Jugoslavenska ginekologija i opstetricija最新文献

The authors followed up a pregnant woman with Addison's disease. Prior to, and throughout pregnancy, she received hydrocortisone in daily doses of 20 mg. The basic disease did not deteriorate during pregnancy. The pregnancy was terminated in the 41st week of gestation by induced labour. The infant's birth weight was below the 10th centile for the gestational age. Apgar score was 6. During the puerperium, the maternal basic disease got worse, requiring the increased substitution therapy. Both the mother and child discharged in good condition, on the 11th postpartal day.

The authors describe an extremely rare combination of simultaneous intrauterine and interstitial pregnancy. In spite of the rupture of interstitial pregnancy in the 13th week and cornual resection, it was possible to restrain the intrauterine pregnancy under careful control until the 38th week, when a healthy mature baby was delivered by elective Caesarian section. The cicatrix of the uterus after cornual resection held the pregnancy well. Severe anaemia as a consequence of the bleeding before and during operation was quickly corrected and did not harm the further development of the child.

The value of prospective cytologic diagnosis in cervical intraepithelial neoplasia (CIN) is analysed by means of ROC (receiver operating characteristic) curves. Examined was a group of 160 women with subsequent cone biopsies. The result of a prospective cytologic diagnosis in moderate dysplasia, severe dysplasia and carcinoma in situ is analysed separately, taking into consideration the particular frequencies in the studied group. The most reliable prospective cytologic diagnosis is in moderate dysplasia, followed by carcinoma in situ a slightly more reliable prospective diagnosis than that in severe dysplasia.

About each tenth woman having been confined in Valjevo's hospital was controlled at the Prenatal Guidance Unit of the Hospital's Maternity Ward. Out of the women controlled at the hospital, 2.5% had pre-term deliveries, while this percentage in other women having been controlled at the hospital's guidance unit.

From 1961-1978, 218 patients with the carcinoma of the corpus uteri were treated in the hospital of Maribor . They were on average 60 years old. In most of the cases (87%) the disease was classified as stage I. Only the operation was performed in 15.6% of the patients, only radiation in 11.5%, and in the rest of patients a combined therapy was used. The patients survived a 5-year period in 75%; the best prognosis was observed in stage I a-84%.

There are presented two cases of clear cell carcinoma of the endometrium. In one 63-years old, was stage II, and in the second, 49-years old, stage I. Both were treated with surgery and actinotherapy. The first woman from them live 8 years without tumour, and the second 7 months.

Eisenmenger's syndrome is one of the congenital heart defects which deteriorates in the course of pregnancy. For this reason, it is tried to discourage the patient from becoming pregnant, or to strictly interrupt pregnancy up to the 10th gestation week, or -- if the former proves impossible -- to introduce intensive medical supervision until the end of gravidity. A delivery is described of a 23-year old woman, in whom, when 19 years old, Eisenmenger's syndrome -- developed secondarily on the atrial septal defect -- was diagnosed by catheterization. She was admitted to the Department in the 26th week of pregnancy and as successfully confined in the 38th week by using vacuum extraction. Peripartal antibiotic prophylaxis was applied during labour, although she was given oxygen. No derivatives of ergotamine were administered in order to avoid undesirable effects. The loss of blood was controlled and replaced. She was discharged with a healthy girl on the 9th postpartal day without any complications.

The musculature of the isthmic and ampullar segment of the human oviduct reacts to Prostaglandin F-2 alpha by the increased tonus. The tonus increased was more pronounced in the musculature of the gravid oviduct. Prostaglandin F-2 alpha in the presence of Indomethacin products a significantly lower tonus increase of the musculature of the isthmic and ampullar segment of the non-gravid human oviduct than is the case when applied alone.

The study aimed at determining the frequency of latent herpes virus hominis type 1 infection in healthy parturients. The infection can be detected only by the presence of anti herpes virus hominis type 1 antibodies in their blood. To this end 102 blood samples of both parturients and the umbilical cord were concurrently analysed by the complement fixation test. The mean geometrical antibody titer value in mothers was 13.968. More than 90% of the parturients examined had anti HVH type 1 antibodies in their blood. Out of 102 pairs (mother--umbilical cord) of blood samples, in 34 (33.34%) the observed anti HVH type 1 antibody titer was the same in the parturients' blood and in the umbilical cord blood, while in 62 samples (60.78%) the titer of these antibodies was twice as high in the umbilical cord blood than in the parturients. It appears that this transplacental transfer of anti HVH type 1 antibodies plays a significant role in the protection of the newborn against generalized HVH infection, although this kind of protection is limited in its duration and not so efficacious as cell-induced immunity.