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Single-incision robotic surgery: the emerging milestone in minimally invasive practice. 单切口机器人手术:微创实践中新兴的里程碑。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-15 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004603
Hasibullah Aminpoor, Muhammad Khizar, Muhammad Zaib, Abeer Ijaz, Hasiba Karimi

Single-incision robotic surgery (SIRS) has emerged as a progression in minimally invasive practice, enabling complex operations through a single entry point. Modern systems such as the da Vinci SP (Intuitive Surgical, USA) and Versius (CMR Surgical, UK) allow multi-instrument articulation and high-definition visualization through a single port, overcoming the ergonomic and triangulation challenges of traditional laparoscopy. Recent evidence from South Korea, China, the USA, and Turkey demonstrates SIRS's feasibility, safety, and promising clinical outcomes across specialties including urology, gynecology, and general surgery. Studies report lower conversion rates, minimal postoperative pain, and enhanced cosmesis, though cost and learning curve remain limiting factors. As robotic technologies evolve, SIRS is poised to redefine minimally invasive standards through precision, reduced invasiveness, and improved recovery profiles. Rigorous multicenter trials and cost-effectiveness analyses are essential to confirm its broader clinical value.

单切口机器人手术(SIRS)作为微创实践的进展而出现,通过单一入口点实现复杂的手术。现代系统,如da Vinci SP (Intuitive Surgical,美国)和Versius (CMR Surgical,英国),允许通过单个端口实现多仪器连接和高清可视化,克服了传统腹腔镜的人体工程学和三角测量挑战。最近来自韩国、中国、美国和土耳其的证据表明,SIRS在泌尿科、妇科和普外科等专业的可行性、安全性和有希望的临床结果。研究报告了较低的转换率,最小的术后疼痛和增强的美容,尽管成本和学习曲线仍然是限制因素。随着机器人技术的发展,SIRS正准备通过精度、减少侵入性和改善恢复概况来重新定义微创标准。严格的多中心试验和成本效益分析对于证实其更广泛的临床价值至关重要。
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引用次数: 0
4D-Morphing biopolymers in reconstructive plastic surgery: implications, challenges and a call for clinical-translation. 4d变形生物聚合物在重建整形外科:影响,挑战和对临床翻译的呼吁。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004537
Asra Amjad, Maryam Waqar, Umair Ali, Raghabendra Kumar Mahato

The concept behind 4D morphing biopolymers represents a further improvement in reconstructive plastic surgery, as it can now create scaffolds that are stimulus-responsive, allowing them to exhibit flexibility in shape and functionality once implanted. Such materials have the potential to address the shortcomings of conventional autologous reconstruction through enhanced integration, vascularization, and minimally invasive implantation. Nevertheless, significant issues of translation, regulation, and ethics remain, underscoring the need for in vivo research, surgeon-engineer partnerships, and fair clinical practice.

4D变形生物聚合物背后的概念代表了重建整形手术的进一步进步,因为它现在可以制造出对刺激敏感的支架,一旦植入,就可以在形状和功能上表现出灵活性。这种材料有潜力通过增强整合、血管化和微创植入来解决传统自体重建的缺点。然而,翻译、监管和伦理方面的重大问题仍然存在,强调了体内研究、外科工程师合作和公平临床实践的必要性。
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引用次数: 0
Unmasking the malignancy beneath: re-evaluating splenic pseudocysts as potential precursors of lymphoma. 揭露下面的恶性肿瘤:重新评估脾脏假性囊肿作为淋巴瘤的潜在前体。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004541
Asra Amjad, Armeen Shahzad, Ruben Simon Roy, Raghabendra Kumar Mahato, Umair Ali
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引用次数: 0
Critical appraisal of "Evaluation of preoperative cervical internal carotid artery diameter as a predictor of cerebral hyperperfusion syndrome following revascularization surgery". “评估术前颈内动脉直径作为血运重建术后脑高灌注综合征的预测因子”的关键评价。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004566
Asra Amjad, Tooba Khurshid, Raghabendra Kumar Mahato, Umair Ali
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引用次数: 0
Spatial confinement of the AREG-SOX9 signaling circuit: rethinking tumor-stroma interactions in gastric cancer. AREG-SOX9信号通路的空间限制:重新思考胃癌中肿瘤-间质相互作用。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004538
Asra Amjad, Muhammad Talha Usman, Umair Ali, Raghabendra Kumar Mahato
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引用次数: 0
Photothermal nanoparticles delivering heat-triggered siRNA for tumor therapy. 光热纳米颗粒递送热触发siRNA用于肿瘤治疗。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004580
Fahad Amin, Ayesha Imran, Raghabendra Kumar Mahato
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引用次数: 0
Toward precision correction of OTUD5-mediated deubiquitylation defect in LINKED syndrome: a gene-editing paradigm for embryonic chromatin-remodeller disorders. 精确校正链接综合征中otud5介导的去泛素化缺陷:胚胎染色质重塑障碍的基因编辑范式。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004540
Asra Amjad, Ghanwa Imran, Umair Ali, Raghabendra Kumar Mahato
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引用次数: 0
Correspondence: Atypical spinal infections in the era of multidrug resistance: knowledge gaps and a proposed management algorithm. 通信:多药耐药时代的非典型脊柱感染:知识差距和提出的管理算法。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-12 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004525
Ahmad Furqan Anjum, Ali Rizwan Faisal, Hermann Yokolo
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引用次数: 0
Beyond hyperacusis: re-framing tonic tensor tympani syndrome as a middle-ear muscle dysregulation disorder in tinnitus clinics. 超越听觉亢进:重新构建强直性鼓室张量综合征作为耳鸣临床中耳肌肉失调障碍。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-11 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004516
Asra Amjad, Heena Arshad, Raghabendra Kumar Mahato, Umair Ali
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引用次数: 0
Post anaphylactic shock myocardial infarction (Kounis syndrome): a rare case report. 过敏性休克后心肌梗死(Kounis综合征)1例报道。
IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-11 eCollection Date: 2026-01-01 DOI: 10.1097/MS9.0000000000004544
Amir Abadi, Usra Ghanem, Shaker Nierat, Marwan Joma

Introduction and importance: Kounis syndrome is a rare condition described by acute coronary syndrome following an allergic reaction. This case report highlights a unique presentation of Kounis syndrome following moxifloxacin ingestion in a patient with vasculitis and a history of smoking.

Case presentation: A 55-year-old male smoker with a history of vasculitis presented with acute chest pain 1 hour after moxifloxacin ingestion. The patient developed epigastric pain, dizziness, and sweating. ECG showed ST-segment elevation in leads II, III, and aVF. Initial lab work revealed elevated eosinophil and basophil counts consistent with an allergic reaction. Cardiac catheterization identified significant stenosis in the left anterior descending artery, which was managed with a stent and a balloon. The patient was treated with corticosteroids, antihistamines, and dual antiplatelet therapy. Eosinophil and basophil counts became normal, and the patient was discharged in a stable condition.

Clinical discussion: This case showcases the intersection between allergic reactions and coronary events. Moxifloxacin is a known trigger for Kounis syndrome. The patient's vasculitis and smoking history likely predisposed him to coronary inflammation, making him susceptible to Kounis syndrome. While Kounis syndrome remains underdiagnosed due to the overlapping symptoms, timely recognition and management addressing both the allergic and cardiac components are crucial.

Conclusion: This article highlights the importance of considering Kounis syndrome in patients presenting with ACS following an allergic reaction, particularly in those with predisposing factors. Prompt diagnosis and intervention are essential to improve outcomes.

简介及重要性:库尼斯综合征是一种罕见的由急性冠状动脉综合征引起的过敏反应。本病例报告强调了一个独特的表现后,服用莫西沙星患者血管炎和吸烟史的Kounis综合征。病例介绍:55岁男性吸烟者,有血管炎病史,服用莫西沙星1小时后出现急性胸痛。患者出现上腹疼痛、头晕和出汗。心电图显示导联II、III和aVF st段抬高。最初的实验室检查显示嗜酸性粒细胞和嗜碱性粒细胞计数升高与过敏反应一致。心导管检查发现左前降支明显狭窄,使用支架和球囊进行治疗。患者接受皮质类固醇、抗组胺药和双重抗血小板治疗。患者的嗜酸性粒细胞和嗜碱性粒细胞计数恢复正常,出院时病情稳定。临床讨论:本病例显示了过敏反应与冠状动脉事件的交叉。莫西沙星是已知的库尼斯综合征的诱因。患者的血管炎和吸烟史可能使他易患冠状动脉炎症,使他易患Kounis综合征。虽然由于症状重叠,库尼斯综合征仍未得到充分诊断,但及时识别和管理过敏和心脏成分至关重要。结论:这篇文章强调了在出现过敏反应的ACS患者中考虑Kounis综合征的重要性,特别是那些有易感因素的患者。及时诊断和干预对改善预后至关重要。
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引用次数: 0
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Annals of Medicine and Surgery
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