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The role of autopsies in medical audit: examples from a department of medicine. 验尸在医疗审计中的作用:来自医学系的例子。
M Britton

Autopsy findings from a representative sample of deaths in a clinic provide an opportunity for regular and systematic revision of medical diagnostics and treatment. A standardized analysis of the collected results can furnish useful figures for comparisons and follow-up. On this basis, new strategies for future improvement of medical care should be outlined. Autopsy results can also be used for medical audit concerning more limited items like the certification of death.

从一个有代表性的诊所死亡样本中得出的尸检结果为定期和系统地修订医疗诊断和治疗提供了机会。对收集到的结果进行标准化分析可以为比较和后续工作提供有用的数据。在此基础上,应提出今后改善医疗保健的新战略。尸检结果也可以用于医疗审计,涉及更有限的项目,如死亡证明。
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引用次数: 9
The role of autopsy findings in multicenter treatment evaluations as exemplified by two aspirin trials. 尸检结果在多中心治疗评估中的作用,以两项阿司匹林试验为例。
M Britton

In many treatment trials the aim is to prevent deaths from one type of disease. The cause of death evaluation is therefore of the utmost importance. A high autopsy rate is required, even as regards sudden deaths that cannot routinely be referred to as ischemic heart disease. Autopsies are also necessary for studying non-lethal and lethal side effects of the involved drug. Even in the best of cases the post-mortem rate is far from 100% and correctness of the cause of death evaluation is not ensured. If the treatment has prevented deaths from the cause studied, this gain must not be outweighed by increases of other causes of death, for the result to be considered reliably positive.

在许多治疗试验中,目的是防止一种疾病导致的死亡。因此,死因评估至关重要。即使对于通常不能被称为缺血性心脏病的突然死亡,也需要很高的尸检率。尸检对于研究相关药物的非致命性和致命性副作用也是必要的。即使在最好的情况下,尸检率也远不是100%,死亡原因评估的正确性也不能得到保证。如果治疗预防了研究原因导致的死亡,那么这种增加不能被其他死亡原因的增加所抵消,这样的结果才能被认为是可靠的阳性结果。
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引用次数: 3
The reliability of autopsy diagnostics: inter-observer variation between pathologists, a preliminary report. 尸检诊断的可靠性:病理学家之间的观察者差异,初步报告。
B Veress, V Gadaleanu, I Nennesmo, B M Wikström

The aim of the study was to analyse the agreement between pathologists regarding macroscopic autopsy diagnostics. Four pathologists examined 35 autopsies and determined the principal disease and its complications, the immediate cause of death, other major diseases and their complications, and minor diseases. The participants were paired and their diagnoses were analysed by using kappa statistics for interobserver variation. The agreement on the principal disease was almost perfect between the participants (kappa values between 0.83 and 0.97), whereas that on the immediate cause of death was moderate/substantial (kappa values between 0.43-0.75). The list of all other major diseases and their complications was almost complete for each observer, but that of the minor diseases showed a more considerable variation. In spite of the high level of agreement it is recommended that the autopsy findings be discussed among pathologists if the clinical picture cannot be explained satisfactorily, and that the cause of death be determined by the clinicians after the demonstration of the autopsy.

该研究的目的是分析病理学家之间关于宏观尸检诊断的共识。4名病理学家检查了35具尸体,确定了主要疾病及其并发症、直接死亡原因、其他主要疾病及其并发症以及次要疾病。参与者被配对,他们的诊断用kappa统计分析观察者间变异。参与者对主要疾病的一致性几乎是完美的(kappa值在0.83和0.97之间),而对直接死亡原因的一致性是中等/主要的(kappa值在0.43-0.75之间)。所有其他主要疾病及其并发症的列表对每个观察者来说几乎都是完整的,但次要疾病的列表显示出更大的差异。尽管高度一致,但仍建议,如果临床图像不能令人满意地解释,则病理学家应讨论尸检结果,并由临床医生在尸检证明后确定死亡原因。
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引用次数: 14
The role of autopsy in cancer registration in Sweden, with special reference to findings in Malmö. 尸检在瑞典癌症登记中的作用,特别参考Malmö的发现。
N H Sternby

The role of a high autopsy frequency in the registration of cancer cases in a population was studied in the region of southern Sweden, in particular in Malmö. Due to a declining autopsy frequency the number of incidentally found cancer cases at autopsy has diminished greatly during the past 10 years. The value of the reports from cancer registries regarding the total number of tumours in a population is thus doubtful. In order to follow the real frequency of tumours, centres ought to be established where a high autopsy frequency can be achieved.

在瑞典南部地区,特别是Malmö,研究了高尸检频率在人口中癌症病例登记中的作用。由于尸检频率的下降,在尸检中偶然发现的癌症病例的数量在过去10年中大大减少。因此,癌症登记处关于人口中肿瘤总数的报告的价值值得怀疑。为了跟踪肿瘤的真实发生频率,应该在能够实现高解剖频率的地方建立中心。
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引用次数: 1
Autopsy and cause of death in randomized mammography studies. 随机乳腺x线摄影研究的尸检和死因
A Lindgren

Four randomized Swedish studies on the usefulness of mammography in screening for breast cancer have been published. The results have shown a variable but positive effect of screening in women more than 50 years of age but the effect is questionable before this age. The protocol and end points however differ between the studies and in order to summarize the results of the present studies, an unbiased, blinded end-point committee was created. The results of this study have been published recently. The present communication only concerns the role of autopsy in this study. The deaths of 1367 patients with a diagnosis of breast cancer have been studied. The percentage of autopsy varied from 21 to 74% between the four studies. When autopsy was performed, 58% were found to have died from breast cancer, 13% from other malignancies and the rest from other diseases. In cases with no autopsy, 73% were considered to have died of breast cancer and 9% of other malignancies. Deaths due to other cancers included a surprising number of cancers of the stomach, gallbladder and pancreas, two to three times higher than expected.

瑞典发表了四项关于乳房x光检查在乳腺癌筛查中的有效性的随机研究。结果显示,在50岁以上的女性中,筛查的效果是可变的,但却是积极的,但在这个年龄之前,效果是值得怀疑的。然而,研究方案和终点不同,为了总结目前研究的结果,成立了一个无偏见的盲法终点委员会。这项研究的结果最近发表了。目前的交流只涉及尸检在本研究中的作用。对1367名乳腺癌患者的死亡情况进行了研究。在这四项研究中,尸检的比例从21%到74%不等。在进行尸检时,发现58%的人死于乳腺癌,13%死于其他恶性肿瘤,其余死于其他疾病。在没有尸检的病例中,73%被认为死于乳腺癌,9%死于其他恶性肿瘤。其他癌症导致的死亡包括数量惊人的胃癌、胆囊癌和胰腺癌,比预期高出两到三倍。
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引用次数: 6
Quality requirements in nursing departments: development and use of a general framework. 护理部门的质量要求:总体框架的制定和使用。
G Visser, J de Bekker

The nursing staff of the Nijmegen University Hospital has implemented a project to formulate and evaluate objectives of quality of care. A quality profile, formulated on a national level, has been used as a guide in quality projects at nursing units for four years. The results of these quality projects show a lot of definite quality improvements and also a large number of quality requirements. In 1991 an inventory was made of these requirements. A specific method was used to select these requirements. Finally, a new framework of quality requirements was formulated. This framework offers the Nijmegen University Hospital possibilities such as: (i) being a source from which targets may be selected for quality improvement projects; (ii) requirements being made operational and used to measure the quality of nursing care.

奈梅亨大学医院的护理人员实施了一个项目,以制定和评估护理质量目标。在国家一级制定的质量概况已作为护理单位质量项目的指南使用了四年。这些质量工程的结果显示出许多明确的质量改进,也有大量的质量要求。1991年编制了一份这些需要的清单。使用了一种特定的方法来选择这些需求。最后,提出了一个新的质量需求框架。这一框架为奈梅亨大学医院提供了各种可能性,例如:(i)作为选择质量改进项目目标的来源;(ii)可操作的要求,并用于衡量护理质量。
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引用次数: 0
Design and results of the nursing quality assurance program in Hospital de la Santa Creu i Sant Pau: an integrated effort. 圣保罗圣克鲁医院护理质量保证项目的设计和结果:综合努力。
C Sanz, R Suñol, C Abelló, A Blanc

This paper aims to describe and evaluate the results of the Nursing Quality Assurance (QA) Program in the Hospital de la Santa Creu i Sant Pau. The program was designed in 1987 as part of a global QA program involving all aspects of patients' care. The QA Program was organized at three levels: hospital, ward and joint medical-nursing. During the first 3 years of the study the following activities were carried out: (A) nursing process and results; (B) risk management; (C) patients' opinion; (D) utilization review; (E) ward nursing QA programs. Among other significant results, the program has detected that only 55.6% patients manifest that they sleep well at hospital, hygiene of dependent males (51%) is significantly worse than dependent females (81%) and patients' falls are more prevalent among oriented patients (73%) than disoriented patients (27%). Also a significative improvement has been demonstrated after implementing corrective measures in patients' information (7.5/10-8.1/10) and patients without supervision in emergency areas became from 35% to 0.02%. New nursing records were designed as a result of the QA assessment. The most important conclusion is that the Nursing QA Program is a valid instrument to evaluate general problems in the hospital and concrete problems in each ward.

本文旨在描述和评估圣保罗圣克鲁医院护理质量保证(QA)计划的结果。该计划于1987年设计,是全球质量保证计划的一部分,涉及患者护理的各个方面。质量保证方案分为三个层次:医院、病房和联合医疗护理。在研究的前3年进行了以下活动:(A)护理过程和结果;(二)风险管理;(C)患者意见;(四)利用审查;(五)病房护理质量保证方案。在其他重要的结果中,该项目发现,只有55.6%的患者表示他们在医院睡得很好,受依赖的男性(51%)的卫生状况明显比受依赖的女性(81%)差,患者摔倒在定向患者中(73%)比迷失方向的患者(27%)更普遍。在患者信息(7.5/10-8.1/10)方面实施纠正措施后,也显示出显着改善,紧急区域无监护患者从35%降至0.02%。根据质量保证评估结果设计新的护理记录。最重要的结论是,护理质量保证程序是一个有效的工具,以评估医院的一般问题和具体问题,每个病房。
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引用次数: 1
Acute myocardial infarction: difference in the treatment between men and women. 急性心肌梗死:男女治疗差异。
M Dellborg, K Swedberg

During the last decade, treatment of myocardial infarction has changed and the prognosis dramatically improved. A sex bias in considering revascularization in men and women with coronary heart disease has been reported. The influence of gender on treatment given to patients with an acute myocardial infarction has not been investigated. From 1989 to 1991 there were 1515 patients with acute myocardial infarction admitted to the coronary care unit at Ostra Hospital; 67% were men. Pharmacological treatment limiting infarct size was given to 60% of all women and to 67% of all men; p < 0.05. In addition, coronary angiography during the hospital stay was performed in 0.2% of all women vs 1.9% of all men; p < 0.05. The prevalence of diabetes, age, symptoms or prehospital delay cannot explain these findings. While a sex bias in referring patients for revascularization has been reported, this report also describes a possible sex bias in the pharmacological treatment of acute myocardial infarction.

在过去的十年中,心肌梗死的治疗方法发生了变化,预后显著改善。有报道称,在考虑冠心病患者的血运重建术时存在性别偏见。性别对急性心肌梗死患者治疗的影响尚未调查。1989年至1991年,奥斯特拉医院冠心病监护室收治了1515例急性心肌梗死患者;67%为男性。60%的女性和67%的男性接受了限制梗死面积的药物治疗;P < 0.05。此外,住院期间进行冠状动脉造影的女性占0.2%,男性占1.9%;P < 0.05。糖尿病的患病率、年龄、症状或院前延迟不能解释这些发现。虽然在转诊患者进行血运重建术时存在性别偏见,但本报告也描述了在急性心肌梗死的药物治疗中可能存在的性别偏见。
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引用次数: 41
Perceived needs and patient satisfaction in relation to care provided in individuals with rheumatoid arthritis. 类风湿性关节炎患者对护理的感知需求和患者满意度。
P Bendtsen, P Bjurulf

A cross-sectional study was performed upon a group of patients (N = 222) with rheumatoid arthritis (RA), from a Swedish health care district. The aim was to elucidate expectations and satisfaction with health care workers. The participants indicated that a good reception is more important than professional knowledge followed by the ability to inform about RA and the ability to show empathy. There was a trend towards increasing satisfaction with information about medical problems with severity of RA. This stands in contrast to the lack of such a systematic relation with regard to increasing functional disability as measured by the Stanford Health Assessment Questionnaire. Reasons for this could be that the physicians tend to respond more to clinical signs than to daily living restrictions. A relatively high percentage (around 80%) of the patients were satisfied with the surgical procedures offered to them. Only one third of the individuals felt that they had been involved in planning of treatment and discharge although a majority expressed this as very important. The importance of a continuous dialogue between patient and physician with regard to fulfillment of patient expectations is emphasized.

横断面研究进行了一组患者(N = 222)与类风湿关节炎(RA),从瑞典卫生保健区。目的是阐明对卫生保健工作者的期望和满意度。参与者表示,良好的接待比专业知识更重要,其次是告知RA的能力和表达同情的能力。对风湿性关节炎严重程度的医疗问题信息的满意度有增加的趋势。这与斯坦福健康评估问卷所测量的功能性残疾增加缺乏这样的系统关系形成鲜明对比。造成这种情况的原因可能是医生倾向于对临床症状做出更多的反应,而不是对日常生活的限制。相对较高比例(约80%)的患者对提供给他们的手术程序感到满意。只有三分之一的人认为他们参与了治疗和出院的计划,尽管大多数人表示这非常重要。强调了患者和医生之间持续对话的重要性,以满足患者的期望。
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引用次数: 37
Complaint and disciplinary systems in dentistry in Sweden: a presentation and discussion of their efficacy in preventing malpractice. 投诉和纪律制度在牙科在瑞典:介绍和讨论他们的功效在防止医疗事故。
N René, P L Westesson, B Owall

The Swedish systems for complaints and supervision with many possibilities of claiming on different levels may lead to prevention of future problems in medical and dental care. The systems are corrective, preventive and compensatory, and are important in the process of quality assurance. However, some elements need improvement. The present paper gives as a background an overview of the Swedish systems and discusses a few cases. Comparisons with systems in other countries, especially the USA, are made, and new measures are discussed. There is a need for smooth, preventive measures as well as strong, punitive and corrective measures. Recidivist doctors/dentists must be stopped.

瑞典的投诉和监督制度有许多不同层次的索赔可能性,可以预防未来医疗和牙科保健方面的问题。这些系统具有纠正性、预防性和补偿性,在质量保证过程中起着重要作用。然而,有些元素需要改进。本文以瑞典制度的概况为背景,并讨论了几个案例。与其他国家,特别是美国的制度进行了比较,并讨论了新的措施。有必要采取顺利的预防性措施以及强有力的惩罚性和纠正性措施。必须制止再犯的医生/牙医。
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引用次数: 1
期刊
Quality assurance in health care : the official journal of the International Society for Quality Assurance in Health Care
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