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Assessing the Application of Large Language Models in Generating Dermatologic Patient Education Materials According to Reading Level: Qualitative Study. 根据阅读水平评估大语言模型在生成皮肤科患者教育材料中的应用:定性研究。
Q3 Medicine Pub Date : 2024-05-16 DOI: 10.2196/55898
Raphaella Lambert, Zi-Yi Choo, Kelsey Gradwohl, Liesl Schroedl, Arlene Ruiz De Luzuriaga
<p><strong>Background: </strong>Dermatologic patient education materials (PEMs) are often written above the national average seventh- to eighth-grade reading level. ChatGPT-3.5, GPT-4, DermGPT, and DocsGPT are large language models (LLMs) that are responsive to user prompts. Our project assesses their use in generating dermatologic PEMs at specified reading levels.</p><p><strong>Objective: </strong>This study aims to assess the ability of select LLMs to generate PEMs for common and rare dermatologic conditions at unspecified and specified reading levels. Further, the study aims to assess the preservation of meaning across such LLM-generated PEMs, as assessed by dermatology resident trainees.</p><p><strong>Methods: </strong>The Flesch-Kincaid reading level (FKRL) of current American Academy of Dermatology PEMs was evaluated for 4 common (atopic dermatitis, acne vulgaris, psoriasis, and herpes zoster) and 4 rare (epidermolysis bullosa, bullous pemphigoid, lamellar ichthyosis, and lichen planus) dermatologic conditions. We prompted ChatGPT-3.5, GPT-4, DermGPT, and DocsGPT to "Create a patient education handout about [condition] at a [FKRL]" to iteratively generate 10 PEMs per condition at unspecified fifth- and seventh-grade FKRLs, evaluated with Microsoft Word readability statistics. The preservation of meaning across LLMs was assessed by 2 dermatology resident trainees.</p><p><strong>Results: </strong>The current American Academy of Dermatology PEMs had an average (SD) FKRL of 9.35 (1.26) and 9.50 (2.3) for common and rare diseases, respectively. For common diseases, the FKRLs of LLM-produced PEMs ranged between 9.8 and 11.21 (unspecified prompt), between 4.22 and 7.43 (fifth-grade prompt), and between 5.98 and 7.28 (seventh-grade prompt). For rare diseases, the FKRLs of LLM-produced PEMs ranged between 9.85 and 11.45 (unspecified prompt), between 4.22 and 7.43 (fifth-grade prompt), and between 5.98 and 7.28 (seventh-grade prompt). At the fifth-grade reading level, GPT-4 was better at producing PEMs for both common and rare conditions than ChatGPT-3.5 (P=.001 and P=.01, respectively), DermGPT (P<.001 and P=.03, respectively), and DocsGPT (P<.001 and P=.02, respectively). At the seventh-grade reading level, no significant difference was found between ChatGPT-3.5, GPT-4, DocsGPT, or DermGPT in producing PEMs for common conditions (all P>.05); however, for rare conditions, ChatGPT-3.5 and DocsGPT outperformed GPT-4 (P=.003 and P<.001, respectively). The preservation of meaning analysis revealed that for common conditions, DermGPT ranked the highest for overall ease of reading, patient understandability, and accuracy (14.75/15, 98%); for rare conditions, handouts generated by GPT-4 ranked the highest (14.5/15, 97%).</p><p><strong>Conclusions: </strong>GPT-4 appeared to outperform ChatGPT-3.5, DocsGPT, and DermGPT at the fifth-grade FKRL for both common and rare conditions, although both ChatGPT-3.5 and DocsGPT performed better than GPT-4 at the sevent
背景:皮肤科患者教育材料(PEM)的编写水平通常高于全国七至八年级的平均阅读水平。ChatGPT-3.5、GPT-4、DermGPT 和 DocsGPT 是大型语言模型 (LLM),可响应用户提示。我们的项目评估了它们在特定阅读水平下生成皮肤病学 PEM 的使用情况:本研究旨在评估精选 LLM 在未指定和指定阅读水平下生成常见和罕见皮肤病 PEM 的能力。此外,该研究还旨在评估由皮肤科住院受训者评估的由 LLM 生成的 PEM 的意义保持情况:方法:针对 4 种常见皮肤病(特应性皮炎、寻常痤疮、银屑病和带状疱疹)和 4 种罕见皮肤病(表皮松解症、丘疹性类风湿关节炎、板层状鱼鳞病和扁平苔藓),评估了美国皮肤病学会当前 PEM 的 Flesch-Kincaid 阅读水平 (FKRL)。我们提示 ChatGPT-3.5、GPT-4、DermGPT 和 DocsGPT "在[FKRL]下创建一份关于[病症]的患者教育手册",从而在未指定的五年级和七年级 FKRL 下为每种病症反复生成 10 份 PEM,并通过 Microsoft Word 可读性统计进行评估。由 2 名皮肤科住院受训者对各 LLM 的意义保持情况进行评估:目前美国皮肤病学会的 PEM 对于常见病和罕见病的平均(标清)FKRL 分别为 9.35 (1.26) 和 9.50 (2.3)。就常见疾病而言,LLM 制作的 PEM 的 FKRL 介于 9.8 至 11.21 之间(未指定提示),介于 4.22 至 7.43 之间(五级提示),以及介于 5.98 至 7.28 之间(七级提示)。对于罕见疾病,LLM 制作的 PEM 的 FKRL 在 9.85 到 11.45 之间(未指定提示),在 4.22 到 7.43 之间(五年级提示),在 5.98 到 7.28 之间(七年级提示)。在五年级阅读水平上,GPT-4 在常见和罕见情况下的 PEM 生成能力均优于 ChatGPT-3.5(P=.001 和 P=.01)和 DermGPT(P.05);但在罕见情况下,ChatGPT-3.5 和 DocsGPT 的表现优于 GPT-4(P=.003 和 PConclusions):就常见和罕见病症而言,GPT-4 在五年级 FKRL 中的表现似乎优于 ChatGPT-3.5、DocsGPT 和 DermGPT,但就罕见病症而言,ChatGPT-3.5 和 DocsGPT 在七年级 FKRL 中的表现均优于 GPT-4。由 LLM 制作的 PEM 可以可靠地满足某些常见和罕见皮肤病的七级 FKRL 要求,而且易于阅读,患者可以理解,大部分情况下也很准确。LLM 可在提高皮肤病学领域的健康素养和传播易读、易懂的 PEM 方面发挥作用。
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引用次数: 0
Online Patient Attitudes Toward Cutaneous Immune-Related Adverse Events Attributed to Nivolumab and Pembrolizumab: Sentiment Analysis. 在线患者对 Nivolumab 和 Pembrolizumab 引起的皮肤免疫相关不良事件的态度:情感分析。
Q3 Medicine Pub Date : 2024-05-02 DOI: 10.2196/53792
Camille M Powers, Andrew K Yang, Hannah Verma, Jeremy Orloff, Austin J Piontkowski, Nicholas Gulati
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引用次数: 0
A Survey of Demographics and Treatments in Melanoma Case Reports: Retrospective Bibliometric Analysis. 黑色素瘤病例报告中的人口统计学和治疗方法调查:回顾性文献计量分析
Q3 Medicine Pub Date : 2024-04-22 DOI: 10.2196/56684
Ross O'Hagan, Jessie Ngandjui, Benjamin Ungar, J. Ungar, N. Gulati
Melanoma case reports show variations in treatment by age and sex.
黑色素瘤病例报告显示,治疗方法因年龄和性别而异。
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引用次数: 0
Ichthyosiform Lichen Planus Pigmentosus in a 19-Year-Old Male Patient: Case Report. 一名 19 岁男性患者的鱼鳞状扁平苔癣色素沉着症:病例报告。
Q3 Medicine Pub Date : 2024-04-19 DOI: 10.2196/50429
Audi Sugiharto, J. Gatmaitan, Johannes Dayrit
Lichen planus pigmentosus (LPP) is a condition characterized by persistent and asymptomatic brownish-black-to-blue or purple-gray pigmentation, predominantly in the face and sun-exposed areas, commonly in dark-skinned individuals. Several clinical variants of LPP have been reported. However, the ichthyosiform type of LPP has not been reported. We present a 19-year-old male patient who presented with a 7-year history of asymptomatic grayish macules; patches with fine scales on the face, trunk, and upper extremities; and grayish plaques with thick "ichthyosiform" scales on the lower extremities. The diagnosis of LPP was proven by histopathological findings on both the macular and ichthyosiform plaques. Cluster differentiation (CD) 68 stain highlights the same density of pigment-laden macrophages in both the gray macule and the ichthyosiform plaque. The cause of LPP is unknown. Transcription factor anomalies may play a role in increased keratinization of lichen planus lesions. It can be assumed that the mechanism of the altered distribution of keratinization may occur on the ichthyosiform lesions in this patient. The terminology "ichthyosiform lichen planus pigmentosus" is hereby proposed to be added to the clinical variants of LPP.
扁平苔藓色素沉着症(LPP)是一种以持续性、无症状的棕黑色至蓝色或紫灰色色素沉着为特征的疾病,主要发生在面部和暴露于阳光的部位,常见于深肤色人群。据报道,鱼鳞病有多种临床变异。然而,鱼鳞病的鱼鳞状类型尚未见报道。我们为大家介绍一位 19 岁的男性患者,他有 7 年的病史,面部、躯干和上肢出现无症状的灰白色斑块和带有细小鳞屑的斑块,下肢出现灰色斑块和厚厚的 "鱼鳞状 "鳞屑。斑丘疹和鱼鳞状斑块的组织病理学检查结果证明了 LPP 的诊断。集束分化(CD)68染色显示,灰色斑块和鱼鳞状斑块中色素沉着巨噬细胞的密度相同。LPP病因不明。转录因子异常可能是导致扁平苔藓皮损角质化增加的原因之一。可以推测,角化分布改变的机制可能发生在该患者的鱼鳞状皮损上。因此,建议在扁平苔藓的临床变异中增加 "鱼鳞状扁平苔藓色素沉着症 "这一术语。
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引用次数: 0
From the Cochrane Library: Leukotriene Receptor Antagonists for Eczema. 来自 Cochrane 图书馆:治疗湿疹的白三烯受体拮抗剂。
Q3 Medicine Pub Date : 2024-04-12 DOI: 10.2196/50434
Lauren Marie Toledo, Ramiro Rodriguez, Torunn E Sivesind, Efstratios Vakirlis, Reiji Kojima, Robert P Dellavalle
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引用次数: 0
The New Media Landscape and Its Effects on Skin Cancer Diagnostics, Prognostics, and Prevention: Scoping Review. 新媒体格局及其对皮肤癌诊断、预后和预防的影响:范围审查。
Q3 Medicine Pub Date : 2024-04-08 DOI: 10.2196/53373
Priscilla L Haff, Alli Jacobson, Madison M Taylor, Hayden P Schandua, David P Farris, Hung Q Doan, Kelly C Nelson

Background: The wide availability of web-based sources, including social media (SM), has supported rapid, widespread dissemination of health information. This dissemination can be an asset during public health emergencies; however, it can also present challenges when the information is inaccurate or ill-informed. Of interest, many SM sources discuss cancer, specifically cutaneous melanoma and keratinocyte cancers (basal cell and squamous cell carcinoma).

Objective: Through a comprehensive and scoping review of the literature, this study aims to gain an actionable perspective of the state of SM information regarding skin cancer diagnostics, prognostics, and prevention.

Methods: We performed a scoping literature review to establish the relationship between SM and skin cancer. A literature search was conducted across MEDLINE, Embase, Cochrane Library, Web of Science, and Scopus from January 2000 to June 2023. The included studies discussed SM and its relationship to and effect on skin cancer.

Results: Through the search, 1009 abstracts were initially identified, 188 received full-text review, and 112 met inclusion criteria. The included studies were divided into 7 groupings based on a publication's primary objective: misinformation (n=40, 36%), prevention campaign (n=19, 17%), engagement (n=16, 14%), research (n=12, 11%), education (n=11, 10%), demographics (n=10, 9%), and patient support (n=4, 3%), which were the most common identified themes.

Conclusions: Through this review, we gained a better understanding of the SM environment addressing skin cancer information, and we gained insight into the best practices by which SM could be used to positively influence the health care information ecosystem.

背景:包括社交媒体 (SM) 在内的网络信息源的广泛使用支持了卫生信息的快速、广泛传播。在发生公共卫生突发事件时,这种传播方式可以成为一种资产;但是,当信息不准确或信息不足时,它也会带来挑战。值得关注的是,许多 SM 信息源都讨论了癌症,特别是皮肤黑色素瘤和角质细胞癌(基底细胞癌和鳞状细胞癌):本研究旨在通过对文献进行全面的范围性综述,从可操作的角度了解有关皮肤癌诊断、预后和预防的 SM 信息现状:我们进行了范围性文献综述,以确定 SM 与皮肤癌之间的关系。我们对 2000 年 1 月至 2023 年 6 月期间的 MEDLINE、Embase、Cochrane Library、Web of Science 和 Scopus 进行了文献检索。纳入的研究讨论了 SM 及其与皮肤癌的关系和对皮肤癌的影响:通过检索,初步确定了 1009 篇摘要,188 篇接受了全文审阅,112 篇符合纳入标准。根据出版物的主要目标,纳入的研究分为 7 组:错误信息(40 篇,占 36%)、预防运动(19 篇,占 17%)、参与(16 篇,占 14%)、研究(12 篇,占 11%)、教育(11 篇,占 10%)、人口统计(10 篇,占 9%)和患者支持(4 篇,占 3%),这些是最常见的主题:通过本次综述,我们更好地了解了处理皮肤癌信息的 SM 环境,并深入了解了 SM 可用来积极影响医疗保健信息生态系统的最佳做法。
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引用次数: 0
Merkel Cell Carcinoma on the Face: Case Report. 面部梅克尔细胞癌:病例报告。
Q3 Medicine Pub Date : 2024-04-08 DOI: 10.2196/56658
Shaikha Salah Alhaj, Fatma Abdulghaffar Qaderi, Tarek Ibrahim, Maha Almohammad

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine skin tumor that presents as a flesh-colored or bluish-red nodule on the face, neck, or head. Long-term ultraviolet radiation exposure and Merkel cell polyomavirus are associated with MCC pathogenesis. We present a case of MCC on the right cheek in a male patient aged 87 years. Our primary goal in presenting the case is to bring MCC, which is a diagnostic challenge, to the notice of dermatologists and oncologists, as early detection and prompt treatment are important. The patient had a significant past medical history, including diabetes mellitus, hypertension, dyslipidemia, stage 3 chronic kidney disease, benign prostatic hyperplasia, chronic hyponatremia, acute pancreatitis, essential thrombocytosis on hydroxyurea, and ischemic heart disease. The patient presented with a mildly swollen right upper lip showing a poorly defined, relatively homogeneous subcutaneous lesion with a history of persistence for 1.5 months. The clinical examination revealed a 5 × 3-cm nodular lesion on the right side of the cheek with swelling of the right upper lip. Immunohistochemistry markers and histopathological features confirmed the diagnosis of MCC. The patient was referred to the oncology department for further management. MCC of the skin is an aggressive lesion with a high risk of metastasis and recurrence, which is more common in immunocompromised people. Prompt management and treatment of MCC is essential because if left untreated, it can spread to other parts of the body and can also metastasize to lymph nodes and other organs. The patient is 87 years old and has a significant past medical history of diabetes mellitus, hypertension, dyslipidemia, chronic kidney disease stage 3, benign prostatic hyperplasia, chronic hyponatremia, acute pancreatitis, essential thrombocytosis on hydroxyurea, and ischemic heart disease. Currently, the patient presented with a mildly swollen right upper lip showing a poorly defined, relatively homogenous subcutaneous lesion with a history of persistence for 1.5 months. The clinical examination revealed a 5x3 cm nodular lesion on the right side of the cheek with swelling of the right upper lip. Immunohistochemistry markers results and histopathological features confirmed the diagnosis of Merkel cell carcinoma. The patient was referred to the oncology department for further management. Merkel cell carcinoma of the skin is an aggressive lesion with a high risk of metastasis and recurrence, which is more common in immunocompromised people. Prompt management and treatment of Merkel cell carcinoma is essential because if left untreated, it can spread to other parts of the body and can also metastasize to lymph nodes and other organs.

非结构化:背景:梅克尔细胞癌(MCC)是一种罕见的原发性神经内分泌皮肤肿瘤,表现为面部、颈部或头部的肉色或蓝红色结节。长期暴露于紫外线(UV)辐射和梅克尔细胞多瘤病毒(MCV)与梅克尔细胞癌的发病机制有关。我们为您介绍一例 87 岁男性患者的右脸颊梅克尔细胞癌病例。目的:本病例的主要目的是让皮肤科医生和肿瘤科医生注意到梅克尔细胞癌这一诊断难题,因为早期发现和及时治疗非常重要。病例报告:患者 87 岁,有糖尿病、高血压、血脂异常、慢性肾病 3 期、良性前列腺增生、慢性低钠血症、急性胰腺炎、服用羟基脲后出现血小板增多和缺血性心脏病等严重病史。目前,患者右上唇轻度肿胀,皮下病变界限不清,相对均匀,病史持续 1.5 个月。临床检查发现,患者右侧脸颊有一个 5x3 厘米的结节性病变,右上唇肿胀。免疫组化标记结果和组织病理学特征证实了梅克尔细胞癌的诊断。患者被转到肿瘤科接受进一步治疗。结论皮肤梅克尔细胞癌是一种侵袭性病变,转移和复发的风险很高,在免疫力低下的人群中更为常见。如果不及时治疗,梅克尔细胞癌可能会扩散到身体其他部位,也可能转移到淋巴结和其他器官,因此及时处理和治疗梅克尔细胞癌至关重要。
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引用次数: 0
Social Media Use in Dermatology in Turkey: Challenges and Tips for Patient Health. 土耳其皮肤科的社交媒体使用:患者健康面临的挑战和建议。
Q3 Medicine Pub Date : 2024-03-28 DOI: 10.2196/51267
Ayse Serap Karadag, Basak Kandi, Berna Sanlı, Hande Ulusal, Hasan Basusta, Seray Sener, Sinem Calıka

Social media has established its place in our daily lives, especially with the advent of the COVID-19 pandemic. It has become the leading source of information for dermatological literacy on various topics, ranging from skin diseases to everyday skincare and cosmetic purposes in the present digital era. Accumulated evidence indicates that accurate medical content constitutes only a tiny fraction of the exponentially growing dermatological information on digital platforms, highlighting an unmet patient need for access to evidence-based information on social media. However, there have been no recent local publications from Turkey analyzing and assessing the key elements in raising dermatological literacy and awareness in digital communication for patients. To the best of our knowledge, this study is the first collaborative work between health care professionals and a social media specialist in the medical literature. Furthermore, it represents the first author-initiated implementation science attempt focusing on the use of social media in addressing dermatological problems, with the primary end point of increasing health literacy and patient benefits. The multidisciplinary expert panel was formed by 4 dermatologists with academic credentials and significant influence in public health and among patients on digital platforms. A social media specialist, who serves as a guest lecturer on "How social media works" at Istanbul Technical University, Turkey, was invited to the panel as an expert on digital communication. The panel members had a kickoff meeting to establish the context for the discussion points. The context of the advisory board meeting was outlined under 5 headlines. Two weeks later, the panel members presented their social media account statistics, defined the main characteristics of dermatology patients on social media, and discussed their experiences with patients on digital platforms. These discussions were organized under the predefined headlines and in line with the current literature. We aimed to collect expert opinions on identifying the main characteristics of individuals interested in dermatological topics and to provide recommendations to help dermatologists increase evidence-based dermatological content on social media. Additionally, experts discussed paradigms for dermatological outreach and the role of dermatologists in reducing misleading information on digital platforms in Turkey. The main concluding remark of this study is that dermatologists should enhance their social media presence to increase evidence-based knowledge by applying the principles of patient-physician communication on digital platforms while maintaining a professional stance. To achieve this goal, dermatologists should share targeted scientific content after increasing their knowledge about the operational rules of digital channels. This includes correctly identifying the needs of those seeking information on social media and preparing a sustainable s

社交媒体已经在我们的日常生活中占据了一席之地,尤其是随着 COVID-19 大流行的到来。在当今的数字时代,它已成为皮肤病知识的主要信息来源,涉及从皮肤病到日常护肤和美容等各种主题。积累的证据表明,准确的医疗内容只占数字平台上急剧增长的皮肤病信息的一小部分,这突出表明患者对在社交媒体上获取循证信息的需求尚未得到满足。然而,土耳其近期还没有本地出版物分析和评估在数字通信中提高患者皮肤病知识和意识的关键因素。据我们所知,本研究是医学文献中第一部由医疗保健专业人士和社交媒体专家合作完成的作品。此外,这也是作者发起的首次实施科学尝试,其重点是利用社交媒体解决皮肤病问题,主要目的是提高健康素养和患者受益。多学科专家小组由 4 位皮肤科医生组成,他们都具有学术资质,在公共卫生领域和数字平台患者中具有重要影响力。一位在土耳其伊斯坦布尔技术大学担任 "社交媒体如何运作 "客座讲师的社交媒体专家作为数字通信专家应邀参加了专家小组。小组成员举行了一次启动会议,以确定讨论要点的背景。在 5 个标题下概述了咨询委员会会议的背景。两周后,小组成员展示了他们的社交媒体账户统计数据,定义了社交媒体上皮肤科患者的主要特征,并讨论了他们在数字平台上与患者交流的经验。这些讨论都是在预先确定的标题下进行的,并与当前的文献相一致。我们旨在收集专家意见,以确定对皮肤病话题感兴趣的人的主要特征,并提供建议,帮助皮肤科医生在社交媒体上增加循证皮肤病内容。此外,专家们还讨论了皮肤病外联范例以及皮肤科医生在减少土耳其数字平台上误导性信息方面的作用。本研究的主要结论是,皮肤科医生应通过在数字平台上应用医患沟通原则,同时保持专业立场,加强其在社交媒体上的存在,以增加循证知识。为实现这一目标,皮肤科医生应在进一步了解数字渠道的操作规则后,分享有针对性的科学内容。这包括正确识别在社交媒体上寻求信息者的需求,并制定可持续的社交媒体交流计划。这一观点反映了土耳其皮肤科医生在当地数字平台上搜索皮肤科信息的经验;因此,建议的适用性可能有限,应仔细斟酌。
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引用次数: 0
Inequities in Technology Access and Digital Health Literacy Among Patients With Dermatologic Conditions: Cross-Sectional Analysis of the National Health Interview Survey. 皮肤病患者在获取技术和数字健康知识方面的不平等:全国健康访谈调查的横断面分析。
Q3 Medicine Pub Date : 2024-03-22 DOI: 10.2196/51511
Danny Linggonegoro, Kathryn Williams, Madeline Hlobik, Jennifer Huang

Certain sociodemographic factors are associated with low technology access and digital healthy literacy.

某些社会人口因素与技术普及率低和数字健康素养低有关。
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引用次数: 0
The Potential of Exercise on Lifestyle and Skin Function: Narrative Review. 运动对生活方式和皮肤功能的潜能:叙述性评论。
Q3 Medicine Pub Date : 2024-03-14 DOI: 10.2196/51962
Ryosuke Oizumi, Yoshie Sugimoto, Hiromi Aibara

Background: The skin is an important organ of the human body and has moisturizing and barrier functions. Factors such as sunlight and lifestyle significantly affect these skin functions, with sunlight being extremely damaging. The effects of lifestyle habits such as smoking, diet, and sleep have been studied extensively. It has been found that smoking increases the risk of wrinkles, while excessive fat and sugar intake leads to skin aging. Lack of sleep and stress are also dangerous for the skin's barrier function. In recent years, the impact of exercise habits on skin function has been a focus of study. Regular exercise is associated with increased blood flow to the skin, elevated skin temperature, and improved skin moisture. Furthermore, it has been shown to improve skin structure and rejuvenate its appearance, possibly through promoting mitochondrial biosynthesis and affecting hormone secretion. Further research is needed to understand the effects of different amounts and content of exercise on the skin.

Objective: This study aims to briefly summarize the relationship between lifestyle and skin function and the mechanisms that have been elucidated so far and introduce the expected effects of exercise on skin function.

Methods: We conducted a review of the literature using PubMed and Google Scholar repositories for relevant literature published between 2000 and 2022 with the following keywords: exercise, skin, and life habits.

Results: Exercise augments the total spectrum power density of cutaneous blood perfusion by a factor of approximately 8, and vasodilation demonstrates an enhancement of approximately 1.5-fold. Regular exercise can also mitigate age-related skin changes by promoting mitochondrial biosynthesis. However, not all exercise impacts are positive; for instance, swimming in chlorinated pools may harm the skin barrier function. Hence, the exercise environment should be considered for its potential effects on the skin.

Conclusions: This review demonstrates that exercise can potentially enhance skin function retention.

背景:皮肤是人体的重要器官,具有保湿和屏障功能:皮肤是人体的重要器官,具有保湿和屏障功能。阳光和生活方式等因素会严重影响皮肤的这些功能,其中阳光对皮肤的伤害最大。吸烟、饮食和睡眠等生活习惯的影响已被广泛研究。研究发现,吸烟会增加出现皱纹的风险,而过多的脂肪和糖分摄入会导致皮肤老化。睡眠不足和压力也会危害皮肤的屏障功能。近年来,运动习惯对皮肤功能的影响成为研究重点。经常运动与皮肤血流量增加、皮肤温度升高和皮肤水分改善有关。此外,运动还能改善皮肤结构,使皮肤焕发青春,这可能是通过促进线粒体生物合成和影响荷尔蒙分泌实现的。要了解不同运动量和运动内容对皮肤的影响,还需要进一步的研究:本研究旨在简要总结生活方式与皮肤功能之间的关系以及目前已阐明的机制,并介绍运动对皮肤功能的预期影响:我们利用PubMed和谷歌学术资料库对2000年至2022年间发表的相关文献进行了综述,关键词包括:运动、皮肤和生活习惯:结果:运动可将皮肤血液灌注的总谱功率密度提高约 8 倍,而血管扩张则提高约 1.5 倍。经常运动还能促进线粒体的生物合成,从而缓解与年龄有关的皮肤变化。然而,并非所有运动都有积极影响,例如,在氯化泳池中游泳可能会损害皮肤屏障功能。因此,应考虑运动环境对皮肤的潜在影响:本综述表明,运动有可能增强皮肤功能的保持力。
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引用次数: 0
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