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A novel technique for safe blind percutaneous tracheotomy: retrospective case-series study on three hundred eighty-six patients 一种安全的经皮盲气管切开术新技术:386例回顾性病例系列研究
Q4 ANESTHESIOLOGY Pub Date : 2023-11-10 DOI: 10.1186/s42077-023-00388-6
Bassem N. Beshay, Islam M. Elbardan, Moustafa A. Moustafa, Ahmed S. Shehab
Abstract Background Griggs’ technique with assisting tools for bedside percutaneous tracheotomy (PDT) is safe and fast and carries few complications in expert hands. Assisting tools are not routinely available in many ICUs. The study aims to evaluate the impact of a novel technique for blind percutaneous tracheotomy on success rate, duration of the procedure, and rate of complications. This retrospective case-series study was conducted in the different intensive care units in Alexandria University Hospitals. Three hundred eighty-six patients were recruited from 1 January 2018 to 31 December 2021. After skin incision and blunt pre-tracheal dissection, a needle was inserted to access the airway, transfixing the endotracheal tube (ETT). A change in the alignment of the needle tip inside the trachea from caudal to cranial accompanied the withdrawal of the ETT off the trachea. In situ caudal needle redirection for subsequent guidewire passage distally into the trachea was done. The rest of the procedure was continued as Griggs’ technique. Results The success rate was 100%. The procedure duration (in seconds) was 125.73±19.52. No procedure-related deaths or major intra-operative complications were encountered. Only three patients developed pneumothorax and subcutaneous emphysema, managed by intercostal tube insertion. Conclusions The novel technique for blind percutaneous tracheotomy was successful with no significant procedure-related complications. The duration of the procedure was comparable to the literature.
背景Griggs技术配合辅助工具行床边经皮气管切开术(PDT)安全、快速,在专家手中并发症少。辅助工具在许多icu中并不常见。本研究旨在评估盲经皮气管切开术的新技术对成功率、手术时间和并发症发生率的影响。这项回顾性病例系列研究是在亚历山大大学医院的不同重症监护室进行的。从2018年1月1日至2021年12月31日招募了386名患者。在皮肤切开和钝性气管前剥离后,插入一根针进入气道,穿刺气管内管(ETT)。气管内针尖从尾端到颅端方向的改变伴随着气管内气管内气管内气管内气管内插管的取出。原位尾端针重定向,随后导丝通过远端进入气管。接下来的手术仍沿用格里格斯的技术。结果手术成功率100%。手术时间(秒)为125.73±19.52。未发生手术相关死亡或重大术中并发症。只有3例患者发生气胸和皮下肺气肿,经肋间插管治疗。结论盲经皮气管切开术成功,无明显手术并发症。该过程的持续时间与文献相当。
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引用次数: 0
Clinical efficacy of local infiltration of lidocaine and tranexamic acid application in tonsillar region on postoperative pain and bleeding during tonsillectomy: prospective, randomized, double-blind controlled study 扁桃体局部浸润利多卡因和氨甲环酸应用对扁桃体切除术术后疼痛和出血的临床疗效:前瞻性、随机、双盲对照研究
Q4 ANESTHESIOLOGY Pub Date : 2023-11-09 DOI: 10.1186/s42077-023-00391-x
Mohamed Abdelgawad Abdelhalim Aboelsuod, Abdalla Mohamed Abdalla, Ismail Mohamed Abdelgawad Ahmed, Sameh Hamdy Seyam, Ahmed Mohamed Hassan
Abstract Background Anesthetic techniques are designed to minimize intraoperative surgical bed bleeding which is a major problem that may interfere with precision, surgery duration, or postoperative wound healing. The main reason for reoperation and/or mortality in children who have had tonsillectomies is post-tonsillectomy hemorrhage. We evaluate the local application effect of tranexamic acid and lidocaine local infiltration in the tonsillar bed during tonsillectomy surgery on postoperative analgesia and bleeding. Results FLACC scores showed a statistically significant reduction in the first 24 h in group T ( P < 0.05). Post-tonsillectomy hemorrhage was significantly minimized in group T. No complications were recorded following the local application of tranexamic acid and local lidocaine infiltration inside the tonsil bed. Conclusions Local infiltration of lidocaine provides adequate postoperative analgesia, and tranexamic acid application during tonsillectomy surgery minimizes postoperative bleeding and shortens surgery duration. Trial registration This study was preregistered with the Clinical Trials Registry (NCT05817474).
麻醉技术的目的是尽量减少术中床出血,这是一个可能影响手术精度、手术时间或术后伤口愈合的主要问题。扁桃体切除术后出血是儿童再次手术和/或死亡的主要原因。我们评价扁桃体切除术时扁桃体床局部浸润应用氨甲环酸和利多卡因对术后镇痛和出血的影响。结果T组FLACC评分在治疗前24 h显著降低(P <0.05)。t组扁桃体切除术后出血明显减少,局部应用氨甲环酸及扁桃体床内局部浸润利多卡因无并发症记录。结论局部浸润利多卡因可提供足够的术后镇痛,在扁桃体切除术中应用氨甲环酸可减少术后出血,缩短手术时间。本研究已在临床试验注册中心(NCT05817474)进行预注册。
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引用次数: 0
Evaluation of adding magnesium sulphate to intrathecal bupivacaine in lower limb orthopedic surgery 硫酸镁加入鞘内布比卡因在下肢骨科手术中的应用评价
Q4 ANESTHESIOLOGY Pub Date : 2023-11-09 DOI: 10.1186/s42077-023-00389-5
Nilesh M. Solanki, Maulik P. Bhimani, Nirmal S. Mistry, Diya Rajan
Abstract Background A subarachnoid block is the cheaper and widely used regional block for lower limb surgery. Postoperative pain occurs after lower limb orthopedic surgery from moderate to severe. We conducted a prospective, randomized, double-blind controlled trial. All patients were assessed for onset and duration of sensory and motor block, total duration of analgesia, and postoperative pain relief. This study was conducted to evaluate the efficacy of intrathecal bupivacaine with magnesium undergoing lower limb orthopedic surgery. Results One hundred patients were randomly divided into two equal groups. Group M: Intrathecal 3 ml (15 mg) of 0.5% bupivacaine + 0.2 ml (50 mg) of preservative-free 25% of magnesium sulphate. Group B: Intrathecal 3 ml (15 mg) of 0.5% bupivacaine + 0.2 ml preservative-free 0.9% normal saline. The mean time that occurred for the sensory blockade at T10 was 2.49 ± 0.49 min in group B, while it was 4.13 ± 0.74 min in group BM ( p value < 0.0001). The mean of the total duration of the sensory block in group B was 139.5 ± 32.01 min, while it was 366.4 ± 30.12 min in group BM ( p value < 0.0001). The time taken for the onset of motor block in group B was 5.28 ± 1.31 min, while it was 7.86 ± 1.19 min in group BM ( p value < 0.0001). The mean total duration of the motor block in group B was 136.3 ± 8.19 min, while it was 336.5 ± 37.08 min in group BM ( p value < 0.0001). The total duration of analgesia in group B was 141.4 ± 14.85 min, while it was 365.9 ± 44.91 min in group BM ( p value < 0.0001). The mean dose required for rescue analgesia in group B was 2.2 ± 1.14, while in group BM was 1.28 ± 0.96 ( p value < 0.0001). Conclusions The addition of 50 mg magnesium sulphate in intrathecal hyperbaric bupivacaine significantly prolongs the extended duration of sensory, motor blockade, and total duration of analgesia for patients undergoing lower limb orthopedic surgery.
摘要背景:蛛网膜下腔阻滞是一种廉价且广泛应用于下肢手术的区域阻滞。下肢骨科手术后疼痛由中度到重度不等。我们进行了一项前瞻性、随机、双盲对照试验。评估所有患者感觉和运动阻滞的发生和持续时间,镇痛总持续时间和术后疼痛缓解。本研究旨在评估布比卡因加镁鞘内注射在下肢骨科手术中的疗效。结果100例患者随机分为两组。M组:鞘内注射0.5%布比卡因3ml (15mg) +不含防腐剂的25%硫酸镁0.2 ml (50mg)。B组:鞘内注射0.5%布比卡因3 ml (15 mg) +不含防腐剂的0.9%生理盐水0.2 ml。T10时感觉阻滞发生的平均时间B组为2.49±0.49 min, BM组为4.13±0.74 min (p值<0.0001)。B组感觉阻滞总持续时间平均为139.5±32.01 min, BM组为366.4±30.12 min (p值<0.0001)。B组运动阻滞发生时间为5.28±1.31 min, BM组为7.86±1.19 min (p值<0.0001)。B组运动阻滞的平均总持续时间为136.3±8.19 min, BM组为336.5±37.08 min (p值<0.0001)。B组总镇痛时间为141.4±14.85 min, BM组总镇痛时间为365.9±44.91 min (p值<0.0001)。B组抢救镇痛所需平均剂量为2.2±1.14,BM组为1.28±0.96 (p值<0.0001)。结论布比卡因鞘内高压注入硫酸镁50 mg可显著延长下肢骨科手术患者的感觉、运动阻滞时间和总镇痛时间。
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引用次数: 0
Comparison of dose–response to two different doses of intravenous lidocaine for analgesia in patients undergoing elective laparoscopic cholecystectomy under general anesthesia 选择性腹腔镜胆囊切除术全麻下静脉注射两种不同剂量利多卡因镇痛的剂量反应比较
Q4 ANESTHESIOLOGY Pub Date : 2023-11-08 DOI: 10.1186/s42077-023-00390-y
Sunana Gupta, Prerna Attal, Nandita Mehta, Heena Saini, Sitikantha Banerjee
Abstract Background Various studies have demonstrated the analgesic benefit of systemic lidocaine in the perioperative setting, especially during laparoscopic abdominal surgery. However, the best appropriate dose for an administered bolus and continuous infusion of lignocaine is unclear. Our aim is to compare the effect of two different doses of intravenous lidocaine for analgesia in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. Fifty-four patients of ASA PS I or II, aged between 18 and 65 years undergoing elective laparoscopic cholecystectomy under general anesthesia were randomly divided into two groups of 26 patients each. Patients in group A received an intravenous bolus injection of lidocaine 1.5 mg/kg slowly over 10 min, prior to induction and then followed by a continuous infusion at the rate of 1.5 mg/kg/h via infusion pump whereas group B patients received intravenous lidocaine bolus of 1.5 mg/kg slowly over 10 min followed by infusion at the rate of 2 mg/kg/h. Postoperative analgesia was assessed by VAS score, time to first analgesic dose, and total consumption of rescue analgesic in 24 h. Results There was a statistically significant difference in mean VAS Scores between the two groups at different time intervals postoperatively. Time to first rescue analgesia was earlier in group A (30.65 min) compared to group B (49.42 min) and the difference was statistically significant. Total consumption of rescue analgesic was higher in group A with a mean of 178.85 mg compared to 126.92 mg in group B. Conclusion Both the infusion doses of Lidocaine provided clinically adequate analgesia postoperatively but the infusion dose of 2 mg/kg/h had a mean VAS score significantly lower than 1.5 mg/kg/h.
各种研究已经证明全身利多卡因在围手术期的镇痛作用,特别是在腹腔镜腹部手术中。然而,给药和持续输注利多卡因的最佳适当剂量尚不清楚。我们的目的是比较两种不同剂量的静脉利多卡因在全麻下择期腹腔镜胆囊切除术患者的镇痛效果。选择54例ASA PS I或II级患者,年龄18 ~ 65岁,在全麻下行选择性腹腔镜胆囊切除术,随机分为两组,每组26例。A组患者在诱导前先静脉滴注利多卡因1.5 mg/kg,缓慢注射10 min,然后通过输注泵以1.5 mg/kg/h的速度持续输注;B组患者静脉滴注利多卡因1.5 mg/kg,缓慢注射10 min,然后以2 mg/kg/h的速度持续输注。通过VAS评分、第一次给药时间、24 h抢救镇痛药总消耗来评价两组患者术后镇痛效果。结果两组患者术后不同时间间隔VAS评分平均值比较,差异均有统计学意义。A组第一次抢救镇痛时间(30.65 min)早于B组(49.42 min),差异有统计学意义。A组抢救镇痛药总用量平均为178.85 mg,高于b组126.92 mg。结论利多卡因输注剂量均能提供临床足够的术后镇痛,但输注剂量为2 mg/kg/h时VAS评分均显著低于1.5 mg/kg/h。
{"title":"Comparison of dose–response to two different doses of intravenous lidocaine for analgesia in patients undergoing elective laparoscopic cholecystectomy under general anesthesia","authors":"Sunana Gupta, Prerna Attal, Nandita Mehta, Heena Saini, Sitikantha Banerjee","doi":"10.1186/s42077-023-00390-y","DOIUrl":"https://doi.org/10.1186/s42077-023-00390-y","url":null,"abstract":"Abstract Background Various studies have demonstrated the analgesic benefit of systemic lidocaine in the perioperative setting, especially during laparoscopic abdominal surgery. However, the best appropriate dose for an administered bolus and continuous infusion of lignocaine is unclear. Our aim is to compare the effect of two different doses of intravenous lidocaine for analgesia in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. Fifty-four patients of ASA PS I or II, aged between 18 and 65 years undergoing elective laparoscopic cholecystectomy under general anesthesia were randomly divided into two groups of 26 patients each. Patients in group A received an intravenous bolus injection of lidocaine 1.5 mg/kg slowly over 10 min, prior to induction and then followed by a continuous infusion at the rate of 1.5 mg/kg/h via infusion pump whereas group B patients received intravenous lidocaine bolus of 1.5 mg/kg slowly over 10 min followed by infusion at the rate of 2 mg/kg/h. Postoperative analgesia was assessed by VAS score, time to first analgesic dose, and total consumption of rescue analgesic in 24 h. Results There was a statistically significant difference in mean VAS Scores between the two groups at different time intervals postoperatively. Time to first rescue analgesia was earlier in group A (30.65 min) compared to group B (49.42 min) and the difference was statistically significant. Total consumption of rescue analgesic was higher in group A with a mean of 178.85 mg compared to 126.92 mg in group B. Conclusion Both the infusion doses of Lidocaine provided clinically adequate analgesia postoperatively but the infusion dose of 2 mg/kg/h had a mean VAS score significantly lower than 1.5 mg/kg/h.","PeriodicalId":7686,"journal":{"name":"Ain-Shams Journal of Anesthesiology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135342361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malposition of right internal jugular vein cannulation into left brachiocephalic vein 右颈内静脉与左头臂静脉插管位置错误
Q4 ANESTHESIOLOGY Pub Date : 2023-11-07 DOI: 10.1186/s42077-023-00386-8
G. Sanjeev, D. Subha, D. Divya
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引用次数: 0
Awake self-proning for COVID-19 non-intubated patients—a single-centered experience COVID-19非插管患者的清醒自我防备——单一中心体验
Q4 ANESTHESIOLOGY Pub Date : 2023-11-06 DOI: 10.1186/s42077-023-00387-7
Rekha Nileshbhai Solanki, Jayshree Mahendra Thakkar
Abstract Background COVID-19 patients with respiratory failure may need intensive care unit (ICU) admission. Prone positioning in mechanically ventilated patients improves oxygenation and reduces mortality in moderate to severe acute respiratory distress syndrome. For better oxygenation and outcomes, awake proning is being tried in non-intubated patients also. Our aim was to investigate advantage of awake self-prone positioning with oxygen therapy using non-rebreathing mask (NRBM) in COVID-19 ICU patients. Results This prospective observational study was conducted in ICU from 18th November 2020 to 28th February 2021. Sixty COVID-19 cooperative patients with hypoxemia on arrival with hemodynamic stability were included. Patients on NRBM were advised to turn prone for 12–14 h per day. Oxygen saturation (SpO 2 ) was recorded in supine position and 30 min after initiation of prone positioning. Ratio of arterial partial pressure of oxygen and fractional concentration of inspired oxygen (P/F) was recorded in supine and 24 h after initiation of prone position. Primary outcome was improvement in SpO 2 > 94%. Secondary outcome was incidence of intubation. Sixty patients were received in ICU with supplemental oxygen, and median SpO 2 was 80% ( IQR 70–88%). Patients were put on NRBM with median SpO 2 in supine position 86% ( IQR 76–90). Thirty minutes of proning increased SpO 2 to 94% ( IQR 89 to 97%). Wilcoxon rank-sum test was used ( P = 0.001). Forty-three patients did not require intubation, and seventeen patients needed intubation. Conclusions Awake self-proning in COVID-19 patients on NRBM improved oxygenation with reduced intubation rate.
背景COVID-19合并呼吸衰竭患者可能需要入住重症监护病房(ICU)。机械通气患者俯卧位可改善氧合,降低中重度急性呼吸窘迫综合征的死亡率。为了更好的氧合和结果,清醒俯卧也正在非插管患者中进行试验。我们的目的是探讨醒时自我俯卧位配合非再呼吸面罩(NRBM)吸氧治疗在COVID-19 ICU患者中的优势。该前瞻性观察性研究于2020年11月18日至2021年2月28日在ICU进行。纳入60例入院时低氧血症且血流动力学稳定的COVID-19合作患者。建议NRBM患者每天俯卧12-14小时。在仰卧位和俯卧位开始后30分钟记录血氧饱和度(SpO 2)。记录仰卧位和俯卧位24 h时动脉血氧分压与吸入氧分数浓度之比(P/F)。主要结局是spo2和gt的改善;94%。次要终点为插管发生率。60例患者在ICU接受补充氧治疗,中位spo2为80% (IQR 70 ~ 88%)。患者采用NRBM,中位spo2为仰卧位86% (IQR 76-90)。30分钟的锻炼使spo2增加到94% (IQR为89 - 97%)。采用Wilcoxon秩和检验(P = 0.001)。43例患者不需要插管,17例患者需要插管。结论新型冠状病毒肺炎患者经NRBM治疗后清醒自我调整可改善氧合,降低插管率。
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引用次数: 0
Dexmedetomidine or magnesium to control agitations in patients undergoing tonsillectomy: randomised controlled study 右美托咪定或镁控制扁桃体切除术患者的躁动:随机对照研究
Q4 ANESTHESIOLOGY Pub Date : 2023-11-03 DOI: 10.1186/s42077-023-00384-w
Beshoy Gamal Nazeem Saad, Basem Boles Gabriale Saad, Ashraf EL Said Abd EL Rahman EL Agamy, Mona Ahmed Abd Elmotalb Ammar, Khaled Moustafa Ali Khalaf
Abstract Background Preoperative time is a very stressful time for most patients undergoing surgery, particularly young patients. The primary goal of an anaesthesiologist is to reduce patients’ anxiety before surgery. To lessen this stress response, many anaesthetic pre-medications are used. Magnesium chloride and dexmedetomidine are two of these pre-medications that work well as sedatives. This study examined dexmedetomidine and magnesium sulphate as a pre-anaesthetic medication for kids. Dexmedetomidine and magnesium will be compared for their efficacy and safety in treating children who experience emerging anxiety after having their tonsils removed in this trial. Forty-five children between the ages of 4 and 12 years who were having elective adenotonsillectomy surgery in this comparative prospective, double-blind, randomised controlled clinical research. Children were split up into three groups: group A was given dexmedetomidine, group B was given magnesium infusion, and group C was given normal saline 0.9% infusion. Results Ramsay and Cravero scores revealed that children who got dexmedetomidine infusion were less agitated than those who received magnesium sulphate or normal saline infusion ( p value 0.01). Conclusions When comparing dexmedetomidine to magnesium sulphate, there are a few advantages to its use. It can be administered as an anaesthetic medication to minors undergoing adenotonsillectomy under general anaesthesia in order to lessen postoperative agitation.
背景对于大多数接受手术的患者,尤其是年轻患者来说,术前时间是一个非常紧张的时间。麻醉师的首要目标是减少病人在手术前的焦虑。为了减轻这种应激反应,使用了许多麻醉前药物。氯化镁和右美托咪定是其中两种作为镇静剂效果很好的前用药。本研究考察了右美托咪定和硫酸镁作为儿童麻醉前药物的作用。在这项试验中,右美托咪定和镁在治疗扁桃体切除后出现焦虑症状的儿童方面的疗效和安全性将进行比较。在这项比较前瞻性、双盲、随机对照的临床研究中,45名年龄在4至12岁之间接受选择性腺扁桃体切除术的儿童。将患儿分为3组:A组患儿给予右美托咪定,B组患儿给予镁注射液,C组患儿给予0.9%生理盐水注射液。结果Ramsay和Cravero评分显示右美托咪定组患儿的躁动程度低于硫酸镁组和生理盐水组(p值0.01)。结论右美托咪定与硫酸镁比较,其使用优势较少。它可以作为麻醉药物给未成年人在全麻下进行腺扁桃体切除术,以减少术后躁动。
{"title":"Dexmedetomidine or magnesium to control agitations in patients undergoing tonsillectomy: randomised controlled study","authors":"Beshoy Gamal Nazeem Saad, Basem Boles Gabriale Saad, Ashraf EL Said Abd EL Rahman EL Agamy, Mona Ahmed Abd Elmotalb Ammar, Khaled Moustafa Ali Khalaf","doi":"10.1186/s42077-023-00384-w","DOIUrl":"https://doi.org/10.1186/s42077-023-00384-w","url":null,"abstract":"Abstract Background Preoperative time is a very stressful time for most patients undergoing surgery, particularly young patients. The primary goal of an anaesthesiologist is to reduce patients’ anxiety before surgery. To lessen this stress response, many anaesthetic pre-medications are used. Magnesium chloride and dexmedetomidine are two of these pre-medications that work well as sedatives. This study examined dexmedetomidine and magnesium sulphate as a pre-anaesthetic medication for kids. Dexmedetomidine and magnesium will be compared for their efficacy and safety in treating children who experience emerging anxiety after having their tonsils removed in this trial. Forty-five children between the ages of 4 and 12 years who were having elective adenotonsillectomy surgery in this comparative prospective, double-blind, randomised controlled clinical research. Children were split up into three groups: group A was given dexmedetomidine, group B was given magnesium infusion, and group C was given normal saline 0.9% infusion. Results Ramsay and Cravero scores revealed that children who got dexmedetomidine infusion were less agitated than those who received magnesium sulphate or normal saline infusion ( p value 0.01). Conclusions When comparing dexmedetomidine to magnesium sulphate, there are a few advantages to its use. It can be administered as an anaesthetic medication to minors undergoing adenotonsillectomy under general anaesthesia in order to lessen postoperative agitation.","PeriodicalId":7686,"journal":{"name":"Ain-Shams Journal of Anesthesiology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135868260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidural catheter migration: is aspiration enough? A case report 硬膜外导管移位:吸入足够吗?病例报告
Q4 ANESTHESIOLOGY Pub Date : 2023-11-03 DOI: 10.1186/s42077-023-00385-9
Ravi Murmu, A. Aditya, P. K. Tiwary, Ladhu Lakra, Tushar Kumar
Abstract Background Local anesthetic agents are widely used drugs across the globe. Within their dosage range and appropriate location of administration, they are quite safe and effective. Rarely when given via intravascular route, local anesthetics can lead to life-threatening consequences. Case presentation Here, we present a case of a young male with an epidural catheter for femur surgery. The catheter was functioning quite well initially but later migrated in the intravascular route. When top-up was given with local anesthetics, the patient developed seizures which were managed promptly. Conclusions Inadvertent migration of catheter may occur during patient positioning or unwanted movements during surgery, but careful aspiration before every top-up and aspiration during every aliquot of top-up must be practiced.
摘要背景局麻药是全球范围内广泛使用的药物。在其剂量范围和适当的给药位置,它们是相当安全有效的。当通过血管内途径给予局部麻醉剂时,很少会导致危及生命的后果。病例报告在此,我们报告一例年轻男性在股骨手术中使用硬膜外导管。导管最初功能良好,但后来在血管内转移。当给予局部麻醉剂补充时,患者出现癫痫发作,并得到及时处理。结论在患者体位过程中可能会出现导管的不小心移动或手术过程中不希望发生的移动,但在每次补位前和每次补位过程中都必须仔细抽吸。
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引用次数: 0
Perioperative management of a morbidly obese patient with multiple myeloma for spine surgery—when the problem doubles up! 一例患有多发性骨髓瘤的病态肥胖脊柱手术患者的围手术期处理——当问题加倍时!
Q4 ANESTHESIOLOGY Pub Date : 2023-10-26 DOI: 10.1186/s42077-023-00375-x
Shankey Garg, Shalvi Mahajan, Ankit Kansal, Swati Taneja
Abstract Background Multiple myeloma (MM) patients are prone to pathological fractures due to osteolytic bone lesions. With improved perioperative care, outcome of patients with vertebral compression fractures presenting for surgical interventions has become better. However, perioperative care of such patients is challenging for the anesthesiologist. Case presentation Herein, we report the successful perioperative management of a 55-year-old multiple myeloma patient with the compression fracture of lumbar vertebrae 2nd to 5th, for which balloon kyphoplasty was planned in prone position. Conclusions Multiple myeloma patients are at high risk of developing postoperative complications like acute kidney injury (AKI), pneumonia, and infections. In the present case report, we discuss and provide recommendations for better perioperative care to prevent perioperative complications.
背景多发性骨髓瘤(Multiple myeloma, MM)患者易因骨溶解性病变而发生病理性骨折。随着围手术期护理的改善,椎体压缩性骨折患者接受手术治疗的结果变得更好。然而,这类患者的围手术期护理对麻醉师来说是一个挑战。在此,我们报告一例55岁多发性骨髓瘤患者伴第2至第5腰椎压缩性骨折的围手术期成功处理,该患者计划采用俯卧位球囊后凸成形术。结论多发性骨髓瘤患者术后发生急性肾损伤(AKI)、肺炎、感染等并发症的风险较高。在本病例报告中,我们讨论并提供更好的围手术期护理建议,以防止围手术期并发症。
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引用次数: 0
Comparative study on regression time of block and adverse effects of nalbuphine and fentanyl as an adjuvant to intrathecal bupivacaine: a prospective randomized double-blind study 纳布啡与芬太尼鞘内辅助布比卡因阻滞消退时间及不良反应的比较研究:前瞻性随机双盲研究
Q4 ANESTHESIOLOGY Pub Date : 2023-10-26 DOI: 10.1186/s42077-023-00382-y
Kamal Chandra Deori, Mrinal Kanti Taye, Babita Lahkar
Abstract Background The study was done to observe the effectiveness of nalbuphine as an adjuvant to intrathecal bupivacaine heavy, and hence, it was compared in terms of regression time of sensory and motor block and adverse effects with that of fentanyl as an adjuvant. The study design was a prospective randomized double-blind study. Total number of patients were 100. They were randomly allocated into two groups. Group N ( n = 50) received 3.2 ml of 0.5% heavy bupivacaine and 0.5 ml (0.8 mg) of nalbuphine, a total of 3.7 ml. Group F ( n = 50) received 3.2 ml of 0.5% heavy bupivacaine and 0.5 ml (25 µg) of fentanyl, a total of 3.7 ml. Assessment of sensory and motor blockade and analgesia was done by visual analogue scale and modified Bromage scale. Results On comparing the spinal block characteristics among two groups to reach, Bromage-3 motor block was found to be significantly shorter in group F ( p = 0.03777). The regression time of both sensory and motor block was significantly prolonged in group N ( P < 0.0001). No patients required additional analgesic intraoperatively, and intraoperative VAS scores and adverse effects were comparable in the two groups. Conclusions On comparing nalbuphine 0.8 mg and fentanyl 25 µg as an adjuvant to intrathecal bupivacaine, it has been observed that nalbuphine significantly prolongs regression time of sensory and motor block indicating the effectiveness of nalbuphine as an alternative to fentanyl and for prolong surgeries. The incidence of adverse effects was similar in both groups.
摘要背景本研究旨在观察纳布啡辅助治疗鞘内布比卡因的有效性,并与芬太尼辅助治疗在感觉和运动阻滞的消退时间及不良反应方面进行比较。研究设计为前瞻性随机双盲研究。患者总数100例。他们被随机分为两组。N组(N = 50)给予0.5%重布比卡因3.2 ml和纳布啡0.5 ml (0.8 mg),共3.7 ml; F组(N = 50)给予0.5%重布比卡因3.2 ml和芬太尼0.5 ml(25µg),共3.7 ml。采用视觉模拟量表和改良Bromage量表评估感觉和运动阻断及镇痛效果。结果比较两组脊髓阻滞特征,F组Bromage-3运动阻滞明显短于F组(p = 0.03777)。N组感觉阻滞和运动阻滞的消退时间均显著延长(P <0.0001)。术中无患者需要额外镇痛,两组术中VAS评分和不良反应具有可比性。结论对比纳布啡0.8 mg和芬太尼25µg作为鞘内布比卡因的辅助剂,发现纳布啡显著延长了感觉和运动阻滞的消退时间,提示纳布啡可替代芬太尼,延长手术时间。两组不良反应发生率相似。
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引用次数: 0
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Ain-Shams Journal of Anesthesiology
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