Robert R. Althoff MD, PhD (Associate Editor), Kara S. Bagot MD, Daniel P. Dickstein MD, FAAP, Stacy S. Drury MD, PhD, FAPA, Robert L. Findling MD, MBA (Deputy Editors), Mary K. Billingsley ELS (Managing Editor), Douglas K. Novins MD (JAACAP Editor-in-Chief)
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引用次数: 0
What Happens to Children’s Mental Health and Peer Relationships During Periods of Restricted and Unrestricted Social Interactions? Results From the Co-SPACE Study in Primary School-Aged Children 在受限制和不受限制的社会交往期间,儿童的心理健康和同伴关系会发生什么?小学学龄儿童Co-SPACE研究的结果
Pub Date : 2023-09-01 DOI: 10.1016/j.jaacop.2023.05.003
Carolina Guzman Holst MSc, Sinziana I. Oncioiu PhD, Cathy Creswell PhD, Lucy Bowes PhD

Objective

Children’s experiences of peer victimization and peer aggression are strongly linked to their mental health. However, we do not know how this relationship is influenced by periods of restricted and unrestricted social interactions. In this study, we investigated the following: (1) the bidirectional association between children’s peer problems and mental health; (2) individual differences in the joint development of peer victimization, peer aggression, and mental health; and (3) factors associated with joint trajectories over 13 months during the COVID-19 pandemic in the United Kingdom.

Method

Our sample consisted of 2,160 children 4 to 10 years of age for whom parents or carers/caregivers completed a baseline and at least 1 follow-up online survey between March 2020 and May 2021 as part of the COVID-19: Supporting Parents, Adolescents and Children during Epidemics (Co-SPACE) study. We used generalized linear models to examine bidirectional associations, group-based trajectory modeling to map joint trajectories, and multinomial logistic regressions to identify factors associated with trajectories.

Results

Experiencing mental health difficulties during school closures increased the risk of experiencing peer victimization, but not peer aggression on return to school. Experiencing any peer problems during school closures did not predict subsequent mental health difficulties. The majority of children followed joint trajectories of low exposure to peer problems and mental health; however 16% to 17% of our sample followed joint trajectories of high exposure to peer problems and mental health. Low family income, family conflict, parental distress, special educational needs, and lack of friendships were associated with high exposure mental health and peer problem trajectories.

Conclusion

Increasing children’s mental health support during periods of isolation may not only reduce concurrent and future mental health problems but may also prevent subsequent peer problems for both vulnerable and non-vulnerable children.

Study preregistration information

Co-SPACE (Covid-19: Supporting Parents, Adolescents and Children during Epidemics); https://osf.io/.

儿童遭受同伴伤害和同伴攻击的经历与他们的心理健康密切相关。然而,我们不知道这种关系是如何受到限制和不受限制的社会互动时期的影响的。本研究主要探讨:(1)儿童同伴问题与心理健康的双向关系;(2)同伴伤害、同伴攻击与心理健康共同发展的个体差异;(3)与英国COVID-19大流行期间13个月联合轨迹相关的因素。我们的样本包括2160名4至10岁的儿童,他们的父母或照顾者/照顾者在2020年3月至2021年5月期间完成了一项基线调查和至少1项后续在线调查,作为COVID-19:流行病期间支持父母、青少年和儿童(Co-SPACE)研究的一部分。我们使用广义线性模型来检验双向关联,使用基于群体的轨迹建模来映射联合轨迹,使用多项逻辑回归来识别与轨迹相关的因素。结果学校关闭期间的心理健康问题增加了学生返校后遭受同伴侵害的风险,但没有增加同伴攻击的风险。在学校关闭期间遇到任何同伴问题并不能预示随后的心理健康问题。大多数儿童遵循低暴露于同伴问题和心理健康的共同轨迹;然而,在我们的样本中,有16%到17%的人同时存在同伴问题和心理健康问题。家庭收入低、家庭冲突、父母痛苦、特殊教育需要和缺乏友谊与高暴露心理健康和同伴问题轨迹有关。结论在孤立期增加儿童的心理健康支持不仅可以减少当前和未来的心理健康问题,还可以预防继发的同伴问题。研究注册前信息co - space (Covid-19:在流行病期间支持父母、青少年和儿童);https://osf.io/。
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引用次数: 0
Prevalence and Characterization of Avoidant Restrictive Food Intake Disorder in a Pediatric Population 儿童人群中回避性限制性食物摄入障碍的患病率和特征
Pub Date : 2023-09-01 DOI: 10.1016/j.jaacop.2023.05.001
Michelle Sader BSc (Hons), PhD Candidate , Holly A. Harris PhD , Gordon D. Waiter PhD , Margaret C. Jackson PhD , Trudy Voortman PhD , Pauline W. Jansen PhD , Justin H.G. Williams MBBS, MSc, MD (Hons), FRANZCP

Objective

Avoidant/restrictive food intake disorder (ARFID) is a relatively new feeding and eating disorder category in DSM-5 characterized by extreme food avoidance/restriction. Much is unknown about ARFID, with limited understanding of its prevalence and comorbidities in general pediatric populations. This study aimed to classify ARFID prevalence and characteristics in children within the Generation R Study, a population-based Dutch cohort (N = 2,862).

Method

ARFID was assessed via an Index that comprised parent-reported questionnaires and researcher-assessed measures of picky eating, energy intake, diet quality, growth, and psychosocial impact, all in the absence of body/weight dissatisfaction to align with DSM-5 criteria. Parents also reported on child appetitive traits and emotional/behavioral problems (eg, anxiety, depression, attention problems).

Results

Using DSM-5–based categorization, 183 (6.4%) of 2,862 children were classified as presenting with ARFID symptoms. Compared with children not exhibiting symptoms, children classified with ARFID symptomatology expressed other avoidant eating behavior, including decreased enjoyment of food (d = −1.06, false discovery rate–corrected p [pFDR] < .001), increased satiety responsiveness (d = 1.06, pFDR < .001), and emotional undereating (d = 0.21, pFDR < .01), as well as more emotional problems, including withdrawn/depressed (d = 0.38, pFDR < .001), social problems (d = 0.34, pFDR < 0.001), attention problems (d = 0.38, pFDR < .001), anxiety (d = 0.30, pFDR < .001), obsessive/compulsive problems (d = 0.15, pFDR < .05), and autistic traits (d = 0.22; pFDR < .05). Associations did not differ by sex.

Conclusion

This is the first large-scale community-based study to characterize ARFID and to demonstrate that ARFID symptom classification is common in children aged ≤10 years. Findings suggest that appetitive, emotional, and behavioral comorbidities may underlie or reinforce the presentation of ARFID.

Diversity & Inclusion Statement

We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. Diverse cell lines and/or genomic datasets were not available. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list. The author list of this paper includes contributors from the location and/or community

目的:回避/限制性食物摄入障碍(ARFID)是DSM-5中一个相对较新的进食障碍类别,其特征是极度避免/限制食物。关于ARFID还有很多未知之处,对其在普通儿科人群中的患病率和合并症的了解有限。本研究旨在对R世代研究中儿童ARFID的患病率和特征进行分类,这是一项基于人群的荷兰队列研究(N = 2,862)。方法通过一个指数来评估fid,该指数包括父母报告的问卷和研究者评估的挑食、能量摄入、饮食质量、生长和心理社会影响的测量,所有这些都没有身体/体重不满意,以符合DSM-5标准。家长还报告了孩子的食欲特征和情绪/行为问题(如焦虑、抑郁、注意力问题)。结果采用基于dsm -5的分类,2862名儿童中有183名(6.4%)被归类为ARFID症状。与未出现症状的儿童相比,ARFID症状分类的儿童表现出其他回避性饮食行为,包括对食物的享受减少(d = - 1.06,错误发现率校正p [pFDR] <.001),增加饱腹感反应(d = 1.06, pFDR <.001),情绪不足(d = 0.21, pFDR <.01),以及更多的情绪问题,包括孤僻/抑郁(d = 0.38, pFDR <.001),社会问题(d = 0.34, pFDR <0.001),注意问题(d = 0.38, pFDR <.001),焦虑(d = 0.30, pFDR <.001),强迫/强迫问题(d = 0.15, pFDR <.05),自闭症特征(d = 0.22;pFDR & lt;. 05)。这种关联没有性别差异。结论:这是首次大规模社区研究ARFID特征,并证明ARFID症状分类在≤10岁儿童中很常见。研究结果表明食欲、情绪和行为合并症可能是ARFID的基础或加强。多样性,纳入声明我们努力在招募人类参与者时确保性别和性别平衡。我们努力确保招募人类参与者的种族、民族和/或其他类型的多样性。没有不同的细胞系和/或基因组数据集。在引用与本工作科学相关的参考文献的同时,我们还积极努力促进在我们的参考文献列表中纳入历史上代表性不足的种族和/或民族群体。本文的作者列表包括来自研究开展地和/或社区的贡献者,他们参与了数据收集、设计、分析和/或解释工作。我们积极地在我们的作者群体中促进性别和性别平衡。本文的一位或多位作者自认为是科学界一个或多个历史上未被充分代表的性和/或性别群体的成员。
{"title":"Prevalence and Characterization of Avoidant Restrictive Food Intake Disorder in a Pediatric Population","authors":"Michelle Sader BSc (Hons), PhD Candidate ,&nbsp;Holly A. Harris PhD ,&nbsp;Gordon D. Waiter PhD ,&nbsp;Margaret C. Jackson PhD ,&nbsp;Trudy Voortman PhD ,&nbsp;Pauline W. Jansen PhD ,&nbsp;Justin H.G. Williams MBBS, MSc, MD (Hons), FRANZCP","doi":"10.1016/j.jaacop.2023.05.001","DOIUrl":"10.1016/j.jaacop.2023.05.001","url":null,"abstract":"<div><h3>Objective</h3><p>Avoidant/restrictive food intake disorder (ARFID) is a relatively new feeding and eating disorder category in <em>DSM-5</em> characterized by extreme food avoidance/restriction. Much is unknown about ARFID, with limited understanding of its prevalence and comorbidities in general pediatric populations. This study aimed to classify ARFID prevalence and characteristics in children within the Generation R Study, a population-based Dutch cohort (N = 2,862).</p></div><div><h3>Method</h3><p>ARFID was assessed via an Index that comprised parent-reported questionnaires and researcher-assessed measures of picky eating, energy intake, diet quality, growth, and psychosocial impact, all in the absence of body/weight dissatisfaction to align with <em>DSM-5</em> criteria. Parents also reported on child appetitive traits and emotional/behavioral problems (eg, anxiety, depression, attention problems).</p></div><div><h3>Results</h3><p>Using <em>DSM-5</em>–based categorization, 183 (6.4%) of 2,862 children were classified as presenting with ARFID symptoms. Compared with children not exhibiting symptoms, children classified with ARFID symptomatology expressed other avoidant eating behavior, including decreased enjoyment of food (<em>d</em> = −1.06, false discovery rate–corrected <em>p</em> [<em>p</em><sub>FDR</sub>] &lt; .001), increased satiety responsiveness (<em>d</em> = 1.06, <em>p</em><sub>FDR</sub> &lt; .001), and emotional undereating (<em>d</em> = 0.21, <em>p</em><sub>FDR</sub> &lt; .01), as well as more emotional problems, including withdrawn/depressed (<em>d</em> = 0.38, <em>p</em><sub>FDR</sub> &lt; .001), social problems (<em>d</em> = 0.34, <em>p</em><sub>FDR</sub> &lt; 0.001), attention problems (<em>d</em> = 0.38, <em>p</em><sub>FDR</sub> &lt; .001), anxiety (<em>d</em> = 0.30, <em>p</em><sub>FDR</sub> &lt; .001), obsessive/compulsive problems (<em>d</em> = 0.15, <em>p</em><sub>FDR</sub> &lt; .05), and autistic traits (<em>d</em> = 0.22; <em>p</em><sub>FDR</sub> &lt; .05). Associations did not differ by sex.</p></div><div><h3>Conclusion</h3><p>This is the first large-scale community-based study to characterize ARFID and to demonstrate that ARFID symptom classification is common in children aged ≤10 years. Findings suggest that appetitive, emotional, and behavioral comorbidities may underlie or reinforce the presentation of ARFID.</p></div><div><h3>Diversity &amp; Inclusion Statement</h3><p>We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. Diverse cell lines and/or genomic datasets were not available. While citing references scientifically relevant for this work, we also actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our reference list. The author list of this paper includes contributors from the location and/or community ","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 2","pages":"Pages 116-127"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42778000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Factors Associated With Medication Adherence in Youth With Bipolar Disorder 检查与双相情感障碍青少年药物依从性相关的因素
Pub Date : 2023-09-01 DOI: 10.1016/j.jaacop.2023.06.001
Mohamed Y. Elhosary MD , John A. Merranko MA , Tina R. Goldstein PhD , Danella M. Hafeman MD, PhD , Benjamin I. Goldstein MD, PhD , Mary Kay Gill MSN , Heather Hower MSW , David A. Axelson MD , Jeffrey I. Hunt MD , Shirley Yen PhD , Rasim Somer Diler MD , Neal D. Ryan MD , Martin B. Keller MD , Lauren M. Weinstock PhD , Michael Strober PhD , Boris Birmaher MD

Objective

To assess medication adherence and factors associated with poor adherence in youth with bipolar disorder followed from adolescence through young adulthood.

Method

Participants with bipolar disorder recruited through the Course and Outcome of Bipolar Youth (COBY) study were included in this study if they were prescribed psychotropic medications and had at least 3 follow-up assessments of medication adherence (N = 179, ages 12-36). Medication adherence had been evaluated for a median of 8 years using a questionnaire derived from the Coronary Artery Risk Development in Young Adults (CARDIA) study. For the longitudinal evaluation, adherence was measured as the percentage of follow-up assessments in which the participants did not endorse any of the nonadherence items included in the questionnaire. Concurrent and future predictors of poor adherence were assessed using both univariate and multivariate longitudinal analyses.

Results

Among the participants, 51% reported poor adherence in more than 50% of their follow-up assessments. Younger age, family conflicts, polypharmacy, lower functioning, greater severity of mood symptoms, and comorbid disorders were associated with poor adherence in the univariate analyses. In the multivariate analyses, comorbid attention-deficit/hyperactivity disorder was the single most influential factor associated with concurrent and future poor adherence in all age groups. Participants’ most reported reasons for poor adherence were forgetfulness (56%), negative attitudes toward medication treatment (10.5%), and disturbed daily routine (7%).

Conclusion

Poor medication adherence is a significant problem in youth with bipolar disorder, with the most influential factor being the presence of comorbid attention-deficit/hyperactivity disorder. Thus, it is important to identify and appropriately treat comorbid attention-deficit/hyperactivity disorder to improve medication adherence and prognosis of patients. Providers should also recommend tools to enhance consistent medication intake and address patients’ concerns and negative beliefs about their illness and treatment.

目的评估青少年双相情感障碍患者从青春期到青年期的药物依从性及与依从性差相关的因素。方法通过双相情感障碍青年病程与结局(COBY)研究招募的双相情感障碍患者纳入本研究,如果他们开了精神药物并至少进行了3次药物依从性随访评估(N = 179,年龄12-36岁)。使用来自年轻人冠状动脉风险发展(CARDIA)研究的问卷,对药物依从性进行了中位8年的评估。对于纵向评估,依从性被测量为随访评估中参与者不赞同问卷中任何不依从性项目的百分比。使用单变量和多变量纵向分析评估当前和未来依从性差的预测因素。结果在参与者中,51%的人报告在超过50%的随访评估中依从性差。在单变量分析中,年龄小、家庭冲突、多药、功能低下、更严重的情绪症状和合并症与依从性差有关。在多变量分析中,共病性注意缺陷/多动障碍是所有年龄组中并发和未来依从性差的最重要影响因素。参与者报告的依从性差的最主要原因是健忘(56%),对药物治疗的消极态度(10.5%)和扰乱日常生活(7%)。结论青少年双相情感障碍患者服药依从性差是一个重要问题,影响其服药依从性的最主要因素是并发注意缺陷/多动障碍。因此,识别并适当治疗合并症的注意缺陷/多动障碍对改善患者的药物依从性和预后具有重要意义。提供者还应推荐一些工具,以加强持续的药物摄入,并解决患者对其疾病和治疗的担忧和消极信念。
{"title":"Examining Factors Associated With Medication Adherence in Youth With Bipolar Disorder","authors":"Mohamed Y. Elhosary MD ,&nbsp;John A. Merranko MA ,&nbsp;Tina R. Goldstein PhD ,&nbsp;Danella M. Hafeman MD, PhD ,&nbsp;Benjamin I. Goldstein MD, PhD ,&nbsp;Mary Kay Gill MSN ,&nbsp;Heather Hower MSW ,&nbsp;David A. Axelson MD ,&nbsp;Jeffrey I. Hunt MD ,&nbsp;Shirley Yen PhD ,&nbsp;Rasim Somer Diler MD ,&nbsp;Neal D. Ryan MD ,&nbsp;Martin B. Keller MD ,&nbsp;Lauren M. Weinstock PhD ,&nbsp;Michael Strober PhD ,&nbsp;Boris Birmaher MD","doi":"10.1016/j.jaacop.2023.06.001","DOIUrl":"10.1016/j.jaacop.2023.06.001","url":null,"abstract":"<div><h3>Objective</h3><p>To assess medication adherence and factors associated with poor adherence in youth with bipolar disorder followed from adolescence through young adulthood.</p></div><div><h3>Method</h3><p>Participants with bipolar disorder recruited through the Course and Outcome of Bipolar Youth (COBY) study were included in this study if they were prescribed psychotropic medications and had at least 3 follow-up assessments of medication adherence (N = 179, ages 12-36). Medication adherence had been evaluated for a median of 8 years using a questionnaire derived from the Coronary Artery Risk Development in Young Adults (CARDIA) study. For the longitudinal evaluation, adherence was measured as the percentage of follow-up assessments in which the participants did not endorse any of the nonadherence items included in the questionnaire. Concurrent and future predictors of poor adherence were assessed using both univariate and multivariate longitudinal analyses.</p></div><div><h3>Results</h3><p>Among the participants, 51% reported poor adherence in more than 50% of their follow-up assessments. Younger age, family conflicts, polypharmacy, lower functioning, greater severity of mood symptoms, and comorbid disorders were associated with poor adherence in the univariate analyses. In the multivariate analyses, comorbid attention-deficit/hyperactivity disorder was the single most influential factor associated with concurrent and future poor adherence in all age groups. Participants’ most reported reasons for poor adherence were forgetfulness (56%), negative attitudes toward medication treatment (10.5%), and disturbed daily routine (7%).</p></div><div><h3>Conclusion</h3><p>Poor medication adherence is a significant problem in youth with bipolar disorder, with the most influential factor being the presence of comorbid attention-deficit/hyperactivity disorder. Thus, it is important to identify and appropriately treat comorbid attention-deficit/hyperactivity disorder to improve medication adherence and prognosis of patients. Providers should also recommend tools to enhance consistent medication intake and address patients’ concerns and negative beliefs about their illness and treatment.</p></div>","PeriodicalId":73525,"journal":{"name":"JAACAP open","volume":"1 2","pages":"Pages 105-115"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49211445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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