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Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris最新文献

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Éditorial 编辑
H. Laccourreye
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引用次数: 0
Qui suis-je ? U…
A. Werner, O. Laccourreye
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引用次数: 0
Extrusion cutanée à répétition d’un implant cochléaire 反复挤压人工耳蜗的皮肤
C. Poncet-Wallet , Y. Ormezzano , E. Ernst , C. Toffin , R. Dhote , E. Harboun-Cohen , B. Frachet

Objective

An observation of a difficult-to-diagnose complication of the cochlear implant: recurring cutaneous extrusion of a cochlear implant is reported.

Patients and methods

The history of an adult patient with total deafness is reported. She received an implant in her right ear in 1988, which was then explanted because of absence of hearing results. She received a second implant in her left ear in 2002, which was then explanted in 2007 because of cutaneous extrusion. In 2008, a second implant of a different brand was placed in her left ear, with the central part placed away from the first site, but extrusion recurred. A new attempt to encapsulate the central part with a hydroxyapatite box also ended in extrusion and was explanted in 2008.

Results

Various diagnoses to explain these cutaneous problems were suggested during this clinical progression: infection, allergy, and a reaction to a foreign body. No hypothesis could be clearly ruled out.

Conclusion

Cutaneous complications after cochlear implant are exceptional. As soon as cutaneous disorders appear, a rigorous diagnostic process must be followed so that the patient can be recommended a long-lasting solution to restore quality hearing.

目的观察人工耳蜗术后复发性皮肤挤压的并发症。患者和方法报告1例成人全聋患者的病史。1988年,她的右耳接受了人工耳蜗植入手术,后来由于听力不佳而被摘除。2002年,她在左耳接受了第二次植入手术,2007年,由于皮肤挤压,她的左耳被摘除。2008年,在她的左耳植入了第二个不同品牌的植入物,将中心部分放置在远离第一个位置的位置,但挤压复发。用羟基磷灰石盒子包裹中心部位的新尝试也以挤压告终,并于2008年进行了移植。结果在此临床进展过程中,提出了多种诊断来解释这些皮肤问题:感染、过敏和对异物的反应。没有任何假设可以被明确地排除。结论人工耳蜗术后皮肤并发症少见。一旦出现皮肤疾病,必须遵循严格的诊断过程,以便向患者推荐持久的解决方案,以恢复高质量的听力。
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引用次数: 1
Les adénocarcinomes nasosinusiens revisités. Intérêt pronostique de la classification histologique OMS 2005 鼻腺癌重访。who 2005组织学分类的预后意义
A. El Ayoubi , F. Poizat , R. Garrel , V. Costes , B. Guerrier , L. Essakalli , M. Kzadri , L. Crampette

Objectives

The WHO 2005 histological classification separates sinonasal adenocarcinoma (ADC) into three classes: intestinal-type adenocarcinoma (ITAC), low-grade sinonasal ADC and high-grade sinonasal ADC. The goal of this study was to check the relevance of this classification on the prognosis of patients treated for ADC.

Patients and methods

All the files of patients treated consecutively in the ENT department of the Montpellier University Hospital for ADC between 1980 and 2003 were retrospectively re-examined. Each case was reviewed for anatomical and pathological data based on the immunohistochemistry results according to the WHO 2005 classification, with a study of a panel of markers: cytokeratin 7 (CK7), cytokeratin 20 (CK20), Villin, CDX2 and EGFR. The epidemiologic data, the methods of treatment and the follow-up were studied. The survival probabilities were calculated using the Kaplan-Meier method and the survival graphs were compared using a log-rank test.

Results

Sixty-two files were reviewed. Twelve patients were reclassified into the adenoid cystic carcinoma category and excluded from the study. In the 50 remaining cases, there were 36 ITAC cases, four low-grade ADC cases and 10 high-grade dedifferentiated carcinomas. For all of the ADC cases, the total survival at 5 years and without recurrence was 64 and 52%, respectively. The analysis of the three subgroups showed a total survival of 72.2% for ITAC, 100% for low-grade and 20% for high-grade ADC with a significant difference (p = 0.044). This immunohistochemical distinction was mainly based on the expression of CK20 found in 98% of the ITAC cases and absent in low- and high-grade ADC patients.

Conclusion

The WHO 2005 classification for sinonasal ADC provides a valuable prognosis by showing a difference in the progression profile between ITAC, low-grade ADC and high-grade ADC. Moreover, broader studies should be conducted to investigate the different subtypes of ITAC.

目的WHO 2005将鼻窦腺癌(ADC)分为肠型腺癌(ITAC)、低分级鼻窦腺癌和高分级鼻窦腺癌。本研究的目的是检查这种分类与ADC治疗患者预后的相关性。患者与方法回顾性分析蒙彼利埃大学附属医院耳鼻喉科1980 ~ 2003年连续治疗的ADC患者资料。我们根据WHO 2005的分类,根据免疫组化结果对每个病例进行解剖和病理资料的回顾,并研究了一组标记物:细胞角蛋白7 (CK7)、细胞角蛋白20 (CK20)、绒毛蛋白、CDX2和EGFR。对流行病学资料、治疗方法及随访进行了研究。生存概率采用Kaplan-Meier法计算,生存图采用log-rank检验比较。结果共审阅了62份文件。12例患者被重新分类为腺样囊性癌,并被排除在研究之外。其余50例中,ITAC 36例,低级别ADC 4例,高级别去分化癌10例。对于所有ADC病例,5年和无复发的总生存率分别为64%和52%。三个亚组的分析显示,ITAC的总生存率为72.2%,低级别ADC为100%,高级别ADC为20%,差异有统计学意义(p = 0.044)。这种免疫组织化学区分主要基于CK20在98%的ITAC病例中的表达,而在低级别和高级别ADC患者中不存在。结论WHO 2005对鼻窦ADC的分级显示了ITAC、低级别ADC和高级别ADC的进展情况差异,提供了有价值的预后。此外,应该进行更广泛的研究来调查ITAC的不同亚型。
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引用次数: 8
Étude bactériologique des cavités d’ethmoïdectomie chez des patients ayant une polypose naso-sinusienne opérée 鼻-鼻窦息肉切除术患者民族切除术腔的细菌学研究
N. Day , J.-L. Mainardi , D. Malinvaud , P. Bonfils

Objectifs

Faire une analyse prospective de prélèvements effectués dans les cavités d’ethmoïdectomie chez des patients opérés de polypose naso-sinusienne afin de déterminer le type de flore retrouvée dans ces cavités et de corréler ces résultats avec l’état clinique des patients.

Patients et méthodes

Soixante patients consécutifs opérés d’ethmoïdectomie totale pour une polypose naso-sinusienne dans un hôpital hospitalo-universitaire ont été inclus en prospectif entre juin et novembre 2008. Pour chaque patient, deux prélèvements par écouvillon dans chaque cavité d’ethmoïdectomie ont été réalisés et mis en culture pour la recherche de bactéries aérobies et anaérobies ainsi que pour la recherche de champignons. Une étude de la sensibilité aux antibiotiques a été réalisée sur toutes les souches bactériennes isolées.

Résultats

Quarante-huit patients (80 %) avaient des germes pathogènes, essentiellement un Staphylococcus aureus (60 % des patients) ou un bacille à Gram négatif. Les microorganismes étaient dans l’ensemble sensibles aux antibiotiques, en particulier aux aminosides. Enfin, il n’existait pas de lien significatif entre l’état clinique et la présence de bactéries pathogènes.

Conclusion

Dans cette étude, un nombre important de patients sont colonisés avec des germes pathogènes. La présence de germes pathogènes n’est pas corrélée avec l’état clinique des patients.

Objective

To compare the bacteriological and clinical findings in ethmoid specimens from patients with nasal polyposis after radical ethmoidal surgery.

Patients and methods

From June to November 2008, 60 patients were prospectively included. For each patient, two samples for each ethmoidal cavity were taken. Aerobic and anaerobic bacterial cultures and fungal cultures were processed and the antibiotic susceptibility was evaluated for each isolated bacterial strain.

Results

Pathogenic bacteria were isolated in 48 patients (80%) including predominantly Staphylococcus aureus (60%) or a Gram-negative bacterium. The microorganisms were nearly all susceptible to antibiotics, including the aminoglycosides. No correlation between the presence of pathogenic bacteria and the clinical status of the patients was found.

Conclusion

In this study, a great number of patients was colonized with pathogenic bacteria. However, the presence of pathogenic bacteria was not correlated with the clinical status of the patients.

目的对鼻鼻窦炎手术患者的民族切开术腔标本进行前瞻性分析,以确定这些腔中发现的菌群类型,并将这些结果与患者的临床状况联系起来。患者和方法在2008年6月至11月期间,在一所大学医院连续60例鼻-鼻窦息肉切除术患者被纳入前瞻性研究。对于每个患者,用棉絮从每个民族切除术腔中提取两份样本,并培养好氧和厌氧细菌以及真菌。对所有分离菌株进行抗生素敏感性研究。结果48例患者(80%)为致病菌,主要为金黄色葡萄球菌(60%)或革兰氏阴性杆菌。微生物一般对抗生素敏感,特别是对氨基糖苷。最后,临床状况与致病菌的存在没有显著关系。结论在本研究中,大量患者感染致病菌。致病菌的存在与患者的临床状况无关。目的:比较根治性ethmoidal手术后鼻息肉患者ethmoid标本的细菌学和临床发现。患者和方法2008年6月至11月,预计纳入60例患者。对于每个患者,取两个ethmoidal腔样本。对各分离菌株的好氧和厌氧细菌培养和真菌培养进行了处理,并评价了抗生素敏感性。结果48例患者(80%)分离出致病细菌,主要为金黄色葡萄球菌(60%)或革兰氏阴性细菌。= =地理= =根据美国人口普查,这个县的面积为,其中土地和(1.1%)水。相关between the presence of No pathogenic细菌and the clinical status of the was找到病人。本研究的结论是,大量患者感染了致病性细菌。然而,致病性细菌的存在与患者的临床状况不相关。
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引用次数: 14
Voie d’abord transorale et cervicale sans mandibulotomie dans les cancers de l’oropharynx avec réparation par lambeau libre fasciocutané antébrachial 口咽癌经口和颈椎无下颌骨切开术,臂前束膜自由修补
A. Bozec , G. Poissonnet , E. Chamorey , A. Sudaka , C. Laout , J. Vallicioni , F. Demard , O. Dassonville

Objective

To evaluate the role of a combined transoral and cervical approach without mandibulotomy for surgery of oropharyngeal cancer with fasciocutaneous radial forearm free flap reconstruction.

Material and methods

All patients who underwent this type of surgery between 2003 and 2007 were included in this retrospective study. We analyzed postoperative outcomes, surgical margins (histological study) and the oncological and functional results.

Results

A total of 24 patients were included in this study. There was no free flap failure. Surgical margins were negative for 23 of the 24 patients. At 3 years, overall, cause-specific, and disease-free survival rates were 73, 76 and 68%, respectively. A good functional result (normal or slightly impaired function) was obtained for oral diet, speech, mouth opening and esthetic outcome in 78, 82, 92 and 86% of the patients, respectively.

Conclusion

This double surgical approach without mandibulotomy in selective cases can replace the transmandibular approach in locally advanced oropharyngeal cancer surgery.

目的探讨经口经颈联合入路不切除下颌骨在口咽癌桡骨前臂游离皮瓣重建中的应用价值。材料和方法本回顾性研究包括2003年至2007年间所有接受此类手术的患者。我们分析了术后结果、手术切缘(组织学研究)以及肿瘤和功能结果。结果本研究共纳入24例患者。没有自由皮瓣失效。24例患者中有23例手术切缘阴性。3年时,总生存率、病因特异性生存率和无病生存率分别为73%、76%和68%。在口腔饮食、言语、开口和审美方面,分别有78%、82%、92%和86%的患者获得了良好的功能结果(正常或轻微受损)。结论在局部晚期口咽癌手术中,选择性不切除下颌骨的双手术入路可替代经下颌骨入路。
{"title":"Voie d’abord transorale et cervicale sans mandibulotomie dans les cancers de l’oropharynx avec réparation par lambeau libre fasciocutané antébrachial","authors":"A. Bozec ,&nbsp;G. Poissonnet ,&nbsp;E. Chamorey ,&nbsp;A. Sudaka ,&nbsp;C. Laout ,&nbsp;J. Vallicioni ,&nbsp;F. Demard ,&nbsp;O. Dassonville","doi":"10.1016/j.aorl.2009.06.002","DOIUrl":"10.1016/j.aorl.2009.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the role of a combined transoral and cervical approach without mandibulotomy for surgery of oropharyngeal cancer with fasciocutaneous radial forearm free flap reconstruction.</p></div><div><h3>Material and methods</h3><p>All patients who underwent this type of surgery between 2003 and 2007 were included in this retrospective study. We analyzed postoperative outcomes, surgical margins (histological study) and the oncological and functional results.</p></div><div><h3>Results</h3><p>A total of 24 patients were included in this study. There was no free flap failure. Surgical margins were negative for 23 of the 24 patients. At 3 years, overall, cause-specific, and disease-free survival rates were 73, 76 and 68%, respectively. A good functional result (normal or slightly impaired function) was obtained for oral diet, speech, mouth opening and esthetic outcome in 78, 82, 92 and 86% of the patients, respectively.</p></div><div><h3>Conclusion</h3><p>This double surgical approach without mandibulotomy in selective cases can replace the transmandibular approach in locally advanced oropharyngeal cancer surgery.</p></div>","PeriodicalId":75509,"journal":{"name":"Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris","volume":"126 4","pages":"Pages 182-189"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aorl.2009.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28299978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Mastoïdite aiguë extériorisée chez l’enfant : la mastoïdectomie peut-elle être évitée ? 儿童急性外部性乳腺炎:是否可以避免乳腺切除术?
J.-P. Trijolet , D. Bakhos , P. Lanotte , S. Pondaven , E. Lescanne

Objective

Mastoidectomy is the standard management for exteriorized mastoiditis. The objective of this study was to assess the results of conservative management of acute mastoiditis and to study the types of bacteria isolated and their sensitivity to antibiotics.

Methods

A retrospective study including children admitted with acute mastoiditis was conducted between 1994 and 2007. Intravenous antibiotics were systematic. Since 2002, mastoidectomy has been replaced by retroauricular puncture and grommet tube insertion.

Results

Forty-four children had acute mastoiditis. All but one (temporozygomatic swelling) had postauricular swelling. The culture was positive in 78% of cases. Streptococcus pneumoniae was the most common bacteria identified. Twenty-six subperiosteal abscesses were found on the CT scan. Mastoidectomy was performed in 17 cases, 16 of which took place before 2002. The hospital stay has been decreased by six days with retroauricular puncture and grommet tube insertion management.

Conclusion

In the absence of intracranial complications and suspicion of Fusobacterium necrophorum, a retroauricular puncture and grommet tube insertion associated with antibiotic therapy is an effective alternative to mastoidectomy in the treatment of acute mastoiditis with subperiosteal abscess.

目的:乳突切除术是外露性乳突炎的标准治疗方法。本研究的目的是评估保守治疗急性乳突炎的结果,并研究分离的细菌类型及其对抗生素的敏感性。方法对1994 ~ 2007年收治的急性乳突炎患儿进行回顾性研究。系统地静脉注射抗生素。自2002年以来,乳突切除术已被耳后穿刺和套管插入所取代。结果44例患儿发生急性乳突炎。除一例颞颧肿胀外,其余均有耳后肿胀。78%的病例培养阳性。肺炎链球菌是最常见的细菌。CT扫描发现26个骨膜下脓肿。17例行乳突切除术,其中16例于2002年以前手术。通过耳后穿刺和套管插入管理,住院时间减少了6天。结论在无颅内并发症和怀疑有坏死梭杆菌的情况下,耳后穿刺置管联合抗生素治疗乳突切除术是治疗急性乳突炎骨膜下脓肿的有效方法。
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引用次数: 12
Qui suis-je ? T… 我是谁?T ...
A. Werner, O. Laccourreye
{"title":"Qui suis-je ? T…","authors":"A. Werner,&nbsp;O. Laccourreye","doi":"10.1016/j.aorl.2009.02.006","DOIUrl":"10.1016/j.aorl.2009.02.006","url":null,"abstract":"","PeriodicalId":75509,"journal":{"name":"Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris","volume":"126 4","pages":"Pages 236-237"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aorl.2009.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28445275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancers de l’hypopharynx T1-T2 « N0 » traités par chirurgie exclusive. Étude GETTEC 下咽T1-T2“N0”癌经专项手术治疗。GETTEC研究
M. Foucher , G. Poissonnet , J.-P. Rame , B. Toussaint , P.-O. Védrine , O. Dassonville , D. de Raucourt , A. Cosmidis

Objective

Consider whether surgery alone in the treatment of early cancers of the hypopharynx can give identical or better results in terms of survival and local control than radiotherapy.

Methods

Forty-five patients were operated on during the years 1991–2004. Surgical treatment consisted in a resection by the transoral approach in four patients and 41 patients had a partial pharyngolaryngectomy. An elective neck dissection was performed on 43 patients.

Results

The 1-, 3-, and 5-year overall survival rates were 100, 95, and 75%. The 1-, 3-, and 5-year locoregional control rates were 93, 88, and 82% and were influenced by the presence of dysplasia on surgical margins (p = 0.027). The oncological occurrences observed were five local recurrences, two nodal recurrences, ten second primary cancers, and two metastases. Five locoregional failures out of seven were controlled after a second treatment.

Conclusion

Surgery alone gives completely satisfactory results in terms of survival and locoregional control. In case of recurrence, this makes it possible to operate on patients in nonirradiated areas with lower morbidity and mortality and better results. These results must be confirmed by a randomized trial.

目的探讨单纯手术治疗早期下咽癌在生存和局部控制方面是否能获得与放疗相同或更好的结果。方法对我院1991 ~ 2004年收治的45例患者进行手术治疗。手术治疗包括4例经口入路切除,41例部分咽喉切除术。43例患者行择期颈部清扫术。结果1、3、5年总生存率分别为100%、95%、75%。1年、3年和5年的局部控制率分别为93%、88%和82%,并受到手术边缘发育不良的影响(p = 0.027)。观察到的肿瘤发生为5例局部复发,2例淋巴结复发,10例第二原发癌和2例转移。在第二次治疗后,7例局部失败中有5例得到了控制。结论单纯手术治疗在生存和局部控制方面完全令人满意。在复发的情况下,这使得可以在未照射区域对患者进行手术,发病率和死亡率较低,效果较好。这些结果必须通过随机试验来证实。
{"title":"Cancers de l’hypopharynx T1-T2 « N0 » traités par chirurgie exclusive. Étude GETTEC","authors":"M. Foucher ,&nbsp;G. Poissonnet ,&nbsp;J.-P. Rame ,&nbsp;B. Toussaint ,&nbsp;P.-O. Védrine ,&nbsp;O. Dassonville ,&nbsp;D. de Raucourt ,&nbsp;A. Cosmidis","doi":"10.1016/j.aorl.2009.06.006","DOIUrl":"10.1016/j.aorl.2009.06.006","url":null,"abstract":"<div><h3>Objective</h3><p>Consider whether surgery alone in the treatment of early cancers of the hypopharynx can give identical or better results in terms of survival and local control than radiotherapy.</p></div><div><h3>Methods</h3><p>Forty-five patients were operated on during the years 1991–2004. Surgical treatment consisted in a resection by the transoral approach in four patients and 41 patients had a partial pharyngolaryngectomy. An elective neck dissection was performed on 43 patients.</p></div><div><h3>Results</h3><p>The 1-, 3-, and 5-year overall survival rates were 100, 95, and 75%. The 1-, 3-, and 5-year locoregional control rates were 93, 88, and 82% and were influenced by the presence of dysplasia on surgical margins (<em>p</em> <!-->=<!--> <!-->0.027). The oncological occurrences observed were five local recurrences, two nodal recurrences, ten second primary cancers, and two metastases. Five locoregional failures out of seven were controlled after a second treatment.</p></div><div><h3>Conclusion</h3><p>Surgery alone gives completely satisfactory results in terms of survival and locoregional control. In case of recurrence, this makes it possible to operate on patients in nonirradiated areas with lower morbidity and mortality and better results. These results must be confirmed by a randomized trial.</p></div>","PeriodicalId":75509,"journal":{"name":"Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris","volume":"126 4","pages":"Pages 203-207"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aorl.2009.06.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40008099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Lambeaux libres et reconstruction en carcinologie cervicofaciale : état des lieux après 20 ans 颈面癌的游离碎片与重建:20年后的现状
F. Kolb
{"title":"Lambeaux libres et reconstruction en carcinologie cervicofaciale : état des lieux après 20 ans","authors":"F. Kolb","doi":"10.1016/j.aorl.2009.03.008","DOIUrl":"10.1016/j.aorl.2009.03.008","url":null,"abstract":"","PeriodicalId":75509,"journal":{"name":"Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris","volume":"126 4","pages":"Pages 226-235"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aorl.2009.03.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28461644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
期刊
Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris
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