Pub Date : 2026-01-13DOI: 10.1213/ane.0000000000007925
Manuel C Pardo,Michael A Gropper
{"title":"Obituary: Dr Ronald D. Miller, 1939-2025-A Legacy of Excellence.","authors":"Manuel C Pardo,Michael A Gropper","doi":"10.1213/ane.0000000000007925","DOIUrl":"https://doi.org/10.1213/ane.0000000000007925","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1213/ane.0000000000007936
Anna Maria Biava,Gianni Cipriani,Endrit Malja,Federico Bilotta
{"title":"Opioid Use for Cesarean Delivery May Play a Role in Increased Risk of Postpartum Depression?","authors":"Anna Maria Biava,Gianni Cipriani,Endrit Malja,Federico Bilotta","doi":"10.1213/ane.0000000000007936","DOIUrl":"https://doi.org/10.1213/ane.0000000000007936","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1213/ane.0000000000007912
{"title":"Supply vs. Demand: The State of Pediatric Cardiac Anesthesiology.","authors":"","doi":"10.1213/ane.0000000000007912","DOIUrl":"https://doi.org/10.1213/ane.0000000000007912","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"3 1","pages":"231"},"PeriodicalIF":0.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145937876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDFrailty, characterized by reduced physiological resilience, is a pivotal risk factor in older adults undergoing major cardiac procedures. Although previous analyses have linked frailty to adverse surgical outcomes, knowledge gaps persist due to methodological inconsistency across frailty tools and limited synthesis of complications such as delirium, infection, and renal dysfunction. The objective of this systematic review and meta-analysis is to determine the prevalence of preoperative frailty in older adults undergoing major cardiac procedures, and assess its association with postoperative outcomes, including cardiac, respiratory, renal, infectious, stroke, and bleeding complications, postoperative delirium, hospital and intensive care unit (ICU) length of stay, nonhome discharge, hospital readmission, and both 30-day and 1-year mortality.METHODSA prespecified protocol was registered with PROSPERO (CRD#42024574916), following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, Embase, and Cochrane databases were searched for English-language studies of patients undergoing major cardiac procedures, including coronary artery bypass grafting (CABG), aortic or mitral valve replacement or repair, transcatheter aortic valve replacement (TAVR), or combined procedures. Validated frailty instruments (eg, Fried Frailty Phenotype, Clinical Frailty Scale) were required to determine preoperative frailty, along with reporting at least 1 postoperative outcome. Noncardiac surgeries, minor procedures, case reports, and reviews were excluded. Random-effects meta-analyses generated odds ratio (OR) or standardized mean difference (SMD) values with 95% confidence intervals (CI).RESULTSNineteen studies (n = 11,667; mean ± SD age 71.9 ± 8.1 years, 28% female) met inclusion criteria, spanning North America, Europe, Asia, and Oceania. The overall prevalence of preoperative frailty was 16.8%. Frailty was significantly associated with delirium (OR, 4.11; 95% confidence interval [CI], 2.00-8.45; P <.001), infection (OR, 3.72; 95% CI, 2.27-6.12; P <.001), renal complications (OR, 2.72; 95% CI, 2.05-3.60; P <.001), and extended hospital (SMD, 0.69 ; 95% CI, 0.35-1.02; P <.001) and ICU (SMD, 0.72; 95% CI, 0.51-0.94; P <.001) stays. Frailty increased the odds of 30-day (OR, 3.58; 95% CI, 2.16-5.93; P <.001) and 1-year (OR, 2.25; 95% CI, 1.56-3.25; P <.001) mortality.CONCLUSIONSFrailty affects nearly 1 in 5 older adults requiring major cardiac procedures. Frailty was significantly associated with adverse postoperative outcomes, including delirium, infections, renal complications, extended length of stay, and mortality. As frailty is potentially modifiable, targeted strategies-such as prehabilitation, nutritional optimization, and enhanced perioperative monitoring-may improve outcomes. Incorporating routine frailty screening into standard preoperative practice allows for earlier identification of high-risk patients, efficien
背景：身体虚弱，以生理恢复能力降低为特征，是接受重大心脏手术的老年人的关键危险因素。尽管先前的分析将虚弱与不良手术结果联系起来，但由于虚弱工具的方法不一致以及谵妄、感染和肾功能障碍等并发症的有限合成，知识差距仍然存在。本系统综述和荟萃分析的目的是确定接受重大心脏手术的老年人术前虚弱的患病率，并评估其与术后结局的关系，包括心脏、呼吸、肾脏、感染、中风和出血并发症、术后谵妄、住院和重症监护病房（ICU）住院时间、非家庭出院、再入院以及30天和1年死亡率。方法按照系统评价和荟萃分析（PRISMA）指南的首选报告项目，在PROSPERO （crd# 42024574916）上注册预先指定的方案。MEDLINE、Embase和Cochrane数据库检索了接受主要心脏手术的患者的英语研究，包括冠状动脉旁路移植术（CABG）、主动脉瓣或二尖瓣置换术或修复、经导管主动脉瓣置换术（TAVR）或联合手术。需要经过验证的衰弱仪器（例如，Fried衰弱表型，临床衰弱量表）来确定术前衰弱，并报告至少一项术后结果。排除了非心脏手术、小手术、病例报告和综述。随机效应荟萃分析产生95%置信区间（CI）的优势比（OR）或标准化平均差（SMD）值。结果19项研究（n = 11,667，平均±SD年龄71.9±8.1岁，女性28%）符合纳入标准，涵盖北美、欧洲、亚洲和大洋洲。术前虚弱的总体患病率为16.8%。虚弱与谵妄（OR, 4.11, 95%可信区间[CI]， 2.00-8.45, P < 0.001）、感染（OR, 3.72, 95% CI, 2.27-6.12, P < 0.001）、肾脏并发症（OR, 2.72, 95% CI, 2.05-3.60, P < 0.001）、延长住院时间（SMD, 0.69, 95% CI, 0.35-1.02, P < 0.001）和ICU （SMD, 0.72, 95% CI, 0.51-0.94, P < 0.001）相关。虚弱增加了30天死亡率（OR, 3.58; 95% CI, 2.16-5.93; P <.001）和1年死亡率（OR, 2.25; 95% CI, 1.56-3.25; P <.001）。结论：近五分之一需要进行大型心脏手术的老年人存在虚弱。虚弱与术后不良结果显著相关，包括谵妄、感染、肾脏并发症、延长住院时间和死亡率。由于虚弱是可以改变的，有针对性的策略，如康复、营养优化和加强围手术期监测，可能会改善结果。将常规虚弱筛查纳入标准术前实践，可以更早地识别高危患者，有效地分配资源，并制定围手术期护理计划。
{"title":"Association of Preoperative Frailty and Postoperative Outcomes in Older Adults Undergoing Major Cardiac Procedures: A Systematic Review and Meta-Analysis.","authors":"Vetri Thangavelu,Ojas Bhatia,Anushka Hasija,Nethmi Rajapakse,Ellene Yan,Aparna Saripella,Marina Englesakis,Frances Chung","doi":"10.1213/ane.0000000000007887","DOIUrl":"https://doi.org/10.1213/ane.0000000000007887","url":null,"abstract":"BACKGROUNDFrailty, characterized by reduced physiological resilience, is a pivotal risk factor in older adults undergoing major cardiac procedures. Although previous analyses have linked frailty to adverse surgical outcomes, knowledge gaps persist due to methodological inconsistency across frailty tools and limited synthesis of complications such as delirium, infection, and renal dysfunction. The objective of this systematic review and meta-analysis is to determine the prevalence of preoperative frailty in older adults undergoing major cardiac procedures, and assess its association with postoperative outcomes, including cardiac, respiratory, renal, infectious, stroke, and bleeding complications, postoperative delirium, hospital and intensive care unit (ICU) length of stay, nonhome discharge, hospital readmission, and both 30-day and 1-year mortality.METHODSA prespecified protocol was registered with PROSPERO (CRD#42024574916), following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, Embase, and Cochrane databases were searched for English-language studies of patients undergoing major cardiac procedures, including coronary artery bypass grafting (CABG), aortic or mitral valve replacement or repair, transcatheter aortic valve replacement (TAVR), or combined procedures. Validated frailty instruments (eg, Fried Frailty Phenotype, Clinical Frailty Scale) were required to determine preoperative frailty, along with reporting at least 1 postoperative outcome. Noncardiac surgeries, minor procedures, case reports, and reviews were excluded. Random-effects meta-analyses generated odds ratio (OR) or standardized mean difference (SMD) values with 95% confidence intervals (CI).RESULTSNineteen studies (n = 11,667; mean ± SD age 71.9 ± 8.1 years, 28% female) met inclusion criteria, spanning North America, Europe, Asia, and Oceania. The overall prevalence of preoperative frailty was 16.8%. Frailty was significantly associated with delirium (OR, 4.11; 95% confidence interval [CI], 2.00-8.45; P <.001), infection (OR, 3.72; 95% CI, 2.27-6.12; P <.001), renal complications (OR, 2.72; 95% CI, 2.05-3.60; P <.001), and extended hospital (SMD, 0.69 ; 95% CI, 0.35-1.02; P <.001) and ICU (SMD, 0.72; 95% CI, 0.51-0.94; P <.001) stays. Frailty increased the odds of 30-day (OR, 3.58; 95% CI, 2.16-5.93; P <.001) and 1-year (OR, 2.25; 95% CI, 1.56-3.25; P <.001) mortality.CONCLUSIONSFrailty affects nearly 1 in 5 older adults requiring major cardiac procedures. Frailty was significantly associated with adverse postoperative outcomes, including delirium, infections, renal complications, extended length of stay, and mortality. As frailty is potentially modifiable, targeted strategies-such as prehabilitation, nutritional optimization, and enhanced perioperative monitoring-may improve outcomes. Incorporating routine frailty screening into standard preoperative practice allows for earlier identification of high-risk patients, efficien","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145823988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDThe relationship between the bispectral index (BIS) and the BIS monitor's burst suppression ratio (BSR) has been extensively researched, with the current consensus being that BIS is fully driven by the BSR for BSR ≥ 40%. For lower BSR, the BIS seems to be derived from an unknown combination of electroencephalogram (EEG) parameters. In general, the BIS and BSR are not linearly correlated. With limited knowledge about the indices and their interactions, BIS- and BSR-driven anesthesia navigation may lead to index combinations showing paradoxical information.METHODSUsing intraoperative recordings of BIS and BSR from 62 patients 80.9 ± 5.8 (mean ± standard deviation [SD]) years, we analyzed the distribution of BIS and BSR values as well as their relation to each other with a focus on paradoxical situations, ie, an adequate BIS of 40 to 60 together with BSR ≥ 5%. We quantified the incidence rate and duration of these situations as well as the distribution of these BSR events within the BIS = 40 to 60 range.RESULTSOnly 56.9 [44-74.2]% (median [Q1-Q3]) BIS values fell inside the 40 to 60 range despite titration to this range. We found a disproportionately high incidence of BIS 41 to 42. BSR showed an exponentially declining, continuous distribution. We could observe paradoxical BIS and BSR values lasting for considerable stretches of time that could exceed 2 minutes.CONCLUSIONSBIS values are not continuously scaled, with some index values occurring distinctly more often. Paradoxical values of BIS between 40 and 60 and BSR≥5% can occur, potentially confusing anesthesia care providers.
{"title":"Paradoxical Combinations of Bispectral Index and Burst Suppression Ratio.","authors":"Duygu Aydin,Max Ebensperger,Stefan Schwerin,Bernhard Graf,Gerhard Schneider,Matthias Kreuzer,Barbara Sinner","doi":"10.1213/ane.0000000000007877","DOIUrl":"https://doi.org/10.1213/ane.0000000000007877","url":null,"abstract":"BACKGROUNDThe relationship between the bispectral index (BIS) and the BIS monitor's burst suppression ratio (BSR) has been extensively researched, with the current consensus being that BIS is fully driven by the BSR for BSR ≥ 40%. For lower BSR, the BIS seems to be derived from an unknown combination of electroencephalogram (EEG) parameters. In general, the BIS and BSR are not linearly correlated. With limited knowledge about the indices and their interactions, BIS- and BSR-driven anesthesia navigation may lead to index combinations showing paradoxical information.METHODSUsing intraoperative recordings of BIS and BSR from 62 patients 80.9 ± 5.8 (mean ± standard deviation [SD]) years, we analyzed the distribution of BIS and BSR values as well as their relation to each other with a focus on paradoxical situations, ie, an adequate BIS of 40 to 60 together with BSR ≥ 5%. We quantified the incidence rate and duration of these situations as well as the distribution of these BSR events within the BIS = 40 to 60 range.RESULTSOnly 56.9 [44-74.2]% (median [Q1-Q3]) BIS values fell inside the 40 to 60 range despite titration to this range. We found a disproportionately high incidence of BIS 41 to 42. BSR showed an exponentially declining, continuous distribution. We could observe paradoxical BIS and BSR values lasting for considerable stretches of time that could exceed 2 minutes.CONCLUSIONSBIS values are not continuously scaled, with some index values occurring distinctly more often. Paradoxical values of BIS between 40 and 60 and BSR≥5% can occur, potentially confusing anesthesia care providers.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145823889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-23DOI: 10.1213/ane.0000000000007890
Ryan O Parker,Joshua W Sappenfield
{"title":"Posttraumatic Stress Disorder: A Milligram of Prevention for a Life-Long Problem?","authors":"Ryan O Parker,Joshua W Sappenfield","doi":"10.1213/ane.0000000000007890","DOIUrl":"https://doi.org/10.1213/ane.0000000000007890","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145823891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-22DOI: 10.1213/ane.0000000000007884
Jacob Provencio,Connor J Evans,Jennifer A Achay,R Lyle Hood,Robert A De Lorenzo,Steven Venticinque
{"title":"A Novel, Human Cadaveric Airway Model for Preclinical Testing of Medical Devices and Interventions: The Dynamic Airway Patency Model.","authors":"Jacob Provencio,Connor J Evans,Jennifer A Achay,R Lyle Hood,Robert A De Lorenzo,Steven Venticinque","doi":"10.1213/ane.0000000000007884","DOIUrl":"https://doi.org/10.1213/ane.0000000000007884","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145801338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-16DOI: 10.1213/ane.0000000000007856
Ian A Jones,Kevin C Liu,Matthew A Lim,Sagar Telang,Julian Wier,Nathanael D Heckmann
BACKGROUNDRetrospective studies suggest that dexamethasone may provide benefits that extend beyond its antiemetic properties, including a reduction in postoperative complications. However, results from randomized controlled trials have not consistently shown there to be a reduction in composite major adverse events. This discrepancy may be due to confounding factors, measurement error, or simultaneity bias among retrospective investigations. This study used instrumental variable analysis (IVA) to help address potential sources of bias and better estimate treatment effects in patients undergoing total joint arthroplasty (TJA).METHODSPatients who underwent primary elective TJA between 2016 and 2021 were identified using diagnosis and procedural codes. Bivariate regression, multivariable regression, and IVA were conducted. The primary end point was a 90-day composite (any versus none) of major postoperative medical complications. Secondary outcomes were infection, readmission, and death. Two distinct instruments-the frequency of dexamethasone use by surgeon and by hospital-were used to evaluate the robustness of our IVA. Patient demographics, hospital factors, and comorbidities were reported using descriptive statistics. Instrumental variable covariates were selected using the least absolute shrinkage and selection operator with 3 regularization parameter strategies.RESULTS1525,844 TJAs performed between 2015 and 2021 were identified (976,996 knees [total knee arthroplasty {TKA}]; 548,848 hips [total hip arthroplasty {THA}]). Major postoperative medical complications were observed in 31,299 (3.43%) dexamethasone-exposed patients compared to 31,266 (4.87%) unexposed patients. Surgeon-based IVA yielded results comparable to the multivariable and bivariate analysis (local average treatment effect [LATE]: TKA: -1.20% [95% confidence interval [CI], -1.33% to -1.08%]; THA: -1.14% [95% CI, -1.30% to -0.99%]). Hospital-based IVA produced similar findings (LATE: TKA: -1.23% [95% CI, -1.38% to -1.09%]; THA: -1.18% [95% CI, -1.35% to -1.00%]). Both instruments demonstrated high F-statistics and significant Hausman tests. Secondary outcomes mirrored these results, except for mortality, which did not meet endogeneity criteria across analyses.CONCLUSIONSThe findings of this study support that dexamethasone exposure is associated with a reduction in composite major postoperative complications after TJA. The observed moderate treatment effect, in conjunction with a low baseline incidence of adverse events, may explain the inconsistent outcomes reported in previous randomized trials. Future prospective studies should incorporate composite end points and target high-risk patient populations or procedural subgroups.
{"title":"Association of Perioperative Dexamethasone With Postoperative Complications After Primary Total Joint Arthroplasty: An Instrumental Variable Analysis.","authors":"Ian A Jones,Kevin C Liu,Matthew A Lim,Sagar Telang,Julian Wier,Nathanael D Heckmann","doi":"10.1213/ane.0000000000007856","DOIUrl":"https://doi.org/10.1213/ane.0000000000007856","url":null,"abstract":"BACKGROUNDRetrospective studies suggest that dexamethasone may provide benefits that extend beyond its antiemetic properties, including a reduction in postoperative complications. However, results from randomized controlled trials have not consistently shown there to be a reduction in composite major adverse events. This discrepancy may be due to confounding factors, measurement error, or simultaneity bias among retrospective investigations. This study used instrumental variable analysis (IVA) to help address potential sources of bias and better estimate treatment effects in patients undergoing total joint arthroplasty (TJA).METHODSPatients who underwent primary elective TJA between 2016 and 2021 were identified using diagnosis and procedural codes. Bivariate regression, multivariable regression, and IVA were conducted. The primary end point was a 90-day composite (any versus none) of major postoperative medical complications. Secondary outcomes were infection, readmission, and death. Two distinct instruments-the frequency of dexamethasone use by surgeon and by hospital-were used to evaluate the robustness of our IVA. Patient demographics, hospital factors, and comorbidities were reported using descriptive statistics. Instrumental variable covariates were selected using the least absolute shrinkage and selection operator with 3 regularization parameter strategies.RESULTS1525,844 TJAs performed between 2015 and 2021 were identified (976,996 knees [total knee arthroplasty {TKA}]; 548,848 hips [total hip arthroplasty {THA}]). Major postoperative medical complications were observed in 31,299 (3.43%) dexamethasone-exposed patients compared to 31,266 (4.87%) unexposed patients. Surgeon-based IVA yielded results comparable to the multivariable and bivariate analysis (local average treatment effect [LATE]: TKA: -1.20% [95% confidence interval [CI], -1.33% to -1.08%]; THA: -1.14% [95% CI, -1.30% to -0.99%]). Hospital-based IVA produced similar findings (LATE: TKA: -1.23% [95% CI, -1.38% to -1.09%]; THA: -1.18% [95% CI, -1.35% to -1.00%]). Both instruments demonstrated high F-statistics and significant Hausman tests. Secondary outcomes mirrored these results, except for mortality, which did not meet endogeneity criteria across analyses.CONCLUSIONSThe findings of this study support that dexamethasone exposure is associated with a reduction in composite major postoperative complications after TJA. The observed moderate treatment effect, in conjunction with a low baseline incidence of adverse events, may explain the inconsistent outcomes reported in previous randomized trials. Future prospective studies should incorporate composite end points and target high-risk patient populations or procedural subgroups.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"370 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145765395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-16DOI: 10.1213/ane.0000000000007889
Nicholas J L Brown,John B Carlisle
{"title":"Detecting Inconsistencies and Fraud in Research Data: Time for Authors to Share the Data Underlying Their Summary Statistics as a Matter of Course.","authors":"Nicholas J L Brown,John B Carlisle","doi":"10.1213/ane.0000000000007889","DOIUrl":"https://doi.org/10.1213/ane.0000000000007889","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145765476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：