Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000275
Emmy Nokaneng, Anika Fourie
{"title":"Management of Skin Tears in Vulnerable Populations from Older Adults to Critically Ill Patients: ISTAP Part 2.","authors":"Emmy Nokaneng, Anika Fourie","doi":"10.1097/ASW.0000000000000275","DOIUrl":"10.1097/ASW.0000000000000275","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"64-66"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000270
Tomer Katz, Amit Gefen
Abstract:
Objective: To investigate the impact of darker skin tones on skin tolerance to shear forces in the context of pressure injuries (PIs) and explore the mechanobiological hypothesis that people with darker skin may be at an increased PI risk due to altered biomechanical skin properties resulting from a lower water content (WC) as some literature suggests.
Methods: The authors developed a computational modeling framework simulating skin with varying Poisson ratios to represent different WC levels in the stratum corneum (SC), focusing on the effects of ethnicity and WC on mechanical stresses in superficial skin during weightbearing postures. Mechanical properties of the tissues were based on literature values. Pure compression and compression with shear were applied to the skin model.
Results: A lower Poisson ratio in the SC, indicating lower WC, is associated with higher tissue stresses and more intense stress concentrations, especially under combined compression and shear loading. The initial reduction in the Poisson ratio had the most significant impact on increased tissue loading. These results support the hypothesis that the lower WC in darker skin, associated with increased transepidermal water loss, may lead to altered biomechanical behavior and increased PI risk.
Conclusions: The modeling suggests that reduced WC and increased transepidermal water loss, notably present in darker skin tones, lead to higher stress concentrations within the SC, thus elevating the PI risk. Comprehensive clinical and biomechanical data across various skin tones are needed to improve the practice of PI prevention in individuals with darker skin.
摘要:目的研究深肤色在压力损伤(PIs)中对皮肤剪切力耐受性的影响,并探索机械生物学假说,即深色皮肤的人可能会增加压力损伤的风险,这是因为一些文献认为皮肤含水量(WC)较低导致皮肤生物力学特性发生了改变:作者开发了一个计算建模框架,模拟具有不同泊松比的皮肤,以表示角质层(SC)中不同的含水量水平,重点研究在负重姿势时种族和含水量对表层皮肤机械应力的影响。组织的机械性能以文献值为基础。对皮肤模型施加了纯压缩和带剪切力的压缩:结果:SC 的泊松比越低,表明 WC 越低,则组织应力越大,应力集中程度越高,尤其是在压缩和剪切联合加载的情况下。泊松比的初始降低对组织负荷增加的影响最大。这些结果支持这样的假设,即深色皮肤中较低的 WC 与经表皮失水增加有关,可能会导致生物力学行为改变和 PI 风险增加:建模结果表明,深肤色皮肤的 WC 值降低和经表皮失水增加会导致 SC 内应力浓度升高,从而增加 PI 风险。需要全面掌握不同肤色人群的临床和生物力学数据,以改进深肤色人群的 PI 预防实践。
{"title":"Impact of Skin Tone on Skin Tolerance to Shear in the Context of Pressure Injuries: Theory and Computer Modeling.","authors":"Tomer Katz, Amit Gefen","doi":"10.1097/ASW.0000000000000270","DOIUrl":"10.1097/ASW.0000000000000270","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>To investigate the impact of darker skin tones on skin tolerance to shear forces in the context of pressure injuries (PIs) and explore the mechanobiological hypothesis that people with darker skin may be at an increased PI risk due to altered biomechanical skin properties resulting from a lower water content (WC) as some literature suggests.</p><p><strong>Methods: </strong>The authors developed a computational modeling framework simulating skin with varying Poisson ratios to represent different WC levels in the stratum corneum (SC), focusing on the effects of ethnicity and WC on mechanical stresses in superficial skin during weightbearing postures. Mechanical properties of the tissues were based on literature values. Pure compression and compression with shear were applied to the skin model.</p><p><strong>Results: </strong>A lower Poisson ratio in the SC, indicating lower WC, is associated with higher tissue stresses and more intense stress concentrations, especially under combined compression and shear loading. The initial reduction in the Poisson ratio had the most significant impact on increased tissue loading. These results support the hypothesis that the lower WC in darker skin, associated with increased transepidermal water loss, may lead to altered biomechanical behavior and increased PI risk.</p><p><strong>Conclusions: </strong>The modeling suggests that reduced WC and increased transepidermal water loss, notably present in darker skin tones, lead to higher stress concentrations within the SC, thus elevating the PI risk. Comprehensive clinical and biomechanical data across various skin tones are needed to improve the practice of PI prevention in individuals with darker skin.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"105-111"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000277
Kathleen D Schaum
{"title":"Which Technologies and Procedures Does Medicare Cover for Pressure Injuries?","authors":"Kathleen D Schaum","doi":"10.1097/ASW.0000000000000277","DOIUrl":"10.1097/ASW.0000000000000277","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"62-63"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To evaluate the experiences of caregivers (patients' companions and nurses) in managing pressure injuries (PIs) in patients in palliative care.
Methods: Included in this qualitative phenomenologic study were 10 caregivers (five patient companions and five nurses) involved in the care of five patients hospitalized in the palliative care unit of a single facility between January and March 2023. The research data were collected through face-to-face, in-depth interviews using semistructured interviews.
Results: Two main themes emerged from the interviews: "approach to care" and "factors affecting the care of PIs." Regarding "approach to care," subsidiary analytic themes included "management of PIs" and "feelings." For "factors affecting the care of PIs," analytic themes were "level of knowledge," "facilitators," "difficulty in caregiving," and "experience of care."
Conclusions: The interviewed nurses and patients' companions identified factors facilitating and complicating the effective management of PIs, knowledge of which may steer the development of strategies by healthcare providers and administrators that meet the needs of healthcare personnel. These findings may contribute to creating interventions and policies for managing PIs, potentially increasing the patients' quality of life.
{"title":"Evaluation of Caregivers' Experiences in the Management of Pressure Injuries in Palliative Care Patients: A Phenomenologic Study.","authors":"Sevil Pamuk Cebeci, Pınar Duru, Zeynep Irmak Kaya, Mihraç Topçu","doi":"10.1097/ASW.0000000000000273","DOIUrl":"10.1097/ASW.0000000000000273","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>To evaluate the experiences of caregivers (patients' companions and nurses) in managing pressure injuries (PIs) in patients in palliative care.</p><p><strong>Methods: </strong>Included in this qualitative phenomenologic study were 10 caregivers (five patient companions and five nurses) involved in the care of five patients hospitalized in the palliative care unit of a single facility between January and March 2023. The research data were collected through face-to-face, in-depth interviews using semistructured interviews.</p><p><strong>Results: </strong>Two main themes emerged from the interviews: \"approach to care\" and \"factors affecting the care of PIs.\" Regarding \"approach to care,\" subsidiary analytic themes included \"management of PIs\" and \"feelings.\" For \"factors affecting the care of PIs,\" analytic themes were \"level of knowledge,\" \"facilitators,\" \"difficulty in caregiving,\" and \"experience of care.\"</p><p><strong>Conclusions: </strong>The interviewed nurses and patients' companions identified factors facilitating and complicating the effective management of PIs, knowledge of which may steer the development of strategies by healthcare providers and administrators that meet the needs of healthcare personnel. These findings may contribute to creating interventions and policies for managing PIs, potentially increasing the patients' quality of life.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"E18-E24"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000278
{"title":"Hospitalized Pediatric Patients: Risk Factors Related to the Development of Immobility-Related and Medical Device-Related Pressure Injuries.","authors":"","doi":"10.1097/ASW.0000000000000278","DOIUrl":"10.1097/ASW.0000000000000278","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"32"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000074
Michele Deppisch, Ryan Alvarez, Brent Larson, Dave Newton, Steven Saliga, Barbara Samson, Frank Sauser, Sara Tackson, Erica Thibault, Kristen Thurman, Jackie Todd
{"title":"Clinical Relevance of Microclimate Tests on Support Surfaces.","authors":"Michele Deppisch, Ryan Alvarez, Brent Larson, Dave Newton, Steven Saliga, Barbara Samson, Frank Sauser, Sara Tackson, Erica Thibault, Kristen Thurman, Jackie Todd","doi":"10.1097/ASW.0000000000000074","DOIUrl":"10.1097/ASW.0000000000000074","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"71-75"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000280
Esra Özkan, Dilek Çilingir
Abstract:
Background: Few studies have investigated the application of massage to bony prominences, and international guidelines do not currently recommend additional massage in these areas.
Objective: To investigate the impact of the effleurage technique, a component of classical massage known for its clinical applicability and practicality, in preventing pressure injuries (PIs).
Methods: The study focused on bedridden patients in the ICU of a state hospital. The sample included patients admitted between July 1, 2021, and November 30, 2021, without preexisting PIs. Using a randomized controlled trial design with simple randomization, routine nursing care was provided to the control group of 30 patients, and the experimental group of 30 patients received classical massage (effleurage technique) in addition to routine care. Both groups were followed up for an average of 12 days using various assessment tools, including a patient information form, the Braden Risk Assessment Scale, the Pressure Wound Staging Form, and an experimental/control group follow-up form.
Results: The research results revealed a statistically significant impact of massage application on preventing PIs (P < .05). The average day of PI development was 10.93 ± 2.31 in the experimental group and 6.79 ± 4.42 in the control group.
Conclusions: The study findings suggest that the effleurage technique, as part of classical massage, can be integrated into nursing practices to effectively prevent PIs.
{"title":"Evaluation of the Effect of Massage on Pressure Injury Prevention among Intensive Care Patients: A Randomized Controlled Study.","authors":"Esra Özkan, Dilek Çilingir","doi":"10.1097/ASW.0000000000000280","DOIUrl":"10.1097/ASW.0000000000000280","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Background: </strong>Few studies have investigated the application of massage to bony prominences, and international guidelines do not currently recommend additional massage in these areas.</p><p><strong>Objective: </strong>To investigate the impact of the effleurage technique, a component of classical massage known for its clinical applicability and practicality, in preventing pressure injuries (PIs).</p><p><strong>Methods: </strong>The study focused on bedridden patients in the ICU of a state hospital. The sample included patients admitted between July 1, 2021, and November 30, 2021, without preexisting PIs. Using a randomized controlled trial design with simple randomization, routine nursing care was provided to the control group of 30 patients, and the experimental group of 30 patients received classical massage (effleurage technique) in addition to routine care. Both groups were followed up for an average of 12 days using various assessment tools, including a patient information form, the Braden Risk Assessment Scale, the Pressure Wound Staging Form, and an experimental/control group follow-up form.</p><p><strong>Results: </strong>The research results revealed a statistically significant impact of massage application on preventing PIs (P < .05). The average day of PI development was 10.93 ± 2.31 in the experimental group and 6.79 ± 4.42 in the control group.</p><p><strong>Conclusions: </strong>The study findings suggest that the effleurage technique, as part of classical massage, can be integrated into nursing practices to effectively prevent PIs.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"E25-E31"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000279
{"title":"New Pressure Injury Evidence and the Upcoming 4th Edition of the EPUAP/NPPIAP/PPPIA International Pressure Injury Practice Guideline.","authors":"","doi":"10.1097/ASW.0000000000000279","DOIUrl":"10.1097/ASW.0000000000000279","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"61"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000271
Ann Marie Nie, Barbara Delmore
General purpose: To review risk factors for the development of medical device-related and immobility-related pressure injuries in hospitalized pediatric patients.
Target audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and registered nurses with an interest in skin and wound care.
Learning objectives/outcomes: After participating in this educational activity, the participant will be better able to:1. Describe trends in pressure injuries (PIs) for hospitalized pediatric patients as summarized in current literature.2. Identify risk factors predictive of medical device-related and immobility-related PIs in hospitalized pediatric patients.3. Summarize the methodology used to understand risk factors for developing PIs in the hospitalized pediatric patient population.
{"title":"Hospitalized Pediatric Patients: Risk Factors Related to the Development of Immobility-Related and Medical Device-Related Pressure Injuries.","authors":"Ann Marie Nie, Barbara Delmore","doi":"10.1097/ASW.0000000000000271","DOIUrl":"10.1097/ASW.0000000000000271","url":null,"abstract":"<p><strong>General purpose: </strong>To review risk factors for the development of medical device-related and immobility-related pressure injuries in hospitalized pediatric patients.</p><p><strong>Target audience: </strong>This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and registered nurses with an interest in skin and wound care.</p><p><strong>Learning objectives/outcomes: </strong>After participating in this educational activity, the participant will be better able to:1. Describe trends in pressure injuries (PIs) for hospitalized pediatric patients as summarized in current literature.2. Identify risk factors predictive of medical device-related and immobility-related PIs in hospitalized pediatric patients.3. Summarize the methodology used to understand risk factors for developing PIs in the hospitalized pediatric patient population.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"76-85"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01DOI: 10.1097/ASW.0000000000000272
Antonio Ramos-Sánchez, María Jesús Martínez-Beltrán, Blanca Egea-Zerolo, María Del Carmen Águila-Pollo, Juan M Arribas-Marín, David Fernández-Ayuso, Ana S F Ribeiro
Abstract:
Objective: To estimate the increase in length of stay and cost of illness of pressure injuries (PIs) in the inpatient area of a socio-health center.
Methods: This was a retrospective cohort study that included a consecutive sampling of patients admitted to the inpatient programs of a socio-healthcare center between January 1, 2016, and December 31, 2018. Data were retrospectively extracted from patients' electronic health records.
Results: During the study period 4,062 patients were admitted to the different hospitalization programs. The patients' mean age was 75.34 ± 13.69 years, and 51.2% of them were men. Of these, 1,421 patients had PIs, and 318 patients had to prolong their hospital stay due to PIs. These 318 patients were admitted 12,089 days longer (mean of 38.01 ± 41.49 days per patient) than patients without a PI, representing an expense of €1,381,006 (US $1,430,722). The cost of illness in the period under study was estimated at €1,922,049 (US $1,991,212). The average cost of PI treatment per patient was €1,352.60 ± €3,351.43 (US $1,401.29 ± $3,472.08), and the average cost of treatment until complete resolution of a PI was €2,064.65 ± €4,282.48 (US $1,470.79 ± $4,436.65). The cost of treatment ranged from €1,419.68 ± €3,100.47 (US $2,138.98 ± $3,212.09) for stage 1 PIs to €6,299.31 ± €10,000.57 (US $6,526.08 ± $10,360.59) for stage 4 PIs.
Conclusions: This study highlights the significant health and economic impacts of PIs in the inpatient area of a socio-health center. The findings emphasize the necessity of effective prevention strategies to mitigate the occurrence of PIs and their associated costs. By understanding the financial burden of PIs, healthcare providers and policymakers can make informed decisions to improve resource allocation, enhance patient care, and reduce financial strain on the healthcare system.
{"title":"Cost of Illness of Pressure Injuries in the Inpatient Area of a Socio-Health Center in Spain.","authors":"Antonio Ramos-Sánchez, María Jesús Martínez-Beltrán, Blanca Egea-Zerolo, María Del Carmen Águila-Pollo, Juan M Arribas-Marín, David Fernández-Ayuso, Ana S F Ribeiro","doi":"10.1097/ASW.0000000000000272","DOIUrl":"10.1097/ASW.0000000000000272","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>To estimate the increase in length of stay and cost of illness of pressure injuries (PIs) in the inpatient area of a socio-health center.</p><p><strong>Methods: </strong>This was a retrospective cohort study that included a consecutive sampling of patients admitted to the inpatient programs of a socio-healthcare center between January 1, 2016, and December 31, 2018. Data were retrospectively extracted from patients' electronic health records.</p><p><strong>Results: </strong>During the study period 4,062 patients were admitted to the different hospitalization programs. The patients' mean age was 75.34 ± 13.69 years, and 51.2% of them were men. Of these, 1,421 patients had PIs, and 318 patients had to prolong their hospital stay due to PIs. These 318 patients were admitted 12,089 days longer (mean of 38.01 ± 41.49 days per patient) than patients without a PI, representing an expense of €1,381,006 (US $1,430,722). The cost of illness in the period under study was estimated at €1,922,049 (US $1,991,212). The average cost of PI treatment per patient was €1,352.60 ± €3,351.43 (US $1,401.29 ± $3,472.08), and the average cost of treatment until complete resolution of a PI was €2,064.65 ± €4,282.48 (US $1,470.79 ± $4,436.65). The cost of treatment ranged from €1,419.68 ± €3,100.47 (US $2,138.98 ± $3,212.09) for stage 1 PIs to €6,299.31 ± €10,000.57 (US $6,526.08 ± $10,360.59) for stage 4 PIs.</p><p><strong>Conclusions: </strong>This study highlights the significant health and economic impacts of PIs in the inpatient area of a socio-health center. The findings emphasize the necessity of effective prevention strategies to mitigate the occurrence of PIs and their associated costs. By understanding the financial burden of PIs, healthcare providers and policymakers can make informed decisions to improve resource allocation, enhance patient care, and reduce financial strain on the healthcare system.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"38 2","pages":"E6-E11"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}