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Reply: The art of winning an unfair game: Immediate aortic repair for mesenteric malperfusion syndrome 回复:赢得不公平游戏的艺术:肠系膜灌注不良综合征的即刻主动脉修补术
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.013
James A. Brown MD, MS , Ibrahim Sultan MD
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引用次数: 0
POBS-Card, a new score of severe bleeding after cardiac surgery: Construction and external validation POBS-CARD:心脏手术后严重出血的新评分标准:构建与外部验证
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.008
Emmanuel Besnier MD, PhD , Pierre Schmidely MD , Guillaume Dubois MD , Prisca Lemonne MD , Lucie Todesco MD , Chadi Aludaat MD , Thierry Caus MD, PHD , Jean Selim MD, PhD , Emmanuel Lorne MD, PhD , Osama Abou-Arab MD, PhD

Objective

Bleeding after cardiac surgery leads to poor outcomes. The objective of the study was to build the PeriOperative Bleeding Score in Cardiac surgery (POBS-Card) to predict bleeding after cardiac surgery.

Methods

We conducted a retrospective cohort study in 2 academic hospitals (2016-2019). Inclusion criteria were adult patients after cardiac surgery under cardiopulmonary bypass. Exclusion criteria were heart transplantation, assistance, aortic dissection, and preoperative hemostasis diseases. Bleeding was defined by the universal definition for perioperative bleeding score ≥2. POBS-Card score was built using multivariate regression (derivation cohort, one center). The performance diagnosis was assessed using the area under the curve in a validation cohort (2 centers) and compared with other scores.

Results

In total, 1704 patients were included in the derivation cohort, 344 (20%) with bleeding. Preoperative factors were body mass index <25 kg/m2 (odds ratio [OR], 1.48 [1.14-1.93]), type of surgery (redo: OR, 1.76 [1.07-2.82]; combined: OR, 1.81 [1.19-2.74]; ascendant aorta: OR, 1.56 [1.02-2.38]), ongoing antiplatelet therapy (single: OR, 1.50 [1.09-2.05]; double: OR, 2.00 [1.15-3.37]), activated thromboplastin time ratio >1.2 (OR, 1.44 [1.03-1.99]), prothrombin ratio <60% (OR, 1.91 [1.21-2.97]), platelet count <150 g/L (OR, 1.74 [1.17-2.57]), and fibrinogen <3 g/L (OR, 1.33 [1.02-1.73]). In the validation cohort of 597 patients, the area under the curve was 0.645 [0.605-0.683] and was superior to other scores (WILL-BLEED, Papworth, TRUST, TRACK). A threshold >14 predicted bleeding with a sensitivity of 50% and a specificity of 73%.

Conclusions

POBS-Card score was superior to other scores in predicting severe bleeding after cardiac surgery. Performances remained modest, questioning the place of these scores in the perioperative strategy of bleeding-sparing.

目的心脏手术后出血会导致不良预后。该研究旨在建立心脏手术术前出血评分(POBS-Card),以预测心脏手术后的出血情况。方法我们在两家学术医院开展了一项回顾性队列研究(2016-2019 年)。纳入标准为在心肺旁路下进行心脏手术的成年患者。排除标准为心脏移植、辅助、主动脉夹层和术前止血疾病。出血按围手术期出血评分≥2的通用定义定义。POBS-Card 评分通过多元回归法得出(衍生队列,一个中心)。在验证队列(2 个中心)中使用曲线下面积评估了性能诊断,并与其他评分进行了比较。术前因素包括体重指数<25 kg/m2(几率比[OR],1.48 [1.14-1.93])、手术类型(重做:OR,1.76 [1.07-2.82];合并手术:OR,1.81 [1.19-2.74];升主动脉:OR,1.56 [1.02-2.38])、正在进行的抗血小板治疗(单次:OR,1.50 [1.09-2.05];双次:OR,2.00 [1.15-3.37])、活化凝血活酶时间比值>1.2(OR,1.44 [1.03-1.99])、凝血酶原比率<60%(OR,1.91 [1.21-2.97])、血小板计数<150 g/L(OR,1.74 [1.17-2.57])和纤维蛋白原<3 g/L(OR,1.33 [1.02-1.73])。在由 597 名患者组成的验证队列中,曲线下面积为 0.645 [0.605-0.683],优于其他评分(WILL-BLEED、Papworth、TRUST、TRACK)。结论POBS-Card 评分在预测心脏手术后严重出血方面优于其他评分。结论POBS-Card评分在预测心脏手术后严重出血方面优于其他评分,但其表现仍然一般,这对这些评分在围手术期预防出血策略中的地位提出了质疑。
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引用次数: 0
Current definitions of hemodynamic structural valve deterioration after bioprosthetic aortic valve replacement lack consistency 目前对生物人工主动脉瓣置换术后血流动力学结构性瓣膜恶化的定义缺乏一致性
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.02.023
Bart J.J. Velders MD , Michiel D. Vriesendorp MD, PhD , Federico M. Asch MD , Michael J. Reardon MD , Francois Dagenais MD , Michael G. Moront MD , Joseph F. Sabik III MD , Rolf H.H. Groenwold MD, PhD , Robert J.M. Klautz MD, PhD

Objective

New echocardiographic definitions have been proposed for hemodynamic structural valve deterioration. We aimed to study their consistency in classifying structural valve deterioration after surgical aortic valve replacement.

Methods

Data were used of patients undergoing surgical aortic valve replacement in a multicenter, prospective cohort study with a 5-year follow-up. All patients received the same stented bioprosthesis. Echocardiographic parameters were assessed by an independent core laboratory. Moderate or greater stenotic hemodynamic structural valve deterioration was defined according to Capodanno and colleagues, Dvir and colleagues, and the Valve Academic Research Consortium 3; regurgitation data were not considered in this analysis. Consistency was quantified on the basis of structural valve deterioration classification at subsequent time points.

Results

A total of 1118 patients received implants. Patients’ mean age was 70 years, and 75% were male. Hemodynamic structural valve deterioration at any visit was present in 51 patients (4.6%), 32 patients (2.9%), and 34 patients (3.0%) according to Capodanno, Dvir, and Valve Academic Research Consortium 3. A total of 1064 patients (95%) were never labeled with structural valve deterioration by any definition. After the first classification with structural valve deterioration, 59%, 59%, and 65% had no subsequent structural valve deterioration classification according to Capodanno, Dvir, and Valve Academic Research Consortium 3, respectively.

Conclusions

The current definitions of hemodynamic structural valve deterioration are strong negative predictors but inconsistent positive discriminators for the detection of stenotic hemodynamic structural valve deterioration. Although the diagnosis of structural valve deterioration may be categorical, echocardiographic indices lack this degree of precision in the first 5 years after surgical aortic valve replacement. The inconsistency of current structural valve deterioration definitions impedes the detection of true valve degeneration, which challenges the clinical usefulness of these definitions.

目的 对血流动力学结构性瓣膜恶化提出了新的超声心动图定义。我们的目的是研究这些定义在手术主动脉瓣置换术后结构性瓣膜恶化分类中的一致性。方法 在一项多中心、前瞻性队列研究中,对接受手术主动脉瓣置换术的患者进行了为期 5 年的随访。所有患者都接受了相同的支架生物假体。超声心动图参数由独立的核心实验室进行评估。根据Capodanno及其同事、Dvir及其同事和瓣膜学术研究联盟3对中度或更严重的狭窄血流动力学结构性瓣膜恶化进行了定义;本分析不考虑反流数据。根据后续时间点的结构性瓣膜恶化分类对一致性进行量化。患者的平均年龄为 70 岁,75% 为男性。根据 Capodanno、Dvir 和 Valve Academic Research Consortium 3 的分类,51 名患者(4.6%)、32 名患者(2.9%)和 34 名患者(3.0%)在任何一次就诊时均出现血流动力学结构性瓣膜恶化。共有 1064 名患者(95%)从未被任何定义标记为结构性瓣膜恶化。根据 Capodanno、Dvir 和瓣膜学术研究联盟 3,在首次进行结构性瓣膜恶化分类后,分别有 59%、59% 和 65% 的患者没有进行后续的结构性瓣膜恶化分类。虽然结构性瓣膜恶化的诊断可以分类,但在主动脉瓣置换术后的头 5 年中,超声心动图指标缺乏这种精确度。目前结构性瓣膜退化定义的不一致性阻碍了对真正瓣膜退化的检测,这对这些定义的临床实用性提出了挑战。
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引用次数: 0
Noncomplex ventricular arrhythmia associated with greater freedom from recurrent ectopy at 1 year after mitral repair surgery 二尖瓣修复手术后 1 年,非复杂性室性心律失常与较高的复发性异位自由度相关。
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.005
Dimosthenis Pandis MD, MSc , Navindra David BS , Ahmed EI-Eshmawi MD , Marc A. Miller MD , Percy Boateng MD , Ana Claudia Costa MD, PhD , Philip Robson PhD , Maria Giovanna Trivieri MD , Zahi Fayad PhD , Anelechi C. Anyanwu MD, MSc , David H. Adams MD

Objective

The effect of mitral valve (MV) surgery on the natural history of ventricular arrhythmia (VA) in patients with arrhythmic MV prolapse remains unknown. We sought to evaluate the cumulative incidence of VA at 1 year after surgical mitral repair.

Methods

A retrospective review of progressively captured data identified 204 consecutive patients who underwent elective MV repair for significant degenerative mitral regurgitation as a first-time cardiovascular intervention in a quaternary reference center between January 2018 and December 2020. A subset of 62 consecutive patients with diagnosed arrhythmic MV prolapse was further evaluated for recurrent VA after MV repair.

Results

The median age was 62 years (range, 27-77 years) and 26 of 62 (41.9%) were female. The median time from initial mitral regurgitation/MV prolaspe diagnosis-to-referral was 13.8 years (interquartile range [IQR], 5.4-25) and from VA diagnosis-to-referral was 8 years (IQR, 3-10.6). Using the Lown-Wolf classification, complex VA (Lown grade ≥3) was identified in 36 of 62 patients (58%) at baseline, whereas 8 of 62 (13%) had a cardioverter/defibrillator implanted for primary (4/8) or secondary (4/8) prevention. Left ventricular myocardial scar was confirmed in 23 of 34 (68%) of patients scanned at baseline. The prevailing valve phenotype was bileaflet Barlow (59/62; 95.2%). All patients underwent surgical MV repair by the same team. Surgical repair was stabilized with an annuloplasty prosthesis (median size 36 mm [IQR, 34-38]). Concomitant procedures included tricuspid valve repair (51/62; 82.3%), cryo-maze ± left atrial appendage exclusion (14/62, 23%), and endocardial cryoablation of VA ectopy (4/62; 6.5%). The 30-day and 1-year freedom from recurrent VA were 98.4% and 75.9%, respectively. Absent VA after mitral repair was uniformly observed in patients with minor VA at baseline. Absent VA after mitral repair was uniformly observed in patients with minor VA preoperatively. Complex baseline VA was the strongest predictor of recurrent VA (hazard ratio, 10.8; 95% confidence interval, 1.4-84.2; P = .024), irrespective of myocardial fibrosis.

Conclusions

In a series of 62 consecutive patients operated electively for arrhythmic mitral prolapse, VA remained undetected in 75.9% of patients at 1 year. Freedom from recurrent VA was greater among patients without complex VA preoperatively, whereas baseline Lown grade ≥3 was the strongest independent risk factor for recurrent VA at 1 year. These findings attest to the importance of early recognition and prompt referral of patients with mitral prolapse and progressive VA to specialty interdisciplinary care.

目的二尖瓣手术对心律失常性二尖瓣脱垂患者室性心律失常(VA)自然史的影响仍不清楚。我们试图评估二尖瓣手术修复后 1 年的室性心律失常累积发生率。方法回顾性审查逐步获取的数据,确定了 2018 年 1 月至 2020 年 12 月期间在一家四级参考中心首次接受心血管干预的 204 名连续患者,这些患者因显著退行性二尖瓣反流接受了选择性二尖瓣修复术。对62名确诊为心律失常二尖瓣脱垂的连续患者子集进行了进一步评估,以确定二尖瓣修复术后是否复发二尖瓣反流。从最初诊断二尖瓣反流/中上叶增生到转诊的中位时间为13.8年(四分位距[IQR],5.4-25),从诊断出VA到转诊的中位时间为8年(IQR,3-10.6)。根据 Lown-Wolf 分级法,62 名患者中有 36 人(58%)在基线时发现了复杂的 VA(Lown 分级≥3),62 人中有 8 人(13%)植入了心脏转复/除颤器,用于一级预防(4/8)或二级预防(4/8)。在基线扫描的 34 位患者中,有 23 位(68%)确认存在左心室心肌瘢痕。主要瓣膜表型为双叶巴洛瓣(59/62;95.2%)。所有患者都由同一个团队进行了中风瓣膜手术修复。手术修复时使用瓣环成形假体(中位尺寸为 36 毫米 [IQR,34-38])。同时进行的手术包括三尖瓣修复术(51/62;82.3%)、低温迷宫±左房阑尾切除术(14/62,23%)和VA异位的心内膜低温消融术(4/62;6.5%)。30天和1年内不再复发VA的比例分别为98.4%和75.9%。二尖瓣修复术后无VA的情况在基线时有轻微VA的患者中普遍存在。二尖瓣修复术后无VA的患者术前均有轻度VA。复杂基线VA是复发性VA的最强预测因素(危险比,10.8;95%置信区间,1.4-84.2;P = .024),与心肌纤维化无关。术前无复杂VA的患者更易复发VA,而基线Lown分级≥3是1年后复发VA的最强独立风险因素。这些研究结果证明了早期识别二尖瓣脱垂和进行性VA患者并及时转诊至专科跨学科治疗的重要性。
{"title":"Noncomplex ventricular arrhythmia associated with greater freedom from recurrent ectopy at 1 year after mitral repair surgery","authors":"Dimosthenis Pandis MD, MSc ,&nbsp;Navindra David BS ,&nbsp;Ahmed EI-Eshmawi MD ,&nbsp;Marc A. Miller MD ,&nbsp;Percy Boateng MD ,&nbsp;Ana Claudia Costa MD, PhD ,&nbsp;Philip Robson PhD ,&nbsp;Maria Giovanna Trivieri MD ,&nbsp;Zahi Fayad PhD ,&nbsp;Anelechi C. Anyanwu MD, MSc ,&nbsp;David H. Adams MD","doi":"10.1016/j.xjon.2024.04.005","DOIUrl":"10.1016/j.xjon.2024.04.005","url":null,"abstract":"<div><h3>Objective</h3><p>The effect of mitral valve (MV) surgery on the natural history of ventricular arrhythmia (VA) in patients with arrhythmic MV prolapse remains unknown. We sought to evaluate the cumulative incidence of VA at 1 year after surgical mitral repair.</p></div><div><h3>Methods</h3><p>A retrospective review of progressively captured data identified 204 consecutive patients who underwent elective MV repair for significant degenerative mitral regurgitation as a first-time cardiovascular intervention in a quaternary reference center between January 2018 and December 2020. A subset of 62 consecutive patients with diagnosed arrhythmic MV prolapse was further evaluated for recurrent VA after MV repair.</p></div><div><h3>Results</h3><p>The median age was 62 years (range, 27-77 years) and 26 of 62 (41.9%) were female. The median time from initial mitral regurgitation/MV prolaspe diagnosis-to-referral was 13.8 years (interquartile range [IQR], 5.4-25) and from VA diagnosis-to-referral was 8 years (IQR, 3-10.6). Using the Lown-Wolf classification, complex VA (Lown grade ≥3) was identified in 36 of 62 patients (58%) at baseline, whereas 8 of 62 (13%) had a cardioverter/defibrillator implanted for primary (4/8) or secondary (4/8) prevention. Left ventricular myocardial scar was confirmed in 23 of 34 (68%) of patients scanned at baseline. The prevailing valve phenotype was bileaflet Barlow (59/62; 95.2%). All patients underwent surgical MV repair by the same team. Surgical repair was stabilized with an annuloplasty prosthesis (median size 36 mm [IQR, 34-38]). Concomitant procedures included tricuspid valve repair (51/62; 82.3%), cryo-maze ± left atrial appendage exclusion (14/62, 23%), and endocardial cryoablation of VA ectopy (4/62; 6.5%). The 30-day and 1-year freedom from recurrent VA were 98.4% and 75.9%, respectively. Absent VA after mitral repair was uniformly observed in patients with minor VA at baseline. Absent VA after mitral repair was uniformly observed in patients with minor VA preoperatively. Complex baseline VA was the strongest predictor of recurrent VA (hazard ratio, 10.8; 95% confidence interval, 1.4-84.2; <em>P</em> = .024), irrespective of myocardial fibrosis.</p></div><div><h3>Conclusions</h3><p>In a series of 62 consecutive patients operated electively for arrhythmic mitral prolapse, VA remained undetected in 75.9% of patients at 1 year. Freedom from recurrent VA was greater among patients without complex VA preoperatively, whereas baseline Lown grade ≥3 was the strongest independent risk factor for recurrent VA at 1 year. These findings attest to the importance of early recognition and prompt referral of patients with mitral prolapse and progressive VA to specialty interdisciplinary care.</p></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Pages 94-113"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624001074/pdfft?md5=654dde242501a48612881a9d15e1694d&pid=1-s2.0-S2666273624001074-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-specific and organ-centric approach in malperfusion in acute type A dissection 急性 A 型夹层中灌注不良的患者特异性和器官中心方法
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.002
Bashisth Mishra Mch , Simiyu R. Namungu MMED , Abdifatah A. Mohamed MD
{"title":"Patient-specific and organ-centric approach in malperfusion in acute type A dissection","authors":"Bashisth Mishra Mch ,&nbsp;Simiyu R. Namungu MMED ,&nbsp;Abdifatah A. Mohamed MD","doi":"10.1016/j.xjon.2024.04.002","DOIUrl":"10.1016/j.xjon.2024.04.002","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Page 44"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624001049/pdfft?md5=57653fce47760fd7e905da7c0c7bb4a2&pid=1-s2.0-S2666273624001049-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140781329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of aortoesophageal fistula primarily using esophageal preservation 主要通过食管保留治疗主动脉食管瘘
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.004
Alexander Mills DO , Akiko Tanaka MD, PhD , Ashley Dawson MD , Robert Hetz MD , Holly Smith MD , Michael Lopez DO , Hazim Safi MD , Anthony Estrera MD

Objective

Aortoesophageal fistula is a rare, life-threatening condition. There is no consensus regarding the surgical management of the esophagus in this condition.

Methods

We retrospectively evaluated 13 patients diagnosed with aortoesophageal fistulas at a single institution from 2003 to 2021. Descriptive statistics were used to analyze patient characteristics, operative characteristics, and patient outcomes. Kaplan–Meier survival analysis was performed.

Results

Patients’ mean age was 63.5 years, and 6 (46.2%) were female. The most common presenting symptoms were hemoptysis/hematemesis (69.2%), chest/back pain (46.2%), and fever (38.5%). Twelve patients (92.3%) had a history of aortic procedures. The median time between the index operation and repair of the secondary aortoesophageal fistula in the 12 patients was 5 months. The index operation was a thoracic endovascular aortic repair in 10 of 12 patients (83.3%). Eleven patients (84.6%) underwent primary esophageal repair with flap coverage (omentum or muscle). One of these patients needed an esophagectomy within 1 year. The primary surgical management of the aorta was graft excision and replacement, aside from 1 patient who underwent primary repair. The 30-day survival was 69.2%, and 1-year and 5-year survivals were 31.7%. There were no recurrent infections at the esophageal fistula site.

Conclusions

Aortoesophageal fistula remains a rare condition, but its case numbers have increased with thoracic endovascular aortic repair. It continues to be a difficult condition to manage and has a high fatality rate. Esophageal-preserving surgery may be a safe and less-invasive option for patients with a small defect.

目的主动脉食管瘘是一种罕见的危及生命的疾病。方法我们回顾性评估了 2003 年至 2021 年在一家医疗机构确诊的 13 例主动脉食管瘘患者。我们使用描述性统计来分析患者特征、手术特征和患者预后。结果患者的平均年龄为 63.5 岁,其中 6 例(46.2%)为女性。最常见的首发症状是咯血/吐血(69.2%)、胸痛/背痛(46.2%)和发热(38.5%)。12名患者(92.3%)有主动脉手术史。这12名患者从接受手术到修复继发性主动脉食管瘘的中位时间为5个月。12名患者中有10名(83.3%)的手术是胸腔内主动脉血管修补术。11名患者(84.6%)接受了皮瓣覆盖(网膜或肌肉)的初级食管修复术。其中一名患者在 1 年内需要进行食管切除术。主动脉的主要手术治疗方法是移植物切除和置换,只有一名患者接受了初级修复术。30 天存活率为 69.2%,1 年和 5 年存活率为 31.7%。结论食管主动脉瘘仍然是一种罕见疾病,但随着胸腔内主动脉血管修复术的开展,其病例数有所增加。食管主动脉瘘仍然是一种难以治疗的疾病,而且死亡率很高。对于缺损较小的患者来说,保留食管的手术可能是一种安全、创伤较小的选择。
{"title":"Management of aortoesophageal fistula primarily using esophageal preservation","authors":"Alexander Mills DO ,&nbsp;Akiko Tanaka MD, PhD ,&nbsp;Ashley Dawson MD ,&nbsp;Robert Hetz MD ,&nbsp;Holly Smith MD ,&nbsp;Michael Lopez DO ,&nbsp;Hazim Safi MD ,&nbsp;Anthony Estrera MD","doi":"10.1016/j.xjon.2024.04.004","DOIUrl":"10.1016/j.xjon.2024.04.004","url":null,"abstract":"<div><h3>Objective</h3><p>Aortoesophageal fistula is a rare, life-threatening condition. There is no consensus regarding the surgical management of the esophagus in this condition.</p></div><div><h3>Methods</h3><p>We retrospectively evaluated 13 patients diagnosed with aortoesophageal fistulas at a single institution from 2003 to 2021. Descriptive statistics were used to analyze patient characteristics, operative characteristics, and patient outcomes. Kaplan–Meier survival analysis was performed.</p></div><div><h3>Results</h3><p>Patients’ mean age was 63.5 years, and 6 (46.2%) were female. The most common presenting symptoms were hemoptysis/hematemesis (69.2%), chest/back pain (46.2%), and fever (38.5%). Twelve patients (92.3%) had a history of aortic procedures. The median time between the index operation and repair of the secondary aortoesophageal fistula in the 12 patients was 5 months. The index operation was a thoracic endovascular aortic repair in 10 of 12 patients (83.3%). Eleven patients (84.6%) underwent primary esophageal repair with flap coverage (omentum or muscle). One of these patients needed an esophagectomy within 1 year. The primary surgical management of the aorta was graft excision and replacement, aside from 1 patient who underwent primary repair. The 30-day survival was 69.2%, and 1-year and 5-year survivals were 31.7%. There were no recurrent infections at the esophageal fistula site.</p></div><div><h3>Conclusions</h3><p>Aortoesophageal fistula remains a rare condition, but its case numbers have increased with thoracic endovascular aortic repair. It continues to be a difficult condition to manage and has a high fatality rate. Esophageal-preserving surgery may be a safe and less-invasive option for patients with a small defect.</p></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Pages 31-38"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624001062/pdfft?md5=3c0fe3be244cf9cb1470ed655f4e4cc7&pid=1-s2.0-S2666273624001062-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140785770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Costal margin reconstruction for slipping rib syndrome: Outcomes of more than 500 cases and advancements beyond earlier sutured repair technique 肋骨滑移综合征的肋缘重建术:500 多例病例的结果和早期缝合修复技术的进步
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.03.007
Adam J. Hansen MD, Jeremiah Hayanga MD, MPH, Alper Toker MD, Vinay Badhwar MD

Objectives

To evaluate results of sutured repair for slipping rib syndrome (SRS), identify failure points, and discuss technique modifications to improve outcomes through costal margin reconstruction (CMR).

Methods

Patients undergoing repair of SRS between February 2019 and February 2024 at an academic referral institution were retrospectively analyzed. Pain scores, quality of life, pain medication use, and reoperations were evaluated pre- and postoperatively at 1 and 6 months. In patients failing sutured repair we identified specific failure points and devised a new CMR technique to overcome them. Subsequent CMR patients were followed at 1, 6, 12, 18, and 24 months using the same outcome measures.

Results

Four hundred forty-nine patients underwent repair. Two hundred forty-one patients underwent sutured repair with revision required in 66. Median time to revision was 14 months. CMR was developed and performed in 247 patients. In CMR patients, preoperative mean pain score of 7.5 out of 10 dropped postoperatively to 4.0, 2.5, 1.9, 1.3, and 0.9 at 1, 6, 12, 18, and 24 months, respectively (P < .001). Mean quality of life of 38% improved to 73%, 83%, 88%, 93%, and 95% at the same intervals (P < .001). Preoperatively, 29% of patients chronically used opioid medications. Opioid use dropped postoperatively to 11%, 4%, 4%, 0%, and 0% at the same intervals. Use of nonopioid medications followed a similar pattern. One CMR patient required full revision.

Conclusions

SRS is a debilitating, but correctable disorder. Improved pain and quality of life, reduction in chronic opioid use, and freedom from revision surgery suggest that CMR should be considered the standard operation for SRS.

目的 评估肋骨滑脱综合征(SRS)缝合修复术的效果,确定失败点,并讨论通过肋缘重建(CMR)来改善疗效的技术改造方法。在术前和术后 1 个月和 6 个月对疼痛评分、生活质量、止痛药物使用和再次手术进行评估。在缝合修复失败的患者中,我们确定了特定的失败点,并设计了一种新的 CMR 技术来克服这些失败点。随后,我们在 1、6、12、18 和 24 个月对 CMR 患者进行了随访,并采用了相同的结果测量方法。241 名患者接受了缝合修复,其中 66 人需要进行翻修。中位修复时间为 14 个月。247名患者进行了CMR检查。在 CMR 患者中,术前平均疼痛评分为 7.5 分(满分 10 分),术后 1、6、12、18 和 24 个月分别降至 4.0、2.5、1.9、1.3 和 0.9 分(P < .001)。38%的患者的平均生活质量在相同的时间间隔内分别提高到73%、83%、88%、93%和95%(P < .001)。术前,29% 的患者长期使用阿片类药物。术后,阿片类药物的使用率分别降至 11%、4%、4%、0% 和 0%。非阿片类药物的使用情况与此类似。一名 CMR 患者需要进行全面翻修。疼痛和生活质量的改善、长期阿片类药物使用的减少以及免于翻修手术表明,CMR 应被视为 SRS 的标准手术。
{"title":"Costal margin reconstruction for slipping rib syndrome: Outcomes of more than 500 cases and advancements beyond earlier sutured repair technique","authors":"Adam J. Hansen MD,&nbsp;Jeremiah Hayanga MD, MPH,&nbsp;Alper Toker MD,&nbsp;Vinay Badhwar MD","doi":"10.1016/j.xjon.2024.03.007","DOIUrl":"https://doi.org/10.1016/j.xjon.2024.03.007","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate results of sutured repair for slipping rib syndrome (SRS), identify failure points, and discuss technique modifications to improve outcomes through costal margin reconstruction (CMR).</p></div><div><h3>Methods</h3><p>Patients undergoing repair of SRS between February 2019 and February 2024 at an academic referral institution were retrospectively analyzed. Pain scores, quality of life, pain medication use, and reoperations were evaluated pre- and postoperatively at 1 and 6 months. In patients failing sutured repair we identified specific failure points and devised a new CMR technique to overcome them. Subsequent CMR patients were followed at 1, 6, 12, 18, and 24 months using the same outcome measures.</p></div><div><h3>Results</h3><p>Four hundred forty-nine patients underwent repair. Two hundred forty-one patients underwent sutured repair with revision required in 66. Median time to revision was 14 months. CMR was developed and performed in 247 patients. In CMR patients, preoperative mean pain score of 7.5 out of 10 dropped postoperatively to 4.0, 2.5, 1.9, 1.3, and 0.9 at 1, 6, 12, 18, and 24 months, respectively (<em>P</em> &lt; .001). Mean quality of life of 38% improved to 73%, 83%, 88%, 93%, and 95% at the same intervals (<em>P</em> &lt; .001). Preoperatively, 29% of patients chronically used opioid medications. Opioid use dropped postoperatively to 11%, 4%, 4%, 0%, and 0% at the same intervals. Use of nonopioid medications followed a similar pattern. One CMR patient required full revision.</p></div><div><h3>Conclusions</h3><p>SRS is a debilitating, but correctable disorder. Improved pain and quality of life, reduction in chronic opioid use, and freedom from revision surgery suggest that CMR should be considered the standard operation for SRS.</p></div>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Pages 347-354"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624000664/pdfft?md5=53e4ab02a54de8967f7d2ec6c4ee0297&pid=1-s2.0-S2666273624000664-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141325241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Defining resectability: When do you try to take it out? 定义可拆除性:何时取出?
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.03.012
Harry Etienne MD, PhD , Bianca Battilana MM , Jonathan Spicer MD, PhD , Raphael S. Werner MD, MSc , Isabelle Opitz MD
{"title":"Defining resectability: When do you try to take it out?","authors":"Harry Etienne MD, PhD ,&nbsp;Bianca Battilana MM ,&nbsp;Jonathan Spicer MD, PhD ,&nbsp;Raphael S. Werner MD, MSc ,&nbsp;Isabelle Opitz MD","doi":"10.1016/j.xjon.2024.03.012","DOIUrl":"10.1016/j.xjon.2024.03.012","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Pages 338-346"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624000913/pdfft?md5=1af9d8abb787755f90ddb4f65dcd94d4&pid=1-s2.0-S2666273624000913-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenteric malperfusion syndrome is the game changer in acute aortic dissection 肠系膜灌注不良综合征是急性主动脉夹层的转折点
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.03.014
Koray Ak MD, PhD
{"title":"Mesenteric malperfusion syndrome is the game changer in acute aortic dissection","authors":"Koray Ak MD, PhD","doi":"10.1016/j.xjon.2024.03.014","DOIUrl":"10.1016/j.xjon.2024.03.014","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Page 41"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624000937/pdfft?md5=0e99e5b911d55c9fffad5b6a57c0b750&pid=1-s2.0-S2666273624000937-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discussion to: Outcomes of single- versus multi-port video-assisted thoracoscopic surgery: Data from a multicenter randomized controlled trial of video-assisted thoracoscopic surgery versus thoracotomy for lung cancer 讨论到:单孔与多孔视频辅助胸腔镜手术的疗效:视频辅助胸腔镜手术与开胸手术治疗肺癌的多中心随机对照试验数据
Pub Date : 2024-06-01 DOI: 10.1016/j.xjon.2024.04.011
{"title":"Discussion to: Outcomes of single- versus multi-port video-assisted thoracoscopic surgery: Data from a multicenter randomized controlled trial of video-assisted thoracoscopic surgery versus thoracotomy for lung cancer","authors":"","doi":"10.1016/j.xjon.2024.04.011","DOIUrl":"10.1016/j.xjon.2024.04.011","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"19 ","pages":"Pages 309-310"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666273624001141/pdfft?md5=e11649c1ea9361cb462ce1f1b2524926&pid=1-s2.0-S2666273624001141-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140786961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
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