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Utilizing the VISIA Camera for Analyzing 5-Fluorouracil Treatment Efficacy for Actinic Keratosis. 应用VISIA相机分析5-氟尿嘧啶治疗光化性角化病的疗效。
Q3 Medicine Pub Date : 2025-12-19 DOI: 10.2196/66553
Emily Woolhiser, Leena Jamal, Jessica Kirk, Bertha Baum, Robert Dellavalle

Unlabelled: The VISIA camera is a device that captures images of the skin, offering a detailed look at skin health by detecting changes that are often missed during physical exams and by the naked eye. It can help identify changes in UV damage, pigmentation, texture, fine lines, and redness. In dermatology, it has become a useful tool to build targeted treatment plans and follow patient progress over time. We present a case of a male patient diagnosed with diffuse scalp actinic keratoses who was treated with topical 5-fluorouracil (5-FU). VISIA images were taken before treatment, at one week, and again three months following therapy. The images were reviewed for changes in UV spots, texture, and other generalized spots. Results revealed a decrease in UV spots, a temporary improvement in texture followed by a later rise, and no significant change in generalized spots. This case highlights the value of VISIA imaging as an objective method for assessing treatment response and evaluating the effectiveness of 5-FU in the management of actinic keratoses.

无标签:VISIA相机是一种捕捉皮肤图像的设备,通过检测在体检和肉眼中经常遗漏的变化,提供详细的皮肤健康状况。它可以帮助识别紫外线损伤、色素沉着、纹理、细纹和发红的变化。在皮肤科,它已成为一个有用的工具,以建立有针对性的治疗计划和跟踪病人的进展。我们提出一个病例的男性患者诊断为弥漫性头皮光化性角化病谁是治疗外用5-氟尿嘧啶(5-FU)。在治疗前、治疗后一周和治疗后三个月分别拍摄VISIA图像。对图像进行了审查,以了解紫外线斑点,纹理和其他广义斑点的变化。结果显示,紫外线斑减少,纹理暂时改善,随后上升,而广泛性斑没有明显变化。本病例强调了VISIA成像作为评估治疗反应和评估5-FU治疗光化性角化病有效性的客观方法的价值。
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引用次数: 0
3D Total Body Photography as a Promising Innovation for Early Skin Cancer Detection: Scoping Review. 3D全身摄影作为早期皮肤癌检测的有前途的创新:范围审查。
Q3 Medicine Pub Date : 2025-12-17 DOI: 10.2196/68510
Fran Baete, Alyssa Laura Jakers, Emilie Delanoye, Nele Vande Velde, Griet Voet
<p><strong>Background: </strong>Skin cancer (SC) is a global health concern because of its high and still increasing incidence and associated health care cost. Belgium is no exception as 1 in 5 people are diagnosed with SC before the age of 75 years. The VECTRA WB360, a 3D total body photography system, allows clinicians to objectively compare the totality of the skin on a macroscopic level on further appointments. The integrated lesion visualization software allows automated detection, counts, and assessment of skin lesions. Detailed comparison of individual lesions is possible through the attached digital dermatoscope.</p><p><strong>Objective: </strong>This study aims to review available literature on the use of the VECTRA in research and clinical settings and to summarize the clinical utility, advantages, and limitations reported for this system.</p><p><strong>Methods: </strong>An electronic literature search was conducted on PubMed from December 2023 to March 2024 using a combination of the following search terms: 3D imaging, VECTRA WB360, melanoma, nonmelanoma skin cancer, their synonyms, and associated entry terms. Publications that used a device other than the VECTRA WB360 were excluded, as were papers reporting on new technology without further research or without added cases. After a thorough screening of the papers and removal of duplicates, 11 papers remained.</p><p><strong>Results: </strong>Our literature search yielded 11 relevant papers, which included 2 case studies, 6 prospective studies, and 3 retrospective studies. According to multiple studies, the VECTRA WB360 images were of a high enough quality to allow on-screen diagnosis of some melanoma and nonmelanoma skin cancers by dermatologists. Sensitivity compared to face-to-face examination for melanoma is unknown. The integrated lesion visualization software is capable of detecting and counting naevi and distinguishing melanoma from other skin lesions with high accuracy, with convolutional neural network integration further enhancing its sensitivity and specificity. However, it is important to note that no comparison to the usual standard of care was made. Also, dermatologists achieved greater specificity and thus remained superior to machine and artificial intelligence (AI).</p><p><strong>Conclusions: </strong>Although the VECTRA 3D TBP holds substantial promise for the early detection and monitoring of SC, its application cannot yet replace the expertise of trained clinicians. Although the lesion visualizer and dermoscopy explainable intelligence (DEXI) score offer potential enhancements, they also pose risks, including a significant increase in unnecessary excisions due to lower specificity. Expert overview is still recommended and superior, since there is not enough evidence yet that 3D TBP or AI is reliable on its own or beneficial as a support tool. Given the small samples and lack of blinded trials, further studies are needed to explore and improve the diagnostic capacitie
背景:皮肤癌(SC)是一个全球性的健康问题,因为它的高发病率和相关的卫生保健费用仍在增加。比利时也不例外,五分之一的人在75岁之前被诊断为SC。VECTRA WB360是一种3D全身摄影系统,允许临床医生在进一步的预约中客观地比较皮肤的宏观水平。集成的病变可视化软件允许自动检测、计数和评估皮肤病变。通过所附的数字皮肤镜可以对个别病变进行详细的比较。目的:本研究旨在回顾有关VECTRA在研究和临床中使用的现有文献,并总结该系统的临床应用、优势和局限性。方法:从2023年12月到2024年3月,使用以下搜索词组合在PubMed上进行电子文献检索:3D成像、VECTRA WB360、黑色素瘤、非黑色素瘤皮肤癌、其同义词和相关词条。使用VECTRA WB360以外设备的出版物被排除在外,没有进一步研究或没有增加病例的新技术报告也被排除在外。在对文件进行彻底的筛选和删除重复文件后,留下了11份文件。结果:检索到相关文献11篇,其中2篇为个案研究,6篇为前瞻性研究,3篇为回顾性研究。根据多项研究,VECTRA WB360图像的质量足够高,皮肤科医生可以在屏幕上诊断一些黑色素瘤和非黑色素瘤皮肤癌。与面对面检查相比,对黑色素瘤的敏感性尚不清楚。集成病变可视化软件能够对痣进行检测和计数,并能够高精度地将黑色素瘤与其他皮肤病变区分开来,卷积神经网络的融合进一步提高了其敏感性和特异性。然而,重要的是要注意,没有与通常的护理标准进行比较。此外,皮肤科医生获得了更大的特异性,因此仍然优于机器和人工智能(AI)。结论:尽管VECTRA 3D TBP在SC的早期发现和监测方面有很大的前景,但它的应用还不能取代训练有素的临床医生的专业知识。尽管病变显像仪和皮肤镜可解释智力(DEXI)评分提供了潜在的增强功能,但它们也存在风险,包括由于特异性较低而导致不必要的手术显著增加。专家概述仍然是推荐和优先考虑的,因为目前还没有足够的证据表明3D TBP或AI本身是可靠的,或者作为辅助工具是有益的。鉴于样本量小且缺乏盲法试验,需要进一步的研究来探索和提高3D TBP的诊断能力,以及可能整合cnn或其他人工智能扩展,并将VECTRA 360WB与通常的护理标准进行比较。
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引用次数: 0
Image Generation of Common Dermatological Diagnoses by Artificial Intelligence: Evaluation Study of the Potential for Education and Training Purposes. 用人工智能生成常见皮肤病诊断的图像:教育和培训潜力的评估研究。
Q3 Medicine Pub Date : 2025-12-16 DOI: 10.2196/72371
Sarah Kooper-Johnson, Subin Lim, Jumana Aldhalaan, Gabriela Cobos, Vijay Kodumudi, Daniel S Loo, Joshua Mervis, Madalyn Petrillo, Sarah N Robinson, Bichchau Michelle Nguyen

Background: The integration of artificial intelligence (AI) into dermatology holds promise for education and diagnostic purposes, particularly through image generation, which has not been well studied.

Objective: This study aimed to assess whether AI image generation software can generate accurate images of classic dermatological conditions and whether they are recognizable as computer-generated.

Methods: Images of 10 dermatological conditions were generated using DALLE-2 and DALLE-3 programs. These images were randomized among clinical photographs and distributed to dermatology residents and attending physicians. Participants were instructed to (1) identify AI-generated images and (2) provide their diagnosis.

Results: AI-generated images were detected as computer-generated in 70.8% (85/120) of cases. Correct diagnoses were made based on all AI images 40.83% (49/120) of the time. This was significantly lower than the 72.0% (46/60) recognition rate for clinical photographs (P<.001). DALLE-2 images were diagnosed correctly less frequently (25.0%, 15/60) than DALLE-3 images (56.6%, 34/60; P<.001).

Conclusions: AI-generated images of common dermatological conditions are becoming more accurate. This holds great implications for education but should be used with caution as further research is needed with more advanced, specific, and inclusive training data. Limitations include the use of AI image generators created by a single parent company as well as the use of a limited set of diagnoses.

背景:人工智能(AI)与皮肤病学的整合为教育和诊断目的带来了希望,特别是通过图像生成,这还没有得到很好的研究。目的:本研究旨在评估人工智能图像生成软件是否可以生成准确的经典皮肤病图像,以及它们是否可识别为计算机生成的图像。方法:采用dale -2和dale -3程序生成10种皮肤病的图像。这些图像在临床照片中随机分配给皮肤科住院医师和主治医生。参与者被要求(1)识别人工智能生成的图像,(2)提供他们的诊断。结果:70.8%(85/120)的病例将人工智能生成的图像检测为计算机生成的图像。所有AI图像的诊断正确率为40.83%(49/120)。这明显低于临床照片的72.0%(46/60)识别率。结论:人工智能生成的常见皮肤病图像正变得越来越准确。这对教育具有重大意义,但应谨慎使用,因为需要进一步研究更先进、更具体、更包容的培训数据。限制包括使用由单一母公司创建的人工智能图像生成器以及使用有限的诊断集。
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引用次数: 0
Trends in Synchronous Teledermatology Use by Level of Service Among Medicare Beneficiaries From 2017 to 2023: Retrospective Observational Study. 2017年至2023年医疗保险受益人按服务水平分类的同步远程皮肤科使用趋势:回顾性观察研究
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.2196/78438
Vincent Le, Carina Shiau, Arash Pour Mohammad, Vivian Yang, Gordon Hyeonjin Bae

Unlabelled: This retrospective observational study was conducted to evaluate trends in synchronous teledermatology use across different levels of clinical complexity among Medicare beneficiaries, analyzing data from the Medicare Part B Physician/Supplier Procedure Summary Master Files; we founding that the growing use of teledermatology for complex visits highlights its potential as a long-term approach for improving dermatologic care.

未标记:这项回顾性观察性研究旨在评估医疗保险受益人在不同临床复杂程度下同步远程皮肤科使用的趋势,分析来自医疗保险B部分医生/供应商程序摘要主文件的数据;我们发现,越来越多的使用远程皮肤科复杂的访问突出了其潜力,作为一个长期的方法,以改善皮肤科护理。
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引用次数: 0
The Role of TikTok on the Education of Hidradenitis Suppurativa in Skin of Color: A Cross-Sectional Analysis. TikTok在有色皮肤化脓性汗腺炎教育中的作用:横断面分析。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.2196/71566
Arsema K Zadu, Jordan Young, Janyla A Seltzer, Angel S Byrd, Cheri Frey

Background: TikTok serves as a major source of information. Most content on common skin conditions comes from patients rather than clinicians. Hidradenitis suppurativa disproportionately affects Black women and faces frequent misdiagnosis and delayed care. Understanding content sources and messaging on TikTok remains important.

Objective: This study aimed to describe who produces HS TikTok content featuring Black skin and to quantify the treatments, products, and themes presented.

Methods: TikTok was searched using the phrase "hidradenitis suppurativa in black skin." Fifty videos were reviewed by a single evaluator. Data collected included creator type, board certification status, themes, products mentioned, and commercial involvement such as paid sponsorships or sales commissions.

Results: Among 50 videos, patients produced 24 (48%). Board-certified dermatologists produced 10 (20%) videos, and board-certified plastic surgeons produced seven (14%). Other creators, including nurse practitioners, beauty service providers, and individuals with unclear credentials, accounted for nine videos (18%). Seven videos included products linked to sales commissions, and two involved paid sponsorships. Treatment-related content dominated, appearing in 35 videos (70%). PanOxyl and Hibiclens were the most frequently mentioned products, appearing in five (10%) and six (12%) videos. Fifteen videos (30%) focused on explaining hidradenitis suppurativa, with nine created by healthcare professionals and six by patients. Remaining content emphasized lived experience and dietary approaches.

Conclusions: Patients dominate experiential and lifestyle-focused hidradenitis suppurativa content on TikTok, while physicians primarily provide treatment education. Limited dermatologist representation contributes to gaps between medical guidance and patient-driven narratives. Greater participation by dermatologists on TikTok offers an opportunity to address misinformation, discuss product safety, and provide evidence-based guidance alongside patient experiences.

Clinicaltrial:

背景:TikTok是一个主要的信息来源。大多数关于常见皮肤状况的内容来自患者而不是临床医生。化脓性汗腺炎不成比例地影响黑人妇女,并面临经常误诊和延误护理。了解TikTok的内容来源和消息传递仍然很重要。目的:本研究旨在描述谁生产以黑皮肤为特征的HS TikTok内容,并量化所呈现的治疗、产品和主题。方法:使用“黑色皮肤化脓性汗腺炎”这一短语搜索TikTok。50个视频由一名评价员审查。收集的数据包括创作者类型、董事会认证状态、主题、提到的产品以及商业参与(如付费赞助或销售佣金)。结果:50个视频中,患者制作了24个(48%)。委员会认证的皮肤科医生制作了10个(20%)视频,委员会认证的整形外科医生制作了7个(14%)视频。其他创作者,包括执业护士、美容服务提供商和证书不明确的个人,占9个视频(18%)。7个视频包含与销售佣金相关的产品,2个涉及付费赞助。治疗相关内容占主导地位,出现在35个视频中(70%)。PanOxyl和Hibiclens是最常被提及的产品,分别出现在5个(10%)和6个(12%)视频中。15个视频(30%)专注于解释化脓性汗腺炎,其中9个由医疗保健专业人员制作,6个由患者制作。其余内容强调生活经验和饮食方法。结论:患者主导了TikTok上以体验和生活方式为重点的化脓性汗腺炎内容,而医生主要提供治疗教育。有限的皮肤科医生代表有助于医疗指导和病人驱动的叙述之间的差距。皮肤科医生更多地参与TikTok提供了一个机会,可以解决错误信息,讨论产品安全,并在患者体验的同时提供循证指导。临床试验:
{"title":"The Role of TikTok on the Education of Hidradenitis Suppurativa in Skin of Color: A Cross-Sectional Analysis.","authors":"Arsema K Zadu, Jordan Young, Janyla A Seltzer, Angel S Byrd, Cheri Frey","doi":"10.2196/71566","DOIUrl":"https://doi.org/10.2196/71566","url":null,"abstract":"<p><strong>Background: </strong>TikTok serves as a major source of information. Most content on common skin conditions comes from patients rather than clinicians. Hidradenitis suppurativa disproportionately affects Black women and faces frequent misdiagnosis and delayed care. Understanding content sources and messaging on TikTok remains important.</p><p><strong>Objective: </strong>This study aimed to describe who produces HS TikTok content featuring Black skin and to quantify the treatments, products, and themes presented.</p><p><strong>Methods: </strong>TikTok was searched using the phrase \"hidradenitis suppurativa in black skin.\" Fifty videos were reviewed by a single evaluator. Data collected included creator type, board certification status, themes, products mentioned, and commercial involvement such as paid sponsorships or sales commissions.</p><p><strong>Results: </strong>Among 50 videos, patients produced 24 (48%). Board-certified dermatologists produced 10 (20%) videos, and board-certified plastic surgeons produced seven (14%). Other creators, including nurse practitioners, beauty service providers, and individuals with unclear credentials, accounted for nine videos (18%). Seven videos included products linked to sales commissions, and two involved paid sponsorships. Treatment-related content dominated, appearing in 35 videos (70%). PanOxyl and Hibiclens were the most frequently mentioned products, appearing in five (10%) and six (12%) videos. Fifteen videos (30%) focused on explaining hidradenitis suppurativa, with nine created by healthcare professionals and six by patients. Remaining content emphasized lived experience and dietary approaches.</p><p><strong>Conclusions: </strong>Patients dominate experiential and lifestyle-focused hidradenitis suppurativa content on TikTok, while physicians primarily provide treatment education. Limited dermatologist representation contributes to gaps between medical guidance and patient-driven narratives. Greater participation by dermatologists on TikTok offers an opportunity to address misinformation, discuss product safety, and provide evidence-based guidance alongside patient experiences.</p><p><strong>Clinicaltrial: </strong></p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating Artificial Intelligence Models in Dermatology: Comparative Analysis. 评估皮肤病学中的人工智能模型:比较分析。
Q3 Medicine Pub Date : 2025-12-04 DOI: 10.2196/74040
Aneri Bhargav Patel, William Driscoll, Conan H Lee, Cameron Zachary, Nicole M Golbari, Janellen Smith

Unlabelled: DermGPT demonstrated strong potential for improving answer clarity and conciseness in dermatology-related queries, while ChatGPT provided more robust source citations, enhancing trust in evidence-based responses.

未标记:DermGPT在提高皮肤病学相关查询的答案清晰度和简洁性方面表现出强大的潜力,而ChatGPT提供了更强大的来源引用,增强了对基于证据的回答的信任。
{"title":"Evaluating Artificial Intelligence Models in Dermatology: Comparative Analysis.","authors":"Aneri Bhargav Patel, William Driscoll, Conan H Lee, Cameron Zachary, Nicole M Golbari, Janellen Smith","doi":"10.2196/74040","DOIUrl":"10.2196/74040","url":null,"abstract":"<p><strong>Unlabelled: </strong>DermGPT demonstrated strong potential for improving answer clarity and conciseness in dermatology-related queries, while ChatGPT provided more robust source citations, enhancing trust in evidence-based responses.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e74040"},"PeriodicalIF":0.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12677980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception, Quality, and Accuracy of Sunscreen Content on TikTok: SkinMedia Cross-Sectional Content Analysis. TikTok上防晒霜内容的感知、质量和准确性:SkinMedia横断面内容分析。
Q3 Medicine Pub Date : 2025-12-01 DOI: 10.2196/70010
Jaclyn Roland-McGowan, Kyra Diehl, Tayler Tobey, Autumn Shafer, Paige Clement, Oliver J Wisco, Alex G Ortega-Loayza, Sancy Leachman

Background: TikTok, with more than 2 billion users worldwide, has become an influential venue for health information, including dermatologic advice. However, concerns remain about the accuracy and impact of sunscreen-related content.

Objective: This study aimed to assess the quality, accuracy, and themes of popular TikTok videos about sunscreen; evaluate associations with creator credentials and promotional content; and identify implications for public health.

Methods: We conducted a cross-sectional content analysis of the 100 most-liked English-language TikTok videos generated by the search term "sunscreen." Metadata, creator characteristics, Global Quality Score (GQS), accuracy, attitudes, promotional disclosures, and reference use were extracted using a structured codebook. Thematic and statistical analyses (ie, Pearson correlations, χ2, 2-tailed t tests, and ANOVA) were conducted, with significance defined as P<.05.

Results: Of the top 100 videos, 74 (74%) expressed a positive attitude toward sunscreen, 35 (35%) were accurate, 57 (57%) were opinion based, and 6 (6%) were inaccurate. None of the videos cited references. GQS ratings were low: 40 (40%) videos were rated poor (score=1), 31 (31%) below average (score=2), and only 2 (2%) excellent (score=5). Promotional content appeared in 27 (27%) videos. Accuracy was negatively correlated with likes (r=-0.229; P=.02) and views (r=-0.242; P=.02), while GQS correlated positively with accuracy (r=0.270; P=.007) but not with engagement. Likes and views were strongly correlated (r=0.726; P<.001).

Conclusions: Despite broadly positive sentiment toward sunscreen, misinformation and promotional bias are common in highly engaged TikTok videos, and user engagement is often unrelated to accuracy or educational quality. Dermatologists and public health experts must proactively engage on social platforms to counter misinformation and promote reliable skin health information.

背景:TikTok在全球拥有超过20亿用户,已成为一个有影响力的健康信息平台,包括皮肤病学建议。然而,人们仍然担心防晒霜相关内容的准确性和影响。目的:本研究旨在评估有关防晒霜的热门TikTok视频的质量、准确性和主题;评估与创作者证书和推广内容的关联;并确定对公共卫生的影响。方法:我们对搜索词“防晒霜”生成的100个最受欢迎的英语TikTok视频进行了横断面内容分析。使用结构化代码本提取元数据、创建者特征、全球质量评分(GQS)、准确性、态度、宣传披露和参考使用。进行了主题和统计分析(即Pearson相关性、χ2、双尾t检验和方差分析),显著性定义为结果:在前100个视频中,74个(74%)表达了对防晒霜的积极态度,35个(35%)是准确的,57个(57%)是基于意见的,6个(6%)是不准确的。这些视频都没有引用参考文献。GQS评分较低:40个(40%)视频被评为差(得分=1),31个(31%)视频被评为低于平均水平(得分=2),只有2个(2%)视频被评为优秀(得分=5)。促销内容出现在27个(27%)视频中。准确率与点赞数(r=-0.229; P= 0.02)和浏览量(r=-0.242; P= 0.02)呈负相关,而GQS与准确率(r=0.270; P= 0.07)呈正相关,但与参与度无关。结论:尽管人们对防晒霜普遍持积极态度,但在高参与度的TikTok视频中,错误信息和宣传偏见很常见,用户参与度往往与准确性或教育质量无关。皮肤科医生和公共卫生专家必须积极参与社交平台,以反击错误信息,并推广可靠的皮肤健康信息。
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引用次数: 0
Long-Term Efficacy and Safety of755-nm Alexandrite Laser for Axillary Hair Removal: ِA Comparative Analysis of Single vs. DualFlash lamp Systems. 755 nm紫翠石激光腋毛脱毛的长期疗效和安全性:ِA单闪光灯与双闪光灯系统的比较分析。
Q3 Medicine Pub Date : 2025-11-21 DOI: 10.2196/76523
Kawthar Shurrab, Manal Asad Nassr

Background: Laser hair removal is a noninvasive cosmetic procedure that targets melanin in hair follicles through selective photothermolysis.

Objective: This study aims to evaluate the long-term efficacy and safety of the 755-nm alexandrite laser for axillary hair removal by comparing single- and dual-flash lamp systems.

Methods: In total, 40 women aged 20 to 35 years with Fitzpatrick skin types II and III participated in a study on laser hair removal for their axillae. Participants underwent 3 treatment sessions, each spaced 4 weeks apart, from January to April 2024. They were divided into 2 groups, both receiving treatments with an alexandrite laser (755 nm, 14 mm spot size). The first group was treated with a dose of 8 J/cm² using a single-flash lamp device operating at 5 Hz, with a pulse duration of 10 ms. The second group received doses between 9 and 11 J/cm² from a dual-flash lamp device operating at 2.5 Hz, with pulse durations ranging from 10 to 15 ms. Photographs and hair counts were taken at baseline and 1 month after the final session. A 2-tailed t test was used to assess statistical significance, and regression analysis evaluated treatment effects. Pain scores and side effects were assessed using a visual analog scale in a satisfaction questionnaire.

Results: The dual-flash lamp laser achieved an overall hair reduction of 94%, while the single-flash lamp laser resulted in a 91% reduction in the axilla. The difference was not statistically significant (P=.14). No serious adverse effects were reported with either device, indicating effective safety features.

Conclusions: The outcomes show that both systems provide similar results in terms of efficacy and safety, with no reported side effects, and results were maintained even after 6 and 12 months of follow-up.

背景:激光脱毛是一种非侵入性美容手术,通过选择性光热分解针对毛囊中的黑色素。目的:通过对比单闪光灯和双闪光灯系统,评价755 nm翠绿宝石激光治疗腋毛脱毛的长期疗效和安全性。方法:对40例20 ~ 35岁Fitzpatrick皮肤II型和III型的女性进行腋窝激光脱毛的研究。2024年1月至4月,参与者接受了3次治疗,每次间隔4周。随机分为2组,均采用绿翠石激光(755 nm,光斑尺寸14 mm)处理。第一组使用5 Hz单闪灯装置,脉冲持续时间为10 ms,剂量为8 J/cm²。第二组接受的剂量为9至11 J/cm²,来自2.5 Hz的双闪光灯装置,脉冲持续时间为10至15 ms。在基线和最后一次治疗后1个月拍摄照片和头发计数。采用双尾t检验评价统计学显著性,采用回归分析评价治疗效果。在满意度问卷中使用视觉模拟量表评估疼痛评分和副作用。结果:双闪光灯激光实现了94%的总体毛发减少,而单闪光灯激光导致腋窝减少91%。差异无统计学意义(P= 0.14)。两种设备均未报告严重的不良反应,表明有效的安全特性。结论:结果显示两种系统在疗效和安全性方面提供相似的结果,未报告副作用,并且即使在6个月和12个月的随访后结果仍保持不变。
{"title":"Long-Term Efficacy and Safety of755-nm Alexandrite Laser for Axillary Hair Removal: ِA Comparative Analysis of Single vs. DualFlash lamp Systems.","authors":"Kawthar Shurrab, Manal Asad Nassr","doi":"10.2196/76523","DOIUrl":"10.2196/76523","url":null,"abstract":"<p><strong>Background: </strong>Laser hair removal is a noninvasive cosmetic procedure that targets melanin in hair follicles through selective photothermolysis.</p><p><strong>Objective: </strong>This study aims to evaluate the long-term efficacy and safety of the 755-nm alexandrite laser for axillary hair removal by comparing single- and dual-flash lamp systems.</p><p><strong>Methods: </strong>In total, 40 women aged 20 to 35 years with Fitzpatrick skin types II and III participated in a study on laser hair removal for their axillae. Participants underwent 3 treatment sessions, each spaced 4 weeks apart, from January to April 2024. They were divided into 2 groups, both receiving treatments with an alexandrite laser (755 nm, 14 mm spot size). The first group was treated with a dose of 8 J/cm² using a single-flash lamp device operating at 5 Hz, with a pulse duration of 10 ms. The second group received doses between 9 and 11 J/cm² from a dual-flash lamp device operating at 2.5 Hz, with pulse durations ranging from 10 to 15 ms. Photographs and hair counts were taken at baseline and 1 month after the final session. A 2-tailed t test was used to assess statistical significance, and regression analysis evaluated treatment effects. Pain scores and side effects were assessed using a visual analog scale in a satisfaction questionnaire.</p><p><strong>Results: </strong>The dual-flash lamp laser achieved an overall hair reduction of 94%, while the single-flash lamp laser resulted in a 91% reduction in the axilla. The difference was not statistically significant (P=.14). No serious adverse effects were reported with either device, indicating effective safety features.</p><p><strong>Conclusions: </strong>The outcomes show that both systems provide similar results in terms of efficacy and safety, with no reported side effects, and results were maintained even after 6 and 12 months of follow-up.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e76523"},"PeriodicalIF":0.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12638035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145574995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichoscopic Differentiation in Alopecia: Retrospective Case Series Comparing Lichen Planopilaris, Discoid Lupus Erythematosus, and Alopecia Areata. 斑秃的毛镜鉴别:比较扁平苔藓、盘状红斑狼疮和斑秃的回顾性病例系列。
Q3 Medicine Pub Date : 2025-11-20 DOI: 10.2196/83463
Gökhan Kaya

Unlabelled: This single-center retrospective case series included 28 patients with alopecia (7 with lichen planopilaris, 7 with discoid lupus erythematosus, and 14 with alopecia areata). Trichoscopic markers were systematically compared across groups. Exclamation-mark hairs and yellow dots were characteristic of alopecia areata, whereas follicular ostia loss and white scarring were confined to lichen planopilaris/discoid lupus erythematosus, providing a simple and practical distinction between nonscarring and scarring alopecias in routine practice.

未标记:该单中心回顾性病例系列包括28例脱发患者(7例为扁平秃苔,7例为盘状红斑狼疮,14例为斑秃)。系统比较各组间的毛镜标记物。斑秃是斑秃的特征,而毛囊开口缺失和白色瘢痕仅限于扁平苔藓/盘状红斑狼疮,这在常规实践中为非瘢痕性脱发和瘢痕性脱发提供了简单而实用的区分。
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引用次数: 0
Teledermatology to Support Self-Care in Chronic Spontaneous Urticaria. 远程皮肤科支持慢性自发性荨麻疹患者的自我护理。
Q3 Medicine Pub Date : 2025-11-13 DOI: 10.2196/81830
Laura Schuehlein, Martin Peters, Graham Jones

Unlabelled: Chronic spontaneous urticaria (CSU) is an autoimmune prompted skin disorder, whose hallmarks include the unpredictable onset of hives and itch. Symptom duration typically exceed 6 weeks, and flares can occur for up to 5 years or longer if untreated, impacting potentially any area of the body. The absence of obvious triggers and the variation in onset frequency often delays formal diagnosis which on average is approximately 2 years from first presentation. Initial standard of care is the use of low through to higher strength antihistamines in the first instance, with eventual escalation to prescription anti-inflammatory agents and potentially biologics once patients are under managed care. The societal impacts of delays in diagnosis are marked, with data suggesting CSU impacts up to 1% of the population, primarily of working age and with twice the prevalence in women. Herein, we advocate for the deployment of smartphone imaging and generative artificial intelligence technology to improve detection and early management of CSU through integrated self-care approaches. Such approaches embodying the tenets of P4 personalized medicine could have sustained impact on the disease through awareness campaigns, reducing the burden on the dermatology community and facilitating earlier access to curative therapeutic interventions.

未标记:慢性自发性荨麻疹(CSU)是一种自身免疫性皮肤病,其特征包括不可预测的荨麻疹和瘙痒。症状持续时间通常超过6周,如果不治疗,发作可长达5年或更长时间,可能影响身体的任何部位。缺乏明显的诱因和发病频率的变化往往延迟正式诊断,从首次出现平均约2年。最初的治疗标准是首先使用从低到高强度的抗组胺药,一旦患者接受管理治疗,最终升级为处方抗炎药和潜在的生物制剂。诊断延误的社会影响是明显的,数据表明,CSU影响人口的1%,主要是工作年龄,妇女患病率是其两倍。在此,我们提倡部署智能手机成像和生成人工智能技术,通过综合自我护理方法改善CSU的检测和早期管理。这种体现P4个性化医疗原则的方法可以通过提高认识运动、减轻皮肤病界的负担和促进尽早获得治愈性治疗干预措施,对该疾病产生持续影响。
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JMIR dermatology
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