Journal of advanced periodontology & implant dentistry最新文献

Background: Inferior alveolar nerve damage can lead to mild to severe paresthesia and even facial pain. One of the treatments considered today for the reconstruction and treatment of damaged peripheral nerves is the use of vitamin supplements. This study aimed to evaluate the effect of vitamin B complex supplementation on pain and sensory problems following mandibular implant placement surgery.

Methods: In this single-blind clinical trial, 46 patients applying for implant placement, who were eligible for the study, were evaluated. All the patients were examined for sensory facial injury and inferior alveolar nerve injury within 24 hours after implant placement. The nerve damage was recorded by AI (asymmetry index) in the initial examination. Patients who reported clinical and radiographic signs of nerve damage due to implant or drill impingement of the nerve canal were excluded from the study and promptly treated with anti-inflammatory protocols. Then the patients were randomly divided into control (n=23) and intervention (n=23) groups. Patients in the control group received routine treatment after implantation, and patients in the intervention group received vitamin B complex pills in addition to routine treatment. A placebo was used to eliminate the inductive effect of the drug in the control group. Follow-up of patients was performed at intervals of 14 days and 1, 2, and 3 months after treatment. Data analysis was performed using SPSS 24 and Kruskal-Wallis, Wilcoxon, and chi-squared tests.

Results: In both groups, a decreasing trend in pain intensity was observed for up to three months. There were no significant differences between the mean pain intensity in the intervention and control groups at all the follow-up intervals. In both groups, a decrease in the rate of paresthesia was observed during the 3-month follow-up. The mean of paresthesia in the two groups was not significantly different at any follow-up interval.

Conclusion: Vitamin B complex might not affect pain intensity and paresthesia after implant surgery.

Chloroform is used widely in endodontic treatments for solving gutta-percha points, but it can have destructive effects if it comes in to contact with oral mucosa. This article presents a case of necrotic ulcer of palatal and buccal mucosa due to injudicious use of chloroform in endodontic treatment, which has caused severe destruction in maxilla. A conservative treatment method of repeated curettage and irrigation was used and although the lesion healed completely, it had major effects on the patient's quality of life including loss of two teeth. It is important that dentist be aware of the devastating effects of imprudent application of various chemicals used in dentistry. The conservative treatment used for this case can be helpful option for similar cases.

Background: This clinical trial evaluated the effect of coenzyme Q10 supplementation along with scaling and root planing (SRP) on periodontal and gingival indices in controlled diabetic patients.

Methods: Forty-two diabetic patients (controlled type), referred to the Department of Periodontics with chronic periodontitis and eligible for the study, were included in the study. Patients suffering from chronic periodontitis with a probing pocket depth of ≥5 mm in different quadrants of the oral cavity with radiographic evidence of bone loss were included in the present randomized, double-masked, placebo-controlled clinical trial. The subjects were instructed to take one capsule of coenzyme Q10 or a placebo every day for 30 days following SRP. Clinical parameters, i.e., plaque index (PI), gingival index (GI), bleeding on probing (BOP), clinical attachment level (CAL), and probing pocket depth (PPD), were recorded at baseline and four weeks after treatment by two masked and calibrated examiners. The study results were reported as (mean ± standard deviations) and frequencies (percentages).

Results: One month after the intervention, PPD, CAL, BOP, and PI indices in the intervention group were significantly lower than those in the control group. One month after the intervention, the GI was similar in both groups. A significant decrease was observed in the GI in both groups after the intervention.

Conclusion: The results of the present study showed that Q10 orally with scaling and root planing in patients with controlled diabetes with chronic periodontitis might accelerate the treatment process and significantly reduce the pocket depth.

Periodontitis can lead to the loss of hard and soft tissues of the oral cavity. Dental implants have become a reliable treatment modality in recent times, especially with the evolution of digital technology such as CBCT, implant planning software, computer-assisted manufacturing, and guided implant surgery. Documentation of such advancements and their clinical implications would add to the existing knowledge on implant dentistry, encouraging dentists to approach complex implant surgeries confidently. This paper discusses the rehabilitation of missing teeth by applying computer-assisted guided implant placement in two cases with deficient bone volume anteriorly and posteriorly in the maxilla, respectively. Digital planning and careful execution have resulted in precise implant placement and complete osseointegration. In these cases, we could devise treatment plans with both anatomical and prosthetic considerations while being minimally invasive and more predictable, with shorter treatment time and greater patient comfort.

Background: The current study tested netrin-1 as a reliable inflammatory marker of periodontal disease.

Methods: Gingival crevicular fluid (GCF) samples were taken at baseline from 30 systemically healthy individuals. Fifteen subjects had stage II grade A or B periodontitis, and 15 were periodontally and clinically healthy. Whole-mouth periodontal parameters [probing depth (PD), clinical attachment loss (CAL), plaque index (PI), and gingival index (GI)] were recorded. The GCF samples were re-collected, and clinical parameters were re-recorded after six weeks following full-mouth scaling and root planing (SRP) in the periodontitis group.

Results: Netrin-1 GCF levels were significantly lower in periodontitis patients than periodontally healthy individuals at baseline with a significant increase in netrin-1 GCF levels after SRP (P<0.05).

Conclusion: Netrin-1 may have a significant role in the inflammatory process of chronic periodontitis; thus, it could be a promising anti-inflammatory marker in periodontal disease.

Background. A decrease in the width and height of the alveolar ridge is inevitable following tooth extraction. This study aimed to histologically evaluate the amount of newly formed bone after using a freeze-dried bone allograft (FDBA) at two different intervals in the tooth socket grafting. Methods. Forty patients were selected, who required a single-rooted tooth extraction and were candidates for implant placement, with no indication for an immediate implant. Extraction sockets were preserved using a cortical FDBA allograft in two regeneration interval groups: 3 months (group A) and 4 months (group B). At the time of implant placement, a bone sample was collected from each grafted socket. Histomorphometric analyses were performed to determine the percentage of newly formed bone and the residual graft material. Changes in histological indices, i.e., inflammation rate, percentage of ossification, and the amount of remaining biomaterial, were evaluated. Results. There were no significant differences in the amount of newly formed bone and residual graft material between the two groups. In general, the average of new bone formation and remaining graft particles in groups A and B was: %33.89 and %12.59 vs. %39.83 and %14.07, respectively. Conclusion. Bone parameters in group A were better compared to group B. However, due to the lack of significant differences in the results, it is suggested that implant placement in grafted sockets with mineralized allografts be expedited.

Background. The aim of this study was the clinical and laboratory evaluation of using polycaprolactone (PCL) nanofibers loaded with oxytetracycline hydrochloride (OTC) and zinc oxide (ZnO) as an adjunct to mechanical therapy in managing stage II grade A periodontitis patients concerning GCF lipocalin2- levels. Methods. Fifty stage II grade A periodontitis patients (27 women and 23 men, with an age range of 30‒60) were enrolled in the study. The patients were randomly assigned to five equal groups and treated with scaling and root planing (SRP), followed by local application of PCL nanofibers: group I: SRP + PCL loaded with OTC and ZnO, group II: SRP + PCL loaded with OTC, group III: SRP + PCL loaded with ZnO, group IV: SRP + unloaded PCL, and group V: SRP alone. Additionally, 10 healthy subjects with healthy periodontium (group VI) (age- and gender-matched) served as the negative control. Nanofibers were applied in the selected pockets of periodontitis patients in groups I to IV once weekly for two months. All the participants were examined clinically by assessing periodontal indices (gingival index, plaque index, pocket depth, and clinical attachment level), and biochemically by assessing GCF lipocalin-2 levels. Results. Compared to controls, periodontitis groups (I, II, III, IV, and V) showed significant elevation of both clinical parameters and GCF lipocalin2- levels at baseline. In addition, these parameters improved significantly after treatment, which was more pronounced in groups I, II-, and III) compared to groups IV and V. However, it did not reach normal values. Conclusion. In association with SRP, PCL nanofibers loaded with OTC and ZnO had beneficial therapeutic effects at both clinical and laboratory levels.

Background. Limited evidence is available on the effect of milk as a mouthwash on treating dentin hypersensitivity. The present study aimed to compare the effect of milk as a mouthwash with one anti-hypersensitivity mouthwash in decreasing dentin hypersensitivity after non-surgical periodontal treatment. Methods. Patients with generalized moderate-to-severe chronic periodontitis were selected randomly in the present study and underwent scaling and root planing (SRP). Seventy patients with severe dentin hypersensitivity after two days were assigned to two groups. In group A, the patients were asked to use milk as a mouthwash, and in group B, the patients were asked to use anti-hypersensitiv-ity Misswake mouthwash. The patients' hypersensitivity was measured during follow-up visits. The independent t-test was used to compare denim hypersensitivity between the two groups. Statistical significance was set at P<0.05. Results. The results showed a significant decrease in dentin hypersensitivity in both groups on days 15 and 30. In the milk group, 11 and 29 patients fully recovered from dentin hypersensitivity on days 15 and 30, respectively. However, in the anti-hypersensitivity mouthwash group, 8 and 27 patients fully recovered from dentin hypersensitivity on days 15 and 30, respectively. Therefore, more patients benefited from the anti-hypersensitivity effects of milk as a mouthwash. However, the differences were not significant during the whole treatment sessions. Conclusion. Using milk as an inexpensive and available mouthwash can decrease dentin hypersensi-tivity after SRP.

Microsurgery has evolved, permitting faster vascularization and healing than macro-interventions, reducing tissue trauma and obtaining precise wound closure. Therefore, this study aimed to detail the initial healing steps after the periodontal microsurgical procedure. A -26 year-old female had a localized recession (anterior lower tooth, recession type1-), with the absence of local keratinized tissue width (KTW) and adjacent gingival thickness (GT)<1 mm. After oral prophylaxis and occlusal adjustments, the pink esthetic score was performed (5 points), followed by the microsurgery procedure. Prior to inserting the subepithelial connective tissue graft (SCTG), the epithelial layer was removed, and the root surface was biomodified. Two days postoperatively, it was possible to observe a white layer from the SCTG in the gingival margin, decreasing after 4 days. In 6 days, the sutures were removed; no graft and volume loss was observed. For 9 days, the volume was the maintenance. Nevertheless, there was a reduction in tissue volume in the facial zone. After 11 and 13 days, an improved healing process was found, whereas, after 16 days, it was possible to report stable tissues, which was confirmed after 31 days, with a significant GR reduction and an increase in KTW and GT. Moreover, the final pink esthetic score (PES) was 9. Microsurgery had a faster healing and predictable outcome, suggesting reduced trauma, which may allow a quicker suture removal without jeopardizing the outcomes.