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Synthesis and Characterization of Fatty Acid Furfuryl Ester Mixtures: Biodiesel from Furfuryl Alcohol 脂肪酸-糠醇酯混合物的合成与表征:糠醇生物柴油
Amanda L. Raley, Jenny P. Beldin, Russell J. Franks
The synthesis of biodiesel fuels from triacylglycerols and common alcohols such as methanol and ethanol has been reported using a variety of methods and catalysts. As part of an effort to explore the properties of biodiesel fuels made from novel feedstocks, furfuryl alcohol is used as the alcohol component in biodiesel synthesis. Commercially-available cooking oils were transesterified using furfuryl alcohol and K2CO3 in the presence of a room-temperature ionic liquid catalyst. The resulting product is a fatty acid furfuryl ester (FAFurE) mixture. After purification, the FAFurE product mixtures were analyzed using 1H-NMR spectroscopy. Percentage conversion values were calculated using integration data from the NMR spectra. Percent conversion values ranged from 19 to 75%. The wide range in percent conversion has been attributed to steric interactions between the bulky nucleophile and polyunsaturated fatty acid chains in the oils used. This work represents a proof-of-concept that furfuryl alcohol can serve as an alternative alcohol source for biodiesel fuels or biodiesel additives.
从甘油三酯和常见醇如甲醇和乙醇合成生物柴油燃料已经有了使用多种方法和催化剂的报道。作为探索新型原料制备生物柴油性能的一部分,糠醇被用作合成生物柴油的醇组分。在室温离子液体催化剂的存在下,用糠醇和K2CO3对市售食用油进行酯交换反应。所得产物是脂肪酸糠酰酯(future)混合物。纯化后,使用1H-NMR对fuure产品混合物进行分析。利用核磁共振光谱的积分数据计算百分比转换值。百分比转换值从19%到75%不等。转化率的广泛范围归因于所使用的油中大块亲核试剂和多不饱和脂肪酸链之间的空间相互作用。这项工作代表了糠醇可以作为生物柴油燃料或生物柴油添加剂的替代酒精来源的概念证明。
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引用次数: 3
nvironmental Monitoring of NOX, Total Oxidants and the Implications for Photochemistry of Air Pollution over Ilorin Shed, Nigeria 尼日利亚Ilorin Shed地区氮氧化物、总氧化剂的环境监测及其对空气污染光化学的影响
A. Raheem, A. Adekola, Obioh Obioh
The assessment of oxides of nitrogen (NO X ) and total oxidants as ozone (O 3 ) over the air shed of a typical average tropical equatorial city monitored with the aid of high volume sampler for three years is presented using three urban site classes and a control. The mean concentrations for all sites during wet season (May October) were 3.31 ± 0.40 ppb for NO X , 21.86 ± 2.47 for O 3 while the dry season (November - April) mean concentration values were 2.03 ± 0.23 ppb for NO x and 32.44 ± 5.13 for O 3 . Mean value at the control site was an order of magnitude lower than the urban sites during the two seasons except concentration of O 3 higher during the dry season. Traffic density and trace gas concentrations showed good correlation of 0.98 (P<0.05). NO x was confirmed to be a strong precursor for O 3 formation. The influence of Harmattan dust in impeding the photochemistry of O 3 formation from November to January (NDJ) months was observed. The overall concentration levels of NOx and O 3 for the air shed are 2.67 ± 0.32 and 27.15 ± 3.8 respectively, within the limit of United States Environmental Protection Agency (USEPA) guidelines for air quality standards.
利用高容量采样器对一个典型的热带赤道城市空气棚内的氮氧化物(NO X)和总氧化剂臭氧(O 3)进行了3年的监测,采用3个城市站点类别和一个对照。丰水期(5 ~ 10月)各站点NO X和o3的平均浓度分别为3.31±0.40 ppb和21.86±2.47 ppb,枯水期(11 ~ 4月)NO X和o3的平均浓度分别为2.03±0.23 ppb和32.44±5.13 ppb。除o3浓度在旱季较高外,对照区2个季节的平均值均低于市区1个数量级。交通密度与微量气体浓度呈良好的相关关系(0.98)(P<0.05)。NO x被证实是O 3形成的强前体。观察了11月~ 1月(NDJ月)沙尘对o3光化学形成的影响。空气棚内NOx和o3的总浓度分别为2.67±0.32和27.15±3.8,在美国环境保护署(USEPA)空气质量标准指导方针的限制范围内。
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引用次数: 1
Increased Oxidative/Nitrosative Stress in Common Metabolic Diseases in Gaziantep Region 加济安泰普地区常见代谢性疾病中氧化/亚硝化应激增加
M. Tarakçıoğlu, H. Ulusal, M. Keskin, Y. Tuncer, S. Taysı
The balance between oxidative/nitrosative stress and antioxidant activity has an important role in oxidative stress associated diseases such as phenylketonuria (PKU) and maple syrup urine disease (MSUD). We aimed in this study to evaluate the possible association between oxidative/nitrosative balance and clinical features of PKU and MSUD patients. The study included 22 controls, 40 PKU and 18 MSUP patients. Serum malondialdehyde (MDA), peroxynitrite (ONOO-), 8-OH deoxyguanosine (8-OHdG), oxidative DNA damage marker, levels and some amino acid in plasma of patients were measured. Serum MDA and ONOOlevels were significantly higher in PKU and MSUD patients compared to the control group. Plasma valine leucine, isoleucine and phenylalanine levels were significantly higher in MSUD patients than in the control and PKU groups. Similarly, plasma phenylalanine levels were significantly higher in PKU patients compared to control and MSUP group. There was no difference between 8-OHdG levels when all groups were compared. Consequently, the results of this study clearly show that oxidative / nitrosative stress increases in patients with PKU and MSUD. Antioxidant supplementation may be beneficial in the treatment of these patients.
氧化/亚硝化应激和抗氧化活性之间的平衡在氧化应激相关疾病如苯丙酮尿症(PKU)和枫糖尿病(MSUD)中起重要作用。我们在这项研究中旨在评估PKU和MSUD患者的氧化/亚硝化平衡与临床特征之间可能的关联。该研究包括22例对照组、40例PKU和18例MSUP患者。测定患者血清丙二醛(MDA)、过氧亚硝酸盐(ONOO-)、8-OH脱氧鸟苷(8-OHdG)、氧化DNA损伤标志物及血浆部分氨基酸水平。与对照组相比,PKU和MSUD患者血清MDA和onoolol水平显著升高。MSUD患者血浆缬氨酸、亮氨酸、异亮氨酸和苯丙氨酸水平明显高于对照组和PKU组。同样,PKU患者血浆苯丙氨酸水平明显高于对照组和MSUP组。当所有组进行比较时,8-OHdG水平没有差异。因此,本研究的结果清楚地表明,PKU和MSUD患者的氧化/亚硝化应激增加。抗氧化剂的补充可能对这些患者的治疗有益。
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引用次数: 0
Determination of Agmatine Rate by Spectrofluorimetric Method in Alkaline Medium: Optimization and Application on Shrimp. 荧光光谱法测定碱性培养基中Agmatine的含量:优化及在对虾上的应用。
Khémesse Kital, M. Traoré, Diégane Sarr, M. Mbaye, O. Mbaye, L. Cissé, M. D. G. Seye, A. Coly, F. Delattre, A. Tine
In this work, a spectrofluorimetric method was developed to determine the rate of agmatine (AGM) in shrimp using orthophthalaldehyde (OPA) as derivatization agent. To optimize analytical results, the stoichiometry of the orthophthalaldehyde-agmatine complex (OPA-AGM) was determined. The effects of agitation and temperature on the fluorescence spectra of the complex in alkaline medium (pH 13) were then studied. We obtained in all media satisfactory analytical performances with very low detection limits (DL) ranging from 0.36 to 2.52 ng/mL and a quantification limit (QL) oF 1.62 to 8.40 ng/mL The relative standard deviations (RSD) obtained ranged from 0.08 to 1.5%, which shows the excellent replicability of measurements. In addition, recovery rates found in shrimp extract, between 96.3% and 103.4%, show the accuracy of measurements. Lastly, the interference effects on the determination of agmatine rate with biogenic amines and some metal ions likely to be present in shrimp were studied.
本文以邻苯二醛(OPA)为衍生剂,建立了测定虾中胍丁氨酸(AGM)含量的荧光光谱法。为了优化分析结果,对邻苯二甲酸乙酯配合物(OPA-AGM)进行了化学计量学测定。然后研究了搅拌和温度对配合物在碱性介质(pH 13)中荧光光谱的影响。检测限(DL)为0.36 ~ 2.52 ng/mL,定量限(QL)为1.62 ~ 8.40 ng/mL,相对标准偏差(RSD)为0.08 ~ 1.5%,具有良好的重复性。此外,在虾提取物中发现的回收率在96.3%至103.4%之间,表明了测量的准确性。最后,研究了虾体内可能存在的生物胺和一些金属离子对测定胍丁氨酸率的干扰作用。
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引用次数: 3
Short Communication 简短的沟通
Mayank Jain
Aim of the studyTo analyze the referral pattern, indications and results of esophageal manometry in our setting. MethodsIn this retrospective study, manometry records of all consecutive patients who underwent esophageal manometry from January 2013 to June 2015 were analyzed. The results were interpreted as per Chicago classification v.3.0. The data was entered in Microsoft excel sheet and analyzed using necessary tests. Results-A total of 220 patients with a mean age of 45 years and male to female ratio of 7:4 formed the study group. The indications for manometric evaluation includeddysphagia (87,39.54%), gastroesophageal reflux(76,34.54%) , non-cardiac chest pain(25,11.36%), dyspepsia(20,9.09%) and prior to fundoplication surgery(12,5.45%). , 39.1% patients could be diagnosed with a definitive motility disorder while 29% had ineffective motility or frequently failed peristalsis. 36% patients had a normal study. ConclusionsEsophageal manometry in our setting is done mainly for dysphagia and reflux symptoms. The main referrals are from fellow gastroenterologists and surgeons. In 39% of cases, a definite diagnosis is possible. Achalsiacardia is the most common cause of motor dysphagia.
目的分析食道测压的转诊方式、适应证及结果。方法回顾性分析2013年1月至2015年6月连续行食管测压术患者的测压记录。结果按照芝加哥分类v.3.0进行解释。将数据输入到Microsoft excel表格中,并使用必要的测试进行分析。结果:研究组共220例患者,平均年龄45岁,男女比例7:4。压力计评估指征包括吞咽困难(87例,39.54%)、胃食管反流(76例,34.54%)、非心源性胸痛(25例,11.36%)、消化不良(20例,9.09%)和手术前(12例,5.45%)。39.1%的患者可诊断为明确的运动障碍,29%的患者运动功能低下或经常蠕动失败。36%的患者研究正常。结论食道压力测量主要用于吞咽困难和反流症状。主要的转诊是来自同事胃肠病学家和外科医生。39%的病例可以得到明确的诊断。贲门失弛缓是运动性吞咽困难的最常见原因。
{"title":"Short Communication","authors":"Mayank Jain","doi":"10.1515/cclm.1995.33.7.441","DOIUrl":"https://doi.org/10.1515/cclm.1995.33.7.441","url":null,"abstract":"Aim of the studyTo analyze the referral pattern, indications and results of esophageal manometry in our setting. MethodsIn this retrospective study, manometry records of all consecutive patients who underwent esophageal manometry from January 2013 to June 2015 were analyzed. The results were interpreted as per Chicago classification v.3.0. The data was entered in Microsoft excel sheet and analyzed using necessary tests. Results-A total of 220 patients with a mean age of 45 years and male to female ratio of 7:4 formed the study group. The indications for manometric evaluation includeddysphagia (87,39.54%), gastroesophageal reflux(76,34.54%) , non-cardiac chest pain(25,11.36%), dyspepsia(20,9.09%) and prior to fundoplication surgery(12,5.45%). , 39.1% patients could be diagnosed with a definitive motility disorder while 29% had ineffective motility or frequently failed peristalsis. 36% patients had a normal study. ConclusionsEsophageal manometry in our setting is done mainly for dysphagia and reflux symptoms. The main referrals are from fellow gastroenterologists and surgeons. In 39% of cases, a definite diagnosis is possible. Achalsiacardia is the most common cause of motor dysphagia.","PeriodicalId":77119,"journal":{"name":"European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/cclm.1995.33.7.441","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67394019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short Communication 简短的沟通
S. Yazdani, M. Sharbatdaran, M. Samakoosh, Z. Bouzari, Z. Masoudi
Background: Bilateral salpingo-oophorectomy in women may lead to metabolic consequences in patients. This study was performed to determine the glucose tolerance and lipid profile after menopause resulting from bilateral salpingo-oophorectomy. Methods: From September 2011 to March 2013, 31 women participants aged 46-52 years who underwent hysterectomy and bilateral salpingo-oophorectomy for benign reasons were recruited. An oral glucose tolerance test (OGTT), triglyceride (TG), total cholesterol, low density lipoproteis (LDL), high density lipoprotein (HDL) was performed before and 6 months after surgery. Fasting insulin and 2-hour insulin levels, fasting insulin / glucose indexes and homeostasis model assessment HOMA indexes were also measured. Results: The mean age of the patients was 48.6±2.9 years. The mean 2-h glucose level in OGTT changed from 26.7 before surgery to 111.1 μUnit/ml (P=0.030). The mean level of lipid profile before and after surgery for TG was 132.3 versus 181.2 mg/dl (P=0.005), total cholesterol 177.4 versus 206.7 mg/dl (P=0.0001) and LDL 98.4 versus 115.3 mg/dl (P=0.003). The other variables showed no significant difference. Conclusion: The results indicate that lipid profile changes like increase of TG, total cholesterol and LDL should be considered before removing the ovary during hysterectomy in premenopausal women.
背景:女性双侧输卵管卵巢切除术可能导致患者的代谢后果。本研究旨在确定双侧输卵管-卵巢切除术后绝经后的糖耐量和脂质谱。方法:选取2011年9月至2013年3月因良性原因行子宫切除术和双侧输卵管卵巢切除术的女性31例,年龄46 ~ 52岁。术前、术后6个月分别进行口服葡萄糖耐量试验(OGTT)、甘油三酯(TG)、总胆固醇、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)检测。同时测量空腹胰岛素和2小时胰岛素水平、空腹胰岛素/血糖指数和稳态模型评估HOMA指数。结果:患者平均年龄48.6±2.9岁。OGTT平均2 h葡萄糖水平由术前的26.7 μUnit/ml降至111.1 μUnit/ml (P=0.030)。手术前后的平均血脂水平TG为132.3 vs 181.2 mg/dl (P=0.005),总胆固醇为177.4 vs 206.7 mg/dl (P=0.0001), LDL为98.4 vs 115.3 mg/dl (P=0.003)。其他变量无显著性差异。结论:绝经前妇女子宫切除术前应考虑TG、总胆固醇、LDL升高等血脂变化。
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引用次数: 0
TECHNICAL NOTE 技术报告
E. F. V. D. Hil, K. Beekmann, J. Keijer, P. Hollman, I. Rietjens, E. M. Schothorst
Flavonoids are bioactive food compounds with potential lipid-lowering effects. Commercially available enzymatic assays are widely used to determine free fatty acid (FFA) and triglyceride (TG) levels both in vivo in plasma or serum and in vitro in cell culture medium or cell lysate. However, we have observed that various flavonoids interfere with peroxidases used in these enzymatic assays, resulting in incorrect lower FFA and TG levels than actually present. Furthermore, addition of isorhamnetin or the major metabolite of the flavonoid quercetin in human and rat plasma, quercetin-3-Oglucuronide, to murine serum also resulted in a significant reduction of the detected TG levels, while a trend was seen for FFA levels. It is concluded that when applying these assays, vigilance is needed and alternative analytical methods, directly assessing FFA or TG levels, should be used for studying the biological effects of flavonoids on FFA and TG levels.
类黄酮是具有潜在降脂作用的生物活性食品化合物。市售酶法被广泛用于测定体内血浆或血清中的游离脂肪酸(FFA)和甘油三酯(TG)水平,以及体外细胞培养基或细胞裂解液中的游离脂肪酸(FFA)和甘油三酯(TG)水平。然而,我们观察到,在这些酶分析中,各种类黄酮干扰过氧化物酶,导致不正确的FFA和TG水平低于实际存在。此外,在小鼠血清中添加异鼠李素或人和大鼠血浆中类黄酮槲皮素的主要代谢物槲皮素-3-葡萄糖醛酸也能显著降低检测到的TG水平,而FFA水平也有下降的趋势。综上所述,黄酮类化合物对游离脂肪酸和甘油三酯的生物学效应研究应采用直接测定游离脂肪酸或甘油三酯水平的替代分析方法。
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引用次数: 1
More on inter-method variability of sodium and potassium measurements in patients sera and control materials. 更多关于患者血清和对照材料中钠和钾测量的方法间差异。
F Zoppi, E Guagnellini, A Manzoni
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引用次数: 0
It is rational to measure serum lactate dehydrogenase isoenzyme-1 activity in patients with testicular germ cell tumours. 检测睾丸生殖细胞肿瘤患者血清乳酸脱氢酶同工酶-1活性是合理的。
F E von Eyben, P Hyltoft Petersen, O Blaabjerg, E Lindegaard Madsen
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引用次数: 0
The origins of the European Confederation of Laboratory Medicine (ECLM) 欧洲检验医学联合会(ECLM)的起源
R Dybkaer
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引用次数: 0
期刊
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies
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