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Comparison of dexmedetomidine and fentanyl as adjuvant to intrathecal levobupivacaine in lower segment cesarean section: A prospective, randomized double blind study 右美托咪定和芬太尼辅助下段剖宫产术鞘内左布比卡因的比较:一项前瞻性、随机双盲研究
IF 0.2 Q4 Medicine Pub Date : 2020-08-12 DOI: 10.35975/apic.v24i4.1309
Kapil Rastogi, A. Bharti, Y. Singh, P. Ranjan
Intrathecal Bupivacaine is most commonly used local anesthetic for lower segment cesarean section (LSCS) but there is constant endeavour for search of a local anesthetic (LA) which has improved safety profile for mother as well as foetus. So far many adjuvants like fentanyl, morphine or tramadol etc. has been used with intrathecal LA to prolong intraoperative anesthesia and postoperative analgesia.
鞘内布比卡因是下段剖宫产术(LSCS)中最常用的局部麻醉剂,但人们一直在努力寻找一种局部麻醉剂(LA),以提高母亲和胎儿的安全性。目前已有芬太尼、吗啡、曲马多等佐剂与鞘内LA联合使用,以延长术中麻醉和术后镇痛时间。
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引用次数: 1
Lisa J. Stearns, MD 丽莎·j·斯特恩斯,医学博士
IF 0.2 Q4 Medicine Pub Date : 2020-08-07 DOI: 10.35975/apic.v24i3.1294
T. Khan
Lisa Stearns, MD, Founder & Medical Director at Center for Pain and Supportive Care, Phoenix, USA, breathed her last on 31 May 2020 at her home in Mexico.As a physician, she was a valiant warrior. Her pursuit of novel methods, innovation, and creative approaches contributed widely to the practice of pain medicine globally. Courageous, stubbornly committed, and always compassionate, she was one of the heroes in the epidemic of pain and suffering.
Lisa Stearns,医学博士,美国凤凰城疼痛与支持护理中心创始人兼医学主任,于2020年5月31日在墨西哥的家中奄奄一息。作为一名医生,她是一名勇敢的战士。她对新方法、创新和创造性方法的追求为全球疼痛医学的实践做出了广泛贡献。她勇敢、坚定、富有同情心,是这场痛苦和苦难流行病中的英雄之一。
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引用次数: 0
Effect of dexmedetomidine as a sedative in sub-dural hematoma evacuation surgeries 右美托咪定在硬膜下血肿清除术中的镇静作用
IF 0.2 Q4 Medicine Pub Date : 2020-07-24 DOI: 10.35975/apic.v24i3.1302
S. B. Vasudevarao, K. Raja, Rammoorthi Rao
Background & objective: We studied the safety and effectiveness of combination of dexmedetomidine and fentanyl for chronic sub-dural hematoma (CSDH) evacuation. Main objectives of the study was to register the effects on the combination on the cardio-respiratory and analgesic outcome. Methodology: 56 patients with CSDH were divided into two group. Patients of Group A received dexmedetomidine 1 µg/kg over a period of 10 min with fentanyl 1 µg/kg, followed by an infusion of dexmedetomidine 0.3 µg/kg/min. Group B received fentanyl 1 µg/kg and midazolam 0.03 mg/kg IV. Sedation scores, hemodynamic changes and serial arterial blood gas (ABG) measurements were compared between the two groups. Results: Heart rate and diastolic blood pressure were significantly lower in Group A compared to Group B throughout the observation period after premedication. Systolic blood pressure readings was significantly lower in Group A compared to Group B from 10 min onwards till the end. ABG analysis showed that Group A had significantly lower PCO2 levels during and at the end of surgery and significantly higher PO2 at the end of procedure. Conclusion: The use of dexmedetomidine is associated with significantly higher PO2 at the end of the surgical procedure. It results in lower heart rate, systolic and diastolic blood pressures and PCO2 levels during and at the end of the subdural hematoma evacuation, but the fall remains within the physiological range.
背景与目的:我们研究了右美托咪定与芬太尼联合治疗慢性硬膜下血肿(CSDH)的安全性和有效性。本研究的主要目的是记录联合用药对心肺和镇痛效果的影响。方法:将56例CSDH患者分为两组。A组患者在10分钟内接受右美托咪定1µg/kg和芬太尼1µg/kg,然后输注0.3µg/kg/min。B组接受芬太尼1µg/kg和咪唑安定0.03 mg/kg IV。比较两组之间的镇静评分、血液动力学变化和系列动脉血气(ABG)测量值。结果:在用药前的整个观察期内,A组的心率和舒张压均显著低于B组。从10分钟开始到结束,A组的收缩压读数明显低于B组。ABG分析显示,A组在手术期间和手术结束时PCO2水平显著降低,在手术结束时PO2水平显著升高。结论:右美托咪定的使用与手术结束时PO2显著升高有关。在硬膜下血肿清除期间和结束时,它会降低心率、收缩压和舒张压以及PCO2水平,但下降幅度仍在生理范围内。
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引用次数: 0
The Anesthetist 的麻醉师
IF 0.2 Q4 Medicine Pub Date : 2020-07-15 DOI: 10.35975/apic.v24i3.1299
D. Sadaf
The pain is too much to bear But How come there is no tear With wounded heart and bleeding hands With teary eyes.. I treat u my dear
疼痛难忍,但为什么没有眼泪?受伤的心和流血的手,含泪的眼睛。。我待你亲爱的
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引用次数: 0
COVID-19 2019冠状病毒疾病
IF 0.2 Q4 Medicine Pub Date : 2020-07-15 DOI: 10.35975/apic.v24i3.1291
I. Yousuf, P. Bansal, Shivani Sharma
Novel corona virus disease, designated by WHO as COVID-19, took the world by storm. The brunt of the disease has to be borne by the respiratory system, although like any systemic disease, it affects almost every body organ system. The disease left us for too long a time wondering about its pathogenesis, and the best strategy to manage it regarding physical support as well as the pharmacotherapeutics.
被世界卫生组织命名为新冠肺炎的新型冠状病毒疾病席卷全球。这种疾病的主要负担必须由呼吸系统承担,尽管与任何系统性疾病一样,它几乎影响到每个身体器官系统。这种疾病让我们很长一段时间都在想它的发病机制,以及在物理支持和药物治疗方面管理它的最佳策略。
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引用次数: 0
Enhanced recovery after surgery (ERAS) in clinical practice 在临床实践中增强术后恢复(ERAS)
IF 0.2 Q4 Medicine Pub Date : 2020-07-15 DOI: 10.35975/apic.v24i3.1287
R. Leger, Jon Livelsberger, A. Sinha
‘Enhanced Recovery After Surgery’ (ERAS) protocols are an evidence-based, multidisciplinary system for patient care that— since its emergence in 2001— has shown remarkable efficacy in reducing surgical complications, shortening length of stay (LoS), and the incidence of hospital re-admission. Unfortunately, wide spread acceptance of ERAS has been slow, as it conflicts with some traditional perioperative care practices. However, with protocol compliance >70%, studies have shown significant reduction in mortality and postsurgical complications, with 30-50% reduction in LoS and approximately a 50% reduction in complications.
“术后增强恢复”(ERAS)方案是一种基于证据的多学科患者护理系统,自2001年出现以来,在减少手术并发症、缩短住院时间和再次入院的发生率方面表现出了显著的疗效。不幸的是,ERAS的广泛接受一直很慢,因为它与一些传统的围手术期护理实践相冲突。然而,在方案依从性>70%的情况下,研究表明死亡率和术后并发症显著降低,LoS降低30-50%,并发症降低约50%。
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引用次数: 1
Correlation of nasopharyngeal temperature with transcutaneous carotid artery temperature of adult patients under general anesthesia in rural tertiary care hospital. 农村三甲医院成人全麻患者鼻咽温度与经皮颈动脉温度的相关性研究。
IF 0.2 Q4 Medicine Pub Date : 2020-07-15 DOI: 10.35975/apic.v24i3.1284
A. Shetti, Bhavika Singla
Intraoperative temperature management is one of the important aspects in successful outcome of the surgical patient. Both anesthesia and surgery significantly have an impact on internal thermoregulation of the human body. We conducted this study to correlate nasopharyngeal temperature with transcutaneous carotid artery temperature of adult patients under general anesthesia (GA) in our rural institution.
术中体温管理是影响手术患者预后的重要因素之一。麻醉和手术对人体内部体温调节都有显著的影响。我们进行了这项研究的鼻咽温度与经皮颈动脉温度在我们的农村机构的成人病人全身麻醉(GA)。
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引用次数: 0
Tele-education in the post-COVID period; a new normal 新冠疫情后时期的远程教育;新常态
IF 0.2 Q4 Medicine Pub Date : 2020-07-14 DOI: 10.35975/apic.v24i3.1274
Z. Furqan, S. Fatima, G. A. Awan
Ischemia-reperfusion injury is a complex, which causes cell damage. In this study, we aimed to investigate the protective effects of dexmedetomidine on lung in the renal IR model in diabetic rats. The concept of tele-education has been present in the background for many years. From the idea of making use of your idle time by distant learning through television to use of simulated courses to enhance your clinical skills and judgements, tele-education has stood the test of time by constantly evolving according to the needs of modern era.
缺血再灌注损伤是一种复杂的细胞损伤。本研究旨在探讨右美托咪定对糖尿病大鼠肾IR模型肺的保护作用。远程教育的概念已经在背景中存在了很多年。从利用你的空闲时间通过电视远程学习的想法到利用模拟课程来提高你的临床技能和判断能力,远程教育根据现代时代的需要不断发展,经受住了时间的考验。
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引用次数: 5
Propofol infusion Syndrome 异丙酚输注综合征
IF 0.2 Q4 Medicine Pub Date : 2020-06-24 DOI: 10.35975/apic.v24i2.1265
S. Hasan
I am writing in order to stress upon the correct and safe rate of propofol infusion in intensive care unit (ICU) as a high rate of infusion can easily be missed and can lead to serious consequences. Propofol infusion syndrome (PRIS) is a well-known entity, which has been reported in both children and adults and is related to its high rates. First death due to PRIS was reported in 1990. The term was originally coined in 1998 by Bray to describe the adverse effects with its use in pediatric population. Though the first case was reported in a child, it has now been increasingly reported in adult ICU patients too.
我写这篇文章是为了强调在重症监护室(ICU)输注丙泊酚的正确和安全率,因为高输注率很容易被错过,并可能导致严重后果。异丙酚输注综合征(PRIS)是一种众所周知的疾病,在儿童和成人中都有报道,并与其高发病率有关。1990年报告了第一例PRIS死亡病例。该术语最初由Bray于1998年创造,用于描述其在儿科人群中的不良反应。尽管第一例病例是在儿童身上报告的,但现在在成人重症监护室患者中也有越来越多的报告。
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引用次数: 0
Anesthetic management of a child with methylmalonic acidemia for lens aspiration – a case report 一例儿童甲基丙二酸血症晶状体抽吸的麻醉处理
IF 0.2 Q4 Medicine Pub Date : 2020-06-24 DOI: 10.35975/apic.v24i2.1262
A. Huda, Mohammad Yasir
We report a case of a child with methylmalonic acidemia who presented to our hospital for lens aspiration surgery. Methylmalonic acidemia is an inherited disorder of protein catabolism. Its clinical effects can vary from mild to severe, and include lethargy, vomiting, hypotonia, hypothermia, failure to thrive and encephalopathy. The main concern in treatment of these patients is prevention of academia by identifying precipitating factors. It is especially important to acutely manage fluids and electrolytes before, during and after surgery.
我们报告了一个患有甲基丙二酸血症的儿童到我们医院接受晶状体抽吸手术的病例。甲基丙二酸血症是一种遗传性蛋白质分解代谢障碍。其临床效果从轻微到严重不等,包括嗜睡、呕吐、肌张力低下、体温过低、发育不良和脑病。治疗这些患者的主要关注点是通过识别诱发因素来预防学术界。在手术前、手术中和手术后对液体和电解质进行急性管理尤为重要。
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引用次数: 0
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