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Preparation the family to care of the patient with Alzhaimer's disease. 让家人做好照顾阿尔茨海默病患者的准备。
M Cisek, E Wilczek-Ruzyczka, A Gniadek, A Zdanowska

Purpose: Evaluation of the level of the family readiness to look after a person suffering from the Alzheimer's disease.

Material and methods: In the research an authorized questionnaire was used, which comprised knowledge concerning the disease, coping with the situation, looking after a patient and an open test.

Results: It was shown that the level of knowledge about Alzheimer's disease corresponds to the level of education (p < 0.05). Most families 67% look after the patient in their own houses, although they don't belong to any support group. Adapting to a new situation is difficult for people, although, most of them devote most of their energy to the patient with the support of the other members of the family. Family support and the level of knowledge aren't related with the patient acceptance (p < 0.05).

Conclusions: Family support and the level of knowledge aren't related with the patient acceptance. There is a relation, however, between the education and the level of knowledge about the Alzheimer's disease.

目的:评估家庭准备照顾患有阿尔茨海默病的人的水平。材料和方法:在研究中,使用了一份授权问卷,其中包括对疾病的了解,应对情况,照顾病人和公开测试。结果:老年痴呆症知识水平与受教育程度相对应(p < 0.05)。大多数家庭(67%)在自己家里照顾病人,尽管他们不属于任何支持团体。对人们来说,适应一个新的环境是很困难的,尽管他们中的大多数人在其他家庭成员的支持下,把大部分精力都投入到病人身上。家庭支持、知识水平与患者接受程度无显著相关(p < 0.05)。结论:家庭支持和知识水平与患者接受程度无关。然而,教育程度和对阿尔茨海默病的了解程度是有关系的。
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引用次数: 0
Quality of life, depressive symptoms and anxiety in hyperthyroid patients. 甲状腺机能亢进患者的生活质量、抑郁症状和焦虑
A Suwalska, K Lacka, D Lojko, J K Rybakowski

Purpose: The aim of the study was to evaluate quality of life and to assess frequency and severity of depressive and anxiety symptoms in hyperthyroid patients.

Material and methods: Forty-seven hyperthyroid patients (38 female, 9 male, mean age 51.4 +/- 13.0; 25-Graves disease, 22 - nodular goitre) and fifty-eight sex- and age-matched controls (40 female, 18 male, mean age 49.6 +/- 16.0) were studied. Quality of life was assessed by means of WHO QuoL Questionnaire. Psychometric evaluation included assessment of depressive symptoms (Hamilton Depression Rating Scale and Beck Depression Inventory) and anxiety level (State and Trait Anxiety Inventory--STAI).

Results: Patients presented significantly decreased perception of quality of life and health state, and scored worse in physical domain and global score of WHO QuoL. Nineteen patients showed depressive symptoms, remaining 28 were euthymic. Level of anxiety did not differ significantly between the patients group and controls. Free thyroxine plasma level correlated with psychological domain of QuoL. Depression severity correlated with anxiety (STAI 2). Anxiety as a state marker influenced psychological and environmental domains and global score of quality of life questionnaire.

Conclusions: The influence of hyperthyroidism on the quality of life was observed. Depressive symptoms are frequent in hyperthyroidism, occurring in 40% hyperthyroid patients. We found also the association between the anxiety level and the quality of life.

目的:本研究的目的是评估甲状腺功能亢进患者的生活质量以及抑郁和焦虑症状的频率和严重程度。材料与方法:甲状腺功能亢进患者47例,其中女性38例,男性9例,平均年龄51.4±13.0岁;研究了25例graves病(22例结节性甲状腺肿)和58例性别和年龄匹配的对照组(女性40例,男性18例,平均年龄49.6±16.0岁)。采用世界卫生组织生活质量问卷(WHO QuoL Questionnaire)评价患者的生活质量。心理测量评估包括抑郁症状(汉密尔顿抑郁评定量表和贝克抑郁量表)和焦虑水平(状态和特质焦虑量表——STAI)的评估。结果:患者对生活质量和健康状况的感知明显下降,身体领域和WHO QuoL总体得分较差。19例患者表现为抑郁症状,其余28例患者表现为心境平和。焦虑水平在患者组和对照组之间没有显著差异。血浆游离甲状腺素水平与QuoL心理域相关。抑郁严重程度与焦虑相关(STAI 2)。焦虑作为一种状态标记影响心理和环境领域以及生活质量问卷的整体得分。结论:观察甲亢对患者生活质量的影响。甲状腺机能亢进患者常出现抑郁症状,40%甲状腺机能亢进患者出现抑郁症状。我们还发现了焦虑程度和生活质量之间的联系。
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引用次数: 0
The influence of the dietary habit on lipoprotein density in blood serum of men from Podlasie region. 饮食习惯对波哥大地区男性血清脂蛋白密度的影响。
K Witana, R J Nowak, A Szpak, A Genowska

In the years 1987-1998 we conducted examined a group of 556 men three times. The nutritional status was evaluated as well as total cholesterol, HDL- and LDL-cholesterol and triglycerides concentration in blood serum and it allowed to evaluate the influence of nutrition on lipid status. The relationships between diet composition and lipid levels in the whole period of 9 years were evaluated using multidimensional linear regression analysis. Among examined men, depending on the period of the study, values of serum total cholesterol (C <200 mg/dk) favourable from the standpoint of arteriosclerosis prevention were noted in only 36-39%, with LDL-cholesterol below 130 mg/dl in 35-48%, HDL-cholesterol over 35 mg/dl in 87-94% and triglyceride levels below 200 mg/dl in 81-83% of the studied men. Among 6 basic nutrients of the diet, only plant fat was significantly influencing the concentration of triglycerides in blood serum--an increase of its consumption caused the decrease of triglyceride level. It has been proven that increasing amount of alcohol in the diet led to the increase of HDL-cholesterol in blood serum. Blood serum lipids were significantly influenced by BMI. Increased body mass index significantly influenced the concentration of total cholesterol, LDL-cholesterol and triglycerides in blood serum. In examined men with the increase of body mass index the HDL-cholesterol concentration was decreasing. Summing it up-it has been shown that the diet of examined men directly and significantly influenced lipid concentration in blood serum, and it also had an indirect influence on lipid concentration, through body mass regulation, which significantly influenced its concentration.

1987-1998年间,我们对556名男性进行了三次检查。评估营养状况以及血清中总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯浓度,从而评估营养对血脂状况的影响。采用多维线性回归分析评价9年期间饮食组成与血脂水平的关系。在接受调查的男性中,根据研究的时间,血清总胆固醇(C
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引用次数: 0
The occurrence of pulmonary hypertension in patients with systemic sclerosis hospitalized in the Department of Rheumatology and Internal Diseases Medical University of Białystok in years 2003-2004. 2003-2004年Białystok医科大学风湿病内科住院的系统性硬化症患者肺动脉高压的发生。
E Gińdzieńska-Sieśkiewicz, O Kowal-Bielecka, J Kita, A Lisowska, I Domysławska, W Musiał, S Sierakowski

Pulmonary hypertension (PH) is one the most fatal complications of systemic sclerosis (SSc). The aim of the present study was to investigate the occurrence of PH in SSc patients hospitalized in Department of Rheumatology and Internal Diseases University Hospital of Bialystok in years 2003-2004. PH was defined as pulmonary artery systolic pressure (PASP) higher than 35 mmHg as evaluated by ECHO-Doppler. We found PH in 23 out of 53 (43%) SSc patients included in the study. In the majority of patients 20/23 (87%) PH coexisted with the presence of scleroderma lung disease as evaluated by high resolution computed tomography of the lungs. In the remaining 3/23 (13%) patients isolated (arterial) PH was detected. Patients with isolated PH tend to have higher values of PASP (82 +/- 39.0 mmHg) than those with PH and interstitial lung disease (42.5 +/- 6.4 mmHg). The results of our study indicate that PH is a frequent complication of SSc.

肺动脉高压(PH)是系统性硬化症(SSc)最致命的并发症之一。本研究的目的是调查2003-2004年在比亚韦斯托克大学医院风湿病和内科住院的SSc患者PH的发生情况。超声多普勒评价肺动脉收缩压(PASP)高于35mmhg即为PH。我们在纳入研究的53例(43%)SSc患者中发现23例PH。通过肺部高分辨率计算机断层扫描评估,在大多数患者中,20/23(87%)的PH与硬皮病并存。在其余3/23(13%)的患者中检测到分离的(动脉)PH。孤立性PH患者的PASP值(82 +/- 39.0 mmHg)往往高于PH合并间质性肺病患者(42.5 +/- 6.4 mmHg)。我们的研究结果表明,PH是SSc的常见并发症。
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引用次数: 0
Quality of life in healthy children and in children with tension headaches--a comparative analysis. 健康儿童与紧张性头痛儿童的生活质量比较分析
D Talarska

Purpose: The aim of this study was the assessment of the quality of life of children and adolescents with tension headaches in comparison with healthy peers.

Material and methods: The study was conducted on 135 middle school and high school students in Poznań and on 86 children with tension headaches, that were treated in the out-patient clinic of The Chair and Clinic of Development Age Neurology of Karol Marcinkowski University of Medical Sciences in Poznań. The research tool for both groups was Pediatric Quality of Life Inventory, version 4.0 (PedsQL 4.0) questionnaire.

Results: In the analysed groups dominated 14- and 16-year-old children. Among children with tension headaches, the ailments usually appeared once or twice a week in 39 (45%) of them. With the use of the PedsQL 4.0 questionnaire the following fields of activity were analyzed: biological, emotional, social functioning and mood.

Conclusions: The biggest discrepancies between the group of healthy children and those with headaches were noted in the field of emotional functioning and mood. Adolescents with tension headaches more frequently reported the feeling of fear and sleep disorders in comparison to healthy students. Children with headaches look at the future in a more pessimistic way and are less satisfied with their lives.

目的:本研究的目的是评估患有紧张性头痛的儿童和青少年与健康同龄人的生活质量。材料与方法:研究对象为波兹纳斯基Karol Marcinkowski医科大学The Chair and The clinic of Development Age Neurology门诊治疗的135名波兹纳斯基初高中学生和86名紧张性头痛儿童。两组的研究工具均为儿童生活质量量表4.0版(PedsQL 4.0)问卷。结果:在分析组中以14岁和16岁儿童为主。在患有紧张性头痛的儿童中,39名(45%)儿童的疾病通常每周出现一次或两次。使用PedsQL 4.0问卷分析以下活动领域:生物、情感、社会功能和情绪。结论:健康儿童与头痛儿童在情绪功能和心境方面差异最大。与健康的学生相比,患有紧张性头痛的青少年更容易感到恐惧和睡眠障碍。患有头痛的孩子看待未来的方式更悲观,对自己的生活不太满意。
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引用次数: 0
Quality of life after surgical treatment of thyroid gland diseases. 甲状腺疾病手术治疗后的生活质量。
B Wojewoda, J Juzwiszyn, J Rosińczuk-Tonderys

Purpose: The aim of the work is to rate different factors specifying quality of life after surgical treatment of thyroid gland diseases.

Material and methods: Research was carried out on 93 people with recognition of nodular goitre treated surgically during the period 2000-2003 in 2nd Department of General and Oncological Surgery in Wrocław. 83 women and 10 men aged approximately 48 took part in the research. The research was carried out with a help of analysis of medical documentation as well as QL questionnaire including 25 features (clinical, emotional, social). The results of the QL research were prepared on the basis of "SyntMed" Computer Medical Diagnostics programme (Krefft method). Every patient was given a certain QL quantity in the 0-1 range together with the importance of diagnostic features, indicating the strength of influence of the feature on QL quantity.

Results: The strongest influence on QL index had the following diagnostic features: subjective opinion of the quality of life (0.674), sensation of fear in connection with the health condition (0.631), physical efficiency (0.565). Among clinical features the strongest influence had a feeling of palpitation (0.405). It was certified that together with the extension of the post-operation period medium value of QL index increases. The most frequent clinical problems mentioned by the tested patients were: sleeping disorder (66.6%), nervousness (37.6%), sweating (36.5%), palpitation (24.7%). 36.6% of the tested patients are afraid of a setback and 77.4 % of them are worried about their health condition. The treatment did not have an influence on planning the future, sexuality and social life. 59.1% of the tested patients defined their present health condition as satisfactory.

目的:评价影响甲状腺疾病手术治疗后生活质量的因素。材料与方法:对Wrocław普通肿瘤外科二科2000-2003年收治的93例经手术治疗的结节性甲状腺肿患者进行研究。年龄在48岁左右的83名女性和10名男性参与了这项研究。本研究借助医学文献分析以及包含25个特征(临床、情感、社会)的QL问卷进行。QL的研究结果是在“SyntMed”计算机医学诊断程序(Krefft法)的基础上编制的。每个患者在0-1范围内给出一定的QL值,并给出诊断特征的重要性,表明该特征对QL值的影响程度。结果:对QL指数影响最大的诊断特征为:生活质量主观评价(0.674)、与健康状况相关的恐惧感觉(0.631)、身体效率(0.565)。在临床特征中,影响最大的是心悸感(0.405)。结果表明,随着术后时间的延长,QL指标的中值逐渐增大。受访患者最常提到的临床问题是:睡眠障碍(66.6%)、神经紧张(37.6%)、出汗(36.5%)、心悸(24.7%)。36.6%的受测者害怕挫折,77.4%的受测者担心自己的健康状况。治疗对计划未来、性行为和社会生活没有影响。59.1%的患者认为自己目前的健康状况是满意的。
{"title":"Quality of life after surgical treatment of thyroid gland diseases.","authors":"B Wojewoda,&nbsp;J Juzwiszyn,&nbsp;J Rosińczuk-Tonderys","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the work is to rate different factors specifying quality of life after surgical treatment of thyroid gland diseases.</p><p><strong>Material and methods: </strong>Research was carried out on 93 people with recognition of nodular goitre treated surgically during the period 2000-2003 in 2nd Department of General and Oncological Surgery in Wrocław. 83 women and 10 men aged approximately 48 took part in the research. The research was carried out with a help of analysis of medical documentation as well as QL questionnaire including 25 features (clinical, emotional, social). The results of the QL research were prepared on the basis of \"SyntMed\" Computer Medical Diagnostics programme (Krefft method). Every patient was given a certain QL quantity in the 0-1 range together with the importance of diagnostic features, indicating the strength of influence of the feature on QL quantity.</p><p><strong>Results: </strong>The strongest influence on QL index had the following diagnostic features: subjective opinion of the quality of life (0.674), sensation of fear in connection with the health condition (0.631), physical efficiency (0.565). Among clinical features the strongest influence had a feeling of palpitation (0.405). It was certified that together with the extension of the post-operation period medium value of QL index increases. The most frequent clinical problems mentioned by the tested patients were: sleeping disorder (66.6%), nervousness (37.6%), sweating (36.5%), palpitation (24.7%). 36.6% of the tested patients are afraid of a setback and 77.4 % of them are worried about their health condition. The treatment did not have an influence on planning the future, sexuality and social life. 59.1% of the tested patients defined their present health condition as satisfactory.</p>","PeriodicalId":79372,"journal":{"name":"Roczniki Akademii Medycznej w Bialymstoku (1995)","volume":"50 Suppl 1 ","pages":"133-6"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25266177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An older person as a subject of comprehensive geriatric approach. 将老年人作为综合老年医学方法的研究对象。
B Bieiń

The simultaneous presence of many disorders (physical, psychological, and social) and unmet health care needs in elderly people require a more complex assessment then just a routine diagnostic examination. The involvement of comprehensive geriatric assessment provides a health care model that integrates medical and nursing care with social support. A geriatric assessment could be carried out in a wide variety of settings including: acute hospital units, long-term care, out-patient dispensaries and home visits. A holistic and comprehensive geriatric approach should cover physical, functional and mental assessments as well as the caregiver's strain. For preventive care, effort should be placed on the aspect of health promotion, diseases prevention, and disability postponement. Rehabilitation is an important area for older people, as a majority of them requires a temporary rehabilitation after a major illness before they could regain independence in the community. In order to provide a cross comparison among different patients in different settings, a standardized methodology or instruments will enable to make comparisons better then subjective investigation. To provide a holistic and interdisciplinary health care for the elderly, training doctors, nurses and other health care professionals in geriatrics and gerontology is essential.

老年人同时存在许多疾病(身体、心理和社会)和未满足的卫生保健需求,需要进行比常规诊断检查更复杂的评估。全面的老年评估提供了一种将医疗和护理与社会支持相结合的保健模式。可以在各种各样的环境中进行老年评估,包括:急症病房、长期护理、门诊诊所和家访。全面和全面的老年病学方法应包括身体、功能和精神评估以及照顾者的压力。预防性保健应从促进健康、预防疾病和延缓残疾等方面着手。康复是老年人的一个重要领域,因为大多数老年人在患重大疾病后需要暂时康复,才能在社区中重新获得独立。为了在不同情况下的不同患者之间进行交叉比较,标准化的方法或工具将使比较比主观调查更好。为了向老年人提供全面和跨学科的保健服务,必须对医生、护士和其他保健专业人员进行老年病学和老年学方面的培训。
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引用次数: 0
Surgical nurses and their concerns of acquiring HIV infection at the workplace. 外科护士及其对工作场所感染艾滋病毒的担忧。
M Milona, M Gańczak, Z Szych

A study was conducted to identify pertaining to the care of HIV infected patients among nurses in the County of West Pomerania. Most of the respondents (43.2%) were working in municipal hospitals, 38.7% in hospitals located in the country and 18% in academic hospitals. The responding nurses ranged in age from 20 to 58 (median 38 years). Median of work experience was 16 (1-28) years. The respondents were divided into 3 groups: A--the nurses who expressed serious concern about HIV infection, 62.9%; B--some degree of concern, 31.3%; C--not concerned, 4.3%. An HIV/AIDS workshop was attended by 74.6% of respondents from group A and 76.6% from group B (p > 0.85). The occupational exposure reported 49.5% nurses from group A, 39.9% from group B and 42.4% from group C (p > 0.3). The gloves were "always" used by 82.5% respondents from group A, 87.8% from group B and 76.9% from group C (p > 0.07). 79.9% of nurses from group A, 53.2% from group B and 42.3% (p < 0.0001) favored HIV antibodies testing of all patients.

进行了一项研究,以确定西波美拉尼亚县护士对艾滋病毒感染患者的护理情况。大多数受访者(43.2%)在市级医院工作,38.7%在全国医院工作,18%在学术医院工作。受访护士年龄20 ~ 58岁,中位年龄38岁。工作经验中位数为16(1-28)年。受访者分为3组:A组——对HIV感染表示严重担忧的护士占62.9%;B——有一定程度的担忧,31.3%;C——不关心,4.3%。参加HIV/AIDS研讨会的A组和B组分别为74.6%和76.6% (p > 0.85)。A组护士职业暴露率为49.5%,B组为39.9%,C组为42.4% (p > 0.3)。A组82.5%、B组87.8%、C组76.9%的人“总是”使用手套(p > 0.07)。79.9%的A组护士、53.2%的B组护士和42.3% (p < 0.0001)的护士赞成对所有患者进行HIV抗体检测。
{"title":"Surgical nurses and their concerns of acquiring HIV infection at the workplace.","authors":"M Milona,&nbsp;M Gańczak,&nbsp;Z Szych","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study was conducted to identify pertaining to the care of HIV infected patients among nurses in the County of West Pomerania. Most of the respondents (43.2%) were working in municipal hospitals, 38.7% in hospitals located in the country and 18% in academic hospitals. The responding nurses ranged in age from 20 to 58 (median 38 years). Median of work experience was 16 (1-28) years. The respondents were divided into 3 groups: A--the nurses who expressed serious concern about HIV infection, 62.9%; B--some degree of concern, 31.3%; C--not concerned, 4.3%. An HIV/AIDS workshop was attended by 74.6% of respondents from group A and 76.6% from group B (p > 0.85). The occupational exposure reported 49.5% nurses from group A, 39.9% from group B and 42.4% from group C (p > 0.3). The gloves were \"always\" used by 82.5% respondents from group A, 87.8% from group B and 76.9% from group C (p > 0.07). 79.9% of nurses from group A, 53.2% from group B and 42.3% (p < 0.0001) favored HIV antibodies testing of all patients.</p>","PeriodicalId":79372,"journal":{"name":"Roczniki Akademii Medycznej w Bialymstoku (1995)","volume":"50 Suppl 1 ","pages":"203-6"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25265420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence and clinical significance of antiphospholipid antibodies in the patients with systemic sclerosis--preliminary report. 系统性硬化症患者抗磷脂抗体的流行及临床意义——初步报告。
A Sulik, O Kowal-Bielecka, I Domysławska, J Chwiećko, S Sierakowski

Purpose: The aim of our study was to evaluate the prevalence of anticardiolipin and anti-beta2-glikoprotein I (anti-beta2GPI) antibodies in patients with systemic sclerosis (SSc) and to correlate the presence of these antibodies with clinical and serological features of the disease.

Material and methods: 22 patients (21 women and 1 man) fulfilling the ACR classification criteria of SSc were included into the study. In all SSc patients a detailed clinical evaluation including skin and internal organ involvement was performed. Moreover, the measurements of antitopoisomerase I (anti-Scl-70) and anticentromere (ACA) antibodies were done in all patients studied. Anticardiolipin antibodies in IgM and IgG class and anti-beta2GPI antibodies in IgM, IgG and IgA class were evaluated using ELISA kits (Hycor Biomedical and DiaSorin).

Results: Anticardiolipin antibodies were found in 10/22 (45.5%) patients with SSc, in 6/12 (50%) with diffuse SSc and in 4/10 (40%) with the limited SSc. Anticardiolipin antibodies in the IgG class were observed in 4/22 (18.2%) patients, and in the IgM class in 9/22 (40.9%) subjects. Anti-beta2GPI antibodies were found in 9/22 patients (40.9%), of which 3/22 (13.6%) had antibodies in IgG class, 4/22 (18.2%) in IgM class and 3/22 (13.6%) in the IgA class. Anti-beta2GPI antibodies were found exclusively in the patients in whom the anticardiolipin antibodies were also present. An association between the presence of antiphospholipid antibodies and internal organ involvement (pulmonary fibrosis, pulmonary hypertension and the alterations of oesophageal function) was not significant. No significant correlation was found between the presence of anticardiolipin or anti-beta2GPI antibodies and the presence of anti-Scl-70 or ACA antibodies.

Conclusions: The results of our study indicate that the prevalence of anticardiolipin antibodies and anti-beta2GPI antibodies is relatively high in patients with SSc. A more detailed assessment of the relationship between the presence of antiphospholipid antibodies and the clinical and serological features of SSc requires further studies on the larger group of patients and a several years of follow-up.

目的:本研究的目的是评估系统性硬化症(SSc)患者中抗心磷脂和抗β 2-糖样蛋白I(抗β 2- gpi)抗体的患病率,并将这些抗体的存在与该疾病的临床和血清学特征联系起来。材料与方法:纳入符合ACR分级标准的SSc患者22例(女21例,男1例)。所有SSc患者都进行了详细的临床评估,包括皮肤和内脏器官的受累情况。此外,在所有研究的患者中都进行了抗拓扑异构酶I(抗scl -70)和抗着丝粒(ACA)抗体的测量。采用ELISA试剂盒(Hycor Biomedical和DiaSorin)检测IgM、IgG类抗心磷脂抗体和IgM、IgG、IgA类抗β 2gpi抗体。结果:10/22 (45.5%)SSc、6/12(50%)弥漫性SSc和4/10(40%)局限性SSc患者检测到抗心磷脂抗体。4/22(18.2%)患者出现IgG类抗心磷脂抗体,9/22(40.9%)患者出现IgM类抗心磷脂抗体。9/22例患者(40.9%)存在抗β - 2gpi抗体,其中3/22例(13.6%)存在IgG类抗体,4/22例(18.2%)存在IgM类抗体,3/22例(13.6%)存在IgA类抗体。抗β 2gpi抗体仅在同时存在抗心磷脂抗体的患者中发现。抗磷脂抗体的存在与内脏器官受损伤(肺纤维化、肺动脉高压和食管功能改变)之间的关联不显著。抗心磷脂或抗β 2gpi抗体的存在与抗scl -70或ACA抗体的存在之间没有明显的相关性。结论:我们的研究结果表明,SSc患者抗心磷脂抗体和抗β 2gpi抗体的患病率较高。更详细地评估抗磷脂抗体的存在与SSc的临床和血清学特征之间的关系,需要对更大的患者群体进行进一步的研究,并进行数年的随访。
{"title":"The prevalence and clinical significance of antiphospholipid antibodies in the patients with systemic sclerosis--preliminary report.","authors":"A Sulik,&nbsp;O Kowal-Bielecka,&nbsp;I Domysławska,&nbsp;J Chwiećko,&nbsp;S Sierakowski","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of our study was to evaluate the prevalence of anticardiolipin and anti-beta2-glikoprotein I (anti-beta2GPI) antibodies in patients with systemic sclerosis (SSc) and to correlate the presence of these antibodies with clinical and serological features of the disease.</p><p><strong>Material and methods: </strong>22 patients (21 women and 1 man) fulfilling the ACR classification criteria of SSc were included into the study. In all SSc patients a detailed clinical evaluation including skin and internal organ involvement was performed. Moreover, the measurements of antitopoisomerase I (anti-Scl-70) and anticentromere (ACA) antibodies were done in all patients studied. Anticardiolipin antibodies in IgM and IgG class and anti-beta2GPI antibodies in IgM, IgG and IgA class were evaluated using ELISA kits (Hycor Biomedical and DiaSorin).</p><p><strong>Results: </strong>Anticardiolipin antibodies were found in 10/22 (45.5%) patients with SSc, in 6/12 (50%) with diffuse SSc and in 4/10 (40%) with the limited SSc. Anticardiolipin antibodies in the IgG class were observed in 4/22 (18.2%) patients, and in the IgM class in 9/22 (40.9%) subjects. Anti-beta2GPI antibodies were found in 9/22 patients (40.9%), of which 3/22 (13.6%) had antibodies in IgG class, 4/22 (18.2%) in IgM class and 3/22 (13.6%) in the IgA class. Anti-beta2GPI antibodies were found exclusively in the patients in whom the anticardiolipin antibodies were also present. An association between the presence of antiphospholipid antibodies and internal organ involvement (pulmonary fibrosis, pulmonary hypertension and the alterations of oesophageal function) was not significant. No significant correlation was found between the presence of anticardiolipin or anti-beta2GPI antibodies and the presence of anti-Scl-70 or ACA antibodies.</p><p><strong>Conclusions: </strong>The results of our study indicate that the prevalence of anticardiolipin antibodies and anti-beta2GPI antibodies is relatively high in patients with SSc. A more detailed assessment of the relationship between the presence of antiphospholipid antibodies and the clinical and serological features of SSc requires further studies on the larger group of patients and a several years of follow-up.</p>","PeriodicalId":79372,"journal":{"name":"Roczniki Akademii Medycznej w Bialymstoku (1995)","volume":"50 Suppl 1 ","pages":"228-31"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25264176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge of risk factors and guidelines for the management of asthma. The educational role of the nurse. 了解哮喘的危险因素和治疗指南。护士的教育作用。
C Dolińska, Z Zietkowski, A Bodzenta-Lukaszyk

Purpose: The aim of the study was to determine the level of knowledge concerning risk factors for the development of asthma and worsening of the course of the disease among patients, as well as achieving a better understanding of the educational role of the nurse in improving the quality of life of patients suffering from the disease.

Materials and methods: The study was a questionnaire study involving 100 patients suffering from asthma. 59 of them were diagnosed as having an allergic and 41 a nonallergic asthma. In the main they were patients suffering from moderate to severe asthma, who had attended the outpatient allergology clinic for many years.

Results: Analysis of the results obtained demonstrated the significant effects of asthma for the lives and health of the patients questioned. This was reflected in the high number of people registered as unable to work and receiving invalidity benefits, and influenced the activity of the majority patients in various spheres of life. A number of respondents demonstrated poor knowledge of the risk factors for asthma and ways of eliminating the illness. The majority of patients had a good knowledge of the names, doses and ways in which they should take their prescribed medication as well as showing an understanding of the principles of taking additional medicines as necessary. Their knowledge of the principles of anti-inflammatory treatment, which is a basic factor in the treatment of patients with asthma was, however very poor.

Conclusions: Among patients suffering from asthma there is a great need for health information. The majority of respondents expressed a willingness to take part in training sessions to be run by nursing staff. The focus of these educational sessions should be on improving the patients' knowledge about asthma as a chronic inflammatory disease, helping to eliminate and limit risk factors for the disease, treatment principles and avoiding the side-effects of prescribed medication.

目的:本研究的目的是确定患者对哮喘发展和病程恶化的危险因素的了解程度,以及更好地了解护士在改善哮喘患者生活质量方面的教育作用。材料与方法:采用问卷调查法对100例哮喘患者进行研究。其中59人被诊断为过敏性哮喘,41人被诊断为非过敏性哮喘。他们主要是患有中度至重度哮喘的患者,他们在门诊过敏诊所就诊多年。结果:结果分析表明哮喘对被调查患者的生命和健康有显著影响。这反映在登记为不能工作和领取伤残津贴的人数众多,并影响到大多数病人在生活各个领域的活动。许多答复者表现出对哮喘的危险因素和消除这种疾病的方法知之甚少。大多数患者对处方药物的名称、剂量和服用方法有很好的了解,并了解必要时服用额外药物的原则。然而,他们对抗炎治疗原理的了解非常少,而抗炎治疗是治疗哮喘患者的基本因素。结论:哮喘患者对健康信息的需求很大。大多数受访者表示愿意参加由护理人员举办的培训课程。这些教育课程的重点应该是提高患者对哮喘作为一种慢性炎症性疾病的认识,帮助消除和限制疾病的危险因素,治疗原则和避免处方药的副作用。
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引用次数: 0
期刊
Roczniki Akademii Medycznej w Bialymstoku (1995)
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