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Trends in the incidence of cutaneous malignant melanomas in the south east of England, 1960-1998. 英格兰东南部皮肤恶性黑色素瘤的发病率趋势,1960-1998。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.268
A Newnham, H Møller

Background: Our aim was to describe the epidemiology of cutaneous malignant melanomas (CMMs) in males and females in the south east of England from 1960 to 1998. Birth cohort effects are important when describing the incidence of CMMs because fashions of dress affect whether different body sites are exposed to sunlight.

Methods: We calculated the age-standardized incidence of all CMMs for 5 year periods from 1960 to 1998 and the age-specific and age-standardized incidence of CMMs at different sites for 5 year periods from 1980 to 1998. We plotted age-specific incidence rates against period of diagnosis and birth cohort.

Results: The age-standardized incidence of CMMs increased from 1.3 to 7.1 per 100,000 person-years in males. Incidence increased from 2.4 to 7.8 per 100,000 person-years overall in females but levelled in the 1990s. Trunk CMMs had the highest incidence in males and the greatest increase in incidence. Lower limb CMMs had the highest incidence in females but their incidence decreased. The rate of increase of the age-specific incidence of trunk CMMs was greater for male birth cohorts before about 1945. The rate of increase of the incidence of lower limb CMMs was greater for female birth cohorts before about 1920.

Conclusions: If current trends continue, the age-standardized incidence of CMMs in females will remain stable. The increase in the age-standardized incidence of CMMs in males was driven by increases in the age-specific incidence of trunk CMMs in men who were born before about 1949. As they age, age-standardized incidence should level.

背景:我们的目的是描述1960年至1998年英格兰东南部男性和女性皮肤恶性黑色素瘤(CMMs)的流行病学。出生队列效应在描述CMMs发病率时很重要,因为服装的时尚会影响不同的身体部位是否暴露在阳光下。方法:我们计算了1960 - 1998年5年间所有CMMs的年龄标准化发病率,以及1980 - 1998年5年间不同地点CMMs的年龄特异性发病率和年龄标准化发病率。我们根据诊断期和出生队列绘制了年龄特异性发病率。结果:男性CMMs的年龄标准化发病率从1.3 / 100000人年增加到7.1 / 100000人年。女性的发病率从每10万人年2.4人增加到7.8人,但在20世纪90年代保持不变。主干CMMs男性发病率最高,发病率增幅最大。下肢CMMs在女性中发病率最高,但发病率有所下降。在1945年以前出生的男性群体中,躯干CMMs的年龄特异性发病率的增长率更大。大约在1920年以前出生的女性中,下肢CMMs发病率的增长率更大。结论:如果目前的趋势继续下去,女性CMMs的年龄标准化发病率将保持稳定。男性cmmm年龄标准化发病率的增加是由1949年以前出生的男性中干cmmm年龄特异性发病率的增加所驱动的。随着年龄的增长,年龄标准化的发病率应该持平。
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引用次数: 32
Social and demographic predictors of parental consultation for child psychological difficulties. 儿童心理困难家长咨询的社会和人口预测因素。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.276
Mary M Haines, Anne McMunn, James Y Nazroo, Yvonne J Kelly

Background: Results from previous studies examining determinants of parental consultation for child mental health provide inconsistent evidence concerning socio-demographic predictors. The aim of this study is to identify the sociodemographic predictors of parental consultation for child psychological difficulties.

Method: An epidemiological cross-sectional analysis was carried out using a sample of 5,913 children aged between 4 and 15 years from the Health Survey for England. The Strengths and Difficulties Questionnaire (SDQ) was the measure of child psychological morbidity.

Results: Parents of children with psychological difficulties were less likely to seek a consultation if their child was a girl, as household income decreased or if the head of household came from manual social class. In contrast, parents were more likely to seek a consultation if they were in receipt of a benefit than if they were not in receipt of a benefit. Age of child and family type did not predict parental consultation.

Conclusions: The results of this analysis confirm that a substantial proportion of children with mental health difficulties in the general population (42 per cent) have not been seen by a professional, and these are likely to be girls and children in low-income families, indicating a significant unmet need for services across the nation. These results suggest that parents and health professionals should be made more aware of the symptoms of psychological problems in girls and that services need to be planned in a way that improves uptake by low-income parents.

背景:以前的研究结果检查了父母咨询儿童心理健康的决定因素,提供了关于社会人口预测因素的不一致的证据。本研究的目的是确定父母咨询儿童心理困难的社会人口学预测因素。方法:对来自英格兰健康调查的5,913名年龄在4至15岁之间的儿童进行流行病学横断面分析。优势与困难问卷(SDQ)是衡量儿童心理发病率的量表。结果:有心理障碍儿童的父母,如果孩子是女孩,家庭收入减少或户主来自手工社会阶层,则不太可能寻求咨询。相比之下,如果父母得到了福利,他们会比没有得到福利的父母更有可能寻求咨询。儿童年龄和家庭类型不能预测家长咨询。结论:这一分析的结果证实,在一般人口中,有相当大比例的有精神健康问题的儿童(42%)没有得到专业人员的治疗,这些儿童很可能是低收入家庭的女孩和儿童,这表明全国各地的服务需求严重未得到满足。这些结果表明,应使父母和保健专业人员更加了解女孩心理问题的症状,需要以提高低收入父母接受服务的方式来规划服务。
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引用次数: 41
Non-attendance at re-examination 20 years after screening in the British Regional Heart Study. 在英国区域心脏研究中,筛查20年后未参加复查。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.285
M C Thomas, M Walker, L T Lennon, A G Thomson, F C Lampe, A G Shaper, P H Whincup

Background: Maintenance of high participation rates in longitudinal studies is critical to their validity because of the possibility of bias associated with non-participation, which may differ between studies. This paper examines factors associated with participation status over time, by comparing the characteristics of non-attenders and attenders at a 20 year follow-up examination in a cardiovascular cohort study with an initial participation rate of 78 percent.

Methods: A baseline examination was carried out between 1978 and 1980 and subjects have been followed up through regular reviews of general practice records, postal questionnaires, and a clinical re-examination of survivors in 1998-2000. Data obtained by questionnaire in 1996 (Q96) and at baseline examination have been used to compare the characteristics of these recent non-attenders and attenders who remain in the cohort for further follow-up.

Results: The non-attendance rate of available survivors at re-examination was 23 per cent (n = 1313). Rates of non-attendance were highest in Scotland and lowest in Southern England. Non-attenders were older than attenders, more likely to smoke, and reported more disabling conditions and greater use of multiple medications at Q96, but recalled similar rates of diagnosed coronary heart disease. Marked differences in social factors were identified. Total mortality rates within 1 year of re-examination were over three times higher amongst non-attenders than attenders.

Conclusions: Non-attendance is related to health status, risk factor status and social circumstances and may affect some estimates of disease prevalence, but does not appearto have a major impact on the estimated prevalence of coronary heart disease. Information collected on non-attenders in longitudinal studies helps to estimate, adjust and minimize these effects.

背景:在纵向研究中保持高参与率对其有效性至关重要,因为不参与可能存在偏倚,这在不同的研究中可能有所不同。在一项初始参与率为78%的心血管队列研究中,通过比较20年随访检查中非参与者和参与者的特征,本文研究了随时间推移与参与状态相关的因素。方法:在1978年至1980年间进行了基线检查,并通过常规检查全科医生记录、邮寄问卷和1998年至2000年幸存者的临床复查对受试者进行了随访。通过1996年问卷调查(Q96)和基线检查获得的数据被用于比较这些最近未参加的参与者和留在队列中进行进一步随访的参与者的特征。结果:幸存者复查时未出勤率为23% (n = 1313)。不出勤率在苏格兰最高,在英格兰南部最低。非参与者年龄大于参与者,吸烟的可能性更大,在Q96中报告了更多的致残状况和更多的多种药物使用,但回忆起诊断为冠心病的比例相似。社会因素有显著差异。复查一年内的总死亡率,非参加者比参加者高出三倍以上。结论:不出勤与健康状况、危险因素状况和社会环境有关,并可能影响一些疾病患病率的估计,但似乎对冠心病患病率的估计没有主要影响。在纵向研究中收集的关于非参与者的信息有助于估计、调整和最小化这些影响。
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引用次数: 53
The impact of a television soap opera on the NHS Cervical Screening Programme in the North West of England. 一部电视肥皂剧对英格兰西北部NHS子宫颈筛查计划的影响。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.299
Andy Howe, Vicci Owen-Smith, Judith Richardson

Background: Mass media interventions can influence health care utilization but the effect of televised fictional accounts of illness upon national screening programmes is unknown. Our aim was to evaluate the impact of a Coronation Street story line, in which one of the characters died from cervical cancer, on the National Health Service (NHS) Cervical Screening Programme.

Methods: The study involved a retrospective analysis of information held on cervical screening databases ('Exeter' computer systems) of the nine Health Authorities constituting the Lancashire and Greater Manchester zones of the North West Region of the NHS. The number of cervical smears performed in the community, in women over 25 years of age, whose previous smear was normal and who were on routine recall, during a 6 month period that included the story line, was compared with those taken over the same period in the previous year. The proportions of smears classified by a screening interval of 'unscheduled', 'on time', 'overdue' or 'no previous smear' were compared.

Results: The number of smears performed increased from 65,714 in 2000 to 79,712 in 2001, an increase of 13,998 (21.3 percent; 95 per cent confidence interval (CI) 21.0-21.6 per cent) in the 19 weeks after the story line. The increase in the number of smears occurred in all categories of screening interval, with the largest increase seen in those attending 'on-time' (26 per cent).

Conclusions: We have demonstrated a large impact of a soap opera story line on the cervical screening programme although the benefit to health is not clear. Further research will determine the long-term effect of the story.

背景:大众媒体干预可以影响医疗保健的利用,但电视虚构的疾病描述对国家筛查计划的影响尚不清楚。我们的目的是评估《加冕街》故事线(其中一个角色死于子宫颈癌)对国民健康服务(NHS)子宫颈筛查计划的影响。方法:该研究涉及对构成NHS西北地区兰开夏郡和大曼彻斯特地区的九个卫生当局的子宫颈筛查数据库(“埃克塞特”计算机系统)中的信息进行回顾性分析。在包括故事情节在内的6个月期间,对社区中25岁以上妇女进行的子宫颈涂片检查的次数进行了比较,这些妇女以前的涂片检查是正常的,并进行了常规回忆。比较按筛查间隔划分为“未安排”、“准时”、“逾期”或“以前没有涂片”的涂片比例。结果:涂片检查次数从2000年的65,714次增加到2001年的79,712次,增加了13,998次(21.3%;95%置信区间(CI) 21.0- 21.6%)。涂片数量的增加发生在所有类别的筛查间隔中,其中“准时”参加的人数增幅最大(26%)。结论:我们已经证明了肥皂剧故事情节对子宫颈筛查计划的巨大影响,尽管对健康的益处尚不清楚。进一步的研究将确定这个故事的长期影响。
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引用次数: 62
Quarterly Communicable Disease Review April to June 2002. PHLS Communicable Disease Surveillance Centre. 传染病季刊2002年4月至6月。传染病监测中心。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.334
Jeremy Hawker
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引用次数: 0
A CLAS act? Community-based organizations, health service decentralization and primary care development in Peru. Local Committees for Health Administration. 集体行为?秘鲁的社区组织、保健服务权力下放和初级保健发展。地方卫生管理委员会。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.246
Michiyo Iwami, Roland Petchey

In 1994 Peru embarked on a programme of health service reform, which combined primary care development and community participation through Local Committees for Health Administration (CLAS). They are responsible for carrying out local health needs assessments and identifying unmet health needs through regular household surveys. These enable them to determine local health provision and tailor services to local requirements. CLAS build on grassroots self-help circles that developed during the economic and political crises of the 1980s, and in which women have been prominent. However, they function under a 3 year contract with the Ministry of Health and within a framework of centrally determined guidelines and regulations. These reforms were implemented in the context of neo-liberal economic policies, which stressed financial deregulation and fiscal and monetary restraint, and were aimed at reducing foreign indebtedness and inflation. We evaluate the achievements of the CLAS and analyse the relationship between health and economic policy in Peru, with the aid of two contrasting models of the role of the state - 'agency' and 'stewardship'. We argue that Peru's experience holds valuable lessons for other countries seeking to foster community involvement. These include the need for community capacity building and partnership between community organizations and state (and other civil) agencies.

1994年,秘鲁开始实施一项保健服务改革方案,通过地方卫生行政委员会将初级保健发展与社区参与结合起来。他们负责开展地方卫生需求评估,并通过定期家庭调查确定未得到满足的卫生需求。这使它们能够确定当地提供的保健服务,并根据当地需要定制服务。CLAS建立在20世纪80年代经济和政治危机期间发展起来的基层自助圈的基础上,其中妇女一直很突出。但是,它们根据与卫生部签订的为期三年的合同,在中央确定的指导方针和条例框架内运作。这些改革是在新自由主义经济政策的背景下实施的,这些政策强调放松金融管制和财政和货币限制,目的是减少外债和通货膨胀。我们评估了CLAS的成就,并借助国家作用的两种截然不同的模式——“机构”和“管理”——分析了秘鲁卫生与经济政策之间的关系。我们认为,秘鲁的经验为寻求促进社区参与的其他国家提供了宝贵的教训。其中包括社区能力建设的需要以及社区组织与国家(和其他民间)机构之间的伙伴关系。
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引用次数: 56
Evaluating the quality of internet-based information about alternative therapies: development of the BIOME guidelines. 评估基于互联网的替代疗法信息的质量:BIOME指南的制定。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.261
Alison Cooke, Lisa Gray

Background: The aim of the study was to develop guidelines for evaluating the quality of Internet-based information about alternative therapies.

Method: An expert committee drafted a set of guidelines for evaluating information relating to alternative therapies. The guidelines were subsequently refined by testing them using resources already included in the BIOME databases. The first 20 unique web sites about alternative therapies for cancer retrieved using a general search engine and a United Kingdom focused search engine were then evaluated using the refined guidelines. Those undertaking the evaluations also completed a questionnaire relating to the face and content validity of the guidelines. The participants in the implementation stage were six content providers. Content providers identify, evaluate and describe resources for inclusion in the BIOME databases.

Results: Only one web site out of 20 was selected by all six content providers for inclusion in the BIOME databases according to the alternative therapies guidelines. All content providers were in agreement regarding the exclusion of nine sites, but there were discrepancies regarding the remaining 10 resources. There was general agreement that the guidelines were easy to understand and that all points raised were necessary. However, there were differences of opinion regarding whether all issues were covered, whether the guidelines allowed the selection of only the highest quality resources, and whether the guidelines were applicable to a wide range of Internet-based resources about alternative therapies.

Conclusions: The levels of inconsistencies in the results indicate the need for the further development of the BIOME guidelines for selecting information about alternative therapies.

背景:本研究的目的是为评估基于互联网的替代疗法信息的质量制定指南。方法:一个专家委员会起草了一套评估替代疗法相关信息的指南。随后,通过使用生物组数据库中已经包含的资源进行测试,对准则进行了改进。使用通用搜索引擎和以英国为重点的搜索引擎检索到的前20个关于癌症替代疗法的独特网站,然后使用改进的指南进行评估。那些进行评价的人还填写了一份关于准则的表面和内容有效性的调查表。实施阶段的参与者是六个内容提供者。内容提供者识别、评估和描述要纳入BIOME数据库的资源。结果:根据替代疗法指南,所有六个内容提供商在20个网站中只有一个被选中纳入BIOME数据库。所有内容提供者都同意排除9个网站,但对其余10个资源存在差异。大家普遍同意,这些指导方针很容易理解,提出的所有要点都是必要的。然而,对于是否涵盖所有问题、指南是否只允许选择最高质量的资源,以及指南是否适用于广泛的基于互联网的替代疗法资源,意见存在分歧。结论:结果的不一致程度表明需要进一步制定BIOME指南,以选择有关替代疗法的信息。
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引用次数: 12
First, first among equals, or equals? Challenging the medical role in public health. 第一,平等的第一,还是平等的第一?挑战医疗在公共卫生中的作用。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.341-a
Frank Houghton
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引用次数: 1
Views of Directors of Public Health about NICE Appraisal Guidance: results of a postal survey. National Institute for Clinical Excellence. 公共卫生主管对NICE评估指南的看法:一项邮政调查的结果。国家临床卓越研究所。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.319
Elizabeth Davies, Peter Littlejohns

Background: We aimed to determine the views of Directors of Public Health about the Health Technology Appraisal Programme of the National Institute for Clinical Excellence (NICE) before the move to strategic health authorities and primary care trusts in April 2002.

Method: In December 2001 we sent a questionnaire asking about the work programme, products, decision-making, general approach, resource allocation and success of NICE to all Directors of Public Health in England and Wales. Ninety-two of 100 responded.

Results: Three-quarters or more agreed that NICE has covered a number of priority and controversial areas, produced good-quality health technology appraisals, well-presented reports and readable guidance in a consistent format, that it has raised the profile of clinical effectiveness, provided a focus for debate about health technology, and succeeded in making the National Health Service (NHS) set aside resources for approved technologies. A similar proportion, however, also agreed that guidance was not timely, did not address 'whole systems' and made some disappointing recommendations, and that decision-making was not influenced enough by the needs of the NHS. They considered that NICE did not address implementation, decide between competing technologies or help the service prioritization debate, and that guidance sent unrealistic signals about affordability to patients and politicians and caused difficulty for the implementation of other technologies locally.

Conclusions: A majority of Directors are positive about NICE's role of providing high-quality appraisal and central guidance but negative about its influence on local priority setting. Major concerns remain about the affordability of competing demands, whether this is NICE's responsibility or not.

背景:我们的目的是在2002年4月转移到战略卫生当局和初级保健信托基金之前,确定公共卫生主管对国家临床卓越研究所(NICE)卫生技术评估计划的看法。方法:2001年12月,我们向英格兰和威尔士的所有公共卫生主任发送了一份问卷,询问NICE的工作方案、产品、决策、一般方法、资源分配和成功情况。100人中有92人回应了。结果:四分之三或更多的人同意NICE涵盖了一些优先和有争议的领域,产生了高质量的卫生技术评估,以一致的格式提供了良好的报告和可读的指导,它提高了临床有效性的形象,为关于卫生技术的辩论提供了焦点,并成功地使国家卫生服务(NHS)为批准的技术预留了资源。然而,同样比例的人也同意,指导不及时,没有解决“整个系统”,并提出了一些令人失望的建议,决策没有受到NHS需求的足够影响。他们认为,NICE没有解决实施问题,在竞争技术之间做出决定,也没有帮助服务优先级的辩论,而且该指导向患者和政治家发出了关于负担能力的不切实际的信号,并给当地其他技术的实施带来了困难。结论:大多数董事对NICE提供高质量评估和集中指导的作用持肯定态度,但对其对地方优先事项设置的影响持否定态度。主要的担忧仍然是竞争需求的可承受性,不管这是不是NICE的责任。
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引用次数: 20
Future role of public health medicine. 公共卫生医学的未来作用。
Pub Date : 2002-12-01 DOI: 10.1093/pubmed/24.4.341
Geof Rayner
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引用次数: 0
期刊
Journal of public health medicine
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