首页 > 最新文献

Journal of women's health and development最新文献

英文 中文
Effective Tumor Control Following Re-Irradiation Combined with Superficial Hyperthermia of Inoperable, Locally Recurrent Breast Cancers 再照射联合浅表热疗对不能手术的局部复发乳腺癌的有效肿瘤控制
Pub Date : 2022-01-01 DOI: 10.26502/fjwhd.2644-28840076
Notter Markus, Thomsen Ar, Vaupel P
Inoperable, locally Recurrent Breast Cancer (LRBC) in previously irradiated regions is a challenging disease to manage. Superficial Hyperthermia (sHT) in combination with Re-Irradiation (re-RT) offers an effective local tumor control with a total re-RT dose of 20 Gy. The low toxicity enables the application of repeated re-irradiations, especially in recurrent lymphangiosis carcinomatosa. This technology can also be applied with other superficial tumor types, e.g., in primary or radiation-associated angiosarcoma or skin metastasis.
不能手术,局部复发乳腺癌(LRBC)在以前的放疗区域是一个具有挑战性的疾病管理。浅表热疗(sHT)联合再照射(re-RT)提供了有效的局部肿瘤控制,总再照射剂量为20 Gy。低毒性使反复再照射的应用,特别是在复发性淋巴管病癌。该技术也可以应用于其他浅表肿瘤类型,例如原发性或辐射相关血管肉瘤或皮肤转移。
{"title":"Effective Tumor Control Following Re-Irradiation Combined with Superficial Hyperthermia of Inoperable, Locally Recurrent Breast Cancers","authors":"Notter Markus, Thomsen Ar, Vaupel P","doi":"10.26502/fjwhd.2644-28840076","DOIUrl":"https://doi.org/10.26502/fjwhd.2644-28840076","url":null,"abstract":"Inoperable, locally Recurrent Breast Cancer (LRBC) in previously irradiated regions is a challenging disease to manage. Superficial Hyperthermia (sHT) in combination with Re-Irradiation (re-RT) offers an effective local tumor control with a total re-RT dose of 20 Gy. The low toxicity enables the application of repeated re-irradiations, especially in recurrent lymphangiosis carcinomatosa. This technology can also be applied with other superficial tumor types, e.g., in primary or radiation-associated angiosarcoma or skin metastasis.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79662198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surviving Tactics of Medical Interns Countering Long Working Hours: A Systematic Review 医疗实习生应对长时间工作的生存策略:系统回顾
Pub Date : 2022-01-01 DOI: 10.26502/fjwhd.2644-28840096
Shamaila Manzoor, Idrees Anwar, Aisha Rafi
{"title":"Surviving Tactics of Medical Interns Countering Long Working Hours: A Systematic Review","authors":"Shamaila Manzoor, Idrees Anwar, Aisha Rafi","doi":"10.26502/fjwhd.2644-28840096","DOIUrl":"https://doi.org/10.26502/fjwhd.2644-28840096","url":null,"abstract":"","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"143 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73913949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gynaecological Health of Women Attending Hospital in Oil City of Port Harcourt in the Niger Delta Region of Nigeria 尼日利亚尼日尔三角洲地区哈科特港油城住院妇女的妇科健康
Pub Date : 2022-01-01 DOI: 10.26502/fjwhd.2644-28840080
Felix M Onyije, Ajuluchukwu Azubuike Ngokere, Aloysius Ebi Ligha, Godwin Ovie Avwioro, O. Mgbere
Introduction: Increasingly, residents of the Niger Delta region of Nigeria are reporting health impacts that they believe are linked to environmental pollutions from oil and gas activities. Hence, the objective of this study was to assess the gynaecological health of women in the Oil City of Port Harcourt in the Niger Delta Region of Nigeria. Methods: Data used for this study (n=697) were obtained from the Rivers State University Teaching Hospital (RSUTH) in Port Harcourt, Nigeria. The J Women’s Health Dev 2022; 5 (1): 097-108 DOI: 10.26502/fjwhd.2644-28840080 Journal of Women’s Health and Development Volume 5 No 1 – March 2022 98 patients had partial or total hysterectomy or diagnosed of gynaecological lesion. Data obtained were subjected to both descriptive and inferential statistics using SAS 9.4 version (SAS Institute, Cary, NC, USA). Results: The distribution of the gynaecological lesions differed significantly (p<0.001) by year of diagnosis, developmental stage, age category and types of lesion. Leiomyoma was the highest number of lesions identified (56.0%, n=390), followed by ovarian cyst (10.0%, n=70) and retained product of conception (8.0%, n=56). Women of age group 30-39 years and 40-49 years had the highest number of lesions during the study period with a range of 2171% and 17-34 %, respectively. Conclusion: The prevalence and characteristics of gynaecological lesions in our study sample point to the potential public health consequences, and strong need for creation of awareness campaigns and general health assessment in the Niger Delta region of Nigeria.
导言:尼日利亚尼日尔三角洲地区的居民越来越多地报告他们认为与石油和天然气活动造成的环境污染有关的健康影响。因此,本研究的目的是评估尼日利亚尼日尔三角洲地区石油城市哈科特港妇女的妇科健康状况。方法:本研究使用的数据(n=697)来自尼日利亚哈科特港的河流州立大学教学医院(RSUTH)。《妇女健康发展2022》;[5] (1): 097-108 DOI: 10.26502/fjwhd.]妇女健康与发展杂志第5卷第1期- 2022年3月98例患者部分或全部切除子宫或诊断为妇科病变。使用SAS 9.4版本(SAS Institute, Cary, NC, USA)对获得的数据进行描述性和推断性统计。结果:妇科病变在诊断年份、发育阶段、年龄分型、病变类型上的分布差异有统计学意义(p<0.001)。发现的病变最多的是平滑肌瘤(56.0%,n=390),其次是卵巢囊肿(10.0%,n=70)和受孕产物残留(8.0%,n=56)。30-39岁和40-49岁的女性在研究期间的病变数量最多,分别为2171%和17- 34%。结论:在我们的研究样本中,妇科病变的患病率和特征表明了潜在的公共卫生后果,以及在尼日利亚尼日尔三角洲地区开展宣传运动和一般健康评估的强烈需要。
{"title":"Gynaecological Health of Women Attending Hospital in Oil City of Port Harcourt in the Niger Delta Region of Nigeria","authors":"Felix M Onyije, Ajuluchukwu Azubuike Ngokere, Aloysius Ebi Ligha, Godwin Ovie Avwioro, O. Mgbere","doi":"10.26502/fjwhd.2644-28840080","DOIUrl":"https://doi.org/10.26502/fjwhd.2644-28840080","url":null,"abstract":"Introduction: Increasingly, residents of the Niger Delta region of Nigeria are reporting health impacts that they believe are linked to environmental pollutions from oil and gas activities. Hence, the objective of this study was to assess the gynaecological health of women in the Oil City of Port Harcourt in the Niger Delta Region of Nigeria. Methods: Data used for this study (n=697) were obtained from the Rivers State University Teaching Hospital (RSUTH) in Port Harcourt, Nigeria. The J Women’s Health Dev 2022; 5 (1): 097-108 DOI: 10.26502/fjwhd.2644-28840080 Journal of Women’s Health and Development Volume 5 No 1 – March 2022 98 patients had partial or total hysterectomy or diagnosed of gynaecological lesion. Data obtained were subjected to both descriptive and inferential statistics using SAS 9.4 version (SAS Institute, Cary, NC, USA). Results: The distribution of the gynaecological lesions differed significantly (p<0.001) by year of diagnosis, developmental stage, age category and types of lesion. Leiomyoma was the highest number of lesions identified (56.0%, n=390), followed by ovarian cyst (10.0%, n=70) and retained product of conception (8.0%, n=56). Women of age group 30-39 years and 40-49 years had the highest number of lesions during the study period with a range of 2171% and 17-34 %, respectively. Conclusion: The prevalence and characteristics of gynaecological lesions in our study sample point to the potential public health consequences, and strong need for creation of awareness campaigns and general health assessment in the Niger Delta region of Nigeria.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83776607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors and Referral Rates for Urinary Tract Infection in Pregnant Mothers of Southwest Guatemala. 危地马拉西南部孕妇尿路感染的危险因素和转诊率。
Pub Date : 2021-12-01 Epub Date: 2021-10-09
Michael Miller, Molly Lamb, Claudia Rivera, Saskia Bunge Montes, Andrea Jimenez-Zambrano, Antonio Bolanos, Edwin Asturias, Stephen Berman, Margo S Harrison
{"title":"Risk Factors and Referral Rates for Urinary Tract Infection in Pregnant Mothers of Southwest Guatemala.","authors":"Michael Miller,&nbsp;Molly Lamb,&nbsp;Claudia Rivera,&nbsp;Saskia Bunge Montes,&nbsp;Andrea Jimenez-Zambrano,&nbsp;Antonio Bolanos,&nbsp;Edwin Asturias,&nbsp;Stephen Berman,&nbsp;Margo S Harrison","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"4 4","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39833753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors and Referral Rates for Urinary Tract Infection in Pregnant Mothers of Southwest Guatemala 危地马拉西南部孕妇尿路感染的危险因素和转诊率
Pub Date : 2021-10-09 DOI: 10.26502/fjwhd.2644-28840065
Michael Miller, M. Lamb, Claudia Rivera, Saskia Bunge Montes, Andrea Jimenez-Zambrano, Antonio Bolaños, E. Asturias, S. Berman, Margo S. Harrison
Urinary tract infections (UTIs) affect one in four women in lowand middleincome countries and are associated with adverse maternal and neonatal outcomes [1, 2]. In Latin America, the prevalence of UTI is estimated to be 23–31%, yet data in this region is sparse [3]. The objective of this analysis was to understand the prevalence, referral rates, and risk factors associated with UTIs in the Southwest Trifinio region of Guatemala.
在中低收入国家,四分之一的妇女受到尿路感染(uti)的影响,并与孕产妇和新生儿的不良结局有关[1,2]。在拉丁美洲,尿路感染的患病率估计为23-31%,但该地区的数据很少。本分析的目的是了解危地马拉特里菲尼奥西南部地区与尿路感染相关的患病率、转诊率和危险因素。
{"title":"Risk Factors and Referral Rates for Urinary Tract Infection in Pregnant Mothers of Southwest Guatemala","authors":"Michael Miller, M. Lamb, Claudia Rivera, Saskia Bunge Montes, Andrea Jimenez-Zambrano, Antonio Bolaños, E. Asturias, S. Berman, Margo S. Harrison","doi":"10.26502/fjwhd.2644-28840065","DOIUrl":"https://doi.org/10.26502/fjwhd.2644-28840065","url":null,"abstract":"Urinary tract infections (UTIs) affect one in four women in lowand middleincome countries and are associated with adverse maternal and neonatal outcomes [1, 2]. In Latin America, the prevalence of UTI is estimated to be 23–31%, yet data in this region is sparse [3]. The objective of this analysis was to understand the prevalence, referral rates, and risk factors associated with UTIs in the Southwest Trifinio region of Guatemala.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"18 1","pages":"110 - 112"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83043360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DE-T1 On The Blastocyst Obtained Rate and Live Births Rates in Women Receiving IVF-ET Treatment DE-T1对接受IVF-ET治疗的妇女囊胚获得率和活产率的影响
Pub Date : 2021-10-01 DOI: 10.21203/rs.3.rs-900217/v1
H. Shao, Yoji Yamaguchi, Toshiaki Nozaki, Lina Bai, Xi Dong, Dongzi Yang, Shuang Jiao, J. Otsuki, S. Kokeguchi, M. Shiotani
BackgroundOur objective was to retrospectively analyze the influence of DE-T1, a type of amino-polysaccharide extracted from dandelions, on the rates of blastocysts obtained and live births in women undergoing IVF-ET treatment.MethodsThis was a retrospective cohort study, conducting a total of 1014 patients over the age of 30, who received IVF treatment at Hanabusa Women’s clinic from Aug. 1, 2012 to Feb. 29, 2020. The patients were divided into two groups, based on their own choice regarding DE-T1 supplementation, which is available as over the counter medicine at the Clinic. The two groups’ overall rates of blastocysts obtained were compared and the rates of blastocysts obtained in patients with different ages and Anti-Mullerian hormone (AMH) levels were also compared using an Intention-to-treat (ITT) analysis. Among the patients who completed embryo transfers (ET), the live birth rate was compared between the supplementation group and the non-supplementation group using a Chi-squared test.ResultsThe blastocyst obtained rate in the supplementation group was 75.98%, which was significantly higher than that of 57.28% in the non-supplementation group (P=2.4×109). The blastocyst obtained rate across the range of ages in the supplementation group were significantly higher than those of the non-supplementation group (≥30 and <35 years of age: 90.97% vs 74.32%, P=0.001;≥35 and <40 years of age: 82.40% vs 69.79%, P= 0.010; ≥40 and <43 years of age: 72.90% vs 52.11%, P=0.002; ≥43 years of age: 53.29% vs 22.95%, P= 5.7×105). The blastocyst obtained rate for both AMH levels in the supplementation group were significantly higher than those of the non-supplementation group (AMH≤1.1: 56.47% vs 40.44%, P=0.002; AMH> 1.1: 88.48% vs 71.08%, P=2.52×107). The live birth rate of the supplementation group was significantly higher than that of the non-supplementation group (57.53% vs. 40.0%, P=0.045).ConclusionDE-T1 supplementation might be an influence on improving the blastocyst obtained rate and live birth rates in women receiving IVF-ET treatment. DE-T1 supplementation might be of benefit to women of different ages and AMH levels.
我们的目的是回顾性分析DE-T1(一种从蒲公英中提取的氨基多糖)对接受IVF-ET治疗的妇女获得囊胚率和活产率的影响。方法回顾性队列研究,纳入2012年8月1日至2020年2月29日在Hanabusa妇女诊所接受体外受精治疗的1014例30岁以上患者。患者根据自己对DE-T1补充的选择分为两组,DE-T1补充是诊所提供的非处方药物。比较两组的囊胚总获得率,并采用意向治疗(ITT)分析比较不同年龄患者的囊胚获得率和抗苗勒管激素(AMH)水平。在完成胚胎移植(ET)的患者中,使用卡方检验比较补充组和未补充组的活产率。结果添加组的囊胚获得率为75.98%,显著高于未添加组的57.28% (P=2.4×109)。全年龄范围内,添加组囊胚获得率显著高于未添加组(≥30和1.1:88.48% vs 71.08%, P=2.52×107)。添加组的活产率显著高于未添加组(57.53% vs. 40.0%, P=0.045)。结论补充de - t1可能对提高IVF-ET治疗妇女的囊胚获得率和活产率有影响。补充DE-T1可能对不同年龄和AMH水平的女性有益。
{"title":"DE-T1 On The Blastocyst Obtained Rate and Live Births Rates in Women Receiving IVF-ET Treatment","authors":"H. Shao, Yoji Yamaguchi, Toshiaki Nozaki, Lina Bai, Xi Dong, Dongzi Yang, Shuang Jiao, J. Otsuki, S. Kokeguchi, M. Shiotani","doi":"10.21203/rs.3.rs-900217/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-900217/v1","url":null,"abstract":"\u0000 Background\u0000\u0000Our objective was to retrospectively analyze the influence of DE-T1, a type of amino-polysaccharide extracted from dandelions, on the rates of blastocysts obtained and live births in women undergoing IVF-ET treatment.\u0000Methods\u0000\u0000This was a retrospective cohort study, conducting a total of 1014 patients over the age of 30, who received IVF treatment at Hanabusa Women’s clinic from Aug. 1, 2012 to Feb. 29, 2020. The patients were divided into two groups, based on their own choice regarding DE-T1 supplementation, which is available as over the counter medicine at the Clinic. The two groups’ overall rates of blastocysts obtained were compared and the rates of blastocysts obtained in patients with different ages and Anti-Mullerian hormone (AMH) levels were also compared using an Intention-to-treat (ITT) analysis. Among the patients who completed embryo transfers (ET), the live birth rate was compared between the supplementation group and the non-supplementation group using a Chi-squared test.\u0000Results\u0000\u0000The blastocyst obtained rate in the supplementation group was 75.98%, which was significantly higher than that of 57.28% in the non-supplementation group (P=2.4×109). The blastocyst obtained rate across the range of ages in the supplementation group were significantly higher than those of the non-supplementation group (≥30 and <35 years of age: 90.97% vs 74.32%, P=0.001;≥35 and <40 years of age: 82.40% vs 69.79%, P= 0.010; ≥40 and <43 years of age: 72.90% vs 52.11%, P=0.002; ≥43 years of age: 53.29% vs 22.95%, P= 5.7×105). The blastocyst obtained rate for both AMH levels in the supplementation group were significantly higher than those of the non-supplementation group (AMH≤1.1: 56.47% vs 40.44%, P=0.002; AMH> 1.1: 88.48% vs 71.08%, P=2.52×107). The live birth rate of the supplementation group was significantly higher than that of the non-supplementation group (57.53% vs. 40.0%, P=0.045).\u0000Conclusion\u0000\u0000DE-T1 supplementation might be an influence on improving the blastocyst obtained rate and live birth rates in women receiving IVF-ET treatment. DE-T1 supplementation might be of benefit to women of different ages and AMH levels.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80594061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Secondary Analysis of the LILAC Study Regarding Cesarean Birth by Maternal Request in Women Living with HIV. LILAC研究中HIV感染者产妇要求剖宫产的二次分析。
Pub Date : 2021-06-16 DOI: 10.26502/fjwhd.2644-28840062
Margo S Harrison

Background: Latin America has the highest regional average cesarean birth rates. One potential driver is cesarean birth by maternal request (CBMR).

Methods: We analyzed of a large prospective cohort study of HIV-infected women in six Latin American countries.

Results: Comparisons were made between women who chose CBMR (n = 38) and women with a medical indication for cesarean (n = 683). The only variable associated with CBMR was onset of labor (AOR 0.3 [0.1,0.9], p = 0.04).

Conslusion: Spontaneous labor reduced the likelihood of a woman living with HIV to pursue CBMR in a large Latin American cohort.

背景:拉丁美洲是剖宫产平均出生率最高的地区。一个潜在的驱动因素是产妇要求剖宫产(CBMR)。方法:我们分析了6个拉丁美洲国家的hiv感染妇女的大型前瞻性队列研究。结果:比较了选择CBMR的妇女(n = 38)和有医学指征的剖宫产妇女(n = 683)。与CBMR相关的唯一变量是分娩开始时间(AOR为0.3 [0.1,0.9],p = 0.04)。结论:在拉丁美洲的一个大型队列中,自然分娩降低了感染艾滋病毒的妇女进行CBMR的可能性。
{"title":"A Secondary Analysis of the LILAC Study Regarding Cesarean Birth by Maternal Request in Women Living with HIV.","authors":"Margo S Harrison","doi":"10.26502/fjwhd.2644-28840062","DOIUrl":"https://doi.org/10.26502/fjwhd.2644-28840062","url":null,"abstract":"<p><strong>Background: </strong>Latin America has the highest regional average cesarean birth rates. One potential driver is cesarean birth by maternal request (CBMR).</p><p><strong>Methods: </strong>We analyzed of a large prospective cohort study of HIV-infected women in six Latin American countries.</p><p><strong>Results: </strong>Comparisons were made between women who chose CBMR (n = 38) and women with a medical indication for cesarean (n = 683). The only variable associated with CBMR was onset of labor (AOR 0.3 [0.1,0.9], p = 0.04).</p><p><strong>Conslusion: </strong>Spontaneous labor reduced the likelihood of a woman living with HIV to pursue CBMR in a large Latin American cohort.</p>","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"4 2","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"2021-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/c7/nihms-1715655.PMC8294197.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Squeeze and Freeze, A Periodic Consecutive Oocyte Retrieval Method for Poor Ovarian Responders, Increases The Chance of Childbearing 挤压和冷冻,一种针对卵巢反应不良的定期连续卵母细胞回收方法,增加了生育的机会
Pub Date : 2021-06-09 DOI: 10.21203/RS.3.RS-560941/V1
Yasutaka Murata, Fumika Oda, M. Shirai, Nanako Sato, A. Sugita, T. Murata
PurposeTo assess if consecutive oocyte retrieval (OR) of more than three times could be an effective method to obtain competent embryos becoming babies.MethodsTo maximize the chances of pregnancy for refractory infertile women, we designed a new treatment course, “Squeeze and freeze.” In this method, ovarian stimulation was initiated whenever the antral follicle was visible using ultrasound, regardless of the menstrual cycle stage for 3 months, aiming to retrieve all possible oocytes and collecting the maximum number of competent embryos for subsequent transfer. Eighty-eight patients underwent 101 treatment courses, in which retrievals at an average of 4.8 times were performed for 3 months. The clinical results and obstetric outcomes were retrospectively reviewed.ResultsThe ratio of matured oocytes, 2PN embryos, available embryos, fair blastocysts per oocyte, and number of available embryos or fair blastocysts per retrieval did not differ between the two initial and later attempts. Similarly, no significant differences were observed in these parameters between the follicular- and luteal-phase retrievals. After subsequent embryo transfer, 62 patients achieved clinical pregnancy, 49 had an ongoing pregnancy, 47 delivered healthy babies, and 8 conceived a second baby.ConclusionPeriodic consecutive OR is an efficient infertility treatment for refractory women. In this method, as many oocytes as possible are obtained from a patient in a limited period at the earliest stage of their life. More than three consecutive ORs, including luteal-phase ORs, could obtain competent embryos efficiently, increasing the chances of childbearing.
目的探讨连续三次以上的卵母细胞回收(OR)是否能有效获得适能胚胎成为婴儿。方法为使难治性不孕症患者的妊娠机会最大化,我们设计了一种新的治疗方案“挤压冷冻”。该方法在连续3个月的时间内,无论月经周期处于哪个阶段,只要超声能看到卵泡,就开始刺激卵巢,目的是回收所有可能的卵母细胞,收集最多数量的能态胚胎用于后续移植。88例患者共101个疗程,平均取药4.8次,疗程3个月。回顾性分析临床结果和产科结局。结果成熟卵母细胞、2PN胚胎、可得胚胎、每卵母细胞公平囊胚的比例以及每次可得胚胎或公平囊胚的数量在两次初始和后期尝试之间没有差异。同样,在卵泡期和黄体期的这些参数中也没有观察到显著差异。在随后的胚胎移植后,62例患者实现临床妊娠,49例持续妊娠,47例分娩健康婴儿,8例怀孕二胎。结论周期性连续手术是治疗难治性不孕症的有效方法。在这种方法中,在患者生命的最初阶段,在有限的时间内获得尽可能多的卵母细胞。连续3次以上,包括黄体期,可有效获得适能胚胎,增加了生育机会。
{"title":"Squeeze and Freeze, A Periodic Consecutive Oocyte Retrieval Method for Poor Ovarian Responders, Increases The Chance of Childbearing","authors":"Yasutaka Murata, Fumika Oda, M. Shirai, Nanako Sato, A. Sugita, T. Murata","doi":"10.21203/RS.3.RS-560941/V1","DOIUrl":"https://doi.org/10.21203/RS.3.RS-560941/V1","url":null,"abstract":"\u0000 Purpose\u0000\u0000To assess if consecutive oocyte retrieval (OR) of more than three times could be an effective method to obtain competent embryos becoming babies.\u0000Methods\u0000\u0000To maximize the chances of pregnancy for refractory infertile women, we designed a new treatment course, “Squeeze and freeze.” In this method, ovarian stimulation was initiated whenever the antral follicle was visible using ultrasound, regardless of the menstrual cycle stage for 3 months, aiming to retrieve all possible oocytes and collecting the maximum number of competent embryos for subsequent transfer. Eighty-eight patients underwent 101 treatment courses, in which retrievals at an average of 4.8 times were performed for 3 months. The clinical results and obstetric outcomes were retrospectively reviewed.\u0000Results\u0000\u0000The ratio of matured oocytes, 2PN embryos, available embryos, fair blastocysts per oocyte, and number of available embryos or fair blastocysts per retrieval did not differ between the two initial and later attempts. Similarly, no significant differences were observed in these parameters between the follicular- and luteal-phase retrievals. After subsequent embryo transfer, 62 patients achieved clinical pregnancy, 49 had an ongoing pregnancy, 47 delivered healthy babies, and 8 conceived a second baby.\u0000Conclusion\u0000\u0000Periodic consecutive OR is an efficient infertility treatment for refractory women. In this method, as many oocytes as possible are obtained from a patient in a limited period at the earliest stage of their life. More than three consecutive ORs, including luteal-phase ORs, could obtain competent embryos efficiently, increasing the chances of childbearing.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72829323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behavioral, Demographic, and Clinical determinants of HIV Status in Zambian Women 行为,人口统计和临床决定因素在赞比亚妇女艾滋病毒状况
Pub Date : 2021-05-08 DOI: 10.1101/2021.05.05.21256411
D. Gebreyohannes, J. Shen, K. Sams
The rate of human immunodeficiency virus (HIV) infection shows a diminishing trend globally while increasing in intensity of mortality, morbidity, and burden of HIV in Sub-Saharan Africa. The intertwined behavioral, demographic, and clinical determinants fueled the incidence of infections in Zambian women. This study aimed to determine the association between demographic, behavioral, and clinical determinants with HIV serostatus in Zambian women. With the conceptual framework of the World Health Organization Commission for Social Determinants of Health (CSDH) and the quantitative method of MANOVA, this study examined Zambian Demographic Health Survey data for Zambian women of two ages groups (adolescent and adult). The findings showed statistically significant results in the association between HIV serostatus and self-perceived HIV risk for both groups and in the association between education and HIV serostatus among women in both groups. However, there was no statistically significant association between behavioral, demographic, and clinical determinants of HIV serostatus. These findings imply the need to conduct prospective studies on such determinants to curb HIV and improve women community health in Africa. Keywords HIV serostatus; determinants of HIV serostatus, Self-perceived HIV risk, Zambia
人类免疫缺陷病毒(艾滋病毒)感染率在全球呈下降趋势,而在撒哈拉以南非洲,艾滋病毒的死亡率、发病率和负担都在增加。行为、人口统计和临床决定因素交织在一起,助长了赞比亚妇女感染的发生率。本研究旨在确定赞比亚妇女的人口统计学、行为和临床决定因素与HIV血清状态之间的关系。利用世界卫生组织健康问题社会决定因素委员会(CSDH)的概念框架和方差分析(MANOVA)的定量方法,本研究检查了赞比亚两个年龄组(青少年和成人)妇女的人口健康调查数据。研究结果显示,在两组中,艾滋病毒血清状态与自我感知的艾滋病毒风险之间的关联以及两组中妇女的教育程度与艾滋病毒血清状态之间的关联具有统计学意义。然而,行为、人口统计学和HIV血清状态的临床决定因素之间没有统计学上的显著关联。这些发现意味着需要对这些决定因素进行前瞻性研究,以遏制艾滋病毒并改善非洲妇女社区健康。HIV;血清状态;艾滋病毒血清状态的决定因素,自我感知的艾滋病毒风险,赞比亚
{"title":"Behavioral, Demographic, and Clinical determinants of HIV Status in Zambian Women","authors":"D. Gebreyohannes, J. Shen, K. Sams","doi":"10.1101/2021.05.05.21256411","DOIUrl":"https://doi.org/10.1101/2021.05.05.21256411","url":null,"abstract":"The rate of human immunodeficiency virus (HIV) infection shows a diminishing trend globally while increasing in intensity of mortality, morbidity, and burden of HIV in Sub-Saharan Africa. The intertwined behavioral, demographic, and clinical determinants fueled the incidence of infections in Zambian women. This study aimed to determine the association between demographic, behavioral, and clinical determinants with HIV serostatus in Zambian women. With the conceptual framework of the World Health Organization Commission for Social Determinants of Health (CSDH) and the quantitative method of MANOVA, this study examined Zambian Demographic Health Survey data for Zambian women of two ages groups (adolescent and adult). The findings showed statistically significant results in the association between HIV serostatus and self-perceived HIV risk for both groups and in the association between education and HIV serostatus among women in both groups. However, there was no statistically significant association between behavioral, demographic, and clinical determinants of HIV serostatus. These findings imply the need to conduct prospective studies on such determinants to curb HIV and improve women community health in Africa. Keywords HIV serostatus; determinants of HIV serostatus, Self-perceived HIV risk, Zambia","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"720 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86314277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revictimization and the Specificity Hypothesis- Do Different Subtypes of Interpersonal Violence Predict Each Other? 再受害与特异性假设——不同亚型的人际暴力是否相互预测?
Pub Date : 2021-03-10 DOI: 10.21203/RS.3.RS-296460/V1
L. Langer, F. Neuner
Background: Revictimization refers to the finding that victims of child abuse have an increased risk of experiencing violence as adolescents and adults. To date, revictimization has been well documented for sexual violence. Recent findings show that the same phenomenon occurs for physical and emotional types of violence and indicate specificity in the relationship. In particular, childhood sexual abuse predicts sexual violence in adulthood and childhood physical abuse predicts future physical victimization. Although emotional violence is among the most harmful types of maltreatment, emotional revictimization has not yet been systematically documented. The aim of this study was to investigate how the three different types of childhood abuse (sexual, physical, and emotional) were related to the three different types of adult victimization (sexual, physical, and emotional).Methods: In an online survey of 135 adult women with high levels of victimization, sexual, physical and emotional experiences of violence were assessed separately for childhood and adulthood.Results: Linear regressions indicated specific relationships between childhood sexual and physical abuse and sexual violence in adulthood (standardized beta coefficients .33*** and .21*), while childhood physical abuse predicts physical violence in adulthood (standardized beta coefficient .44***). Emotional violence experiences in adulthood were predicted by childhood sexual and emotional abuse (standardized beta coefficients .20*** and .08*).Conclusions: The findings partly support the specificity hypothesis of revictimization and have significant implications for practice, particularly for the development of more effective approaches to preventing repeated violence.
背景:再受害是指儿童虐待受害者在青少年和成人时期遭受暴力的风险增加。迄今为止,关于性暴力的再次受害情况已有充分的记录。最近的研究结果表明,同样的现象也发生在身体和情感类型的暴力中,并表明了这种关系的特殊性。特别是,儿童期的性虐待预示着成年期的性暴力,儿童期的身体虐待预示着未来的身体伤害。虽然情感暴力是最有害的虐待类型之一,但情感再受害尚未有系统的记录。本研究的目的是调查三种不同类型的儿童虐待(性、身体和情感)与三种不同类型的成人受害(性、身体和情感)之间的关系。方法:对135名受害程度较高的成年妇女进行在线调查,分别对儿童期和成年期的性暴力、身体暴力和情感暴力经历进行评估。结果:线性回归显示儿童期性虐待和身体虐待与成年期性暴力之间存在特定关系(标准化贝塔系数为0.33 ***和0.21 *),而儿童期身体虐待与成年期身体暴力之间存在特定关系(标准化贝塔系数为0.44 ***)。儿童期的性虐和情绪虐待可以预测成年期的情绪暴力经历(标准化贝塔系数分别为.20***和.08*)。结论:研究结果在一定程度上支持了再次受害的特异性假设,并对实践具有重要意义,特别是对制定更有效的预防重复暴力的方法具有重要意义。
{"title":"Revictimization and the Specificity Hypothesis- Do Different Subtypes of Interpersonal Violence Predict Each Other?","authors":"L. Langer, F. Neuner","doi":"10.21203/RS.3.RS-296460/V1","DOIUrl":"https://doi.org/10.21203/RS.3.RS-296460/V1","url":null,"abstract":"\u0000 Background: Revictimization refers to the finding that victims of child abuse have an increased risk of experiencing violence as adolescents and adults. To date, revictimization has been well documented for sexual violence. Recent findings show that the same phenomenon occurs for physical and emotional types of violence and indicate specificity in the relationship. In particular, childhood sexual abuse predicts sexual violence in adulthood and childhood physical abuse predicts future physical victimization. Although emotional violence is among the most harmful types of maltreatment, emotional revictimization has not yet been systematically documented. The aim of this study was to investigate how the three different types of childhood abuse (sexual, physical, and emotional) were related to the three different types of adult victimization (sexual, physical, and emotional).Methods: In an online survey of 135 adult women with high levels of victimization, sexual, physical and emotional experiences of violence were assessed separately for childhood and adulthood.Results: Linear regressions indicated specific relationships between childhood sexual and physical abuse and sexual violence in adulthood (standardized beta coefficients .33*** and .21*), while childhood physical abuse predicts physical violence in adulthood (standardized beta coefficient .44***). Emotional violence experiences in adulthood were predicted by childhood sexual and emotional abuse (standardized beta coefficients .20*** and .08*).Conclusions: The findings partly support the specificity hypothesis of revictimization and have significant implications for practice, particularly for the development of more effective approaches to preventing repeated violence.","PeriodicalId":74017,"journal":{"name":"Journal of women's health and development","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88294591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of women's health and development
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1