Pub Date : 2019-01-01DOI: 10.1016/bs.armc.2019.06.004
J. T. Moreira-Filho, R. Dantas, M. R. Senger, Arthur C. Silva, D. Campos, E. Muratov, F. Silva-Junior, C. Andrade, B. J. Neves
{"title":"Shortcuts to schistosomiasis drug discovery: The state-of-the-art","authors":"J. T. Moreira-Filho, R. Dantas, M. R. Senger, Arthur C. Silva, D. Campos, E. Muratov, F. Silva-Junior, C. Andrade, B. J. Neves","doi":"10.1016/bs.armc.2019.06.004","DOIUrl":"https://doi.org/10.1016/bs.armc.2019.06.004","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.armc.2019.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/BS.ARMC.2019.05.006
G. Poce, S. Consalvi, Giulia Venditti, Cristina Scarpecci, M. Biava
{"title":"Development of MmpL3 inhibitors for tuberculosis treatment","authors":"G. Poce, S. Consalvi, Giulia Venditti, Cristina Scarpecci, M. Biava","doi":"10.1016/BS.ARMC.2019.05.006","DOIUrl":"https://doi.org/10.1016/BS.ARMC.2019.05.006","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.ARMC.2019.05.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/BS.ARMC.2019.04.001
P. Cheuka, G. Mayoka, John Okombo, K. Chibale
{"title":"Medicinal chemistry progression of antimalarial hits from phenotypic whole cell screening of SoftFocus libraries","authors":"P. Cheuka, G. Mayoka, John Okombo, K. Chibale","doi":"10.1016/BS.ARMC.2019.04.001","DOIUrl":"https://doi.org/10.1016/BS.ARMC.2019.04.001","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.ARMC.2019.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54060771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/bs.armc.2019.07.001
Esther Fernández, M. Castellote, M. J. Chaparro, Beatriz Díaz, J. Fernández, Mariola Gordo, Laura de las Heras, María L León, Lourdes Rueda, Félix Calderón
{"title":"A decade of malaria phenotypic screenings: Key lessons on the discovery and development of new antimalarial drugs","authors":"Esther Fernández, M. Castellote, M. J. Chaparro, Beatriz Díaz, J. Fernández, Mariola Gordo, Laura de las Heras, María L León, Lourdes Rueda, Félix Calderón","doi":"10.1016/bs.armc.2019.07.001","DOIUrl":"https://doi.org/10.1016/bs.armc.2019.07.001","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.armc.2019.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/BS.ARMC.2019.05.005
D. Muñoz-Torrero, R. Lavilla, F. J. Pérez‐Areales, Ouldouz Ghashghaei
{"title":"Multicomponent reactions: A mighty journey partner for infectious tropical disease drug discovery","authors":"D. Muñoz-Torrero, R. Lavilla, F. J. Pérez‐Areales, Ouldouz Ghashghaei","doi":"10.1016/BS.ARMC.2019.05.005","DOIUrl":"https://doi.org/10.1016/BS.ARMC.2019.05.005","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.ARMC.2019.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/BS.ARMC.2019.06.002
S. Gemma, Stefano Federico, Simone Brogi, M. Brindisi, S. Butini, G. Campiani
{"title":"Dealing with schistosomiasis: Current drug discovery strategies","authors":"S. Gemma, Stefano Federico, Simone Brogi, M. Brindisi, S. Butini, G. Campiani","doi":"10.1016/BS.ARMC.2019.06.002","DOIUrl":"https://doi.org/10.1016/BS.ARMC.2019.06.002","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/BS.ARMC.2019.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/bs.armc.2019.06.003
N. Willand, Marion Flipo, Baptiste Villemagne, A. Baulard, B. Déprez
{"title":"Recent advances in the design of inhibitors of mycobacterial transcriptional regulators to boost thioamides anti-tubercular activity and circumvent acquired-resistance","authors":"N. Willand, Marion Flipo, Baptiste Villemagne, A. Baulard, B. Déprez","doi":"10.1016/bs.armc.2019.06.003","DOIUrl":"https://doi.org/10.1016/bs.armc.2019.06.003","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.armc.2019.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54061580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1016/bs.armc.2019.05.001
A. M. Thompson, W. Denny
{"title":"Inhibitors of enzymes in the electron transport chain of Mycobacterium tuberculosis","authors":"A. M. Thompson, W. Denny","doi":"10.1016/bs.armc.2019.05.001","DOIUrl":"https://doi.org/10.1016/bs.armc.2019.05.001","url":null,"abstract":"","PeriodicalId":8033,"journal":{"name":"Annual Reports in Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/bs.armc.2019.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54060816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}