Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_12
P G Satyaswaroop, E Gurpide
{"title":"Metabolism and secretion of androgens by rat seminiferous tubules: tracer superfusion studies.","authors":"P G Satyaswaroop, E Gurpide","doi":"10.1007/978-1-4613-4440-7_12","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_12","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"165-9"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_19
E M Wilson, A A Smith
{"title":"Localization of androgen receptors in rat testis: biochemical studies.","authors":"E M Wilson, A A Smith","doi":"10.1007/978-1-4613-4440-7_19","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_19","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"281-6"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_22
M Sar, W E Stumpf, W S McLean, A A Smith, V Hansson, S N Nayfeh, F S French
{"title":"Localization of androgen target cells in the rat testis: autoradiographic studies.","authors":"M Sar, W E Stumpf, W S McLean, A A Smith, V Hansson, S N Nayfeh, F S French","doi":"10.1007/978-1-4613-4440-7_22","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_22","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"311-9"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_3
J H Dorrington, I B Fritz
{"title":"Androgen synthesis and metabolism by preparations from the seminiferous tubule of the rat testis.","authors":"J H Dorrington, I B Fritz","doi":"10.1007/978-1-4613-4440-7_3","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_3","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"37-52"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_23
V Hansson, S C Weddington, O Naess, A Attramadal, F S French, N Kotite, S N Nayfeh
Using ABP as an index of Sertoli cell secretory function, several important features of the Sertoli cell have emerged: 1. The stimulation of ABP production by FSH clearly points to the Sertoli cell as a target cell for FSH (3,4,9-16,21,24). 2. The dramatic effects of androgens on ABP production both in immature and mature rats also suggest that the Sertoli cell is a target cell for androgen (3,12,14,16,25). 3. The striking reduction in ABP production in the cryptorchid testis raises the question whether impairment of Sertoli cell function is the primary reason for the loss of germ cells that occurs in this condition (20). 4. Drugs like nitrofurazone or ethionine, or X-irradiation only slightly affect the secretory function of the Sertoli cells (ABP production), indicating that these treatments most probably have direct effects on the germ cells as well. Thus, measurement of ABP production rate is a very important tool in order to evaluate how hormones, drugs and physical injuries might affect the secretory function of the Sertoli cell. This test system might be of great use in order to study the physiology and hormonal regulation of the Sertoli cells. It might also be valuable in pharmacological and toxicological studies.
{"title":"Testicular androgen binding protein (ABP) - a parameter of Sertoli cell secretory function.","authors":"V Hansson, S C Weddington, O Naess, A Attramadal, F S French, N Kotite, S N Nayfeh","doi":"10.1007/978-1-4613-4440-7_23","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_23","url":null,"abstract":"<p><p>Using ABP as an index of Sertoli cell secretory function, several important features of the Sertoli cell have emerged: 1. The stimulation of ABP production by FSH clearly points to the Sertoli cell as a target cell for FSH (3,4,9-16,21,24). 2. The dramatic effects of androgens on ABP production both in immature and mature rats also suggest that the Sertoli cell is a target cell for androgen (3,12,14,16,25). 3. The striking reduction in ABP production in the cryptorchid testis raises the question whether impairment of Sertoli cell function is the primary reason for the loss of germ cells that occurs in this condition (20). 4. Drugs like nitrofurazone or ethionine, or X-irradiation only slightly affect the secretory function of the Sertoli cells (ABP production), indicating that these treatments most probably have direct effects on the germ cells as well. Thus, measurement of ABP production rate is a very important tool in order to evaluate how hormones, drugs and physical injuries might affect the secretory function of the Sertoli cell. This test system might be of great use in order to study the physiology and hormonal regulation of the Sertoli cells. It might also be valuable in pharmacological and toxicological studies.</p>","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"323-36"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11241153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_26
I B Fritz, B G Louis, P S Tung, M Griswold, F G Rommerts, J H Dorrington
{"title":"Biochemical responses of cultured Sertoli cell-enriched preparations to follicle stimulating hormone and dibutyryl cyclic AMP.","authors":"I B Fritz, B G Louis, P S Tung, M Griswold, F G Rommerts, J H Dorrington","doi":"10.1007/978-1-4613-4440-7_26","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_26","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"367-82"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11411699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_27
A R Means, D J Tindall
{"title":"FSH-induction of androgen binding protein in testes of Sertoli cell-only rats.","authors":"A R Means, D J Tindall","doi":"10.1007/978-1-4613-4440-7_27","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_27","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"383-98"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11411700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_9
B i Tamaoki, H Inano, K Suzuki
{"title":"Testicular enzymes related to steroid metabolism.","authors":"B i Tamaoki, H Inano, K Suzuki","doi":"10.1007/978-1-4613-4440-7_9","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_9","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"123-32"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7
M. Dufau, V. Hansson, Martin Ritzén, Richard Sherins
{"title":"Hormonal Regulation of Spermatogenesis","authors":"M. Dufau, V. Hansson, Martin Ritzén, Richard Sherins","doi":"10.1007/978-1-4613-4440-7","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77069501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1975-01-01DOI: 10.1007/978-1-4613-4440-7_14
A Bartke, M E Harris, J K Voglmayr
{"title":"Regulation of testosterone and dihydrotestosterone levels in rete testis fluid. Evidence for androgen biosynthesis in seminiferous tubules in vivo.","authors":"A Bartke, M E Harris, J K Voglmayr","doi":"10.1007/978-1-4613-4440-7_14","DOIUrl":"https://doi.org/10.1007/978-1-4613-4440-7_14","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"2 ","pages":"197-212"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4613-4440-7_14","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12412686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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