Platelets are known to have a role major in the pathogenesis of atherothrombosis. More giant and hyperreactive platelets accelerate the formation of an intracoronary thrombus. An increased MPV as an indicator of larger and more reactive platelets represents a risk factor for overall vascular mortality, including myocardial infarction. This study aimed to identify the increase of Mean Platelet Volume in Patients with Acute Coronary Syndromes, especially in ST-elevation myocardial infarction and Non-ST-elevation myocardial infarction. Thus this parameter can be used as consideration for diagnosis and treatment decisions. This research is an analytic observational with a cross-sectional method. The subjects were patients with STEMI and NSTEMI who were hospitalized in ICCU Dr.Sardjito Hospital Yogyakarta. Thirty-four subjects STEMI and NSTEMI patients at Dr. Sardjito Hospital, consisting of 28 males (82,35%) and six women (17,65%) with a mean age of 55,5 ± 10,3 years. The results showed that MPV in AMI was higher in patients with STEMI than NSTEMI, but this difference is not significant (p = 0,091). This study concludes that MPV to be higher in patients with STEMI compared to NSTEMI. MPV may be used as a marker of myocardial infarction in clinically appropriate situations.
{"title":"Increased Mean Platelet Volume (MPV) in Patients with ST Elevation Myocardial Infarction (STEMI) Compared to Non-ST Elevation Myocardial Infarction (NSTEMI) Patients","authors":"Tri Ratnaningsih, I. Istiqomah","doi":"10.31964/mltj.v6i2.320","DOIUrl":"https://doi.org/10.31964/mltj.v6i2.320","url":null,"abstract":"Platelets are known to have a role major in the pathogenesis of atherothrombosis. More giant and hyperreactive platelets accelerate the formation of an intracoronary thrombus. An increased MPV as an indicator of larger and more reactive platelets represents a risk factor for overall vascular mortality, including myocardial infarction. This study aimed to identify the increase of Mean Platelet Volume in Patients with Acute Coronary Syndromes, especially in ST-elevation myocardial infarction and Non-ST-elevation myocardial infarction. Thus this parameter can be used as consideration for diagnosis and treatment decisions. This research is an analytic observational with a cross-sectional method. The subjects were patients with STEMI and NSTEMI who were hospitalized in ICCU Dr.Sardjito Hospital Yogyakarta. Thirty-four subjects STEMI and NSTEMI patients at Dr. Sardjito Hospital, consisting of 28 males (82,35%) and six women (17,65%) with a mean age of 55,5 ± 10,3 years. The results showed that MPV in AMI was higher in patients with STEMI than NSTEMI, but this difference is not significant (p = 0,091). This study concludes that MPV to be higher in patients with STEMI compared to NSTEMI. MPV may be used as a marker of myocardial infarction in clinically appropriate situations.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"6 1","pages":"145-151"},"PeriodicalIF":0.0,"publicationDate":"2020-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45961603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toxoplasmosis, despite its mild course in immunocompetent individuals, it may have a more severe course in immunosuppressed patients such as hematology and oncology patients. This study aimed to contribute to the importance of that issue by evaluating the seropositivity rates of Toxoplasma gondii (T. gondii) in Hematology and Oncology patients and sharing the data obtained. Serum samples sent from pediatric and adult Hematology/Oncology outpatient clinic to the Microbiology Laboratory between January 2017 and August 2019 were analysed using Architect Toxo IgG and IgM Reagent Kit with chemiluminescent microparticular enzyme immunoassay method on Architect system. A total of 673 patient samples belonging to 131 pediatric patients and 542 adult patients were analysed in the study. Median age of the study group was 29 (range: 0 - 83) and 53.5% of them were male. While T. gondii IgM positivity was 8% IgG positivity was 28.7%. T. gondii IgG seropositivities in male and female patients were 27.2% and 30.4% respectively (p = 0.44). T. gondii IgM seropositivities in pediatric and adult patients were 6.9% and 8.3% respectively and IgG seropositivities were 24.4% and 29.7% (p = 0.78 and p = 0.46 respectively). T. gondii IgM positivity was found as 8% and IgG positivity as 28.7% in the study group. In conclusion, data obtained from the study were in compliance with both domestic and foreign data and the highest rate of IgM and IgG seropositivity was found in patients with lymphoma.
{"title":"Evaluation of Toxoplasma gondii IgM and IgG Seropositivities in Serum Samples Sent from Pediatric and Adult Hematology/Oncology Outpatient Clinics","authors":"A. Bakır, M. Guney","doi":"10.31964/mltj.v6i2.342","DOIUrl":"https://doi.org/10.31964/mltj.v6i2.342","url":null,"abstract":"Toxoplasmosis, despite its mild course in immunocompetent individuals, it may have a more severe course in immunosuppressed patients such as hematology and oncology patients. This study aimed to contribute to the importance of that issue by evaluating the seropositivity rates of Toxoplasma gondii (T. gondii) in Hematology and Oncology patients and sharing the data obtained. \u0000Serum samples sent from pediatric and adult Hematology/Oncology outpatient clinic to the Microbiology Laboratory between January 2017 and August 2019 were analysed using Architect Toxo IgG and IgM Reagent Kit with chemiluminescent microparticular enzyme immunoassay method on Architect system. \u0000A total of 673 patient samples belonging to 131 pediatric patients and 542 adult patients were analysed in the study. Median age of the study group was 29 (range: 0 - 83) and 53.5% of them were male. While T. gondii IgM positivity was 8% IgG positivity was 28.7%. T. gondii IgG seropositivities in male and female patients were 27.2% and 30.4% respectively (p = 0.44). T. gondii IgM seropositivities in pediatric and adult patients were 6.9% and 8.3% respectively and IgG seropositivities were 24.4% and 29.7% (p = 0.78 and p = 0.46 respectively). T. gondii IgM positivity was found as 8% and IgG positivity as 28.7% in the study group. In conclusion, data obtained from the study were in compliance with both domestic and foreign data and the highest rate of IgM and IgG seropositivity was found in patients with lymphoma.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"6 1","pages":"163-171"},"PeriodicalIF":0.0,"publicationDate":"2020-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44884589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-29DOI: 10.31964/MLTJ.V3I2.134.G67
Rifqoh Mukhtar Mayasin, Wahdah Norsiah
Pediculosis capitis or head lice infestation caused by Pediculus humanus var. capitis. Its caused irritation and scalp pruritus. Its occurs most commonly in children becaused they couldn’t keep their personal hygiene independently. Pediculosis capitis caused disconcentrated, lack of sleep, parental anxiety, social embarrassment and isolation. The objective of this study was to determine the correlation between Pediculosis capitis with personal hygiene in rural primary schoolchildren in Cempaka Village, Banjarbaru Municipality. This analytic observational case control study design, at first determined 33 (19,87%) schoolchildren was infested pediculosis capitis from 166 population. Other 33 schoolchildren randomized uninfested pediculosis capitis as the controls group (1:1 to case group). Pediculosis capitis was known by identified head lice, nymph or eggs of Pediculus humanus var. capitis and personal hygiene was measured by questionnaire. Chi Square test result, there was significant moderate positive correlation between pediculosis capitis with personal hygiene (p value <0.001 and r = 0,516). Improved hair hygiene and avoid shared private tool like comb or other hair accesories as strategies for effective control pediculosis were recommended.
{"title":"Pediculosis Capitis dan Personal Hygiene pada Anak SD di Daerah Pedesaan Kotamadya Banjarbaru","authors":"Rifqoh Mukhtar Mayasin, Wahdah Norsiah","doi":"10.31964/MLTJ.V3I2.134.G67","DOIUrl":"https://doi.org/10.31964/MLTJ.V3I2.134.G67","url":null,"abstract":"Pediculosis capitis or head lice infestation caused by Pediculus humanus var. capitis. Its caused irritation and scalp pruritus. Its occurs most commonly in children becaused they couldn’t keep their personal hygiene independently. Pediculosis capitis caused disconcentrated, lack of sleep, parental anxiety, social embarrassment and isolation. The objective of this study was to determine the correlation between Pediculosis capitis with personal hygiene in rural primary schoolchildren in Cempaka Village, Banjarbaru Municipality. This analytic observational case control study design, at first determined 33 (19,87%) schoolchildren was infested pediculosis capitis from 166 population. Other 33 schoolchildren randomized uninfested pediculosis capitis as the controls group (1:1 to case group). Pediculosis capitis was known by identified head lice, nymph or eggs of Pediculus humanus var. capitis and personal hygiene was measured by questionnaire. Chi Square test result, there was significant moderate positive correlation between pediculosis capitis with personal hygiene (p value <0.001 and r = 0,516). Improved hair hygiene and avoid shared private tool like comb or other hair accesories as strategies for effective control pediculosis were recommended.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"58-62"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42586562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jatropha curcas twigs are part of the Jatropha curcas which can be utilized as herbal treatment by the community to overcome the vaginal discharge problem. Vaginal discharge is a common symptom experienced by most women caused by Candida albicans infection. This research used the true experiment with posttest only control design which aimed to know the content of phytochemistry and antifungal potential of Jatropha curcas twigs extract on Candida albicans growth. Extract of Jatropha curcas in this study was obtained through a solvent extraction process using ethanol 96% by the method of maceration. The method used for the phytochemistry test was a qualitative method, while for the antifungal potential test was done by diffusion method with the concentration of 10%, 25%, 30%, 40% and 50%. The results of Phytochemistry test showed that Jatropha curcas twigs extracts are saponins, tannins, and flavonoids, but no alkaloid compounds were found, however a test result of the antifungal potential test showed that the average diameter of inhibition zone of Candida albicans growth is 0 mm. The conclusion of this study is Jatropha curcas twigs extracts can not inhibit Candida albicans growth, For other researchers which use jatropha curcas twigs, are suggested to do a phytochemical test quantitatively and to test the antifungal potential with dilution method.
{"title":"Potensi Antifungi Tangkai Daun Jarak Pagar Terhadap Pertumbuhan Candida albicans","authors":"N.M.Y. Wiratni, I. N. Jirna, I. S. Dhyanaputri","doi":"10.31964/MLTJ.V3I2.169","DOIUrl":"https://doi.org/10.31964/MLTJ.V3I2.169","url":null,"abstract":"Jatropha curcas twigs are part of the Jatropha curcas which can be utilized as herbal treatment by the community to overcome the vaginal discharge problem. Vaginal discharge is a common symptom experienced by most women caused by Candida albicans infection. This research used the true experiment with posttest only control design which aimed to know the content of phytochemistry and antifungal potential of Jatropha curcas twigs extract on Candida albicans growth. Extract of Jatropha curcas in this study was obtained through a solvent extraction process using ethanol 96% by the method of maceration. The method used for the phytochemistry test was a qualitative method, while for the antifungal potential test was done by diffusion method with the concentration of 10%, 25%, 30%, 40% and 50%. The results of Phytochemistry test showed that Jatropha curcas twigs extracts are saponins, tannins, and flavonoids, but no alkaloid compounds were found, however a test result of the antifungal potential test showed that the average diameter of inhibition zone of Candida albicans growth is 0 mm. The conclusion of this study is Jatropha curcas twigs extracts can not inhibit Candida albicans growth, For other researchers which use jatropha curcas twigs, are suggested to do a phytochemical test quantitatively and to test the antifungal potential with dilution method.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48139262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In a laboratory, an erythrocyte is done by using hemocytometer and microscope. The task is to measure and assess the size and shape of the erythrocyte. But this procedure is time consuming, complex and tedious. As a solution to this problem, to provide an automated, cost-effective and efficient alternative to detection and counting of erythrocyte, hematology analyzers are used. However, false results related either to erythrocyte or other parameters from complete blood count may be observed in several instances. The objective study was to compare the accuracy of erythrocyte count results of automatic hematological analysis by the manual method. The study is an analytic survey with a cross-sectional design. Erythrocyte counting is done by using three types of control blood, namely high, normal and low, with 9 repetitions. In high control blood, the mean erythrocytes count by the manual method was 7.08 million/μl with a bias value of 1.4%, while that by the automated method was 7.03 million/μl with a bias value of 0.7%. The mean erythrocyte count in normal control blood by the manual method was 4.50 million/μl with a bias value of 0.9%, while that by the automated method was 4.4 million/μl with a bias value of 2.4%. And in low control blood, the mean erythrocyte count by the manual method was 1.72 million/μl with 4.4% bias value, while that the automated method was 1.67 million/μl with 1.2% bias value. Statistical analysis showed no significant difference in accuracy between the erythrocyte count of manual methods with automated methods.
{"title":"Akurasi Hitung Jumlah Eritrosit Metode Manual dan Metode Otomatis","authors":"Neni Oktiyani, fahriyan fahriyan, A. Muhlisin","doi":"10.31964/mltj.v3i2.166","DOIUrl":"https://doi.org/10.31964/mltj.v3i2.166","url":null,"abstract":"In a laboratory, an erythrocyte is done by using hemocytometer and microscope. The task is to measure and assess the size and shape of the erythrocyte. But this procedure is time consuming, complex and tedious. As a solution to this problem, to provide an automated, cost-effective and efficient alternative to detection and counting of erythrocyte, hematology analyzers are used. However, false results related either to erythrocyte or other parameters from complete blood count may be observed in several instances. The objective study was to compare the accuracy of erythrocyte count results of automatic hematological analysis by the manual method. The study is an analytic survey with a cross-sectional design. Erythrocyte counting is done by using three types of control blood, namely high, normal and low, with 9 repetitions. In high control blood, the mean erythrocytes count by the manual method was 7.08 million/μl with a bias value of 1.4%, while that by the automated method was 7.03 million/μl with a bias value of 0.7%. The mean erythrocyte count in normal control blood by the manual method was 4.50 million/μl with a bias value of 0.9%, while that by the automated method was 4.4 million/μl with a bias value of 2.4%. And in low control blood, the mean erythrocyte count by the manual method was 1.72 million/μl with 4.4% bias value, while that the automated method was 1.67 million/μl with 1.2% bias value. Statistical analysis showed no significant difference in accuracy between the erythrocyte count of manual methods with automated methods.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44050017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Currently, many brands and types of skin whitening cosmetics can be found on the market. Not all products are safe for consumers. Illegal or non-licensed cosmetics from BPOM are suspect because unlisted cosmetics tend to contain harmful chemicals such as mercury (Hg). Mercury (Hg) was including harmful heavy metals. The use of mercury has been banned since 1998 through PERMENKES RI No. 445 of 1998, where mercury in small concentrations can be toxic. Negative effects of mercury such as allergies, skin irritation and permanent damage to the nervous system, kidney, brain and disrupt the development of the fetus, especially when used in high doses. The aim of this study was to know whether there is mercury content on bleach mask that sold in Martapura market in March 2017. This study used a descriptive method and the sample was taken by purposive sampling technique. There were 10 samples of face bleach mask that cost around Rp5.000,00 - Rp20.000,00. Based on the results of 10 samples taken at Martapura market, 3 samples contained mercury of face bleach mask. The conclusion of this study is that mercury still used as bleach on the facial in the Martapura market. Therefore, BPOM needs more supervision and intensive counseling about the risk of bleaching cosmetics containing mercury, so the consumer can be careful in choosing cosmetics.
{"title":"Logam Merkuri pada Masker Pemutih Wajah di Pasar Martapura","authors":"Dinna Rakhmina, Lisa Lisa, Jasmadi Joko Kartiko","doi":"10.31964/mltj.v3i2.172","DOIUrl":"https://doi.org/10.31964/mltj.v3i2.172","url":null,"abstract":"Currently, many brands and types of skin whitening cosmetics can be found on the market. Not all products are safe for consumers. Illegal or non-licensed cosmetics from BPOM are suspect because unlisted cosmetics tend to contain harmful chemicals such as mercury (Hg). Mercury (Hg) was including harmful heavy metals. The use of mercury has been banned since 1998 through PERMENKES RI No. 445 of 1998, where mercury in small concentrations can be toxic. Negative effects of mercury such as allergies, skin irritation and permanent damage to the nervous system, kidney, brain and disrupt the development of the fetus, especially when used in high doses. The aim of this study was to know whether there is mercury content on bleach mask that sold in Martapura market in March 2017. This study used a descriptive method and the sample was taken by purposive sampling technique. There were 10 samples of face bleach mask that cost around Rp5.000,00 - Rp20.000,00. Based on the results of 10 samples taken at Martapura market, 3 samples contained mercury of face bleach mask. The conclusion of this study is that mercury still used as bleach on the facial in the Martapura market. Therefore, BPOM needs more supervision and intensive counseling about the risk of bleaching cosmetics containing mercury, so the consumer can be careful in choosing cosmetics.","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"53-57"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48133994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alde Fajar Pambudi, Subrata Tri Widada, B. Setiawan
Lipemic serum caused by lipoprotein particles such as chylomicrons, VLDL (Very Low-Density Lipoprotein) and triglycerides. This situation causes interference chromophoric photometric analysis, interference on the wavelength and light scattering caused by the presence of lipid particles. This study aims to determine and differences glucose levels in lipemic serum with and without the addition of gamma-cyclodextrin incubation temperature 23oC. The study's pre-experimental use research design static group comparison. The samples were all lipemic serum many as 20 samples. The research findings were the glucose levels without adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 267,19 mg/dl. Whereas the glucose levels with adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 169,23 mg/dl. The difference of glucose levels with or without adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 97,96 mg/dl(35,23%).
{"title":"Serum Lipemik dengan Flokulan Gamma-Siklodekstrin pada Pemeriksaan Glukosa","authors":"Alde Fajar Pambudi, Subrata Tri Widada, B. Setiawan","doi":"10.31964/mltj.v3i2.165","DOIUrl":"https://doi.org/10.31964/mltj.v3i2.165","url":null,"abstract":"Lipemic serum caused by lipoprotein particles such as chylomicrons, VLDL (Very Low-Density Lipoprotein) and triglycerides. This situation causes interference chromophoric photometric analysis, interference on the wavelength and light scattering caused by the presence of lipid particles. This study aims to determine and differences glucose levels in lipemic serum with and without the addition of gamma-cyclodextrin incubation temperature 23oC. The study's pre-experimental use research design static group comparison. The samples were all lipemic serum many as 20 samples. The research findings were the glucose levels without adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 267,19 mg/dl. Whereas the glucose levels with adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 169,23 mg/dl. The difference of glucose levels with or without adding the flocculant Gamma-cyclodextrin incubation temperature 23oC was 97,96 mg/dl(35,23%).","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47033627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anny Thuraidah, Rima Agnes Widya Astuti, Dinna Rakhmina
Tuberculosis is an infectious disease due to Mycobacterium tuberculosis germ that can infect several organs, including the lungs, kidneys, and bones. The goal of treatment of tuberculosis is tuberculosis bacilli destroy quickly and prevent recurrence. First category treatment of tuberculosis is isoniazid, rifampin, streptomycin, ethambutol, and pyrazinamide. Although the most anti-tuberculosis drug is acceptable in therapy, but have potentially toxic effects hematologic reactions such as agranulocytosis, eosinophilia, thrombocytopenia, and anemia. This research aims to know the correlation between anti-tuberculosis drug consumption in pulmonary TB patients against anemia. Method of this research was Analytical Survey with a Cross-Sectional design. The average results of red blood cell count for 0 months 5,16 106/uL, 2 months 4,39 106/uL and 6 months 4,61 106/uL, haemoglobin levels for 0 month 15,17 g/dL, 2 months 12,73 g/dL and 6 months 13,28 g/dL as well as hematocrit value for 0 month 44,26 %, 2 months 38,24 % and 6 months 39,04 %. From Spearman statistics analytical was obtained significant of red blood cell count 0.004 < α (0.05), levels of hemoglobin 0.007 < α (0.05) and the value of hematocrit 0.015 < α (0.05), it was concluded there was correlation between long consumption of anti-tuberculosis drug with anemia and the value of the correlation coefficient count of red blood cells -0.531, levels of hemoglobin-0.479 as well as the value of hematocrit -0.440 means has the power correlations are medium. Further research is recommended to use different parameters such as the number of platelets, AST/ALT levels and should use the same patient sample or from 0 months up to 6 months
{"title":"Anemia dan Lama Konsumsi Obat Anti Tuberculosis","authors":"Anny Thuraidah, Rima Agnes Widya Astuti, Dinna Rakhmina","doi":"10.31964/MLTJ.V3I2.157","DOIUrl":"https://doi.org/10.31964/MLTJ.V3I2.157","url":null,"abstract":"Tuberculosis is an infectious disease due to Mycobacterium tuberculosis germ that can infect several organs, including the lungs, kidneys, and bones. The goal of treatment of tuberculosis is tuberculosis bacilli destroy quickly and prevent recurrence. First category treatment of tuberculosis is isoniazid, rifampin, streptomycin, ethambutol, and pyrazinamide. Although the most anti-tuberculosis drug is acceptable in therapy, but have potentially toxic effects hematologic reactions such as agranulocytosis, eosinophilia, thrombocytopenia, and anemia. This research aims to know the correlation between anti-tuberculosis drug consumption in pulmonary TB patients against anemia. Method of this research was Analytical Survey with a Cross-Sectional design. The average results of red blood cell count for 0 months 5,16 106/uL, 2 months 4,39 106/uL and 6 months 4,61 106/uL, haemoglobin levels for 0 month 15,17 g/dL, 2 months 12,73 g/dL and 6 months 13,28 g/dL as well as hematocrit value for 0 month 44,26 %, 2 months 38,24 % and 6 months 39,04 %. From Spearman statistics analytical was obtained significant of red blood cell count 0.004 < α (0.05), levels of hemoglobin 0.007 < α (0.05) and the value of hematocrit 0.015 < α (0.05), it was concluded there was correlation between long consumption of anti-tuberculosis drug with anemia and the value of the correlation coefficient count of red blood cells -0.531, levels of hemoglobin-0.479 as well as the value of hematocrit -0.440 means has the power correlations are medium. Further research is recommended to use different parameters such as the number of platelets, AST/ALT levels and should use the same patient sample or from 0 months up to 6 months","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"42-46"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48320382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A kelepon seller is one of the groups susceptible to metal pollution from motor vehicle emissions from the tetraethyl-Pb and tetramethyl-Pb combustion products that are always added to motor vehicle fuel. Lead metal has a negative impact on the environment including human health. The first effect of chronic Pb poisoning before reaching the target organ is the presence of hemoglobin synthesis disorder so that the hemoglobin level decreases.The effect of lead poisoning in the blood can occur if the Pb content is more 70 ug/dl or 0.7 ppm which will lead to anemia. This study aims to determine a level of lead metal in the blood of kelepon seller that exceeds the threshold. Descriptive survey research method with cross-sectional design on the sample from 15 respondents. The lead metal (Pb) in the blood is measured using an Atomic Absorption Spectrophotometer (SSA) device. The result of the research shows that there are 13 respondents (86,7%) whose Pb metal content exceeds the blood lead threshold that is 20 ug / dL or 0,20 ppm. The highest level of lead in the blood of the respondents was 0.73 ppm and the lowest was 0.10 ppm. Two respondents with lead in blood less than 0.20 ppm are known to always use personal protective equipment while working, even though the working time is 6-10 hours/day. It is advisable to conduct further research by examining Hb levels and abnormalities of erythrocytes in the blood of the kelepon seller and conducting similar research
{"title":"Kadar Logam Timbal (Pb) dalam Darah Penjual Klepon","authors":"Yayuk Kustiningsih, Noni Fitriyanti, Nurlailah Nurlailah","doi":"10.31964/MLTJ.V3I2.168","DOIUrl":"https://doi.org/10.31964/MLTJ.V3I2.168","url":null,"abstract":"A kelepon seller is one of the groups susceptible to metal pollution from motor vehicle emissions from the tetraethyl-Pb and tetramethyl-Pb combustion products that are always added to motor vehicle fuel. Lead metal has a negative impact on the environment including human health. The first effect of chronic Pb poisoning before reaching the target organ is the presence of hemoglobin synthesis disorder so that the hemoglobin level decreases.The effect of lead poisoning in the blood can occur if the Pb content is more 70 ug/dl or 0.7 ppm which will lead to anemia. This study aims to determine a level of lead metal in the blood of kelepon seller that exceeds the threshold. Descriptive survey research method with cross-sectional design on the sample from 15 respondents. The lead metal (Pb) in the blood is measured using an Atomic Absorption Spectrophotometer (SSA) device. The result of the research shows that there are 13 respondents (86,7%) whose Pb metal content exceeds the blood lead threshold that is 20 ug / dL or 0,20 ppm. The highest level of lead in the blood of the respondents was 0.73 ppm and the lowest was 0.10 ppm. Two respondents with lead in blood less than 0.20 ppm are known to always use personal protective equipment while working, even though the working time is 6-10 hours/day. It is advisable to conduct further research by examining Hb levels and abnormalities of erythrocytes in the blood of the kelepon seller and conducting similar research","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"47-52"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49510751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
One of the food hygiene and sanitation efforts that must be implemented by the Nutrition Installation is to maintain the hygiene quality of tableware consider the equipment as a source of food contaminants. The purpose of this research was to know the effectiveness of washing the tableware method to decrease the bacterial number. The research method uses true experimental design. The research design used was posttest only control group design and sampling technique was simple random. Instruments in the research is a set of tools for experiment, sampling, and examination. The independent variable in this research is washing method on the tableware using method A, B, and C while the dependent variable is the number of a bacteria of tableware. The results showed that the number of tableware bacteria in Sambang Lihum Psychiatric Hospital exceeded of the standard/not qualified, except on washing method A which fulfilled the requirement that is under 100 colony/cm2 of tool surface. The conclusion of this research is there is a significant difference to the three washing methods which is shown with the p-value of 0,027. Need to do further research on the washing process by adding sterilization process
{"title":"Angka Kuman pada Beberapa Metode Pencucian Peralatan Makan","authors":"Brilian Rizky Ananda, Laily Khairiyati","doi":"10.31964/mltj.v3i1.153","DOIUrl":"https://doi.org/10.31964/mltj.v3i1.153","url":null,"abstract":"One of the food hygiene and sanitation efforts that must be implemented by the Nutrition Installation is to maintain the hygiene quality of tableware consider the equipment as a source of food contaminants. The purpose of this research was to know the effectiveness of washing the tableware method to decrease the bacterial number. The research method uses true experimental design. The research design used was posttest only control group design and sampling technique was simple random. Instruments in the research is a set of tools for experiment, sampling, and examination. The independent variable in this research is washing method on the tableware using method A, B, and C while the dependent variable is the number of a bacteria of tableware. The results showed that the number of tableware bacteria in Sambang Lihum Psychiatric Hospital exceeded of the standard/not qualified, except on washing method A which fulfilled the requirement that is under 100 colony/cm2 of tool surface. The conclusion of this research is there is a significant difference to the three washing methods which is shown with the p-value of 0,027. Need to do further research on the washing process by adding sterilization process","PeriodicalId":76135,"journal":{"name":"Medical laboratory technology","volume":"3 1","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2017-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49162079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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