Pub Date : 2026-01-29DOI: 10.1213/ane.0000000000007956
Elizabeth A Wilson,Evan D Kharasch
{"title":"Opioids Reconsidered: From Antinociception to Potential Organ Protection.","authors":"Elizabeth A Wilson,Evan D Kharasch","doi":"10.1213/ane.0000000000007956","DOIUrl":"https://doi.org/10.1213/ane.0000000000007956","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-29DOI: 10.1213/ane.0000000000007883
Jose Rios-Monterrosa,Samuel Castro,Chance Aguiar,Ali Tanvir,Amanda Woodward,Louise Y Sun,Adam J Milam
Health care disparities, particularly among minoritized groups, pose significant challenges within health care systems, including the field of cardiac surgery. Limited English proficiency (LEP) is an often-overlooked factor contributing to these disparities. As key members of the preoperative evaluation, intraoperative management, and postoperative care of cardiac surgery patients, anesthesiologists have both ethical and economic responsibilities to understand, recognize, and address disparities to ensure equitable care for all patients. The objective of this scoping review is to summarize the literature on how LEP impacts the utilization of health services and outcomes after cardiac surgery. More specifically, the review will map how LEP is defined in the literature, summarize the patient populations that have been studied, and describe the health care outcomes in patients with LEP after cardiac surgery. A comprehensive literature search strategy was developed in collaboration with a medical librarian and was registered before conducting the search. Studies were eligible for inclusion in our current study if (i) the patient population was composed of adults (>or = 18), (ii) the study reported health care outcomes before or after cardiac surgery, and (iii) results were stratified by a patient's English proficiency. All randomized control trials, systematic reviews, observational studies, and cross-sectional studies published in English were included in our study. If conference abstracts met the inclusion criteria, they were included for full-text review. Opinion articles and case reports were excluded. The search produced 2401 articles with 13 articles meeting the inclusion criteria. All studies were conducted in either North America or Australia/New Zealand. The number of patients included in each study ranged from 204 to 21,789, with 4 studies having less than 1500 patients and 2 studies having greater than 10,000 patients. Through a systematic review of the literature on this topic, we identified 3 overarching themes that were inferred from the collective body of studies. First, a significant barrier to studying this topic is the absence of a universal definition of LEP. Second, the heterogeneity in several aspects of the available studies makes it difficult to draw conclusions from the results. Finally, there is a general scarcity of research done on the impact of LEP on cardiac surgery outcomes. Ultimately, our scoping review reveals an area of health disparity research that requires more attention. If disparities are found, then health care leaders may begin investigating which interventions can help mitigate these disparities.
{"title":"Does Language Matter? The Impact of English Proficiency on Healthcare Outcomes After Cardiac Surgery: A Scoping Review.","authors":"Jose Rios-Monterrosa,Samuel Castro,Chance Aguiar,Ali Tanvir,Amanda Woodward,Louise Y Sun,Adam J Milam","doi":"10.1213/ane.0000000000007883","DOIUrl":"https://doi.org/10.1213/ane.0000000000007883","url":null,"abstract":"Health care disparities, particularly among minoritized groups, pose significant challenges within health care systems, including the field of cardiac surgery. Limited English proficiency (LEP) is an often-overlooked factor contributing to these disparities. As key members of the preoperative evaluation, intraoperative management, and postoperative care of cardiac surgery patients, anesthesiologists have both ethical and economic responsibilities to understand, recognize, and address disparities to ensure equitable care for all patients. The objective of this scoping review is to summarize the literature on how LEP impacts the utilization of health services and outcomes after cardiac surgery. More specifically, the review will map how LEP is defined in the literature, summarize the patient populations that have been studied, and describe the health care outcomes in patients with LEP after cardiac surgery. A comprehensive literature search strategy was developed in collaboration with a medical librarian and was registered before conducting the search. Studies were eligible for inclusion in our current study if (i) the patient population was composed of adults (>or = 18), (ii) the study reported health care outcomes before or after cardiac surgery, and (iii) results were stratified by a patient's English proficiency. All randomized control trials, systematic reviews, observational studies, and cross-sectional studies published in English were included in our study. If conference abstracts met the inclusion criteria, they were included for full-text review. Opinion articles and case reports were excluded. The search produced 2401 articles with 13 articles meeting the inclusion criteria. All studies were conducted in either North America or Australia/New Zealand. The number of patients included in each study ranged from 204 to 21,789, with 4 studies having less than 1500 patients and 2 studies having greater than 10,000 patients. Through a systematic review of the literature on this topic, we identified 3 overarching themes that were inferred from the collective body of studies. First, a significant barrier to studying this topic is the absence of a universal definition of LEP. Second, the heterogeneity in several aspects of the available studies makes it difficult to draw conclusions from the results. Finally, there is a general scarcity of research done on the impact of LEP on cardiac surgery outcomes. Ultimately, our scoping review reveals an area of health disparity research that requires more attention. If disparities are found, then health care leaders may begin investigating which interventions can help mitigate these disparities.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-26DOI: 10.1213/ane.0000000000007911
Nicholas V Mendez,Daniel Chan,Ty Thompson,David Chen,Sebastian Zeiner,Rishi P Kothari,Hillary J Braun,Michael P Bokoch,Kerstin Kolodzie,Dieter Adelmann
BACKGROUNDAcute kidney injury (AKI) is common after liver transplant and associated with increased morbidity and mortality. Transplantation of nonrenal organs is also associated with eventual chronic kidney disease (CKD). Development of CKD after liver transplant is known to be multifactorial; however, this study evaluates the unique contribution of AKI in this complex disease pathway.METHODSPatients were classified into 2 groups: presence or absence of severe AKI within 72 hours postoperatively. Kidney function was assessed at year 1: normal/mild (estimated glomerular filtration rate [eGFR] ≥60 mL/min/1.73 m2); moderate (30 ≤eGFR <60 mL/min/1.73 m2); or severe (eGFR <30 mL/min/1.73m2) disease. Adjusted relative risks of both CKD and death at years 1 through 3 in the presence versus absence of severe AKI were estimated using discrete-time targeted maximum likelihood estimation.RESULTSOf 1574 patients, 769 (49%) experienced severe AKI. At year 1, 1024 (65%) patients had normal/mild, 487 (31%) had moderate, and 63 (4%) had severe CKD. The unadjusted relative risk of severe CKD was 3.66 (95% confidence interval [CI], 2.15-7.33), and the adjusted relative risk was 2.62 (95% CI, 1.61-4.28) in patients with severe AKI. In total, 66 (4%), 115 (7%), and 147 (9%) patients died in years 1, 2, and 3, respectively. Patients with severe AKI had an unadjusted relative risk of death at year 1 of 2.41 (95% CI, 1.47-4.19) compared to an adjusted relative risk of 1.15 (95% CI, 1.04-1.28); at year 2, the unadjusted relative risk of death was 1.51 (95% CI, 1.07-2.19) compared to an adjusted relative risk of 1.14 (95% CI, 1.04-1.25); and at year 3, the unadjusted relative risk of death was 1.44 (95% CI, 1.05-1.97) compared to an adjusted relative risk of 1.13 (95% CI, 1.04-1.23).CONCLUSIONSevere postoperative AKI is associated with an increased risk of severe CKD at 1 year and mortality up to 3 years after liver transplant. Postoperative AKI represents an important target for future perioperative interventions aimed at mitigating the risk of long-term morbidity and mortality for liver transplant patients.
{"title":"Contribution of Acute Kidney Injury After Liver Transplant in Development of Chronic Kidney Disease: A Single-Center Retrospective Cohort Study.","authors":"Nicholas V Mendez,Daniel Chan,Ty Thompson,David Chen,Sebastian Zeiner,Rishi P Kothari,Hillary J Braun,Michael P Bokoch,Kerstin Kolodzie,Dieter Adelmann","doi":"10.1213/ane.0000000000007911","DOIUrl":"https://doi.org/10.1213/ane.0000000000007911","url":null,"abstract":"BACKGROUNDAcute kidney injury (AKI) is common after liver transplant and associated with increased morbidity and mortality. Transplantation of nonrenal organs is also associated with eventual chronic kidney disease (CKD). Development of CKD after liver transplant is known to be multifactorial; however, this study evaluates the unique contribution of AKI in this complex disease pathway.METHODSPatients were classified into 2 groups: presence or absence of severe AKI within 72 hours postoperatively. Kidney function was assessed at year 1: normal/mild (estimated glomerular filtration rate [eGFR] ≥60 mL/min/1.73 m2); moderate (30 ≤eGFR <60 mL/min/1.73 m2); or severe (eGFR <30 mL/min/1.73m2) disease. Adjusted relative risks of both CKD and death at years 1 through 3 in the presence versus absence of severe AKI were estimated using discrete-time targeted maximum likelihood estimation.RESULTSOf 1574 patients, 769 (49%) experienced severe AKI. At year 1, 1024 (65%) patients had normal/mild, 487 (31%) had moderate, and 63 (4%) had severe CKD. The unadjusted relative risk of severe CKD was 3.66 (95% confidence interval [CI], 2.15-7.33), and the adjusted relative risk was 2.62 (95% CI, 1.61-4.28) in patients with severe AKI. In total, 66 (4%), 115 (7%), and 147 (9%) patients died in years 1, 2, and 3, respectively. Patients with severe AKI had an unadjusted relative risk of death at year 1 of 2.41 (95% CI, 1.47-4.19) compared to an adjusted relative risk of 1.15 (95% CI, 1.04-1.28); at year 2, the unadjusted relative risk of death was 1.51 (95% CI, 1.07-2.19) compared to an adjusted relative risk of 1.14 (95% CI, 1.04-1.25); and at year 3, the unadjusted relative risk of death was 1.44 (95% CI, 1.05-1.97) compared to an adjusted relative risk of 1.13 (95% CI, 1.04-1.23).CONCLUSIONSevere postoperative AKI is associated with an increased risk of severe CKD at 1 year and mortality up to 3 years after liver transplant. Postoperative AKI represents an important target for future perioperative interventions aimed at mitigating the risk of long-term morbidity and mortality for liver transplant patients.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146056862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1213/ane.0000000000007940
Morgan L Brown,David Whiting,James A DiNardo,Viviane G Nasr
{"title":"Institutional Experience Introducing Portable Capnography Intrahospital Transport of Ventilated Patients With Congenital Heart Disease.","authors":"Morgan L Brown,David Whiting,James A DiNardo,Viviane G Nasr","doi":"10.1213/ane.0000000000007940","DOIUrl":"https://doi.org/10.1213/ane.0000000000007940","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1213/ane.0000000000007907
Muge Qile,Zhaofei Luo,Chao Wu,Xueying Cheng,Yu Zhang,Liu Liu,Qingtong Wang,Ye Zhang,Eric R Gross,Shufang He
BACKGROUNDMyocardial ischemia/reperfusion (I/R) injury commonly occurs in patients undergoing cardiac or noncardiac surgeries, increasing perioperative mortality risk. Although numerous endogenous mediators released during I/R contribute to myocardial damage, their mechanisms require further elucidation. We investigated whether lysophosphatidic acid (LPA), a bioactive phospholipid, mediates myocardial I/R injury by interacting with cardiac transient receptor potential vanilloid 1 (TRPV1).METHODSA TRPV1K710N knock-in mouse model was generated by CRISPR/Cas9, introducing a point mutation at K710, the known LPA-binding site on TRPV1. Langendorff perfused isolated hearts from TRPV1K710N and wild-type (WT) mice underwent global I/R injury with or without exogenous LPA (10 μM). Myocardial infarct size, coronary effluent LDH levels, and mitochondrial ultrastructure/function were assessed. Additionally, H9c2 cardiomyocytes were transfected with a pCMV6-entry plasmid carrying TRPV1-K710N or TRPV1-WT for mitochondrial calcium influx and cell viability assays. The V1-Cal peptide (1μM), targeting the K710 region, was applied ex vivo and in vitro to block LPA-TRPV1 interaction.RESULTSTRPV1K710N hearts exhibited resistance to global I/R injury versus WT hearts, with reduced infarct size (28.3 ± 2.4% vs 39.9 ±2.3%, respectively, P= 0006), lower LDH levels, and attenuated mitochondrial damage. Exogenous LPA exacerbated I/R injury in WT hearts, increasing infarct size (63.7 ± 1.2% vs vehicle: 38.4 ± 2.4%; P <.0001), LDH release, and mitochondrial damage. TRPV1K710N hearts were resistant to LPA-induced injury, with no significant increase in infarct size after LPA treatment. Exogenous LPA induced pronounced swelling in mitochondria isolated from WT hearts, while mitochondria from TRPV1K710N hearts showed resistance to LPA challenge. In H9c2 cells, LPA significantly decreased viability in rTRPV1-WT cells and elevated mitochondrial calcium influx relative to rTRPV1-K710N cells. V1-Cal peptide attenuated LPA-mediated myocardial injury in WT hearts and reduced mitochondrial calcium overload in H9c2 cells.CONCLUSIONSBlockade of the TRPV1 K710 site by K710N mutation or V1-Cal peptide mitigates LPA-mediated myocardial injury and mitochondrial damage/dysfunction in isolated mouse hearts. Targeting the cardiac LPA-TRPV1 interaction represents a promising therapeutic strategy against perioperative myocardial injury.
{"title":"Site-Specific Blockade of LPA-TRPV1 Interaction at K710 Residue Influences on Myocardial Ischemia/Reperfusion Injury in Ex Vivo Mouse Hearts.","authors":"Muge Qile,Zhaofei Luo,Chao Wu,Xueying Cheng,Yu Zhang,Liu Liu,Qingtong Wang,Ye Zhang,Eric R Gross,Shufang He","doi":"10.1213/ane.0000000000007907","DOIUrl":"https://doi.org/10.1213/ane.0000000000007907","url":null,"abstract":"BACKGROUNDMyocardial ischemia/reperfusion (I/R) injury commonly occurs in patients undergoing cardiac or noncardiac surgeries, increasing perioperative mortality risk. Although numerous endogenous mediators released during I/R contribute to myocardial damage, their mechanisms require further elucidation. We investigated whether lysophosphatidic acid (LPA), a bioactive phospholipid, mediates myocardial I/R injury by interacting with cardiac transient receptor potential vanilloid 1 (TRPV1).METHODSA TRPV1K710N knock-in mouse model was generated by CRISPR/Cas9, introducing a point mutation at K710, the known LPA-binding site on TRPV1. Langendorff perfused isolated hearts from TRPV1K710N and wild-type (WT) mice underwent global I/R injury with or without exogenous LPA (10 μM). Myocardial infarct size, coronary effluent LDH levels, and mitochondrial ultrastructure/function were assessed. Additionally, H9c2 cardiomyocytes were transfected with a pCMV6-entry plasmid carrying TRPV1-K710N or TRPV1-WT for mitochondrial calcium influx and cell viability assays. The V1-Cal peptide (1μM), targeting the K710 region, was applied ex vivo and in vitro to block LPA-TRPV1 interaction.RESULTSTRPV1K710N hearts exhibited resistance to global I/R injury versus WT hearts, with reduced infarct size (28.3 ± 2.4% vs 39.9 ±2.3%, respectively, P= 0006), lower LDH levels, and attenuated mitochondrial damage. Exogenous LPA exacerbated I/R injury in WT hearts, increasing infarct size (63.7 ± 1.2% vs vehicle: 38.4 ± 2.4%; P <.0001), LDH release, and mitochondrial damage. TRPV1K710N hearts were resistant to LPA-induced injury, with no significant increase in infarct size after LPA treatment. Exogenous LPA induced pronounced swelling in mitochondria isolated from WT hearts, while mitochondria from TRPV1K710N hearts showed resistance to LPA challenge. In H9c2 cells, LPA significantly decreased viability in rTRPV1-WT cells and elevated mitochondrial calcium influx relative to rTRPV1-K710N cells. V1-Cal peptide attenuated LPA-mediated myocardial injury in WT hearts and reduced mitochondrial calcium overload in H9c2 cells.CONCLUSIONSBlockade of the TRPV1 K710 site by K710N mutation or V1-Cal peptide mitigates LPA-mediated myocardial injury and mitochondrial damage/dysfunction in isolated mouse hearts. Targeting the cardiac LPA-TRPV1 interaction represents a promising therapeutic strategy against perioperative myocardial injury.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1213/ane.0000000000007902
Yangzi Zhu,Ying Wu,Kailun Gao,Yuning Sun,Junfeng Hu,Liwei Wang,Jun-Li Cao
BACKGROUNDThe surgical interventions aimed at fracture repair are often accompanied by chronic postsurgical pain (CPSP), which is associated with depression, impaired quality of life, and increased societal burden. This phenomenon is particularly understudied in young patients with distal lower extremity fracture. Developing a scalable and accurate predictive model could improve postoperative care by enabling early detection of high-risk patients and guiding personalized pain management strategies.METHODSThis study collected in-hospital medical records and conducted follow-up for all patients over a 1-year period. We developed a predictive model through a 3-stage approach involving Least Absolute Shrinkage and Selection Operator (LASSO) regression, information gain analysis, and multivariable logistic regression, followed by model validation. Using the Shinyapps.io platform to build a webpage risk calculator for the final prediction model.RESULTSThe final cohort included 818 patients: 38.4% of whom experienced CPSP, and 18.2% of patients with CPSP developed neuropathic pain. There are 6 independent variables associated with CPSP: postoperative analgesic technique, fixation type, preoperative clinical management, and numerical rating scale (NRS) score on the day of the visit and postoperative day 1. The optimism-corrected area under the receiver operating curve for the development cohort and validation cohort were 0.872 and 0.838, respectively, and this model demonstrated good calibration and clinical utility. A web-based predictive nomogram was established by integrating machine learning-based big data variable screening with the interpretability of traditional logistic regression.CONCLUSIONSThis study demonstrates that pain management strategies, surgical approaches, and patient psychological factors collectively influence the development of CPSP. By integrating machine learning-based big data variable screening with the interpretability of traditional logistic regression, we developed a web-based predictive nomogram capable of identifying early CPSP risk at hospital discharge, thereby improving accessibility to transitional pain care interventions.
{"title":"Risk Factors and Prediction of Chronic Postsurgical Pain Among Patients With Distal Lower Extremity Fracture: Cohort Analysis.","authors":"Yangzi Zhu,Ying Wu,Kailun Gao,Yuning Sun,Junfeng Hu,Liwei Wang,Jun-Li Cao","doi":"10.1213/ane.0000000000007902","DOIUrl":"https://doi.org/10.1213/ane.0000000000007902","url":null,"abstract":"BACKGROUNDThe surgical interventions aimed at fracture repair are often accompanied by chronic postsurgical pain (CPSP), which is associated with depression, impaired quality of life, and increased societal burden. This phenomenon is particularly understudied in young patients with distal lower extremity fracture. Developing a scalable and accurate predictive model could improve postoperative care by enabling early detection of high-risk patients and guiding personalized pain management strategies.METHODSThis study collected in-hospital medical records and conducted follow-up for all patients over a 1-year period. We developed a predictive model through a 3-stage approach involving Least Absolute Shrinkage and Selection Operator (LASSO) regression, information gain analysis, and multivariable logistic regression, followed by model validation. Using the Shinyapps.io platform to build a webpage risk calculator for the final prediction model.RESULTSThe final cohort included 818 patients: 38.4% of whom experienced CPSP, and 18.2% of patients with CPSP developed neuropathic pain. There are 6 independent variables associated with CPSP: postoperative analgesic technique, fixation type, preoperative clinical management, and numerical rating scale (NRS) score on the day of the visit and postoperative day 1. The optimism-corrected area under the receiver operating curve for the development cohort and validation cohort were 0.872 and 0.838, respectively, and this model demonstrated good calibration and clinical utility. A web-based predictive nomogram was established by integrating machine learning-based big data variable screening with the interpretability of traditional logistic regression.CONCLUSIONSThis study demonstrates that pain management strategies, surgical approaches, and patient psychological factors collectively influence the development of CPSP. By integrating machine learning-based big data variable screening with the interpretability of traditional logistic regression, we developed a web-based predictive nomogram capable of identifying early CPSP risk at hospital discharge, thereby improving accessibility to transitional pain care interventions.","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1213/ane.0000000000007896
Chen-Hwan Cherng
{"title":"LEMONS: Incorporating Stiffness of Submental/Submandibular Space into Difficult Airway Assessment.","authors":"Chen-Hwan Cherng","doi":"10.1213/ane.0000000000007896","DOIUrl":"https://doi.org/10.1213/ane.0000000000007896","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1213/ane.0000000000007903
Craig S Jabaley,Mark E Nunnally,Brigid C Flynn
{"title":"Medical Society Guideline Writing: The Why and How.","authors":"Craig S Jabaley,Mark E Nunnally,Brigid C Flynn","doi":"10.1213/ane.0000000000007903","DOIUrl":"https://doi.org/10.1213/ane.0000000000007903","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"390 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1213/ane.0000000000007935
Alexander Nagrebetsky,Girish P Joshi
{"title":"Prolonged Fasting and Patient-Centered Outcomes: When Science Meets Common Sense.","authors":"Alexander Nagrebetsky,Girish P Joshi","doi":"10.1213/ane.0000000000007935","DOIUrl":"https://doi.org/10.1213/ane.0000000000007935","url":null,"abstract":"","PeriodicalId":7799,"journal":{"name":"Anesthesia & Analgesia","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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