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Displacement of intraorbital ferromagnetic foreign bodies induced by magnetic resonance imaging: Quantification using an animal model. 磁共振成像诱导眶内铁磁异物移位:动物模型定量。
Pub Date : 2026-01-15 eCollection Date: 2025-12-01 DOI: 10.1016/j.redii.2025.100064
Camille Cathelineau, Marwane Ghemame, Antoine Le Boëdec, Béatrice Carsin-Nicol, Hervé Saint-Jalmes, Pierre-Antoine Éliat, Frédéric Mouriaux, Jean-Christophe Ferré

Rationale and objectives: The presence of ferromagnetic foreign bodies in the intraorbital area, eyelids, or intraorbital fat of an examined subject represents a contraindication to magnetic resonance imaging (MRI). We sought to measure the displacement of one or two intraocular and intraorbital ferromagnetic foreign bodies in ex vivo porcine heads following 1.5 T MRI scan compared to 5-min walk test.

Materials and methods: In this ex-vivo controlled laboratory study, a total of 48 1-, 2-, and 4-mm steel balls were surgically implanted into suprachoroidal, intraorbital fat, intrapalpebral, and intravitreal locations of 36 fresh porcine heads. Ferromagnetic foreign bodies displacement was measured by comparing computed tomography scan before and after both a 5-min walk test to simulate handling-related movement and 1.5 T MRI scan. Comparison of groups was performed using the non-parametric Mann-Whitney-Wilcoxon test.

Results: Global median displacement after 5-min walk test was 0.8 mm. Compared to the control group, the ferromagnetic foreign bodies displacement after MRI was significant for the suprachoroidal location with single ferromagnetic foreign body (2.3 mm, p = 0.0282), and for the intravitreal location with single ferromagnetic foreign body (4.5 mm, p = 0.0282) and double ferromagnetic foreign bodies (5.0 mm, p = 0.0282). Compared to the control group, ferromagnetic foreign body displacement after MRI was significant for the double 2-mm ferromagnetic foreign bodies (2.2 mm, p = 0.0130), single 4-mm ferromagnetic foreign body (4.9 mm, p = 0.0107), and double 4-mm ferromagnetic foreign bodies (9.0 mm, p = 0.0084).

Conclusion: Ferromagnetic foreign body displacements after 1.5 T magnetic field exposition were not significant for extraocular intrapalpebral and intraorbital fat locations. Neither were there significant displacements for 1-mm ferromagnetic foreign body, irrespective of the location. On the other hand, the presence of two objects increased the displacement of 2- and 4-mm ferromagnetic foreign bodies.

理由和目的:在被检查对象的眶内区域、眼睑或眶内脂肪中存在铁磁性异物代表磁共振成像(MRI)的禁忌症。与5分钟步行测试相比,我们试图在1.5 T MRI扫描后测量离体猪头中一个或两个眼内和眶内铁磁异物的位移。材料和方法:在本离体对照实验室研究中,共将48个1、2和4毫米钢球手术植入36个新鲜猪头的脉络膜上、眶内脂肪、睑内和玻璃体内。通过比较模拟处理相关运动的5分钟步行测试和1.5 T MRI扫描前后的计算机断层扫描来测量铁磁性异物的位移。组间比较采用非参数Mann-Whitney-Wilcoxon检验。结果:5分钟步行试验后的整体中位位移为0.8 mm。与对照组相比,单铁磁异物在脉络膜上定位(2.3 mm, p = 0.0282)、单铁磁异物在玻璃体内定位(4.5 mm, p = 0.0282)和双铁磁异物在玻璃体内定位(5.0 mm, p = 0.0282) MRI后铁磁异物移位显著。与对照组相比,MRI后双2-mm铁磁异物(2.2 mm, p = 0.0130)、单4-mm铁磁异物(4.9 mm, p = 0.0107)、双4-mm铁磁异物(9.0 mm, p = 0.0084)的铁磁异物位移显著。结论:1.5 T磁场暴露后铁磁异物移位对眼外、睑内、眶内脂肪部位无显著影响。无论位置如何,1毫米铁磁异物也没有明显的位移。另一方面,两个物体的存在增加了2和4毫米铁磁异物的位移。
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引用次数: 0
Enhancing knee MRI bone marrow lesion detection with artificial intelligence: An external validation study 人工智能增强膝关节MRI骨髓病变检测:一项外部验证研究
Pub Date : 2025-08-14 DOI: 10.1016/j.redii.2025.100063
Kevin Maarek , Philippine Cordelle , Tom Vesoul , Pascal Zille , Gaspard d'Assignies , Antoine Feydy , Guillaume Herpe

Background

Magnetic resonance imaging (MRI) is a sensitive imaging modality for identifying knee bone marrow edema, a significant biomarker in osteoarthritis and injury assessment. The precision of bone marrow edema detection is contingent upon the radiologist's expertise, and segmentation efficiency demands substantial time.

Purpose

This study evaluated artificial intelligence's (AI) impact on enhancing general radiologists' diagnostic accuracy for bone marrow edema detection in knee MRI.

Materials and methods

A multicenter, multireader, multicase methodology was used in this retrospective diagnostic study, which relied on an external dataset of 198 examinations. Mean age was 46 years with a standard deviation (SD) of 15.8 years and a female/male ratio of 49 %/51 %.
An AI algorithm from the AI solution Keros, comprising three orientation-specific 3D-UNet models, was deployed for bone marrow edema segmentation on T2/proton density with fat suppression sequences.
The ground truth was set by expert musculoskeletal radiologists.
The purpose was to externally validate the AI algorithm and compare the performance and speed of bone marrow edema identification by less experienced radiologists when using the algorithm versus not using it

Results

A total of 184 patients were included. With AI, readers’ sensitivity for bone marrow edema detection significantly increased by 6.1 % from 79.3 % without AI (95 % confidence interval [95 % CI]: 77.2–80.3 %) to 85.4 % (95 % CI: 84–86.2 %) with AI (p = 0). Specificity significantly increased by 5 % with AI assistance, reaching 93.9 % (95 % CI: 93.7–94.6 %) from 88.9 % (95 % CI: 88.6–89.4 %) (p = 0). Reading times were reduced by 42 % (0.66 min per exam, p = 3.81e-41).

Conclusion

AI significantly increased the sensitivity and specificity of bone marrow edema detection for general radiologists and shortened the reading process. AI-assisted detection of bone edema in the knee also opens up new perspectives for the longitudinal monitoring of patients with knee osteoarthritis.
磁共振成像(MRI)是识别膝关节骨髓水肿的一种敏感成像方式,是骨关节炎和损伤评估的重要生物标志物。骨髓水肿检测的准确性取决于放射科医生的专业知识,分割效率需要大量的时间。目的本研究评估人工智能(AI)对提高普通放射科医生膝关节MRI骨髓水肿诊断准确性的影响。材料和方法本回顾性诊断研究采用多中心、多阅读器、多病例方法,依赖于198项检查的外部数据集。平均年龄46岁,标准差(SD) 15.8岁,男女比例为49% / 51%。来自AI解决方案Keros的AI算法,包括三个定向3D-UNet模型,采用脂肪抑制序列对T2/质子密度进行骨髓水肿分割。最基本的事实是由肌肉骨骼放射专家确定的。目的是对人工智能算法进行外部验证,并比较经验不足的放射科医生在使用该算法与不使用该算法时识别骨髓水肿的性能和速度。结果共纳入184例患者。使用人工智能后,读者对骨髓水肿检测的敏感性从未使用人工智能的79.3%(95%可信区间[95% CI]: 77.2 - 80.3%)显著提高到使用人工智能后的85.4% (95% CI: 84 - 86.2%),提高了6.1% (p = 0)。人工智能辅助下特异性显著提高5%,从88.9% (95% CI: 88.6 - 89.4%)达到93.9% (95% CI: 93.7 - 94.6%) (p = 0)。阅读时间减少42%(每次考试0.66分钟,p = 3.81e-41)。结论人工智能显著提高了普通放射科医师骨髓水肿检测的敏感性和特异性,缩短了读取过程。人工智能辅助检测膝关节骨水肿也为膝关节骨关节炎患者的纵向监测开辟了新的视角。
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引用次数: 0
In vivo percutaneous microwave ablation with ECO system in swine kidney and liver: comparison of ablation-zone size to manufacturer predictions and assessment of new antenna design ECO系统在猪肾脏和肝脏的体内经皮微波消融:消融区大小与制造商预测的比较和新天线设计的评估
Pub Date : 2025-05-27 DOI: 10.1016/j.redii.2025.100061
Théo Bonnefoy , Georges Tarris , Kévin Guillen , Olivia Poupardin , Olivier Chevallier , Ludwig Serge Aho Glele , Jean-Michel Correas , Romaric Loffroy

Aim

Percutaneous microwave ablation is an effective and minimally invasive treatment for small tumors. To achieve local disease control, the entire tumor and a surrounding safety margin must be destroyed. Power and application time are chosen based on manufacturer-provided data, usually obtained from ex vivo animal models. However, ex vivo tissues differ from in vivo condition due to compositional changes and absence of heat dissipation by blood flow. This study aimed to compare in vivo ablation zone sizes in swine with those predicted by the device manufacturer.

Methods

Five pigs underwent 40 microwave ablation procedures using various power-time-organ combinations; 18 hepatic and 20 renal zones were evaluable. All procedures were performed with devices from a single manufacturer (ECO Microwave System Co, Nanjing, China). After euthanasia, the ablation zones were excised and sliced. For each ablation, the slice showing the largest dimensions was selected to measure x and y diameters and used to compute the ablated surface area.

Results

For seven of eight power-time-organ combinations, significant differences were found between predicted and measured surface areas (p < 0.05), with deviations ranging from –45 % to +54 %. The overall mean absolute differences between measured and predicted ablation sizes in the x and y dimensions and the ablation surface area were 7.6 ± 4.6 mm (28 % ± 19 %), 5.8 ± 4.3 mm (18 % ± 13 %) and 273 ± 210 mm² (39 % ± 34 %), respectively.

Conclusion

Manufacturer-provided predictive data for microwave ablation zone size may lack reliability. Intraoperative and postoperative monitoring of ablation zone size is crucial to ensure complete tumor destruction with adequate margins.
经皮微波消融术是一种有效的微创小肿瘤治疗方法。为了实现局部疾病控制,必须破坏整个肿瘤和周围的安全边际。功率和应用时间的选择基于制造商提供的数据,通常从离体动物模型中获得。然而,离体组织与体内组织不同,因为组织成分发生了变化,并且没有血流散热。本研究旨在比较猪体内消融区大小与设备制造商预测的大小。方法5头猪采用不同功率-时间-器官组合进行40次微波消融术;18个肝区和20个肾区可评价。所有操作均由同一制造商(ECO Microwave System Co, Nanjing, China)提供。安乐死后,切除消融区并切片。对于每次烧蚀,选择显示最大尺寸的切片来测量x和y直径,并用于计算烧蚀表面积。结果对于8个功率-时间-器官组合中的7个,预测表面积与测量表面积之间存在显著差异(p <;0.05),偏差范围从- 45%到+ 54%。实测和预测的消融尺寸在x和y尺寸及消融表面积上的总体平均绝对差值分别为7.6±4.6 mm(28%±19%)、5.8±4.3 mm(18%±13%)和273±210 mm²(39%±34%)。结论厂商提供的微波消融区大小预测数据缺乏可靠性。术中及术后监测消融区大小对于确保肿瘤的完全破坏和足够的边缘是至关重要的。
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引用次数: 0
Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions 一种深度学习图像重建算法对图像质量和肺实体病变检测的影响
Pub Date : 2025-05-27 DOI: 10.1016/j.redii.2025.100062
Joël Greffier , Maxime Pastor , Quentin Durand , Renaud Sales , Chris Serrand , Jean-Paul Beregi , Djamel Dabli , Julien Frandon

Purpose

To compare the impact of a deep-learning image reconstruction algorithm (Precise Image) with an iterative reconstruction algorithm on image quality and detection of solid lung lesions in chest CT images.

Methods

All consecutive patients with at least one solid lung lesion diagnosed between December 2021 and February 2022 were retrospectively included. Images were reconstructed using Level 4 of the iterative reconstruction algorithm (i4) and the Standard/Smooth/Smoother levels of the deep-learning image reconstruction algorithm. Mean attenuation and standard deviation were measured by placing regions of interest in fat, muscle, trachea and solid lung lesions. The contrast-to-noise ratio between the lesion and the trachea was computed. Two radiologists assessed image noise and image smoothness, overall image quality and confidence diagnostic level using Likert scales. One radiologist also measured the large axis of the largest lesion. Statistical analyses was performed to compare outcomes obtained with the different algorithms.

Results

Thirty patients with a mean age of 70.0 ± 9.0 years (17 men) were included. The mean CTDIvol was 6.3 ± 2.1 mGy. For all tissues, the contrast-to-noise ratio was similar for i4 and Standard level (p > 0.05) but increased significantly with other deep-learning image reconstruction levels compared to i4 (p < 0.05) and increased significantly from Standard to Smoother. Radiologists rated the image noise with a similar score between i4 and Standard level but decreased significantly between i4 and other deep-learning image reconstruction levels (p < 0.05) and from Standard to Smoother levels (p < 0.01). Overall image quality score were highest for the Smooth and Smoother levels.

Conclusion

Smooth and Smoother levels may now be used in clinical practice for chest CT acquisitions in solid lung lesion follow-up.
目的比较深度学习图像重建算法(Precise image)与迭代重建算法对胸部CT图像质量和肺实性病变检测的影响。方法回顾性分析所有在2021年12月至2022年2月期间诊断为至少一种实性肺病变的连续患者。使用迭代重建算法的Level 4 (i4)和深度学习图像重建算法的Standard/Smooth/Smooth级别重建图像。通过在脂肪、肌肉、气管和实体肺病变中放置感兴趣的区域来测量平均衰减和标准偏差。计算病变与气管的噪比。两名放射科医生使用李克特量表评估图像噪声和图像平滑度,整体图像质量和置信度诊断水平。一位放射科医生还测量了最大病变的大轴。统计分析比较不同算法得到的结果。结果入选患者30例,平均年龄70.0±9.0岁,男性17例。平均CTDIvol为6.3±2.1 mGy。对于所有组织,i4和标准水平的对比噪声比相似(p >;0.05),但与其他深度学习图像重建水平相比显著增加(p <;0.05),从标准到平滑显著增加。放射科医生对图像噪声的评分在i4和标准水平之间相似,但在i4和其他深度学习图像重建水平之间显著下降(p <;0.05),从标准水平到平滑水平(p <;0.01)。整体图像质量得分最高的是平滑和平滑水平。结论在实性肺病变随访中,平滑水平可用于胸部CT扫描。
{"title":"Impact of a deep-learning image reconstruction algorithm on image quality and detection of solid lung lesions","authors":"Joël Greffier ,&nbsp;Maxime Pastor ,&nbsp;Quentin Durand ,&nbsp;Renaud Sales ,&nbsp;Chris Serrand ,&nbsp;Jean-Paul Beregi ,&nbsp;Djamel Dabli ,&nbsp;Julien Frandon","doi":"10.1016/j.redii.2025.100062","DOIUrl":"10.1016/j.redii.2025.100062","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the impact of a deep-learning image reconstruction algorithm (Precise Image) with an iterative reconstruction algorithm on image quality and detection of solid lung lesions in chest CT images.</div></div><div><h3>Methods</h3><div>All consecutive patients with at least one solid lung lesion diagnosed between December 2021 and February 2022 were retrospectively included. Images were reconstructed using Level 4 of the iterative reconstruction algorithm (i4) and the Standard/Smooth/Smoother levels of the deep-learning image reconstruction algorithm. Mean attenuation and standard deviation were measured by placing regions of interest in fat, muscle, trachea and solid lung lesions. The contrast-to-noise ratio between the lesion and the trachea was computed. Two radiologists assessed image noise and image smoothness, overall image quality and confidence diagnostic level using Likert scales. One radiologist also measured the large axis of the largest lesion. Statistical analyses was performed to compare outcomes obtained with the different algorithms.</div></div><div><h3>Results</h3><div>Thirty patients with a mean age of 70.0 ± 9.0 years (17 men) were included. The mean CTDI<sub>vol</sub> was 6.3 ± 2.1 mGy. For all tissues, the contrast-to-noise ratio was similar for i4 and Standard level (<em>p</em> &gt; 0.05) but increased significantly with other deep-learning image reconstruction levels compared to i4 (<em>p</em> &lt; 0.05) and increased significantly from Standard to Smoother. Radiologists rated the image noise with a similar score between i4 and Standard level but decreased significantly between i4 and other deep-learning image reconstruction levels (<em>p</em> &lt; 0.05) and from Standard to Smoother levels (<em>p</em> &lt; 0.01). Overall image quality score were highest for the Smooth and Smoother levels.</div></div><div><h3>Conclusion</h3><div>Smooth and Smoother levels may now be used in clinical practice for chest CT acquisitions in solid lung lesion follow-up.</div></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"14 ","pages":"Article 100062"},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep learning reconstruction in biparametric prostate MRI: Impact on qualitative and radiomics analyses 双参数前列腺MRI的深度学习重建:对定性和放射组学分析的影响
Pub Date : 2025-05-22 DOI: 10.1016/j.redii.2025.100059
Jérémy Dana , Evan McNabb , Juan Castro , Ibtisam Al-Qanoobi , Yoshie Omiya , Kenny Ah-Lan , Véronique Fortier , Giovanni Artho , Caroline Reinhold , Simon Gauvin

Objective

To assess the impact of a commercially available deep learning reconstruction (DLR) algorithm on qualitative and radiomics analyses in prostate MRI.

Methods

This single-centre retrospective cohort included 25 consecutive patients who underwent a prostate MRI (1.5 T) in 2022. T2-weighted (T2WI), diffusion-weighted (DWI; b = 50, 1000, extrapolated 2000 s/mm2) and apparent diffusion coefficient (ADC) images were reconstructed using DLR and standard (non-DLR) techniques. The two sets were mixed and blind-reviewed independently by six radiologists. Images were qualitatively scored according to PI-QUAL score, overall image quality, diagnostic confidence, anatomical conspicuity, artifact, and noise. Transition and peripheral zones were segmented and radiomics features extracted from region-of-interests using Pyradiomics package. Qualitative criteria and radiomics were compared using a pairwise Wilcoxon signed-rank test.

Results

PI-QUAL score was not significantly different (p = 0.32). Overall image quality was not significantly different (p = 0.21 on T2WI and 0.56 on DWI/ADC). Noise was lower on DLR images for T2WI (p < 0.01) and DWI/ADC (p = 0.04). Diagnostic confidence in excluding clinically significant cancer (PI-RADS ≥ 3) in the transition zone was lower with DLR images (p = 0.02). In the transition zone, 89/93 (96 %) of the radiomics features were significantly different between non-DLR and DLR images on T2WI, 68/93 (73 %) on DWI b-2000 s/mm2, and 55/93 (59 %) on ADC images. In the peripheral zone, 91/93 (98 %) were significantly different on T2WI, 50/93 (54 %) on DWI b-2000 s/mm2, and 70/93 (75 %) on ADC images.

Conclusion

Radiomics features were significantly different on DLR images which should encourage caution for clinical and research purposes. DLR algorithm decreases noise while preserving overall image quality.
目的评估商用深度学习重建(DLR)算法对前列腺MRI定性和放射组学分析的影响。方法该单中心回顾性队列包括25例于2022年接受前列腺MRI (1.5 T)检查的连续患者。t2加权(T2WI),扩散加权(DWI;b = 50, 1000,外推2000 s/mm2)和表观扩散系数(ADC)图像重建使用DLR和标准(非DLR)技术。这两组数据由6名放射科医生进行混合和独立盲检。根据PI-QUAL评分、总体图像质量、诊断置信度、解剖显著性、伪影和噪声对图像进行定性评分。利用Pyradiomics软件包对过渡区和外围区进行分割,提取感兴趣区域的放射组学特征。定性标准和放射组学采用两两Wilcoxon符号秩检验进行比较。结果pi - qual评分差异无统计学意义(p = 0.32)。总体图像质量差异无统计学意义(T2WI p = 0.21, DWI/ADC p = 0.56)。T2WI的DLR图像噪声较低(p <;DWI/ADC (p = 0.04)。DLR影像排除过渡区临床显著癌(PI-RADS≥3)的诊断置信度较低(p = 0.02)。在过渡区,T2WI非DLR影像与DLR影像的放射组学特征差异有89/93 (96%),DWI b-2000 s/mm2影像的放射组学特征差异有68/93 (73%),ADC影像的放射组学特征差异有55/93(59%)。在周围区,T2WI呈91/93 (98%),DWI b-2000 s/mm2呈50/93 (54%),ADC呈70/93(75%)。结论放射组学特征在DLR图像上有显著差异,临床和研究应谨慎。DLR算法在保持整体图像质量的同时降低了噪声。
{"title":"Deep learning reconstruction in biparametric prostate MRI: Impact on qualitative and radiomics analyses","authors":"Jérémy Dana ,&nbsp;Evan McNabb ,&nbsp;Juan Castro ,&nbsp;Ibtisam Al-Qanoobi ,&nbsp;Yoshie Omiya ,&nbsp;Kenny Ah-Lan ,&nbsp;Véronique Fortier ,&nbsp;Giovanni Artho ,&nbsp;Caroline Reinhold ,&nbsp;Simon Gauvin","doi":"10.1016/j.redii.2025.100059","DOIUrl":"10.1016/j.redii.2025.100059","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the impact of a commercially available deep learning reconstruction (DLR) algorithm on qualitative and radiomics analyses in prostate MRI.</div></div><div><h3>Methods</h3><div>This single-centre retrospective cohort included 25 consecutive patients who underwent a prostate MRI (1.5 T) in 2022. T2-weighted (T2WI), diffusion-weighted (DWI; b = 50, 1000, extrapolated 2000 s/mm<sup>2</sup>) and apparent diffusion coefficient (ADC) images were reconstructed using DLR and standard (non-DLR) techniques. The two sets were mixed and blind-reviewed independently by six radiologists. Images were qualitatively scored according to PI-QUAL score, overall image quality, diagnostic confidence, anatomical conspicuity, artifact, and noise. Transition and peripheral zones were segmented and radiomics features extracted from region-of-interests using Pyradiomics package. Qualitative criteria and radiomics were compared using a pairwise Wilcoxon signed-rank test.</div></div><div><h3>Results</h3><div>PI-QUAL score was not significantly different (<em>p</em> = 0.32). Overall image quality was not significantly different (<em>p</em> = 0.21 on T2WI and 0.56 on DWI/ADC). Noise was lower on DLR images for T2WI (<em>p</em> &lt; 0.01) and DWI/ADC (<em>p</em> = 0.04). Diagnostic confidence in excluding clinically significant cancer (PI-RADS ≥ 3) in the transition zone was lower with DLR images (p = 0.02). In the transition zone, 89/93 (96 %) of the radiomics features were significantly different between non-DLR and DLR images on T2WI, 68/93 (73 %) on DWI b-2000 s/mm<sup>2</sup>, and 55/93 (59 %) on ADC images. In the peripheral zone, 91/93 (98 %) were significantly different on T2WI, 50/93 (54 %) on DWI b-2000 s/mm<sup>2</sup>, and 70/93 (75 %) on ADC images.</div></div><div><h3>Conclusion</h3><div>Radiomics features were significantly different on DLR images which should encourage caution for clinical and research purposes. DLR algorithm decreases noise while preserving overall image quality.</div></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"14 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144116124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrodissection in microwave ablation: the effectiveness of 0.9 % NaCl versus 5 % dextrose in an ex vivo experimental set-up 微波消融中的氢解剖:在离体实验装置中0.9% NaCl与5%葡萄糖的有效性
Pub Date : 2025-05-20 DOI: 10.1016/j.redii.2025.100060
Gonnie C.M. van Erp , Pim Hendriks , Sophie A. van den Hurk , Hannah F. Winder , Willemijn P.M. Scholtes , Lara B.E.M. De Bats , Jouke Dijkstra , Mark C. Burgmans

Purpose

To compare the effectiveness of hydrodissection using 0.9 % NaCl (saline) or 5 % dextrose in water during microwave ablation at different hydrodissection fluid thicknesses, in an ex vivo experimental set-up.

Methods

Two porcine liver parts were placed in a plastic container simulating a superficial liver ablation with adjacent tissue. The space between the livers was filled with either saline or 5 % dextrose in water. Microwave ablation was performed 4 min at 100 W, at 15 mm from the liver surface. Three thermocouples were used to determine the heat propagation: (1) between the microwave ablation antenna and liver surface; (2) 5 mm from the surface of the adjacent tissue; (3) 15 mm from the surface of the adjacent tissue. Forty experiments were performed using hydrodissection fluid thicknesses ranging from 1 to 10 mm. The maximum temperature increase for each thermocouple was determined. A Spearman’s correlation analysis assessed the relationship between the hydrodissection fluid thickness (in millimeters) and the temperature increase (in degrees Celsius) per fluid.

Results

At 5 mm within the adjacent tissue, use of 1 mm hydrodissection fluid thickness with 5 % dextrose in water resulted in less temperature increase (4.6 °C) compared to saline (6.8 °C). Additionally, at this distance, a negative correlation was observed between hydrodissection fluid thickness and temperature increase for both saline hydrodissection (r(18) = −0.96, p < 0.001) and 5 % dextrose in water hydrodissection (r(18) = -0.81, p < 0.001), which differs significantly (p = 0.011).

Conclusion

Results from this experimental ex vivo study suggest that 5 % dextrose in water may protect adjacent critical structures better from heating during microwave ablation than saline.
目的在离体实验装置中,比较0.9% NaCl(生理盐水)和5%葡萄糖水溶液在不同水解剖液厚度下微波消融时的效果。方法将2个猪肝部位置于塑料容器中,模拟肝脏浅表消融。用生理盐水或5%葡萄糖水填充肝脏之间的空隙。在距肝表面15mm处,100 W微波消融4分钟。采用三个热电偶来测定热传播:(1)微波消融天线与肝脏表面之间的热传播;(2)距邻近组织表面5mm;(3)离邻近组织表面15mm。采用1至10毫米的液体厚度进行了40次实验。确定了每个热电偶的最大温升。Spearman的相关性分析评估了水力分解液厚度(单位为毫米)与每种液体的温度升高(单位为摄氏度)之间的关系。结果在5 mm的邻近组织内,使用1 mm厚度的水解剖液加5%的葡萄糖,与盐水(6.8°C)相比,温度升高(4.6°C)较小。此外,在这一距离上,盐水水解液厚度与温度升高呈负相关(r(18) = - 0.96, p <;0.001)和5%葡萄糖在水水解中的作用(r(18) = -0.81, p <;0.001),差异显著(p = 0.011)。结论体外实验结果表明,5%葡萄糖水溶液对微波消融过程中邻近关键结构的保护作用优于生理盐水。
{"title":"Hydrodissection in microwave ablation: the effectiveness of 0.9 % NaCl versus 5 % dextrose in an ex vivo experimental set-up","authors":"Gonnie C.M. van Erp ,&nbsp;Pim Hendriks ,&nbsp;Sophie A. van den Hurk ,&nbsp;Hannah F. Winder ,&nbsp;Willemijn P.M. Scholtes ,&nbsp;Lara B.E.M. De Bats ,&nbsp;Jouke Dijkstra ,&nbsp;Mark C. Burgmans","doi":"10.1016/j.redii.2025.100060","DOIUrl":"10.1016/j.redii.2025.100060","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the effectiveness of hydrodissection using 0.9 % NaCl (saline) or 5 % dextrose in water during microwave ablation at different hydrodissection fluid thicknesses, in an ex vivo experimental set-up.</div></div><div><h3>Methods</h3><div>Two porcine liver parts were placed in a plastic container simulating a superficial liver ablation with adjacent tissue. The space between the livers was filled with either saline or 5 % dextrose in water. Microwave ablation was performed 4 min at 100 W, at 15 mm from the liver surface. Three thermocouples were used to determine the heat propagation: (1) between the microwave ablation antenna and liver surface; (2) 5 mm from the surface of the adjacent tissue; (3) 15 mm from the surface of the adjacent tissue. Forty experiments were performed using hydrodissection fluid thicknesses ranging from 1 to 10 mm. The maximum temperature increase for each thermocouple was determined. A Spearman’s correlation analysis assessed the relationship between the hydrodissection fluid thickness (in millimeters) and the temperature increase (in degrees Celsius) per fluid.</div></div><div><h3>Results</h3><div>At 5 mm within the adjacent tissue, use of 1 mm hydrodissection fluid thickness with 5 % dextrose in water resulted in less temperature increase (4.6 °C) compared to saline (6.8 °C). Additionally, at this distance, a negative correlation was observed between hydrodissection fluid thickness and temperature increase for both saline hydrodissection (<em>r</em>(18) = −0.96, <em>p</em> &lt; 0.001) and 5 % dextrose in water hydrodissection (<em>r</em>(18) = -0.81, <em>p</em> &lt; 0.001), which differs significantly (<em>p</em> = 0.011).</div></div><div><h3>Conclusion</h3><div>Results from this experimental ex vivo study suggest that 5 % dextrose in water may protect adjacent critical structures better from heating during microwave ablation than saline.</div></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"14 ","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144098659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing active teaching to hybrid lecture-based method for learning radiology basics: A single center controlled study 放射学基础知识的主动教学与混合授课方法之比较:单中心对照研究
Pub Date : 2025-03-01 DOI: 10.1016/j.redii.2025.100054
Fabien de Oliveira , Jean-Paul Beregi , Hugo Potier , Thorgal Brun , Chris Serrand , Julien Frandon

Objective

There is a lack of knowledge about radiology among medical students at the start of their curriculum. The optimal teaching method for radiological basics remains uncertain. We conducted a controlled trial to compare the effectiveness of full active learning and hybrid lecture-based teaching methods.

Methods

All second-year medical students at Nîmes University Hospital (Nîmes, France) were invited to participate in a training session in the radiology unit. Volunteers were divided into hybrid lecture-based and full active learning groups. The hybrid lecture-based group received a lecture-based session followed by a unit visit, while the full active learning group utilized a structured form with progressive objectives during the visit. Pretests, immediate post-tests, and two-week follow-up tests were conducted. Short-term progression was the primary outcome, with secondary objectives including mid-term acquisition and associated factors.

Results

51 students participated, with 20 in the hybrid lecture-based group and 31 in the full active learning group. Both groups exhibited significant progression between the first and second tests (+8.48 and +2.52 respectively, p < 0.01). The hybrid lecture-based group showed significantly greater mean progression (p < 0.01). Mid-term results indicated score decrease particularly in the hybrid lecture-based group, but it still maintained significantly superior performance (15.02/20 versus 12.33/20 for full active learning group, p < 0.01).

Conclusion

The hybrid pedagogical method yielded superior results in teaching second-year medical students the basics of radiology compared to the full active learning teaching method.
目的医学生在课程开始时对放射学知识缺乏了解。放射学基础知识的最佳教学方法仍不确定。我们进行了一项对照试验,以比较完全主动学习和混合授课教学方法的有效性。方法邀请法国 mes大学医院(n mes, France)所有二年级医学生参加放射科培训。志愿者被分为混合型讲座组和完全主动学习组。混合型以讲座为基础的小组接受了以讲座为基础的课程,然后进行了单元访问,而完全主动学习组在访问期间使用了具有渐进目标的结构化形式。进行了预测试、即时后测试和两周的随访测试。短期进展是主要结果,次要目标包括中期习得和相关因素。结果51名学生参与,其中20人在混合式授课组,31人在完全主动学习组。两组在第一次和第二次测试之间均表现出显著进展(分别为+8.48和+2.52,p <;0.01)。混合授课组的平均进展显著提高(p <;0.01)。中期结果显示混合型授课组得分下降尤其明显,但仍保持显著优势(15.02/20 vs 12.33/20);0.01)。结论混合教学法对二年级医学生放射学基础知识的教学效果优于全主动学习教学法。
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引用次数: 0
Possible limited justification for systematic head computed tomography scans based solely on antithrombotic therapy in elderly patients (aged 75 or older) with mild traumatic brain injury 对轻度外伤性脑损伤的老年患者(75岁或以上)进行系统的头部计算机断层扫描仅基于抗血栓治疗的可能有限的理由。
Pub Date : 2025-01-16 DOI: 10.1016/j.redii.2024.100053
Emma Jaffres , Jean-Nicolas Dacher , Mehdi Taalba , Frédéric Roca , Matthieu Garnier , Sébastien Normant , Mathieu Lozouet , Emmanuel Gérardin , Julien Burel

Rationale and objectives

Recent literature suggests that performing systematic head computed tomography (CT) scans for mild traumatic brain injury (mTBI) in patients undergoing antithrombotic therapy offers limited benefits. This study aims to evaluate a set of criteria that could potentially eliminate the need for systematic head CT scans, performed solely because of the antithrombotic treatment status, in elderly patients (aged 75 or older) presenting with mTBI.

Materials and methods

All patients aged 75 or older who underwent a head CT scan at our academic center for mTBI while on antithrombotic therapy between January and December 2022 were retrospectively included in this study. Patients were categorized into two groups. The first group, referred to as the “At-risk group”, included patients with any of the following: GCS score < 15 or cognitive impairment; initial loss of consciousness; hemodynamic instability; signs of fractures; extensive subcutaneous hematoma; severe or treatment-resistant headache; vomiting; seizure; any neurological deficit; intoxication; amnesia; or a history of neurosurgery. The second group, referred to as the “Not-at-risk group”, comprised patients without any of these criteria.

Results

A total of 1415 patients were included. Post-traumatic intracranial hemorrhage (P < 0.001), brain herniation (P = 0.003), and fractures (P < 0.001) occurred statistically more frequently in the At-risk group. Six post-traumatic hemorrhagic brain injuries were found in the Not-at-risk group, that did not present any of the studied criteria, and all these injuries were minor (localized SAH; millimetric SDH). Furthermore, none of these required immediate or delayed surgical intervention, and no neurological deterioration or deaths occurred in these patients.

Conclusion

In conclusion, conducting systematic head CT scans based solely on antithrombotic therapy in elderly patients aged 75 or older with mTBI might be irrelevant.
理由和目的:最近的文献表明,对接受抗血栓治疗的轻度创伤性脑损伤(mTBI)患者进行系统的头部计算机断层扫描(CT)扫描的益处有限。本研究旨在评估一套标准,这些标准有可能消除仅因抗血栓治疗状态而进行系统头部CT扫描的必要性,适用于老年mTBI患者(75岁或以上)。材料和方法:所有在2022年1月至12月期间在我们的学术中心接受抗血栓治疗期间接受mTBI头部CT扫描的75岁及以上患者回顾性纳入本研究。患者分为两组。第一组被称为“高危组”,包括以下任何一种情况的患者:GCS评分< 15或认知障碍;最初的意识丧失;血流动力学不稳定;骨折的迹象;大面积皮下血肿;严重头痛或治疗难治性头痛;呕吐;癫痫发作;任何神经缺陷;中毒;遗忘;或者有神经外科病史。第二组被称为“无风险组”,由没有上述任何标准的患者组成。结果:共纳入1415例患者。创伤后颅内出血(P < 0.001)、脑疝(P = 0.003)和骨折(P < 0.001)在高危组发生率更高。在非高危组中发现了6例创伤后出血性脑损伤,没有出现任何研究标准,所有这些损伤都是轻微的(局部SAH;名为“SDH)。此外,这些患者都不需要立即或延迟手术干预,也没有发生神经功能恶化或死亡。结论:在75岁及以上高龄mTBI患者中,仅基于抗栓治疗进行系统的头部CT扫描可能无关紧要。
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引用次数: 0
Dedicated software to harmonize the follow-up of oncological patients 协调肿瘤患者随访的专用软件
Pub Date : 2024-09-24 DOI: 10.1016/j.redii.2024.100051
Mathias Illy , Axel Bartoli , Julien Mancini , Florence Duffaud , Vincent Vidal , Farouk Tradi

Objective

To test and evaluate a sofware dedicated to the follow-up of oncological CT scans for potential use in the Radiology department.

Materials and methods

In this retrospective study, 37 oncological patients with baseline and follow-up CT scans were reinterpreted using a dedicated software. Baseline CT scans were chosen from the imaging reports available in our PACS (picture archiving and communicatin systems). Follow-up interpretations were independently assessed with the software. We evaluated the target lesion sums and the tumor response based on RECIST 1.1 (Response Evaluation Criteria in Solid Tumors).

Results

There was no significant difference in the target lesion sums and the tumor response assessments between the PACS data and the imaging software. There was no over or underestimation of the disease with the software. There was a sigificant deviation (progression versus stability) in three cases. For two patients, this difference was related to the evaluation of the response of non-target lesions. The difference in the third patient was due to comparison with a previous CT scan than to the baseline exam. There was a miscalculation in 13 % of the reports and in 28 % of the cases the examination was compared to the previous CT scan. Finally, the tumor response was not detailed in 43 % of the follow-up reports.

Conclusion

The use of dedicated oncology monitoring software could help in reducing intepretation time and in limiting human errors.
材料和方法在这项回顾性研究中,使用专用软件对 37 名肿瘤患者的基线和随访 CT 扫描进行了重新解读。基线 CT 扫描是从我们的 PACS(图片存档和通信系统)中的成像报告中选择的。随访解读由软件独立评估。我们根据 RECIST 1.1(实体瘤反应评估标准)对靶病灶总和和肿瘤反应进行了评估。结果 PACS 数据和成像软件在靶病灶总和和肿瘤反应评估方面没有显著差异。软件没有高估或低估病情。有三个病例存在明显偏差(进展与稳定)。其中两名患者的差异与非目标病变的反应评估有关。第三位患者的差异是由于与之前的 CT 扫描对比而非基线检查造成的。有 13% 的报告存在计算错误,28% 的病例是将检查结果与之前的 CT 扫描结果进行比较。最后,43% 的随访报告没有详细说明肿瘤反应。
{"title":"Dedicated software to harmonize the follow-up of oncological patients","authors":"Mathias Illy ,&nbsp;Axel Bartoli ,&nbsp;Julien Mancini ,&nbsp;Florence Duffaud ,&nbsp;Vincent Vidal ,&nbsp;Farouk Tradi","doi":"10.1016/j.redii.2024.100051","DOIUrl":"10.1016/j.redii.2024.100051","url":null,"abstract":"<div><h3>Objective</h3><div>To test and evaluate a sofware dedicated to the follow-up of oncological CT scans for potential use in the Radiology department.</div></div><div><h3>Materials and methods</h3><div>In this retrospective study, 37 oncological patients with baseline and follow-up CT scans were reinterpreted using a dedicated software. Baseline CT scans were chosen from the imaging reports available in our PACS (picture archiving and communicatin systems). Follow-up interpretations were independently assessed with the software. We evaluated the target lesion sums and the tumor response based on RECIST 1.1 (Response Evaluation Criteria in Solid Tumors).</div></div><div><h3>Results</h3><div>There was no significant difference in the target lesion sums and the tumor response assessments between the PACS data and the imaging software. There was no over or underestimation of the disease with the software. There was a sigificant deviation (progression versus stability) in three cases. For two patients, this difference was related to the evaluation of the response of non-target lesions. The difference in the third patient was due to comparison with a previous CT scan than to the baseline exam. There was a miscalculation in 13 % of the reports and in 28 % of the cases the examination was compared to the previous CT scan. Finally, the tumor response was not detailed in 43 % of the follow-up reports.</div></div><div><h3>Conclusion</h3><div>The use of dedicated oncology monitoring software could help in reducing intepretation time and in limiting human errors.</div></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"12 ","pages":"Article 100051"},"PeriodicalIF":0.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000127/pdfft?md5=959609feb9ca301b923eaa1ed37b79e9&pid=1-s2.0-S2772652524000127-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glenoid morphology variation between patients with hypermobile shoulder joints and controls: Identification of hyperlaxity-related morphologic bone changes 肩关节活动过度患者与对照组之间的盂状关节形态变化:识别与过度松弛相关的骨形态变化
Pub Date : 2024-08-23 DOI: 10.1016/j.redii.2024.100052
Sirine Hamitouche , Fatma Boubaker , Gabriela Hossu , François Sirveaux , Romain Gillet , Alain Blum , Pedro Augusto Gondim Teixeira

Objective

Our study aims to quantitatively determine the concavity of the glenoid articular surface in patients with hypermobile shoulders compared to those without.

Method

We examined medical records of shoulder CTs from 2017 to 2022, selecting 50 patients with clinical signs of joint hypermobility for our case group and 54 for our control group. Two blinded readers independently assessed the glenoid morphology, calculating the glenoid concavity angle (GCA) and evaluating the articular surface shape as concave, flat, or convex. They also recorded the presence and severity of glenoid dysplasia. We compared these assessments between groups.

Results

The mean GCA was significantly lower in the hypermobile group (2.3 ± 3.7° and 2.3 ± 3.8°) versus controls (6.6 ± 3.3° and 5.3 ± 3.8°) (P < 0.05). Interobserver reproducibility was high (ICC=0.76). A stark difference in glenoid morphology was noted between groups (P < 0.001), with a majority of hypermobile patients having a flat or convex glenoid. GCAs decreased with increasing shoulder laxity and dysplasia. GCA showed 77–81 % sensitivity and 55–82 % specificity for detecting shoulder hyperlaxity with a 4° cutoff.

Conclusion

There is a significant association between GCA and shoulder hyperlaxity, demonstrating diagnostic efficacy and substantial interobserver agreement.

Clinical Relevance

GCA values lower than 4° warrant further clinical investigation for shoulder hyperlaxity and associated conditions, which is crucial for patient treatment planning.

目的我们的研究旨在定量测定肩关节活动过度患者与非肩关节活动过度患者的盂关节面凹陷程度。方法我们检查了2017年至2022年的肩关节CT病历,选择50例有关节活动过度临床表现的患者为病例组,54例为对照组。两名盲人阅读者独立评估盂形态,计算盂凹角(GCA)并将关节面形状评估为凹、平或凸。他们还记录了髋臼发育不良的存在和严重程度。结果活动过度组的平均 GCA(2.3 ± 3.7°和 2.3 ± 3.8°)明显低于对照组(6.6 ± 3.3°和 5.3 ± 3.8°)(P <0.05)。观察者之间的重复性很高(ICC=0.76)。各组之间的盂形体形态差异明显(P <0.001),大多数活动过度患者的盂形体为扁平或凸形。随着肩关节松弛和发育不良程度的增加,GCAs 也随之降低。结论GCA与肩关节过度松弛之间存在显著关联,显示出诊断效果和观察者之间的高度一致。临床意义GCA值低于4°时,临床上应进一步检查肩关节过度松弛及相关疾病,这对患者的治疗计划至关重要。
{"title":"Glenoid morphology variation between patients with hypermobile shoulder joints and controls: Identification of hyperlaxity-related morphologic bone changes","authors":"Sirine Hamitouche ,&nbsp;Fatma Boubaker ,&nbsp;Gabriela Hossu ,&nbsp;François Sirveaux ,&nbsp;Romain Gillet ,&nbsp;Alain Blum ,&nbsp;Pedro Augusto Gondim Teixeira","doi":"10.1016/j.redii.2024.100052","DOIUrl":"10.1016/j.redii.2024.100052","url":null,"abstract":"<div><h3>Objective</h3><p>Our study aims to quantitatively determine the concavity of the glenoid articular surface in patients with hypermobile shoulders compared to those without.</p></div><div><h3>Method</h3><p>We examined medical records of shoulder CTs from 2017 to 2022, selecting 50 patients with clinical signs of joint hypermobility for our case group and 54 for our control group. Two blinded readers independently assessed the glenoid morphology, calculating the glenoid concavity angle (GCA) and evaluating the articular surface shape as concave, flat, or convex. They also recorded the presence and severity of glenoid dysplasia. We compared these assessments between groups.</p></div><div><h3>Results</h3><p>The mean GCA was significantly lower in the hypermobile group (2.3 ± 3.7° and 2.3 ± 3.8°) versus controls (6.6 ± 3.3° and 5.3 ± 3.8°) (<em>P</em> &lt; 0.05). Interobserver reproducibility was high (ICC=0.76). A stark difference in glenoid morphology was noted between groups (<em>P</em> &lt; 0.001), with a majority of hypermobile patients having a flat or convex glenoid. GCAs decreased with increasing shoulder laxity and dysplasia. GCA showed 77–81 % sensitivity and 55–82 % specificity for detecting shoulder hyperlaxity with a 4° cutoff.</p></div><div><h3>Conclusion</h3><p>There is a significant association between GCA and shoulder hyperlaxity, demonstrating diagnostic efficacy and substantial interobserver agreement.</p></div><div><h3>Clinical Relevance</h3><p>GCA values lower than 4° warrant further clinical investigation for shoulder hyperlaxity and associated conditions, which is crucial for patient treatment planning.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"11 ","pages":"Article 100052"},"PeriodicalIF":0.0,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000139/pdfft?md5=c3bfd72b86aa1ece4b9aab19ebbbae67&pid=1-s2.0-S2772652524000139-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Research in diagnostic and interventional imaging
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