Pub Date : 1969-01-01DOI: 10.1177/030098586900600304
D F Kelly
Diffuse proliferative and necrotizing trachcobronchitis, intranuclear inclusions, and pulmonary hyaline membranes were found in a 1-year-old female dachshund which was killed because of severe respiratory disease. Histologically the lesions resemble those described in adenoviral infections in calves, pigs, and man but a specific cause was not determined.
{"title":"Canine proliferative and necrotizing tracheobronchitis, with intranuclear inclusion-body and hyaline membrane formation.","authors":"D F Kelly","doi":"10.1177/030098586900600304","DOIUrl":"https://doi.org/10.1177/030098586900600304","url":null,"abstract":"Diffuse proliferative and necrotizing trachcobronchitis, intranuclear inclusions, and pulmonary hyaline membranes were found in a 1-year-old female dachshund which was killed because of severe respiratory disease. Histologically the lesions resemble those described in adenoviral infections in calves, pigs, and man but a specific cause was not determined.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 3","pages":"227-34"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15294936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600401
G R Johnson, A Koestner, O Kindig, J A Shadduck
The effects of a pathogenic canine herpesvirus were studied sequentially in established canine thyroid adenocarcinoma tissue culture cells. The lesions were defined as early, middle, and late manifestations of viral effects based on the time a lesion first appeared. The early phase (3 to 10 hours) consisted of nucleolar swelling followed by disruption. The nucleolar changes were characterized by loss of RNA as determined with acridine orange and segregation of the nucleolar components as demonstrated by electron microscopy. The middle phase (10 to 34 hours) was characterized by the appearance of three types of eosinophilic intranuclear inclusions. One type of inclusion appeared to transform progressively into another. The appearance of viral antigen in the nucleus as demonstrated by immunofluorescence, correlated with ultrastructural evidence of viral replication. The late phase (34 to 72 hours) was manifested by cellular degeneration and viral release into the cytoplasm.
{"title":"Effects of a pathogenic canine herpesvirus on established thyroid adenocarcinoma cell cultures.","authors":"G R Johnson, A Koestner, O Kindig, J A Shadduck","doi":"10.1177/030098586900600401","DOIUrl":"https://doi.org/10.1177/030098586900600401","url":null,"abstract":"The effects of a pathogenic canine herpesvirus were studied sequentially in established canine thyroid adenocarcinoma tissue culture cells. The lesions were defined as early, middle, and late manifestations of viral effects based on the time a lesion first appeared. The early phase (3 to 10 hours) consisted of nucleolar swelling followed by disruption. The nucleolar changes were characterized by loss of RNA as determined with acridine orange and segregation of the nucleolar components as demonstrated by electron microscopy. The middle phase (10 to 34 hours) was characterized by the appearance of three types of eosinophilic intranuclear inclusions. One type of inclusion appeared to transform progressively into another. The appearance of viral antigen in the nucleus as demonstrated by immunofluorescence, correlated with ultrastructural evidence of viral replication. The late phase (34 to 72 hours) was manifested by cellular degeneration and viral release into the cytoplasm.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"289-308"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15294265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600405
F Wright, A C Palmer
The morphological changes in the spinal cord caused by pressure are described in a series of domestic animals of various species. Three types of lesion are distinguished: totally malacic, partially malacic, and non-malacic. In the non-malacic lesion changes are predominantly in the white matter and consist of de-myclination and hyalinisation of small vessels. The possibility that the immediate cause of such non-malacic lesions may be obstruction of venous drainage from the spinal cord is discussed.
{"title":"Morphological changes caused by pressure on the spinal cord.","authors":"F Wright, A C Palmer","doi":"10.1177/030098586900600405","DOIUrl":"https://doi.org/10.1177/030098586900600405","url":null,"abstract":"The morphological changes in the spinal cord caused by pressure are described in a series of domestic animals of various species. Three types of lesion are distinguished: totally malacic, partially malacic, and non-malacic. In the non-malacic lesion changes are predominantly in the white matter and consist of de-myclination and hyalinisation of small vessels. The possibility that the immediate cause of such non-malacic lesions may be obstruction of venous drainage from the spinal cord is discussed.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"355-68"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600405","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15294267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900601s01
R G Thomson
{"title":"Vertebral body osteophytes in bulls.","authors":"R G Thomson","doi":"10.1177/030098586900601s01","DOIUrl":"https://doi.org/10.1177/030098586900601s01","url":null,"abstract":"","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":" ","pages":"Suppl 6:1-46"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900601s01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15299062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600202
K C Hayes, B Schiefer
Nineteen primary tumors of the central nervous system from dogs and 4 from cats are described. In the group of dogs, 15 were from brachycephalic breeds and 10 of these were boxers. Their tumors included 3 glioblastomas, 3 oligodendrogliomas, 3 astrocytomas, 3 ependymomas, 2 medulloblastomas, 4 meningiomas, and 1 malignant meningioma. One ependymoma and 1 meningioma were located in the spinal cord. The 4 neoplasms from cats were meningiomas.
{"title":"Primary tumors in the CNS of carnivores.","authors":"K C Hayes, B Schiefer","doi":"10.1177/030098586900600202","DOIUrl":"https://doi.org/10.1177/030098586900600202","url":null,"abstract":"Nineteen primary tumors of the central nervous system from dogs and 4 from cats are described. In the group of dogs, 15 were from brachycephalic breeds and 10 of these were boxers. Their tumors included 3 glioblastomas, 3 oligodendrogliomas, 3 astrocytomas, 3 ependymomas, 2 medulloblastomas, 4 meningiomas, and 1 malignant meningioma. One ependymoma and 1 meningioma were located in the spinal cord. The 4 neoplasms from cats were meningiomas.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 2","pages":"94-116"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15416934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600502
J M Lamas da Silva, H E Adler
Gross and microscopic changes of the joint, heart, and brain were studied in chickens infected intravenously with M. gallisepticum (S6 isolate). Synovitis occurred within 3 days, followed by suppurative arthritis at 7 days, and osteomyelitis 5 days later. The pathologic changes were attributed to a severe vasculitis characterized by extensive fibrinoid necrosis and endothelial swelling. Ischemic change was observed in the heart and brain as a result of the acute arteritis.
{"title":"Pathogenesis of arthritis induced in chickens by Mycoplasma gallisepticum.","authors":"J M Lamas da Silva, H E Adler","doi":"10.1177/030098586900600502","DOIUrl":"https://doi.org/10.1177/030098586900600502","url":null,"abstract":"Gross and microscopic changes of the joint, heart, and brain were studied in chickens infected intravenously with M. gallisepticum (S6 isolate). Synovitis occurred within 3 days, followed by suppurative arthritis at 7 days, and osteomyelitis 5 days later. The pathologic changes were attributed to a severe vasculitis characterized by extensive fibrinoid necrosis and endothelial swelling. Ischemic change was observed in the heart and brain as a result of the acute arteritis.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 5","pages":"385-95"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16452613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600504
K M Herrold
The adenocarcinomas of the intestine induced in Syrian hamsters by N-methyl-N-nitrosourea (NMU) were of two histological types, superficial and intestinal. These types had distinctive characteristics regarding pattern, cytological features, secretion of mucus, and mode of growth. The histological changes induced by NMU in the mucosa of the small intestine differed from what has been described in enzootic intestinal adenocarcinoma and proliferative ileitis of Syrian hamsters. NMU produced alteration in the villous architecture and cytological change in the absorptive cells. There was marked shortening of the villi and reduced thickness of the mucosa. The villous absorptive cells were large and cuboidal with centrally placed nuclei.
{"title":"Adenocarcinomas of the intestine induced in Syrian hamsters by N-methyl-N-nitrosourea.","authors":"K M Herrold","doi":"10.1177/030098586900600504","DOIUrl":"https://doi.org/10.1177/030098586900600504","url":null,"abstract":"The adenocarcinomas of the intestine induced in Syrian hamsters by N-methyl-N-nitrosourea (NMU) were of two histological types, superficial and intestinal. These types had distinctive characteristics regarding pattern, cytological features, secretion of mucus, and mode of growth. The histological changes induced by NMU in the mucosa of the small intestine differed from what has been described in enzootic intestinal adenocarcinoma and proliferative ileitis of Syrian hamsters. NMU produced alteration in the villous architecture and cytological change in the absorptive cells. There was marked shortening of the villi and reduced thickness of the mucosa. The villous absorptive cells were large and cuboidal with centrally placed nuclei.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 5","pages":"403-12"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600504","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16452614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600509
T E Staley, E W Jones, L D Corley
Laminated crystalline structures occurred within vacuoles of absorptive intestinal cells in colostrum-fed pigs. They are believed to be bilirubin crystals formed by breakdown of ingested red blood cells, but this could not be substantiated histochemically, and they could not be produced experimentally.
{"title":"Crystals in the intestinal epithelium of neonatal pigs.","authors":"T E Staley, E W Jones, L D Corley","doi":"10.1177/030098586900600509","DOIUrl":"https://doi.org/10.1177/030098586900600509","url":null,"abstract":"Laminated crystalline structures occurred within vacuoles of absorptive intestinal cells in colostrum-fed pigs. They are believed to be bilirubin crystals formed by breakdown of ingested red blood cells, but this could not be substantiated histochemically, and they could not be produced experimentally.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 5","pages":"454-62"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600509","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16452618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600203
L Clark, A A Seawright
Seven casts of generalised amyloidosis in the cat, occurring in 100 consecutive cat autopsies, were studied pathologically. Tissues from 2 of the cats were further investigated using the electron microscope. None of the cats had suffered from a prolonged infection, but one had had chronic allergic dermatitis. In 6 of the 7 cats chronic hypervitaminosis A coexisted with generalised amyloidosis. It is suggested that chronic hypervitaminosis A, which causes prolonged stimulation of the reticulo-endothelial system, may have predisposed to the high incidence of generalised amyloidosis reported in this paper.
{"title":"Generalised amyloidosis in seven cats.","authors":"L Clark, A A Seawright","doi":"10.1177/030098586900600203","DOIUrl":"https://doi.org/10.1177/030098586900600203","url":null,"abstract":"Seven casts of generalised amyloidosis in the cat, occurring in 100 consecutive cat autopsies, were studied pathologically. Tissues from 2 of the cats were further investigated using the electron microscope. None of the cats had suffered from a prolonged infection, but one had had chronic allergic dermatitis. In 6 of the 7 cats chronic hypervitaminosis A coexisted with generalised amyloidosis. It is suggested that chronic hypervitaminosis A, which causes prolonged stimulation of the reticulo-endothelial system, may have predisposed to the high incidence of generalised amyloidosis reported in this paper.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 2","pages":"117-34"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16470425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1969-01-01DOI: 10.1177/030098586900600404
H J Van Kruiningen, F M Garner, B Schiefer
This is the first report of a spontaneous case of protothecosis in the dog, an infection with organisms of the algal genus Prototheca. Clinically the animal had chronic bilateral iritis accompanied by glaucoma of one eye and hypotony of the other, chronic nephritis, arthritis, and bloody diarrhea. Lesions containing the algae occurred in myocardium, liver, kidneys, para-adrenal connective tissue, brain, and eyes.
{"title":"Protothecosis in a dog.","authors":"H J Van Kruiningen, F M Garner, B Schiefer","doi":"10.1177/030098586900600404","DOIUrl":"https://doi.org/10.1177/030098586900600404","url":null,"abstract":"This is the first report of a spontaneous case of protothecosis in the dog, an infection with organisms of the algal genus Prototheca. Clinically the animal had chronic bilateral iritis accompanied by glaucoma of one eye and hypotony of the other, chronic nephritis, arthritis, and bloody diarrhea. Lesions containing the algae occurred in myocardium, liver, kidneys, para-adrenal connective tissue, brain, and eyes.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 4","pages":"348-54"},"PeriodicalIF":0.0,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600404","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16473547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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