Pub Date : 1998-07-01DOI: 10.1590/S0103-06631998000300005
D. L. Campos, Débora Gonçalves de Farias, O. A. Toledo, A. Bezerra
An epidemiologic study was conducted to evaluate the prevalence of dental fluorosis in Brasilia - Federal District, a community where fluoride concentration is 0.8 ppm in drinking water. The sample consisted of 833 school children of both sexes, aged between 8 and 12, who have been living in Brasilia since birth. The anterior upper permanent teeth were examined and HOROWITZ fluorosis index was applied to evaluate pathological occurrences. No sex differences were observed in dental fluorosis prevalence. The authors found a high number of dental fluorosis free children (85.36%) and 14.64% of the sample showed light and moderate levels of fluorosis.
{"title":"Prevalência de fluorose dentária em escolares de Brasília - Distrito Federal","authors":"D. L. Campos, Débora Gonçalves de Farias, O. A. Toledo, A. Bezerra","doi":"10.1590/S0103-06631998000300005","DOIUrl":"https://doi.org/10.1590/S0103-06631998000300005","url":null,"abstract":"An epidemiologic study was conducted to evaluate the prevalence of dental fluorosis in Brasilia - Federal District, a community where fluoride concentration is 0.8 ppm in drinking water. The sample consisted of 833 school children of both sexes, aged between 8 and 12, who have been living in Brasilia since birth. The anterior upper permanent teeth were examined and HOROWITZ fluorosis index was applied to evaluate pathological occurrences. No sex differences were observed in dental fluorosis prevalence. The authors found a high number of dental fluorosis free children (85.36%) and 14.64% of the sample showed light and moderate levels of fluorosis.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"51 1","pages":"225-230"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-07-01DOI: 10.1590/S0103-06631998000300011
Marco Antônio Meloncini, Paulo Eduardo dos Reis Cardoso, Rosa Helena Miranda Grande, A. Muench
The purpose of this research was to study the frequency of retention loss of removable partial denture clasps. Loss of retention was determined after several cycling periods (initially zero, and 1, 5, 15 and 25 thousand). Frequency was based on the number of vacant spaces when the clasp failed by rupture or retention loss under 120g. Thus, the number of vacant spaces depends on the number of clasps fractured and/or that lost retention. Other variables were: four base metal alloys, two types of clasps (standard and extra, which was thinner), and two teeth (premolar and molar). The conclusions were that: the number of vacant spaces depends on alloys with or without adjustment; with adjustment the extra clasp presented less failures; frequency of clasp failures is very high and almost half occurred up to 1,000 cycles.
{"title":"Falhas de grampos circunferenciais de próteses removíveis em função de ciclagens de flexão","authors":"Marco Antônio Meloncini, Paulo Eduardo dos Reis Cardoso, Rosa Helena Miranda Grande, A. Muench","doi":"10.1590/S0103-06631998000300011","DOIUrl":"https://doi.org/10.1590/S0103-06631998000300011","url":null,"abstract":"The purpose of this research was to study the frequency of retention loss of removable partial denture clasps. Loss of retention was determined after several cycling periods (initially zero, and 1, 5, 15 and 25 thousand). Frequency was based on the number of vacant spaces when the clasp failed by rupture or retention loss under 120g. Thus, the number of vacant spaces depends on the number of clasps fractured and/or that lost retention. Other variables were: four base metal alloys, two types of clasps (standard and extra, which was thinner), and two teeth (premolar and molar). The conclusions were that: the number of vacant spaces depends on alloys with or without adjustment; with adjustment the extra clasp presented less failures; frequency of clasp failures is very high and almost half occurred up to 1,000 cycles.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"257-260"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-07-01DOI: 10.1590/S0103-06631998000300004
M. Rocha, José Luciano Bezerra Moreira, D. Menezes, M. Cunha, C. B. Carvalho
Periapical tissue from 30 individuals requiring dental surgery was examined histologically and cultured for the presence of bacteria. A total of 137 strains of bacteria were isolated and of the isolates, 65.7% were strict anaerobes, 29.2%, facultative anaerobes and 5.1%, strict aerobes. Fusobacterium nucleatum was the species most frequently isolated, followed by pigmented strict anaerobes, Peptostreptococcus sp and Streptococcus mitis. In all cases more than one bacterial species was found. The histological analysis demonstrated prevalence of periapical granuloma. Fusobacterium nucleatum isolated from 16 patients was tested for susceptibility to penicillin, cefoxitin, erythromycin, metronidazole and tetracycline. All strains were susceptible to cefoxitin, metronidazole and tetracycline and the resistance rates to penicillin and erythromycin were 12.5 and 68.8% respectively. The resistance rates of F. nucleatum, an important bacterium in periapical infection to penicillin and erythromycin emphasize the need to further study antimicrobial resistance of bacteria isolated from odontogenic infections.
{"title":"Estudo bacteriológico de lesões periapicais","authors":"M. Rocha, José Luciano Bezerra Moreira, D. Menezes, M. Cunha, C. B. Carvalho","doi":"10.1590/S0103-06631998000300004","DOIUrl":"https://doi.org/10.1590/S0103-06631998000300004","url":null,"abstract":"Periapical tissue from 30 individuals requiring dental surgery was examined histologically and cultured for the presence of bacteria. A total of 137 strains of bacteria were isolated and of the isolates, 65.7% were strict anaerobes, 29.2%, facultative anaerobes and 5.1%, strict aerobes. Fusobacterium nucleatum was the species most frequently isolated, followed by pigmented strict anaerobes, Peptostreptococcus sp and Streptococcus mitis. In all cases more than one bacterial species was found. The histological analysis demonstrated prevalence of periapical granuloma. Fusobacterium nucleatum isolated from 16 patients was tested for susceptibility to penicillin, cefoxitin, erythromycin, metronidazole and tetracycline. All strains were susceptible to cefoxitin, metronidazole and tetracycline and the resistance rates to penicillin and erythromycin were 12.5 and 68.8% respectively. The resistance rates of F. nucleatum, an important bacterium in periapical infection to penicillin and erythromycin emphasize the need to further study antimicrobial resistance of bacteria isolated from odontogenic infections.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"38 1","pages":"215-223"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-07-01DOI: 10.1590/S0103-06631998000300018
E. Gonçalves, Sérgio Augusto Catanzaro Guimarães, Roberto Brandão Garcia
Research into the molecular initiators of bone development and repair has culminated in the identification of an entirely new family of proteins that regulate bone and cartilage formation in vivo. These proteins are known as bone morphogenetic proteins or BMPs and are capable of inducing bone formation when implanted into ectopic sites. The purification and characterization of BMPs, until recently an elusive goal, have laid the foundation for the cellular and molecular dissection of bone development and regeneration. BMPs, critical in the normal development of animals, may play multiple roles, not exclusively pertinent to bone tissue. This review aims to present a concise perspective of BMPs, and their potential role and application for regenerative procedures.
{"title":"Proteínas morfogenéticas ósseas: terapêutica molecular no processo de reparo tecidual","authors":"E. Gonçalves, Sérgio Augusto Catanzaro Guimarães, Roberto Brandão Garcia","doi":"10.1590/S0103-06631998000300018","DOIUrl":"https://doi.org/10.1590/S0103-06631998000300018","url":null,"abstract":"Research into the molecular initiators of bone development and repair has culminated in the identification of an entirely new family of proteins that regulate bone and cartilage formation in vivo. These proteins are known as bone morphogenetic proteins or BMPs and are capable of inducing bone formation when implanted into ectopic sites. The purification and characterization of BMPs, until recently an elusive goal, have laid the foundation for the cellular and molecular dissection of bone development and regeneration. BMPs, critical in the normal development of animals, may play multiple roles, not exclusively pertinent to bone tissue. This review aims to present a concise perspective of BMPs, and their potential role and application for regenerative procedures.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"299-304"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200004
A. B. Matos, M. L. Turbino, Edmir Matson
Procedures aiming at removing stains form teeth have been widely pursued. Among these procedures are the techniques of enamel microbrasion, which can produce more favorable esthetic results. The aim of this study was to compare the results obtained clinically with application of different microabrasion techniques on white spot lesions, and also to evaluate enamel roughness in treated and untreated specimens using scanning electron microscopy. Patients with white spot lesions without cavitation were selected. On the first patient a mechanically applied clinical procedure was performed, while on the second one the clinical procedure was performed manually, and impressions were taken at different steps of the procedure in order to obtain samples to be examined under the scanning electron microscope. From the obtained results, it could conclude that the microabrasion techniques carried out with phosphoric acid and pumice flour, either with rotatory instruments or applied manually with a wood wegde, presented clinically satisfactory results. Under the scanning electron microscope, restoring of the superficial smoothness of treated enamel could be observed.
{"title":"Efeito das técnicas de microabrasão no esmalte: estudo em microscopia eletrônica de varredura","authors":"A. B. Matos, M. L. Turbino, Edmir Matson","doi":"10.1590/S0103-06631998000200004","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200004","url":null,"abstract":"Procedures aiming at removing stains form teeth have been widely pursued. Among these procedures are the techniques of enamel microbrasion, which can produce more favorable esthetic results. The aim of this study was to compare the results obtained clinically with application of different microabrasion techniques on white spot lesions, and also to evaluate enamel roughness in treated and untreated specimens using scanning electron microscopy. Patients with white spot lesions without cavitation were selected. On the first patient a mechanically applied clinical procedure was performed, while on the second one the clinical procedure was performed manually, and impressions were taken at different steps of the procedure in order to obtain samples to be examined under the scanning electron microscope. From the obtained results, it could conclude that the microabrasion techniques carried out with phosphoric acid and pumice flour, either with rotatory instruments or applied manually with a wood wegde, presented clinically satisfactory results. Under the scanning electron microscope, restoring of the superficial smoothness of treated enamel could be observed.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"31 1","pages":"105-112"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200005
Régia Luzia Zanata, Regina Guenka Palma, M. Navarro
The purpose of this study was to compare the microleakage of class V restorations using different combinations of glass ionomer/composite resin. Fifty cavities were prepared on the buccal and lingual aspects of recently extracted premolars and canines. The gingival margins of the preparations were extended into the cementum, and the occlusal margins were kept at the enamel level. The teeth were then divided into five groups and restored as follows: resin-modified glass ionomer cement restorative materials (Fuji II LC and Vitremer); composite resin/adhesive system (Scotchbond Multipurpose/Silux Plus); sandwich technique using the same composite resin/adhesive system and a resin-modified glass ionomer cement liner material (Vitrebond and GC Lining LC). The teeth were stored in distilled water, finished and thermocycled prior to immersion in a 2% basic fuchsin solution. The depth of dye penetration was scored and the results analyzed using Kruskal-Wallis and Wilcoxon Tests. The results revealed no significant differences between any of the groups for both cervical and occlusal margins.
本研究的目的是比较不同玻璃离子/复合树脂组合的V类修复体的微渗漏。在最近拔除的前臼齿和犬齿的颊部和舌部准备了50个空腔。制剂的牙龈边缘延伸到牙骨质，咬合边缘保持在牙釉质水平。采用树脂改性玻璃离子水门体修复材料(Fuji II LC和Vitremer)修复牙体;复合树脂/粘合剂系统(Scotchbond Multipurpose/Silux Plus);夹层技术使用相同的复合树脂/粘合剂系统和树脂改性玻璃离子水泥衬层材料(玻璃钢和GC衬层LC)。牙齿保存在蒸馏水中，在浸泡在2%的碱性品红溶液中之前，完成并进行热循环。对染料渗透深度进行评分，并使用Kruskal-Wallis和Wilcoxon试验对结果进行分析。结果显示，任何组之间的宫颈和咬合边缘均无显著差异。
{"title":"Avaliação in vitro da microinfiltração em cavidades de classe V restauradas com diferentes combinações de resina composta e cimento de ionômero de vidro","authors":"Régia Luzia Zanata, Regina Guenka Palma, M. Navarro","doi":"10.1590/S0103-06631998000200005","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200005","url":null,"abstract":"The purpose of this study was to compare the microleakage of class V restorations using different combinations of glass ionomer/composite resin. Fifty cavities were prepared on the buccal and lingual aspects of recently extracted premolars and canines. The gingival margins of the preparations were extended into the cementum, and the occlusal margins were kept at the enamel level. The teeth were then divided into five groups and restored as follows: resin-modified glass ionomer cement restorative materials (Fuji II LC and Vitremer); composite resin/adhesive system (Scotchbond Multipurpose/Silux Plus); sandwich technique using the same composite resin/adhesive system and a resin-modified glass ionomer cement liner material (Vitrebond and GC Lining LC). The teeth were stored in distilled water, finished and thermocycled prior to immersion in a 2% basic fuchsin solution. The depth of dye penetration was scored and the results analyzed using Kruskal-Wallis and Wilcoxon Tests. The results revealed no significant differences between any of the groups for both cervical and occlusal margins.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"113-119"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200014
Tomas Gomez, Matsuyoshi Mori, Gerson de Arruda Corrêa, Edmir Matson
The authors present a new metodology aiming to reduce the dimensional alterations of acrylic resins used for total prosthesis in order to eliminate the dimensional alterations, achiving better total prothesis and decreasing problems for patients.
{"title":"Alternativas técnicas para o controle das alterações dimensionais das resinas acrílicas em prótese total","authors":"Tomas Gomez, Matsuyoshi Mori, Gerson de Arruda Corrêa, Edmir Matson","doi":"10.1590/S0103-06631998000200014","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200014","url":null,"abstract":"The authors present a new metodology aiming to reduce the dimensional alterations of acrylic resins used for total prosthesis in order to eliminate the dimensional alterations, achiving better total prothesis and decreasing problems for patients.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"181-187"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200015
C. Gil, A. Nakamae
In this study a survey of 102 patients, 78 female and 24 male, aged between 18 and 61 years, was carried out in order to evaluate the severity of signs and symptoms of craniomandibular disorder (CMD). In each case, the degree of severity of the CMD was recorded following a score methodology according to clinical history, examination and study models. The following groups were observed: a) 34 patients wearing removable partial dentures (RPD) with unilateral absence of teeth (Kennedys Class II); b) 34 patients not wearing removable partial dentures with unilateral absence of teeth, and c) 34 patients with complete dental arches. All subjects in this survey presented some degree of pain or muscle discomfort. The results showed statistically significant differences between the three groups: the non RPD, partially edentulous subjects, with absence of teeth for more than 5 years had the worst degree of severity of signs and symptoms of CMD. It was concluded that the main signs and symptoms can be reliably evaluated utilizing this (CMI) score methodology.
本研究对102例患者进行了调查，其中女性78例，男性24例，年龄在18 ~ 61岁之间，目的是评估颅下颌骨疾病(CMD)体征和症状的严重程度。在每个病例中，根据临床病史、检查和研究模型，按照评分方法记录CMD的严重程度。观察组:a) 34例单侧缺牙的可摘局部义齿(RPD)患者(Kennedy’s Class II);B) 34例未佩戴可摘局部义齿单侧缺牙，c) 34例牙弓完整。本次调查的所有受试者都表现出不同程度的疼痛或肌肉不适。结果显示，三组间差异有统计学意义:非RPD组、部分无牙组、缺牙5年以上患者的CMD症状体征严重程度最差。结论是，使用CMI评分方法可以可靠地评估主要体征和症状。
{"title":"Distúrbios craniomandibulares em pacientes edentados unilaterais inferiores com e sem próteses parciais removíveis (PPR): um estudo transversal utilizando o índice craniomandibular (ICM)","authors":"C. Gil, A. Nakamae","doi":"10.1590/S0103-06631998000200015","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200015","url":null,"abstract":"In this study a survey of 102 patients, 78 female and 24 male, aged between 18 and 61 years, was carried out in order to evaluate the severity of signs and symptoms of craniomandibular disorder (CMD). In each case, the degree of severity of the CMD was recorded following a score methodology according to clinical history, examination and study models. The following groups were observed: a) 34 patients wearing removable partial dentures (RPD) with unilateral absence of teeth (Kennedys Class II); b) 34 patients not wearing removable partial dentures with unilateral absence of teeth, and c) 34 patients with complete dental arches. All subjects in this survey presented some degree of pain or muscle discomfort. The results showed statistically significant differences between the three groups: the non RPD, partially edentulous subjects, with absence of teeth for more than 5 years had the worst degree of severity of signs and symptoms of CMD. It was concluded that the main signs and symptoms can be reliably evaluated utilizing this (CMI) score methodology.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"189-197"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200012
Ilan Sampaio do Vale, A. S. Bramante, C. M. Bramante, O. Tavano
The aim of this article was to investigate the influence of the position of the imaging plate of the Digora digital system in the determination of tooth length. Sixty extracted human teeth were evaluated, divided into: ten maxillary incisors, ten mandibular incisors, ten maxillary bicuspids, ten mandibular bicuspids, ten maxillary molars, and ten mandibular molars. They were radiographed with the Digora imaging plate in two positions: long axis of the tooth parallel to the length of the plate, and long axis of the tooth parallel to the width of the same. The digital radiographic measurements of the specimens were obtained with the Digora system. The results showed no statistically significant differences between the digital radiographic measurements in either position, except for maxillary bicuspids and distal root of mandibular molars, although this difference was not clinically significant.
{"title":"Determinação do comprimento de dentes em função da posição da placa óptica do sistema de imagem digital Digora em relação ao eixo dentário","authors":"Ilan Sampaio do Vale, A. S. Bramante, C. M. Bramante, O. Tavano","doi":"10.1590/S0103-06631998000200012","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200012","url":null,"abstract":"The aim of this article was to investigate the influence of the position of the imaging plate of the Digora digital system in the determination of tooth length. Sixty extracted human teeth were evaluated, divided into: ten maxillary incisors, ten mandibular incisors, ten maxillary bicuspids, ten mandibular bicuspids, ten maxillary molars, and ten mandibular molars. They were radiographed with the Digora imaging plate in two positions: long axis of the tooth parallel to the length of the plate, and long axis of the tooth parallel to the width of the same. The digital radiographic measurements of the specimens were obtained with the Digora system. The results showed no statistically significant differences between the digital radiographic measurements in either position, except for maxillary bicuspids and distal root of mandibular molars, although this difference was not clinically significant.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"167-171"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67651235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1998-04-01DOI: 10.1590/S0103-06631998000200009
A. Garcia, E. Lara, H. Panzeri
Using the proper technology and cellulosic material (hydroxipropylmethylcellulose), it was possible to develop devices for the sustained release of the fluoride ion for application in the oral cavity. The drug used was sodium fluoride and the devices were prepared by compression or by coating of a nucleus, providing them with bioadhesiveness and adequate dimensions. As finished products, the devices fulfilled their objectives as they continuously delivered a small quantity of fluoride ions. As for fixation time, effective release was attained during 8 hours. In terms of therapeutic application, the device provides a series of advantages, the main one being the delivery of the therapeutic agent at the right site (on target) and its constant maintenance at this site in a small but effective concentration. The development of these devices opens up a whole new field of therapeutic systems.
{"title":"Estudo in vitro de sistemas bioadesivos para liberação sustentada de fluoreto","authors":"A. Garcia, E. Lara, H. Panzeri","doi":"10.1590/S0103-06631998000200009","DOIUrl":"https://doi.org/10.1590/S0103-06631998000200009","url":null,"abstract":"Using the proper technology and cellulosic material (hydroxipropylmethylcellulose), it was possible to develop devices for the sustained release of the fluoride ion for application in the oral cavity. The drug used was sodium fluoride and the devices were prepared by compression or by coating of a nucleus, providing them with bioadhesiveness and adequate dimensions. As finished products, the devices fulfilled their objectives as they continuously delivered a small quantity of fluoride ions. As for fixation time, effective release was attained during 8 hours. In terms of therapeutic application, the device provides a series of advantages, the main one being the delivery of the therapeutic agent at the right site (on target) and its constant maintenance at this site in a small but effective concentration. The development of these devices opens up a whole new field of therapeutic systems.","PeriodicalId":77611,"journal":{"name":"Revista de odontologia da Universidade de Sao Paulo","volume":"12 1","pages":"143-148"},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67650977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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