首页 > 最新文献

Journal of psychopathology and clinical science最新文献

英文 中文
Prospective examination of mechanisms linking minority stress and anxious/depressed affect at the event level: The roles of emotion regulation strategies and proximal minority stressors. 在事件层面对少数群体压力与焦虑/抑郁情绪之间的联系机制进行前瞻性研究:情绪调节策略和近端少数群体压力源的作用。
Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000882
Christina Dyar

Background: While studies have linked sexual minority stress with anxious/depressed affect, few studies have prospectively examined how mechanistic processes linking minority stress and anxious/depressed affect unfold in near-real time. Furthermore, studies of mechanisms have focused exclusively on rumination and proximal minority stressors (e.g., internalized stigma). This limits our understanding of other potential mechanisms, such as decreases in the use of reappraisal and reflection, strategies associated with reducing anxious/depressed affect.

Method: We used data from a 30-day ecological momentary assessment study with 429 sexual minority women and gender diverse sexual minorities assigned female at birth to determine whether concurrent and prospective event-level associations between minority stress and anxious/depressed affect were mediated by changes in six emotion regulation strategies, perceived coping efficacy, and proximal stressors.

Results: In partially lagged analyses, when individuals experienced enacted or internalized stigma, they reported increased rumination and expressive suppression on the same day, which predicted increases in anxious/depressed affect into the next day. Decreases in reappraisal also mediated partially lagged associations between internalized stigma and anxious/depressed affect. Fully lagged mediation was only demonstrated for rumination as a mechanism linking internalized stigma with anxious/depressed affect. We found concurrent evidence for other mechanisms (i.e., perceived coping efficacy, reflection, internalized stigma, and rejection sensitivity).

Conclusions: Results provided support for the roles of rumination and expressive suppression as mechanisms of linking minority stress and anxious/depressed affect. The concurrent evidence for other mechanisms suggests that future research with more temporal resolution is necessary to determine the temporality and directionality of these associations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

背景:虽然已有研究将性少数群体的压力与焦虑/抑郁情绪联系起来,但很少有研究对少数群体压力与焦虑/抑郁情绪之间的机理过程是如何在近乎真实的时间内展开的进行了前瞻性研究。此外,对机制的研究只关注反刍和少数群体的近端压力源(如内化的污名化)。这就限制了我们对其他潜在机制的了解,如减少使用重新评估和反思等与减轻焦虑/抑郁情绪相关的策略:我们利用对 429 名性少数群体女性和出生时被分配为女性的不同性别的性少数群体进行的一项为期 30 天的生态瞬间评估研究的数据,来确定少数群体压力与焦虑/抑郁情绪之间的并发和前瞻性事件水平关联是否受六种情绪调节策略、感知应对效能和近端压力源变化的影响:结果发现:在部分滞后分析中,当个体经历了成见或内化成见时,他们会在同一天报告反刍和表达性抑制的增加,这预示着焦虑/抑郁情绪会在第二天增加。重新评价的减少也对内化成见与焦虑/抑郁情绪之间的部分滞后关联起到了中介作用。只有反刍作为内化成见与焦虑/抑郁情绪之间的联系机制,证明了完全滞后的中介作用。我们同时发现了其他机制(即感知到的应对效能、反思、内在化成见和拒绝敏感性)的证据:结论:研究结果支持反刍和表达性抑制是少数群体压力与焦虑/抑郁情绪的关联机制。研究结果支持反刍和表达性抑制是少数群体压力和焦虑/抑郁情绪之间的关联机制,同时也证明了其他机制的存在,这表明今后有必要开展时间分辨率更高的研究,以确定这些关联的时间性和方向性。(PsycInfo Database Record (c) 2023 APA, 版权所有)。
{"title":"Prospective examination of mechanisms linking minority stress and anxious/depressed affect at the event level: The roles of emotion regulation strategies and proximal minority stressors.","authors":"Christina Dyar","doi":"10.1037/abn0000882","DOIUrl":"10.1037/abn0000882","url":null,"abstract":"<p><strong>Background: </strong>While studies have linked sexual minority stress with anxious/depressed affect, few studies have prospectively examined how mechanistic processes linking minority stress and anxious/depressed affect unfold in near-real time. Furthermore, studies of mechanisms have focused exclusively on rumination and proximal minority stressors (e.g., internalized stigma). This limits our understanding of other potential mechanisms, such as decreases in the use of reappraisal and reflection, strategies associated with reducing anxious/depressed affect.</p><p><strong>Method: </strong>We used data from a 30-day ecological momentary assessment study with 429 sexual minority women and gender diverse sexual minorities assigned female at birth to determine whether concurrent and prospective event-level associations between minority stress and anxious/depressed affect were mediated by changes in six emotion regulation strategies, perceived coping efficacy, and proximal stressors.</p><p><strong>Results: </strong>In partially lagged analyses, when individuals experienced enacted or internalized stigma, they reported increased rumination and expressive suppression on the same day, which predicted increases in anxious/depressed affect into the next day. Decreases in reappraisal also mediated partially lagged associations between internalized stigma and anxious/depressed affect. Fully lagged mediation was only demonstrated for rumination as a mechanism linking internalized stigma with anxious/depressed affect. We found concurrent evidence for other mechanisms (i.e., perceived coping efficacy, reflection, internalized stigma, and rejection sensitivity).</p><p><strong>Conclusions: </strong>Results provided support for the roles of rumination and expressive suppression as mechanisms of linking minority stress and anxious/depressed affect. The concurrent evidence for other mechanisms suggests that future research with more temporal resolution is necessary to determine the temporality and directionality of these associations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10842229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The affective benefits of real-world exploration during the COVID-19 pandemic. 在 COVID-19 大流行期间,真实世界探索带来的情感益处。
Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000888
T Rick Reneau, William J Villano, Brittany A Jaso, Aaron S Heller

Increasing daily exploration is linked to improvements in affective well-being. However, COVID-19 elevated uncertainty when leaving the home, altering the risk-reward of balance of geospatial novelty. To this end, we simultaneously collected real-world geospatial tracking and experience sampling of emotion, prior to and during the first year of the pandemic in 630 individuals. COVID-19 reduced exploration and subjective well-being. Yet, despite the health risks of exploring during the pandemic, the days of highest affective well-being were those when individuals explored the most. However, this was not true for everyone: during the first months of the pandemic, at the height of the uncertainty surrounding the transmissibility and prognosis of a COVID-19 infection, more anxious individuals experienced no affective benefit to leaving home. Taken together, real-world exploration improved well-being regardless of the presence of real-world threat, but anxiety mitigated these benefits. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

日常探索的增加与情感幸福感的改善有关。然而,COVID-19 增加了离家时的不确定性,改变了地理空间新奇性平衡的风险回报。为此,我们在大流行之前和第一年期间同时收集了 630 人的真实世界地理空间跟踪和情感体验取样。COVID-19 减少了探索和主观幸福感。然而,尽管在大流行期间进行探索会带来健康风险,但在个人探索最多的日子里,他们的情感幸福感也最高。然而,并非每个人都是如此:在大流行的头几个月,在围绕 COVID-19 感染的传播性和预后的不确定性最高的时候,更焦虑的人离家出走并没有带来任何情感上的益处。综上所述,无论现实世界是否存在威胁,对现实世界的探索都会提高人们的幸福感,但焦虑会减轻这些益处。(PsycInfo Database Record (c) 2023 APA, 版权所有)。
{"title":"The affective benefits of real-world exploration during the COVID-19 pandemic.","authors":"T Rick Reneau, William J Villano, Brittany A Jaso, Aaron S Heller","doi":"10.1037/abn0000888","DOIUrl":"10.1037/abn0000888","url":null,"abstract":"<p><p>Increasing daily exploration is linked to improvements in affective well-being. However, COVID-19 elevated uncertainty when leaving the home, altering the risk-reward of balance of geospatial novelty. To this end, we simultaneously collected real-world geospatial tracking and experience sampling of emotion, prior to and during the first year of the pandemic in 630 individuals. COVID-19 reduced exploration and subjective well-being. Yet, despite the health risks of exploring during the pandemic, the days of highest affective well-being were those when individuals explored the most. However, this was not true for everyone: during the first months of the pandemic, at the height of the uncertainty surrounding the transmissibility and prognosis of a COVID-19 infection, more anxious individuals experienced no affective benefit to leaving home. Taken together, real-world exploration improved well-being regardless of the presence of real-world threat, but anxiety mitigated these benefits. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posttraumatic symptoms and poor sleep are independent pathways to agency disruptions and dissociation: A longitudinal study with objective sleep assessment. 创伤后症状和睡眠不佳是导致机构混乱和分离的独立途径:通过客观睡眠评估进行的纵向研究。
Pub Date : 2024-02-01 Epub Date: 2023-12-18 DOI: 10.1037/abn0000885
Noa Bregman-Hai, Nirit Soffer-Dudek

Dissociation and diminished sense of agency are experiential distortions of disintegration in the perception of self and action. Although one is often implied in the other, they are seldom studied together. Assessing their relationship and shared influences may allow for a more comprehensive and nuanced understanding of dissociative experiences. We aimed to examine their temporal (concurrent or directional) co-occurrence, and to elucidate their etiology, focusing on posttraumatic symptoms (PTS), poor sleep, and their hypothesized joint effect. N = 113 adults oversampled for the existence of trauma exposure history reported PTS and then, for a week, wore an actigraphic sleep monitor, reported subjective sleep quality each morning, and reported state dissociation (depersonalization, derealization, and absorption) and sense of agency four times each day. Data were analyzed using multilevel linear modeling. Higher state dissociation correlated with diminished state sense of agency, but only contemporaneously, not directionally. Both hypothesized etiological factors, namely, PTS (especially complex) and poor sleep (objective and subjective) predicted state dissociation and diminished state sense of agency, but psychological distress seemed to overshadow these main effects. However, robust interactive effects suggested that poor sleep predicted dissociation and disruptions in the sense of agency only among individuals with low PTS. These findings suggest that PTS and poor sleep quality are separate paths to dissociation and impaired sense of agency. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

解离和代理感减弱是自我感知和行动解体的经验扭曲。虽然其中一个往往暗示着另一个,但很少将它们放在一起研究。对它们之间的关系和共同影响进行评估,可以更全面、更细致地了解解离体验。我们的目的是研究它们在时间上(同时或定向)的共存性,并阐明它们的病因,重点是创伤后症状(PTS)、睡眠不佳以及它们假设的共同影响。对 113 名成年人进行了超量抽样调查,以确定他们是否存在创伤暴露史,并报告了创伤后应激障碍,然后在一周内佩戴睡眠监测仪,每天早上报告主观睡眠质量,每天四次报告状态解离(人格解体、去人格化和吸收)和代入感。数据采用多层次线性模型进行分析。较高的状态分离度与较低的状态代入感相关,但只是同时存在,而非定向相关。两个假设的病因因素,即创伤后应激障碍(尤其是复杂的)和睡眠不佳(客观和主观),都能预测状态解离和状态代入感的减弱,但心理困扰似乎掩盖了这些主要效应。然而,强大的交互效应表明,只有在 PTS 较低的个体中,睡眠不佳才会预测解离和代理感的中断。这些研究结果表明,创伤后应激障碍和睡眠质量差是导致解离和代理感受损的不同途径。(PsycInfo Database Record (c) 2023 APA, 版权所有)。
{"title":"Posttraumatic symptoms and poor sleep are independent pathways to agency disruptions and dissociation: A longitudinal study with objective sleep assessment.","authors":"Noa Bregman-Hai, Nirit Soffer-Dudek","doi":"10.1037/abn0000885","DOIUrl":"10.1037/abn0000885","url":null,"abstract":"<p><p>Dissociation and diminished sense of agency are experiential distortions of disintegration in the perception of self and action. Although one is often implied in the other, they are seldom studied together. Assessing their relationship and shared influences may allow for a more comprehensive and nuanced understanding of dissociative experiences. We aimed to examine their temporal (concurrent or directional) co-occurrence, and to elucidate their etiology, focusing on posttraumatic symptoms (PTS), poor sleep, and their hypothesized joint effect. N = 113 adults oversampled for the existence of trauma exposure history reported PTS and then, for a week, wore an actigraphic sleep monitor, reported subjective sleep quality each morning, and reported state dissociation (depersonalization, derealization, and absorption) and sense of agency four times each day. Data were analyzed using multilevel linear modeling. Higher state dissociation correlated with diminished state sense of agency, but only contemporaneously, not directionally. Both hypothesized etiological factors, namely, PTS (especially complex) and poor sleep (objective and subjective) predicted state dissociation and diminished state sense of agency, but psychological distress seemed to overshadow these main effects. However, robust interactive effects suggested that poor sleep predicted dissociation and disruptions in the sense of agency only among individuals with low PTS. These findings suggest that PTS and poor sleep quality are separate paths to dissociation and impaired sense of agency. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily prediction of inpatient suicide attempts using routinely collected theory-driven data. 利用日常收集的理论数据,对住院病人企图自杀的情况进行日常预测。
Pub Date : 2024-02-01 Epub Date: 2023-12-14 DOI: 10.1037/abn0000880
Michael J Kyron, Geoff R Hooke, Craig J Bryan, Glenn Kiekens, Wai Chen, Nikhila Udupa, Thomas Joiner, Andrew C Page

We lack knowledge about the short-term predictors of suicide attempts (SAs) among treatment-seeking individuals. The current study evaluated whether (a) interpersonal difficulties, hopelessness, and affective states are associated with an increased risk of SAs on the same and the next day; (b) these daily states are interconnected differently over time among inpatients who attempt suicide compared to those who do not. In total, 110 psychiatric inpatients who attempted suicide during their stay at a psychiatric hospital self-reported their suicidal ideation, negative affect, positive affect, wish to live, interpersonal needs, and hopelessness each day (3,018 daily reports). Multilevel structural equation modeling was used to examine same-day and next-day predictors of SAs. Multilevel temporal network models assessed interconnectedness between daily predictors and were compared to network models from a matched sample of 110 psychiatric inpatients who did not attempt suicide. In multivariate models, increases in perceived burdensomeness were significantly associated with same-day SAs, whereas increased hopelessness was associated with next-day SAs. Network models for patients who attempted suicide indicated that hopelessness and suicidal ideation were central to change, leading to next-day deteriorations in mental health. In subsequent models, feeling calm and relaxed, and feeling fresh and rested were centrally connected to other variables. The centrality of these metrics tended to be higher than in the network models for patients who did not attempt suicide, suggesting differences in the interplay between risk and protective factors. This study suggests routinely monitoring interpersonal factors and hopelessness may help identify increased short-term risk of SAs among psychiatric inpatients. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

我们对寻求治疗者自杀未遂(SAs)的短期预测因素缺乏了解。本研究评估了:(a) 人际交往困难、绝望和情感状态是否与当日和次日自杀未遂风险的增加有关;(b) 在企图自杀的住院患者中,这些日常状态随着时间的推移与未自杀者相比是否有不同的关联。共有 110 名在精神病院住院期间试图自杀的精神病住院患者自我报告了他们每天的自杀意念、消极情绪、积极情绪、求生愿望、人际需求和绝望感(3018 份每日报告)。多层次结构方程模型用于研究当日和次日自杀行为的预测因素。多层次时间网络模型评估了每日预测因素之间的相互关联性,并与 110 名未试图自杀的精神病住院患者的匹配样本网络模型进行了比较。在多变量模型中,感知到的负担感的增加与当天的自杀行为显著相关,而绝望感的增加与次日的自杀行为相关。针对自杀未遂患者的网络模型表明,绝望和自杀意念是导致第二天心理健康状况恶化的主要原因。在随后的模型中,平静和放松的感觉以及清爽和休息的感觉是与其他变量相关的核心因素。这些指标的中心性往往高于未试图自杀的患者的网络模型,这表明风险因素和保护因素之间的相互作用存在差异。这项研究表明,对人际关系因素和绝望情绪进行常规监测有助于识别精神病住院患者短期内增加的自杀风险。(PsycInfo Database Record (c) 2023 APA,保留所有权利)。
{"title":"Daily prediction of inpatient suicide attempts using routinely collected theory-driven data.","authors":"Michael J Kyron, Geoff R Hooke, Craig J Bryan, Glenn Kiekens, Wai Chen, Nikhila Udupa, Thomas Joiner, Andrew C Page","doi":"10.1037/abn0000880","DOIUrl":"10.1037/abn0000880","url":null,"abstract":"<p><p>We lack knowledge about the short-term predictors of suicide attempts (SAs) among treatment-seeking individuals. The current study evaluated whether (a) interpersonal difficulties, hopelessness, and affective states are associated with an increased risk of SAs on the same and the next day; (b) these daily states are interconnected differently over time among inpatients who attempt suicide compared to those who do not. In total, 110 psychiatric inpatients who attempted suicide during their stay at a psychiatric hospital self-reported their suicidal ideation, negative affect, positive affect, wish to live, interpersonal needs, and hopelessness each day (3,018 daily reports). Multilevel structural equation modeling was used to examine same-day and next-day predictors of SAs. Multilevel temporal network models assessed interconnectedness between daily predictors and were compared to network models from a matched sample of 110 psychiatric inpatients who did not attempt suicide. In multivariate models, increases in perceived burdensomeness were significantly associated with same-day SAs, whereas increased hopelessness was associated with next-day SAs. Network models for patients who attempted suicide indicated that hopelessness and suicidal ideation were central to change, leading to next-day deteriorations in mental health. In subsequent models, feeling calm and relaxed, and feeling fresh and rested were centrally connected to other variables. The centrality of these metrics tended to be higher than in the network models for patients who did not attempt suicide, suggesting differences in the interplay between risk and protective factors. This study suggests routinely monitoring interpersonal factors and hopelessness may help identify increased short-term risk of SAs among psychiatric inpatients. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal dynamics between anxiety and depression in bipolar spectrum disorders. 双相情感障碍中焦虑与抑郁之间的纵向动态关系。
Pub Date : 2024-02-01 Epub Date: 2024-01-08 DOI: 10.1037/abn0000890
Hanjoo Kim, Melvin G McInnis, Sarah H Sperry

Anxiety and depression are common among individuals with bipolar spectrum disorders (BSDs), with anxiety being a risk factor for depression and vice versa. While the harmful effects of these symptoms are well recognized, their temporal dynamics have not been fully tested. To address this gap, our study investigated bidirectional relationships between anxiety and depression in individuals with BSDs using data from the Prechter Longitudinal Study of Bipolar Disorder, collected over an average of 11 years. We included 651 participants with various BSD subtypes (BD I, BD II, BD not otherwise specified, and schizoaffective bipolar type), with at least 5 years' data for adequate statistical power in detecting temporal dynamics. Bimonthly measurements of anxiety and depression were analyzed using dynamic structural equation modeling. Beyond assessing autoregressive and cross-lagged effects, this study also investigated whether temporal dynamics differed based on demographic characteristics and the use of psychiatric medication. Our findings revealed that individuals with BSDs experienced significant fluctuations in anxiety and depression over time. In addition, we found significant autoregressive and cross-lagged effects of anxiety and depression. Comparison of the cross-lagged effects demonstrated that anxiety had a greater effect on subsequent depression than vice versa. Age and marital status impacted cross-lagged and autoregressive effects. Specifically, older participants had stronger temporal associations between depression and subsequent anxiety, while widowed participants exhibited a heightened impact of depression on subsequent depression. These results underscore the importance of early identification and integrative interventions aimed at addressing both anxiety and depression to mitigate subsequent symptoms in BSDs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

焦虑和抑郁在双相情感障碍(BSD)患者中很常见,焦虑是抑郁的风险因素,反之亦然。虽然这些症状的有害影响已得到广泛认可,但它们的时间动态尚未得到充分检验。为了填补这一空白,我们的研究利用普雷希特双相情感障碍纵向研究(Prechter Longitudinal Study of Bipolar Disorder)平均 11 年的数据,调查了双相情感障碍患者焦虑和抑郁之间的双向关系。我们纳入了 651 名患有不同 BSD 亚型(BD I、BD II、未另作规定的 BD 和分裂情感双相情感障碍类型)的参与者,这些参与者至少有 5 年的数据,因此在检测时间动态方面具有足够的统计能力。采用动态结构方程模型对焦虑和抑郁的双月测量结果进行分析。除了评估自回归和交叉滞后效应外,本研究还调查了时间动态是否因人口统计学特征和精神科药物的使用而有所不同。我们的研究结果表明,BSD 患者的焦虑和抑郁情绪会随着时间的推移而发生显著波动。此外,我们还发现焦虑和抑郁具有明显的自回归和交叉滞后效应。交叉滞后效应的比较表明,焦虑对后续抑郁的影响比反之更大。年龄和婚姻状况影响了交叉滞后效应和自回归效应。具体来说,年龄较大的参与者在抑郁和后续焦虑之间具有更强的时间关联,而丧偶的参与者则表现出抑郁对后续抑郁的影响更大。这些结果强调了早期识别和综合干预的重要性,旨在同时解决焦虑和抑郁问题,以减轻 BSD 的后续症状。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
{"title":"Longitudinal dynamics between anxiety and depression in bipolar spectrum disorders.","authors":"Hanjoo Kim, Melvin G McInnis, Sarah H Sperry","doi":"10.1037/abn0000890","DOIUrl":"10.1037/abn0000890","url":null,"abstract":"<p><p>Anxiety and depression are common among individuals with bipolar spectrum disorders (BSDs), with anxiety being a risk factor for depression and vice versa. While the harmful effects of these symptoms are well recognized, their temporal dynamics have not been fully tested. To address this gap, our study investigated bidirectional relationships between anxiety and depression in individuals with BSDs using data from the Prechter Longitudinal Study of Bipolar Disorder, collected over an average of 11 years. We included 651 participants with various BSD subtypes (BD I, BD II, BD not otherwise specified, and schizoaffective bipolar type), with at least 5 years' data for adequate statistical power in detecting temporal dynamics. Bimonthly measurements of anxiety and depression were analyzed using dynamic structural equation modeling. Beyond assessing autoregressive and cross-lagged effects, this study also investigated whether temporal dynamics differed based on demographic characteristics and the use of psychiatric medication. Our findings revealed that individuals with BSDs experienced significant fluctuations in anxiety and depression over time. In addition, we found significant autoregressive and cross-lagged effects of anxiety and depression. Comparison of the cross-lagged effects demonstrated that anxiety had a greater effect on subsequent depression than vice versa. Age and marital status impacted cross-lagged and autoregressive effects. Specifically, older participants had stronger temporal associations between depression and subsequent anxiety, while widowed participants exhibited a heightened impact of depression on subsequent depression. These results underscore the importance of early identification and integrative interventions aimed at addressing both anxiety and depression to mitigate subsequent symptoms in BSDs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depressive symptoms as a heterogeneous and constantly evolving dynamical system: Idiographic depressive symptom networks of rapid symptom changes among persons with major depressive disorder. 抑郁症状是一个异质的、不断演变的动态系统:重度抑郁症患者症状快速变化的图像抑郁症状网络。
Pub Date : 2024-02-01 DOI: 10.1037/abn0000884
Matthew D Nemesure, Amanda C Collins, George D Price, Tess Z Griffin, Arvind Pillai, Subigya Nepal, Michael V Heinz, Damien Lekkas, Andrew T Campbell, Nicholas C Jacobson

Major depressive disorder (MDD) is conceptualized by individual symptoms occurring most of the day for at least two weeks. Despite this operationalization, MDD is highly variable with persons showing greater variation within and across days. Moreover, MDD is highly heterogeneous, varying considerably across people in both function and form. Recent efforts have examined MDD heterogeneity byinvestigating how symptoms influence one another over time across individuals in a system; however, these efforts have assumed that symptom dynamics are static and do not dynamically change over time. Nevertheless, it is possible that individual MDD system dynamics change continuously across time. Participants (N = 105) completed ratings of MDD symptoms three times a day for 90 days, and we conducted time varying vector autoregressive models to investigate the idiographic symptom networks. We then illustrated this finding with a case series of five persons with MDD. Supporting prior research, results indicate there is high heterogeneity across persons as individual network composition is unique from person to person. In addition, for most persons, individual symptom networks change dramatically across the 90 days, as evidenced by 86% of individuals experiencing at least one change in their most influential symptom and the median number of shifts being 3 over the 90 days. Additionally, most individuals had at least one symptom that acted as both the most and least influential symptom at any given point over the 90-day period. Our findings offer further insight into short-term symptom dynamics, suggesting that MDD is heterogeneous both across and within persons over time. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

重度抑郁障碍(MDD)的概念是个人症状在一天中的大部分时间出现,持续至少两周。尽管采用了这种操作方法,但重度抑郁障碍的变化很大,患者在一天之内和一天之间的变化更大。此外,MDD 还具有高度异质性,在功能和形式上因人而异。最近的研究通过调查症状如何随着时间的推移在一个系统中的不同个体之间相互影响,对 MDD 的异质性进行了研究;然而,这些研究假定症状的动态变化是静态的,不会随着时间的推移而发生动态变化。然而,MDD 系统中个体的动态变化有可能随着时间的推移而不断变化。参与者(N = 105)在 90 天内每天三次完成对 MDD 症状的评分,我们采用时变向量自回归模型来研究特异性症状网络。然后,我们用五名 MDD 患者的病例系列说明了这一发现。与之前的研究结果一致,研究结果表明,由于个体网络构成因人而异,因此不同患者之间存在高度异质性。此外,对于大多数人来说,个人症状网络在 90 天内会发生巨大变化,86% 的人在其最有影响力的症状上至少发生过一次变化,90 天内变化的中位数为 3 次,这就证明了这一点。此外,大多数人在 90 天内的任何时候都至少有一种症状既是影响最大的症状,也是影响最小的症状。我们的研究结果进一步揭示了短期症状的动态变化,表明随着时间的推移,多发性抑郁症在不同个体之间和个体内部都存在异质性。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
{"title":"Depressive symptoms as a heterogeneous and constantly evolving dynamical system: Idiographic depressive symptom networks of rapid symptom changes among persons with major depressive disorder.","authors":"Matthew D Nemesure, Amanda C Collins, George D Price, Tess Z Griffin, Arvind Pillai, Subigya Nepal, Michael V Heinz, Damien Lekkas, Andrew T Campbell, Nicholas C Jacobson","doi":"10.1037/abn0000884","DOIUrl":"10.1037/abn0000884","url":null,"abstract":"<p><p>Major depressive disorder (MDD) is conceptualized by individual symptoms occurring most of the day for at least two weeks. Despite this operationalization, MDD is highly variable with persons showing greater variation within and across days. Moreover, MDD is highly heterogeneous, varying considerably across people in both function and form. Recent efforts have examined MDD heterogeneity byinvestigating how symptoms influence one another over time across individuals in a system; however, these efforts have assumed that symptom dynamics are static and do not dynamically change over time. Nevertheless, it is possible that individual MDD system dynamics change continuously across time. Participants (N = 105) completed ratings of MDD symptoms three times a day for 90 days, and we conducted time varying vector autoregressive models to investigate the idiographic symptom networks. We then illustrated this finding with a case series of five persons with MDD. Supporting prior research, results indicate there is high heterogeneity across persons as individual network composition is unique from person to person. In addition, for most persons, individual symptom networks change dramatically across the 90 days, as evidenced by 86% of individuals experiencing at least one change in their most influential symptom and the median number of shifts being 3 over the 90 days. Additionally, most individuals had at least one symptom that acted as both the most and least influential symptom at any given point over the 90-day period. Our findings offer further insight into short-term symptom dynamics, suggesting that MDD is heterogeneous both across and within persons over time. (PsycInfo Database Record (c) 2024 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11002496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139565461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supplemental Material for Longitudinal Dynamics Between Anxiety and Depression in Bipolar Spectrum Disorders 双相情感障碍中焦虑与抑郁之间的纵向动态关系》补充材料
Pub Date : 2024-01-04 DOI: 10.1037/abn0000890.supp
{"title":"Supplemental Material for Longitudinal Dynamics Between Anxiety and Depression in Bipolar Spectrum Disorders","authors":"","doi":"10.1037/abn0000890.supp","DOIUrl":"https://doi.org/10.1037/abn0000890.supp","url":null,"abstract":"","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139385012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altered attentional processing of facial expression features in severe alcohol use disorder: An eye-tracking study. 严重酒精使用障碍患者面部表情特征的注意加工改变:一项眼动追踪研究。
Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.1037/abn0000868
Arthur Pabst, Zoé Bollen, Nicolas Masson, Mado Gautier, Christophe Geus, Pierre Maurage

Social cognition impairments, and notably emotional facial expression (EFE) recognition difficulties, as well as their functional and clinical correlates, are increasingly documented in severe alcohol use disorder (SAUD). However, insights into their underlying mechanisms are lacking. Here, we tested if SAUD was associated with alterations in the attentional processing of EFEs. In a preregistered study, 40 patients with SAUD and 40 healthy controls (HCs) had to identify the emotional expression conveyed by faces while having their gaze recorded by an eye-tracker. We assessed indices of initial (first fixation locations) and later (number of fixations and dwell-time) attention with reference to regions of interest corresponding to the eyes, mouth, and nose, which carry key information for EFE recognition. We centrally found that patients had less first fixations to key facial features in general, as well as less fixations and dwell time to the eyes specifically, relative to the rest of the face, compared to controls. These effects were invariant across emotional expressions. Additional exploratory analyses revealed that patients with SAUD had a less structured viewing pattern than controls. These results offer novel, direct, evidence that patients with SAUD's socioaffective difficulties already emerge at the facial attentional processing stage, along with precisions regarding the nature and generalizability of the effects. Potential implications for the mechanistic conceptualization and treatment of social cognition difficulties in SAUD are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

社会认知障碍,尤其是情绪面部表情(EFE)识别困难,以及它们的功能和临床相关性,在严重酒精使用障碍(SAUD)中越来越多地被记录下来。然而,缺乏对其潜在机制的深入了解。在这里,我们测试了SAUD是否与efe注意加工的改变有关。在一项预先登记的研究中,40名沙特阿拉伯患者和40名健康对照者(hc)必须识别面部传达的情绪表情,同时用眼动仪记录他们的目光。我们评估了初始(第一次注视位置)和后期(注视次数和停留时间)注意指标,参考了与眼睛、嘴巴和鼻子相对应的感兴趣区域,这些区域携带着EFE识别的关键信息。我们集中发现,与对照组相比,患者对主要面部特征的第一次注视较少,特别是对眼睛的注视和停留时间也较少,相对于面部的其他部分。这些影响在各种情绪表达中都是不变的。另外的探索性分析显示,与对照组相比,沙特阿拉伯患者的结构化观看模式更少。这些结果提供了新颖、直接的证据,表明患有沙特阿拉伯社会情感困难的患者已经出现在面部注意处理阶段,以及有关影响的性质和普遍性的准确性。讨论了沙特阿拉伯社会认知困难的机制概念化和治疗的潜在影响。(PsycInfo数据库记录(c) 2023 APA,版权所有)。
{"title":"Altered attentional processing of facial expression features in severe alcohol use disorder: An eye-tracking study.","authors":"Arthur Pabst, Zoé Bollen, Nicolas Masson, Mado Gautier, Christophe Geus, Pierre Maurage","doi":"10.1037/abn0000868","DOIUrl":"10.1037/abn0000868","url":null,"abstract":"<p><p>Social cognition impairments, and notably emotional facial expression (EFE) recognition difficulties, as well as their functional and clinical correlates, are increasingly documented in severe alcohol use disorder (SAUD). However, insights into their underlying mechanisms are lacking. Here, we tested if SAUD was associated with alterations in the attentional processing of EFEs. In a preregistered study, 40 patients with SAUD and 40 healthy controls (HCs) had to identify the emotional expression conveyed by faces while having their gaze recorded by an eye-tracker. We assessed indices of initial (first fixation locations) and later (number of fixations and dwell-time) attention with reference to regions of interest corresponding to the eyes, mouth, and nose, which carry key information for EFE recognition. We centrally found that patients had less first fixations to key facial features in general, as well as less fixations and dwell time to the eyes specifically, relative to the rest of the face, compared to controls. These effects were invariant across emotional expressions. Additional exploratory analyses revealed that patients with SAUD had a less structured viewing pattern than controls. These results offer novel, direct, evidence that patients with SAUD's socioaffective difficulties already emerge at the facial attentional processing stage, along with precisions regarding the nature and generalizability of the effects. Potential implications for the mechanistic conceptualization and treatment of social cognition difficulties in SAUD are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92158039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do emotion regulation difficulties in depression extend to social context? Everyday interpersonal emotion regulation in current and remitted major depressive disorder. 抑郁症的情绪调节困难会延伸到社会环境吗?重度抑郁障碍的日常人际情绪调节。
Pub Date : 2024-01-01 Epub Date: 2023-12-07 DOI: 10.1037/abn0000877
Daphne Y Liu, Michael J Strube, Renee J Thompson

Individuals with major depressive disorder (MDD) have difficulties regulating emotion on their own. As people also use social resources to regulate emotion (i.e., interpersonal emotion regulation [IER]), we examined whether these difficulties extend to IER in current and remitted MDD compared to those with no psychiatric disorders (i.e., controls). Adults with current MDD (n = 48), remitted MDD (n = 80), and controls (n = 87) assessed via diagnostic interviewing completed 2-week experience sampling, reporting on how frequently (IER frequency), from whom (sharing partners), and why (IER goals) they sought IER; how the sharing partners responded (sharing partner's extrinsic IER strategies and warmth); and how their feelings about the problem and the sharing partner changed following IER (IER outcomes). Using multilevel modeling, the current-MDD group did not differ from controls in IER frequency and sharing partners, but the current-MDD group demonstrated a more mixed (albeit generally adaptive) profile of received IER strategies and benefited similarly or more from certain IER strategies than the other two groups, suggesting that IER may be a promising avenue for effective emotion regulation in current MDD. The remitted-MDD group sought IER most frequently and demonstrated the most adaptive profile of received IER strategies, and they and the current-MDD group reported seeking more types of IER goals than controls. People with remitted MDD seem highly motivated to pursue IER support and their pursuit takes place in particularly supportive social contexts. Research is needed to examine mechanisms driving these group differences and how IER predicts the course of MDD. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

患有重度抑郁症(MDD)的人很难自己调节情绪。由于人们也使用社会资源来调节情绪(即人际情绪调节[IER]),我们研究了与没有精神障碍的人(即对照组)相比,这些困难是否会扩展到当前和缓解的重度抑郁症患者的情绪调节。目前患有重度抑郁症(n = 48)、已缓解重度抑郁症(n = 80)和对照组(n = 87)的成年人通过诊断性访谈进行评估,他们完成了为期2周的经验抽样,报告了他们寻求重度抑郁症的频率(IER频率)、从谁那里(共享伴侣)以及为什么(IER目标);分享伙伴如何回应(分享伙伴的外在IER策略和温暖度);以及他们对问题和分享伴侣的感受在IER (IER结果)之后是如何变化的。使用多层模型,当前MDD组在情感情感频率和分享伴侣方面与对照组没有差异,但当前MDD组在接受情感情感策略方面表现出更混合的(尽管通常是适应性的)特征,并且从某些情感情感策略中获得的收益与其他两组相似或更多,这表明情感情感可能是当前MDD中有效情绪调节的有希望的途径。缓解mdd组最频繁地寻求IER,并展示了所接受的IER策略的最适应性,并且他们和当前mdd组报告寻求比对照组更多类型的IER目标。抑郁症缓解的人似乎有很高的动机去寻求情感上的支持,他们的追求发生在特别支持性的社会环境中。需要研究驱动这些群体差异的机制,以及IER如何预测重度抑郁症的病程。(PsycInfo数据库记录(c) 2023 APA,版权所有)。
{"title":"Do emotion regulation difficulties in depression extend to social context? Everyday interpersonal emotion regulation in current and remitted major depressive disorder.","authors":"Daphne Y Liu, Michael J Strube, Renee J Thompson","doi":"10.1037/abn0000877","DOIUrl":"10.1037/abn0000877","url":null,"abstract":"<p><p>Individuals with major depressive disorder (MDD) have difficulties regulating emotion on their own. As people also use social resources to regulate emotion (i.e., interpersonal emotion regulation [IER]), we examined whether these difficulties extend to IER in current and remitted MDD compared to those with no psychiatric disorders (i.e., controls). Adults with current MDD (<i>n</i> = 48), remitted MDD (<i>n</i> = 80), and controls (<i>n</i> = 87) assessed via diagnostic interviewing completed 2-week experience sampling, reporting on how frequently (IER frequency), from whom (sharing partners), and why (IER goals) they sought IER; how the sharing partners responded (sharing partner's extrinsic IER strategies and warmth); and how their feelings about the problem and the sharing partner changed following IER (IER outcomes). Using multilevel modeling, the current-MDD group did not differ from controls in IER frequency and sharing partners, but the current-MDD group demonstrated a more mixed (albeit generally adaptive) profile of received IER strategies and benefited similarly or more from certain IER strategies than the other two groups, suggesting that IER may be a promising avenue for effective emotion regulation in current MDD. The remitted-MDD group sought IER most frequently and demonstrated the most adaptive profile of received IER strategies, and they and the current-MDD group reported seeking more types of IER goals than controls. People with remitted MDD seem highly motivated to pursue IER support and their pursuit takes place in particularly supportive social contexts. Research is needed to examine mechanisms driving these group differences and how IER predicts the course of MDD. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive risk phenotyping to predict mood symptoms in adolescence. 神经认知风险表型预测青少年情绪症状。
Pub Date : 2024-01-01 Epub Date: 2023-12-07 DOI: 10.1037/abn0000866
Roselinde H Kaiser, Amelia D Moser, Chiara Neilson, Jenna Jones, Elena C Peterson, Luke Ruzic, Benjamin M Rosenberg, Christina M Hough, Christina Sandman, Christopher D Schneck, David J Miklowitz

Predicting mood disorders in adolescence is a challenge that motivates research to identify neurocognitive predictors of symptom expression and clinical profiles. This study used machine learning to test whether neurocognitive variables predicted future manic or anhedonic symptoms in two adolescent samples risk-enriched for lifetime mood disorders (Sample 1, n = 73, ages = 13-25, M [SD] = 19.22 [2.49] years, 68% lifetime mood disorder) or familial mood disorders (Sample 2, n = 154, ages = 13-21, M [SD] = 16.46 [1.95] years, 62% first-degree family history of mood disorder). Participants completed cognitive testing and functional magnetic resonance imaging at baseline, for behavioral and neural measures of reward processing and executive functioning. Next, participants completed a daily diary procedure for 8-16 weeks. Penalized mixed-effects models identified neurocognitive predictors of future mood symptoms and stress-reactive changes in mood symptoms. Results included the following. In both samples, adolescents showing ventral corticostriatal reward hyposensitivity and lower reward performance reported more severe stress-reactive anhedonia. Poorer executive functioning behavior was associated with heightened anhedonia overall in Sample 1, but lower stress-reactive anhedonia in both samples. In Sample 1, adolescents showing ventral corticostriatal reward hypersensitivity and poorer executive functioning reported more severe stress-reactive manic symptoms. Clustering analyses identified, and replicated, five neurocognitive subgroups. Adolescents characterized by neural or behavioral reward hyposensitivities together with average-to-poor executive functioning reported unipolar symptom profiles. Adolescents showing neural reward hypersensitivity together with poor behavioral executive functioning reported a bipolar symptom profile (Sample 1 only). Together, neurocognitive phenotypes may hold value for predicting symptom expression and profiles of mood pathology. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

预测青少年情绪障碍是一项挑战,促使研究确定症状表达和临床概况的神经认知预测因子。本研究使用机器学习来测试神经认知变量是否能预测两名终生情绪障碍(样本1,n = 73,年龄= 13-25,M [SD] = 19.22[2.49]年,68%终生情绪障碍)或家族性情绪障碍(样本2,n = 154,年龄= 13-21,M [SD] = 16.46[1.95]年,62%一级情绪障碍家族史)高风险青少年样本的未来躁狂或快感缺乏症状。参与者在基线时完成了认知测试和功能性磁共振成像,用于奖励处理和执行功能的行为和神经测量。接下来,参与者完成了8-16周的每日日记程序。惩罚混合效应模型确定了未来情绪症状的神经认知预测因子和情绪症状的应激反应变化。结果包括以下内容。在这两个样本中,表现出腹侧皮质纹状体奖励低敏感性和较低奖励表现的青少年报告了更严重的应激反应性快感缺乏。在样本1中,较差的执行功能行为与总体快感缺乏症有关,但在两个样本中,压力反应性快感缺乏症较低。在样本1中,表现出腹侧皮质纹状体奖励超敏反应和较差执行功能的青少年报告了更严重的应激反应性躁狂症状。聚类分析确定并复制了五个神经认知亚群。以神经或行为奖励低敏感性为特征的青少年以及平均到较差的执行功能报告了单极症状特征。表现出神经奖励超敏反应和行为执行功能差的青少年报告了双相症状(仅限样本1)。总之,神经认知表型可能对预测症状表达和情绪病理概况具有价值。(PsycInfo数据库记录(c) 2023 APA,版权所有)。
{"title":"Neurocognitive risk phenotyping to predict mood symptoms in adolescence.","authors":"Roselinde H Kaiser, Amelia D Moser, Chiara Neilson, Jenna Jones, Elena C Peterson, Luke Ruzic, Benjamin M Rosenberg, Christina M Hough, Christina Sandman, Christopher D Schneck, David J Miklowitz","doi":"10.1037/abn0000866","DOIUrl":"10.1037/abn0000866","url":null,"abstract":"<p><p>Predicting mood disorders in adolescence is a challenge that motivates research to identify neurocognitive predictors of symptom expression and clinical profiles. This study used machine learning to test whether neurocognitive variables predicted future manic or anhedonic symptoms in two adolescent samples risk-enriched for lifetime mood disorders (Sample 1, <i>n</i> = 73, ages = 13-25, <i>M</i> [<i>SD</i>] = 19.22 [2.49] years, 68% lifetime mood disorder) or familial mood disorders (Sample 2, <i>n</i> = 154, ages = 13-21, <i>M</i> [<i>SD</i>] = 16.46 [1.95] years, 62% first-degree family history of mood disorder). Participants completed cognitive testing and functional magnetic resonance imaging at baseline, for behavioral and neural measures of reward processing and executive functioning. Next, participants completed a daily diary procedure for 8-16 weeks. Penalized mixed-effects models identified neurocognitive predictors of future mood symptoms and stress-reactive changes in mood symptoms. Results included the following. In both samples, adolescents showing ventral corticostriatal reward hyposensitivity and lower reward performance reported more severe stress-reactive anhedonia. Poorer executive functioning behavior was associated with heightened anhedonia overall in Sample 1, but lower stress-reactive anhedonia in both samples. In Sample 1, adolescents showing ventral corticostriatal reward hypersensitivity and poorer executive functioning reported more severe stress-reactive manic symptoms. Clustering analyses identified, and replicated, five neurocognitive subgroups. Adolescents characterized by neural or behavioral reward hyposensitivities together with average-to-poor executive functioning reported unipolar symptom profiles. Adolescents showing neural reward hypersensitivity together with poor behavioral executive functioning reported a bipolar symptom profile (Sample 1 only). Together, neurocognitive phenotypes may hold value for predicting symptom expression and profiles of mood pathology. (PsycInfo Database Record (c) 2023 APA, all rights reserved).</p>","PeriodicalId":73914,"journal":{"name":"Journal of psychopathology and clinical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10752243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of psychopathology and clinical science
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1