首页 > 最新文献

The Lancet regional health. Southeast Asia最新文献

英文 中文
Grappling Covishield fear in India: the urgent need for strong countermeasures to build vaccine confidence 消除印度人对疫苗的恐惧:亟需采取有力对策建立疫苗信心
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-11 DOI: 10.1016/j.lansea.2024.100447
Abhijit Poddar , S.R. Rao
{"title":"Grappling Covishield fear in India: the urgent need for strong countermeasures to build vaccine confidence","authors":"Abhijit Poddar , S.R. Rao","doi":"10.1016/j.lansea.2024.100447","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100447","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000970/pdfft?md5=f2d09cbb2f62a395e73bbb5051cb5157&pid=1-s2.0-S2772368224000970-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intervention to kitchen environment for improving birth outcomes 干预厨房环境,改善分娩结果
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-08 DOI: 10.1016/j.lansea.2024.100446
Nobuo Tsuboi , Wendy E. Hoy , John F. Bertram
{"title":"Intervention to kitchen environment for improving birth outcomes","authors":"Nobuo Tsuboi , Wendy E. Hoy , John F. Bertram","doi":"10.1016/j.lansea.2024.100446","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100446","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000969/pdfft?md5=3cddef7216ee1ffef21910c2a987832b&pid=1-s2.0-S2772368224000969-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yellow phosphorus poisoning: is preemptive PLEX therapy feasible? 黄磷中毒:先期 PLEX 治疗可行吗?
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-02 DOI: 10.1016/j.lansea.2024.100444
Harikumar Nair, Amal Joseph
{"title":"Yellow phosphorus poisoning: is preemptive PLEX therapy feasible?","authors":"Harikumar Nair, Amal Joseph","doi":"10.1016/j.lansea.2024.100444","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100444","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000945/pdfft?md5=1b3ef59aa248b73aeac0361f4679e490&pid=1-s2.0-S2772368224000945-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141540920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exam failure suicides and policy initiatives in India 印度的考试失败自杀事件和政策举措
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-02 DOI: 10.1016/j.lansea.2024.100443
Lakshmi Vijayakumar
{"title":"Exam failure suicides and policy initiatives in India","authors":"Lakshmi Vijayakumar","doi":"10.1016/j.lansea.2024.100443","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100443","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000933/pdfft?md5=1756be3b35816e07277fe41269434214&pid=1-s2.0-S2772368224000933-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141540838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rise in social media's harms 社交媒体危害的增加
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 DOI: 10.1016/j.lansea.2024.100445
The Lancet Regional Health – Southeast Asia
{"title":"Rise in social media's harms","authors":"The Lancet Regional Health – Southeast Asia","doi":"10.1016/j.lansea.2024.100445","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100445","url":null,"abstract":"","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000957/pdfft?md5=35880d6b423264e0af71950e40730fc1&pid=1-s2.0-S2772368224000957-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness analysis of low-sodium potassium-rich salt substitutes in Indonesia: an equity modelling study 印度尼西亚富含钾的低钠盐替代品的成本效益分析:公平模型研究
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 DOI: 10.1016/j.lansea.2024.100432
Leopold Ndemnge Aminde , Wahyu Pudji Nugraheni , Rofingatul Mubasyiroh , Tety Rachmawati , Febi Dwirahmadi , Santi Martini , Nunik Kusumawardani , J Lennert Veerman

Background

Evidence suggests low-sodium potassium-rich salt substitutes (LSSS) are effective in reducing blood pressure (BP). However, the health and economic impacts of LSSS in Indonesia are currently unknown.

Methods

We developed a proportional multistate lifetable Markov model to assess a government-led strategy implementing the use of LSSS compared to current regular salt consumption. BP data were derived from the Indonesian Basic Health Research Survey (RISKESDAS 2018), while epidemiological data were from the Global Burden of Disease 2019 study. We estimated implementation costs and the impact of changes in BP on disease events and healthcare costs, and incremental cost-effectiveness ratios. Outcomes were simulated over different time horizons for the 2019 Indonesian population overall, and by income quintiles. Probabilistic sensitivity analysis was done to capture uncertainty.

Findings

Over the first 10 years, LSSS could prevent 1.5 million non-fatal cardiovascular disease (CVD) events (8.3%–19.4% reduction) and 643,000 incident chronic kidney disease (CKD) cases (8.2% reduction), while averting over 200,000 CVD and CKD deaths (0.2%–5.2% reduction). This translated to over 24.6 million health-adjusted life years (HALYs) gained over the lifetime of the population, and reduced CVD-related health inequalities (concentration index, −0.075, 95% CI: −0.088 to −0.062). Implementation cost (US$ 1.2 billion [IDR 17.2 trillion] total; US$ 4.5 [IDR 63,665] per capita, as of July 2019) was outweighed by the net health expenditure savings (∼US$ 2 billion [IDR 27.7 trillion] total; US$ 7.3 [IDR 103,300] per capita) in the first 10 years. LSSS were cost-saving over the lifetime, and very cost-effective even with a high LSSS price.

Interpretation

Scaling the use of LSSS nationally could be a cost-saving strategy to prevent substantial cardiovascular and kidney disease burden in Indonesia.

Funding

Griffith University Postdoctoral Fellowship.

背景有证据表明,富含钾的低钠盐替代品(LSSS)可有效降低血压(BP)。方法我们建立了一个比例多态生命表马尔可夫模型,以评估与目前的常规食盐消费相比,政府主导的低钠盐替代品使用策略。血压数据来自印度尼西亚基础健康研究调查(RISKESDAS 2018),而流行病学数据则来自 2019 年全球疾病负担研究。我们估算了实施成本、血压变化对疾病事件和医疗成本的影响以及增量成本效益比。在不同的时间跨度内,我们模拟了 2019 年印尼总体人口以及五等分收入人群的结果。研究结果在最初的 10 年中,LSSS 可预防 150 万例非致命性心血管疾病(CVD)事件(减少 8.3%-19.4%)和 64.3 万例慢性肾病(CKD)病例(减少 8.2%),同时避免 20 多万例 CVD 和 CKD 死亡(减少 0.2%-5.2%)。这意味着在人口的一生中将获得超过 2,460 万个健康调整生命年(HALYs),并减少了与心血管疾病相关的健康不平等(集中指数,-0.075,95% CI:-0.088 至 -0.062)。实施成本(总计 12 亿美元[17.2 万亿印尼盾];截至 2019 年 7 月,人均 4.5 美元[63,665 印尼盾])被前 10 年节省的净医疗支出(总计 20 亿美元[27.7 万亿印尼盾];人均 7.3 美元[103,300 印尼盾])所抵消。在印度尼西亚,在全国范围内推广使用 LSSS 是一项节约成本的策略,可有效预防心血管疾病和肾脏疾病。
{"title":"Cost-effectiveness analysis of low-sodium potassium-rich salt substitutes in Indonesia: an equity modelling study","authors":"Leopold Ndemnge Aminde ,&nbsp;Wahyu Pudji Nugraheni ,&nbsp;Rofingatul Mubasyiroh ,&nbsp;Tety Rachmawati ,&nbsp;Febi Dwirahmadi ,&nbsp;Santi Martini ,&nbsp;Nunik Kusumawardani ,&nbsp;J Lennert Veerman","doi":"10.1016/j.lansea.2024.100432","DOIUrl":"10.1016/j.lansea.2024.100432","url":null,"abstract":"<div><h3>Background</h3><p>Evidence suggests low-sodium potassium-rich salt substitutes (LSSS) are effective in reducing blood pressure (BP). However, the health and economic impacts of LSSS in Indonesia are currently unknown.</p></div><div><h3>Methods</h3><p>We developed a proportional multistate lifetable Markov model to assess a government-led strategy implementing the use of LSSS compared to current regular salt consumption. BP data were derived from the Indonesian Basic Health Research Survey (RISKESDAS 2018), while epidemiological data were from the Global Burden of Disease 2019 study. We estimated implementation costs and the impact of changes in BP on disease events and healthcare costs, and incremental cost-effectiveness ratios. Outcomes were simulated over different time horizons for the 2019 Indonesian population overall, and by income quintiles. Probabilistic sensitivity analysis was done to capture uncertainty.</p></div><div><h3>Findings</h3><p>Over the first 10 years, LSSS could prevent 1.5 million non-fatal cardiovascular disease (CVD) events (8.3%–19.4% reduction) and 643,000 incident chronic kidney disease (CKD) cases (8.2% reduction), while averting over 200,000 CVD and CKD deaths (0.2%–5.2% reduction). This translated to over 24.6 million health-adjusted life years (HALYs) gained over the lifetime of the population, and reduced CVD-related health inequalities (concentration index, −0.075, 95% CI: −0.088 to −0.062). Implementation cost (US$ 1.2 billion [IDR 17.2 trillion] total; US$ 4.5 [IDR 63,665] per capita, as of July 2019) was outweighed by the net health expenditure savings (∼US$ 2 billion [IDR 27.7 trillion] total; US$ 7.3 [IDR 103,300] per capita) in the first 10 years. LSSS were cost-saving over the lifetime, and very cost-effective even with a high LSSS price.</p></div><div><h3>Interpretation</h3><p>Scaling the use of LSSS nationally could be a cost-saving strategy to prevent substantial cardiovascular and kidney disease burden in Indonesia.</p></div><div><h3>Funding</h3><p>Griffith University Postdoctoral Fellowship.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000829/pdfft?md5=1ef5ff8b3a25214b3552da75b080e183&pid=1-s2.0-S2772368224000829-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141404490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Policy implementation and recommended actions to create healthy food environments using the Healthy Food Environment Policy Index (Food-EPI): a comparative analysis in South Asia 利用健康食品环境政策指数(Food-EPI)创建健康食品环境的政策实施和建议行动:南亚比较分析
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 DOI: 10.1016/j.lansea.2024.100428
Elisa Pineda , Petya Atanasova , Nalinda Tharanga Wellappuli , Dian Kusuma , Himali Herath , Alexa Blair Segal , Stefanie Vandevijvere , Ranjit Mohan Anjana , Abu Ahmed Shamim , Saira Afzal , Fahmida Akter , Faiza Aziz , Ananya Gupta , Abu Abdullah Hanif , Mehedi Hasan , Renuka Jayatissa , Sujeet Jha , Vinitaa Jha , Prasad Katulanda , Khadija Irfan Khawaja , Marisa Miraldo

Background

The increasing prevalence of diet-related non-communicable diseases (NCDs) in South Asia is concerning, with type 2 diabetes projected to rise to 68%, compared to the global increase of 44%. Encouraging healthy diets requires stronger policies for healthier food environments.

Methods

This study reviewed and assessed food environment policies in Bangladesh, India, Pakistan, and Sri Lanka from 2020 to 2022 using the Healthy Food Environment Policy Index (Food-EPI) and compared them with global best practices. Seven policy domains and six infrastructure support domains were considered, employing 47 good practice indicators to prevent NCDs. Stakeholders from government and non-governmental sectors in South Asia (n = 148) were invited to assess policy and infrastructure support implementation using the Delphi method.

Findings

Implementation of food environment policies and infrastructure support in these countries was predominantly weak. Labelling, monitoring, and leadership policies received a moderate rating, with a focus on food safety, hygiene, and quality rather than obesity prevention. Key policy gaps prioritized for attention included front-of-pack labelling, healthy food subsidies, unhealthy food taxation, restrictions on unhealthy food promotion, and improvements in school nutrition standards to combat NCDs.

Interpretation

Urgent action is required to expand food policies beyond hygiene and food security measures. Comprehensive strategies targeting NCD prevention are crucial to combat the escalating burden of NCDs in the region.

Funding

This research was funded by the NIHR (16/136/68 and 132960) with aid from the UK Government for global health research. Petya Atanasova also acknowledges funding from the Economic and Social Research Council (ESRC) (ES/P000703/1). The views expressed are those of the authors and not necessarily of the NIHR, the UK government or the ESRC.

背景南亚地区与饮食相关的非传染性疾病(NCDs)发病率的上升令人担忧,预计 2 型糖尿病的发病率将上升至 68%,而全球的增幅为 44%。本研究利用健康食品环境政策指数(Food-EPI)对孟加拉国、印度、巴基斯坦和斯里兰卡 2020 年至 2022 年的食品环境政策进行了审查和评估,并与全球最佳实践进行了比较。研究考虑了七个政策领域和六个基础设施支持领域,采用了 47 个预防非传染性疾病的良好实践指标。来自南亚政府和非政府部门的利益相关者(n = 148)应邀采用德尔菲法对政策和基础设施支持的实施情况进行了评估。标签、监测和领导力政策获得了中等评级,重点是食品安全、卫生和质量,而不是预防肥胖。需要优先关注的主要政策差距包括包装前标签、健康食品补贴、不健康食品征税、限制不健康食品促销以及提高学校营养标准以防治非传染性疾病。针对非传染性疾病预防的综合战略对于应对该地区非传染性疾病日益加重的负担至关重要。 资金来源本研究由英国国家健康研究院(NIHR)(16/136/68 和 132960)资助,英国政府为全球健康研究提供了援助。Petya Atanasova还感谢经济与社会研究理事会(ESRC)(ES/P000703/1)的资助。文中观点仅代表作者本人,与英国国家健康研究院、英国政府或 ESRC 无关。
{"title":"Policy implementation and recommended actions to create healthy food environments using the Healthy Food Environment Policy Index (Food-EPI): a comparative analysis in South Asia","authors":"Elisa Pineda ,&nbsp;Petya Atanasova ,&nbsp;Nalinda Tharanga Wellappuli ,&nbsp;Dian Kusuma ,&nbsp;Himali Herath ,&nbsp;Alexa Blair Segal ,&nbsp;Stefanie Vandevijvere ,&nbsp;Ranjit Mohan Anjana ,&nbsp;Abu Ahmed Shamim ,&nbsp;Saira Afzal ,&nbsp;Fahmida Akter ,&nbsp;Faiza Aziz ,&nbsp;Ananya Gupta ,&nbsp;Abu Abdullah Hanif ,&nbsp;Mehedi Hasan ,&nbsp;Renuka Jayatissa ,&nbsp;Sujeet Jha ,&nbsp;Vinitaa Jha ,&nbsp;Prasad Katulanda ,&nbsp;Khadija Irfan Khawaja ,&nbsp;Marisa Miraldo","doi":"10.1016/j.lansea.2024.100428","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100428","url":null,"abstract":"<div><h3>Background</h3><p>The increasing prevalence of diet-related non-communicable diseases (NCDs) in South Asia is concerning, with type 2 diabetes projected to rise to 68%, compared to the global increase of 44%. Encouraging healthy diets requires stronger policies for healthier food environments.</p></div><div><h3>Methods</h3><p>This study reviewed and assessed food environment policies in Bangladesh, India, Pakistan, and Sri Lanka from 2020 to 2022 using the Healthy Food Environment Policy Index (Food-EPI) and compared them with global best practices. Seven policy domains and six infrastructure support domains were considered, employing 47 good practice indicators to prevent NCDs. Stakeholders from government and non-governmental sectors in South Asia (n = 148) were invited to assess policy and infrastructure support implementation using the Delphi method.</p></div><div><h3>Findings</h3><p>Implementation of food environment policies and infrastructure support in these countries was predominantly weak. Labelling, monitoring, and leadership policies received a moderate rating, with a focus on food safety, hygiene, and quality rather than obesity prevention. Key policy gaps prioritized for attention included front-of-pack labelling, healthy food subsidies, unhealthy food taxation, restrictions on unhealthy food promotion, and improvements in school nutrition standards to combat NCDs.</p></div><div><h3>Interpretation</h3><p>Urgent action is required to expand food policies beyond hygiene and food security measures. Comprehensive strategies targeting NCD prevention are crucial to combat the escalating burden of NCDs in the region.</p></div><div><h3>Funding</h3><p>This research was funded by the NIHR (16/136/68 and 132960) with aid from the UK Government for global health research. Petya Atanasova also acknowledges funding from the Economic and Social Research Council (ESRC) (ES/P000703/1). The views expressed are those of the authors and not necessarily of the NIHR, the UK government or the ESRC.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000787/pdfft?md5=6bbd099f347fff7acb86c94283b93964&pid=1-s2.0-S2772368224000787-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141481480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of geographical accessibility to COVID-19 testing facilities in Nepal (2021) 尼泊尔 COVID-19 检测设施地理可达性评估(2021 年)
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-01 DOI: 10.1016/j.lansea.2024.100436
Parvathy Krishnan Krishnakumari , Hannah Bakker , Nadia Lahrichi , Fannie L. Côté , Joaquim Gromicho , Arunkumar Govindakarnavar , Priya Jha , Saugat Shrestha , Rashmi Mulmi , Nirajan Bhusal , Deepesh Stapith , Runa Jha , Lilee Shrestha , Reuben Samuel , Dhamari Naidoo , Victor Del Rio Vilas

Background

Ensuring equitable physical access to SARS-CoV-2 testing has proven to be crucial for controlling the COVID-19 epidemic, especially in countries like Nepal with its challenging terrain. During the second wave of the pandemic in May 2021, there was immense pressure to expand the laboratory network in Nepal to ensure calibration of epidemic response. The expansion led to an increase in the number of testing facilities from 69 laboratories in May 2021 to 89 laboratories by November 2021. We assessed the equity of physical access to COVID-19 testing facilities in Nepal during 2021. Furthermore, we investigated the potential of mathematical optimisation in improving accessibility to COVID-19 testing facilities.

Methods

Based on up-to-date publicly available data sets and on the COVID-19-related daily reports published by Nepal's Ministry of Health and Population from May 1 to November 15, 2021, we measured the disparities in geographical accessibility to COVID-19 testing across Nepal at a resolution of 1 km2. In addition, we proposed an optimisation model to prescribe the best possible locations to set up testing laboratories maximizing access, and tested its potential impact in Nepal.

Findings

The analysis identified vulnerable districts where, despite ramping up efforts, physical accessibility to testing facilities remains low under two modes of travel—walking and motorized driving. Both geographical accessibility and its equality were better under the motorised mode compared with the walking mode. If motorised transportation were available to everyone, the population coverage within 60 min of any testing facility (public and private) would be close to threefold the coverage for pedestrians within the same hour: 61.4% motorised against 22.2% pedestrian access within the hour, considering the whole population of Nepal. Very low accessibility was found in most areas except those with private test centres concentrated in the capital city of Kathmandu. The hypothetical use of mathematical optimisation to select 20 laboratories to add to the original 69 could have improved access from the observed 61.4% offered by the laboratories operating in November to 71.4%, if those 20 could be chosen optimally from all existing healthcare facilities in Nepal. In mountainous terrain, accessibility is very low and could not be improved, even considering all existing healthcare facilities as potential testing locations.

Interpretation

The findings related to geographical accessibility to COVID-19 testing facilities should provide valuable information for health-related planning in Nepal, especially in emergencies where data might be limited and decisions time-sensitive. The potential use of publicly available data and mathematical optimisation could be considered in the future.

Funding

WHO Special Programme for Research and Tr

背景事实证明,确保公平地获得 SARS-CoV-2 检测服务对于控制 COVID-19 的流行至关重要,尤其是在尼泊尔这样地形复杂的国家。在 2021 年 5 月的第二波疫情中,尼泊尔面临着扩大实验室网络的巨大压力,以确保疫情应对措施的校准。这一扩张导致检测设施的数量从 2021 年 5 月的 69 个实验室增加到 2021 年 11 月的 89 个实验室。我们对 2021 年期间尼泊尔 COVID-19 检测设施的实际使用公平性进行了评估。方法基于最新的公开数据集以及尼泊尔卫生与人口部发布的 2021 年 5 月 1 日至 11 月 15 日 COVID-19 相关日报,我们以 1 平方公里的分辨率测量了尼泊尔 COVID-19 检测的地理可达性差异。此外,我们还提出了一个优化模型,以确定设立检测实验室的最佳地点,从而最大限度地提高检测的可及性,并测试了该模型在尼泊尔的潜在影响。分析发现,尽管尼泊尔加大了工作力度,但在步行和机动车驾驶这两种出行方式下,检测设施的实际可及性仍然很低。与步行模式相比,机动车模式的地理可达性和平等性都更好。如果人人都能使用机动车,那么在同一小时内,任何检测设施(公共和私人)60 分钟内的人口覆盖率将接近行人的三倍:就尼泊尔全国人口而言,一小时内机动车的覆盖率为 61.4%,而行人的覆盖率为 22.2%。除了那些集中在首都加德满都的私人测试中心外,大多数地区的可达性都很低。如果能从尼泊尔现有的所有医疗机构中最优化地选择这 20 家实验室,那么假设使用数学优化方法在原有的 69 家实验室基础上再选择 20 家实验室,就能将 11 月份观察到的 61.4% 的实验室可及性提高到 71.4%。有关 COVID-19 检测设施地理可达性的研究结果将为尼泊尔的健康相关规划提供有价值的信息,尤其是在数据可能有限且决策具有时间敏感性的紧急情况下。未来可能会考虑使用公开数据和数学优化方法。
{"title":"Assessment of geographical accessibility to COVID-19 testing facilities in Nepal (2021)","authors":"Parvathy Krishnan Krishnakumari ,&nbsp;Hannah Bakker ,&nbsp;Nadia Lahrichi ,&nbsp;Fannie L. Côté ,&nbsp;Joaquim Gromicho ,&nbsp;Arunkumar Govindakarnavar ,&nbsp;Priya Jha ,&nbsp;Saugat Shrestha ,&nbsp;Rashmi Mulmi ,&nbsp;Nirajan Bhusal ,&nbsp;Deepesh Stapith ,&nbsp;Runa Jha ,&nbsp;Lilee Shrestha ,&nbsp;Reuben Samuel ,&nbsp;Dhamari Naidoo ,&nbsp;Victor Del Rio Vilas","doi":"10.1016/j.lansea.2024.100436","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100436","url":null,"abstract":"<div><h3>Background</h3><p>Ensuring equitable physical access to SARS-CoV-2 testing has proven to be crucial for controlling the COVID-19 epidemic, especially in countries like Nepal with its challenging terrain. During the second wave of the pandemic in May 2021, there was immense pressure to expand the laboratory network in Nepal to ensure calibration of epidemic response. The expansion led to an increase in the number of testing facilities from 69 laboratories in May 2021 to 89 laboratories by November 2021. We assessed the equity of physical access to COVID-19 testing facilities in Nepal during 2021. Furthermore, we investigated the potential of mathematical optimisation in improving accessibility to COVID-19 testing facilities.</p></div><div><h3>Methods</h3><p>Based on up-to-date publicly available data sets and on the COVID-19-related daily reports published by Nepal's Ministry of Health and Population from May 1 to November 15, 2021, we measured the disparities in geographical accessibility to COVID-19 testing across Nepal at a resolution of 1 km<sup>2</sup>. In addition, we proposed an optimisation model to prescribe the best possible locations to set up testing laboratories maximizing access, and tested its potential impact in Nepal.</p></div><div><h3>Findings</h3><p>The analysis identified vulnerable districts where, despite ramping up efforts, physical accessibility to testing facilities remains low under two modes of travel—walking and motorized driving. Both geographical accessibility and its equality were better under the motorised mode compared with the walking mode. If motorised transportation were available to everyone, the population coverage within 60 min of any testing facility (public and private) would be close to threefold the coverage for pedestrians within the same hour: 61.4% motorised against 22.2% pedestrian access within the hour, considering the whole population of Nepal. Very low accessibility was found in most areas except those with private test centres concentrated in the capital city of Kathmandu. The hypothetical use of mathematical optimisation to select 20 laboratories to add to the original 69 could have improved access from the observed 61.4% offered by the laboratories operating in November to 71.4%, if those 20 could be chosen optimally from all existing healthcare facilities in Nepal. In mountainous terrain, accessibility is very low and could not be improved, even considering all existing healthcare facilities as potential testing locations.</p></div><div><h3>Interpretation</h3><p>The findings related to geographical accessibility to COVID-19 testing facilities should provide valuable information for health-related planning in Nepal, especially in emergencies where data might be limited and decisions time-sensitive. The potential use of publicly available data and mathematical optimisation could be considered in the future.</p></div><div><h3>Funding</h3><p>WHO Special Programme for <span>Research and Tr","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000866/pdfft?md5=03b622b168e53b64f3344c374458c213&pid=1-s2.0-S2772368224000866-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicenter, randomized, controlled comparative-effectiveness study comparing virtual reality to sedation and standard local anesthetic for pain and anxiety during epidural steroid injections 虚拟现实与镇静剂和标准局麻药治疗硬膜外类固醇注射过程中的疼痛和焦虑的多中心随机对照比较效果研究
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-25 DOI: 10.1016/j.lansea.2024.100437
Steven P. Cohen , Tina L. Doshi , COL Sithapan Munjupong , CeCe Qian , Pornpan Chalermkitpanit , Patt Pannangpetch , Kamolporn Noragrai , Eric J. Wang , Kayode A. Williams , Paul J. Christo , Pramote Euasobhon , Jason Ross , Eellan Sivanesan , Supak Ukritchon , Nuj Tontisirin

Background

The use of sedation during interventional procedures has continued to rise resulting in increased costs, complications and reduced validity during diagnostic injections, prompting a search for alternatives. Virtual reality (VR) has been shown to reduce pain and anxiety during painful procedures, but no studies have compared it to a control and active comparator for a pain-alleviating procedure. The main objective of this study was to determine whether VR reduces procedure-related pain and other outcomes for epidural steroid injections (ESI).

Methods

A randomized controlled trial was conducted in 146 patients undergoing an ESI at 6 hospitals in Thailand and the United States. Patients were allocated to receive immersive VR with local anesthetic, sedation with midazolam and fentanyl plus local anesthetic, or local anesthetic alone. The primary outcome was procedure-related pain recorded on a 0-10 scale. Other immediate-term outcome measures were pain from a standardized subcutaneous skin wheal, procedure-related anxiety, ability to communicate, satisfaction, and time to discharge. Intermediate-term outcome measures at 4 weeks included back and leg pain scores, function, and success defined as a ≥2-point decrease in average leg pain coupled with a score ≥5/7 on a Patient Global Impression of Change scale.

Findings

Procedure-related pain scores with both VR (mean 3.7 (SD 2.5)) and sedation (mean 3.2 (SD 3.0)) were lower compared to control (mean 5.2 (SD 3.1); mean differences −1.5 (−2.7, −0.4) and −2.1 (−3.3, −0.9), respectively), but VR and sedation scores did not significantly differ (mean difference 0.5 (−0.6, 1.7)). Among secondary outcomes, communication was decreased in the sedation group (mean 3.7 (SD 0.9)) compared to the VR group (mean 4.1 (SD 0.5); mean difference 0.4 (0.1, 0.6)), but neither VR nor sedation was different than control. The trends favoring sedation and VR over control for procedure-related anxiety and satisfaction were not statistically significant. Post-procedural recovery time was longer for the sedation group compared to both VR and control groups. There were no meaningful intermediate-term differences between groups except that medication reduction was lowest in the control group.

Interpretation

VR provides comparable benefit to sedation for procedure-related pain, anxiety and satisfaction, but with fewer side effects, superior communication and a shorter recovery period.

Funding

Funded in part by grants from MIRROR, Uniformed Services University of the Health Sciences, U.S. Dept. of Defense, grant # HU00011920011. Equipment was provided by Harvard MedTech, Las Vegas, NV.

背景介入治疗过程中使用镇静剂的情况不断增加,导致成本增加、并发症增多以及诊断性注射的有效性降低,这促使人们寻找替代方法。虚拟现实(VR)已被证明可以减轻痛苦手术中的疼痛和焦虑,但还没有研究将其与减轻疼痛手术的对照组和活性比较组进行比较。本研究的主要目的是确定虚拟现实是否能减轻硬膜外类固醇注射(ESI)过程中与手术相关的疼痛及其他结果。方法在泰国和美国的 6 家医院对 146 名接受 ESI 的患者进行了随机对照试验。患者被分配接受沉浸式 VR 与局部麻醉、咪达唑仑和芬太尼镇静剂加局部麻醉或仅局部麻醉。主要结果是以0-10分制记录的手术相关疼痛。其他近期疗效指标包括来自标准化皮下肿块的疼痛、与手术相关的焦虑、沟通能力、满意度和出院时间。4 周时的中期结果测量包括背部和腿部疼痛评分、功能和成功率,成功率的定义是腿部疼痛平均值下降≥2 分,同时患者总体变化印象量表评分≥5/7。与对照组(平均 5.2 (SD 3.1);平均差异分别为 -1.5 (-2.7, -0.4) 和 -2.1 (-3.3, -0.9))相比,VR(平均 3.2 (SD 3.0))和镇静(平均 3.2 (SD 3.0))的手术相关疼痛评分均较低,但 VR 和镇静评分无显著差异(平均差异为 0.5 (-0.6, 1.7))。在次要结果中,镇静组的沟通能力(平均 3.7 (SD 0.9))比 VR 组(平均 4.1 (SD 0.5);平均差异 0.4 (0.1, 0.6))有所下降,但 VR 和镇静与对照组相比均无差异。在与手术相关的焦虑和满意度方面,镇静和 VR 组优于对照组的趋势没有统计学意义。与 VR 组和对照组相比,镇静组的术后恢复时间更长。除了对照组用药量减少最少外,各组之间没有明显的中期差异。设备由内华达州拉斯维加斯的哈佛医疗技术公司提供。
{"title":"Multicenter, randomized, controlled comparative-effectiveness study comparing virtual reality to sedation and standard local anesthetic for pain and anxiety during epidural steroid injections","authors":"Steven P. Cohen ,&nbsp;Tina L. Doshi ,&nbsp;COL Sithapan Munjupong ,&nbsp;CeCe Qian ,&nbsp;Pornpan Chalermkitpanit ,&nbsp;Patt Pannangpetch ,&nbsp;Kamolporn Noragrai ,&nbsp;Eric J. Wang ,&nbsp;Kayode A. Williams ,&nbsp;Paul J. Christo ,&nbsp;Pramote Euasobhon ,&nbsp;Jason Ross ,&nbsp;Eellan Sivanesan ,&nbsp;Supak Ukritchon ,&nbsp;Nuj Tontisirin","doi":"10.1016/j.lansea.2024.100437","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100437","url":null,"abstract":"<div><h3>Background</h3><p>The use of sedation during interventional procedures has continued to rise resulting in increased costs, complications and reduced validity during diagnostic injections, prompting a search for alternatives. Virtual reality (VR) has been shown to reduce pain and anxiety during painful procedures, but no studies have compared it to a control and active comparator for a pain-alleviating procedure. The main objective of this study was to determine whether VR reduces procedure-related pain and other outcomes for epidural steroid injections (ESI).</p></div><div><h3>Methods</h3><p>A randomized controlled trial was conducted in 146 patients undergoing an ESI at 6 hospitals in Thailand and the United States. Patients were allocated to receive immersive VR with local anesthetic, sedation with midazolam and fentanyl plus local anesthetic, or local anesthetic alone. The primary outcome was procedure-related pain recorded on a 0-10 scale. Other immediate-term outcome measures were pain from a standardized subcutaneous skin wheal, procedure-related anxiety, ability to communicate, satisfaction, and time to discharge. Intermediate-term outcome measures at 4 weeks included back and leg pain scores, function, and success defined as a ≥2-point decrease in average leg pain coupled with a score ≥5/7 on a Patient Global Impression of Change scale.</p></div><div><h3>Findings</h3><p>Procedure-related pain scores with both VR (mean 3.7 (SD 2.5)) and sedation (mean 3.2 (SD 3.0)) were lower compared to control (mean 5.2 (SD 3.1); mean differences −1.5 (−2.7, −0.4) and −2.1 (−3.3, −0.9), respectively), but VR and sedation scores did not significantly differ (mean difference 0.5 (−0.6, 1.7)). Among secondary outcomes, communication was decreased in the sedation group (mean 3.7 (SD 0.9)) compared to the VR group (mean 4.1 (SD 0.5); mean difference 0.4 (0.1, 0.6)), but neither VR nor sedation was different than control. The trends favoring sedation and VR over control for procedure-related anxiety and satisfaction were not statistically significant. Post-procedural recovery time was longer for the sedation group compared to both VR and control groups. There were no meaningful intermediate-term differences between groups except that medication reduction was lowest in the control group.</p></div><div><h3>Interpretation</h3><p>VR provides comparable benefit to sedation for procedure-related pain, anxiety and satisfaction, but with fewer side effects, superior communication and a shorter recovery period.</p></div><div><h3>Funding</h3><p>Funded in part by grants from <span>MIRROR</span>, <span>Uniformed Services University of the Health Sciences</span>, U.S. Dept. of Defense, grant # HU00011920011. Equipment was provided by Harvard MedTech, Las Vegas, NV.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000878/pdfft?md5=a12dd7047f7cc59c06fbc36c55111fad&pid=1-s2.0-S2772368224000878-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Universal health coverage in Pakistan: exploring the landscape of the health system, health seeking behaviours, and utilization of health services 巴基斯坦的全民医保:探索卫生系统、求医行为和医疗服务利用情况
IF 5 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-24 DOI: 10.1016/j.lansea.2024.100440
Babar Tasneem Shaikh

The attainment of the noble objective of Universal Health Coverage (UHC)- ‘leaving no one behind’ necessitates sufficient financial resources, an ample supply of skilled healthcare professionals, and the availability of essential services as part of a basic package This paper presents an analysis of the health system, health seeking behaviours and health service utilization en route to UHC in Pakistan. We have used the UHC 14 tracer indicators of service coverage to see where Pakistan stands, what are the gaps and what needs to be done. Pakistan clearly is lagging behind its neighboring countries. The country's health system ought to work on health seeking behaviours and broader determinants of health. The pursuit of UHC demands a shared responsibility and collective action, with stakeholders from different sectors uniting their efforts and expertise. Together, they can establish robust systems, design comprehensive policies, allocate adequate resources, and implement interventions that transcend disciplinary boundaries.

要实现全民健康覆盖(UHC)的崇高目标--"不让一个人掉队",就必须有充足的财政资源、充足的熟练医疗保健专业人员以及作为基本一揽子服务一部分的基本服务。我们使用了全民健康计划的 14 项服务覆盖跟踪指标,以了解巴基斯坦的现状、差距以及需要采取的措施。巴基斯坦显然落后于邻国。该国的卫生系统应致力于改善求医行为和更广泛的健康决定因素。要实现全民健康目标,就必须分担责任,采取集体行动,来自不同部门的利益攸关方必须齐心协力,发挥各自的专长。通过共同努力,他们可以建立健全的系统,制定全面的政策,分配充足的资源,并实施超越学科界限的干预措施。
{"title":"Universal health coverage in Pakistan: exploring the landscape of the health system, health seeking behaviours, and utilization of health services","authors":"Babar Tasneem Shaikh","doi":"10.1016/j.lansea.2024.100440","DOIUrl":"https://doi.org/10.1016/j.lansea.2024.100440","url":null,"abstract":"<div><p>The attainment of the noble objective of Universal Health Coverage (UHC)- ‘leaving no one behind’ necessitates sufficient financial resources, an ample supply of skilled healthcare professionals, and the availability of essential services as part of a basic package This paper presents an analysis of the health system, health seeking behaviours and health service utilization <em>en route</em> to UHC in Pakistan. We have used the UHC 14 tracer indicators of service coverage to see where Pakistan stands, what are the gaps and what needs to be done. Pakistan clearly is lagging behind its neighboring countries. The country's health system ought to work on health seeking behaviours and broader determinants of health. The pursuit of UHC demands a shared responsibility and collective action, with stakeholders from different sectors uniting their efforts and expertise. Together, they can establish robust systems, design comprehensive policies, allocate adequate resources, and implement interventions that transcend disciplinary boundaries.</p></div>","PeriodicalId":75136,"journal":{"name":"The Lancet regional health. Southeast Asia","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772368224000908/pdfft?md5=8551e40596ab9de2502d8bc0d11dba52&pid=1-s2.0-S2772368224000908-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Lancet regional health. Southeast Asia
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1