Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.cc01
M. Cabrera-Martín, P. R. Fernández, M. Navas, P. Pérez-Segura, M. Y. Fuertes, J. B. Albacar, J. A. C. Sánchez, L. O. Medina, J. C. Delgado
Sometimes, the clinical presentation of a brain tumour mimics that of stroke or viceversa. In these cases it is useful to evaluate follow-up with MR. The coregistration of PET and MR images improves the diagnostic performance of both techniques. In the area of interest, FDG uptake of any degree, with reference to the adjacent brain tissue uptake, should be considered suggestive of tumor if it corresponds to brain injury in MR, even when the FDG uptake is equal to or lower than that of the normal cerebral cortex. We present a case in which coregistration of images from both techniques contributed to the differential diagnosis of stroke and high-grade glioma, whole-body PET/CT ruled out metastatic etiology, and the results led to surgery.
{"title":"High Grade tumor vs stroke. Utility of PET and MRI corregistration","authors":"M. Cabrera-Martín, P. R. Fernández, M. Navas, P. Pérez-Segura, M. Y. Fuertes, J. B. Albacar, J. A. C. Sánchez, L. O. Medina, J. C. Delgado","doi":"10.32440/ar.2021.138.02.cc01","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.cc01","url":null,"abstract":"Sometimes, the clinical presentation of a brain tumour mimics that of stroke or viceversa. In these cases it is useful to evaluate follow-up with MR. The coregistration of PET and MR images improves the diagnostic performance of both techniques. In the area of interest, FDG uptake of any degree, with reference to the adjacent brain tissue uptake, should be considered suggestive of tumor if it corresponds to brain injury in MR, even when the FDG uptake is equal to or lower than that of the normal cerebral cortex. We present a case in which coregistration of images from both techniques contributed to the differential diagnosis of stroke and high-grade glioma, whole-body PET/CT ruled out metastatic etiology, and the results led to surgery.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45118236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.cc02
A. Oprişan, M. Solana
Postabortion ovarian vein septic thrombophlebitis is a very rare variety with high complication rates and it should be considered as a differential diagnosis for febrile abdominal pain syndrome in the post-abortion period. The contrast-enhanced CT or MRI have the highest sensitivity and specificity to diagnose the ovarian veins thrombi. The treatment it consists in a combination of anticoagulation therapy and antibiotics. In case that anticoagulation is contraindicated it´s recommended placing an inferior vena cava filter.
{"title":"An unusual case of acute abdomen: bilateral ovarian veins thrombophlebitis","authors":"A. Oprişan, M. Solana","doi":"10.32440/ar.2021.138.02.cc02","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.cc02","url":null,"abstract":"Postabortion ovarian vein septic thrombophlebitis is a very rare variety with high complication rates and it should be considered as a differential diagnosis for febrile abdominal pain syndrome in the post-abortion period. The contrast-enhanced CT or MRI have the highest sensitivity and specificity to diagnose the ovarian veins thrombi. The treatment it consists in a combination of anticoagulation therapy and antibiotics. In case that anticoagulation is contraindicated it´s recommended placing an inferior vena cava filter.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49598413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.ed01
A. Ortiz, M. Sánchez-Niño
{"title":"Treating anemia in chronic kidney disease. ¿An ongoing revolution?","authors":"A. Ortiz, M. Sánchez-Niño","doi":"10.32440/ar.2021.138.02.ed01","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.ed01","url":null,"abstract":"","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45811148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.rev03
Tomás Chivato Pérez
The COVID19 pandemic produced by SARSCOV2 has changed and impacted all areas of Medicine, including Allergology. Professionals and patients have seen how this virus has affected the daily routine at different levels. In this article three relevant aspects will be reviewed. First, the epidemiological, clinical, diagnostic, therapeutic and preventive measures differences between rhinitis due to SARSCOV2 infection and allergic rhinitis due to pollen sensitization are described. Second, the impact of new technologies and digital transformation on the daily routine of Allergology at the care and teaching level is reviewed. Finally, an update of the vaccines against SARSCOV2 is carried out from the point of view of safety for the allergic patient.
{"title":"Allergology and COVID19 pandemic","authors":"Tomás Chivato Pérez","doi":"10.32440/ar.2021.138.02.rev03","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.rev03","url":null,"abstract":"The COVID19 pandemic produced by SARSCOV2 has changed and impacted all areas of Medicine, including Allergology. Professionals and patients have seen how this virus has affected the daily routine at different levels. In this article three relevant aspects will be reviewed. First, the epidemiological, clinical, diagnostic, therapeutic and preventive measures differences between rhinitis due to SARSCOV2 infection and allergic rhinitis due to pollen sensitization are described. Second, the impact of new technologies and digital transformation on the daily routine of Allergology at the care and teaching level is reviewed.\u0000Finally, an update of the vaccines against SARSCOV2 is carried out from the point of view of safety for the allergic patient.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43779783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.rev05
Bibiana Lasses Martínez, Jana Dziakova, Antonio Torres
Since its first appearance in Wuhan at the end of 2019, the SARS-CoV-2 pandemic has brought serious repercussions worldwide, Spain being among the most affected countries. This health crisis resulted in the cancellation of surgeries pertaining to both malignant and benign pathologies, including bariatric and metabolic surgery. Patients with morbid obesity, besides their delay in surgical interventions, are at high risk of contracting severe COVID-19. For this reason, once the epidemiological situation has improved in our hospitals and the necessary resources become again available, this surgical activity should be progressively restarted. The goal of this paper is to review the published literature regarding the main perioperative recommendations concerning safe bariatric and metabolic surgery during the COVID-19 pandemic.
{"title":"Bariatric and metabolic surgery during the COVID-19 crisis: strategies facing two pandemics","authors":"Bibiana Lasses Martínez, Jana Dziakova, Antonio Torres","doi":"10.32440/ar.2021.138.02.rev05","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.rev05","url":null,"abstract":"Since its first appearance in Wuhan at the end of 2019, the SARS-CoV-2 pandemic has brought serious repercussions worldwide, Spain being among the most affected countries. This health crisis resulted in the cancellation of surgeries pertaining to both malignant and benign pathologies, including bariatric and metabolic surgery. Patients with morbid obesity, besides their delay in surgical interventions, are at high risk of contracting severe COVID-19. For this reason, once the epidemiological situation has improved in our hospitals and the necessary resources become again available, this surgical activity should be progressively restarted. The goal of this paper is to review the published literature regarding the main perioperative recommendations concerning safe bariatric and metabolic surgery during the COVID-19 pandemic.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41742136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.rev06
C. Jiménez, E. Moreno, A. Manrique, A. Marcacuzco, Ó. Caso, I. Justo
Pancreas transplantation (PT) is considered as the only treatment that can convert a diabetic patient in a euglucemic state without the use of insulin or oral antidiabetic drugs. From 1996 to the end of 2016, more than 50,000 PT were performed in USA, and in Spain were performed 1.730 PT during the last 10 years. In this review we will perform an update of PT considering the introduction of several advances in the last years, adding our accumulated experience from the beginning of our program in the year 1995. The first PT was carried out in the Hospital of the University of Minnesota, and from that date several significant improvements have been introduced along the time due to advances in surgical technique in pancreas donors and recipients, perioperative management of patients, and introduction of more potent immunosuppressors able to reduce the rejection rate under 20%. Although PT is a therapy associated with a higher morbidity (pancreas graft thrombosis, systemic and intraabdominal infections, anastomotic leakages, etc.), currently most of the PT teams have obtained a rate of 93% of patient survival at 3-years, and between 78% and 83% of graft survival at 3-years. Additionally, the normal pancreas graft function is associated with an improvement of quality of life and most of complications related to diabetes, without the necessity to treat with antidiabetics drugs or insulin.
{"title":"Update of pancreas transplantation. Experience of the Hospital Doce de Octubre","authors":"C. Jiménez, E. Moreno, A. Manrique, A. Marcacuzco, Ó. Caso, I. Justo","doi":"10.32440/ar.2021.138.02.rev06","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.rev06","url":null,"abstract":"Pancreas transplantation (PT) is considered as the only treatment that can convert a diabetic patient in a euglucemic state without the use of insulin or oral antidiabetic drugs. From 1996 to the end of 2016, more than 50,000 PT were performed in USA, and in Spain were performed 1.730 PT during the last 10 years. In this review we will perform an update of PT considering the introduction of several advances in the last years, adding our accumulated experience from the beginning of our program in the year 1995.\u0000The first PT was carried out in the Hospital of the University of Minnesota, and from that date several significant improvements have been introduced along the time due to advances in surgical technique in pancreas donors and recipients, perioperative management of patients, and introduction of more potent immunosuppressors able to reduce the rejection rate under 20%. Although PT is a therapy associated with a higher morbidity (pancreas graft thrombosis, systemic and intraabdominal infections, anastomotic leakages, etc.), currently most of the PT teams have obtained a rate of 93% of patient survival at 3-years, and between 78% and 83% of graft survival at 3-years.\u0000Additionally, the normal pancreas graft function is associated with an improvement of quality of life and most of complications related to diabetes, without the necessity to treat with antidiabetics drugs or insulin.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41275296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.rev07
B. Vergara, B. Herrero, L. Madero
Acute lymphoblastic leukemia (ALL) continues to be the most frequent neoplasm in childhood, with a 5-year survival rate ranging from 78 to 91%. The increase in the survival rate in the last 40 years has been 30 to 80%, with no comparable improvement in the case of relapsed or refractory ALL. It is for this very reason that there is currently research into innovative treatments, such as CAR-T cell therapy. This treatment involves the ex vivo genetic modification of the patient’s own T cells, enhancing their specificity and cytotoxicity against antigens present in the majority of blasts, such as CD19. In clinical trials carried out worldwide, positive results have been obtained in patients with refractory or relapsed ALL treated with CAR-T 19 therapy, with disease-free survival at one year in up to 50% of patients, and overall survival at one year of 76%. The first published report in Spain with respect to this treatment reproduces the results obtained in clinical trials. The results were reported in HNJS in 2020 involving 8 patients treated with CAR-T 19. Complete remission was observed in 87.5% of patients one month after infusion followed by an overall survival of 75% at the time of analysis (7.6 months mean follow-up duration across all the patients). To date, the most frequent side effects described with the use of this therapy in the short term are cytokine release syndrome and neurotoxicity. This innovative therapy, therefore, represents a paradigm shift in the survival of pediatric patients with relapsed or refractory ALL. Further studies and evidence of its effectiveness and the long-term follow-up of patients treated with this therapy are still needed, but the results to date are encouraging.
{"title":"Anti-CD19 CAR-T cell theraphy in pediatric patients with relapsed/refractory acute lymphoblastic leukemia. Experience at Hospital Infantil Universitario Niño Jesús","authors":"B. Vergara, B. Herrero, L. Madero","doi":"10.32440/ar.2021.138.02.rev07","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.rev07","url":null,"abstract":"Acute lymphoblastic leukemia (ALL) continues to be the most frequent neoplasm in childhood, with a 5-year survival rate ranging from 78 to 91%. The increase in the survival rate in the last 40 years has been 30 to 80%, with no comparable improvement in the case of relapsed or refractory ALL. It is for this very reason that there is currently research into innovative treatments, such as CAR-T cell therapy. This treatment involves the ex vivo genetic modification of the patient’s own T cells, enhancing their specificity and cytotoxicity against antigens present in the majority of blasts, such as CD19. In clinical trials carried out worldwide, positive results have been obtained in patients with refractory or relapsed ALL treated with CAR-T 19 therapy, with disease-free survival at one year in up to 50% of patients, and overall survival at one year of 76%. The first published report in Spain with respect to this treatment reproduces the results obtained in clinical trials. The results were reported in HNJS in 2020 involving 8 patients treated with CAR-T 19. Complete remission was observed in 87.5% of patients one month after infusion followed by an overall survival of 75% at the time of analysis (7.6 months mean follow-up duration across all the patients). To date, the most frequent side effects described with the use of this therapy in the short term are cytokine release syndrome and neurotoxicity. This innovative therapy, therefore, represents a paradigm shift in the survival of pediatric patients with relapsed or refractory ALL. Further studies and evidence of its effectiveness and the long-term follow-up of patients treated with this therapy are still needed, but the results to date are encouraging.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42978601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-31DOI: 10.32440/ar.2021.138.02.rev01
N. L. Rey, J. Blesa, J. Obeso
Parkinson´s disease (PD) is the second most frequent neurodegenerative disease affecting the population older than 65 years old. This incidence will greatly increase due to the progressive aging of the population in the coming years. PD diagnosis is made when there is a 50-60% dopaminergic cell loss in the substantia nigra pars compacta (SNc) and the striatal dopamine loss reaches around 70-80%, coinciding with the onset of classical parkinsonian motor signs: tremor, rigidity and slowness of movement. A significant proportion of patients present non-motor symptoms, generally associated to disfunction of non-dopaminergic regions, which can appear before, around or after diagnosis (10-15 years). Therefore, in PD both dopaminergic and non-dopaminergic groups are affected, but the motor manifestations are the main reason for consultation and causes the greatest disability for many years. There is a large heterogeneity within dopaminergic neural groups in terms of morphology, metabolism, molecular pattern, protein accumulation, inflammation levels, protein expression, etc. In this review we discuss different factors that could explain the special vulnerability of certain dopaminergic neurons in the SNc. Knowledge on the mechanisms and underlying factors of this selective vulnerability of the ventrolateral dopaminergic neuros of the SNc is essential for developing neuromodulatory and/or neuroprotective therapies, leading in turn to halt or modify the neurodegenerative process in PD.
{"title":"Determinants of selective neuronal vulnerability in Parkinson's disease","authors":"N. L. Rey, J. Blesa, J. Obeso","doi":"10.32440/ar.2021.138.02.rev01","DOIUrl":"https://doi.org/10.32440/ar.2021.138.02.rev01","url":null,"abstract":"Parkinson´s disease (PD) is the second most frequent neurodegenerative disease affecting the population older than 65 years old. This incidence will greatly increase due to the progressive aging of the population in the coming years. PD diagnosis is made when there is a 50-60% dopaminergic cell loss in the substantia nigra pars compacta (SNc) and the striatal dopamine loss reaches around 70-80%, coinciding with the onset of classical parkinsonian motor signs: tremor, rigidity and slowness of movement. A significant proportion of patients present non-motor symptoms, generally associated to disfunction of non-dopaminergic regions, which can appear before, around or after diagnosis (10-15 years). Therefore, in PD both dopaminergic and non-dopaminergic groups are affected, but the motor manifestations are the main reason for consultation and causes the greatest disability for many years.\u0000There is a large heterogeneity within dopaminergic neural groups in terms of morphology, metabolism, molecular pattern, protein accumulation, inflammation levels, protein expression, etc. In this review we discuss different factors that could explain the special vulnerability of certain dopaminergic neurons in the SNc. Knowledge on the mechanisms and underlying factors of this selective vulnerability of the ventrolateral dopaminergic neuros of the SNc is essential for developing neuromodulatory and/or neuroprotective therapies, leading in turn to halt or modify the neurodegenerative process in PD.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69671808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-30DOI: 10.32440/AR.2021.138.01.REV04
J. Montes
There is general consensus in accepting that splenic surgery may be associated with significant morbidity and mortality that appears due to an interrelation of circumstances. The most common complications of splenectomy are infectious nature with an incidence of up to 40%; among infections, in 5-7% of cases may occur the so-called overwhelming postsplenectomy infection, motivated by the loss of immune functions of the spleen. In this paper, together with a basic description of the structure and functions of the spleen, the most relevant aspects and preventive measures of this serious postsplenectomy sequel are exposed.
{"title":"Splenectomy and sepsis","authors":"J. Montes","doi":"10.32440/AR.2021.138.01.REV04","DOIUrl":"https://doi.org/10.32440/AR.2021.138.01.REV04","url":null,"abstract":"There is general consensus in accepting that splenic surgery may be associated with significant morbidity and mortality that appears due to an interrelation of circumstances. The most common complications of splenectomy are infectious nature with an incidence of up to 40%; among infections, in 5-7% of cases may occur the so-called overwhelming postsplenectomy infection, motivated by the loss of immune functions of the spleen.\u0000In this paper, together with a basic description of the structure and functions of the spleen, the most relevant aspects and preventive measures of this serious postsplenectomy sequel are exposed.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44512317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-30DOI: 10.32440/AR.2021.138.01.REV09
R. Burgos Lázaro, N. Burgos Frías, JA Blázquez González, F. Gilsanz Rodríguez, G. Téllez de Peralta, JA Rodríguez Montes
The anatomical works of Juan Valverde de Amusco History of the composition of the human body, and De humani corporis fabrica by Andrés Vesalio were the two main references for anatomists and surgeons during the Renaissance. Valverde’s work is the result of the study on the corpse. It is composed of seven books and follows a descending architectural order, from head to toe, in the same way as Vesalius’ text. Valverde was accused of plagiarizing Vesalio’s De humani corporis fabrica, the criticisms came from northern Europe -Vesalio was born in Brussels-, the arguments used were lacking in solidity and more interested than with a scientific basis. It is paradoxical to see that Valverde’s work was better known in Europe than in Spain, despite being written in Spanish. The promulgation of the Real Pragmatic by Felipe II that prohibited studying in foreign universities contributed to this ignorance.
Juan Valverde de Amusco的解剖作品《人体组成史》和Andrés Vesalio的《人体组织》是文艺复兴时期解剖学家和外科医生的两本主要参考书。巴尔韦德的作品是对尸体研究的结果。它由七本书组成，遵循从头到脚的递减建筑顺序，与维萨留斯的文本相同。Valverde被指控抄袭了Vesalio的《De humani corporatis fabrica》，批评来自北欧——Vesalio出生于布鲁塞尔——所使用的论点缺乏坚实性，比科学依据更感兴趣。尽管巴尔韦德的作品是用西班牙语写成的，但在欧洲比在西班牙更为人所知，这是自相矛盾的。费利佩二世颁布的《真正的实用主义》禁止在外国大学学习，这也助长了这种无知。
{"title":"Juan Valverde de Amusco in the medicine of the spanish Renaissance","authors":"R. Burgos Lázaro, N. Burgos Frías, JA Blázquez González, F. Gilsanz Rodríguez, G. Téllez de Peralta, JA Rodríguez Montes","doi":"10.32440/AR.2021.138.01.REV09","DOIUrl":"https://doi.org/10.32440/AR.2021.138.01.REV09","url":null,"abstract":"The anatomical works of Juan Valverde de Amusco History of the composition of the human body, and De humani corporis fabrica by Andrés Vesalio were the two main references for anatomists and surgeons during the Renaissance.\u0000Valverde’s work is the result of the study on the corpse. It is composed of seven books and follows a descending architectural order, from head to toe, in the same way as Vesalius’ text. Valverde was accused of plagiarizing Vesalio’s De humani corporis fabrica, the criticisms came from northern Europe -Vesalio was born in Brussels-, the arguments used were lacking in solidity and more interested than with a scientific basis.\u0000It is paradoxical to see that Valverde’s work was better known in Europe than in Spain, despite being written in Spanish. The promulgation of the Real Pragmatic by Felipe II that prohibited studying in foreign universities contributed to this ignorance.","PeriodicalId":75487,"journal":{"name":"Anales de la Real Academia Nacional de Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47219362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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