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A Deep Learning-Driven Autonomous System for Retinal Vein Cannulation: Validation Using a Chicken Embryo Model. 一种深度学习驱动的自主视网膜静脉插管系统:利用鸡胚胎模型进行验证。
Yi Wang, Peiyao Zhang, Mojtaba Esfandiari, Peter Gehlbach, Iulian I Iordachita

Retinal vein cannulation (RVC) is a minimally invasive microsurgical procedure for treating retinal vein occlusion (RVO), a leading cause of vision impairment. However, the small size and fragility of retinal veins, coupled with the need for high-precision, tremor-free needle manipulation, create significant technical challenges. These limitations highlight the need for robotic assistance to improve accuracy and stability. This study presents an automated robotic system with a top-down microscope and B-scan optical coherence tomography (OCT) imaging for precise depth sensing. Deep learning-based models enable real-time needle navigation, contact detection, and vein puncture recognition, using a chicken embryo model as a surrogate for human retinal veins. The system autonomously detects needle position and puncture events with 85% accuracy. The experiments demonstrate notable reductions in navigation and puncture times compared to manual methods. Our results demonstrate the potential of integrating advanced imaging and deep learning to automate microsurgical tasks, providing a pathway for safer and more reliable RVC procedures with enhanced precision and reproducibility.

视网膜静脉插管(RVC)是一种微创显微外科手术治疗视网膜静脉闭塞(RVO),一个主要原因的视力损害。然而,视网膜静脉的小尺寸和脆弱性,加上对高精度、无抖动的针头操作的需求,带来了重大的技术挑战。这些限制突出了机器人辅助提高精度和稳定性的必要性。本研究提出了一种自动化机器人系统,该系统具有自上而下的显微镜和b扫描光学相干断层扫描(OCT)成像,用于精确的深度传感。基于深度学习的模型使用鸡胚胎模型作为人类视网膜静脉的替代品,实现了实时针头导航、接触检测和静脉穿刺识别。该系统自动检测针头位置和穿刺事件,准确率为85%。实验表明,与手工方法相比,导航和穿刺时间明显减少。我们的研究结果展示了将先进成像和深度学习集成到自动化显微外科任务中的潜力,为更安全、更可靠的RVC程序提供了一条途径,同时提高了精度和可重复性。
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引用次数: 0
FBG-based Shape-Sensing to Enable Lateral Deflection Methods of Autonomous Needle Insertion. 基于fbg的形状传感实现自主插针侧向偏转方法。
Dimitri A Lezcano, Iulian I Iordachita, Jin Seob Kim

In diagnosing and treating prostate cancer the flexible bevel tip needle insertion surgical technique is commonly used. Bevel tip needles experience asymmetric loading on the needle's tip, inducing natural bending of the needle and enabling control mechanisms for precise placement of the needle during surgery. Several methods leverage the needles natural bending to provide autonomous control of needle insertion for accurate needle placement in an effort to reduce excess tissue damage and improve patient outcomes from needle insertion intraventions. Moreover, control methods using lateral deflection of the needle intra-operatively to steer the needle during insertion have been studied and have shown promising results. Thus, to enable these autonomous control methods, real-time, intra-operative shape-sensing feedback is pivotal for optimal performance of the needle insertion control. This work presents an extension of our proven Lie-group theoretic shape-sensing model to handle lateral deflection of the needle during needle insertion and validate this extension with robotic needle insertions in phantom tissue using stereo vision as a ground truth. Furthermore, the system configuration for real-time shape-sensing is implemented using ROS 2, demonstrating average feedback frequency of 15 ± 8 Hz. Average needle shape errors realized from this extension under 1 mm, validating the shape-sensing models' extension.

在前列腺癌的诊断和治疗中,常用的是柔性斜尖插针手术技术。斜尖针头在针尖上承受不对称载荷,导致针头自然弯曲,并在手术过程中实现针头精确放置的控制机制。有几种方法利用针头的自然弯曲来提供针头插入的自主控制,以实现准确的针头放置,以减少多余的组织损伤,并改善针头插入静脉注射的患者预后。此外,在术中利用针的侧向偏转来引导针插入的控制方法也得到了研究,并显示出良好的结果。因此,为了实现这些自主控制方法,实时的术中形状感知反馈对于针插入控制的最佳性能至关重要。这项工作提出了我们已证明的李群理论形状传感模型的扩展,以处理针头插入过程中针头的横向偏转,并使用立体视觉作为基础事实验证机器人针头插入幻觉组织的扩展。此外,采用ROS 2实现了实时形状传感的系统配置,显示平均反馈频率为15±8 Hz。该扩展实现的平均针形误差小于1 mm,验证了形状感知模型的扩展。
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引用次数: 0
Simultaneous Super-resolution and Depth Estimation for Satellite Images Based on Diffusion Model. 基于扩散模型的卫星图像同步超分辨率和深度估计。
Yuwei Zhou, Yangming Lee

Satellite images provide an effective way to observe the earth surface on a large scale. 3D landscape models can provide critical structural information, such as forestry and crop growth. However, there has been very limited research to estimate the depth and the 3D models of the earth based on satellite images. LiDAR measurements on satellites are usually quite sparse. RGB images have higher resolution than LiDAR, but there has been little research on 3D surface measurements based on satellite RGB images. In comparison with in-situ sensing, satellite RGB images are usually low resolution. In this research, we explore the method that can enhance the satellite image resolution to generate super-resolution images and then conduct depth estimation and 3D reconstruction based on higher-resolution satellite images. Leveraging the strong generation capability of diffusion models, we developed a simultaneous diffusion model learning framework that can train diffusion models for both super-resolution images and depth estimation. With the super-resolution images and the corresponding depth maps, 3D surface reconstruction models with detailed landscape information can be generated. We evaluated the proposed methodology on multiple satellite datasets for both super-resolution and depth estimation tasks, which have demonstrated the effectiveness of our methodology.

卫星图像为大规模观测地表提供了一种有效途径。三维景观模型可以提供关键的结构信息,如林业和作物生长。然而,基于卫星图像估算地球深度和三维模型的研究非常有限。卫星上的激光雷达测量通常相当稀疏。RGB图像具有比激光雷达更高的分辨率,但基于卫星RGB图像的三维表面测量研究很少。与原位遥感相比,卫星RGB图像的分辨率通常较低。在本研究中,我们探索了通过提高卫星图像分辨率生成超分辨率图像的方法,然后基于更高分辨率的卫星图像进行深度估计和三维重建。利用扩散模型强大的生成能力,我们开发了一个同步扩散模型学习框架,可以同时训练超分辨率图像和深度估计的扩散模型。利用超分辨率图像和相应的深度图,可以生成包含详细景观信息的三维地表重建模型。我们在多个卫星数据集上对所提出的方法进行了超分辨率和深度估计任务的评估,证明了我们的方法的有效性。
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引用次数: 0
ODTFormer: Efficient Obstacle Detection and Tracking with Stereo Cameras Based on Transformer. ODTFormer:基于变压器的立体摄像机高效障碍物检测与跟踪。
Tianye Ding, Hongyu Li, Huaizu Jiang

Obstacle detection and tracking represent a critical component in robot autonomous navigation. In this paper, we propose ODTFormer, a Transformer-based model that addresses both obstacle detection and tracking problems. For the detection task, our approach leverages deformable attention to construct a 3D cost volume, which is decoded progressively in the form of voxel occupancy grids. We further track the obstacles by matching the voxels between consecutive frames. The entire model can be optimized in an end-to-end manner. Through extensive experiments on DrivingStereo and KITTI benchmarks, our model achieves state-of-the-art performance in the obstacle detection task. We also report comparable accuracy to state-of-the-art obstacle tracking models while requiring only a fraction of their computation cost, typically ten-fold to twenty-fold less. Our code is available on https://github.com/neu-vi/ODTFormer.

障碍物检测与跟踪是机器人自主导航的重要组成部分。在本文中,我们提出了ODTFormer,一个基于变压器的模型,解决了障碍物检测和跟踪问题。对于检测任务,我们的方法利用可变形的注意力来构建一个3D成本体,该成本体以体素占用网格的形式逐步解码。我们通过匹配连续帧之间的体素进一步跟踪障碍物。整个模型可以以端到端的方式进行优化。通过在DrivingStereo和KITTI基准上的大量实验,我们的模型在障碍物检测任务中达到了最先进的性能。我们还报告了与最先进的障碍物跟踪模型相当的准确性,而只需要其计算成本的一小部分,通常少10到20倍。我们的代码可以在https://github.com/neu-vi/ODTFormer上找到。
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引用次数: 0
Enhancing Surgical Precision in Autonomous Robotic Incisions via Physics-Based Tissue Cutting Simulation. 通过基于物理的组织切割模拟提高自主机器人切口的手术精度。
Jiawei Ge, Ethan Kilmer, Leila J Mady, Justin D Opfermann, Axel Krieger

In soft tissue surgeries, such as tumor resections, achieving precision is of utmost importance. Surgeons conventionally achieve this precision through intraoperative adjustments to the cutting plan, responding to deformations from tool-tissue interactions. This study examines the integration of physics-based tissue cutting simulations into autonomous robotic surgery to preoperatively predict and compensate for such deformations, aiming to improve surgical precision and reduce the necessity for dynamic adjustments during autonomous surgeries. This study adapts a real-to-sim-to-real workflow. Initially, the Autonomous System for Tumor Resection (ASTR) was employed to evaluate its accuracy in performing preoperatively intended incisions along the irregular contours of porcine tongue pseudotumors. Following this, a finite element analysis-based simulation, utilizing the Simulation Open Framework Architecture (SOFA), was developed and tuned to accurately mimic these tissue and incision interactions. Insights gained from this simulation were applied to refine the robot's path planning, ensuring a closer alignment of actual incisions with the initially intended surgical plan. The efficacy of this approach was validated by comparing surface incision precision on ex vivo porcine tongues, with the average absolute error reducing from 1.73mm to 1.46mm after applying simulation-driven path adjustments (p < 0.001). Additionally, our method not only demonstrated improvements in maintaining the intended cutting shapes and locations, with shape matching scores using Hu moments enhancing from 0.10 to 0.06 and centroid shifts decreasing from 2.09mm to 1.33mm, but it also potentially reduced the likelihood of adverse oncologic outcomes by preventing clinically suggested excessively close margins of 2.2mm. This feasibility study suggests that merging physics-based cutting simulations with autonomous robotic surgery could potentially lead to more accurate incisions.

在软组织手术中,如肿瘤切除,达到精确是最重要的。外科医生通常通过术中调整切割计划来达到这种精度,以应对工具与组织相互作用造成的变形。本研究探讨了将基于物理的组织切割模拟集成到自主机器人手术中,以在手术前预测和补偿此类变形,旨在提高手术精度并减少自主手术期间动态调整的必要性。本研究采用了真实到模拟到真实的工作流程。最初,采用肿瘤切除自主系统(ASTR)来评估其在猪舌假肿瘤不规则轮廓上进行术前预期切口的准确性。在此之后,利用仿真开放框架架构(SOFA)开发并调整了基于有限元分析的仿真,以准确模拟这些组织和切口的相互作用。从模拟中获得的见解被应用于改进机器人的路径规划,确保实际切口与最初预期的手术计划更接近。通过对离体猪舌表面切割精度的比较,验证了该方法的有效性,应用仿真驱动路径调整后,平均绝对误差从1.73mm减少到1.46mm (p < 0.001)。此外,我们的方法不仅在维持预期的切割形状和位置方面有所改善,使用Hu矩的形状匹配分数从0.10提高到0.06,质心偏移从2.09mm减少到1.33mm,而且还通过防止临床建议的2.2mm过近的边缘,潜在地降低了不良肿瘤结果的可能性。这项可行性研究表明,将基于物理的切割模拟与自主机器人手术相结合,可能会带来更精确的切口。
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引用次数: 0
Meta-Learning for Fast Adaptation in Intent Inferral on a Robotic Hand Orthosis for Stroke. 基于元学习的脑卒中机器人手矫形器意图区间快速适应研究。
Pedro Leandro La Rotta, Jingxi Xu, Ava Chen, Lauren Winterbottom, Wenxi Chen, Dawn Nilsen, Joel Stein, Matei Ciocarlie

We propose MetaEMG, a meta-learning approach for fast adaptation in intent inferral on a robotic hand orthosis for stroke. One key challenge in machine learning for assistive and rehabilitative robotics with disabled-bodied subjects is the difficulty of collecting labeled training data. Muscle tone and spasticity often vary significantly among stroke subjects, and hand function can even change across different use sessions of the device for the same subject. We investigate the use of meta-learning to mitigate the burden of data collection needed to adapt high-capacity neural networks to a new session or subject. Our experiments on real clinical data collected from five stroke subjects show that MetaEMG can improve the intent inferral accuracy with a small session- or subject-specific dataset and very few fine-tuning epochs. To the best of our knowledge, we are the first to formulate intent inferral on stroke subjects as a meta-learning problem and demonstrate fast adaptation to a new session or subject for controlling a robotic hand orthosis with EMG signals.

我们提出了一种元学习方法MetaEMG,用于快速适应脑卒中机器手部矫形器的意图神经。残障对象辅助和康复机器人的机器学习面临的一个关键挑战是收集标记训练数据的困难。在中风患者中,肌肉张力和痉挛往往有显著差异,手部功能甚至可能在同一受试者使用该设备的不同阶段发生变化。我们研究了使用元学习来减轻高容量神经网络适应新会话或主题所需的数据收集负担。我们对五名中风受试者的真实临床数据进行了实验,结果表明MetaEMG可以通过小的会话或受试者特定数据集和很少的微调时间来提高意图区间的准确性。据我们所知,我们是第一个将中风受试者的意图区间作为一个元学习问题,并展示了用肌电图信号控制机械手矫形器对新会话或主题的快速适应。
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引用次数: 0
Thermal Ablation Therapy Control with Tissue Necrosis-driven Temperature Feedback Enabled by Neural State Space Model with Extended Kalman Filter. 基于扩展卡尔曼滤波的神经状态空间模型实现组织坏死驱动温度反馈的热消融治疗控制。
Ryo Murakami, Satoshi Mori, Haichong K Zhang

Thermal ablation therapy is a major minimally invasive treatment. One of the challenges is that the targeted region and therapeutic progression are often invisible to clinicians, requiring feedback provided in numerical information or imaging. Several emerging imaging modalities offer visualization of the ablation-induced necrosis formation; however, relying solely on necrosis monitoring can result in tissue overheating and endangering patients. Some of the necrosis monitoring modalities are known for their capabilities in temperature sensing, but the principles on which they are based have several limitations, such as sensitivity to the tissue motion and their environment. In this study, we propose a necrosis progression-based temperature estimation technique as an added safety feature for avoiding overheating. This model-based method does not require additional sensing hardware. It is designed to work as an independent estimator or a complimentary estimation component with other thermometers for improved robustness. For this objective, the Neural State Space model is used to approximate the ablation therapy, whose theoretical models involve nonlinear partial differential equations. Then, the Extended Kalman Filter is designed based on the model. The simulation study shows the estimation module robustly estimates the tissue temperature under several types of noise. The maximum estimation error observed before terminating ablation was around 1 °C, and the desired safety feature was successfully demonstrated. The estimator is expected to be used in a variety of necrosis monitoring modalities to guarantee more precise and safer treatment. More ambitiously, the architecture with the Neural State Space model and Extended Kalman Filter is generalizable to other medical/biological procedures involving nonlinear and patient/environment-specific physics and even to procedures having no reliable theoretical models.

热消融治疗是一种主要的微创治疗方法。其中一个挑战是,目标区域和治疗进展往往是不可见的临床医生,需要在数字信息或成像提供反馈。几种新兴的成像方式提供了消融引起的坏死形成的可视化;然而,仅仅依靠坏死监测可能导致组织过热,危及患者。一些坏死监测模式以其温度传感能力而闻名,但它们所基于的原理有一些局限性,例如对组织运动及其环境的敏感性。在这项研究中,我们提出了一种基于坏死进展的温度估计技术,作为避免过热的附加安全功能。这种基于模型的方法不需要额外的传感硬件。它被设计成一个独立的估计器或与其他温度计的互补估计组件,以提高鲁棒性。为此,采用神经状态空间模型来近似消融治疗,其理论模型涉及非线性偏微分方程。在此基础上设计了扩展卡尔曼滤波器。仿真研究表明,该估计模块能在多种噪声条件下对组织温度进行鲁棒估计。在终止烧蚀前观察到的最大估计误差约为1°C,并且成功地证明了所需的安全特性。估计器有望用于各种坏死监测模式,以保证更精确和更安全的治疗。更雄心勃勃的是,具有神经状态空间模型和扩展卡尔曼滤波器的体系结构可推广到其他涉及非线性和患者/环境特定物理的医疗/生物程序,甚至可以推广到没有可靠理论模型的程序。
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引用次数: 0
Volitional EMG Control Enables Stair Climbing with a Robotic Powered Knee Prosthesis. 利用机器人动力膝关节假体实现自愿肌电图控制爬楼梯
Suzi Creveling, Marissa Cowan, Liam M Sullivan, Lukas Gabert, Tommaso Lenzi

Existing controllers for robotic powered prostheses regulate the prosthesis speed, timing, and energy generation using predefined position or torque trajectories. This approach enables climbing stairs step-over-step. However, it does not provide amputees with direct volitional control of the robotic prosthesis, a functionality necessary to restore full mobility to the user. Here we show that proportional electromyographic (EMG) control of the prosthesis knee torque enables volitional control of a powered knee prosthesis during stair climbing. The proposed EMG controller continuously regulates knee torque based on activation of the residual hamstrings, measured using a single EMG electrode located within the socket. The EMG signal is mapped to a desired knee flexion/extension torque based on the prosthesis knee position, the residual limb position, and the interaction with the ground. As a result, the proposed EMG controller enabled an above-knee amputee to climb stairs at different speeds, while carrying additional loads, and even backwards. By enabling direct, volitional control of powered robotic knee prostheses, the proposed EMG controller has the potential to improve amputee mobility in the real world.

现有的机器人动力假肢控制器通过预定义的位置或扭矩轨迹来调节假肢的速度、时间和能量产生。这种方法可以实现逐级爬楼梯。然而,它并不能为截肢者提供对机器人假肢的直接意志控制,而这是恢复使用者完全活动能力所必需的功能。在这里,我们展示了对假肢膝关节扭矩的比例肌电图(EMG)控制,可在爬楼梯时实现对动力膝关节假肢的自主控制。所提出的肌电图控制器可根据残余腘绳肌的激活情况持续调节膝关节扭矩,而残余腘绳肌的激活情况是通过位于插座内的单个肌电图电极测量的。根据假肢膝盖位置、残余肢体位置以及与地面的相互作用,将 EMG 信号映射到所需的膝关节屈/伸扭矩。因此,所提出的肌电图控制器使膝上截肢者能够以不同的速度爬楼梯,同时还能承受额外的负荷,甚至是向后爬。通过实现对动力机器人膝关节假肢的直接、自愿控制,所提出的肌电图控制器有可能改善截肢者在现实世界中的活动能力。
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引用次数: 0
Analytical Computation of the Contact Force Jacobian for MRI-Actuated Robotic Catheter. 磁共振成像机器人导管接触力雅各布的分析计算
Yuttana Itsarachaiyot, Ran Hao, M Cenk Çavuşoğlu

Contact force Jacobian relates the changes in the contact force to the changes in the actuation of a robotic catheter in contact with a surface. In this paper, we present an analytical method for calculating the contact force Jacobian for the Cosserat rod model of an MRI-actuated robotic catheter. First, the Cosserat rod model of the MRI-actuated robotic catheter under tip contact position constraint is introduced. For the analytical derivation of contact force Jacobian, the initial value problem parameter derivatives are defined and calculated analytically. Finally, simulation results show that the presented analytical method calculates the contact force Jacobian in significantly shorter computation time with comparable accuracy, compared to direct numerical computation.

接触力雅各布系数将接触力的变化与机器人导管在接触表面时的驱动力变化联系起来。本文提出了一种分析方法,用于计算磁共振成像致动机器人导管的 Cosserat 杆模型的接触力雅各布。首先,介绍在尖端接触位置约束下的核磁共振成像机器人导管的 Cosserat 杆模型。为了分析推导接触力雅各布,定义了初值问题参数导数并进行了分析计算。最后,仿真结果表明,与直接数值计算相比,所提出的分析方法计算接触力雅各布的时间大大缩短,精度相当。
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引用次数: 0
Effects of Personalization on Gait-State Tracking Performance Using Extended Kalman Filters. 个性化对使用扩展卡尔曼滤波器的步态跟踪性能的影响
José A Montes-Pérez, Gray Cortright Thomas, Robert D Gregg

Emerging partial-assistance exoskeletons can enhance able-bodied performance and aid people with pathological gait or age-related immobility. However, every person walks differently, which makes it difficult to directly compute assistance torques from joint kinematics. Gait-state estimation-based controllers use phase (normalized stride time) and task variables (e.g., stride length and ground inclination) to parameterize the joint torques. Using kinematic models that depend on the gait-state, prior work has used an Extended Kalman filter (EKF) to estimate the gait-state online. However, this EKF suffered from kinematic errors since it used a subject-independent measurement model, and it is still unknown how personalization of this measurement model would reduce gait-state tracking error. This paper quantifies how much gait-state tracking improvement a personalized measurement model can have over a subject-independent measurement model when using an EKF-based gait-state estimator. Since the EKF performance depends on the measurement model covariance matrix, we tested on multiple different tuning parameters. Across reasonable values of tuning parameters that resulted in good performance, personalization improved estimation error on average by 8.5 ± 13.8% for phase (mean ± standard deviation), 27.2 ± 8.1% for stride length, and 10.5 ± 13.5% for ground inclination. These findings support the hypothesis that personalization of the measurement model significantly improves gait-state estimation performance in EKF based gait-state tracking (P0.05), which could ultimately enable reliable responses to faster human gait changes.

新出现的部分辅助外骨骼可以提高健全人的表现,并帮助有病态步态或因年老而行动不便的人。然而,每个人的行走方式都不尽相同,因此很难根据关节运动学直接计算辅助力矩。基于步态估计的控制器使用相位(归一化步幅时间)和任务变量(如步幅长度和地面倾斜度)来确定关节扭矩的参数。利用依赖于步态的运动学模型,先前的工作使用了扩展卡尔曼滤波器(EKF)来在线估计步态。然而,由于这种 EKF 使用的是与受试者无关的测量模型,因此存在运动学误差,而且这种测量模型的个性化如何减少步态跟踪误差仍是未知数。本文量化了在使用基于 EKF 的步态估计器时,个性化测量模型比与受试者无关的测量模型能在多大程度上改善步态跟踪。由于 EKF 的性能取决于测量模型协方差矩阵,我们对多个不同的调整参数进行了测试。在能带来良好性能的合理调谐参数值范围内,个性化平均改善了相位(平均值±标准偏差)的估计误差 8.5 ± 13.8%、步长的估计误差 27.2 ± 8.1%、地面倾斜的估计误差 10.5 ± 13.5%。这些发现支持了这样的假设,即测量模型的个性化能显著提高基于 EKF 的步态跟踪的步态估计性能(P≪0.05),最终能对更快的人体步态变化做出可靠的响应。
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引用次数: 0
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Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems
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