Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris最新文献

Objectives

To report the known data on the functional consequences of cochlear ischemia and the tools available to detect them.

Methods

Review of the main integrated in vivo models described in mammals.

Results

The main integrated models of cochlear ischemia use laser doppler velocimetry to measure the degree of ischemia. Cochlear function can be effectively monitored during cochlear ischemia through the cochlear potentials and otoacoustic emissions, each of these signals giving specific information. The cochlea appears to be particularly resistant to several minutes of reversible ischemia. Indirect monitoring of cochlear ischemia can be achieved through distortion-product otoacoustic emissions during surgical procedures to the cerebellopontine angle. It is still impossible to directly and noninvasively detect cochlear ischemia in nonsurgical clinical practice.

Conclusions

Integrated models of cochlear ischemia have contributed greatly to our knowledge of the functional behavior of the cochlea in this specific situation. Clinical practice now needs to be able to detect cochlear ischemia early and noninvasively, for example in cases of sudden hearing loss.

Introduction

Head and neck sarcomas comprise a heterogeneous and biologically diverse set of rare neoplasms. The difficulty treating the disease requires multidisciplinary consultation to improve outcome. In an effort to clarify the clinical behavior of head and neck sarcomas and evaluate treatment, we present our experience and review the relevant literature.

Patients and methods

This is a retrospective analysis of 15 patients with histologically proven head and neck sarcoma treated in the ENT department between 1998 and 2007. All cases were confirmed by histologic exam with immunohistochemical analysis.

Results

Nine women and six men were included in the study. The mean age was 38.4 years (range: 6–73 years). Computed tomography and MRI were done in 66.7% and 60% of the patients, respectively, to evaluate tumor extension. Metastases were demonstrated in three cases. Curative treatment in eight cases was based on different combinations of chemotherapy, radiotherapy, and surgery. Complete remission was obtained in eight cases. Local recurrence was noted in two cases. Two patients died from tumor metastasis. Two patients were lost to follow-up.

Conclusion

Head and neck sarcomas present diverse rare neoplasms. They make up 5%–20% of all soft tissue sarcomas. All age groups can be affected by this neoplasm, with no predominance in one sex or the other. The most common histologic type is rhabdomyosarcoma, especially in children. Because of the potential for systemic metastasis, extension must be assessed. Treatment is based essentially on the association of surgery, radiotherapy, and chemotherapy to optimize therapeutic results. Five-year survival varies between 44% and 80%.

Objectives

Retropharyngeal lymph node metastasis from papillary thyroid carcinoma is uncommon. Traditional extirpative procedures include cervical, cervical-parotid, and transmandibular approaches. The authors report the case of a patient with a retropharyngeal node metastasis originating from papillary carcinoma of the thyroid gland that was successfully removed by a transoral approach.

Method

A 49-year-old man presented for removal of a retropharyngeal lymph node metastasis measuring 21 mm × 27 mm from papillary thyroid carcinoma. Surgical excision was performed through a transoral approach using a surgical navigation system to assess the location of the node precisely.

Result

The postoperative course was uneventful with return to a normal diet on the first postoperative day and hospital discharge on the second postoperative day. Three months after surgery, TSH-stimulated thyroglobulin was undetectable.

Conclusion

The transoral approach to retropharyngeal space is a reliable procedure with low morbidity compared to other approaches. The limited surgical access provided by this approach should limit its use to removal of well-circumscribed lesions not invading adjacent structures.

Objectives

To determine the value of technetium-99 m bone scintigraphy in the screening of bone metastases in the systematic initial extension assessment of upper aerodigestive tract suamous cell carcinomas; to identify risk factors of these bone metastases for better screening.

Material and methods

In this prospective study, the initial assessment of tumoral extension was systematically associated with bone scintigraphy. Only patients with no malignant tumors were included in the study. Any skeletal fixation identified was then analyzed with standard radiography and/or tomodensitometry and with the patient's clinical progression to confirm whether or not the fixation was metastatic. The sensitivity and specificity of bone scintigraphy was then calculated. A correlation between bone pain or hypercalcemia and confirmed bone metastases was also systematically sought to determine whether these factors were predictive of bone metastases so as to better target the screening.

Results

Among the 55 patients included in the study, three had confirmed bone metastases. All were detected by the bone scintigraphy, with a sensitivity of 100%. However, the 20 false-positive results gave a low specificity of 62%. Bone pain was described by two patients, but they were among the three metastatic patients. Specificity was 100%, but the sensitivity was only 67%. Three patients had hypercalcemia: the three metastatic patients. The sensitivity and specificity were 100%. In the tumoral status of the three patients with bone metastasis, tumors were small, classified as T1 or T2, but with substantial node involvement, classified N3, and with invasion of the internal jugular vein in two cases.

Conclusion

The incidence of bone metastases in the initial extension assessment was low; consequently, they are not sought systematically. However, their presence radically changes the prognosis and the therapeutic management, raising the question of screening. The technetium-99 m bone scintigraphy has limits, with many false-positive resulting the need for additional investigations. Defining the risk factors for bone metastases would improve screening. Two questions remain: what factors are involved? The bone pain and the hypercalcemia must be analyzed with a larger number of cases, but they seem to be nonspecific. The node involvement stage could be a more reliable parameter, in particular in cases of jugular vein invasion; what method should be used? In the future, the PET scan could be the key procedure not only in the locoregional extension assessment, but also for general extensions, in a single procedure investigating the whole body.

Today vestibular rehabilitation has an important place in managing chronic vertigo and balance disorders. It is based on the principle of completing and/or accelerating the physiological processes of central compensation when, for one reason or another, these processes cannot be put in place to offset a vestibular deficit. From a practical point of view, this compensation uses and reinforces the compensatory strategies that are activated spontaneously, but incompletely, by the patient, i.e., adaptation, substitution, and habituation strategies. These techniques call on physical exercises and/or instrumental techniques that should be adapted to the patient based on the clinical workup and paraclinical instrumental assessment done by a trained specialist, which will identify side involved, the central or peripheral character of the disorder, the current degree of central compensation, and the patient's ability to use various sensory inputs. In addition to the acute vestibular deficits, the best indications are chronic dizziness stemming from unilateral or bilateral peripheral vestibular deficit, or a nonprogressive central but stabilized deficit, with incomplete compensation, whatever the patient's age. Measures should be applied to the disorder as the patient describes it, with the number of sessions specified.

Objectives

To report anatomic and physiologic characteristics of the tympanic membrane, to discuss the etiology and pathogenesis of tympanic perforation, and to discuss its management.

Material and methods

After a review of the literature, different surgical techniques and the postoperative results were evaluated.

Results

The rate of tympanic membrane closure is greater than 90% for the majority of authors. Age, mucosa inflammation, pathological contralateral ear (perforation, otitis media, cholesteatoma), and surgical experience influence this result.

Discussion

Even if surgical results are good, abstention must always be proposed and all complications must be explained.

Conclusion

Palisade cartilage tympanoplasty is an effective technique for both tympanic membrane closures.

Tonsillectomy may be performed as an outpatient procedure because post-tonsillectomy hemorrhages occur during the first few hours, and therefore are diagnosed before discharge, or occur after the sixth day. Nevertheless, not all patients are eligible for outpatient tonsillectomy. Both the ENT surgeon and the anesthesiologist must identify children who cannot be operated as outpatients because they do not satisfy the social criteria for discharge on the day of surgery (their parents do not speak French, they live too far from the hospital, etc.) or because they have individual risk factors for complications unrelated to their tonsils, such as bleeding disorders or related to their tonsils, such as a history of obstructive sleep apnea due to enlarged tonsils, particularly for young children. The anesthetic protocol must minimize the risk of postoperative nausea and vomiting. After tonsillectomy, the child may be discharged from the recovery room if he is fully awake, with no dyspnea and no oral bleeding, and is able to swallow liquids, without repeated vomiting.