Pub Date : 2025-12-15eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004603
Hasibullah Aminpoor, Muhammad Khizar, Muhammad Zaib, Abeer Ijaz, Hasiba Karimi
Single-incision robotic surgery (SIRS) has emerged as a progression in minimally invasive practice, enabling complex operations through a single entry point. Modern systems such as the da Vinci SP (Intuitive Surgical, USA) and Versius (CMR Surgical, UK) allow multi-instrument articulation and high-definition visualization through a single port, overcoming the ergonomic and triangulation challenges of traditional laparoscopy. Recent evidence from South Korea, China, the USA, and Turkey demonstrates SIRS's feasibility, safety, and promising clinical outcomes across specialties including urology, gynecology, and general surgery. Studies report lower conversion rates, minimal postoperative pain, and enhanced cosmesis, though cost and learning curve remain limiting factors. As robotic technologies evolve, SIRS is poised to redefine minimally invasive standards through precision, reduced invasiveness, and improved recovery profiles. Rigorous multicenter trials and cost-effectiveness analyses are essential to confirm its broader clinical value.
{"title":"Single-incision robotic surgery: the emerging milestone in minimally invasive practice.","authors":"Hasibullah Aminpoor, Muhammad Khizar, Muhammad Zaib, Abeer Ijaz, Hasiba Karimi","doi":"10.1097/MS9.0000000000004603","DOIUrl":"10.1097/MS9.0000000000004603","url":null,"abstract":"<p><p>Single-incision robotic surgery (SIRS) has emerged as a progression in minimally invasive practice, enabling complex operations through a single entry point. Modern systems such as the da Vinci SP (Intuitive Surgical, USA) and Versius (CMR Surgical, UK) allow multi-instrument articulation and high-definition visualization through a single port, overcoming the ergonomic and triangulation challenges of traditional laparoscopy. Recent evidence from South Korea, China, the USA, and Turkey demonstrates SIRS's feasibility, safety, and promising clinical outcomes across specialties including urology, gynecology, and general surgery. Studies report lower conversion rates, minimal postoperative pain, and enhanced cosmesis, though cost and learning curve remain limiting factors. As robotic technologies evolve, SIRS is poised to redefine minimally invasive standards through precision, reduced invasiveness, and improved recovery profiles. Rigorous multicenter trials and cost-effectiveness analyses are essential to confirm its broader clinical value.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1150-1151"},"PeriodicalIF":1.6,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The concept behind 4D morphing biopolymers represents a further improvement in reconstructive plastic surgery, as it can now create scaffolds that are stimulus-responsive, allowing them to exhibit flexibility in shape and functionality once implanted. Such materials have the potential to address the shortcomings of conventional autologous reconstruction through enhanced integration, vascularization, and minimally invasive implantation. Nevertheless, significant issues of translation, regulation, and ethics remain, underscoring the need for in vivo research, surgeon-engineer partnerships, and fair clinical practice.
{"title":"4D-Morphing biopolymers in reconstructive plastic surgery: implications, challenges and a call for clinical-translation.","authors":"Asra Amjad, Maryam Waqar, Umair Ali, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004537","DOIUrl":"10.1097/MS9.0000000000004537","url":null,"abstract":"<p><p>The concept behind 4D morphing biopolymers represents a further improvement in reconstructive plastic surgery, as it can now create scaffolds that are stimulus-responsive, allowing them to exhibit flexibility in shape and functionality once implanted. Such materials have the potential to address the shortcomings of conventional autologous reconstruction through enhanced integration, vascularization, and minimally invasive implantation. Nevertheless, significant issues of translation, regulation, and ethics remain, underscoring the need for in vivo research, surgeon-engineer partnerships, and fair clinical practice.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1126-1127"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004541
Asra Amjad, Armeen Shahzad, Ruben Simon Roy, Raghabendra Kumar Mahato, Umair Ali
{"title":"Unmasking the malignancy beneath: re-evaluating splenic pseudocysts as potential precursors of lymphoma.","authors":"Asra Amjad, Armeen Shahzad, Ruben Simon Roy, Raghabendra Kumar Mahato, Umair Ali","doi":"10.1097/MS9.0000000000004541","DOIUrl":"10.1097/MS9.0000000000004541","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1132-1133"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004566
Asra Amjad, Tooba Khurshid, Raghabendra Kumar Mahato, Umair Ali
{"title":"Critical appraisal of \"Evaluation of preoperative cervical internal carotid artery diameter as a predictor of cerebral hyperperfusion syndrome following revascularization surgery\".","authors":"Asra Amjad, Tooba Khurshid, Raghabendra Kumar Mahato, Umair Ali","doi":"10.1097/MS9.0000000000004566","DOIUrl":"10.1097/MS9.0000000000004566","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1146-1147"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004538
Asra Amjad, Muhammad Talha Usman, Umair Ali, Raghabendra Kumar Mahato
{"title":"Spatial confinement of the AREG-SOX9 signaling circuit: rethinking tumor-stroma interactions in gastric cancer.","authors":"Asra Amjad, Muhammad Talha Usman, Umair Ali, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004538","DOIUrl":"10.1097/MS9.0000000000004538","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1128-1129"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Photothermal nanoparticles delivering heat-triggered siRNA for tumor therapy.","authors":"Fahad Amin, Ayesha Imran, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004580","DOIUrl":"10.1097/MS9.0000000000004580","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1148-1149"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward precision correction of OTUD5-mediated deubiquitylation defect in LINKED syndrome: a gene-editing paradigm for embryonic chromatin-remodeller disorders.","authors":"Asra Amjad, Ghanwa Imran, Umair Ali, Raghabendra Kumar Mahato","doi":"10.1097/MS9.0000000000004540","DOIUrl":"10.1097/MS9.0000000000004540","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1130-1131"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-12eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004525
Ahmad Furqan Anjum, Ali Rizwan Faisal, Hermann Yokolo
{"title":"Correspondence: Atypical spinal infections in the era of multidrug resistance: knowledge gaps and a proposed management algorithm.","authors":"Ahmad Furqan Anjum, Ali Rizwan Faisal, Hermann Yokolo","doi":"10.1097/MS9.0000000000004525","DOIUrl":"10.1097/MS9.0000000000004525","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"1138-1139"},"PeriodicalIF":1.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145909700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004516
Asra Amjad, Heena Arshad, Raghabendra Kumar Mahato, Umair Ali
{"title":"Beyond hyperacusis: re-framing tonic tensor tympani syndrome as a middle-ear muscle dysregulation disorder in tinnitus clinics.","authors":"Asra Amjad, Heena Arshad, Raghabendra Kumar Mahato, Umair Ali","doi":"10.1097/MS9.0000000000004516","DOIUrl":"10.1097/MS9.0000000000004516","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"54-55"},"PeriodicalIF":1.6,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12767933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11eCollection Date: 2026-01-01DOI: 10.1097/MS9.0000000000004544
Amir Abadi, Usra Ghanem, Shaker Nierat, Marwan Joma
Introduction and importance: Kounis syndrome is a rare condition described by acute coronary syndrome following an allergic reaction. This case report highlights a unique presentation of Kounis syndrome following moxifloxacin ingestion in a patient with vasculitis and a history of smoking.
Case presentation: A 55-year-old male smoker with a history of vasculitis presented with acute chest pain 1 hour after moxifloxacin ingestion. The patient developed epigastric pain, dizziness, and sweating. ECG showed ST-segment elevation in leads II, III, and aVF. Initial lab work revealed elevated eosinophil and basophil counts consistent with an allergic reaction. Cardiac catheterization identified significant stenosis in the left anterior descending artery, which was managed with a stent and a balloon. The patient was treated with corticosteroids, antihistamines, and dual antiplatelet therapy. Eosinophil and basophil counts became normal, and the patient was discharged in a stable condition.
Clinical discussion: This case showcases the intersection between allergic reactions and coronary events. Moxifloxacin is a known trigger for Kounis syndrome. The patient's vasculitis and smoking history likely predisposed him to coronary inflammation, making him susceptible to Kounis syndrome. While Kounis syndrome remains underdiagnosed due to the overlapping symptoms, timely recognition and management addressing both the allergic and cardiac components are crucial.
Conclusion: This article highlights the importance of considering Kounis syndrome in patients presenting with ACS following an allergic reaction, particularly in those with predisposing factors. Prompt diagnosis and intervention are essential to improve outcomes.
{"title":"Post anaphylactic shock myocardial infarction (Kounis syndrome): a rare case report.","authors":"Amir Abadi, Usra Ghanem, Shaker Nierat, Marwan Joma","doi":"10.1097/MS9.0000000000004544","DOIUrl":"10.1097/MS9.0000000000004544","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Kounis syndrome is a rare condition described by acute coronary syndrome following an allergic reaction. This case report highlights a unique presentation of Kounis syndrome following moxifloxacin ingestion in a patient with vasculitis and a history of smoking.</p><p><strong>Case presentation: </strong>A 55-year-old male smoker with a history of vasculitis presented with acute chest pain 1 hour after moxifloxacin ingestion. The patient developed epigastric pain, dizziness, and sweating. ECG showed ST-segment elevation in leads II, III, and aVF. Initial lab work revealed elevated eosinophil and basophil counts consistent with an allergic reaction. Cardiac catheterization identified significant stenosis in the left anterior descending artery, which was managed with a stent and a balloon. The patient was treated with corticosteroids, antihistamines, and dual antiplatelet therapy. Eosinophil and basophil counts became normal, and the patient was discharged in a stable condition.</p><p><strong>Clinical discussion: </strong>This case showcases the intersection between allergic reactions and coronary events. Moxifloxacin is a known trigger for Kounis syndrome. The patient's vasculitis and smoking history likely predisposed him to coronary inflammation, making him susceptible to Kounis syndrome. While Kounis syndrome remains underdiagnosed due to the overlapping symptoms, timely recognition and management addressing both the allergic and cardiac components are crucial.</p><p><strong>Conclusion: </strong>This article highlights the importance of considering Kounis syndrome in patients presenting with ACS following an allergic reaction, particularly in those with predisposing factors. Prompt diagnosis and intervention are essential to improve outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"88 1","pages":"915-918"},"PeriodicalIF":1.6,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12768004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}