Pub Date : 2024-09-01Epub Date: 2024-06-11DOI: 10.1016/j.redii.2024.100050
Clément Ravenel , Charlotte Martin-Peltier , Maxime Lacroix , Fadila Mihoubi-Bouvier , Christelle Nguyen , Romain Touzé , Jean-Luc Drapé
Background
Traditionally, transforaminal steroid injection is performed in the management of cervical radiculopathy in medical failure treatment but carried a true risk of catastrophic complication. Another approach currently used is to perform intra-articular facet steroid injection to reach the epidural space.
Purpose
The aim of this study was to describe the evolution of symptoms following intra-articular facet steroid injection in cervical radiculopathy.
Material and methods
We conducted a retrospective study. We assessed all patients who had a CT-guided intra-articular facet steroid injection in our center (xx, xx, xx) from December 2015 to February 2021. Cervical MR pretherapeutic images were analyzed and classified according to cervical pain etiology: uncodiscarthrosis, disk herniation or congestive cervical posterior osteo-arthritis. All patients had clinical initial evaluation and then follow-up at 1 and 6 months. Pain severity was rated on a visual analog scale and expressed as a percentage of improvement.
Results
Ninety-three patients were included. There were 56 patients with uncodiscarthrosis, 29 with a disk herniation and 8 with a cervical posterior congestive osteoarthritis. A significant improvement of the visual analog scale percentage was found for all patient at 1 and 6 months (p < 0.01). Visual analog scale percentage improvement was about 50 % for all etiologies. For all patients, no severe complications were reported.
Conclusion
Intra-articular facet steroid injection may be considered for the treatment of cervical radiculopathy when other medical treatments have failed.
{"title":"Efficacity of CT-guided intra-articular cervical facet steroid injection for cervical radiculopathy","authors":"Clément Ravenel , Charlotte Martin-Peltier , Maxime Lacroix , Fadila Mihoubi-Bouvier , Christelle Nguyen , Romain Touzé , Jean-Luc Drapé","doi":"10.1016/j.redii.2024.100050","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100050","url":null,"abstract":"<div><h3>Background</h3><p>Traditionally, transforaminal steroid injection is performed in the management of cervical radiculopathy in medical failure treatment but carried a true risk of catastrophic complication. Another approach currently used is to perform intra-articular facet steroid injection to reach the epidural space.</p></div><div><h3>Purpose</h3><p>The aim of this study was to describe the evolution of symptoms following intra-articular facet steroid injection in cervical radiculopathy.</p></div><div><h3>Material and methods</h3><p>We conducted a retrospective study. We assessed all patients who had a CT-guided intra-articular facet steroid injection in our center (xx, xx, xx) from December 2015 to February 2021. Cervical MR pretherapeutic images were analyzed and classified according to cervical pain etiology: uncodiscarthrosis, disk herniation or congestive cervical posterior osteo-arthritis. All patients had clinical initial evaluation and then follow-up at 1 and 6 months. Pain severity was rated on a visual analog scale and expressed as a percentage of improvement.</p></div><div><h3>Results</h3><p>Ninety-three patients were included. There were 56 patients with uncodiscarthrosis, 29 with a disk herniation and 8 with a cervical posterior congestive osteoarthritis. A significant improvement of the visual analog scale percentage was found for all patient at 1 and 6 months (<em>p</em> < 0.01). Visual analog scale percentage improvement was about 50 % for all etiologies. For all patients, no severe complications were reported.</p></div><div><h3>Conclusion</h3><p>Intra-articular facet steroid injection may be considered for the treatment of cervical radiculopathy when other medical treatments have failed.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"11 ","pages":"Article 100050"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000115/pdfft?md5=8c62587e414d0e3f2916972c13a44253&pid=1-s2.0-S2772652524000115-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To assess the efficacy of the gelatin torpedoes embolization technique after lung neoplastic lesions percutaneous radiofrequency ablation (PRFA) to reduce chest tube placement rate and hospital length of stay, and the safety of this embolization technique.
Materials and methods
A total of 114 PRFA of lung neoplastic lesions performed in two centers between January 2017 and December 2022 were retrospectively reviewed. Two groups were compared, with 42 PRFA with gelatin torpedoes embolization technique (gelatin group) and 72 procedures without (control group). Procedures were performed by one of seven interventional radiologists using LeVeen CoAccess™ probe. Multivariate analyses were performed to identify risk factors for chest tube placement and hospital length of stay.
Results
There was a significantly lower chest tube placement rate in the gelatin group compared to the control group (3 [7.1 %] vs. 27 [37.5 %], p < 0,001). Multivariate analysis showed a significant association between chest tube placement and gelatin torpedoes embolization technique (OR: 0.09; 95 % CI: 0.02–0.32; p = 0.0006). No significant difference was found in hospital length of stay between the two groups. Multivariate analysis did not show a significant relationship between hospital length of stay and gelatin torpedoes embolization technique. No embolic complication occurred in the gelatin group.
Conclusion
Gelatin torpedoes embolization technique after PRFA of lung neoplastic lesions resulted in significantly reduced chest tube placement rate in our patient population. No significant reduction in hospital length of stay was observed. No major complication occurred in the gelatin group.
{"title":"Chest tube placement incidence when using gelatin sponge torpedoes after pulmonary radiofrequency ablation","authors":"Pauline Graveleau , Éric Frampas , Christophe Perret , Stéphanie Volpi , François-Xavier Blanc , Thomas Goronflot , Renan Liberge","doi":"10.1016/j.redii.2024.100047","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100047","url":null,"abstract":"<div><h3>Purpose</h3><p>To assess the efficacy of the gelatin torpedoes embolization technique after lung neoplastic lesions percutaneous radiofrequency ablation (PRFA) to reduce chest tube placement rate and hospital length of stay, and the safety of this embolization technique.</p></div><div><h3>Materials and methods</h3><p>A total of 114 PRFA of lung neoplastic lesions performed in two centers between January 2017 and December 2022 were retrospectively reviewed. Two groups were compared, with 42 PRFA with gelatin torpedoes embolization technique (gelatin group) and 72 procedures without (control group). Procedures were performed by one of seven interventional radiologists using LeVeen CoAccess™ probe. Multivariate analyses were performed to identify risk factors for chest tube placement and hospital length of stay.</p></div><div><h3>Results</h3><p>There was a significantly lower chest tube placement rate in the gelatin group compared to the control group (3 [7.1 %] vs. 27 [37.5 %], <em>p</em> < 0,001). Multivariate analysis showed a significant association between chest tube placement and gelatin torpedoes embolization technique (OR: 0.09; 95 % CI: 0.02–0.32; <em>p</em> = 0.0006). No significant difference was found in hospital length of stay between the two groups. Multivariate analysis did not show a significant relationship between hospital length of stay and gelatin torpedoes embolization technique. No embolic complication occurred in the gelatin group.</p></div><div><h3>Conclusion</h3><p>Gelatin torpedoes embolization technique after PRFA of lung neoplastic lesions resulted in significantly reduced chest tube placement rate in our patient population. No significant reduction in hospital length of stay was observed. No major complication occurred in the gelatin group.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"10 ","pages":"Article 100047"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000085/pdfft?md5=725b1046861ea7f764a7a3b33aab91c1&pid=1-s2.0-S2772652524000085-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140644325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-04-24DOI: 10.1016/j.redii.2024.100045
Annie-Lyne Petit , Rabih Alwan , Julien Behr , Paul Calame , Marion Lenoir , Hubert Ducou le Pointe , Éric Delabrousse
Background
Abdominal radiographs remain useful in newborns. Given the high radiation sensitivity of this population, it is necessary to optimize acquisition techniques to minimize radiation exposure.
Objective
Evaluate the effects of three additional filtrations on radiation dose and image quality in abdominal X-rays of newborns using an anthropomorphic phantom.
Material and method
Abdominal radiographs of an anthropomorphic newborn phantom were performed using acquisition parameters ranging from 55 to 70 kV and from 0.4 to 2.5 mAs, without and with three different additional filtrations: 0.1 mm copper (Cu) + 1 mm aluminum (Al), 0.2 mm copper + 1 mm aluminum, and 2 mm aluminum. For each X-ray the dose area product (DAP) was measured, the signal-to-noise ratio (SNR) was calculated, and image quality (IQ) was evaluated by two blinded radiologists using the absolute visual grading analysis (VGA) method.
Results
Adding an additional filtration resulted in a significant reduction in DAP, with a decrease of 42% using 2 mm Al filtration, 65% with 0.1 mm Cu + 1 mm Al filtration, and 78% with 0.2 mm Cu + 1 mm Al filtration (p < 0.01). The addition of 2 mm aluminum filtration does not significantly decrease the SNR (p = 0.31), CNR (p = 0.52) or the IQ (p = 0.12 and 0.401 for reader 1 and 2, respectively). However, adding copper-containing filtration leads to a significant decrease in, SNR, CNR and IQ.
Conclusion
Adding a 2 mm Al additional filtration for abdominal radiographs in newborns can significantly reduce the radiation dose without causing a significant decrease in image quality.
{"title":"Dose optimization in newborn abdominal radiography: Assessing the added value of additional filtration on radiation dose and image quality using an anthropomorphic phantom","authors":"Annie-Lyne Petit , Rabih Alwan , Julien Behr , Paul Calame , Marion Lenoir , Hubert Ducou le Pointe , Éric Delabrousse","doi":"10.1016/j.redii.2024.100045","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100045","url":null,"abstract":"<div><h3>Background</h3><p>Abdominal radiographs remain useful in newborns. Given the high radiation sensitivity of this population, it is necessary to optimize acquisition techniques to minimize radiation exposure.</p></div><div><h3>Objective</h3><p>Evaluate the effects of three additional filtrations on radiation dose and image quality in abdominal X-rays of newborns using an anthropomorphic phantom.</p></div><div><h3>Material and method</h3><p>Abdominal radiographs of an anthropomorphic newborn phantom were performed using acquisition parameters ranging from 55 to 70 kV and from 0.4 to 2.5 mAs, without and with three different additional filtrations: 0.1 mm copper (Cu) + 1 mm aluminum (Al), 0.2 mm copper + 1 mm aluminum, and 2 mm aluminum. For each X-ray the dose area product (DAP) was measured, the signal-to-noise ratio (SNR) was calculated, and image quality (IQ) was evaluated by two blinded radiologists using the absolute visual grading analysis (VGA) method.</p></div><div><h3>Results</h3><p>Adding an additional filtration resulted in a significant reduction in DAP, with a decrease of 42% using 2 mm Al filtration, 65% with 0.1 mm Cu + 1 mm Al filtration, and 78% with 0.2 mm Cu + 1 mm Al filtration (<em>p</em> < 0.01). The addition of 2 mm aluminum filtration does not significantly decrease the SNR (<em>p</em> = 0.31), CNR (<em>p</em> = 0.52) or the IQ (<em>p</em> = 0.12 and 0.401 for reader 1 and 2, respectively). However, adding copper-containing filtration leads to a significant decrease in, SNR, CNR and IQ.</p></div><div><h3>Conclusion</h3><p>Adding a 2 mm Al additional filtration for abdominal radiographs in newborns can significantly reduce the radiation dose without causing a significant decrease in image quality.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"10 ","pages":"Article 100045"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000061/pdfft?md5=74dae0f6a82cde59ddb22e12c46456d8&pid=1-s2.0-S2772652524000061-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Non-invasive subtyping of hepatocellular adenomas (HCA) remains challenging for several subtypes, thus carrying different levels of risks and management. The goal of this study is to devise a multivariable diagnostic model based on basic clinical features (age and sex) combined with MRI-radiomics and to evaluate its diagnostic performance.
Methods
This single-center retrospective case-control study included all consecutive patients with HCA identified within the pathological database from our institution from January 2003 to April 2018 with MRI examination (T2, T1-no injection/injection-arterial-portal); volumes of interest were manually delineated in adenomas and 38 textural features were extracted (LIFEx, v5.10). Qualitative (i.e., visual on MRI) and automatic (computer-assisted) analysis were compared. The prognostic scores of a multivariable diagnostic model based on basic clinical features (age and sex) combined with MRI-radiomics (tumor volume and texture features) were assessed using a cross-validated Random Forest algorithm.
Results
Via visual MR-analysis, HCA subgroups could be classified with balanced accuracies of 80.8 % (I-HCA or ß-I-HCA, the two being indistinguishable), 81.8 % (H-HCA) and 74.4 % (sh-HCA or ß-HCA also indistinguishable). Using a model including age, sex, volume and texture variables, HCA subgroups were predicted (multivariate classification) with an averaged balanced accuracy of 58.6 %, best=73.8 % (sh-HCA) and 71.9 % (ß-HCA). I-HCA and ß-I-HCA could be also distinguished (binary classification) with a balanced accuracy of 73 %.
Conclusion
Multiple HCA subtyping could be improved using machine-learning algorithms including two clinical features, i.e., age and sex, combined with MRI-radiomics. Future HCA studies enrolling more patients will further test the validity of the model.
{"title":"Assessment of a multivariable model using MRI-radiomics, age and sex for the classification of hepatocellular adenoma subtypes","authors":"Guillaume Declaux , Baudouin Denis de Senneville , Hervé Trillaud , Paulette Bioulac-Sage , Charles Balabaud , Jean-Frédéric Blanc , Laurent Facq , Nora Frulio","doi":"10.1016/j.redii.2024.100046","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100046","url":null,"abstract":"<div><h3>Objectives</h3><p>Non-invasive subtyping of hepatocellular adenomas (HCA) remains challenging for several subtypes, thus carrying different levels of risks and management. The goal of this study is to devise a multivariable diagnostic model based on basic clinical features (age and sex) combined with MRI-radiomics and to evaluate its diagnostic performance.</p></div><div><h3>Methods</h3><p>This single-center retrospective case-control study included all consecutive patients with HCA identified within the pathological database from our institution from January 2003 to April 2018 with MRI examination (T2, T1-no injection/injection-arterial-portal); volumes of interest were manually delineated in adenomas and 38 textural features were extracted (LIFEx, v5.10). Qualitative (i.e., visual on MRI) and automatic (computer-assisted) analysis were compared. The prognostic scores of a multivariable diagnostic model based on basic clinical features (age and sex) combined with MRI-radiomics (tumor volume and texture features) were assessed using a cross-validated Random Forest algorithm.</p></div><div><h3>Results</h3><p>Via visual MR-analysis, HCA subgroups could be classified with balanced accuracies of 80.8 % (I-HCA or ß-I-HCA, the two being indistinguishable), 81.8 % (H-HCA) and 74.4 % (sh-HCA or ß-HCA also indistinguishable). Using a model including age, sex, volume and texture variables, HCA subgroups were predicted (multivariate classification) with an averaged balanced accuracy of 58.6 %, best=73.8 % (sh-HCA) and 71.9 % (ß-HCA). I-HCA and ß-I-HCA could be also distinguished (binary classification) with a balanced accuracy of 73 %.</p></div><div><h3>Conclusion</h3><p>Multiple HCA subtyping could be improved using machine-learning algorithms including two clinical features, i.e., age and sex, combined with MRI-radiomics. Future HCA studies enrolling more patients will further test the validity of the model.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"10 ","pages":"Article 100046"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000073/pdfft?md5=94bef060382e3f1b831777f568634901&pid=1-s2.0-S2772652524000073-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140348091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-04-26DOI: 10.1016/j.redii.2024.100048
Youssef Zaarour , Haytham Derbel , Charles Tran , Laetitia Saccentia , Benjamin Longère , Maxime Blain , Giuliana Amaddeo , Alain Luciani , Hicham Kobeiter , Vania Tacher
Rationale and objectives
A new microcatheter was recently developed claiming to reduce beads reflux in drug-eluting bead transarterial chemoembolization (DEB-TACE). The aim of this study was to compare the reflux control microcatheter ability versus a standard microcatheter for TACE treatment in patients with hepatocellular carcinoma.
Material and methods
Patients were prospectively included between November 2017 and February 2022. They received a DEB-TACE treatment with charged radiopaque beads using standard microcatheters or the SeQure reflux control microcatheter (Guerbet, France) and were assigned respectively to a control and a test group. Beads distribution mismatch was evaluated between the targeted territory on treatment planning CBCT and beads’ spontaneous opacities on the post-intervention CBCT and the 1-month CT scanner.
Results
Twenty-three patients (21 men, median age 64 years [12.5 years]) with 37 hepatocellular carcinoma nodules were treated. The control group consisted of 13 patients – 19 nodules, while the test group included ten patients - 18 nodules. Non target embolization (NTE) was found in 20 % (2/10) of patients in the test group and 85 % (11/13) in the control group. NTE involved only an adjacent segment in the test group while it affected the adjacent biliary sector or even the contralateral liver lobe in the control group. No complication linked to NTE was found in the test group, while it led to one case of ischemic cholangitis and another case of biloma in the control group.
Conclusion
The reflux control microcatheter may be efficient in reducing NTE and thus eventual adverse events in comparison to standard of care end-hole microcatheters.
{"title":"Evaluation of a new beads reflux control microcatheter in drug-eluting bead transarterial chemoembolization","authors":"Youssef Zaarour , Haytham Derbel , Charles Tran , Laetitia Saccentia , Benjamin Longère , Maxime Blain , Giuliana Amaddeo , Alain Luciani , Hicham Kobeiter , Vania Tacher","doi":"10.1016/j.redii.2024.100048","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100048","url":null,"abstract":"<div><h3>Rationale and objectives</h3><p>A new microcatheter was recently developed claiming to reduce beads reflux in drug-eluting bead transarterial chemoembolization (DEB-TACE). The aim of this study was to compare the reflux control microcatheter ability versus a standard microcatheter for TACE treatment in patients with hepatocellular carcinoma.</p></div><div><h3>Material and methods</h3><p>Patients were prospectively included between November 2017 and February 2022. They received a DEB-TACE treatment with charged radiopaque beads using standard microcatheters or the SeQure reflux control microcatheter (Guerbet, France) and were assigned respectively to a control and a test group. Beads distribution mismatch was evaluated between the targeted territory on treatment planning CBCT and beads’ spontaneous opacities on the post-intervention CBCT and the 1-month CT scanner.</p></div><div><h3>Results</h3><p>Twenty-three patients (21 men, median age 64 years [12.5 years]) with 37 hepatocellular carcinoma nodules were treated. The control group consisted of 13 patients – 19 nodules, while the test group included ten patients - 18 nodules. Non target embolization (NTE) was found in 20 % (2/10) of patients in the test group and 85 % (11/13) in the control group. NTE involved only an adjacent segment in the test group while it affected the adjacent biliary sector or even the contralateral liver lobe in the control group. No complication linked to NTE was found in the test group, while it led to one case of ischemic cholangitis and another case of biloma in the control group.</p></div><div><h3>Conclusion</h3><p>The reflux control microcatheter may be efficient in reducing NTE and thus eventual adverse events in comparison to standard of care end-hole microcatheters.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"10 ","pages":"Article 100048"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000097/pdfft?md5=edeb8f240b5ccf0e9a313e6ce1bdde90&pid=1-s2.0-S2772652524000097-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140646782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2024-03-10DOI: 10.1016/j.redii.2024.100042
Lorenzo Carlo Pescatori , Athena Galletto Pregliasco , Haytham Derbel , Laetitia Saccenti , Mario Ghosn , Maxime Blain , Julia Chalayea , Alain Luciani , Sebastien Mulé , Giuliana Amaddeo , Hicham Kobeiter , Vania Tacher
Purpose
The aim of this study was to report the safety and tumor response rate of combined transarterial radioembolization (TARE) through the intrahepatic arteries and transarterial chemoembolization (TACE) through the extrahepatic feeding arteries (EHFA) in patients with hepatocellular carcinoma (HCC).
Methods
Patients with HCC, who had both intrahepatic and extrahepatic arterial supply visible on preinterventional multiphase CT and were treated between 2016 and 2021 with a combination of TACE and TARE on the same nodule, were retrospectively included. Epidemiological, clinical, biological, and radiological characteristics were recorded. Safety and tumor response were assessed at 6 months.
Results
Nine patients (8 men, median age 62 years [IQR: 54–72 years]) were included. Seven patients had previous treatments on the target nodule (TARE: 5; TACE: 2). The median longest axis (LA) of the lesion was 70 mm (IQR: 60–79 mm). Three patients had portal vein invasion (VP3). The EHFA originated from the right diaphragmatic artery (n = 6), the right adrenal artery (n = 2), and the left gastric artery (n = 1). The LA of the tumor portion treated with TACE was 47 mm (range: 35–64 mm). The ratio between the LA of the entire lesion and the LA treated with TACE was 1.44 (range: 1.27–1.7). One major complication occurred: acute on chronic liver failure. Median follow-up was 23 months (range: 16–29 months). Seven patients underwent further treatment: on the same lesion (n = 2), on newly appeared nodules (n = 2), and systemic treatment (n = 3). At 6-month follow-up, seven patients showed a local objective response. Time-to-progression was 13 (3.5–19) months.
Conclusion
The combination of TARE and extrahepatic TACE for HCC with both intrahepatic and extrahepatic arterial supplies seems feasible and safe. Further studies are needed to validate the effectiveness of these preliminary results.
{"title":"Combination of intrahepatic TARE and extrahepatic TACE to treat HCC patients with extrahepatic artery supply: A case series","authors":"Lorenzo Carlo Pescatori , Athena Galletto Pregliasco , Haytham Derbel , Laetitia Saccenti , Mario Ghosn , Maxime Blain , Julia Chalayea , Alain Luciani , Sebastien Mulé , Giuliana Amaddeo , Hicham Kobeiter , Vania Tacher","doi":"10.1016/j.redii.2024.100042","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100042","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of this study was to report the safety and tumor response rate of combined transarterial radioembolization (TARE) through the intrahepatic arteries and transarterial chemoembolization (TACE) through the extrahepatic feeding arteries (EHFA) in patients with hepatocellular carcinoma (HCC).</p></div><div><h3>Methods</h3><p>Patients with HCC, who had both intrahepatic and extrahepatic arterial supply visible on preinterventional multiphase CT and were treated between 2016 and 2021 with a combination of TACE and TARE on the same nodule, were retrospectively included. Epidemiological, clinical, biological, and radiological characteristics were recorded. Safety and tumor response were assessed at 6 months.</p></div><div><h3>Results</h3><p>Nine patients (8 men, median age 62 years [IQR: 54–72 years]) were included. Seven patients had previous treatments on the target nodule (TARE: 5; TACE: 2). The median longest axis (LA) of the lesion was 70 mm (IQR: 60–79 mm). Three patients had portal vein invasion (VP3). The EHFA originated from the right diaphragmatic artery (<em>n</em> = 6), the right adrenal artery (<em>n</em> = 2), and the left gastric artery (<em>n</em> = 1). The LA of the tumor portion treated with TACE was 47 mm (range: 35–64 mm). The ratio between the LA of the entire lesion and the LA treated with TACE was 1.44 (range: 1.27–1.7). One major complication occurred: acute on chronic liver failure. Median follow-up was 23 months (range: 16–29 months). Seven patients underwent further treatment: on the same lesion (<em>n</em> = 2), on newly appeared nodules (<em>n</em> = 2), and systemic treatment (<em>n</em> = 3). At 6-month follow-up, seven patients showed a local objective response. Time-to-progression was 13 (3.5–19) months.</p></div><div><h3>Conclusion</h3><p>The combination of TARE and extrahepatic TACE for HCC with both intrahepatic and extrahepatic arterial supplies seems feasible and safe. Further studies are needed to validate the effectiveness of these preliminary results.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"9 ","pages":"Article 100042"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000036/pdfft?md5=7ee5a08ff6fac05f8e0be16d189510e3&pid=1-s2.0-S2772652524000036-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140069118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2024-03-08DOI: 10.1016/j.redii.2024.100044
Shahriar Faghani , Rhodes G. Nicholas , Soham Patel , Francis I. Baffour , Mana Moassefi , Pouria Rouzrokh , Bardia Khosravi , Garret M. Powell , Shuai Leng , Katrina N. Glazebrook , Bradley J. Erickson , Christin A. Tiegs-Heiden
Background
Dual-energy CT (DECT) is a non-invasive way to determine the presence of monosodium urate (MSU) crystals in the workup of gout. Color-coding distinguishes MSU from calcium following material decomposition and post-processing. Most software labels MSU as green and calcium as blue. There are limitations in the current image processing methods of segmenting green-encoded pixels. Additionally, identifying green foci is tedious, and automated detection would improve workflow. This study aimed to determine the optimal deep learning (DL) algorithm for segmenting green-encoded pixels of MSU crystals on DECTs.
Methods
DECT images of positive and negative gout cases were retrospectively collected. The dataset was split into train (N = 28) and held-out test (N = 30) sets. To perform cross-validation, the train set was split into seven folds. The images were presented to two musculoskeletal radiologists, who independently identified green-encoded voxels. Two 3D Unet-based DL models, Segresnet and SwinUNETR, were trained, and the Dice similarity coefficient (DSC), sensitivity, and specificity were reported as the segmentation metrics.
Results
Segresnet showed superior performance, achieving a DSC of 0.9999 for the background pixels, 0.7868 for the green pixels, and an average DSC of 0.8934 for both types of pixels, respectively. According to the post-processed results, the Segresnet reached voxel-level sensitivity and specificity of 98.72 % and 99.98 %, respectively.
Conclusion
In this study, we compared two DL-based segmentation approaches for detecting MSU deposits in a DECT dataset. The Segresnet resulted in superior performance metrics. The developed algorithm provides a potential fast, consistent, highly sensitive and specific computer-aided diagnosis tool. Ultimately, such an algorithm could be used by radiologists to streamline DECT workflow and improve accuracy in the detection of gout.
{"title":"Development of a deep learning model for the automated detection of green pixels indicative of gout on dual energy CT scan","authors":"Shahriar Faghani , Rhodes G. Nicholas , Soham Patel , Francis I. Baffour , Mana Moassefi , Pouria Rouzrokh , Bardia Khosravi , Garret M. Powell , Shuai Leng , Katrina N. Glazebrook , Bradley J. Erickson , Christin A. Tiegs-Heiden","doi":"10.1016/j.redii.2024.100044","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100044","url":null,"abstract":"<div><h3>Background</h3><p>Dual-energy CT (DECT) is a non-invasive way to determine the presence of monosodium urate (MSU) crystals in the workup of gout. Color-coding distinguishes MSU from calcium following material decomposition and post-processing. Most software labels MSU as green and calcium as blue. There are limitations in the current image processing methods of segmenting green-encoded pixels. Additionally, identifying green foci is tedious, and automated detection would improve workflow. This study aimed to determine the optimal deep learning (DL) algorithm for segmenting green-encoded pixels of MSU crystals on DECTs.</p></div><div><h3>Methods</h3><p>DECT images of positive and negative gout cases were retrospectively collected. The dataset was split into train (<em>N</em> = 28) and held-out test (<em>N</em> = 30) sets. To perform cross-validation, the train set was split into seven folds. The images were presented to two musculoskeletal radiologists, who independently identified green-encoded voxels. Two 3D Unet-based DL models, Segresnet and SwinUNETR, were trained, and the Dice similarity coefficient (DSC), sensitivity, and specificity were reported as the segmentation metrics.</p></div><div><h3>Results</h3><p>Segresnet showed superior performance, achieving a DSC of 0.9999 for the background pixels, 0.7868 for the green pixels, and an average DSC of 0.8934 for both types of pixels, respectively. According to the post-processed results, the Segresnet reached voxel-level sensitivity and specificity of 98.72 % and 99.98 %, respectively.</p></div><div><h3>Conclusion</h3><p>In this study, we compared two DL-based segmentation approaches for detecting MSU deposits in a DECT dataset. The Segresnet resulted in superior performance metrics. The developed algorithm provides a potential fast, consistent, highly sensitive and specific computer-aided diagnosis tool. Ultimately, such an algorithm could be used by radiologists to streamline DECT workflow and improve accuracy in the detection of gout.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"9 ","pages":"Article 100044"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277265252400005X/pdfft?md5=66437ac222a529dcf1593eee24ff8ef8&pid=1-s2.0-S277265252400005X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140066843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2024-02-01DOI: 10.1016/j.redii.2023.100037
Constance Lambeaux , Franck Lapègue , Hélio Fayolle , Yannick Degboe , Hélène Chiavassa-Gandois , Hubert Basselerie , Céline Goumarre , Romain Bilger , Nicolas Sans , Marie Faruch-Bilfeld
Objective
To determine if a lumbar musculature deficiency (paravertebral – PVM – and psoas – PM – muscles) is associated with a higher prevalence of vertebral fractures in osteoporotic patients.
Methods
To constitute the fracture group, data were collected retrospectively from patients with one or more recent osteoporotic vertebral fractures between T10 and L5 such as non-injected computerized tomography (CT), dual-energy X-ray absorptiometry (DXA). A control group was made by matching the patients on age, bone mineral density measured by DXA and gender. We analyzed PM and PVM atrophy based on cross-sectional area (CSA) adjusted to the body area as well as fatty infiltration on a 3-level scale and the average muscle density in Hounsfield units (HU).
Results
One hundred seventeen patients were included in each group. The fracture group had a lower PVM CSA than the control group (2197.92 ± 460.19 versus 2335.20 ± 394.42 mm2.m−2, respectively p = 0.015), but there was no significant difference in the PM (746.92 ± 197.89 versus 731.74 ± 215.53 mm2.m−2, respectively p = 0.575). The fracture group had a higher grade of fatty infiltration than the control group (PM: 1.3 ± 0.46 versus 1.07 ± 0.25, p < 0.001; PVM: 1.93 ± 0.5 versus 1.74 ± 0.5, p = 0.003) and a lower average muscle density (PM: 26.99 ± 12.83 versus 33.91 ± 8.12 HU, p < 0.001; PVM: 3.42 ± 21.06 versus 12.94 ± 18.88 HU, p < 0.001).
Conclusion
This study shows an association between a lack of axial musculature and the occurrence of osteoporotic vertebral fractures. Preventive strengthening exercises could be proposed to osteoporotic patients.
{"title":"Lumbar muscle involvement in the occurrence of osteoporotic vertebral fracture","authors":"Constance Lambeaux , Franck Lapègue , Hélio Fayolle , Yannick Degboe , Hélène Chiavassa-Gandois , Hubert Basselerie , Céline Goumarre , Romain Bilger , Nicolas Sans , Marie Faruch-Bilfeld","doi":"10.1016/j.redii.2023.100037","DOIUrl":"https://doi.org/10.1016/j.redii.2023.100037","url":null,"abstract":"<div><h3>Objective</h3><p>To determine if a lumbar musculature deficiency (paravertebral – PVM – and psoas – PM – muscles) is associated with a higher prevalence of vertebral fractures in osteoporotic patients.</p></div><div><h3>Methods</h3><p>To constitute the fracture group, data were collected retrospectively from patients with one or more recent osteoporotic vertebral fractures between T10 and L5 such as non-injected computerized tomography (CT), dual-energy X-ray absorptiometry (DXA). A control group was made by matching the patients on age, bone mineral density measured by DXA and gender. We analyzed PM and PVM atrophy based on cross-sectional area (CSA) adjusted to the body area as well as fatty infiltration on a 3-level scale and the average muscle density in Hounsfield units (HU).</p></div><div><h3>Results</h3><p>One hundred seventeen patients were included in each group. The fracture group had a lower PVM CSA than the control group (2197.92 ± 460.19 versus 2335.20 ± 394.42 mm<sup>2</sup>.m<sup>−2</sup>, respectively <em>p</em> = 0.015), but there was no significant difference in the PM (746.92 ± 197.89 versus 731.74 ± 215.53 mm<sup>2</sup>.m<sup>−2</sup>, respectively <em>p</em> = 0.575). The fracture group had a higher grade of fatty infiltration than the control group (PM: 1.3 ± 0.46 versus 1.07 ± 0.25, <em>p <</em> 0.001; PVM: 1.93 ± 0.5 versus 1.74 ± 0.5, <em>p</em> = 0.003) and a lower average muscle density (PM: 26.99 ± 12.83 versus 33.91 ± 8.12 HU, <em>p <</em> 0.001; PVM: 3.42 ± 21.06 versus 12.94 ± 18.88 HU, <em>p <</em> 0.001).</p></div><div><h3>Conclusion</h3><p>This study shows an association between a lack of axial musculature and the occurrence of osteoporotic vertebral fractures. Preventive strengthening exercises could be proposed to osteoporotic patients.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"9 ","pages":"Article 100037"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652523000169/pdfft?md5=3976823c7b15423074ae22dbacf2c1a0&pid=1-s2.0-S2772652523000169-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139675307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2024-01-31DOI: 10.1016/j.redii.2023.100038
Kai Liu , Qing Li , Xingxing Wang , Caixia Fu , Haitao Sun , Caizhong Chen , Mengsu Zeng
Objective
The objective of this study was to evaluate the clinical feasibility of deep learning reconstruction-accelerated thin-slice single-breath-hold half-Fourier single-shot turbo spin echo imaging (HASTEDL) for detecting pancreatic lesions, in comparison with two conventional T2-weighted imaging sequences: compressed-sensing HASTE (HASTECS) and BLADE.
Methods
From March 2022 to January 2023, a total of 63 patients with suspected pancreatic-related disease underwent the HASTEDL, HASTECS, and BLADE sequences were enrolled in this retrospectively study. The acquisition time, the pancreatic lesion conspicuity (LCP), respiratory motion artifact (RMA), main pancreatic duct conspicuity (MPDC), overall image quality (OIQ), signal-to-noise ratio (SNR), and contrast-noise-ratio (CNR) of the pancreatic lesions were compared among the three sequences by two readers.
Results
The acquisition time of both HASTEDL and HASTECS was 16 s, which was significantly shorter than that of 102 s for BLADE. In terms of qualitative parameters, Reader 1 and Reader 2 assigned significantly higher scores to the LCP, RMA, MPDC, and OIQ for HASTEDL compared to HASTECS and BLADE sequences; As for the quantitative parameters, the SNR values of the pancreatic head, body, tail, and lesions, the CNR of the pancreatic lesion measured by the two readers were also significantly higher for HASTEDL than for HASTECS and BLADE sequences.
Conclusions
Compared to conventional T2WI sequences (HASTECS and BLADE), deep-learning reconstructed HASTE enables thin slice and single-breath-hold acquisition with clinical acceptable image quality for detection of pancreatic lesions.
{"title":"Feasibility of deep learning-reconstructed thin-slice single-breath-hold HASTE for detecting pancreatic lesions: A comparison with two conventional T2-weighted imaging sequences","authors":"Kai Liu , Qing Li , Xingxing Wang , Caixia Fu , Haitao Sun , Caizhong Chen , Mengsu Zeng","doi":"10.1016/j.redii.2023.100038","DOIUrl":"https://doi.org/10.1016/j.redii.2023.100038","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study was to evaluate the clinical feasibility of deep learning reconstruction-accelerated thin-slice single-breath-hold half-Fourier single-shot turbo spin echo imaging (HASTE<sub>DL</sub>) for detecting pancreatic lesions, in comparison with two conventional T2-weighted imaging sequences: compressed-sensing HASTE (HASTE<sub>CS</sub>) and BLADE.</p></div><div><h3>Methods</h3><p>From March 2022 to January 2023, a total of 63 patients with suspected pancreatic-related disease underwent the HASTE<sub>DL</sub>, HASTE<sub>CS</sub>, and BLADE sequences were enrolled in this retrospectively study. The acquisition time, the pancreatic lesion conspicuity (LC<sub>P</sub>), respiratory motion artifact (RMA), main pancreatic duct conspicuity (MPDC), overall image quality (OIQ), signal-to-noise ratio (SNR), and contrast-noise-ratio (CNR) of the pancreatic lesions were compared among the three sequences by two readers.</p></div><div><h3>Results</h3><p>The acquisition time of both HASTE<sub>DL</sub> and HASTE<sub>CS</sub> was 16 s, which was significantly shorter than that of 102 s for BLADE. In terms of qualitative parameters, Reader 1 and Reader 2 assigned significantly higher scores to the LC<sub>P</sub>, RMA, MPDC, and OIQ for HASTE<sub>DL</sub> compared to HASTE<sub>CS</sub> and BLADE sequences; As for the quantitative parameters, the SNR values of the pancreatic head, body, tail, and lesions, the CNR of the pancreatic lesion measured by the two readers were also significantly higher for HASTE<sub>DL</sub> than for HASTE<sub>CS</sub> and BLADE sequences.</p></div><div><h3>Conclusions</h3><p>Compared to conventional T2WI sequences (HASTE<sub>CS</sub> and BLADE), deep-learning reconstructed HASTE enables thin slice and single-breath-hold acquisition with clinical acceptable image quality for detection of pancreatic lesions.</p></div>","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"9 ","pages":"Article 100038"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652523000170/pdfft?md5=721bb9a7136e8ca36e5bc3782b2f206e&pid=1-s2.0-S2772652523000170-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139653698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of inspiration level on lung nodule volumetry","authors":"Arnaud Halter, Aïssam Labani, Catherine Roy, Mickaël Ohana","doi":"10.1016/j.redii.2024.100043","DOIUrl":"https://doi.org/10.1016/j.redii.2024.100043","url":null,"abstract":"","PeriodicalId":74676,"journal":{"name":"Research in diagnostic and interventional imaging","volume":"9 ","pages":"Article 100043"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772652524000048/pdfft?md5=3c5b28a086d78aa81a899ca63bcc23a5&pid=1-s2.0-S2772652524000048-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140103384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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