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EFFECT OF ß-HYDROXY-ß-METHYLBUTYRATE (HMB) ON MUSCLE STRENGTH IN OLDER ADULTS WITH LOW PHYSICAL FUNCTION ß-羟基-ß-甲基丁酸酯(hmb)对身体机能低下老年人肌力的影响
Pub Date : 2019-01-01 DOI: 10.14283/JARCP.2019.1
K. Kinoshita, S. Satake, Y. Matsui, S. Kawashima, H. Arai
Objectives: To evaluate the effects of β-hydroxy-β-methylbutyrate (HMB) on muscle strength, physical performance, and muscle mass without additional exercise training in older adults with low physical function. Design: Randomized, controlled trial (Open-label study). Setting: Outpatients. Participants: 34 senior outpatients with low physical function who do not exercise regularly. Intervention: 2.4 g of HMB (3.0 g of calcium β-hydroxy-β-methylbutyrate [CaHMB]) per day was given for 60 days, and subjects in the control group were asked to engage in daily activities as normal. Measurements: Weakness or low function was defined by the Asian Working Group for Sarcopenia criteria, then the participants were assigned to the HMB group or the control group. All participants underwent several evaluations such as grip strength, the timed up and go test, the 5-times chair stand test (5CS), and skeletal muscle mass index by the bioimpedance method at baseline and at the end of intervention or control period. Results: An intragroup comparison of pre- to post-treatment values showed significant improvement in grip strength and the 5CS in the HMB group (grip strength: HMB, 16.6±6.1 kg to 18.2±6.4 kg, P=.001; control, 16.5±4.3 kg to 16.7±4.7 kg, P=.729; 5CS: HMB, 11.0 [8.8-13.0] s to 10.1 [8.5-12.6] s, P=.011; control, 11.1 [8.6-13.8] s to 10.0 [8.8-11.3] s, P=.246). Two-way repeated measures analysis of variance (ANOVA) used to compare the HMB and control groups showed a significant improvement in grip strength in the HMB group compared with the control group (P=.029). Conclusion: A supplementation of HMB without additional exercise may improve muscle strength in older patients with low muscle strength.
目的:评价β-羟基-β-甲基丁酸盐(HMB)对身体机能低下的老年人在没有额外运动训练的情况下肌肉力量、体能表现和肌肉质量的影响。设计:随机对照试验(开放标签研究)。设置:门诊病人。参与者:34例身体机能低下、不经常运动的老年门诊患者。干预措施:每天给予2.4 g HMB (3.0 g β-羟基-β-甲基丁酸钙[CaHMB]),持续60天,对照组正常进行日常活动。测量:虚弱或低功能由亚洲肌少症工作组定义,然后参与者被分配到HMB组或对照组。在基线和干预期或控制期结束时,所有参与者都接受了生物阻抗法的握力、计时起跑测试、5次椅站测试(5CS)和骨骼肌质量指数等多项评估。结果:组内比较治疗前后握力和5CS值,HMB组握力:HMB, 16.6±6.1 kg ~ 18.2±6.4 kg, P=.001;对照组为16.5±4.3 kg ~ 16.7±4.7 kg, P=.729;5 cs: HMB, 11.0(8.8 - -13.0)到10.1(8.5 - -12.6)年代,P = .011;控制、11.1(8.6 - -13.8)到10.0(8.8 - -11.3)年代,P = .246)。采用双向重复测量方差分析(ANOVA)对HMB组和对照组进行比较,结果显示HMB组握力较对照组有显著改善(P= 0.029)。结论:在没有额外运动的情况下补充HMB可以改善老年低肌力患者的肌力。
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引用次数: 2
ASSESSING THE IMPACT OF A NUTRITION-FOCUSED QUALITY IMPROVEMENT PROGRAM IN CARDIOPULMONARY PATIENTS 评估以营养为重点的质量改善计划对心肺病人的影响
Pub Date : 2019-01-01 DOI: 10.14283/jarcp.2019.11
M. Costanzo, S. Kozmic, S. Sulo, F. Dabbous, B. Warren, J. Partridge, Alan S. Brown, K. Sriram
Background: Patients with cardiopulmonary diagnoses are at high risk for hospital readmissions and prolonged hospitalizations. Nutrition-focused quality improvement programs (QIPs) can improve the care of malnourished hospitalized patients. Objectives: Data collected previously was analyzed to evaluate the impact of a nutrition-focused QIP on health outcomes in patients with cardiopulmonary diseases. Design: The QIP consisted of malnutrition risk screening, prompt initiation of oral nutritional supplements (ONS), and nutrition education. Setting: A total of 4 hospitals implemented the QIP–2 teaching hospitals and 2 community hospitals. Participants: Eligible QIP participants were hospitalized patients with any diagnosis, 18 years of age or older, at risk for malnutrition at admission, and able to consume food and beverages orally. Measurements: Data collected from the QIP patients was compared to data from historical controls to assess differences in readmission rates and length of stay (LOS). Results: Patients were mainly older adults (66 ± 17.4 years) and non-obese (85%). Univariate analysis showed significant reductions in 30-day readmission rates for the QIP group when compared with the controls (13.9% for QIP vs. 26.4% for controls), with the QIP group experiencing a 55% reduction in the odds of being readmitted (OR = 0.45, p = 0.006). Similarly, a significant reduction in LOS was reported for the QIP group (5.4 ± 5.7 days for QIP vs. 6.8 ± 5.7 days for controls) corresponding to a relative risk reduction (RR) of 20% (RR = 0.80, p = 0.0085). Logistic regression adjusting for patient characteristics showed that the QIP patients were 33% less likely to be readmitted (p = 0.33), and had a 6% RR (RR = 0.94, p = 0.55) in LOS versus controls. Conclusions: Malnourished hospitalized cardiopulmonary patients participating in a nutrition-focused QIP experienced fewer readmissions and improved LOS compared to controls. These results underscore the importance of nutrition-focused interventions as a key part of treatment for cardiopulmonary patients.
背景:被诊断为心肺疾病的患者再次住院和延长住院时间的风险较高。以营养为重点的质量改善计划(QIPs)可以改善对营养不良住院患者的护理。目的:分析先前收集的数据,以评估以营养为重点的QIP对心肺疾病患者健康结局的影响。设计:QIP包括营养不良风险筛查、及时开始口服营养补充剂(ONS)和营养教育。环境:共有4家医院实施了QIP-2教学医院和2家社区医院。参与者:合格的QIP参与者为任何诊断的住院患者,18岁或以上,入院时有营养不良风险,能够口服食物和饮料。测量:将从QIP患者收集的数据与历史对照组的数据进行比较,以评估再入院率和住院时间(LOS)的差异。结果:患者以老年人(66±17.4岁)和非肥胖者(85%)为主。单因素分析显示,与对照组相比,QIP组30天再入院率显著降低(QIP组为13.9%,对照组为26.4%),QIP组再入院率降低55% (OR = 0.45, p = 0.006)。同样,QIP组的LOS显著降低(QIP组为5.4±5.7天,对照组为6.8±5.7天),相对风险降低(RR) 20% (RR = 0.80, p = 0.0085)。对患者特征进行Logistic回归调整显示,QIP患者再入院的可能性降低33% (p = 0.33),与对照组相比,LOS的RR为6% (RR = 0.94, p = 0.55)。结论:与对照组相比,参加以营养为重点的QIP的营养不良住院心肺患者的再入院率更低,LOS得到改善。这些结果强调了以营养为重点的干预措施作为心肺患者治疗的关键部分的重要性。
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引用次数: 0
PREVALENCE OF UNDER NUTRITION AND ASSOCIATED FACTORS AMONG PEOPLE OF OLD AGE IN DEBRE MARKOS TOWN, NORTHWEST ETHIOPIA, 2015 2015年埃塞俄比亚西北部德布雷马科斯镇老年人营养不良患病率及相关因素
Pub Date : 2019-01-01 DOI: 10.14283/jarcp.2019.4
Z. K. Adhana, G. Tessema, G. Getie
Background: Malnutrition is defined as a disproportion of nutrients caused by either an excess intake of nutrients or a nutritional deficit. One of the most common nutritional problems in older people (aged 60 years and over) is under nutrition. Worldwide studies revealed that the prevalence of under nutrition in people of old age is high. Objective: To assess the prevalence of under nutrition and its associated factors among old people in Debre Markos town, Northwest Ethiopia, 2015. Methods and materials: A cross sectional study design was conducted among 423 study subjects of old age in Debre Markos town from August 4 to August 30, 2015. Primary data was collected using a pre tested Mini Nutritional Assessment Short-Form (MNA-SF) screening tool and structured questionnaires by trained data collectors. The data that was collected was entered and cleaned using EpiData version 3.1 statistical software then exported to the SPSS version 20 statistical package for further data analysis. Descriptive statistics of frequency, tables and graphs were used and summary measures were calculated to determine the prevalence of under nutrition. The data was also used to describe the distribution of the independent variables among study subjects. Bivariate and multivariate logistic regression models were utilized to calculate crude and adjusted odds ratios in order to identify factors associated with under nutrition of study participants at 0.05 level of significance. Result: The prevalence of under nutrition among study participants was found to be 22.7% (95%CI 18.7-26.7). A number of independent variables have a significant association with under nutrition, including gender (females (AOR 7.95 95% CI (2.86, 22.08)), age (Oldest Old and Middle Old, (AOR=3.45 95%CI (1.44, 8.26) and (AOR=5.25, 95%CI (2.48, 11.13) respectively), marital status (widowed elderly individuals (ARO 3.29 95 % CI (1.54, 7.06)), individuals with eating difficulty (AOR 10.73 95 % CI (4.49, 25.63), individuals with vision problems (AOR 5.67 95 % CI (2.80, 11.48) and meal frequency (ARO 6.71 95 % CI (3.31, 13.63). Conclusion and recommendation: Prevalence of under nutrition among study participants was 22.7%. Gender, age, marital status, eating difficulty, visual problems and meal frequency were found to be independent determinant factors of under nutrition among study subjects. The government, family members and other stakeholders should give more attention to older individuals especially older females.
背景:营养不良的定义是由营养摄入过量或营养不足引起的营养失调。老年人(60岁及以上)最常见的营养问题之一是营养不足。世界范围内的研究表明,老年人营养不足的发生率很高。目的:了解2015年埃塞俄比亚西北部Debre Markos镇老年人营养不良患病率及其相关因素。方法与材料:采用横断面研究设计,于2015年8月4日至8月30日在Debre Markos镇对423名老年人进行研究。通过预先测试的迷你营养评估简表(MNA-SF)筛选工具和经过培训的数据收集人员的结构化问卷收集主要数据。收集到的数据使用EpiData 3.1版统计软件进行录入和清理,导出到SPSS 20版统计软件包中进行进一步的数据分析。使用频率、表格和图表的描述性统计数据,并计算汇总措施,以确定营养不良的发生率。这些数据也被用来描述自变量在研究对象之间的分布。采用双变量和多变量logistic回归模型计算粗比值比和校正比值比,在0.05显著水平上确定与研究参与者营养不良相关的因素。结果:研究参与者中营养不良的患病率为22.7% (95%CI 18.7-26.7)。与营养不良相关的自变量包括性别(女性(AOR= 7.95 95%CI(2.86, 22.08))、年龄(AOR=3.45 95%CI(1.44, 8.26)和(AOR=5.25, 95%CI(2.48, 11.13))、婚姻状况(丧偶老年个体(AOR= 3.29 95%CI(1.54, 7.06))、饮食困难个体(AOR 10.73 95%CI(4.49, 25.63))、视力问题个体(AOR 5.67 95%CI(2.80, 2.88))。11.48)和用餐频率(ARO 6.71 95% CI(3.31, 13.63)。结论和建议:研究参与者中营养不良的患病率为22.7%。性别、年龄、婚姻状况、饮食困难、视力问题和用餐频率是研究对象营养不良的独立决定因素。政府、家庭成员和其他利益相关者应该更多地关注老年人,尤其是老年女性。
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引用次数: 11
PREVALENCE AND CHARACTERISTICS ASSOCIATED WITH ALCOHOL USE AND ALCOHOL RELATED PROBLEMS IN COMMUNITY DWELLING OLDER ADULTS 在社区居住的老年人中与酒精使用和酒精相关问题相关的患病率和特征
Pub Date : 2019-01-01 DOI: 10.14283/JARCP.2019.6
Y. V. Gils, E. Franck, S. V. Alphen, E. Dierckx
Objective: This study examine the prevalence, characteristics and associated factors of alcohol use and alcohol related problems among Belgian community dwelling older adults. Design: Retrospective cross-sectional study by extensive examination survey. Setting: The participants were questioned in their homes or in community centres. Participants: Overall, 1,366 adults ≥65 years participated in this study. Method: Information about self-reported alcohol use during the past year, Health Related Quality of Life (HRQL) and alcohol related problems was gathered with respectively the AUDIT, SF36 and MAST-G. Results: Of the total sample, 84.4% reported alcohol consumption. Using the NIAAA guidelines, the overall prevalence for at risk drinking was 26.6% and for binge drinking 14.8%, both risky alcohol patterns. Logistic regression analyses were performed on the drinking sample to determine the predictors associated with at risk drinking, binge drinking and hazardous drinking. Being male, a smoker of former smoker and living alone were associated with at risk drinking. Being male, being aged 65-74 years, being a smoker, reporting polypharmacy, MCS and having recent loss experience were associated with binge drinking. More than 25% of respondents were classified as hazardous drinking (score ≥5 on MAST-G). Associated factors with hazardous drinking were being male, having a family history of alcohol problems, PCS and MCS. Conclusions: The prevalence rates for at risk alcohol patterns and alcohol related problems were higher than in previous studies. As older adults are more vulnerable to the adverse consequences of alcohol use, awareness about alcohol use should be raised among older adults, as well as amongst health care givers and researchers.
目的:本研究探讨比利时社区居住老年人酒精使用和酒精相关问题的患病率、特征和相关因素。设计:通过广泛的检查调查进行回顾性横断面研究。环境:参与者在家中或社区中心接受调查。参与者:总体而言,1,366名≥65岁的成年人参与了这项研究。方法:分别使用AUDIT、SF36和MAST-G收集近一年来自我报告的酒精使用情况、健康相关生活质量(HRQL)和酒精相关问题的信息。结果:在总样本中,84.4%的人报告饮酒。根据NIAAA指南,高危饮酒的总体患病率为26.6%,酗酒的总体患病率为14.8%,两者都是高危饮酒模式。对饮酒样本进行Logistic回归分析,以确定与高危饮酒、酗酒和危险饮酒相关的预测因素。作为男性,吸烟者或戒烟者以及独居者与饮酒风险相关。男性、年龄在65-74岁之间、吸烟、服用多种药物、MCS和最近有减肥经历与酗酒有关。超过25%的应答者被归类为危险饮酒(MAST-G评分≥5)。与危险饮酒相关的因素是男性、有酗酒家族史、PCS和MCS。结论:高危酒精模式和酒精相关问题的患病率高于以往的研究。由于老年人更容易受到酒精使用的不良后果的影响,应提高老年人以及卫生保健提供者和研究人员对酒精使用的认识。
{"title":"PREVALENCE AND CHARACTERISTICS ASSOCIATED WITH ALCOHOL USE AND ALCOHOL RELATED PROBLEMS IN COMMUNITY DWELLING OLDER ADULTS","authors":"Y. V. Gils, E. Franck, S. V. Alphen, E. Dierckx","doi":"10.14283/JARCP.2019.6","DOIUrl":"https://doi.org/10.14283/JARCP.2019.6","url":null,"abstract":"Objective: This study examine the prevalence, characteristics and associated factors of alcohol use and alcohol related problems among Belgian community dwelling older adults. Design: Retrospective cross-sectional study by extensive examination survey. Setting: The participants were questioned in their homes or in community centres. Participants: Overall, 1,366 adults ≥65 years participated in this study. Method: Information about self-reported alcohol use during the past year, Health Related Quality of Life (HRQL) and alcohol related problems was gathered with respectively the AUDIT, SF36 and MAST-G. Results: Of the total sample, 84.4% reported alcohol consumption. Using the NIAAA guidelines, the overall prevalence for at risk drinking was 26.6% and for binge drinking 14.8%, both risky alcohol patterns. Logistic regression analyses were performed on the drinking sample to determine the predictors associated with at risk drinking, binge drinking and hazardous drinking. Being male, a smoker of former smoker and living alone were associated with at risk drinking. Being male, being aged 65-74 years, being a smoker, reporting polypharmacy, MCS and having recent loss experience were associated with binge drinking. More than 25% of respondents were classified as hazardous drinking (score ≥5 on MAST-G). Associated factors with hazardous drinking were being male, having a family history of alcohol problems, PCS and MCS. Conclusions: The prevalence rates for at risk alcohol patterns and alcohol related problems were higher than in previous studies. As older adults are more vulnerable to the adverse consequences of alcohol use, awareness about alcohol use should be raised among older adults, as well as amongst health care givers and researchers.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66886494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
FACTORS ASSOCIATED WITH DIMINISHED COUGH INTENSITY IN COMMUNITY-DWELLING ELDERLY USING DAY CARE SERVICES: A PILOT STUDY 使用日托服务的社区居住老年人咳嗽强度降低相关因素:一项试点研究
Pub Date : 2019-01-01 DOI: 10.14283/jarcp.2019.10
R. Mikiya, C. Momoki, D. Habu
Purpose: We investigated factors affecting diminished cough intensity in community-dwelling elderly using day care services. Participants and Methods: A total of 61 elderly males and females aged ≥65 years who were certified to receive long-term adult day care services were enrolled in this study. Assessments included: Cough intensity (assessed using cough peak flow measurements, as well as possible determinants of cough intensity, lifestyle, and demographic characteristics), nutritional status (using the Mini Nutritional Assessment-Short Form), dietary intake (using the Dietary Variety Score), routine activity (using the Japanese version of the International Physical Activity Questionnaire), care-related factors (including day care services utilization and an oral exercise regimen) as well as age, need for long-term care, gender, sarcopenia status, the Charlson Comorbidity Index, and body mass, limb skeletal mass, and respiratory indices. Results: A reduced cough peak flow (odds ratio 4.46, 95% confidence interval: 1.08–18.43) was associated with sarcopenia and was weakly (not significantly) associated with age, gender, and the Mini Nutritional Assessment-Short Form score. Conclusion: A reduced cough peak flow was independently associated with sarcopenia and associated with age, gender, and nutritional status.
目的:研究社区居住老年人使用日托服务后咳嗽强度降低的影响因素。参与者和方法:共有61名年龄≥65岁且经认证接受长期成人日托服务的老年男性和女性被纳入本研究。评估包括:咳嗽强度(使用咳嗽峰值流量测量,以及咳嗽强度、生活方式和人口统计学特征的可能决定因素进行评估)、营养状况(使用迷你营养评估-简短表格)、饮食摄入量(使用饮食多样性评分)、日常活动(使用日文版国际体育活动问卷)、护理相关因素(包括日托服务的利用和口腔运动方案)以及年龄,长期护理需求、性别、肌肉减少症状况、Charlson合并症指数、体重、肢体骨骼质量和呼吸指数。结果:咳嗽峰值流量减少(优势比4.46,95%可信区间:1.08-18.43)与肌肉减少症相关,与年龄、性别和Mini营养评估-简短形式评分的相关性较弱(不显著)。结论:咳峰流量减少与肌肉减少症独立相关,并与年龄、性别和营养状况有关。
{"title":"FACTORS ASSOCIATED WITH DIMINISHED COUGH INTENSITY IN COMMUNITY-DWELLING ELDERLY USING DAY CARE SERVICES: A PILOT STUDY","authors":"R. Mikiya, C. Momoki, D. Habu","doi":"10.14283/jarcp.2019.10","DOIUrl":"https://doi.org/10.14283/jarcp.2019.10","url":null,"abstract":"Purpose: We investigated factors affecting diminished cough intensity in community-dwelling elderly using day care services. Participants and Methods: A total of 61 elderly males and females aged ≥65 years who were certified to receive long-term adult day care services were enrolled in this study. Assessments included: Cough intensity (assessed using cough peak flow measurements, as well as possible determinants of cough intensity, lifestyle, and demographic characteristics), nutritional status (using the Mini Nutritional Assessment-Short Form), dietary intake (using the Dietary Variety Score), routine activity (using the Japanese version of the International Physical Activity Questionnaire), care-related factors (including day care services utilization and an oral exercise regimen) as well as age, need for long-term care, gender, sarcopenia status, the Charlson Comorbidity Index, and body mass, limb skeletal mass, and respiratory indices. Results: A reduced cough peak flow (odds ratio 4.46, 95% confidence interval: 1.08–18.43) was associated with sarcopenia and was weakly (not significantly) associated with age, gender, and the Mini Nutritional Assessment-Short Form score. Conclusion: A reduced cough peak flow was independently associated with sarcopenia and associated with age, gender, and nutritional status.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66885908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EVALUATION OF INPATIENTS NUTRITIONAL STATUS AND PROGNOSTIC INVOLVEMENT 住院患者营养状况及预后评估
Pub Date : 2019-01-01 DOI: 10.14283/jarcp.2019.3
J. Ares Blanco, L. Moreno Díaz, E. Fernández-Fernández, A. López-Alba
Background: There is an association between malnutrition and mortality. However, it is unclear if this association is truly independent of confounding factors. Objectives: The objective of this study is to evaluate nutritional status, defined according to the three categories defined in the Nutritional Screening Tool “Mini Nutritional Assessment”, and to investigate its prognostic involvement. Design, Setting and Participants: Single cohort retrospective observational study in hospitalized patients between December 2013 and January 2014, who were placed under observation until September 2015 (21 months) (n=144). Nutritional status was determined by MNA short form at the beginning of the study, as well as clinical and epidemiological data. Results: Based on categories defined by MNA SF, 59 (40.97%) were well nourished, 55 (38.19%) were at risk of malnutrition, and 30 (20.83%) patients showed malnutrition. 45 patients died during follow up (31.25%). Of them, 40% (18) were malnourished, 38% (17), at risk of malnutrition, and 22% (9), well nourished. After adjusting for confounding factors, hazard ratio (95% CI) for all-cause mortality was significantly greater in the malnourished group (3.44 (1,27-9,31: p 0,015)), comparing to the reference group (well-nourished patients). Conclusions: Nutritional status defined according to the 3 categories defined in MNA short form predicts the probability of mid-term death in hospitalized patients, after adjusting for confounding factors as age and comorbidities. These data show the importance of knowing nutritional status during hospitalization for avoiding potential complications and helping the patient to overcome them.
背景:营养不良与死亡率之间存在关联。然而,尚不清楚这种关联是否真正独立于混杂因素。目的:本研究的目的是根据营养筛查工具“迷你营养评估”中定义的三类来评估营养状况,并探讨其与预后的关系。设计、环境和参与者:2013年12月至2014年1月住院患者的单队列回顾性观察研究,这些患者被观察到2015年9月(21个月)(n=144)。在研究开始时,通过MNA简表以及临床和流行病学数据确定营养状况。结果:根据MNA SF定义的分类,营养良好59例(40.97%),营养不良风险55例(38.19%),营养不良30例(20.83%)。随访期间死亡45例(31.25%)。其中,40%(18人)营养不良,38%(17人)有营养不良风险,22%(9人)营养良好。在调整混杂因素后,与参照组(营养良好的患者)相比,营养不良组全因死亡率的危险比(95% CI)显著更高(3.44 (1,27-9,31:p 0,015))。结论:根据MNA简写中定义的3个类别定义的营养状况,在调整了年龄和合并症等混杂因素后,可以预测住院患者中期死亡的概率。这些数据表明了解住院期间的营养状况对于避免潜在并发症和帮助患者克服它们的重要性。
{"title":"EVALUATION OF INPATIENTS NUTRITIONAL STATUS AND PROGNOSTIC INVOLVEMENT","authors":"J. Ares Blanco, L. Moreno Díaz, E. Fernández-Fernández, A. López-Alba","doi":"10.14283/jarcp.2019.3","DOIUrl":"https://doi.org/10.14283/jarcp.2019.3","url":null,"abstract":"Background: There is an association between malnutrition and mortality. However, it is unclear if this association is truly independent of confounding factors. Objectives: The objective of this study is to evaluate nutritional status, defined according to the three categories defined in the Nutritional Screening Tool “Mini Nutritional Assessment”, and to investigate its prognostic involvement. Design, Setting and Participants: Single cohort retrospective observational study in hospitalized patients between December 2013 and January 2014, who were placed under observation until September 2015 (21 months) (n=144). Nutritional status was determined by MNA short form at the beginning of the study, as well as clinical and epidemiological data. Results: Based on categories defined by MNA SF, 59 (40.97%) were well nourished, 55 (38.19%) were at risk of malnutrition, and 30 (20.83%) patients showed malnutrition. 45 patients died during follow up (31.25%). Of them, 40% (18) were malnourished, 38% (17), at risk of malnutrition, and 22% (9), well nourished. After adjusting for confounding factors, hazard ratio (95% CI) for all-cause mortality was significantly greater in the malnourished group (3.44 (1,27-9,31: p 0,015)), comparing to the reference group (well-nourished patients). Conclusions: Nutritional status defined according to the 3 categories defined in MNA short form predicts the probability of mid-term death in hospitalized patients, after adjusting for confounding factors as age and comorbidities. These data show the importance of knowing nutritional status during hospitalization for avoiding potential complications and helping the patient to overcome them.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66886437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PREVALENCE AND PROGNOSTIC VALUE OF GERIATRIC SYNDROMES IN ELDERLY PATIENTS IN INTERMEDIATE GERIATRIC REHABILITATION UNITS 老年康复中心老年患者老年综合征的患病率及预后价值
Pub Date : 2019-01-01 DOI: 10.14283/jarcp.2019.7
M. Serra-Prat, E. Martinez-Suarez, R. Cristófol Allue, S. Santaeugènia, M. Roque, A. Salvá
Background: The prevalence and prognostic value of geriatric syndromes in geriatric rehabilitation units is poorly understood. Objective: To determine the prevalence of geriatric syndromes in intermediate geriatric rehabilitation units and evaluate associations with outcomes and death during admission. Methods: Observational, longitudinal study of patients admitted to 10 intermediate geriatric rehabilitation units in 2015. Admission-to-discharge data were collected retrospectively from a shared minimum data set (CMBD-RSS). The geriatric syndromes considered were dementia, depression, immobility, urinary incontinence, faecal incontinence, instability, insomnia, acute confusional state, terminal illness and pressure ulcers. The main outcome measures were functional status on admission (assessed using the Resource Utilization Group Activities of Daily Living Scale), functional improvement between admission and discharge, length of stay and death during admission. Results: We analysed 5619 patients (mean age 80.2 years; 57.1% women). The mean number of syndromes was 2.3. The most prevalent syndromes were urinary incontinence (62%), dementia (35%), faecal incontinence (35%) and immobility (26%). The presence of each geriatric syndrome increased the risk of functional impairment at discharge (except in the case of insomnia) and of death during admission (except in the case of instability syndrome). Conclusions: Geriatric syndromes are very prevalent in intermediate geriatric rehabilitation units and indicate a lower probability of functional recovery and a greater probability of death during admission.
背景:老年康复单位中老年综合征的患病率和预后价值尚不清楚。目的:确定老年综合征在老年康复中心的患病率,并评估其与住院期间预后和死亡的关系。方法:对2015年10家中级老年康复医院收治的患者进行观察性、纵向研究。入院至出院数据回顾性收集自共享最小数据集(CMBD-RSS)。考虑的老年综合征包括痴呆、抑郁、行动不便、尿失禁、大便失禁、不稳定、失眠、急性精神错乱、绝症和压疮。主要结局指标为入院时的功能状态(使用日常生活资源利用组活动量表评估)、入院和出院间的功能改善、住院时间和入院期间的死亡情况。结果:我们分析了5619例患者(平均年龄80.2岁;57.1%的女性)。平均证候数2.3个。最常见的症状是尿失禁(62%)、痴呆(35%)、大便失禁(35%)和行动不便(26%)。每一种老年综合征的出现都增加了出院时功能损伤(失眠症除外)和入院时死亡(不稳定综合征除外)的风险。结论:老年综合征在中级老年康复单位非常普遍,表明住院期间功能恢复的可能性较低,死亡的可能性较大。
{"title":"PREVALENCE AND PROGNOSTIC VALUE OF GERIATRIC SYNDROMES IN ELDERLY PATIENTS IN INTERMEDIATE GERIATRIC REHABILITATION UNITS","authors":"M. Serra-Prat, E. Martinez-Suarez, R. Cristófol Allue, S. Santaeugènia, M. Roque, A. Salvá","doi":"10.14283/jarcp.2019.7","DOIUrl":"https://doi.org/10.14283/jarcp.2019.7","url":null,"abstract":"Background: The prevalence and prognostic value of geriatric syndromes in geriatric rehabilitation units is poorly understood. Objective: To determine the prevalence of geriatric syndromes in intermediate geriatric rehabilitation units and evaluate associations with outcomes and death during admission. Methods: Observational, longitudinal study of patients admitted to 10 intermediate geriatric rehabilitation units in 2015. Admission-to-discharge data were collected retrospectively from a shared minimum data set (CMBD-RSS). The geriatric syndromes considered were dementia, depression, immobility, urinary incontinence, faecal incontinence, instability, insomnia, acute confusional state, terminal illness and pressure ulcers. The main outcome measures were functional status on admission (assessed using the Resource Utilization Group Activities of Daily Living Scale), functional improvement between admission and discharge, length of stay and death during admission. Results: We analysed 5619 patients (mean age 80.2 years; 57.1% women). The mean number of syndromes was 2.3. The most prevalent syndromes were urinary incontinence (62%), dementia (35%), faecal incontinence (35%) and immobility (26%). The presence of each geriatric syndrome increased the risk of functional impairment at discharge (except in the case of insomnia) and of death during admission (except in the case of instability syndrome). Conclusions: Geriatric syndromes are very prevalent in intermediate geriatric rehabilitation units and indicate a lower probability of functional recovery and a greater probability of death during admission.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66886567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
EFFECTS OF VITAMIN D SUPPLEMENTATION ON WELL-BEING, POSTURAL CONTROL, MUSCLE STRENGTH, BONE AND CALCITROPIC HORMONES – A RANDOMIZED DOUBLEBLIND PLACEBO CONTROLLED TRIAL 补充维生素d对健康、姿势控制、肌肉力量、骨骼和钙化激素的影响——一项随机双盲安慰剂对照试验
Pub Date : 2019-01-01 DOI: 10.14283/JARCP.2019.9
S. A. Eriksen, J. Starup-Linde, R. Hirata, K. Petersen, T. Graven‐Nielsen, P. Vestergaard
Background: Antidepressants may increase the risk of fractures through negative effects on the musculoskeletal system that could be hindered by vitamin D supplements. Objectives: To study the pleiotropic effects of daily vitamin D supplementation in depressed patients treated with citalopram (patients) and healthy controls. Design: Randomised double blind placebo controlled trial. Setting: A study of Danish women in the age 50 to 90 years. Participants: A total of 21 patients and 50 controls. Intervention: Participants received daily vitamin D supplementation (50 micrograms) or placebo in one year. Measurements: Bone Densitometry by dual-energy x-ray absorptiometry. Serum 25-hydroxyvitamin D, intact-Parathyroid Hormone, type 1 procollagen N terminal peptide, tartrate resistant acid phosphatase type 5b. Pain sensitivity measures based on pain detection thresholds by cuff algometry, temporal summation of pain, conditioned pain modulation, and cutaneous pain sensitivity by pinprick test. Degree of depression by the Major Depression Inventory. Physical performance was assessed by Timed up and go, isomeric handgrip exercise, and postural control by force plate. Results: Serum 25(OH)D levels increased in the vitamin D treated patients compared with controls at the 12 months visit (P<0.05). Conversely, intact- Parathyroid Hormone decreased among the patients and controls receiving vitamin D compared with placebo (P<0.05). Vitamin D improved Major Depression Inventory scores in patients and controls compared with placebo (P<0.05). In patients receiving vitamin D, handgrip strength improved (P<0.05). Conclusions: Vitamin D may improve depressive symptoms, and improve handgrip strength among patients compared to controls.
背景:抗抑郁药可能通过对肌肉骨骼系统的负面影响而增加骨折的风险,而维生素D补充剂可以阻止这种影响。目的:研究每日补充维生素D对服用西酞普兰的抑郁症患者(患者)和健康对照者的多效性作用。设计:随机双盲安慰剂对照试验。背景:一项针对50 - 90岁丹麦女性的研究。参与者:共21例患者和50例对照。干预:参与者在一年内每天服用维生素D补充剂(50微克)或安慰剂。测量方法:双能x线骨密度测定法。血清25-羟基维生素D,完整的甲状旁腺激素,1型前胶原N端肽,抗酒石酸盐酸性磷酸酶5b型。疼痛敏感性测量基于疼痛检测阈值,通过袖带测量,疼痛时间累积,条理性疼痛调节和针刺试验的皮肤疼痛敏感性。重度抑郁量表的抑郁程度。身体表现通过计时和走,异构体握力练习和姿势控制力板来评估。结果:在12个月的随访中,维生素D治疗组的血清25(OH)D水平较对照组升高(P<0.05)。相反,与安慰剂相比,服用维生素D的患者和对照组的完整甲状旁腺激素下降(P<0.05)。与安慰剂相比,维生素D改善了患者和对照组的重度抑郁量表评分(P<0.05)。服用维生素D的患者握力明显提高(P<0.05)。结论:与对照组相比,维生素D可能改善抑郁症状,并改善患者的握力。
{"title":"EFFECTS OF VITAMIN D SUPPLEMENTATION ON WELL-BEING, POSTURAL CONTROL, MUSCLE STRENGTH, BONE AND CALCITROPIC HORMONES – A RANDOMIZED DOUBLEBLIND PLACEBO CONTROLLED TRIAL","authors":"S. A. Eriksen, J. Starup-Linde, R. Hirata, K. Petersen, T. Graven‐Nielsen, P. Vestergaard","doi":"10.14283/JARCP.2019.9","DOIUrl":"https://doi.org/10.14283/JARCP.2019.9","url":null,"abstract":"Background: Antidepressants may increase the risk of fractures through negative effects on the musculoskeletal system that could be hindered by vitamin D supplements. Objectives: To study the pleiotropic effects of daily vitamin D supplementation in depressed patients treated with citalopram (patients) and healthy controls. Design: Randomised double blind placebo controlled trial. Setting: A study of Danish women in the age 50 to 90 years. Participants: A total of 21 patients and 50 controls. Intervention: Participants received daily vitamin D supplementation (50 micrograms) or placebo in one year. Measurements: Bone Densitometry by dual-energy x-ray absorptiometry. Serum 25-hydroxyvitamin D, intact-Parathyroid Hormone, type 1 procollagen N terminal peptide, tartrate resistant acid phosphatase type 5b. Pain sensitivity measures based on pain detection thresholds by cuff algometry, temporal summation of pain, conditioned pain modulation, and cutaneous pain sensitivity by pinprick test. Degree of depression by the Major Depression Inventory. Physical performance was assessed by Timed up and go, isomeric handgrip exercise, and postural control by force plate. Results: Serum 25(OH)D levels increased in the vitamin D treated patients compared with controls at the 12 months visit (P<0.05). Conversely, intact- Parathyroid Hormone decreased among the patients and controls receiving vitamin D compared with placebo (P<0.05). Vitamin D improved Major Depression Inventory scores in patients and controls compared with placebo (P<0.05). In patients receiving vitamin D, handgrip strength improved (P<0.05). Conclusions: Vitamin D may improve depressive symptoms, and improve handgrip strength among patients compared to controls.","PeriodicalId":73537,"journal":{"name":"JAR life","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66886651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DOES TAILORED NUTRITIONAL GUIDANCE ENCOURAGE OLDER CAREGIVERS TO INCREASE THEIR PROTEIN INTAKE? THE CARENUTRITION TRIAL (RCT) 量身定制的营养指导是否鼓励老年护理人员增加蛋白质摄入量?营养试验(随机对照试验)
Pub Date : 2018-01-01 DOI: 10.14283/JARCP.2018.23
S. Kunvik, R. Valve, M. Salonoja, M. Suominen
Background: Older caregivers, males especially, are vulnerable to nutritional problems. Low intake of protein is common and can affect their nutrition and health. Objectives: The aim in this RCT was to investigate the effect of tailored nutritional guidance on protein intake among caregivers aged ≥65 years with protein intake under recommendations (≤1.2 g/kgBW/d). Subgroup analysis were made with male caregivers. Design: Data from the CareNutrition randomized controlled trial (RCT). Setting: Community-dwelling caregivers from the Western part of Finland. Participants: Total of 55 caregivers (n=28 intervention group (IG), n=27 control group (CG)) with protein intake of under 1.2 g/kgBW/d at baseline. 45.5% were male (n=12 male intervention group (MIG), n=13 male control group (MCG)). Intervention: During the six-month intervention tailored nutritional guidance was given to the intervention group during home visit (once) and in group meetings (2-4 times), complemented with written material. Written material was offered to control group. Measurements: Protein intake was assessed with three-day food diary at baseline and final measurements. Main outcome measure was change in protein intake (g/kg bodyweight (BW)/d), analysed among participants with protein intake under 1.2 g/kgBW/d at baseline. Participant characteristics were evaluated with validated methods. Results: Mean protein intake was 0.86 g/kgBW/d in IG and 0.85 g/kgBW/d in CG and among males, 0.89 g/kgBW/d in MIG and 0.79 g/kgBW/d in MCG. There was no significant difference in the change in protein intake between IG and CG. Protein intake increased among MIG by 0.11 g/kgBW/d and decreased in MCG group by -0.07 g/kgBW/d, p=0.007. There was also a significant increase in protein intake within the IG (+0.10 g/kgBW/d, p=0.038). Conclusions: Tailored nutritional guidance resulted in improved protein intake among older male caregivers. Group-based nutritional guidance may boost nutrition among older caregivers, especially males.
背景:老年照顾者,尤其是男性,容易出现营养问题。蛋白质摄入量低是常见的,会影响他们的营养和健康。目的:本随机对照试验的目的是研究量身定制的营养指导对≥65岁、蛋白质摄入量符合推荐值(≤1.2 g/kgBW/d)的护理人员蛋白质摄入量的影响。对男性照顾者进行亚组分析。设计:数据来自卡伦营养随机对照试验(RCT)。研究对象:来自芬兰西部的社区护理人员。参与者:55名护理人员(n=28干预组(IG), n=27对照组(CG)),基线蛋白质摄入量低于1.2 g/kgBW/d。45.5%为男性,其中干预组(MIG) 12例,对照组(MCG) 13例。干预:在六个月的干预期间,在家访期间(一次)和小组会议期间(2-4次)为干预组提供量身定制的营养指导,并辅以书面材料。给对照组提供书面材料。测量:在基线和最终测量时,用三天的食物日记评估蛋白质摄入量。主要结局指标是蛋白质摄入量(g/kg体重(BW)/d)的变化,在基线时蛋白质摄入量低于1.2 g/kgBW/d的参与者中进行分析。采用有效的方法评估参与者的特征。结果:平均蛋白质摄取量为:IG组0.86 g/kgBW/d, CG组0.85 g/kgBW/d, mg组0.89 g/kgBW/d, MCG组0.79 g/kgBW/d。IG组和CG组的蛋白质摄取量变化无显著差异。蛋白质摄取量在MIG组增加0.11 g/kgBW/d, MCG组减少-0.07 g/kgBW/d, p=0.007。IG内蛋白质摄取量显著增加(+0.10 g/kgBW/d, p=0.038)。结论:量身定制的营养指导可以改善老年男性照顾者的蛋白质摄入量。以群体为基础的营养指导可以促进老年护理人员的营养,尤其是男性。
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引用次数: 5
KNOWLEDGE AND PRACTICES GOVERNING THE IMPLEMENTATION OF NASOGASTRIC TUBE FEEDING AS A TEMPORARY UNDERNUTRITION MANAGEMENT MEASURE IN ACUTE GERIATRIC CARE: A QUALITATIVE RESEARCH-BASED ANALYSIS 知识和实践管理实施鼻胃管喂养作为一个临时营养不良管理措施在急性老年护理:定性研究为基础的分析
Pub Date : 2018-01-01 DOI: 10.14283/jarcp.2018.20
E. Fercot, L. Marty, C. Bouteloup, Y. Lepley, J. Bohatier, M. Bonnefoy, B. Lesourd, Y. Boirie, S. Dadet
Introduction: Nasogastric tube feeding appears underused in acute geriatric care units. The objective of this study was to identify the knowledge, practice, fears or behaviors of care givers governing implementation. Material and Methods: Multicentric qualitative research study based on interviews with geriatricians and care staff. Coding of patterns and thematic analysis of the data were used to extract key concepts tied to the objective. Results: Ten geriatricians and eleven care staff were interviewed individually and in a focus-group setting. Undernutrition was perceived as a prognosis-worsening comorbidity, not a disease. Early screening for undernutrition appeared essential, but care management and monitoring was within the remit of downstream structures. A handful of indications are reported to justify moves to start nasogastric tube feeding, often as part of adjuvant care, when real benefit is expected, when the individualized feeding plan is part of a comprehensive care plan, with the patient consciously involved and after consulting with the family. Patients' fear of complications, cognitive disorders, and uncertain life expectancy often fuel concerns of a form of unreasonable obstinacy. Finally, doctors and care staff alike think that decisions on nasogastric intubation in this patient population require a multidisciplinary-team process. Conclusion: Nasogastric tube feeding in acute geriatric care remains fraught with issues. It looks a viable option, but should be part of a comprehensive care plan, based on multidisciplinary decision-making by appropriately-trained teams, where the goals of care are the patient's comfort and quality of life.
鼻胃管喂养似乎在急性老年护理单位使用不足。本研究的目的是确定护理人员管理实施的知识、实践、恐惧或行为。材料和方法:多中心的定性研究,基于对老年病医生和护理人员的访谈。使用模式编码和数据的专题分析来提取与目标相关的关键概念。结果:对10名老年病医生和11名护理人员进行了单独和焦点小组访谈。营养不良被认为是恶化预后的合并症,而不是疾病。营养不良的早期筛查似乎是必不可少的,但护理管理和监测属于下游结构的职权范围。据报道,少数适应症证明开始鼻胃管喂养是合理的,通常作为辅助护理的一部分,当预期真正受益时,当个体化喂养计划是综合护理计划的一部分时,患者有意识地参与并与家人协商后。患者对并发症、认知障碍和不确定的预期寿命的恐惧,常常引发对某种形式的不合理固执的担忧。最后,医生和护理人员都认为,对这类患者进行鼻胃插管的决定需要一个多学科团队的过程。结论:鼻胃管喂养在急性老年护理中仍存在诸多问题。这看起来是一个可行的选择,但应该是一个综合护理计划的一部分,基于多学科的决策,由适当训练的团队,其中护理的目标是病人的舒适和生活质量。
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引用次数: 0
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