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MICROBIAL LANDSCAPE OF THE NEONATAL INTENSIVE CARE UNIT: A RETROSPECTIVE ANALYSIS 新生儿重症监护病房的微生物景观:回顾性分析
IF 0.2 Q4 Medicine Pub Date : 2021-03-31 DOI: 10.25284/2519-2078.1(94).2021.230608
D. Surkov, O. Kapustina
Objective. To investigate the structure, antenatal and intranatal risk factors and results of treatment of neonatal sepsis.Materials and methods. This study used analysis of 137 case histories of newborns from 2015 to 2019. We evaluated maternal risk factors, intrapartum asphyxia, duration of treatment, number of days on mechanical ventilation, the presence of sepsis, necrotic enterocolitis, mortality.Results and discussion. Most children were over 2500 g (69.3%). In infants with a birth weight lower than 1500 g were 10.9%. 70.8% of newborns received in the first 24 hours after birth. From the moment of admission to the department, among all infected children was 71%, mortality was 14%. In children under 29 weeks of gestation, the risk of developing sepsis is 17.2 times higher. (р˂0.001) In children under 1 kg of weight, the risk of manifestation of sepsis is 42.2 times higher. (р˂0.001)The maternal colonization have the risk of developing a child’s infection is 4.36 times higher. (р˂0.001)With a diagnosis of sepsis most infants were more than 2.5 kg and mortality remained significantly high 31.6-36.8% in all weight groups (0.00001), depending on birth weight.The majority of the applicants were children over 37 weeks, but mortality was significantly higher in the group from 29-37 weeks (0.00001), depending on the term of gestation.Among the studied mothers, up to 53% were maternal colonization and in this group the mortality of children was significantly higher than 23% (p=0.020).However, in the group of children where there were signs of ascending infection of the placenta (there were 25%) mortality was still significantly higher by 1.4 times, 32% (p=0,008).Conclusions. The risk of developing neonatal sepsis was increased in ascending infection (clinical chorioamnionitis) in 6.65 times, (р˂0.001), the presence of a coagulase-negative culture by 5.83 (р˂0.011) and invasive respiratory therapy by 18.52 times. (р˂0.002) Mortality rates are affected by gestational age OR=13.81 (р˂0.001), birth weight 1-1.5 kg OR=13.15 (р˂0.001), 1.5-2.5 kg OR=2.86 (р=0.043), maternal factors (vaginal colonization, ascending infection) OR=3,22 (р˂0.023), infection of placental membranes OR=4,32 (р˂0.008), the presence of sepsis OR=15,56 (р˂0.001), necrotic enterocolitis OR=8,06 (р˂0.001) and CoNS OR=4,98 (р˂0.033).
目标。目的探讨新生儿脓毒症的结构、产前及产后危险因素及治疗效果。材料和方法。本研究分析了2015年至2019年137例新生儿的病史。我们评估了产妇的危险因素,分娩时窒息,治疗持续时间,机械通气天数,败血症的存在,坏死性小肠结肠炎,死亡率。结果和讨论。大多数儿童超过2500克(69.3%)。在出生体重低于1500克的婴儿中为10.9%。70.8%的新生儿在出生后24小时内接受治疗。从入院的那一刻起,在所有感染儿童中占71%,死亡率为14%。在妊娠29周以下的儿童中,患败血症的风险高出17.2倍。(r小于0.001)体重低于1公斤的儿童出现败血症的风险高出42.2倍。(r小于0.001)母体感染的风险是母体感染的4.36倍。根据出生体重的不同,诊断为败血症的婴儿大多数体重超过2.5 kg,死亡率仍然很高,在所有体重组中均为31.6-36.8%(0.00001)。大多数申请人是37周以上的儿童,但29-37周组的死亡率明显更高(0.00001),具体取决于妊娠期。在被研究的母亲中,高达53%的母亲定植,在这一组中,儿童死亡率显著高于23% (p=0.020)。然而,在有上升胎盘感染迹象的患儿组(25%),死亡率仍显著高于1.4倍,为32% (p=0,008)。上升感染(临床绒毛膜羊膜炎)发生新生儿败血症的风险增加了6.65倍(小于0.001),凝固酶阴性培养增加了5.83倍(小于0.011),有创呼吸治疗增加了18.52倍。死亡率受胎龄OR=13.81(小于0.001)、出生体重1-1.5 kg OR=13.15(小于0.001)、1.5-2.5 kg OR=2.86(小于0.043)、母体因素(阴道定菌、上升感染)OR=3,22(小于0.023)、胎盘膜感染OR=4,32(小于0.008)、脓毒症OR=15,56(小于0.001)、坏死性小肠结肠炎OR=8,06(小于0.001)和CoNS OR=4,98(小于0.033)的影响。
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引用次数: 0
Teamwork in chronic pain management and the way forward in low and middle-income countries 慢性疼痛管理的团队合作与中低收入国家的前进道路
IF 0.2 Q4 Medicine Pub Date : 2021-03-28 DOI: 10.35975/APIC.V25I2.1477
A. Siddiqui, Usman Bashir
Assessment and management of patients with chronic pain is a challenging task due to its complex multidimensional nature and biopsychosocial impact. It requires a collaborative effort by an interdisciplinary team. Evidence showed that in low and middle-income countries (LMICs), 33% patients among general adult population, and 56% of general elderly population, suffer from chronic painful conditions.  Women are more likely to report chronic pain than men. In this narrative review, we attempted to search published literature to know the status of assessment and management of patients with chronic pain in low resource countries and to know the most appropriate chronic pain management strategies used in developed countries. We used broad electronic database (January 2010- December 2020) through common search engines. Lack of trained pain physicians and staffs, lack of interest, empathy and lack of integrated multidisciplinary approach are some of the barriers to achieve teamwork in chronic pain management. Authors strongly recommend the need of further research in this area, improvement in training programs for physicians and nursing staff for proper pain assessment and management of patients with chronic pain in low resource countries. Key words: Chronic pain management; Teamwork; Low resource; Multidisciplinary team; Interdisciplinary approach; Low and middle-income countries Citation: Siddiqui AS, Usman B. Teamwork in chronic pain management and the way forward in low and middle-income countries. Anaesth pain intensive care 2021;25(2):229-235. DOI: 10.35975/apic.v25i2.1477 Received: 18 January 2021, Reviewed: 20 January, 10 February 2021, Accepted: 9 March 2021
慢性疼痛患者的评估和管理是一项具有挑战性的任务,因为其复杂的多维性质和生物-心理-社会影响。这需要跨学科团队的合作。有证据表明,在中低收入国家,33%的普通成年患者和56%的普通老年人患有慢性疼痛。女性比男性更容易报告慢性疼痛。在这篇叙述性综述中,我们试图检索已发表的文献,以了解低资源国家对慢性疼痛患者的评估和管理状况,并了解发达国家使用的最合适的慢性疼痛管理策略。我们通过常见的搜索引擎使用了广泛的电子数据库(2010年1月至2020年12月)。缺乏训练有素的疼痛医生和工作人员,缺乏兴趣、同理心,以及缺乏综合的多学科方法,是实现慢性疼痛管理团队合作的一些障碍。作者强烈建议需要在这一领域进行进一步研究,改进医生和护理人员的培训计划,以便在资源匮乏的国家对慢性疼痛患者进行适当的疼痛评估和管理。关键词:慢性疼痛管理;团队合作资源量低;多学科团队;跨学科方法;中低收入国家引文:Siddiqui AS,Usman B.慢性疼痛管理团队合作和中低收入国家的前进道路。2021年Anaesth疼痛重症监护;25(2):229-235。DOI:10.35975/apic.v25i2.1477收到日期:2021年1月18日,审核日期:2021 1月20日,2月10日,接受日期:2021 3月9日
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引用次数: 0
Pain estimation after coronary angiography based on vital signs by using artificial neural networks 基于生命体征的人工神经网络冠状动脉造影术后疼痛评估
IF 0.2 Q4 Medicine Pub Date : 2021-02-03 DOI: 10.35975/APIC.V25I1.1433
Mohammad Amin Younesieh Heravi, A. Gazerani, M. Yaghubi, Zakiehe A. Amini, P. Salimi, Zahra Z. Falahi
Background: Coronary angiography is gold standard method to diagnose coronary arteries diseases. The aim of this study was to estimate pain after coronary angiography based on vital signs for determining best position by using artificial neural networks ANN. Methodology: This study used a database containing 86 subjects that refer to angiography center. For each subject Vital signs were measured that included blood pressure, percent of blood oxygen saturation, heart rate, respiratory rate and temperature. The Numeric Rating scale (NRS) was used to determine pain intensity. The vital signs were the inputs and the pain value was the corresponding output. These data were applied to train the ANN in the learning process. The model was implemented in MATLAB software. The results of pain estimation were compared with the results of NRS method and the error rate was calculated. Results: The absolute error and error percentage between NRS method and the present method were 5.41 ± 2.63 mmHg, 4.09 ± 1.59%. The results indicated that the pain measurement by NRS method and pain value predicted with trained ANN differ by only less than 11%. It is obvious that the neural network prediction fit properly to the NRS results. Conclusion: The results of proposed method were closely in agreement with the results of the NRS. so this method can be suggested for reliving the pain and determining the best patient's position after the angiography procedure. Key words: Artificial neural network; Coronary angiography; Pain Citation: Heravi MAY, Yaghubi MS, Amini ZA, Salimi PS, Falahi ZZ, Gazerani AG. Pain estimation after coronary angiography based on vital signs by using artificial neural networks. Anaesth. pain intensive care 2021;25(1):27–32. DOI: 10.35975/apic.v25i1.1433 Received: 21 November 2020, Reviewed: 2 December 2020, Accepted: 12 December 2020
背景:冠状动脉造影是诊断冠状动脉疾病的金标准方法。本研究的目的是根据生命体征估计冠状动脉造影后的疼痛,以使用人工神经网络确定最佳位置。方法:本研究使用了一个包含86名受试者的数据库,这些受试者都是血管造影中心的受试者。测量每个受试者的生命体征,包括血压、血氧饱和度百分比、心率、呼吸频率和体温。数值评定量表(NRS)用于确定疼痛强度。生命体征是输入,疼痛值是相应的输出。这些数据被用于在学习过程中训练神经网络。该模型在MATLAB软件中实现。将疼痛估计的结果与NRS方法的结果进行比较,并计算误差率。结果:NRS方法与现有方法的绝对误差和误差百分比分别为5.41±2.63mmHg和4.09±1.59%。结果表明,NRS方法的疼痛测量与训练后的神经网络预测的疼痛值相差不到11%。很明显,神经网络预测与NRS结果拟合良好。结论:所提出的方法的结果与NRS的结果非常一致。因此该方法可用于缓解疼痛和确定血管造影术后患者的最佳位置。关键词:人工神经网络;冠状动脉造影;疼痛引文:Heravi MAY,Yaghubi MS,Amini ZA,Salimi PS,Falahi ZZ,Gazerani AG。使用人工神经网络基于生命体征的冠状动脉造影后疼痛估计。Anaesth。疼痛重症监护2021;25(1):27–32.DOI:10.35975/apic.v25i.1433接收日期:2020年11月21日,审核日期:2020月2日,接受日期:2020 12月12日
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引用次数: 0
Optimizing training programs and opportunities for professional development in the era of digital pain interventions: A unique opportunity for collaboration 优化数字疼痛干预时代的培训计划和专业发展机会:一个独特的合作机会
IF 0.2 Q4 Medicine Pub Date : 2021-01-26 DOI: 10.35975/APIC.V25I1.1444
H. MahmoodSyed, Amara Nasir
Introduction: New digital health technologies provide accessible adjuncts to alleviating pain in the general population. The advent novel digital pain interventions have resulted in a rapidly evolving learning environment. Improving knowledge and understanding of these digital patient-centric approaches to treating pain is vital for our current practitioners and new cadre of trainees. The objective of this manuscript is to initiate a discussion about digital pain intervention educational needs of residents as well as attendings in PM&R, anesthesia and neurology. Methodology: After reviewing Accreditation Council Graduate Medical Education (ACGME) and relevant American Board of Medical Specialties policies and best available evidence, including grey literature, we interviewed a group of practicing physicians in physiatry, anesthesiology and neurology, including program directors, to provide expert opinion, guidance and formulate recommendations on educational requirements, research endeavors, and learning techniques and opportunities in utilizing digital health interventions for management of pain. IRB approval was not required. Conclusions: We hope that this manuscript will serve as the basis of designing a comprehensive educational program and outlining opportunities for research that prioritizes optimal care for pain patients and leverages the unique and complementary knowledge base within our fields. Key words: Digital pain; Physiatry; anesthesiology; Neurology; Competency; Accreditation Council Graduate Medical education Citation: Nasir A, Mahmood SH. Optimizing training programs and opportunities for professional development in the era of digital pain interventions: A unique opportunity for collaboration. Anaesth. pain intensive care 2021;25(1): 76–80. D0I: 10.35975/apic.v25i1.1444 Received: 24 October 2020; Reviewed: 22 November 2020; Accepted: 5 December 2020
简介:新的数字健康技术为缓解普通人群的疼痛提供了可获得的辅助手段。新型数字疼痛干预措施的出现带来了一个快速发展的学习环境。提高对这些以数字患者为中心的疼痛治疗方法的知识和理解,对我们现有的从业者和新的受训人员至关重要。这篇手稿的目的是引发一场关于住院医师数字疼痛干预教育需求以及PM&R、麻醉和神经病学的讨论。方法:在审查了认证委员会研究生医学教育(ACGME)和美国医学专业委员会的相关政策和最佳可用证据(包括灰色文献)后,我们采访了一组物理、麻醉学和神经病学的执业医生,包括项目主任,以提供专家意见,指导并制定关于利用数字健康干预措施管理疼痛的教育要求、研究努力、学习技术和机会的建议。不需要IRB批准。结论:我们希望这份手稿将成为设计一个全面教育计划的基础,并概述优先考虑疼痛患者最佳护理的研究机会,并利用我们领域内独特和互补的知识库。关键词:数字疼痛;生理学;麻醉学;神经学能力;认证委员会研究生医学教育引文:Nasir A,Mahmood SH.在数字疼痛干预时代优化培训计划和专业发展机会:一个独特的合作机会。Anaesth。疼痛重症监护2021;25(1):76–80。D0I:10.35975/apic.v25i.1444收到时间:2020年10月24日;审核日期:2020年11月22日;接受日期:2020年12月5日
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引用次数: 0
The effect of mother’s voice on pain and physiological parameters during arterial blood sampling in children hospitalized in PICUs PICU住院儿童动脉采血时母亲声音对疼痛和生理参数的影响
IF 0.2 Q4 Medicine Pub Date : 2021-01-24 DOI: 10.35975/APIC.V25I1.1440
M. Shoghi, M. Ahmadi, Mahboubeh Rasouli
Introduction: Arterial blood sampling is a painful procedure, and is frequently performed in PICUs. Listening to mother's voice may be effective in reducing pain during arterial blood sampling in children. This study was aimed to determine the effect of mother’s recorded voice on pain and physiological parameters during arterial blood sampling in children hospitalized in PICUs. Methodology: This study was a single blind randomized clinical trial with crossover design. Fifty children hospitalized in PICUs participated in this study. The participants were selected through “sequential sampling” and randomly allocated into two groups; e.g., Group AB (n = 25) and Group BA (n = 25). Physiological parameters and pain in each child were measured before and during arterial blood sampling with (B) and without (A) listening to their mothers’ voices with a minimum of 24 hrs interval. To measure the pain, COMFORT pain scale was used and the physiological parameters were measured using the monitoring devices connected to the children. Data were analyzed with SPSS version 22, repeated measure test, paired and non-paired t-test, Wilcoxon and Mann-Whitney test. Results: Means of pain scores and physiologic parameters did not show a significant difference before the intervention on the first and second day between the two groups (AB-BA). The results showed the period effect (f = 0.581 and p = 0.89) and carry over effect (f = 0.055, p-value = 0.881) were not significant. Results of paired t-test showed that the mean pain score during arterial blood sampling with (B: 21.82 ± 5.53) and without (A: 22.40 ± 4.76) listening to their mothers’ voices was significantly different (p = 0.002). That is, with the mother’s voice, the children felt a lower level of pain. The SpO2 decline during the sampling was less with the mother’s voice. Additionally, the heart rate declined less during the sampling compared to the rate before the sampling with the mother’s voice; still, the difference was not significant (p > 0.05). Conclusion: Listening to mothers’ recorded voice was effective to alleviate pain during arterial blood sampling in children hospitalized in PICUs. The use of this method to reduce pain during this painful procedure is effective even in the absence of the mother. Key words: Pain; Mother’s voice; Arterial blood sampling; Physiological indices; PICU Citation: Shoghi M, Ahmadi M, Rasouli M. The effect of mother’s voice on pain and physiological parameters during arterial blood sampling in children hospitalized in PICUs. Anaesth. pain intensive care 2021;25(1):40-47.DOI: 10.35975/apic.v25i1.1440  Received: 20 June 2020, Reviewed: 16 September 2020, Accepted: 25 November 2020
动脉采血是一个痛苦的过程,经常在picu中进行。倾听母亲的声音可能有效地减轻儿童动脉采血时的疼痛。本研究旨在确定母亲录音对picu住院儿童动脉采血期间疼痛和生理参数的影响。方法:本研究为单盲随机临床试验,采用交叉设计。50名picu住院儿童参与了本研究。通过“序贯抽样”的方式选择参与者,随机分为两组;例如,AB组(n = 25)和BA组(n = 25)。在(B)和(A)不听母亲声音的情况下,每个孩子在动脉采血前和采血过程中测量生理参数和疼痛,间隔至少24小时。疼痛测量采用COMFORT疼痛量表,生理参数测量采用连接患儿的监测装置。数据分析采用SPSS 22、重复测量检验、配对和非配对t检验、Wilcoxon和Mann-Whitney检验。结果:两组患者干预前第1天、第2天的疼痛评分和生理参数平均值(AB-BA)无显著差异。结果显示,周期效应(f = 0.581, p = 0.89)和结转效应(f = 0.055, p值= 0.881)均不显著。配对t检验结果显示,倾听母亲声音组(B: 21.82±5.53)与未倾听母亲声音组(A: 22.40±4.76)动脉采血时平均疼痛评分差异有统计学意义(p = 0.002)。也就是说,当听到母亲的声音时,孩子们感受到的疼痛程度较低。在采样过程中,SpO2随母亲声音的下降幅度较小。此外,与母亲声音采样前相比,采样期间的心率下降幅度较小;但差异无统计学意义(p < 0.05)。结论:聆听母亲录音可有效减轻picu住院患儿动脉采血时的疼痛。在这个痛苦的过程中,使用这种方法来减轻疼痛,即使在母亲不在的情况下也是有效的。关键词:疼痛;母亲的声音;动脉采血;生理指标;引用本文:Shoghi M, Ahmadi M, Rasouli M.母亲声音对PICU住院儿童动脉采血过程中疼痛和生理参数的影响。Anaesth。疼痛重症监护2021;25(1):40-47。收稿日期:2020年6月20日,审稿日期:2020年9月16日,录用日期:2020年11月25日
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引用次数: 2
Ivermectin for COVID-19;to use or not to use? 伊维菌素治疗COVID-19:使用还是不使用?
IF 0.2 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.35975/apic.v25i5.1651
Y. Morimoto
COVID-19 has engulfed the continents into a pandemic, filling the hospitals with this viral disease, heavily taxing the healthcare facilities and claiming thousands of lives in almost every country. In the absence of a known evidence based remedy, many treatment options have been tried with variable results. Multiple vaccines have been developed by the drug industry, but none can be claimed to be 100% effective in prevention of the disease. There has been some evidence about the beneficial effects of ivermectin - an anthelmintic drug. This editorial discusses the various aspects of the use of ivermectin for the treatment of active COVID-19.
COVID-19席卷了各大洲,使其成为一场大流行,这种病毒性疾病使医院人满为患,给医疗机构造成沉重负担,几乎在每个国家都夺去了数千人的生命。在缺乏已知的基于证据的补救措施的情况下,已经尝试了许多治疗方案,结果不一。制药行业已经开发了多种疫苗,但没有一种疫苗可以声称100%有效地预防这种疾病。有一些证据表明伊维菌素——一种驱虫药的有益作用。这篇社论讨论了使用伊维菌素治疗活动性COVID-19的各个方面。
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引用次数: 0
Acute kidney injury in COVID-19: A single-center experience in Nigeria COVID-19中的急性肾损伤:尼日利亚的单中心经验
IF 0.2 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.35975/apic.v25i4.1567
Olayinka Rasheed Ibrahim, T. Oloyede, H. Gbadamosi, Y. Musa, R. Aliu, S. Bello, M. Alao, B. Suleiman, O. Adedoyin
Background & objective: Despite available data from developed countries, suggesting a high incidence of acute kidney injury (AKI) in coronavirus disease 2019 (COVID-19), there is scarce data from African countries, including Nigeria. We conducted this study to determine and document the incidence, the associated factors and the outcome (in-hospital mortality) of AKI among COVID-19 patients managed in a center in Nigeria. Methodology: It was a retrospective review of confirmed COVID-19 cases managed at a center in Nigeria. AKI was defined using 2012 Kidney Disease: Improving Global Outcomes (KDIGO) creatinine criteria. We extracted relevant data from the electronic records of the COVID-19 patients admitted to our hospital and analyzed. Fischer's exact tests were used to test factors associated with AKI for discrete variables, Mann-Whitney U test was used for skewed continuous data, and T-test for continuous normal distribution variables. Results: This study involved 41 of the 56 confirmed COVID-19 cases. The mean age was 45 +/- 17.94 y. A majority of the patients were males (33;80.5%). AKI occurred in 6 (14.6%) of the patients. Of the 6 AKI;4 (66.7%) and 2 (33.3%) were in stages 1 and 3 respectively. One patient (16.7%) had had hemodialysis. Of the 6 with AKI, 3 died with a mortality rate of 50.0%. Factors associated with AKI included age above 45 years, body weakness, severe and critical COVID, urea > 10 mmol/l, and serum creatinine > 1.5 mg/dl. Only severe and critical disease was predictive of AKI (adjusted odds ratio 1.777, 95% CI 1.028, 3.074). Conclusion: The results of our study show that AKI is common in severe and critical COVID-19 and is associated with a poor outcome.
背景与目的:尽管来自发达国家的现有数据表明,2019年冠状病毒病(COVID-19)中急性肾损伤(AKI)的发生率很高,但来自包括尼日利亚在内的非洲国家的数据很少。我们进行了这项研究,以确定和记录尼日利亚一家中心管理的COVID-19患者的AKI发病率、相关因素和结果(院内死亡率)。方法:对尼日利亚一个中心管理的COVID-19确诊病例进行回顾性审查。AKI的定义采用2012肾脏疾病:改善全球预后(KDIGO)肌酐标准。我们从我院收治的COVID-19患者电子病历中提取相关数据进行分析。离散变量使用Fischer精确检验来检验与AKI相关的因素,偏态连续数据使用Mann-Whitney U检验,连续正态分布变量使用t检验。结果:本研究涉及56例新冠肺炎确诊病例中的41例。平均年龄45±17.94岁,男性居多(33;80.5%)。6例(14.6%)患者发生AKI。6例AKI患者中,分别有4例(66.7%)和2例(33.3%)处于1期和3期。1例患者(16.7%)曾做过血液透析。6例AKI患者中,3例死亡,死亡率为50.0%。与AKI相关的因素包括年龄大于45岁、身体虚弱、重症和危重型COVID、尿素> 10 mmol/l、血清肌酐> 1.5 mg/dl。只有重症和危重症可预测AKI(校正优势比1.777,95% CI 1.028, 3.074)。结论:我们的研究结果表明,AKI在重症和危重型COVID-19中很常见,并与不良预后相关。
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引用次数: 1
Anesthesiologist as a perioperative physician, clinician, administrator, educator, and a researcher 麻醉师作为围手术期医师、临床医师、管理人员、教育工作者和研究人员
IF 0.2 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.35975/apic.v25i5.1649
K. Shibli, S. Shibli
Anesthesia is an acute care specialty with a much wider scope in the current clinical practice. The addition of new clinical subspecialties puts additional pressure on already demanding workload with limited global anesthesia workforce. Doctors' burnout reports and currently exhausted doctors struggling with their clinical duties during COVID-19 pandemic are ample evidence of it. Due to COVID-19 crisis, a lot of subspecialty crossover care is provided by the anesthetists, and they have to work outside their normal clinical comfort zones. Anesthesiologists have been entrusted with the responsibilities of perioperative physicians in the last two decades. An anesthesiologist has to adopt several roles in a healthcare institution, including 'administrative', 'academic', 'clinical' and 'research' attributes. An ideal anesthesiologist is expected to have a fine blend of all of these traits, though the proportion of each will vary according to the work environment and the personal choices and preferences.
麻醉是目前临床应用范围较广的急症专科。新的临床亚专科的增加增加了全球麻醉劳动力有限的工作量的额外压力。医生的倦怠报告以及目前在COVID-19大流行期间努力履行临床职责的疲惫医生都是充分的证据。由于新冠肺炎危机,许多亚专科交叉护理由麻醉师提供,他们不得不在正常的临床舒适区之外工作。在过去的二十年里,麻醉师被赋予了围手术期医生的责任。麻醉师必须在医疗机构中扮演多个角色,包括“行政”、“学术”、“临床”和“研究”属性。一个理想的麻醉师应该是所有这些特质的完美结合,尽管每一种特质的比例会根据工作环境和个人选择和偏好而有所不同。
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引用次数: 2
Case fatality rate and survival functions of severe COVID-19 patients in intensive care unit of Bangabandhu Sheikh Mujib Medical University in Bangladesh: an observational study 孟加拉国Bangabandhu Sheikh Mujib医科大学重症监护病房重症COVID-19患者病死率和生存功能的观察性研究
IF 0.2 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.35975/apic.v25i4.1553
M. S. Islam, D. Bhowmick, M. Parveen, M. Kamal, A. Akhtaruzzaman
Background: Emergence of current pandemic caused by novel SARS-COV-2 has already caused over 963000 deaths. Case fatality rate (CFR) estimation helps understanding the disease severity and the lethality trend, high risk population and subsequently, optimization of quality healthcare facilities. Our observational study aimed to find out existing trends in treating the most vulnerable group with scarce medical resource allocation and to implement necessary support services to comply with the ensuing need for best possible outcomes in our ICU. Methodology: In this observational study, all COVID-19 diagnosed patients admitted in our ICU from July 4, 2020 to September 22, 2020, were enrolled. Data were obtained from the core ICU register of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Information accumulated on predesigned data sheets comprised of particulars of patients, co-morbidities, duration of ICU stay, mode of oxygenation, organ support and quick SOFA scores. Total deaths in ICU (in hospital or referred from outside of BSMMU) were recorded. Results: The results revealed that all patients were either very severe or critically sick with COVID-19 pneumonia at the time of ICU admission. Out of 174 patients, 46 (26.44%) were put on invasive ventilation and the rest received noninvasive ventilation in the form of NRM, high flow nasal cannula (HFNC), continuous positive airway pressure (CPAP or BiPAP), CTEX CPAP and non-invasive ventilation (NIV) as appropriate. Male and female ratio was 74:26. Age of patients ranged between 19-95y. The median age of patients was 65 y (IQR: 57-70).Quick SOFA scores were more than 2 in 65.37% of patients. Regarding co-existing organ dysfunction 13.8% had 3 or more co-morbidities;while 74.1% had 2 and 9.8% had a single systemic illness along with COVID-19. Most common diseases encountered among 135 deceased were hypertension (64%), IHD (49%), diabetes mellitus (45%), bronchial asthma or COPD (32%), renal failure (either ARF or CRF) (20%). Overall CFR due to COVID-19 pneumonia associated with co-morbidities was 77.6%. Relatively higher CFR (82.6%) was evident harboring multi-organ dysfunction especially among COVID-19 patients aged 50y or more. Gender linked CFR were 81.4% and 66.7% in males and females respectively. Conclusion: High CFR demonstrates significant correlation with increasing age and co-morbidities and survival functions. Late presentation to the hospital and invasive mechanical ventilation also contributed to high CFR.
背景:由新型SARS-COV-2引起的当前大流行的出现已经造成96.3万多人死亡。病死率(CFR)估计有助于了解疾病严重程度和死亡趋势、高危人群以及随后优化优质医疗保健设施。我们的观察性研究旨在发现在医疗资源分配稀缺的情况下,治疗最弱势群体的现有趋势,并实施必要的支持服务,以满足ICU对最佳可能结果的后续需求。方法:本观察性研究纳入2020年7月4日至2020年9月22日在我院ICU收治的所有COVID-19确诊患者。数据来自孟加拉国达卡的Bangabandhu Sheikh Mujib医科大学(BSMMU)核心ICU登记册。收集在预先设计的数据表上的信息包括患者的详细情况、合并症、ICU住院时间、氧合方式、器官支持和快速SOFA评分。记录了ICU(住院或从BSMMU以外转诊)的总死亡人数。结果:所有患者入ICU时均为COVID-19肺炎重症或危重症患者。在174例患者中,46例(26.44%)患者采用有创通气,其余患者根据需要采用无创通气方式,包括NRM、高流量鼻插管(HFNC)、持续气道正压通气(CPAP或BiPAP)、CTEX CPAP和无创通气(NIV)。男女比例为74:26。患者年龄19-95岁。患者中位年龄为65岁(IQR: 57-70)。65.37%的患者快速SOFA评分大于2分。在共存器官功能障碍方面,13.8%的人有3种及以上合并症,74.1%的人有2种或更多合并症,9.8%的人有单一的系统性疾病并伴有COVID-19。135名死者中最常见的疾病是高血压(64%)、IHD(49%)、糖尿病(45%)、支气管哮喘或慢性阻塞性肺病(32%)、肾衰竭(ARF或CRF)(20%)。与合并症相关的COVID-19肺炎的总CFR为77.6%。伴有多器官功能障碍的CFR相对较高(82.6%),尤其是50岁及以上的COVID-19患者。男性和女性的性别相关CFR分别为81.4%和66.7%。结论:高CFR与年龄增长、合并症和生存功能相关。晚到医院和有创机械通气也是导致高CFR的原因。
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引用次数: 1
The impact of corona pandemic on critical care medicine 冠状病毒大流行对重症监护医学的影响
IF 0.2 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.35975/apic.v25i4.1563
Faraz Mansoor
Y A pandemic is defined as an epidemic of an infectious etiology that crosses the international boundaries and infects a large number of people. This has happened several times in the human history;influenza, smallpox, bubonic plaque and cholera being some of the examples. Smallpox alone has resulted in death of 300-500 million people. As a frontline healthcare professional fighting against the COVID-19 pandemic, the author has experienced its socioeconomic and psychological consequences. In addition, critical care units faced ethical challenges to meet with the bed requirement. Dedicated and modified COVID-19 critical care services were started in both the public and private sectors. Because of high workload and lack of trained medical and nursing staff, extra staff ha to be recruited on temporary basis. Some commonly performed procedures were modified to decrease the risk of infection spread. ICUs faced shortage of personal protective equipment and ventilators. Training programs were developed to help improve the understanding of novel COVID-19 infection. ICU staff was probably at lower risk of acquiring this infection as compared to other hospital staff.
Y .大流行的定义是一种具有传染性的流行病,它跨越了国际边界,感染了大量的人。这种情况在人类历史上发生过几次,流感、天花、淋巴腺斑块和霍乱就是其中的一些例子。光是天花就造成3 -5亿人死亡。作为抗击新冠肺炎疫情的一线医护人员,笔者亲身经历了疫情带来的社会经济和心理后果。此外,重症监护病房在满足床位需求方面面临道德挑战。在公共和私营部门都启动了专门和改进的COVID-19重症监护服务。由于工作量大,缺乏训练有素的医务和护理人员,必须临时征聘额外的工作人员。一些常用的手术被修改以降低感染传播的风险。重症监护室面临个人防护装备和呼吸机短缺的问题。制定了培训计划,以帮助提高对新型COVID-19感染的了解。与其他医院工作人员相比,ICU工作人员获得这种感染的风险可能较低。
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引用次数: 1
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Anaesthesia, Pain & Intensive Care
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