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Micrococcus Peritonitis Complicating Peritoneal Dialysis. 并发腹膜透析的微球菌腹膜炎
Pub Date : 2024-02-01
Martin L Li, Ankur D Shah

Peritonitis, a serious complication of peritoneal dialysis (PD), can be caused by opportunistic pathogens like Micrococcus species on rare occasions. We present a case of Micrococcus sp peritonitis in a 55-year-old female with end-stage kidney disease on continuous cycling peritoneal dialysis for one year who presented with cloudy effluent. Initial treatment against Micrococcus sp with vancomycin, gentamicin, and prophylactic oral nystatin was successful. However, one month later, the patient presented with abdominal pain and dialysate culture again grew Micrococcus sp. Treatment with vancomycin was unsuccessful in resolving culture positivity. The patient was transitioned to hemodialysis for non-medical reasons and then was later restarted on PD without further peritonitis episodes. Micrococcus sp peritonitis in PD poses treatment challenges due to limited guidelines. Intraperitoneal vancomycin is commonly used to target Micrococcus isolates although there is a high incidence of treatment failure. This case report highlights the need for continued reporting to enhance identification, prevention, and patient outcomes in Micrococcus sp peritonitis during PD.

腹膜炎是腹膜透析(PD)的一种严重并发症,在极少数情况下可由机会性病原体(如微球菌)引起。我们报告了一例微球菌腹膜炎病例,患者是一名 55 岁的女性,患有终末期肾病,已接受连续循环腹膜透析一年,并出现流出液浑浊的症状。最初使用万古霉素、庆大霉素和预防性口服硝司他丁治疗微球菌获得成功。但一个月后,患者出现腹痛,透析液培养再次发现微球菌。由于非医疗原因,患者转为血液透析,后来又重新开始进行腹膜透析,但未再发生腹膜炎。由于指南有限,腹膜透析中的微球菌腹膜炎给治疗带来了挑战。腹腔注射万古霉素通常用于治疗微球菌分离株,但治疗失败的发生率很高。本病例报告强调了继续报告的必要性,以加强腹膜透析期间微球菌腹膜炎的识别、预防和患者预后。
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引用次数: 0
Direct Visualization of Diverticular Bleed on Colonoscopy. 结肠镜直接观察憩室出血。
Pub Date : 2024-02-01
Adam Burton, Yousef Elfanagely, May Min
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引用次数: 0
An Analysis of the Number of Patients Screened, Approached and Enrolled in Randomized Controlled Trials. 随机对照试验的筛选、接触和入组患者人数分析。
Pub Date : 2024-02-01
Andrew Aultman, Kelly C Ditter, Hector Mendez-Figuero, Kathryn Anderson, Megha Gupta, Suneet P Chauhan, Stephen Wagner
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引用次数: 0
International Medical Graduates in US Orthopedic Residency Programs: A Comprehensive Analysis. 美国骨科住院医师项目中的国际医学毕业生:综合分析。
Pub Date : 2024-02-01
Mohamad Y Fares, Peter Boufadel, Mohammad Daher, Tarek Haj Shehade, Jaspal Singh, Joseph A Abboud

Background: This study aims to provide insight regarding the different qualities of international medical graduates (IMGs) involved in US orthopedic residency programs.

Methods: Orthopedic residency programs accredited by the ACGME and listed in the AMA database were screened. Data on program size and location, IMG year of training, the geographic region of IMG's medical schools, their research experiences and number of gap years were included.

Results: A total of 167(80.3%) orthopedic residency programs were included. A total of 3838 residents were identified, of which 44 (1.15%) were IMGs. The United Kingdom and Ireland had the highest number of matched IMGs with four (9.1%) each. Massachusetts was the state with the highest number of enrolled IMGs. On average, IMGs had 26.3 publications and joined US orthopedic residency 4.66 years following medical school graduation.

Conclusion: Despite the many hurdles experienced by IMGs, a decent number succeeds in matching into US orthopedic residency programs each year.

背景:本研究旨在了解参与美国骨科住院医师培训项目的国际医学毕业生(IMG)的不同素质:本研究旨在深入了解参与美国骨科住院医师培训项目的国际医学毕业生(IMGs)的不同素质:方法:筛选了经 ACGME 认证并列入 AMA 数据库的骨科住院医师培训项目。方法:筛选了经 ACGME 认证并列入美国医学会数据库的骨科住院医师培训项目,包括项目规模和地点、IMG 培训年限、IMG 医学院所在地区、研究经历和间隔年数等数据:结果:共纳入了 167 个(80.3%)骨科住院医师培训项目。结果:共有 167 个(80.3%)骨科住院医师培训项目被纳入其中,共确定了 3838 名住院医师,其中 44 名(1.15%)为 IMG。英国和爱尔兰匹配的 IMG 人数最多,各有 4 人(9.1%)。马萨诸塞州是注册 IMG 人数最多的州。平均而言,IMGs发表了26.3篇论文,并在医学院毕业后4.66年进入美国骨科住院医生队伍:尽管IMG经历了许多障碍,但每年仍有相当数量的IMG成功进入美国骨科住院医师培训项目。
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引用次数: 0
Assessing Utility of 24-Hour Ambulatory Blood Pressure Monitoring to Distinguish Pediatric Populations Presenting with Elevated Blood Pressure in Rhode Island. 评估 24 小时非卧床血压监测对区分罗德岛州出现血压升高的儿科人群的实用性。
Pub Date : 2024-02-01
Jason Kurland, Marie Carillo, Francisco J Cordero, Robin Kremsdorf, M Khurram Faizan

This retrospective study aimed to assess the value of 24-hour ambulatory blood pressure monitoring (ABPM) in distinguishing primary from secondary hypertension in pediatric patients. Our study was conducted on 293 patients referred to a pediatric nephrology clinic over 11 years. Various ABPM parameters were analyzed, including daytime and nighttime systolic and diastolic blood pressures, heart rate, and blood pressure load. Among the participants, 74% were normotensive (white-coat hypertension), 21.5% had primary hypertension, and 4.4% had secondary hypertension. There were no significant differences in the analyzed variables between primary and secondary hypertension groups. Our findings suggest that ABPM might not reliably differentiate between the two in this cohort. As white-coat hypertension becomes more prevalent, ABPM remains a valuable tool in preventing unnecessary workups in children without sustained hypertension. However, our study did not identify specific endpoints for distinguishing primary from secondary hypertension.

这项回顾性研究旨在评估 24 小时动态血压监测 (ABPM) 在区分儿科原发性和继发性高血压方面的价值。我们的研究对象是 11 年来转诊到儿科肾病诊所的 293 名患者。我们分析了 ABPM 的各种参数,包括日间和夜间收缩压和舒张压、心率和血压负荷。参与者中,74%血压正常(白大衣高血压),21.5%患有原发性高血压,4.4%患有继发性高血压。原发性高血压组和继发性高血压组之间的分析变量无明显差异。我们的研究结果表明,ABPM 可能无法可靠地区分原发性和继发性高血压。随着白大衣高血压越来越普遍,ABPM 仍是防止无持续高血压儿童进行不必要检查的重要工具。不过,我们的研究并未确定区分原发性和继发性高血压的特定终点。
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引用次数: 0
Emergency Department Visit for Fever and Rash: DRESS Syndrome. 发热和皮疹急诊就诊:DRESS 综合征。
Pub Date : 2024-02-01
Jeffrey R Savarino, Melanie J Lippmann
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引用次数: 0
Impact of Cancer on Nutrition in the Geriatric Cancer Population. 癌症对老年癌症患者营养的影响。
Pub Date : 2024-02-01
Kanwal Bains, Ponnandai S Somasundar, Joanna Abi Chebl, Lidia A Vognar

Malnutrition in geriatric cancer patients is a leading cause of morbidity and mortality. A nutrition risk assessment should be done early to identify and treat those at risk for cancer-related malnutrition. The goal of this study was to assess nutritional status in geriatric patients diagnosed with all cause cancer. We conducted a single institutional prospective cohort study of geriatric patients with cancer from 2013-2018. Patients 65 years old and above had undergone a comprehensive geriatric assessment before starting treatment (day 0), post-treatment (day 30), and post-post treatment (day 90). Body Mass Index (BMI) and the Mini Nutritional Assessment (MNA) were used to assess nutrition status. Results showed an increase in nutrition status from pretreatment (day = 0) to treatment (day =30), followed by a decrease in MNA scores at day 90. Results showed a decrease in BMI across all time points. This study supports that cancer and anti-cancer therapy in geriatric patients cause malnutrition, indicating the importance of early nutritional evaluation and intervention.

老年癌症患者营养不良是发病和死亡的主要原因。应及早进行营养风险评估,以识别和治疗有可能出现癌症相关营养不良的患者。本研究旨在评估确诊为各种原因癌症的老年患者的营养状况。我们对 2013-2018 年间的老年癌症患者进行了一项单一机构前瞻性队列研究。65 岁及以上的患者在开始治疗前(第 0 天)、治疗后(第 30 天)和治疗后(第 90 天)接受了全面的老年病学评估。体重指数(BMI)和迷你营养评估(MNA)用于评估营养状况。结果显示,从治疗前(第 0 天)到治疗后(第 30 天),营养状况有所改善,但在第 90 天,MNA 分数有所下降。结果显示,体重指数在所有时间点均有所下降。这项研究证实,老年患者的癌症和抗癌治疗会导致营养不良,这表明早期营养评估和干预的重要性。
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引用次数: 0
Hypertrophic Olivary Degeneration Following Clivus Meningioma Surgery. 颅底脑膜瘤手术后的肥大性橄榄形变性
Pub Date : 2024-02-01
Nahid Mohammadzadeh, Glenn A Tung, Joseph H Friedman
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引用次数: 0
Not a Laughing Matter: When Nitrous Oxide Causes Functional Vitamin B12 Deficiency. 不是笑料:一氧化二氮导致功能性维生素 B12 缺乏症。
Pub Date : 2024-02-01
Yonathan Daniel, Sarah Freeman

Subacute combined degeneration (SCD) is an acquired neurologic complication from prolonged vitamin B12 deficiency. As a result of dorsal and lateral spinal cord column degeneration, patients present with a range of neurological symptoms, including paresthesias, ataxia, and muscle weakness. Without prompt treatment, irreversible nerve damage occurs. Here we present a young man who developed progressive ascending paresthesias and lower extremity weakness after escalated nitrous oxide use. This case highlights the importance of considering SCD from nitrous oxide toxicity when patients present with progressive ataxia, paresthesia, and lower extremity weakness.

亚急性联合变性(Subacute Combined degeneration,SCD)是一种因长期缺乏维生素 B12 而引起的后天性神经系统并发症。由于脊髓背侧和侧柱变性,患者会出现一系列神经症状,包括麻痹、共济失调和肌无力。如果不及时治疗,会造成不可逆转的神经损伤。在这里,我们介绍了一名年轻男子,他在使用笑气升级后出现了进行性上升性麻痹和下肢无力。本病例强调了当患者出现进行性共济失调、麻痹和下肢无力时考虑一氧化二氮中毒导致 SCD 的重要性。
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引用次数: 0
Pseudohypoglycemia: A Pitfall in Everyday Practice. 假性低血糖:日常实践中的一个陷阱。
Pub Date : 2024-02-01
Eric W Robbins, Taro Minami, Kamran Manzoor

Hypoglycemia is a common clinical finding, especially in the inpatient setting. However, laboratory testing may show falsely low blood glucose levels. It is crucial for clinicians to recognize the existence of pseudohypo- glycemia and know when and how to test for it.

低血糖是一种常见的临床症状,尤其是在住院环境中。然而,实验室检测可能会显示假性低血糖。临床医生必须认识到假性低血糖的存在,并知道何时以及如何进行检测。
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引用次数: 0
期刊
Rhode Island medical journal (2013)
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