首页 > 最新文献

JMIR dermatology最新文献

英文 中文
Lichen Planus Pigmentosus and Vitiligo in a 61-Year-Old Filipino Man: Case Report. 61岁菲律宾男性色素性扁平苔藓合并白癜风1例。
Q3 Medicine Pub Date : 2024-11-29 DOI: 10.2196/50401
Maria Isabel Belizario, Julius Garcia Gatmaitan, Johannes Dayrit

Unlabelled: Pigmentary disorders have been implicated in causing psychosocial turmoil in patients as they can cause some degree of cosmetic disfigurement. Lichen planus pigmentosus (LPP) presents as ashy, dermatosis-like eruptions on sun-exposed areas, particularly on the head, neck, and earlobes. On the other hand, vitiligo is a chronic disorder that appears as depigmented patches on the skin. A 61-year-old man with Fitzpatrick skin phototype IV presented to us initially with LPP but eventually also developed vitiligo. The patient was treated with low-dose oral isotretinoin for LPP and topical tacrolimus 0.1% ointment for both LPP and vitiligo with a good clinical outcome. One case of segmental vitiligo and zosteriform LPP, affecting a 22-year-old Indian woman, has been previously reported in the English-language literature. An autoimmune etiology that causes melanocytorrhagy may be a plausible hypothesis for the coexistence of these 2 conditions.

未标记:色素紊乱与患者的心理社会混乱有关,因为它们可能导致某种程度的美容毁容。色素性扁平苔藓(LPP)表现为暴露在阳光下的部位,特别是头部、颈部和耳垂上的灰白色、皮肤病样的皮疹。另一方面,白癜风是一种慢性疾病,表现为皮肤上的色素沉着斑块。一名61岁男性Fitzpatrick皮肤光型IV患者最初表现为LPP,但最终发展为白癜风。患者口服低剂量异维甲酸治疗LPP,外用0.1%他克莫司软膏治疗LPP和白癜风,临床结果良好。英语文献中曾报道过一例节段性白癜风和带状虫状LPP,影响一名22岁的印度妇女。引起黑素细胞增生的自身免疫性病因可能是这两种情况共存的合理假设。
{"title":"Lichen Planus Pigmentosus and Vitiligo in a 61-Year-Old Filipino Man: Case Report.","authors":"Maria Isabel Belizario, Julius Garcia Gatmaitan, Johannes Dayrit","doi":"10.2196/50401","DOIUrl":"10.2196/50401","url":null,"abstract":"<p><strong>Unlabelled: </strong>Pigmentary disorders have been implicated in causing psychosocial turmoil in patients as they can cause some degree of cosmetic disfigurement. Lichen planus pigmentosus (LPP) presents as ashy, dermatosis-like eruptions on sun-exposed areas, particularly on the head, neck, and earlobes. On the other hand, vitiligo is a chronic disorder that appears as depigmented patches on the skin. A 61-year-old man with Fitzpatrick skin phototype IV presented to us initially with LPP but eventually also developed vitiligo. The patient was treated with low-dose oral isotretinoin for LPP and topical tacrolimus 0.1% ointment for both LPP and vitiligo with a good clinical outcome. One case of segmental vitiligo and zosteriform LPP, affecting a 22-year-old Indian woman, has been previously reported in the English-language literature. An autoimmune etiology that causes melanocytorrhagy may be a plausible hypothesis for the coexistence of these 2 conditions.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e50401"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142756035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of ChatGPT in Educating Patients and Clinicians About Skin Toxicities Associated With Cancer Treatment. ChatGPT 在教育患者和临床医生了解癌症治疗相关皮肤毒性方面的功效。
Q3 Medicine Pub Date : 2024-11-20 DOI: 10.2196/54919
Annie Chang, Jade Young, Andrew Para, Angela Lamb, Nicholas Gulati

Unlabelled: This study investigates the application of ChatGPT, an artificial intelligence tool, in providing information on skin toxicities associated with cancer treatments, highlighting that while ChatGPT can serve as a valuable resource for clinicians, its use for patient education requires careful consideration due to the complex nature of the information provided.

无标签:本研究调查了人工智能工具 ChatGPT 在提供与癌症治疗相关的皮肤毒性信息方面的应用,强调虽然 ChatGPT 可作为临床医生的宝贵资源,但由于所提供信息的复杂性,将其用于患者教育需要慎重考虑。
{"title":"Efficacy of ChatGPT in Educating Patients and Clinicians About Skin Toxicities Associated With Cancer Treatment.","authors":"Annie Chang, Jade Young, Andrew Para, Angela Lamb, Nicholas Gulati","doi":"10.2196/54919","DOIUrl":"10.2196/54919","url":null,"abstract":"<p><strong>Unlabelled: </strong>This study investigates the application of ChatGPT, an artificial intelligence tool, in providing information on skin toxicities associated with cancer treatments, highlighting that while ChatGPT can serve as a valuable resource for clinicians, its use for patient education requires careful consideration due to the complex nature of the information provided.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e54919"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11600653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Dermatologists Can Aid Nondermatologic Professionals Using the Figure 1 App: Case Analysis. 皮肤科医生如何使用图1应用程序帮助非皮肤科专业人员:案例分析。
Q3 Medicine Pub Date : 2024-11-13 DOI: 10.2196/60500
Alexis Coican, Nathaniel A Marroquin, Alexa Carboni, Sara Holt, Morgan Zueger

Unlabelled: We found that third-party apps such as Figure 1 were used predominantly by nondermatologist medical personnel for collaboration in medical decision-making related to dermatologic conditions conducted with other health care providers. This finding calls attention to the need for more readily available resources for nondermatologist health care providers encountering patients with skin-related conditions, with the added benefits of trained dermatologists being allies on such medical app platforms, and the platform allowing for recognition of instances when additional consultation or referral to trained dermatologists for more complex cases is appropriate.

未标记:我们发现第三方应用程序(如图1)主要由非皮肤科医疗人员使用,用于与其他医疗保健提供者协作进行与皮肤病相关的医疗决策。这一发现引起了人们对非皮肤科医生医疗保健提供者遇到皮肤相关疾病患者时需要更容易获得的资源的关注,训练有素的皮肤科医生在此类医疗应用平台上的盟友的额外好处,以及该平台允许识别实例,以便在更复杂的病例中进行额外咨询或转介给训练有素的皮肤科医生。
{"title":"How Dermatologists Can Aid Nondermatologic Professionals Using the <i>Figure 1</i> App: Case Analysis.","authors":"Alexis Coican, Nathaniel A Marroquin, Alexa Carboni, Sara Holt, Morgan Zueger","doi":"10.2196/60500","DOIUrl":"https://doi.org/10.2196/60500","url":null,"abstract":"<p><strong>Unlabelled: </strong>We found that third-party apps such as Figure 1 were used predominantly by nondermatologist medical personnel for collaboration in medical decision-making related to dermatologic conditions conducted with other health care providers. This finding calls attention to the need for more readily available resources for nondermatologist health care providers encountering patients with skin-related conditions, with the added benefits of trained dermatologists being allies on such medical app platforms, and the platform allowing for recognition of instances when additional consultation or referral to trained dermatologists for more complex cases is appropriate.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e60500"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Adverse Effects From Diabetes Devices in Pediatric Patients With Type 1 Diabetes Mellitus: Systematic Review. 1型糖尿病儿童患者糖尿病器械的皮肤不良反应:系统综述。
Q3 Medicine Pub Date : 2024-11-07 DOI: 10.2196/59824
Alicia Podwojniak, Joseph Flemming, Isabella J Tan, Hira Ghani, Zachary Neubauer, Anne Jones

Background: Continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusions (CSIIs) are the current standard treatment devices for type 1 diabetes (T1D) management. With a high prevalence of T1D beginning in pediatrics and carrying into adulthood, insufficient glycemic control leads to poor patient outcomes. Dermatologic complications such as contact dermatitis, lipodystrophies, and inflammatory lesions are among those associated with CGM and CSII, which reduce glycemic control and patient compliance.

Objective: This systematic review aims to explore the current literature surrounding dermatologic complications of CGM and CSII as well as the impact on patient outcomes.

Methods: A systematic review of the literature was carried out using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines using 5 online databases. Included articles were those containing primary data relevant to human participants and adverse reactions to CGM and CSII devices in pediatric populations, of which greater than 50% of the sample size were aged 0-21 years. Qualitative analysis was chosen due to the heterogeneity of outcomes.

Results: Following the application of exclusion criteria, 25 studies were analyzed and discussed. An additional 5 studies were identified after the initial search and inclusion. The most common complication covered is contact dermatitis, with 13 identified studies. Further, 7 studies concerned lipodystrophies, 5 covered nonspecific cutaneous changes, 3 covered unique cutaneous findings such as granulomatous reactions and panniculitis, and 2 discussed user acceptability.

Conclusions: The dermatologic complications of CGM and CSII pose a potential risk to long-term glycemic control in T1D, especially in young patients where skin lesions can lead to discontinuation. Increased manufacturer transparency is critical and further studies are needed to expand upon the current preventative measures such as device site rotation and steroid creams, which lack consistent effectiveness.

背景:持续血糖监测(CGM)和持续皮下胰岛素输注(CSIIs)是目前1型糖尿病(T1D)管理的标准治疗手段。由于T1D的高患病率始于儿科并持续到成年,血糖控制不足导致患者预后不良。皮肤并发症,如接触性皮炎、脂肪营养不良和炎性病变是与CGM和CSII相关的,它们降低了血糖控制和患者的依从性。目的:本系统综述旨在探讨目前有关CGM和CSII的皮肤并发症及其对患者预后的影响。方法:使用5个在线数据库,使用PRISMA(首选报告项目用于系统评价和荟萃分析)2020指南对文献进行系统评价。纳入的文章包括那些包含与人类参与者和儿童人群中CGM和CSII装置不良反应相关的主要数据的文章,其中超过50%的样本量为0-21岁。由于结果的异质性,我们选择了定性分析。结果:按照排除标准的应用,对25项研究进行了分析和讨论。在最初的搜索和纳入后,又确定了另外5项研究。最常见的并发症是接触性皮炎,有13项已确定的研究。此外,7项研究涉及脂肪营养不良,5项研究涉及非特异性皮肤变化,3项研究涉及独特的皮肤表现,如肉芽肿反应和全身炎,2项研究讨论用户可接受性。结论:CGM和CSII的皮肤并发症对T1D患者的长期血糖控制构成潜在风险,特别是在皮肤病变可能导致停药的年轻患者中。增加制造商的透明度是至关重要的,需要进一步的研究来扩大目前的预防措施,如器械位置轮换和类固醇乳膏,这些措施缺乏一致的有效性。
{"title":"Cutaneous Adverse Effects From Diabetes Devices in Pediatric Patients With Type 1 Diabetes Mellitus: Systematic Review.","authors":"Alicia Podwojniak, Joseph Flemming, Isabella J Tan, Hira Ghani, Zachary Neubauer, Anne Jones","doi":"10.2196/59824","DOIUrl":"https://doi.org/10.2196/59824","url":null,"abstract":"<p><strong>Background: </strong>Continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusions (CSIIs) are the current standard treatment devices for type 1 diabetes (T1D) management. With a high prevalence of T1D beginning in pediatrics and carrying into adulthood, insufficient glycemic control leads to poor patient outcomes. Dermatologic complications such as contact dermatitis, lipodystrophies, and inflammatory lesions are among those associated with CGM and CSII, which reduce glycemic control and patient compliance.</p><p><strong>Objective: </strong>This systematic review aims to explore the current literature surrounding dermatologic complications of CGM and CSII as well as the impact on patient outcomes.</p><p><strong>Methods: </strong>A systematic review of the literature was carried out using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 guidelines using 5 online databases. Included articles were those containing primary data relevant to human participants and adverse reactions to CGM and CSII devices in pediatric populations, of which greater than 50% of the sample size were aged 0-21 years. Qualitative analysis was chosen due to the heterogeneity of outcomes.</p><p><strong>Results: </strong>Following the application of exclusion criteria, 25 studies were analyzed and discussed. An additional 5 studies were identified after the initial search and inclusion. The most common complication covered is contact dermatitis, with 13 identified studies. Further, 7 studies concerned lipodystrophies, 5 covered nonspecific cutaneous changes, 3 covered unique cutaneous findings such as granulomatous reactions and panniculitis, and 2 discussed user acceptability.</p><p><strong>Conclusions: </strong>The dermatologic complications of CGM and CSII pose a potential risk to long-term glycemic control in T1D, especially in young patients where skin lesions can lead to discontinuation. Increased manufacturer transparency is critical and further studies are needed to expand upon the current preventative measures such as device site rotation and steroid creams, which lack consistent effectiveness.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e59824"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett's Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends. 吉米-巴菲特(Jimmy Buffett)去世后美国公众对梅克尔细胞癌的兴趣及其对持续健康宣传的影响:谷歌趋势信息学研究。
Q3 Medicine Pub Date : 2024-10-31 DOI: 10.2196/60282
Macy Haight, Hayden R Jacobs, Sarah K Boltey, Kelly A Murray, Micah Hartwell

Unlabelled: Through Jimmy Buffett's unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as evidenced by our results.

无标签:吉米-巴菲特不幸罹患梅克尔细胞癌引发的淋巴瘤,随后媒体对他的死进行了报道,公众对皮肤癌、梅克尔细胞癌以及阳光照射对健康的影响的兴趣也随之增加,我们的研究结果就是明证。
{"title":"US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett's Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends.","authors":"Macy Haight, Hayden R Jacobs, Sarah K Boltey, Kelly A Murray, Micah Hartwell","doi":"10.2196/60282","DOIUrl":"10.2196/60282","url":null,"abstract":"<p><strong>Unlabelled: </strong>Through Jimmy Buffett's unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as evidenced by our results.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e60282"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11542905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Popular Skin-of-Color Dermatology Social Media Hashtags on TikTok From 2021 to 2022: Content Analysis. 2021 年至 2022 年 TikTok 上流行的有色皮肤病社交媒体标签:内容分析。
Q3 Medicine Pub Date : 2024-10-18 DOI: 10.2196/50408
Jeemin Kang, Mindy D Szeto, Lois Suh, Jadesola T Olayinka, Robert P Dellavalle

Unlabelled: TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color-related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.

无标签TikTok 是一个可以向用户传授皮肤病知识的社交媒体平台,但这项对 2021 年至 2022 年与有色人种皮肤相关的 TikTok 标签进行的纵向分析表明,非皮肤科医生的影响者继续主导着内容创作,这凸显出需要更多经过委员会认证的皮肤科医生的参与,以积极抵制错误信息,解决有色人种皮肤医疗保健中的潜在差异。
{"title":"Popular Skin-of-Color Dermatology Social Media Hashtags on TikTok From 2021 to 2022: Content Analysis.","authors":"Jeemin Kang, Mindy D Szeto, Lois Suh, Jadesola T Olayinka, Robert P Dellavalle","doi":"10.2196/50408","DOIUrl":"10.2196/50408","url":null,"abstract":"<p><strong>Unlabelled: </strong>TikTok is a social media platform that can educate users about dermatology, but this longitudinal analysis of skin of color-related TikTok hashtags from 2021 to 2022 suggests that nondermatologist influencers continue to dominate content creation, highlighting the need for more participation from board-certified dermatologists to actively counter misinformation and address potential disparities in skin-of-color health care.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e50408"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11506142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in Teledermoscopy Diagnostic Outcome Studies: Scoping Review of Heterogeneous Study Characteristics. 远程皮肤镜诊断结果研究的挑战:对异质研究特征的范围审查。
Q3 Medicine Pub Date : 2024-10-18 DOI: 10.2196/60346
Femke van Sinderen, Anne P Langermans, Andre W Kushniruk, Elizabeth M Borycki, Monique M Jaspers, Linda W Peute
<p><strong>Background: </strong>Teledermoscopy has demonstrated benefits such as decreased costs and enhanced access to dermatology care for skin cancer detection. However, the heterogeneity among teledermoscopy studies hinders the systematic reviews' synopsis of diagnostic outcomes, impeding trust and adoption in general practice and limiting overall health care benefits.</p><p><strong>Objective: </strong>This study aims to improve understanding and standardization of teledermoscopy diagnostic studies, by identifying and categorizing study characteristics contributing to heterogeneity. Subsequently, the variability and consistency of these characteristics were assessed.</p><p><strong>Methods: </strong>A review of systematic reviews regarding the diagnostic outcomes of teledermoscopy was performed to discern reported study characteristics contributing to heterogeneity. These characteristics were thematically grouped into 3 domains (population, index test, and reference standard), forming a data extraction framework. A scoping review on teledermoscopy diagnostic outcomes studies was performed, guided by the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. Data pertaining to study characteristics from included studies were extracted and analyzed through descriptive content analysis. Systematic reviews' reference lists validated the scoping review query.</p><p><strong>Results: </strong>The literature search yielded 4 systematic reviews, revealing 15 heterogeneous studies across the population, index test, and reference standard domains. The scoping review identified 49 studies, with 27 overlapping with the systematic reviews. Population characteristics varied, with one-third (16/49, 33%) of studies reporting fewer than 100 samples; most studies (41/49, 84%) reported on the type of lesion, and most (20/49, 41%) teledermoscopy consultations took place in secondary care. One-fifth (11/49, 22%) did not describe inclusion or exclusion criteria, or the criteria varied highly. Index test characteristics showed differences in clinical expertise, profession, and training in dermatoscopic photography, and 59% (29/49) did not report on 1 or more index test characteristics. Image quality and clinical information reporting likewise varied. Reference standard characteristics involved teledermatologists' assessment, but 16 studies did not report teledermatologists' experience levels. Most studies (26/49, 53%) used histopathology as a gold standard.</p><p><strong>Conclusions: </strong>The heterogeneity in the population, index tests, and reference standard domains across teledermoscopy diagnostic outcome studies underscores the need for standardized reporting. This hinders the synopsis of teledermoscopy diagnostic outcomes in systematic reviews and limits the integration of research results into practice. Adopting a (tailored) STARD (Standards for Reporting Diagnostic Accuracy Studies) checklis
背景:远程皮肤镜已被证明可降低皮肤癌检测的成本并提高皮肤病治疗的可及性。然而,远程皮肤镜研究之间的异质性阻碍了系统综述对诊断结果的概括,妨碍了普通实践中对远程皮肤镜的信任和采用,限制了整体医疗保健效益:本研究旨在通过对导致异质性的研究特征进行识别和分类,提高对远程皮肤镜诊断研究的理解和标准化。随后,对这些特征的可变性和一致性进行了评估:方法:我们对有关远程皮肤镜检查诊断结果的系统综述进行了回顾,以找出导致异质性的已报道研究特征。这些特征按主题分为3个领域(人群、指标检测和参考标准),形成了一个数据提取框架。在PRISMA-ScR(系统性综述和荟萃分析的首选报告项目扩展范围综述)核对表的指导下,对远程皮肤镜诊断结果研究进行了范围综述。通过描述性内容分析法提取并分析了纳入研究中与研究特征相关的数据。系统综述的参考文献列表验证了范围界定综述的查询结果:文献检索共获得 4 篇系统综述,发现了 15 项涉及人群、指标测试和参考标准领域的不同研究。范围界定审查确定了 49 项研究,其中 27 项与系统综述重叠。研究人群的特征各不相同,三分之一(16/49,33%)的研究报告了少于 100 个样本;大多数研究(41/49,84%)报告了病变类型,大多数(20/49,41%)远程皮肤镜检查是在二级医疗机构进行的。五分之一的研究(11/49,22%)没有说明纳入或排除标准,或者标准差异很大。指标检测特征显示了临床专业知识、专业和皮肤镜摄影培训方面的差异,59%(29/49)没有报告一项或多项指标检测特征。图像质量和临床信息报告同样存在差异。参考标准特征涉及远程皮肤科医生的评估,但有 16 项研究未报告远程皮肤科医生的经验水平。大多数研究(26/49,53%)将组织病理学作为金标准:结论:远程皮肤镜诊断结果研究在人群、指标测试和参考标准领域的异质性强调了标准化报告的必要性。这阻碍了系统综述中对皮肤远程镜检查诊断结果的概括,并限制了将研究结果融入实践。建议采用(量身定制的)STARD(诊断准确性研究报告标准)核对表来进行远程皮肤镜诊断结果研究,以提高结果的一致性和可比性。我们建议开展德尔菲研究,就量身定制的 STARD 指南达成共识。
{"title":"Challenges in Teledermoscopy Diagnostic Outcome Studies: Scoping Review of Heterogeneous Study Characteristics.","authors":"Femke van Sinderen, Anne P Langermans, Andre W Kushniruk, Elizabeth M Borycki, Monique M Jaspers, Linda W Peute","doi":"10.2196/60346","DOIUrl":"10.2196/60346","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Teledermoscopy has demonstrated benefits such as decreased costs and enhanced access to dermatology care for skin cancer detection. However, the heterogeneity among teledermoscopy studies hinders the systematic reviews' synopsis of diagnostic outcomes, impeding trust and adoption in general practice and limiting overall health care benefits.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to improve understanding and standardization of teledermoscopy diagnostic studies, by identifying and categorizing study characteristics contributing to heterogeneity. Subsequently, the variability and consistency of these characteristics were assessed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A review of systematic reviews regarding the diagnostic outcomes of teledermoscopy was performed to discern reported study characteristics contributing to heterogeneity. These characteristics were thematically grouped into 3 domains (population, index test, and reference standard), forming a data extraction framework. A scoping review on teledermoscopy diagnostic outcomes studies was performed, guided by the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist. Data pertaining to study characteristics from included studies were extracted and analyzed through descriptive content analysis. Systematic reviews' reference lists validated the scoping review query.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The literature search yielded 4 systematic reviews, revealing 15 heterogeneous studies across the population, index test, and reference standard domains. The scoping review identified 49 studies, with 27 overlapping with the systematic reviews. Population characteristics varied, with one-third (16/49, 33%) of studies reporting fewer than 100 samples; most studies (41/49, 84%) reported on the type of lesion, and most (20/49, 41%) teledermoscopy consultations took place in secondary care. One-fifth (11/49, 22%) did not describe inclusion or exclusion criteria, or the criteria varied highly. Index test characteristics showed differences in clinical expertise, profession, and training in dermatoscopic photography, and 59% (29/49) did not report on 1 or more index test characteristics. Image quality and clinical information reporting likewise varied. Reference standard characteristics involved teledermatologists' assessment, but 16 studies did not report teledermatologists' experience levels. Most studies (26/49, 53%) used histopathology as a gold standard.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The heterogeneity in the population, index tests, and reference standard domains across teledermoscopy diagnostic outcome studies underscores the need for standardized reporting. This hinders the synopsis of teledermoscopy diagnostic outcomes in systematic reviews and limits the integration of research results into practice. Adopting a (tailored) STARD (Standards for Reporting Diagnostic Accuracy Studies) checklis","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e60346"},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Participant Motivators and Expectations in the MEL-SELF Randomized Clinical Trial of Patient-Led Surveillance for Recurrent Melanoma: Content Analysis of Survey Responses. 患者主导的复发性黑色素瘤监测 MEL-SELF 随机临床试验的参与者动机和期望:调查回复内容分析。
Q3 Medicine Pub Date : 2024-10-17 DOI: 10.2196/58136
Deonna Ackermann, Jolyn Hersch, Dana Jordan, Emily Clinton-Gray, Karen Bracken, Monika Janda, Robin Turner, Katy Bell
<p><strong>Background: </strong>Limited data exist on the motivations and expectations of participants when enrolling in dermatology clinical trials, including melanoma early detection trials. Understanding participant motivators for research engagement has been identified as a prioritized area for trial methodology research.</p><p><strong>Objective: </strong>The study aimed to determine motivators of participation and expectations from trial involvement among patients enrolled in the MEL-SELF randomized clinical trial of patient-led surveillance for new or recurrent melanoma.</p><p><strong>Methods: </strong>The MEL-SELF trial is recruiting patients previously treated for localized melanoma, who own a smartphone, have a partner to assist with skin self-examination (SSE), and attend routinely scheduled follow-up at specialist and primary care skin clinics in Australia. We evaluated responses from the first 100 randomized participants to 2 open-ended questions about their motivations and expectations for participating in the trial, administered through the internet-based baseline questionnaire. A total of 3 coders independently coded the free-text responses and resolved discrepancies through consensus. Qualitative content analysis by an iterative process was used to group responses into themes. Responses from potential participants who were not randomized and the 404 participants randomized subsequently into the trial, were also checked for new themes. Coding and analysis were conducted in Microsoft Excel.</p><p><strong>Results: </strong>Out of the 100 survey participants, 98 (98%) answered at least 1 of the 2 questions. Overall, responses across the motivation and expectation items indicated 3 broad themes: community benefit, perceived personal benefit, and trusting relationship with their health care provider. The most common motivators for participation were related to community benefit. These included progressing medical research, benefitting future melanoma patients who may have similar experiences, and broader altruistic sentiments such as "helping others" or "giving back." The most common expectations from the trial related to personal benefit. These included perceived improved outcomes such as earlier diagnosis and treatment, access to additional care, and increased self-empowerment to take actions themselves that benefit their health. Patients expressed a desire to gain health-related knowledge and skills and were interested in the potential advantages of teledermatology. There were no new themes in responses from those who were not randomized or were randomized subsequent to the first 100.</p><p><strong>Conclusions: </strong>We report a tailorable, patient-focused approach to identify drivers of research engagement in clinical research. Clinical trials offer an opportunity to collate a substantial evidence base on determinants of research participation and to identify context-specific factors. Results from the MEL-SELF trial emphasized no
背景:关于参与者参与皮肤科临床试验(包括黑色素瘤早期检测试验)的动机和期望的数据有限。了解参与者参与研究的动机已被确定为试验方法学研究的优先领域:本研究旨在确定参加 MEL-SELF 随机临床试验的患者参与试验的动机以及对参与试验的期望:MEL-SELF试验正在招募曾接受过局部黑色素瘤治疗、拥有智能手机、有伴侣协助进行皮肤自我检查(SSE)并定期到澳大利亚专科和初级皮肤诊所进行随访的患者。我们评估了首批 100 名随机参与者对 2 个开放式问题的回答,这些问题涉及他们参与试验的动机和期望,是通过基于互联网的基线问卷调查进行的。共有 3 位编码员对自由文本回答进行了独立编码,并在达成共识的基础上解决了不一致的问题。通过迭代过程进行定性内容分析,将回答归类为主题。未被随机选中的潜在参与者和随后被随机选中参加试验的 404 名参与者的回答也被检查,以确定新的主题。编码和分析均在 Microsoft Excel 中进行:在 100 名调查参与者中,98 人(98%)至少回答了 2 个问题中的 1 个。总体而言,对动机和期望项目的回答显示出 3 个广泛的主题:社区利益、感知到的个人利益以及与医疗服务提供者之间的信任关系。最常见的参与动机与社区利益有关。其中包括医学研究的进展、造福未来可能有类似经历的黑色素瘤患者,以及更广泛的利他情感,如 "帮助他人 "或 "回馈社会"。最常见的试验期望与个人利益有关。这些期望包括预期的治疗效果改善,如更早诊断和治疗、获得更多护理,以及增强自我能力,采取有利于自身健康的行动。患者表示希望获得与健康相关的知识和技能,并对远程皮肤病学的潜在优势感兴趣。未被随机选中或在第一批 100 名患者之后被随机选中的患者的回答中没有新的主题:我们报告了一种量身定制的、以患者为中心的方法,用于识别临床研究中的研究参与驱动因素。临床试验为整理研究参与决定因素的大量证据基础和识别特定环境因素提供了机会。MEL-SELF试验的结果强调了显著的利他主义、自我赋权和远程皮肤病学的优势。这些研究结果为 MEL-SELF 主试验的同意程序、招募、保留、对试验任务的反应以及坚持干预提供了信息:试验注册:澳大利亚-新西兰临床试验注册中心(ANZCTR):ACTRN12621000176864。https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379527。
{"title":"Participant Motivators and Expectations in the MEL-SELF Randomized Clinical Trial of Patient-Led Surveillance for Recurrent Melanoma: Content Analysis of Survey Responses.","authors":"Deonna Ackermann, Jolyn Hersch, Dana Jordan, Emily Clinton-Gray, Karen Bracken, Monika Janda, Robin Turner, Katy Bell","doi":"10.2196/58136","DOIUrl":"10.2196/58136","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Limited data exist on the motivations and expectations of participants when enrolling in dermatology clinical trials, including melanoma early detection trials. Understanding participant motivators for research engagement has been identified as a prioritized area for trial methodology research.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The study aimed to determine motivators of participation and expectations from trial involvement among patients enrolled in the MEL-SELF randomized clinical trial of patient-led surveillance for new or recurrent melanoma.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The MEL-SELF trial is recruiting patients previously treated for localized melanoma, who own a smartphone, have a partner to assist with skin self-examination (SSE), and attend routinely scheduled follow-up at specialist and primary care skin clinics in Australia. We evaluated responses from the first 100 randomized participants to 2 open-ended questions about their motivations and expectations for participating in the trial, administered through the internet-based baseline questionnaire. A total of 3 coders independently coded the free-text responses and resolved discrepancies through consensus. Qualitative content analysis by an iterative process was used to group responses into themes. Responses from potential participants who were not randomized and the 404 participants randomized subsequently into the trial, were also checked for new themes. Coding and analysis were conducted in Microsoft Excel.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of the 100 survey participants, 98 (98%) answered at least 1 of the 2 questions. Overall, responses across the motivation and expectation items indicated 3 broad themes: community benefit, perceived personal benefit, and trusting relationship with their health care provider. The most common motivators for participation were related to community benefit. These included progressing medical research, benefitting future melanoma patients who may have similar experiences, and broader altruistic sentiments such as \"helping others\" or \"giving back.\" The most common expectations from the trial related to personal benefit. These included perceived improved outcomes such as earlier diagnosis and treatment, access to additional care, and increased self-empowerment to take actions themselves that benefit their health. Patients expressed a desire to gain health-related knowledge and skills and were interested in the potential advantages of teledermatology. There were no new themes in responses from those who were not randomized or were randomized subsequent to the first 100.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;We report a tailorable, patient-focused approach to identify drivers of research engagement in clinical research. Clinical trials offer an opportunity to collate a substantial evidence base on determinants of research participation and to identify context-specific factors. Results from the MEL-SELF trial emphasized no","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e58136"},"PeriodicalIF":0.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11528161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI in Psoriatic Disease: Scoping Review. 银屑病中的人工智能:范围界定综述
Q3 Medicine Pub Date : 2024-10-16 DOI: 10.2196/50451
Richard Barlow, Anthony Bewley, Maria Angeliki Gkini

Background: Artificial intelligence (AI) has many applications in numerous medical fields, including dermatology. Although the majority of AI studies in dermatology focus on skin cancer, there is growing interest in the applicability of AI models in inflammatory diseases, such as psoriasis. Psoriatic disease is a chronic, inflammatory, immune-mediated systemic condition with multiple comorbidities and a significant impact on patients' quality of life. Advanced treatments, including biologics and small molecules, have transformed the management of psoriatic disease. Nevertheless, there are still considerable unmet needs. Globally, delays in the diagnosis of the disease and its severity are common due to poor access to health care systems. Moreover, despite the abundance of treatments, we are unable to predict which is the right medication for the right patient, especially in resource-limited settings. AI could be an additional tool to address those needs. In this way, we can improve rates of diagnosis, accurately assess severity, and predict outcomes of treatment.

Objective: This study aims to provide an up-to-date literature review on the use of AI in psoriatic disease, including diagnostics and clinical management as well as addressing the limitations in applicability.

Methods: We searched the databases MEDLINE, PubMed, and Embase using the keywords "AI AND psoriasis OR psoriatic arthritis OR psoriatic disease," "machine learning AND psoriasis OR psoriatic arthritis OR psoriatic disease," and "prognostic model AND psoriasis OR psoriatic arthritis OR psoriatic disease" until June 1, 2023. Reference lists of relevant papers were also cross-examined for other papers not detected in the initial search.

Results: Our literature search yielded 38 relevant papers. AI has been identified as a key component in digital health technologies. Within this field, there is the potential to apply specific techniques such as machine learning and deep learning to address several aspects of managing psoriatic disease. This includes diagnosis, particularly useful for remote teledermatology via photographs taken by patients as well as monitoring and estimating severity. Similarly, AI can be used to synthesize the vast data sets already in place through patient registries which can help identify appropriate biologic treatments for future cohorts and those individuals most likely to develop complications.

Conclusions: There are multiple advantageous uses for AI and digital health technologies in psoriatic disease. With wider implementation of AI, we need to be mindful of potential limitations, such as validation and standardization or generalizability of results in specific populations, such as patients with darker skin phototypes.

背景:人工智能(AI)在许多医学领域都有广泛应用,包括皮肤病学。虽然皮肤病学领域的大多数人工智能研究都集中在皮肤癌方面,但人们对人工智能模型在银屑病等炎症性疾病中的适用性的兴趣也在不断增长。银屑病是一种慢性、炎症性、免疫介导的全身性疾病,具有多种并发症,对患者的生活质量有很大影响。包括生物制剂和小分子药物在内的先进疗法已经改变了银屑病的治疗方法。然而,仍有大量需求尚未得到满足。在全球范围内,由于医疗体系不完善,延误疾病诊断及其严重程度的现象十分普遍。此外,尽管治疗方法很多,但我们无法预测哪种药物适合合适的患者,尤其是在资源有限的环境中。人工智能可以成为满足这些需求的额外工具。这样,我们就能提高诊断率、准确评估严重程度并预测治疗结果:本研究旨在提供有关人工智能在银屑病中应用的最新文献综述,包括诊断和临床管理,以及解决适用性方面的局限性:我们使用关键词 "人工智能和银屑病或银屑病关节炎或银屑病"、"机器学习和银屑病或银屑病关节炎或银屑病 "以及 "预后模型和银屑病或银屑病关节炎或银屑病 "检索了 MEDLINE、PubMed 和 Embase 等数据库,检索期至 2023 年 6 月 1 日。我们还对相关论文的参考文献列表进行了交叉检索,以查找初次检索未发现的其他论文:结果:通过文献检索,我们找到了 38 篇相关论文。人工智能已被确定为数字医疗技术的关键组成部分。在这一领域,有可能应用机器学习和深度学习等特定技术来解决银屑病管理的几个方面。这包括诊断,尤其是通过患者拍摄的照片进行远程皮肤科诊断,以及监测和估计严重程度。同样,人工智能还可用于综合患者登记处已有的大量数据集,这有助于为未来的群体和最有可能出现并发症的个人确定适当的生物治疗方法:人工智能和数字医疗技术在银屑病中的应用具有多种优势。随着人工智能的广泛应用,我们需要注意其潜在的局限性,如特定人群(如深肤色患者)的验证和标准化或结果的普遍性。
{"title":"AI in Psoriatic Disease: Scoping Review.","authors":"Richard Barlow, Anthony Bewley, Maria Angeliki Gkini","doi":"10.2196/50451","DOIUrl":"10.2196/50451","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) has many applications in numerous medical fields, including dermatology. Although the majority of AI studies in dermatology focus on skin cancer, there is growing interest in the applicability of AI models in inflammatory diseases, such as psoriasis. Psoriatic disease is a chronic, inflammatory, immune-mediated systemic condition with multiple comorbidities and a significant impact on patients' quality of life. Advanced treatments, including biologics and small molecules, have transformed the management of psoriatic disease. Nevertheless, there are still considerable unmet needs. Globally, delays in the diagnosis of the disease and its severity are common due to poor access to health care systems. Moreover, despite the abundance of treatments, we are unable to predict which is the right medication for the right patient, especially in resource-limited settings. AI could be an additional tool to address those needs. In this way, we can improve rates of diagnosis, accurately assess severity, and predict outcomes of treatment.</p><p><strong>Objective: </strong>This study aims to provide an up-to-date literature review on the use of AI in psoriatic disease, including diagnostics and clinical management as well as addressing the limitations in applicability.</p><p><strong>Methods: </strong>We searched the databases MEDLINE, PubMed, and Embase using the keywords \"AI AND psoriasis OR psoriatic arthritis OR psoriatic disease,\" \"machine learning AND psoriasis OR psoriatic arthritis OR psoriatic disease,\" and \"prognostic model AND psoriasis OR psoriatic arthritis OR psoriatic disease\" until June 1, 2023. Reference lists of relevant papers were also cross-examined for other papers not detected in the initial search.</p><p><strong>Results: </strong>Our literature search yielded 38 relevant papers. AI has been identified as a key component in digital health technologies. Within this field, there is the potential to apply specific techniques such as machine learning and deep learning to address several aspects of managing psoriatic disease. This includes diagnosis, particularly useful for remote teledermatology via photographs taken by patients as well as monitoring and estimating severity. Similarly, AI can be used to synthesize the vast data sets already in place through patient registries which can help identify appropriate biologic treatments for future cohorts and those individuals most likely to develop complications.</p><p><strong>Conclusions: </strong>There are multiple advantageous uses for AI and digital health technologies in psoriatic disease. With wider implementation of AI, we need to be mindful of potential limitations, such as validation and standardization or generalizability of results in specific populations, such as patients with darker skin phototypes.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e50451"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender Representation in Authorship of Academic Dermatology Publications During the COVID-19 Pandemic: Cross-Sectional Study. COVID-19大流行期间皮肤科学术论文作者中的性别比例:横断面研究。
Q3 Medicine Pub Date : 2024-10-16 DOI: 10.2196/50396
Mindy D Szeto, Melissa R Laughter, Mayra B C Maymone, Payal M Patel, Torunn E Sivesind, Colby L Presley, Steven M Lada, Kayd J Pulsipher, Henriette De La Garza, Robert P Dellavalle

Unlabelled: Analyses of women dermatology literature authorship from 2018 to 2022 reveal a slight increase in total female authors, female first authors, and female senior authors with no substantial immediate impact of COVID-19 on current trends, encouraging future examination of long-term effects and ongoing promotion of systemic initiatives to support gender equity.

无标签:对 2018 年至 2022 年女性皮肤病学文献作者的分析显示,女性作者总数、女性第一作者和女性资深作者人数略有增加,COVID-19 对当前趋势没有产生实质性的直接影响,鼓励未来对长期影响进行研究,并持续推动支持性别平等的系统性举措。
{"title":"Gender Representation in Authorship of Academic Dermatology Publications During the COVID-19 Pandemic: Cross-Sectional Study.","authors":"Mindy D Szeto, Melissa R Laughter, Mayra B C Maymone, Payal M Patel, Torunn E Sivesind, Colby L Presley, Steven M Lada, Kayd J Pulsipher, Henriette De La Garza, Robert P Dellavalle","doi":"10.2196/50396","DOIUrl":"10.2196/50396","url":null,"abstract":"<p><strong>Unlabelled: </strong>Analyses of women dermatology literature authorship from 2018 to 2022 reveal a slight increase in total female authors, female first authors, and female senior authors with no substantial immediate impact of COVID-19 on current trends, encouraging future examination of long-term effects and ongoing promotion of systemic initiatives to support gender equity.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"7 ","pages":"e50396"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
JMIR dermatology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1