Pub Date : 2025-12-13DOI: 10.1016/j.aninu.2025.09.012
Jie Wang, Hao Wang, Yuchen Zhao, Tongxi Zhao, Tao Ding, Shiyou Chen, Songtao Lin, Xinmin Du, Yaping Zhu, Xiaofang Liang, Min Xue
The projected expansion of aquaculture production cannot rely solely on fishmeal (FM) due to its unsustainability and increasing price. Therefore, novel FM alternatives with high nutritional value, excellent digestibility, great palatability, low toxicity, and abundance without competing with human food sources is a crucial strategy for promoting sustainable aquaculture. Cottonseed proteins have been identified as valuable non-grain protein sources in aquaculture, with a production history tracing back to the 1950s. In recent years, the advancements in processing equipment and technologies have successfully optimized the production of cottonseed proteins that meet desired attributes of FM alternatives. Cottonseed protein concentrate is a prime example, obtained through low-temperature solvent extraction, de-gossypolization, and moderate raffinose isolation to enhance its nutritional value and palatability. This review provides a comprehensive overview of the research advancements concerning cottonseed proteins in aquafeed, including a detailed examination of their production processes, physicochemical properties, feed processing characteristics, nutritional values, and a meta-analysis on the growth performance of aquatic animals when cottonseed proteins are used as alternatives to fish meal in feed.
{"title":"Cottonseed proteins: A promising and undervalued non-grain protein source for aquafeed","authors":"Jie Wang, Hao Wang, Yuchen Zhao, Tongxi Zhao, Tao Ding, Shiyou Chen, Songtao Lin, Xinmin Du, Yaping Zhu, Xiaofang Liang, Min Xue","doi":"10.1016/j.aninu.2025.09.012","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.09.012","url":null,"abstract":"The projected expansion of aquaculture production cannot rely solely on fishmeal (FM) due to its unsustainability and increasing price. Therefore, novel FM alternatives with high nutritional value, excellent digestibility, great palatability, low toxicity, and abundance without competing with human food sources is a crucial strategy for promoting sustainable aquaculture. Cottonseed proteins have been identified as valuable non-grain protein sources in aquaculture, with a production history tracing back to the 1950s. In recent years, the advancements in processing equipment and technologies have successfully optimized the production of cottonseed proteins that meet desired attributes of FM alternatives. Cottonseed protein concentrate is a prime example, obtained through low-temperature solvent extraction, de-gossypolization, and moderate raffinose isolation to enhance its nutritional value and palatability. This review provides a comprehensive overview of the research advancements concerning cottonseed proteins in aquafeed, including a detailed examination of their production processes, physicochemical properties, feed processing characteristics, nutritional values, and a meta-analysis on the growth performance of aquatic animals when cottonseed proteins are used as alternatives to fish meal in feed.","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"20 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1016/j.aninu.2025.10.003
Tong Li, Min Li, Min Xue, Jie Wang, Hao Wang, Lixin Wu, Yaping Zhu, Wenhao Zhou, Xiaofang Liang
Lipopeptides are versatile surface-active natural products that act as emulsifiers, enhance lipid utilization, and exhibit broad-spectrum antimicrobial properties. Whether lipopeptides have the potential to improve energy efficiency and fight bacterial infection in largemouth bass (Micropterus salmoides) has not been reported. In this study, a total of 300 juvenile largemouth bass (initial body weight 14.67 ± 0.01 g) were randomly divided into four groups with five replicates per group (n = 5), each replicate consisting of 30 fish. The fish were fed four experimental diets for 10 weeks: 10.50% lipid (low-lipid, LL), 10.50% lipid + 0.05% lipopeptides (low-lipid with lipopeptides, LLLP), 13.00% lipid (high-lipid, HL), and 13.00% lipid + 0.05% lipopeptides (high-lipid with lipopeptides, HLLP). Two-way ANOVA showed neither lipid levels nor lipopeptides had a significant effect on survival rate and weight gain (P > 0.05). However, the largemouth bass fed low-lipid diets exhibited significantly higher feed intake to meet energy demands, resulting in an increased feed conversion ratio (P = 0.004), which was then decreased after lipopeptide supplementation (P = 0.061). High-lipid levels led to a significant increase (P < 0.001) in plasma total cholesterol (TC) and liver lipid content, and the addition of lipopeptides significantly improved the above conditions (P < 0.001). Mechanistically, lipopeptides upregulated lipid catabolism (hormonesensitive triglyceride lipase, Hsl; P < 0.001) and fatty acid oxidation genes (carnitine palmitoyltransferase 1 α, Cpt1α; P = 0.004), while suppressing lipogenesis gene (fatty acid synthase, Fasn; P = 0.045). Pathway analysis revealed that lipopeptides coordinately regulated energy metabolism by involving AMP-activated protein kinase (AMPK) energy sensing and cyclic-AMP (cAMP) response element-binding protein (Creb) signaling cascades. In an Edwardsiella tarda challenge, lipopeptide supplementation significantly reduced intestinal pro-inflammatory factors (interleukin [IL]-8 [P = 0.007] and IL-1β [P = 0.006]) and enhanced immune function, as evidenced by elevated levels of anti-inflammatory transforming growth factor β1 (TGF-β1; P = 0.011) and immunoglobulin M (IgM; P = 0.003). This study provides a comprehensive exploration of lipopeptide-mediated regulatory mechanisms under different dietary lipid levels, highlighting their potential for optimizing feed formulations and improving lipid metabolic health in aquaculture species.
脂肽是多功能的表面活性天然产物，作为乳化剂，提高脂质利用率，并表现出广谱抗菌特性。脂肽在大口黑鲈体内是否具有提高能量利用效率和抵抗细菌感染的潜力尚未见报道。试验选取初始体重14.67±0.01 g的大口黑鲈幼鱼300尾，随机分为4组，每组5个重复（n = 5），每个重复30尾。饲喂4种试验饲料，分别为10.50%脂质（低脂，LL）、10.50%脂质+ 0.05%脂肽（低脂带脂肽，LLLP）、13.00%脂质（高脂，HL）和13.00%脂质+ 0.05%脂肽（高脂带脂肽，HLLP），为期10周。双因素方差分析显示，脂质水平和脂肽对存活率和体重增加均无显著影响（P > 0.05）。低脂饲料显著提高了大口黑鲈的采食量以满足能量需求（P = 0.004），提高了饲料系数（P = 0.061），添加脂肽后降低了饲料系数。高脂水平导致血浆总胆固醇（TC）和肝脏脂质含量显著升高（P < 0.001），添加脂肽可显著改善上述情况（P < 0.001）。在机制上，脂肽上调脂质分解代谢（激素敏感型甘油三酯脂肪酶，hs1; P < 0.001）和脂肪酸氧化基因（肉碱棕榈酰基转移酶1α， Cpt1α; P = 0.004），同时抑制脂肪生成基因（脂肪酸合成酶，Fasn; P = 0.045）。途径分析表明，脂肽通过参与amp活化蛋白激酶（AMPK）能量感知和环amp （cAMP）反应元件结合蛋白（Creb）信号级联来协调调节能量代谢。在迟发爱德华氏菌攻击中，补充脂肽可显著降低肠道促炎因子（白细胞介素[IL]-8 [P = 0.007]和IL-1β [P = 0.006]），增强免疫功能，其证据是抗炎转化生长因子β1 （TGF-β1, P = 0.011）和免疫球蛋白M （IgM, P = 0.003）水平升高。本研究全面探索了不同饲料脂质水平下脂肽介导的调节机制，强调了其在优化饲料配方和改善水产养殖物种脂质代谢健康方面的潜力。
{"title":"Lipopeptides modulate lipid metabolism and immune performance in largemouth bass (Micropterus salmoides) across dietary lipid levels","authors":"Tong Li, Min Li, Min Xue, Jie Wang, Hao Wang, Lixin Wu, Yaping Zhu, Wenhao Zhou, Xiaofang Liang","doi":"10.1016/j.aninu.2025.10.003","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.10.003","url":null,"abstract":"Lipopeptides are versatile surface-active natural products that act as emulsifiers, enhance lipid utilization, and exhibit broad-spectrum antimicrobial properties. Whether lipopeptides have the potential to improve energy efficiency and fight bacterial infection in largemouth bass (<ce:italic>Micropterus salmoides</ce:italic>) has not been reported. In this study, a total of 300 juvenile largemouth bass (initial body weight 14.67 ± 0.01 g) were randomly divided into four groups with five replicates per group (<ce:italic>n</ce:italic> = 5), each replicate consisting of 30 fish. The fish were fed four experimental diets for 10 weeks: 10.50% lipid (low-lipid, LL), 10.50% lipid + 0.05% lipopeptides (low-lipid with lipopeptides, LLLP), 13.00% lipid (high-lipid, HL), and 13.00% lipid + 0.05% lipopeptides (high-lipid with lipopeptides, HLLP). Two-way ANOVA showed neither lipid levels nor lipopeptides had a significant effect on survival rate and weight gain (<ce:italic>P</ce:italic> > 0.05). However, the largemouth bass fed low-lipid diets exhibited significantly higher feed intake to meet energy demands, resulting in an increased feed conversion ratio (<ce:italic>P</ce:italic> = 0.004), which was then decreased after lipopeptide supplementation (<ce:italic>P</ce:italic> = 0.061). High-lipid levels led to a significant increase (<ce:italic>P</ce:italic> < 0.001) in plasma total cholesterol (TC) and liver lipid content, and the addition of lipopeptides significantly improved the above conditions (<ce:italic>P</ce:italic> < 0.001). Mechanistically, lipopeptides upregulated lipid catabolism (hormonesensitive triglyceride lipase, <ce:italic>Hsl</ce:italic>; <ce:italic>P</ce:italic> < 0.001) and fatty acid oxidation genes (carnitine palmitoyltransferase 1 <ce:italic>α</ce:italic>, <ce:italic>Cpt1α</ce:italic>; <ce:italic>P</ce:italic> = 0.004), while suppressing lipogenesis gene (fatty acid synthase, <ce:italic>Fasn</ce:italic>; <ce:italic>P</ce:italic> = 0.045). Pathway analysis revealed that lipopeptides coordinately regulated energy metabolism by involving AMP-activated protein kinase (AMPK) energy sensing and cyclic-AMP (cAMP) response element-binding protein (Creb) signaling cascades. In an <ce:italic>Edwardsiella tarda</ce:italic> challenge, lipopeptide supplementation significantly reduced intestinal pro-inflammatory factors (interleukin [IL]-8 [<ce:italic>P</ce:italic> = 0.007] and IL-1β [<ce:italic>P</ce:italic> = 0.006]) and enhanced immune function, as evidenced by elevated levels of anti-inflammatory transforming growth factor β1 (TGF-β1; <ce:italic>P =</ce:italic> 0.011) and immunoglobulin M (IgM; <ce:italic>P</ce:italic> = 0.003). This study provides a comprehensive exploration of lipopeptide-mediated regulatory mechanisms under different dietary lipid levels, highlighting their potential for optimizing feed formulations and improving lipid metabolic health in aquaculture species.","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"5 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145704935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guanidinoacetic acid (GAA) increases milk production in dairy cows by promoting milk fatty acid (FA) and protein synthesis; however, its mechanism is unclear. We hypothesized that provision of rumen-protected GAA (RPGAA) would increase milk production, and milk fat and protein synthesis, while revealing the underlying mechanisms. Forty-four multiparous Holstein dairy cows (33.5 ± 1.31 kg/d of milk yield, 667 ± 11.8 kg of body weight, and 38.5 ± 2.14 d in milk [DIM]) were blocked by daily milk yield and DIM, and allocated to different treatments in a randomized-block design, namely, the control (without RPGAA), low-RPGAA (0.18 g/kg DM of GAA), medium-RPGAA (0.36 g/kg DM of GAA), and high-RPGAA (0.54 g/kg DM of GAA) groups. The experiment lasted for 95 d, including a 10-d covariate period, a 15-d adaptation period, and a 70-d sampling period. Although the DM intake and BW were not impacted (P > 0.05), the yields of actual milk, 4% fat-corrected milk, and energy-corrected milk increased linearly and quadratically (P < 0.05) with RPGAA supplementation; milk fat and protein percentage also showed quadratic increases (P < 0.05). The de novo and mixed production of FA in milk increased linearly and quadratically (P < 0.05), whereas that of preformed FA was increased quadratically (P < 0.01). Administration of RPGAA linearly increased the daily secretion yields of Arg, Cys, His, Ser, Thr, Trp, and Tyr (P < 0.05), and quadratically increased those of Ile, Lys, Met, Phe, Asp, and Glu in milk (P < 0.05). Furthermore, the apparent digestibilities of DM, OM, CP, and EE increased quadratically (P < 0.05), and those of NDF and ADF increased linearly (P < 0.05), following GAA supplementation. Serum concentrations of glucose, total protein, albumin, Arg, and creatine increased linearly (P < 0.05); concentrations of insulin-like growth factor 1, estradiol, and prolactin increased quadratically (P < 0.05), and that of blood urea nitrogen decreased quadratically (P = 0.018). Furthermore, addition of 0.36 g/kg DM of GAA from RPGAA promoted the expression of proteins concerned with mammary gland proliferation, FA synthesis, and milk protein synthesis, which were done in tissue biopsies. These results indicate that RPGAA provision enhanced milk production, FA synthesis, and milk protein synthesis by promoting the expression of proteins involved in mammary gland development, FA synthesis, and milk protein synthesis.
{"title":"Influences of dietary guanidinoacetic acid supplementation on performance and proteins involved in milk fat and protein synthesis in dairy cows","authors":"Jing Zhang, Yanchu Tang, Changjian Xue, Jiaojiao Lang, Wenjie Huo, Caixia Pei, Qiang Liu","doi":"10.1016/j.aninu.2025.07.008","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.07.008","url":null,"abstract":"Guanidinoacetic acid (GAA) increases milk production in dairy cows by promoting milk fatty acid (FA) and protein synthesis; however, its mechanism is unclear. We hypothesized that provision of rumen-protected GAA (RPGAA) would increase milk production, and milk fat and protein synthesis, while revealing the underlying mechanisms. Forty-four multiparous Holstein dairy cows (33.5 ± 1.31 kg/d of milk yield, 667 ± 11.8 kg of body weight, and 38.5 ± 2.14 d in milk [DIM]) were blocked by daily milk yield and DIM, and allocated to different treatments in a randomized-block design, namely, the control (without RPGAA), low-RPGAA (0.18 g/kg DM of GAA), medium-RPGAA (0.36 g/kg DM of GAA), and high-RPGAA (0.54 g/kg DM of GAA) groups. The experiment lasted for 95 d, including a 10-d covariate period, a 15-d adaptation period, and a 70-d sampling period. Although the DM intake and BW were not impacted (<ce:italic>P</ce:italic> > 0.05), the yields of actual milk, 4% fat-corrected milk, and energy-corrected milk increased linearly and quadratically (<ce:italic>P</ce:italic> < 0.05) with RPGAA supplementation; milk fat and protein percentage also showed quadratic increases (<ce:italic>P</ce:italic> < 0.05). The de novo and mixed production of FA in milk increased linearly and quadratically (<ce:italic>P</ce:italic> < 0.05), whereas that of preformed FA was increased quadratically (<ce:italic>P</ce:italic> < 0.01). Administration of RPGAA linearly increased the daily secretion yields of Arg, Cys, His, Ser, Thr, Trp, and Tyr (<ce:italic>P</ce:italic> < 0.05), and quadratically increased those of Ile, Lys, Met, Phe, Asp, and Glu in milk (<ce:italic>P</ce:italic> < 0.05). Furthermore, the apparent digestibilities of DM, OM, CP, and EE increased quadratically (<ce:italic>P</ce:italic> < 0.05), and those of NDF and ADF increased linearly (<ce:italic>P</ce:italic> < 0.05), following GAA supplementation. Serum concentrations of glucose, total protein, albumin, Arg, and creatine increased linearly (<ce:italic>P</ce:italic> < 0.05); concentrations of insulin-like growth factor 1, estradiol, and prolactin increased quadratically (<ce:italic>P</ce:italic> < 0.05), and that of blood urea nitrogen decreased quadratically (<ce:italic>P</ce:italic> = 0.018). Furthermore, addition of 0.36 g/kg DM of GAA from RPGAA promoted the expression of proteins concerned with mammary gland proliferation, FA synthesis, and milk protein synthesis, which were done in tissue biopsies. These results indicate that RPGAA provision enhanced milk production, FA synthesis, and milk protein synthesis by promoting the expression of proteins involved in mammary gland development, FA synthesis, and milk protein synthesis.","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"22 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145704936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inactivated probiotics can exhibit beneficial properties similar to live probiotics while offering greater stability and safety. However, the understanding of how inactivated probiotics affect the growth, health, and gut microbiota of neonatal calves is still limited. This study investigated the effect of inactivated Lactobacillus acidophilus (ILA, ≥ 1 × 108 CFU equivalents/mL) on growth performance, blood parameters, and fecal fermentation and microbiota of neonatal dairy calves. Forty female Holstein calves (37.92 ± 2.04 kg; 2.45 ± 0.96 d) were randomly assigned to a basal diet supplemented with 0 (CK), 2, 4, or 6 mL/day of ILA (ILA2, ILA4, and ILA6) until 54 days of age. The results showed that while ILA supplementation did not affect body weight or feed efficiency, it linearly increased structural growth indices (body length and heart girth) at both 30 and 54 days of age (all P < 0.05). Crucially, ILA significantly reduced fecal scores (P < 0.001) and diarrhea incidence (P = 0.019), particularly in the ILA4 group. Serum analysis revealed that ILA elevated the levels of immunoglobulins A, G, and M (all P < 0.001), as well as total protein, globulin, glucose, and superoxide dismutase (all P < 0.05), indicating improved immune status and metabolic health. Furthermore, ILA modulated fecal fermentation, inducing a quadratic response in acetic acid (P = 0.005) and total volatile fatty acids (P = 0.010). Microbiome analysis indicated linear increases in Firmicutes, Proteobacteria, and the genus Faecalibacterium, coupled with linear decreases in Bacteroidota, Spirochaetota, and Rikenellaceae_RC9_gut_group (all P < 0.05). This ILA-induced microbial shift enriched functional pathways associated with transport, transcription, replication, and butanoate metabolism compared with the CK group (all P < 0.05). Spearman correlation analysis identified significant correlations between fecal microbiota composition and host growth, metabolism, and health. Collectively, the beneficial effects of ILA on structural growth, diarrhea reduction, fecal fermentation, and metabolic health in calves are closely related to dynamic changes in fecal microbiota. These beneficial effects may stem from ILA's ability to modulate the composition, diversity, and function of the gut microbiota. This study offers a scientific basis for the application of ILA in calf production.
{"title":"Effects of inactivated Lactobacillus acidophilus on growth performance, blood parameters, fecal fermentation and microbiota in neonatal Holstein calves","authors":"Zexi Cai, Meng Wang, Zhenyu Xian, Yaru Hu, Yanhua Pan, Xin Feng, Baoli Sun, Ming Deng, Yaokun Li, Guangbin Liu, Wenfeng Hu, Dewu Liu, Yongqing Guo","doi":"10.1016/j.aninu.2025.11.002","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.11.002","url":null,"abstract":"Inactivated probiotics can exhibit beneficial properties similar to live probiotics while offering greater stability and safety. However, the understanding of how inactivated probiotics affect the growth, health, and gut microbiota of neonatal calves is still limited. This study investigated the effect of inactivated <ce:italic>Lactobacillus acidophilus</ce:italic> (ILA, ≥ 1 × 10<ce:sup loc=\"post\">8</ce:sup> CFU equivalents/mL) on growth performance, blood parameters, and fecal fermentation and microbiota of neonatal dairy calves. Forty female Holstein calves (37.92 ± 2.04 kg; 2.45 ± 0.96 d) were randomly assigned to a basal diet supplemented with 0 (CK), 2, 4, or 6 mL/day of ILA (ILA2, ILA4, and ILA6) until 54 days of age. The results showed that while ILA supplementation did not affect body weight or feed efficiency, it linearly increased structural growth indices (body length and heart girth) at both 30 and 54 days of age (all <ce:italic>P</ce:italic> < 0.05). Crucially, ILA significantly reduced fecal scores (<ce:italic>P</ce:italic> < 0.001) and diarrhea incidence (<ce:italic>P</ce:italic> = 0.019), particularly in the ILA4 group. Serum analysis revealed that ILA elevated the levels of immunoglobulins A, G, and M (all <ce:italic>P</ce:italic> < 0.001), as well as total protein, globulin, glucose, and superoxide dismutase (all <ce:italic>P</ce:italic> < 0.05), indicating improved immune status and metabolic health. Furthermore, ILA modulated fecal fermentation, inducing a quadratic response in acetic acid (<ce:italic>P</ce:italic> = 0.005) and total volatile fatty acids (<ce:italic>P</ce:italic> = 0.010). Microbiome analysis indicated linear increases in Firmicutes, Proteobacteria, and the genus <ce:italic>Faecalibacterium</ce:italic>, coupled with linear decreases in Bacteroidota, Spirochaetota, and <ce:italic>Rikenellaceae_RC9_gut_group</ce:italic> (all <ce:italic>P</ce:italic> < 0.05). This ILA-induced microbial shift enriched functional pathways associated with transport, transcription, replication, and butanoate metabolism compared with the CK group (all <ce:italic>P</ce:italic> < 0.05). Spearman correlation analysis identified significant correlations between fecal microbiota composition and host growth, metabolism, and health. Collectively, the beneficial effects of ILA on structural growth, diarrhea reduction, fecal fermentation, and metabolic health in calves are closely related to dynamic changes in fecal microbiota. These beneficial effects may stem from ILA's ability to modulate the composition, diversity, and function of the gut microbiota. This study offers a scientific basis for the application of ILA in calf production.","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"28 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145704937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-06DOI: 10.1016/j.aninu.2025.07.007
Yongkang Chen, Xiaomin Li, Anqi Chen, Zhihong Liao, Xingyu Gu, Xuanqi Chen, Tao Ye, Wenrui Zhang, Xuanshu He, Wenjie Li, Bo Zhu, Peng Hu, Xinliang Zhu, Zhenyu Du, Wei Zhao, Jin Niu
{"title":"A novel black soldier fly protein hydrolysate improves the muscle growth of rainbow trout (Oncorhynchus mykiss) via the PI3K/AKT/mTOR pathway","authors":"Yongkang Chen, Xiaomin Li, Anqi Chen, Zhihong Liao, Xingyu Gu, Xuanqi Chen, Tao Ye, Wenrui Zhang, Xuanshu He, Wenjie Li, Bo Zhu, Peng Hu, Xinliang Zhu, Zhenyu Du, Wei Zhao, Jin Niu","doi":"10.1016/j.aninu.2025.07.007","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.07.007","url":null,"abstract":"","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"20 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145689951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacillus velezensis CML532 supplementation improved growth performance, protein digestion, and gut health in broilers fed with corn-miscellaneous meal-based low-protein diets","authors":"Jinping Wang, Xiaodan Zhang, Caiwei Luo, Mi Wang, Xinzhi Wang, Yuming Guo","doi":"10.1016/j.aninu.2025.09.010","DOIUrl":"https://doi.org/10.1016/j.aninu.2025.09.010","url":null,"abstract":"","PeriodicalId":8184,"journal":{"name":"Animal Nutrition","volume":"2 1","pages":""},"PeriodicalIF":6.3,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145689950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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