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Commentator Discussion: Preliminary outcomes of quantitative flow ratio-guided coronary bypass grafting in primary valve surgery: A propensity score weighted analysis 评论员讨论:定量血流比引导冠状动脉旁路移植术在初级瓣膜手术中的初步结果:倾向得分加权分析
Pub Date : 2024-10-01 DOI: 10.1016/j.xjon.2024.07.007
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引用次数: 0
Prediction of functional coronary stenosis by computed tomography–derived fractional flow reserve in surgical revascularization 通过计算机断层扫描获得的分数血流储备预测外科血管重建术中的功能性冠状动脉狭窄情况
Pub Date : 2024-10-01 DOI: 10.1016/j.xjon.2024.07.012
Min-Seok Kim MD, PhD, MSc , Ah-Jin Ryu PhD , Jung Won Kim MD , Seong Wook Hwang MD , Ki-Bong Kim MD, PhD

Objectives

The aims of this study were (1) to compare computed tomography–derived fractional flow reserve (CT-FFR) values with graft patency and (2) to establish the cut-off value of CT-FFR for predicting competitive graft flow after coronary artery bypass grafting (CABG).

Methods

Of the 77 patients who underwent isolated CABG with an in situ internal thoracic artery (ITA)-based composite graft and who were also evaluated by preoperative cardiac CT, CT-FFR values were obtained in 74 patients. Early postoperative angiograms were performed in all 74 patients. Angiograms were performed to evaluate the grafts as well as the native coronary arteries to find any competitive flow present. Postoperative angiographic findings of graft flow were categorized as perfectly patent, bidirectionally competitive, unidirectionally competitive, and occluded. Receiver operating characteristic curve analysis of preoperative CT-FFR values for predicting postoperative angiographic competition was performed, and cutoff values of CT-FFR and area under the curve were identified.

Results

In total, 234 anastomoses were performed in 74 patients (median 3 [interquartile range, 2, 4] anastomoses per patient). Postoperative (median 1 [interquartile range, 1, 2] day) angiograms showed that 196 (83.8%) anastomoses were perfectly patent, 25 (10.7%) anastomoses were bidirectionally competitive, 12 (5.1%) anastomoses were unidirectionally competitive, and 1 (0.4%) anastomosis was occluded. Median CT-FFR values of the coronary arteries with perfectly patent, bidirectionally competitive, and unidirectionally competitive grafts were 0.658 (interquartile range, 0.500, 0.725), 0.809 (interquartile range, 0.789, 0.855), and 0.849 (interquartile range, 0.833, 0.865), respectively. The cutoff value of CT-FFR predicting competitive graft flow was 0.774 (sensitivity, 97.4%; specificity, 98.5% [area under the curve 0.977; P < .001]).

Conclusions

The diagnostic accuracy of CT-FFR for predicting competitive graft flow after CABG was high, and CT-FFR could be used as a guide for predicting functional coronary artery stenosis in surgical revascularization.
研究目的:(1) 比较计算机断层扫描得出的血流分数储备(CT-FFR)值与移植物通畅性;(2) 确定 CT-FFR 预测冠状动脉旁路移植术(CABG)后竞争性移植物血流的临界值。方法:在 77 位接受了以原位胸内动脉(ITA)为基础的复合移植物的分离式 CABG 的患者中,有 74 位患者在术前接受了心脏 CT 评估,并获得了 CT-FFR 值。对所有 74 名患者进行了术后早期血管造影。血管造影的目的是评估移植物和原生冠状动脉,以发现是否存在竞争性血流。术后血管造影发现的移植物血流分为完全通畅、双向竞争性、单向竞争性和闭塞。对预测术后血管造影竞争的术前 CT-FFR 值进行了接收者操作特征曲线分析,并确定了 CT-FFR 的临界值和曲线下面积。术后(中位 1 [四分位间范围,1,2]天)血管造影显示,196(83.8%)个吻合口完全通畅,25(10.7%)个吻合口为双向竞争性吻合口,12(5.1%)个吻合口为单向竞争性吻合口,1(0.4%)个吻合口闭塞。完全通畅、双向竞争性和单向竞争性移植物冠状动脉的 CT-FFR 中位值分别为 0.658(四分位数间距,0.500,0.725)、0.809(四分位数间距,0.789,0.855)和 0.849(四分位数间距,0.833,0.865)。CT-FFR预测竞争性移植物血流的临界值为0.774(敏感性97.4%;特异性98.5% [曲线下面积0.977;P< .001])。
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引用次数: 0
Commentator Discussion: Predicting operative mortality in patients who undergo elective, open thoracoabdominal aortic aneurysm repair. 评论员讨论:预测择期胸腹主动脉瘤开腹修补术患者的手术死亡率。
Pub Date : 2024-09-28 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.024
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引用次数: 0
Healthcare economic burden of unresolved slipping rib syndrome. 未解决的滑肋综合征的医疗经济负担。
Pub Date : 2024-09-26 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.022
Adam J Hansen, J W Awori Hayanga, Alper Toker, Vinay Badhwar

Objective: To evaluate the healthcare costs associated with unresolved slipping rib syndrome (SRS).

Methods: Data pertaining to patients who underwent operative repair for SRS at our academic institution were analyzed retrospectively. Duration of symptoms, previous management efforts, number of healthcare provider consultations, imaging studies, adjunctive surgical and pain management procedures performed to treat the symptoms, and prior unsuccessful SRS operations were catalogued. US Medicare billing standards were used to average costs for provider visits and overall cost of surgical and interventional pain management procedures. Analgesic medication costs were determined using generic pricing.

Results: Between February 2019 and January 2024, a total of 435 consecutive patients spent a median of 36 months searching for a diagnosis and symptom relief prior to evaluation at our institution. The median number of physicians consulted was 6 (range, 0-75). The total cost of physician visits was $2,990,434 USD. The median number of imaging studies was 5 (range, 0-55), at a total cost of $965,949. Cholecystectomy was performed in 47 patients (11%), at a cost of $716,750. Previous SRS surgery had been attempted 150 times at various institutions and accounted for $4,500,000 (estimated $30,000 per operation in billing). Intercostal nerve block, ablation, and spinal cord stimulator placement had been performed in 30%, 15%, and 5% of the patients, respectively, at a total cost of $963,821. The median number of analgesic medications used per patient was 1 (mean, 1.3; range, 0-5); the total medication cost was $1,111,860. The total preoperative healthcare cost in our series was $12,445,173, for an average of $28,610 per patient.

Conclusions: SRS remains poorly understood. Symptoms can be severe and debilitating, and patients frequently consume significant healthcare resources. With recognition and definitive surgical management, SRS may be addressed successfully. Prompt treatment has the potential for significant healthcare savings.

目的:评估未解决的滑肋综合征(SRS)的医疗费用。方法:回顾性分析我院接受SRS手术修复的患者资料。对症状持续时间、以前的管理努力、医疗保健提供者咨询次数、影像学检查、为治疗症状而进行的辅助手术和疼痛管理程序以及以前不成功的SRS手术进行了分类。使用美国医疗保险计费标准来平均就诊费用和手术和介入性疼痛管理程序的总费用。镇痛药物费用采用仿制药定价。结果:在2019年2月至2024年1月期间,共有435名连续患者在我们机构评估之前花费了中位数为36个月的时间来寻找诊断和症状缓解。咨询医生的中位数为6(范围0-75)。医生就诊的总费用为2990434美元。影像学检查的中位数为5次(范围0-55次),总费用为965,949美元。47例患者(11%)接受了胆囊切除术,费用为716,750美元。以前的SRS手术在不同的机构进行了150次,费用为450万美元(估计每次手术费用为3万美元)。肋间神经阻滞、消融和脊髓刺激器放置分别在30%、15%和5%的患者中进行,总费用为963,821美元。每位患者使用的镇痛药物中位数为1种(平均为1.3种;范围0 - 5);总药费为1,111,860美元。在我们的研究中,术前医疗保健总费用为12,445,173美元,平均每位患者为28,610美元。结论:对SRS的了解仍然很少。症状可能很严重,使人虚弱,患者经常消耗大量的医疗资源。有了认识和明确的外科治疗,SRS可能会成功解决。及时治疗有可能节省大量医疗费用。
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引用次数: 0
Intraoperative right ventricular end-systolic pressure-volume loop analysis in patients undergoing cardiac surgery: A proof-of-concept methodology. 心脏手术患者术中右心室收缩末期压力-容量环分析:概念验证方法学。
Pub Date : 2024-09-26 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.020
Vahid Kiarad, Feroze Mahmood, Mona Hedayat, Rayaan Yunus, Alina Nicoara, David Liu, Louis Chu, Vankatachalam Senthilnathan, Masashi Kai, Kamal Khabbaz

Background: Perioperative right ventricular (RV) dysfunction is associated with increased morbidity and mortality in cardiac surgery patients. This study aimed to demonstrate proof of concept in generating intraoperative RV pressure-volume (PV) loops and conducting an end-systolic PV relationship (ESPVR) analysis using data obtained from routinely used intraoperative monitors.

Methods: Adult patients undergoing cardiac surgery with the placement of a pulmonary artery catheter (PAC) between May 2023 and March 2024 were included prospectively. The PV loops were generated using 3-dimensional echocardiographic RV volume data and continuous RV pressure data obtained from a PAC. The volume-time and pressure-time curves were digitized using the semiautomatic WebPlotDigitizer program and synchronized to reconstruct an RV PV loop and analyze ESPVR using the previously validated single-beat method.

Results: Intraoperative RV PV loops were generated for 25 patients, including 17 patients with preserved RV systolic function (group 1) and 8 patients with reduced systolic function (group 2). Mean Ees, Ea, and Ees/Ea ratio were 0.63 ± 0.25 mm Hg/mL, 0.60 ± 0.23 mm Hg/mL, and 1.0 8 ± 0.31 mm Hg/mL, respectively, by the Pmax method and 0.56 ± 0.32 mm Hg/mL, 0.60 ± 0.23 mm Hg/mL, and 0.91 ± 0.21 mm Hg/mL, respectively, by the V0 method. Group 1 had a significantly higher Ees compared to group 2 regardless of the calculation method and a larger Ees/Ea ratio calculated by the V0 method.

Conclusions: It is clinically feasible to derive RV PV loops from routine hemodynamic and echocardiographic data. With further validation and technological support, this can be a potential real-time intraoperative RV function monitoring tool.

背景:围手术期右心室功能障碍与心脏手术患者发病率和死亡率增加有关。本研究旨在验证术中心室压力-容积(PV)循环产生的概念,并利用术中常规使用的监护仪获得的数据进行收缩期末期PV关系(ESPVR)分析。方法:前瞻性纳入2023年5月至2024年3月期间接受心脏手术并放置肺动脉导管(PAC)的成年患者。利用三维超声心动图右心室容积数据和PAC获得的连续右心室压力数据生成PV环路。使用半自动WebPlotDigitizer程序对容积时间和压力时间曲线进行数字化,并同步重建右心室PV环路,并使用先前验证的单拍方法分析ESPVR。结果:术中房车PV循环生成25例,其中17患者保存房车收缩功能(组1)收缩功能下降患者和8(组2)。意思是ee, Ea和ee / Ea比率分别为0.63±0.25 mm Hg / mL, 0.60±0.23 mm Hg /毫升,8和1.0±0.31毫米汞柱/ mL,分别由Pmax方法和0.56±0.32 mm Hg /毫升,0.60±0.23 mm Hg /毫升,和0.91±0.21毫米汞柱/ mL,分别由V0方法。无论采用何种计算方法,1组的Ees均显著高于2组,且采用V0法计算的Ees/Ea比值较大。结论:从常规血流动力学和超声心动图数据推断右室PV袢在临床上是可行的。在进一步的验证和技术支持下,这可能成为一种潜在的术中心室功能实时监测工具。
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引用次数: 0
Commentator Discussion: Pediatric cardiac surgical site infections: A single center quality improvement initiative. 讲解员讨论:儿童心脏手术部位感染:单中心质量改进倡议。
Pub Date : 2024-09-24 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.017
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引用次数: 0
Three-dimensional morphometry of the human thoracic aorta using centerline analysis based on least-squares plane fitting. 基于最小二乘平面拟合中心线分析的人胸主动脉三维形态测量。
Pub Date : 2024-09-24 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.016
Hiroshi Nagamine, Kenji Kishita, Yuta Tsukada, Hiroshi Nagano, Mitsuru Asano

Objective: A novel approach to 3-dimensional morphometry of the thoracic aorta was developed by applying centerline analysis based on least-squares plane fitting, and a preliminary study was conducted using computed tomography imaging data.

Methods: We retrospectively compared 3 groups of patients (16 controls without aortic disease, and 16 cases each with acute type B aortic dissection and congenital bicuspid aortic valve). In addition to the standard assessment indices for curvature κ and torsion τ, we conducted coordinate transformation based on the least-squares plane, divided the centerline into 3 representative features (transverse, anterior-posterior, and longitudinal displacements), and analyzed the overall and local displacement in each direction. The transverse displacement, represented by the distance of the centerline from the least-squares plane, was curve-fitted to the damped oscillation waveform. Thereafter, damped oscillation parameters were compared for each group.

Results: Curvature κ exhibited a bimodal distribution, with peaks observed in the ascending aorta and aortic arch, and torsion τ exhibited a transition from positive to negative values in the arch. There were significant differences in the mean displacement between the groups for each direction (transverse P = .0083, anteroposterior P = .010, longitudinal P = 1.32 × 10-6). Furthermore, interval integral analysis revealed that several intervals exhibited significant differences between groups in each direction. The amplitude of damped oscillation parameters was significantly larger in the bicuspid aortic valve group than in the control and type B aortic dissection groups.

Conclusions: The novel analytical approach permitted a quantitative assessment of the 3-dimensional morphological differences between the control, type B aortic dissection, and bicuspid aortic valve groups.

目的:应用基于最小二乘平面拟合的中心线分析方法,建立胸主动脉三维形态测量新方法,并利用计算机断层成像数据进行初步研究。方法:回顾性比较3组患者(无主动脉疾病的对照组16例,急性B型主动脉夹层合并先天性双尖瓣主动脉瓣各16例)。除了曲率κ和扭转τ的标准评价指标外,我们基于最小二乘平面进行坐标变换,将中心线划分为3个代表性特征(横向、前后和纵向位移),并在每个方向上分析整体和局部位移。以中心线到最小二乘平面的距离表示的横向位移曲线拟合到阻尼振荡波形。然后比较各组的阻尼振荡参数。结果:曲率κ呈双峰分布,在升主动脉和主动脉弓处出现峰值,而扭转τ在主动脉弓处呈现由正向负的转变。各组间各方向平均移位量差异有统计学意义(横向P = 0.0083,正向P = 0.010,纵向P = 1.32 × 10-6)。此外,区间积分分析显示,多个区间在各方向上表现出组间显著差异。二尖瓣主动脉瓣组的阻尼振荡参数幅值明显大于对照组和B型主动脉夹层组。结论:新的分析方法可以定量评估对照组、B型主动脉夹层组和二尖瓣主动脉瓣组之间的三维形态学差异。
{"title":"Three-dimensional morphometry of the human thoracic aorta using centerline analysis based on least-squares plane fitting.","authors":"Hiroshi Nagamine, Kenji Kishita, Yuta Tsukada, Hiroshi Nagano, Mitsuru Asano","doi":"10.1016/j.xjon.2024.09.016","DOIUrl":"https://doi.org/10.1016/j.xjon.2024.09.016","url":null,"abstract":"<p><strong>Objective: </strong>A novel approach to 3-dimensional morphometry of the thoracic aorta was developed by applying centerline analysis based on least-squares plane fitting, and a preliminary study was conducted using computed tomography imaging data.</p><p><strong>Methods: </strong>We retrospectively compared 3 groups of patients (16 controls without aortic disease, and 16 cases each with acute type B aortic dissection and congenital bicuspid aortic valve). In addition to the standard assessment indices for curvature κ and torsion τ, we conducted coordinate transformation based on the least-squares plane, divided the centerline into 3 representative features (transverse, anterior-posterior, and longitudinal displacements), and analyzed the overall and local displacement in each direction. The transverse displacement, represented by the distance of the centerline from the least-squares plane, was curve-fitted to the damped oscillation waveform. Thereafter, damped oscillation parameters were compared for each group.</p><p><strong>Results: </strong>Curvature κ exhibited a bimodal distribution, with peaks observed in the ascending aorta and aortic arch, and torsion τ exhibited a transition from positive to negative values in the arch. There were significant differences in the mean displacement between the groups for each direction (transverse <i>P</i> = .0083, anteroposterior <i>P</i> = .010, longitudinal <i>P</i> = 1.32 × 10<sup>-6</sup>). Furthermore, interval integral analysis revealed that several intervals exhibited significant differences between groups in each direction. The amplitude of damped oscillation parameters was significantly larger in the bicuspid aortic valve group than in the control and type B aortic dissection groups.</p><p><strong>Conclusions: </strong>The novel analytical approach permitted a quantitative assessment of the 3-dimensional morphological differences between the control, type B aortic dissection, and bicuspid aortic valve groups.</p>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"22 ","pages":"144-155"},"PeriodicalIF":0.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated line-clearing chest tubes reduce postoperative pain and atrial fibrillation after cardiac surgery. 自动清线胸管减少心脏手术后的疼痛和房颤。
Pub Date : 2024-09-24 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.019
Elbert E Heng, Oluwatomisin Obafemi, Danielle Mullis, Alyssa Garrison, Hanjay Wang, Jack H Boyd

Objective: Recent advancements in chest tube technologies have gained interest for their ability to enhance postoperative recovery via reduction of retained blood syndrome after cardiothoracic surgery. The present study investigates the effect of the Centese Thoraguard automated line-clearance chest tube system on postoperative pain and recovery after cardiac surgery.

Methods: This was a single-center retrospective review of 1771 adult patients undergoing nonemergency cardiac surgery between January 2021 and December 2022. Perioperative data were analyzed in 184 patients undergoing surgery with Thoraguard automated clearance chest tubes and 1587 patients with conventional chest tubes. Postoperative outcomes were compared in a propensity-matched cohort of 133 patient pairs with similar preoperative characteristics.

Results: Patients undergoing cardiac surgery with automated clearance chest tubes demonstrated significant reductions in pain scores (0-10) compared with conventional chest tubes on the third postoperative day (5 vs 6, P = .02) and at hospital discharge (0 vs 3, P = .04). Automated clearance chest tubes were associated with a shorter time on the ventilator (5.3 vs 5.8 hours, P < .001). There was a significant reduction in postoperative atrial fibrillation (18.1% vs 30.8%, P = .02) in patients receiving automated clearance chest tubes. There were no significant differences in mortality, myocardial infarction, or stroke between automated line-clearing and conventional chest tubes.

Conclusions: The use of the Thoraguard automated line-clearing chest tube system in routine cardiac surgery was associated with improved postoperative pain control, decreased ventilator duration, and decreased postoperative atrial fibrillation without increased morbidity or mortality.

目的:胸管技术的最新进展引起了人们的兴趣,因为它们能够通过减少心胸外科手术后潴留血综合征来增强术后恢复。本研究探讨了Centese Thoraguard自动清线胸管系统对心脏手术后疼痛和恢复的影响。方法:这是一项单中心回顾性研究,纳入了2021年1月至2022年12月期间接受非紧急心脏手术的1771名成年患者。我们分析了184例采用Thoraguard自动清除胸管和1587例常规胸管的围手术期数据。在133对具有相似术前特征的患者的倾向匹配队列中比较术后结果。结果:与常规胸管相比,采用自动清除胸管的心脏手术患者在术后第三天(5比6,P = 0.02)和出院时(0比3,P = 0.04)疼痛评分(0-10)显著降低。在接受自动清除胸管的患者中,自动清除胸管与更短的呼吸机使用时间相关(5.3小时vs 5.8小时,P P = 0.02)。在死亡率、心肌梗死或卒中方面,自动清线和常规胸管没有显著差异。结论:在常规心脏手术中使用Thoraguard自动清线胸管系统可改善术后疼痛控制,缩短呼吸机使用时间,减少术后心房颤动,而不增加发病率或死亡率。
{"title":"Automated line-clearing chest tubes reduce postoperative pain and atrial fibrillation after cardiac surgery.","authors":"Elbert E Heng, Oluwatomisin Obafemi, Danielle Mullis, Alyssa Garrison, Hanjay Wang, Jack H Boyd","doi":"10.1016/j.xjon.2024.09.019","DOIUrl":"https://doi.org/10.1016/j.xjon.2024.09.019","url":null,"abstract":"<p><strong>Objective: </strong>Recent advancements in chest tube technologies have gained interest for their ability to enhance postoperative recovery via reduction of retained blood syndrome after cardiothoracic surgery. The present study investigates the effect of the Centese Thoraguard automated line-clearance chest tube system on postoperative pain and recovery after cardiac surgery.</p><p><strong>Methods: </strong>This was a single-center retrospective review of 1771 adult patients undergoing nonemergency cardiac surgery between January 2021 and December 2022. Perioperative data were analyzed in 184 patients undergoing surgery with Thoraguard automated clearance chest tubes and 1587 patients with conventional chest tubes. Postoperative outcomes were compared in a propensity-matched cohort of 133 patient pairs with similar preoperative characteristics.</p><p><strong>Results: </strong>Patients undergoing cardiac surgery with automated clearance chest tubes demonstrated significant reductions in pain scores (0-10) compared with conventional chest tubes on the third postoperative day (5 vs 6, <i>P</i> = .02) and at hospital discharge (0 vs 3, <i>P</i> = .04). Automated clearance chest tubes were associated with a shorter time on the ventilator (5.3 vs 5.8 hours, <i>P</i> < .001). There was a significant reduction in postoperative atrial fibrillation (18.1% vs 30.8%, <i>P</i> = .02) in patients receiving automated clearance chest tubes. There were no significant differences in mortality, myocardial infarction, or stroke between automated line-clearing and conventional chest tubes.</p><p><strong>Conclusions: </strong>The use of the Thoraguard automated line-clearing chest tube system in routine cardiac surgery was associated with improved postoperative pain control, decreased ventilator duration, and decreased postoperative atrial fibrillation without increased morbidity or mortality.</p>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"22 ","pages":"85-94"},"PeriodicalIF":0.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentator Discussion: Fifteen years' experience of direct bridge with venoarterial extracorporeal membrane oxygenation to heart transplantation. 解说员讨论:15年静脉外膜氧合直接桥接心脏移植经验。
Pub Date : 2024-09-24 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.018
{"title":"Commentator Discussion: Fifteen years' experience of direct bridge with venoarterial extracorporeal membrane oxygenation to heart transplantation.","authors":"","doi":"10.1016/j.xjon.2024.09.018","DOIUrl":"https://doi.org/10.1016/j.xjon.2024.09.018","url":null,"abstract":"","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"22 ","pages":"304-305"},"PeriodicalIF":0.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative cardiac arrest in patients undergoing congenital cardiac surgery. 先天性心脏手术患者的术中心脏骤停。
Pub Date : 2024-09-23 eCollection Date: 2024-12-01 DOI: 10.1016/j.xjon.2024.09.015
Morgan L Brown, Steven J Staffa, Phillip S Adams, Lisa A Caplan, Stephen J Gleich, Jennifer L Hernandez, Martina Richtsfeld, Lori Q Riegger, David F Vener

Objective: To describe intraoperative cardiac arrest in patients undergoing congenital heart surgery.

Methods: The Society of Thoracic Surgeons Congenital Heart Surgery Database was queried. Predictors of intraoperative cardiac arrest were assessed using univariate and multivariable analyses. The univariate relationship between intraoperative cardiac arrest was also compared with available outcomes in the database.

Results: A total of 92,764 cases had anesthesia adverse event data, and 357 patients (0.38%) had an intraoperative cardiac arrest. Multivariable predictors of an intraoperative cardiac arrest included age (odds ratio [OR], 0.98 per year; 95% confidence interval [CI], 0.97-0.99; P = .036), preoperative cardiac arrest (<48 hours) (OR, 9.6; 95% CI 6.3-14.6, P < .001), preoperative neurologic deficit (OR, 2.0; 95% CI, 1.3-3.1, P = .002), noninsulin-dependent diabetes mellitus (OR, 6.4; 95% CI, 1.9-21.9, P = .003), increasing Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery (STAT) category (OR, 2.3 for STAT 5 vs STAT 1; 95% CI, 1.3-3.9, P = .003), urgent (OR, 2.0; 95% CI, 1.6-2.6, P < .001) or emergent surgery (OR, 3.1; 95% CI, 1.9-5.0, P < .001), and increasing length of total operating room time (OR, 1.2 per hour; 95% CI, 1.2-1.3, P < .001). Intraoperative cardiac arrest was associated with a greater 30-day mortality (14.6% vs 1.8%, P < .001). There were more morbidities in the intraoperative cardiac arrest group including postoperative neurologic deficits (12% vs 1.0%, P < .001), multisystem organ failure (5.9% vs 0.7%, P < .001), and greater rates of unplanned reoperation (19.3% vs 5.0%, P < .001) or interventional cardiac catheterization (7% vs 3.2%, P < .001).

Conclusions: The incidence of intraoperative cardiac arrest is low; however, it is an important indicator of significant patient perioperative morbidity and mortality.

目的:描述先天性心脏手术患者术中心脏骤停的情况。方法:查询美国胸外科学会先天性心脏外科数据库。采用单变量和多变量分析评估术中心脏骤停的预测因素。术中心脏骤停的单变量关系也与数据库中可用的结果进行了比较。结果:共有92764例患者出现麻醉不良事件,357例(0.38%)患者出现术中心脏骤停。术中心脏骤停的多变量预测因素包括年龄(优势比[OR], 0.98 /年;95%置信区间[CI], 0.97-0.99;P = 0.036),术前心脏骤停(P = 0.002),非胰岛素依赖型糖尿病(OR, 6.4;95% CI, 1.9-21.9, P = 0.003),增加胸外科学会-欧洲心胸外科协会(STAT)分类(OR, STAT 5 vs STAT 1;95% CI, 1.3-3.9, P = 0.003),紧急(OR, 2.0;95% CI, 1.6-2.6, P P P P P P P P P结论:术中心脏骤停发生率低;然而,它是患者围手术期发病率和死亡率的重要指标。
{"title":"Intraoperative cardiac arrest in patients undergoing congenital cardiac surgery.","authors":"Morgan L Brown, Steven J Staffa, Phillip S Adams, Lisa A Caplan, Stephen J Gleich, Jennifer L Hernandez, Martina Richtsfeld, Lori Q Riegger, David F Vener","doi":"10.1016/j.xjon.2024.09.015","DOIUrl":"https://doi.org/10.1016/j.xjon.2024.09.015","url":null,"abstract":"<p><strong>Objective: </strong>To describe intraoperative cardiac arrest in patients undergoing congenital heart surgery.</p><p><strong>Methods: </strong>The Society of Thoracic Surgeons Congenital Heart Surgery Database was queried. Predictors of intraoperative cardiac arrest were assessed using univariate and multivariable analyses. The univariate relationship between intraoperative cardiac arrest was also compared with available outcomes in the database.</p><p><strong>Results: </strong>A total of 92,764 cases had anesthesia adverse event data, and 357 patients (0.38%) had an intraoperative cardiac arrest. Multivariable predictors of an intraoperative cardiac arrest included age (odds ratio [OR], 0.98 per year; 95% confidence interval [CI], 0.97-0.99; <i>P</i> = .036), preoperative cardiac arrest (<48 hours) (OR, 9.6; 95% CI 6.3-14.6, <i>P</i> < .001), preoperative neurologic deficit (OR, 2.0; 95% CI, 1.3-3.1, <i>P</i> = .002), noninsulin-dependent diabetes mellitus (OR, 6.4; 95% CI, 1.9-21.9, <i>P</i> = .003), increasing Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery (STAT) category (OR, 2.3 for STAT 5 vs STAT 1; 95% CI, 1.3-3.9, <i>P</i> = .003), urgent (OR, 2.0; 95% CI, 1.6-2.6, <i>P</i> < .001) or emergent surgery (OR, 3.1; 95% CI, 1.9-5.0, <i>P</i> < .001), and increasing length of total operating room time (OR, 1.2 per hour; 95% CI, 1.2-1.3, <i>P</i> < .001). Intraoperative cardiac arrest was associated with a greater 30-day mortality (14.6% vs 1.8%, <i>P</i> < .001). There were more morbidities in the intraoperative cardiac arrest group including postoperative neurologic deficits (12% vs 1.0%, <i>P</i> < .001), multisystem organ failure (5.9% vs 0.7%, <i>P</i> < .001), and greater rates of unplanned reoperation (19.3% vs 5.0%, <i>P</i> < .001) or interventional cardiac catheterization (7% vs 3.2%, <i>P</i> < .001).</p><p><strong>Conclusions: </strong>The incidence of intraoperative cardiac arrest is low; however, it is an important indicator of significant patient perioperative morbidity and mortality.</p>","PeriodicalId":74032,"journal":{"name":"JTCVS open","volume":"22 ","pages":"427-437"},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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